#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P48281 uniprotkb:Q13573 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531 psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short) psi-mi:"MI:0096"(pull down) Barry et al. (2003) pubmed:12529369 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6391996 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791 refseq:NP_036377.1|ensembl:ENSG00000100603(gene)|ensembl:ENST00000261531(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048385"(regulation of retinoic acid receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070564"(positive regulation of vitamin D receptor signaling pathway)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|dip:DIP-34800N - - - figure legend:2D|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/15 2014/10/16 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606 intact-crc:C3B1E7A439979939|rigid:Jbf6vNjf4ywyi8Sb+1aL8Oacz9k false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28704 uniprotkb:P48281 intact:EBI-6392036|ensembl:ENSMUSP00000133775|uniprotkb:P33243 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 psi-mi:rxrb_mouse(display_long)|uniprotkb:Rxrb(gene name)|psi-mi:Rxrb(display_short)|uniprotkb:Nr2b2(gene name synonym)|uniprotkb:MHC class I regulatory element-binding protein H-2RIIBP(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:Retinoid X receptor beta(gene name synonym) psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Barry et al. (2003) pubmed:12529369 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392066 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039656(gene)|ensembl:ENSMUST00000174299(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9623433|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|refseq:NP_001192145.1|refseq:NP_035436.1 refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791 - - - figure legend:4B|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/15 2014/10/16 rogid:E0PE8gFB89+zqEkwgdKZGkahpxg10090 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 intact-crc:85577971974957D8|rigid:dTD2jkKQr48Sj1D75F6bz5MHkP0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P48281 uniprotkb:Q00403 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 intact:EBI-389564|uniprotkb:A8K1A7|uniprotkb:Q5JS30|ensembl:ENSP00000359531 psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:tf2b_human(display_long)|uniprotkb:GTF2B(gene name)|psi-mi:GTF2B(display_short)|uniprotkb:TF2B(gene name synonym)|uniprotkb:TFIIB(gene name synonym)|uniprotkb:General transcription factor TFIIB(gene name synonym)|uniprotkb:S300-II(gene name synonym) psi-mi:"MI:0096"(pull down) Barry et al. (2003) pubmed:12529369 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392032 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791 refseq:NP_001505.1|ensembl:ENSG00000137947(gene)|ensembl:ENST00000370500(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005694"(chromosome)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019083"(viral transcription)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000812(Transcription factor TFIIB related)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR013150(Transcription factor TFIIB, cyclin-related)|interpro:IPR013763(Cyclin-related)|interpro:IPR023486|interpro:IPR036915|mint:Q00403|rcsb pdb:1C9B|rcsb pdb:1DL6|rcsb pdb:1RLY|rcsb pdb:1RO4|rcsb pdb:1TFB|rcsb pdb:1VOL|rcsb pdb:2PHG|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5WH1|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|dip:DIP-1077N - - - figure legend:4B|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/15 2014/10/16 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 rogid:mVGHi0jBibSFHpBrVTGHnRm4gXw9606 intact-crc:397B900B59AC54C0|rigid:cIA3uzBAe/S4r3QCCBJSmsZs1ts false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P19793 uniprotkb:P48281 intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Barry et al. (2003) pubmed:12529369 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392028 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29 refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791 - - - figure legend:4A|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/15 2014/10/16 rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 intact-crc:33BB3C7DACC8B703|rigid:oQEq4eXthLhOrkOm6ZTFGF7vUzI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48281 uniprotkb:Q00403 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 intact:EBI-389564|uniprotkb:A8K1A7|uniprotkb:Q5JS30|ensembl:ENSP00000359531 psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:tf2b_human(display_long)|uniprotkb:GTF2B(gene name)|psi-mi:GTF2B(display_short)|uniprotkb:TF2B(gene name synonym)|uniprotkb:TFIIB(gene name synonym)|uniprotkb:General transcription factor TFIIB(gene name synonym)|uniprotkb:S300-II(gene name synonym) psi-mi:"MI:0018"(two hybrid) Barry et al. (2003) pubmed:12529369 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392024 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791 refseq:NP_001505.1|ensembl:ENSG00000137947(gene)|ensembl:ENST00000370500(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005694"(chromosome)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019083"(viral transcription)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000812(Transcription factor TFIIB related)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR013150(Transcription factor TFIIB, cyclin-related)|interpro:IPR013763(Cyclin-related)|interpro:IPR023486|interpro:IPR036915|mint:Q00403|rcsb pdb:1C9B|rcsb pdb:1DL6|rcsb pdb:1RLY|rcsb pdb:1RO4|rcsb pdb:1TFB|rcsb pdb:1VOL|rcsb pdb:2PHG|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5WH1|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|dip:DIP-1077N - - - figure legend:4A|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/15 2014/10/16 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 rogid:mVGHi0jBibSFHpBrVTGHnRm4gXw9606 intact-crc:DC5C90366D7F9E73|rigid:cIA3uzBAe/S4r3QCCBJSmsZs1ts false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48281 uniprotkb:Q13573 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531 psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short) psi-mi:"MI:0018"(two hybrid) Barry et al. (2003) pubmed:12529369 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6391985 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791 refseq:NP_036377.1|ensembl:ENSG00000100603(gene)|ensembl:ENST00000261531(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048385"(regulation of retinoic acid receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070564"(positive regulation of vitamin D receptor signaling pathway)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|dip:DIP-34800N - - - figure legend:2A , B|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/15 2014/10/16 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606 intact-crc:B6C8C77CDE795F59|rigid:Jbf6vNjf4ywyi8Sb+1aL8Oacz9k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48281 uniprotkb:Q9Y6Q9 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45 psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Barry et al. (2003) pubmed:12529369 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392005 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791 refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N - - - figure legend:3A|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/15 2014/10/16 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606 intact-crc:D0906E497B75B9CC|rigid:hSVECXE7TAf6rdE9mWPQJy2o7uA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48281 uniprotkb:Q925T6 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 intact:EBI-537752|uniprotkb:Q8BLQ3|uniprotkb:Q8C0T3|uniprotkb:Q925T5|uniprotkb:Q925T7|ensembl:ENSMUSP00000123234 psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:grip1_mouse(display_long)|uniprotkb:Grip1(gene name)|psi-mi:Grip1(display_short) psi-mi:"MI:0018"(two hybrid) Barry et al. (2003) pubmed:12529369 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392000 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791 refseq:NP_001264224.1|refseq:NP_083012.1|refseq:NP_570961.1|refseq:NP_597699.1|refseq:NP_001264221.1|refseq:NP_001264223.1|ensembl:ENSMUSG00000034813(gene)|ensembl:ENSMUST00000138410(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030026|interpro:IPR036034|interpro:IPR041489|interpro:IPR043545|mint:Q925T6|rcsb pdb:1V5Q|reactome:R-MMU-416993 - - - figure legend:3A|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/15 2014/10/16 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 rogid:nQDCS/yQb0DlZs+60Vf3Q3hbECk10090 intact-crc:37415879242FAFD8|rigid:aWsYtajBOPHb7PCpdUdfL1E3NVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q925T6 uniprotkb:P48281 intact:EBI-537752|uniprotkb:Q8BLQ3|uniprotkb:Q8C0T3|uniprotkb:Q925T5|uniprotkb:Q925T7|ensembl:ENSMUSP00000123234 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 psi-mi:grip1_mouse(display_long)|uniprotkb:Grip1(gene name)|psi-mi:Grip1(display_short) psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Barry et al. (2003) pubmed:12529369 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392016 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001264224.1|refseq:NP_083012.1|refseq:NP_570961.1|refseq:NP_597699.1|refseq:NP_001264221.1|refseq:NP_001264223.1|ensembl:ENSMUSG00000034813(gene)|ensembl:ENSMUST00000138410(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030026|interpro:IPR036034|interpro:IPR041489|interpro:IPR043545|mint:Q925T6|rcsb pdb:1V5Q|reactome:R-MMU-416993 refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791 - - - figure legend:3B|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/15 2014/10/16 rogid:nQDCS/yQb0DlZs+60Vf3Q3hbECk10090 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 intact-crc:08ACAC00FE440C4F|rigid:aWsYtajBOPHb7PCpdUdfL1E3NVI false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9Y6Q9 uniprotkb:P48281 intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym) psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Barry et al. (2003) pubmed:12529369 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392020 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791 - - - figure legend:3B|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/15 2014/10/16 rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 intact-crc:3E9CF35AE850A33F|rigid:hSVECXE7TAf6rdE9mWPQJy2o7uA false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)