#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O35177 uniprotkb:Q15654 intact:EBI-2642891|uniprotkb:Q8BJL8|uniprotkb:Q8BMI9|uniprotkb:Q8BM94|uniprotkb:Q8BK90|uniprotkb:Q99KE7|uniprotkb:Q8BL52|ensembl:ENSMUSP00000021794 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:casl_mouse(display_long)|uniprotkb:Casl(gene name synonym)|uniprotkb:CRK-associated substrate-related protein(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 9(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Nedd9(gene name)|psi-mi:Nedd9(display_short) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-5795758|imex:IM-16894-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001104794.1|refseq:NP_059492.3|ensembl:ENSMUSG00000021365(gene)|ensembl:ENSMUST00000021794(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0040008"(regulation of growth)|go:"GO:0051301"(cell division)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR035746|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|dip:DIP-57058N refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:Table 1 and Fig 5.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:M/DE7RwmYizqy+SKJvp0M1f1odY10090 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:940B42BDFD069D0A|rigid:3ViBkCmxv/aEl3USe3BcyfK8mb8 false sufficient binding region:163-315 sufficient binding region:276-393 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9QY81 uniprotkb:Q15654 intact:EBI-5796508|uniprotkb:Q3U031|uniprotkb:Q69ZW2|uniprotkb:Q7TQM1|ensembl:ENSMUSP00000032179 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:po210_mouse(display_long)|uniprotkb:Nup210(gene name)|psi-mi:Nup210(display_short)|uniprotkb:Kiaa0906(gene name synonym)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-5796496|imex:IM-16894-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061285.2|ensembl:ENSMUSG00000030091(gene)|ensembl:ENSMUST00000032179(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q9QY81|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749 refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:AuekEtMXZWPz0zAGNie485wrKAA10090 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:E158194CBDD7D650|rigid:14bbMZaTNt2ktQkjPZQabyeVrsA false - sufficient binding region:276-393 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80TZ9 uniprotkb:Q15654 intact:EBI-904076|uniprotkb:A2A7T4|ensembl:ENSMUSP00000101307 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:rere_mouse(display_long)|uniprotkb:Rere(gene name)|psi-mi:Rere(display_short)|uniprotkb:Atr2(gene name synonym)|uniprotkb:Kiaa0458(gene name synonym)|uniprotkb:Atrophin-2(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-5796858|imex:IM-16894-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001078961.1|ensembl:ENSMUSG00000039852(gene)|ensembl:ENSMUST00000105682(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0021549"(cerebellum development)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR002951(Atrophin)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884 refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:iiOuYcOw/XS0fkiz5ZGdPONvspk10090 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:5C4BC0C7C4FA704E|rigid:2tUsK6JJLTNxD84zeJY3ckvHZq4 false - sufficient binding region:276-393 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15654 uniprotkb:Q6IRU2 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-5797155|ensembl:ENSMUSP00000003575 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:tpm4_mouse(display_long)|uniprotkb:Tpm4(gene name)|psi-mi:Tpm4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-5797142|imex:IM-16894-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N refseq:NP_001001491.1|ensembl:ENSMUSG00000031799(gene)|ensembl:ENSMUST00000003575(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|reactome:R-MMU-390522|reactome:R-MMU-445355|reactome:R-MMU-9013424 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:lOuj2Qk0dEm9/XVT4Zh75AkMxBM10090 intact-crc:53B54076C3B0ED4B|rigid:+ym+KJBsFcjnboLVRloPMDUTcOg false sufficient binding region:276-393 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15654 uniprotkb:F6SEU4 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-5797569|ensembl:ENSMUSP00000141686 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-5797552|imex:IM-16894-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090 intact-crc:49CA3C64CCFB696E|rigid:7GSEG1XVGWxgEVNAaQIF5rCEN/w false sufficient binding region:276-393 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15654 uniprotkb:Q9QX47 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-643037|uniprotkb:E9PXW2|uniprotkb:E9Q3H8|uniprotkb:E9Q3I0|uniprotkb:E9Q6M4|uniprotkb:E9Q7G2|uniprotkb:E9QAR8|uniprotkb:E9QMT0|uniprotkb:Q811G3|uniprotkb:E3WC91|uniprotkb:Q9CQ12|uniprotkb:Q9CQK6|uniprotkb:Q9QXP5|ensembl:ENSMUSP00000109671 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:son_mouse(display_long)|uniprotkb:Son(gene name)|psi-mi:Son(display_short)|uniprotkb:Nrebp(gene name synonym)|uniprotkb:Negative regulatory element-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-5820441|imex:IM-16894-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N refseq:NP_849211.3|ensembl:ENSMUSG00000022961(gene)|ensembl:ENSMUST00000114037(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000467(D111/G-patch)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032922|interpro:IPR036322|mint:Q9QX47|dip:DIP-49510N - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:jlHOehJSggqYn7vrh90aYVeINNI10090 intact-crc:1D77E2DE912354E1|rigid:wnmWNjUECv+wh0nnSWHJp+Ql7DE false sufficient binding region:276-393 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15654 uniprotkb:O35177 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-2642891|uniprotkb:Q8BJL8|uniprotkb:Q8BMI9|uniprotkb:Q8BM94|uniprotkb:Q8BK90|uniprotkb:Q99KE7|uniprotkb:Q8BL52|ensembl:ENSMUSP00000021794 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:casl_mouse(display_long)|uniprotkb:Casl(gene name synonym)|uniprotkb:CRK-associated substrate-related protein(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 9(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Nedd9(gene name)|psi-mi:Nedd9(display_short) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6049386|imex:IM-16894-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N refseq:NP_001104794.1|refseq:NP_059492.3|ensembl:ENSMUSG00000021365(gene)|ensembl:ENSMUST00000021794(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0040008"(regulation of growth)|go:"GO:0051301"(cell division)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR035746|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|dip:DIP-57058N - - - figure legend:Fig 3B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:M/DE7RwmYizqy+SKJvp0M1f1odY10090 intact-crc:166DA45EA5D553AB|rigid:3ViBkCmxv/aEl3USe3BcyfK8mb8 false sufficient binding region:276-393 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15654 uniprotkb:Q9QY81 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-5796508|uniprotkb:Q3U031|uniprotkb:Q69ZW2|uniprotkb:Q7TQM1|ensembl:ENSMUSP00000032179 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:po210_mouse(display_long)|uniprotkb:Nup210(gene name)|psi-mi:Nup210(display_short)|uniprotkb:Kiaa0906(gene name synonym)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6049393|imex:IM-16894-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N refseq:NP_061285.2|ensembl:ENSMUSG00000030091(gene)|ensembl:ENSMUST00000032179(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q9QY81|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749 - - - figure legend:Fig 3B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:AuekEtMXZWPz0zAGNie485wrKAA10090 intact-crc:B0950C2CAB36A994|rigid:14bbMZaTNt2ktQkjPZQabyeVrsA false sufficient binding region:276-393 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15654 uniprotkb:Q80TZ9 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-904076|uniprotkb:A2A7T4|ensembl:ENSMUSP00000101307 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:rere_mouse(display_long)|uniprotkb:Rere(gene name)|psi-mi:Rere(display_short)|uniprotkb:Atr2(gene name synonym)|uniprotkb:Kiaa0458(gene name synonym)|uniprotkb:Atrophin-2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6049379|imex:IM-16894-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N refseq:NP_001078961.1|ensembl:ENSMUSG00000039852(gene)|ensembl:ENSMUST00000105682(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0021549"(cerebellum development)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR002951(Atrophin)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884 - - - figure legend:Fig 3B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:iiOuYcOw/XS0fkiz5ZGdPONvspk10090 intact-crc:B46270000B82FC84|rigid:2tUsK6JJLTNxD84zeJY3ckvHZq4 false sufficient binding region:276-393 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6IRU2 uniprotkb:Q15654 intact:EBI-5797155|ensembl:ENSMUSP00000003575 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:tpm4_mouse(display_long)|uniprotkb:Tpm4(gene name)|psi-mi:Tpm4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6049372|imex:IM-16894-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001491.1|ensembl:ENSMUSG00000031799(gene)|ensembl:ENSMUST00000003575(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|reactome:R-MMU-390522|reactome:R-MMU-445355|reactome:R-MMU-9013424 refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:Fig 3B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:lOuj2Qk0dEm9/XVT4Zh75AkMxBM10090 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:FB5DCD93A3DB1B1A|rigid:+ym+KJBsFcjnboLVRloPMDUTcOg false - sufficient binding region:276-393 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15654 uniprotkb:F6SEU4 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-5797569|ensembl:ENSMUSP00000141686 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6049400|imex:IM-16894-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442 - - - figure legend:Fig 3B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090 intact-crc:5A67FD18F1200C7C|rigid:7GSEG1XVGWxgEVNAaQIF5rCEN/w false sufficient binding region:276-393 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QX47 uniprotkb:Q15654 intact:EBI-643037|uniprotkb:E9PXW2|uniprotkb:E9Q3H8|uniprotkb:E9Q3I0|uniprotkb:E9Q6M4|uniprotkb:E9Q7G2|uniprotkb:E9QAR8|uniprotkb:E9QMT0|uniprotkb:Q811G3|uniprotkb:E3WC91|uniprotkb:Q9CQ12|uniprotkb:Q9CQK6|uniprotkb:Q9QXP5|ensembl:ENSMUSP00000109671 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:son_mouse(display_long)|uniprotkb:Son(gene name)|psi-mi:Son(display_short)|uniprotkb:Nrebp(gene name synonym)|uniprotkb:Negative regulatory element-binding protein(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6049365|imex:IM-16894-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_849211.3|ensembl:ENSMUSG00000022961(gene)|ensembl:ENSMUST00000114037(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000467(D111/G-patch)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032922|interpro:IPR036322|mint:Q9QX47|dip:DIP-49510N refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:Fig 3B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:jlHOehJSggqYn7vrh90aYVeINNI10090 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:55EFE1BCD39B89EC|rigid:wnmWNjUECv+wh0nnSWHJp+Ql7DE false - sufficient binding region:276-393 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35177 uniprotkb:Q15942 intact:EBI-2642891|uniprotkb:Q8BJL8|uniprotkb:Q8BMI9|uniprotkb:Q8BM94|uniprotkb:Q8BK90|uniprotkb:Q99KE7|uniprotkb:Q8BL52|ensembl:ENSMUSP00000021794 intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7 psi-mi:casl_mouse(display_long)|uniprotkb:Casl(gene name synonym)|uniprotkb:CRK-associated substrate-related protein(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 9(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Nedd9(gene name)|psi-mi:Nedd9(display_short) psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6049407|imex:IM-16894-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001104794.1|refseq:NP_059492.3|ensembl:ENSMUSG00000021365(gene)|ensembl:ENSMUST00000021794(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0040008"(regulation of growth)|go:"GO:0051301"(cell division)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR035746|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|dip:DIP-57058N ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1 - - - figure legend:Fig 3C and 4.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:M/DE7RwmYizqy+SKJvp0M1f1odY10090 rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606 intact-crc:D5ED1D043F541C2C|rigid:V8gckdo7sA54w0jhCswP2m/cZ70 false sufficient binding region:163-315 sufficient binding region:384..384-570..570(IPR001781)|sufficient binding region:384..384-503..503(IPR001781) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QX47 uniprotkb:Q15942 intact:EBI-643037|uniprotkb:E9PXW2|uniprotkb:E9Q3H8|uniprotkb:E9Q3I0|uniprotkb:E9Q6M4|uniprotkb:E9Q7G2|uniprotkb:E9QAR8|uniprotkb:E9QMT0|uniprotkb:Q811G3|uniprotkb:E3WC91|uniprotkb:Q9CQ12|uniprotkb:Q9CQK6|uniprotkb:Q9QXP5|ensembl:ENSMUSP00000109671 intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7 psi-mi:son_mouse(display_long)|uniprotkb:Son(gene name)|psi-mi:Son(display_short)|uniprotkb:Nrebp(gene name synonym)|uniprotkb:Negative regulatory element-binding protein(gene name synonym) psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short) psi-mi:"MI:0018"(two hybrid) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6049414|imex:IM-16894-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_849211.3|ensembl:ENSMUSG00000022961(gene)|ensembl:ENSMUST00000114037(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000467(D111/G-patch)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032922|interpro:IPR036322|mint:Q9QX47|dip:DIP-49510N ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1 - - - figure legend:Fig 3C.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/03/09 2014/10/16 rogid:jlHOehJSggqYn7vrh90aYVeINNI10090 rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606 intact-crc:BE95CC3F7453F404|rigid:VmpsfD0sWUYKxwNzh0FKhV9uUeI false - sufficient binding region:384..384-570..570(IPR001781) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P56945 uniprotkb:Q15942 intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330 intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7 psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym) psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-5820761|imex:IM-16894-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471 ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1 - - - figure legend:Fig 6B and 7.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-imr_90)|taxid:9606(Homo sapiens embryonic fetal lung fibroblast) - 2012/03/09 2014/10/16 rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606 rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606 intact-crc:48647BA72AE7A107|rigid:FpZMz3ryzrg4+xSp271iZMkxZnI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P56945 uniprotkb:Q15654 intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yi et al. (2002) pubmed:11782456|imex:IM-16894 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-5820983|imex:IM-16894-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471 refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:Fig 6C.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-imr_90)|taxid:9606(Homo sapiens embryonic fetal lung fibroblast) - 2012/03/09 2014/10/16 rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:E295BBAACC71A344|rigid:fY1r2hzXucA8NfqeQLx7NEDfDQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)