#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8STE5 uniprotkb:G5EEN3 intact:EBI-6390460|ensemblmetazoa:Y106G6E.5a.1|ensemblmetazoa:Y106G6E.5a.2 intact:EBI-6390483|ensemblmetazoa:C02F4.1.1|ensemblmetazoa:C02F4.1.2 psi-mi:ced12_caeel(display_long)|uniprotkb:ced-12(gene name)|psi-mi:ced-12(display_short)|uniprotkb:Y106G6E.5(orf name) psi-mi:g5een3_caeel(display_long)|uniprotkb:C02F4.1(orf name)|uniprotkb:ced-5(gene name)|psi-mi:ced-5(display_short)|uniprotkb:CELE_C02F4.1(orf name) psi-mi:"MI:0096"(pull down) Wu et al. (2001) pubmed:11703940|imex:IM-18028 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6390528|imex:IM-18028-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y106G6E.5a|ensemblmetazoa:Y106G6E.5a.1(transcript)|ensemblmetazoa:Y106G6E.5a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|ensemblmetazoa:WBGene00000426(gene)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0060097"(cytoskeletal rearrangement involved in phagocytosis, engulfment)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8849471|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR006816(Engulfment and cell motility, ELM)|refseq:NP_492693.1 refseq:NP_501938.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR001452(Src homology-3)|wormbase:C02F4.1|ensemblmetazoa:C02F4.1.1(transcript)|ensemblmetazoa:C02F4.1.2(transcript)|ensemblmetazoa:WBGene00000419(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8980692|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-8849471|interpro:IPR032376|interpro:IPR027357|interpro:IPR035892|interpro:IPR026791|interpro:IPR027007|reactome:R-CEL-6798695|reactome:R-CEL-418885|reactome:R-CEL-983231|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162 - - - figure legend:Figure 3 A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/13 2014/10/16 rogid:aIsYGCpsZ5EuKPyLamW1iL1CPps6239 rogid:VnDRU/8V7erZT8Bd92lWDszhwGY6239 intact-crc:D66F2A51FA37B186|rigid:v4Ck7ywos2uHbuynnmSg0jw7oco false glutathione s tranferase tag:?-?|sufficient binding region:1-396 35s radiolabel:?-?|sufficient binding region:1-1414 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:G5EEN3 uniprotkb:Q8STE5 intact:EBI-6390483|ensemblmetazoa:C02F4.1.1|ensemblmetazoa:C02F4.1.2 intact:EBI-6390460|ensemblmetazoa:Y106G6E.5a.1|ensemblmetazoa:Y106G6E.5a.2 psi-mi:g5een3_caeel(display_long)|uniprotkb:C02F4.1(orf name)|uniprotkb:ced-5(gene name)|psi-mi:ced-5(display_short)|uniprotkb:CELE_C02F4.1(orf name) psi-mi:ced12_caeel(display_long)|uniprotkb:ced-12(gene name)|psi-mi:ced-12(display_short)|uniprotkb:Y106G6E.5(orf name) psi-mi:"MI:0096"(pull down) Wu et al. (2001) pubmed:11703940|imex:IM-18028 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6390457|imex:IM-18028-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501938.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR001452(Src homology-3)|wormbase:C02F4.1|ensemblmetazoa:C02F4.1.1(transcript)|ensemblmetazoa:C02F4.1.2(transcript)|ensemblmetazoa:WBGene00000419(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8980692|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-8849471|interpro:IPR032376|interpro:IPR027357|interpro:IPR035892|interpro:IPR026791|interpro:IPR027007|reactome:R-CEL-6798695|reactome:R-CEL-418885|reactome:R-CEL-983231|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162 wormbase:Y106G6E.5a|ensemblmetazoa:Y106G6E.5a.1(transcript)|ensemblmetazoa:Y106G6E.5a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|ensemblmetazoa:WBGene00000426(gene)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0060097"(cytoskeletal rearrangement involved in phagocytosis, engulfment)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8849471|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR006816(Engulfment and cell motility, ELM)|refseq:NP_492693.1 - - - figure legend:Figure 3 A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/13 2014/10/16 rogid:VnDRU/8V7erZT8Bd92lWDszhwGY6239 rogid:aIsYGCpsZ5EuKPyLamW1iL1CPps6239 intact-crc:BED955CE538FE006|rigid:v4Ck7ywos2uHbuynnmSg0jw7oco false 35s radiolabel:?-?|sufficient binding region:1415-1781 sufficient binding region:397-731|glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:G5EEN3 uniprotkb:Q8STE5 intact:EBI-6390483|ensemblmetazoa:C02F4.1.1|ensemblmetazoa:C02F4.1.2 intact:EBI-6390460|ensemblmetazoa:Y106G6E.5a.1|ensemblmetazoa:Y106G6E.5a.2 psi-mi:g5een3_caeel(display_long)|uniprotkb:C02F4.1(orf name)|uniprotkb:ced-5(gene name)|psi-mi:ced-5(display_short)|uniprotkb:CELE_C02F4.1(orf name) psi-mi:ced12_caeel(display_long)|uniprotkb:ced-12(gene name)|psi-mi:ced-12(display_short)|uniprotkb:Y106G6E.5(orf name) psi-mi:"MI:0018"(two hybrid) Wu et al. (2001) pubmed:11703940|imex:IM-18028 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6390582|imex:IM-18028-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501938.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR001452(Src homology-3)|wormbase:C02F4.1|ensemblmetazoa:C02F4.1.1(transcript)|ensemblmetazoa:C02F4.1.2(transcript)|ensemblmetazoa:WBGene00000419(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8980692|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-8849471|interpro:IPR032376|interpro:IPR027357|interpro:IPR035892|interpro:IPR026791|interpro:IPR027007|reactome:R-CEL-6798695|reactome:R-CEL-418885|reactome:R-CEL-983231|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162 wormbase:Y106G6E.5a|ensemblmetazoa:Y106G6E.5a.1(transcript)|ensemblmetazoa:Y106G6E.5a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|ensemblmetazoa:WBGene00000426(gene)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0060097"(cytoskeletal rearrangement involved in phagocytosis, engulfment)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8849471|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR006816(Engulfment and cell motility, ELM)|refseq:NP_492693.1 - - - figure legend:Figure 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/13 2014/10/16 rogid:VnDRU/8V7erZT8Bd92lWDszhwGY6239 rogid:aIsYGCpsZ5EuKPyLamW1iL1CPps6239 intact-crc:701AA60167C6E501|rigid:v4Ck7ywos2uHbuynnmSg0jw7oco false sufficient binding region:1415-1689 sufficient binding region:397-731 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8STE5 uniprotkb:Q9NHC3 intact:EBI-6390460|ensemblmetazoa:Y106G6E.5a.1|ensemblmetazoa:Y106G6E.5a.2 intact:EBI-6390681|ensemblmetazoa:Y41D4B.13a.1 psi-mi:ced12_caeel(display_long)|uniprotkb:ced-12(gene name)|psi-mi:ced-12(display_short)|uniprotkb:Y106G6E.5(orf name) psi-mi:ced2_caeel(display_long)|uniprotkb:ced-2(gene name)|psi-mi:ced-2(display_short)|uniprotkb:Cell-corpse engulfment protein CED-2(gene name synonym)|uniprotkb:Y41D4B.13(orf name) psi-mi:"MI:0588"(three hybrid) Wu et al. (2001) pubmed:11703940|imex:IM-18028 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6390679|imex:IM-18028-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y106G6E.5a|ensemblmetazoa:Y106G6E.5a.1(transcript)|ensemblmetazoa:Y106G6E.5a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|ensemblmetazoa:WBGene00000426(gene)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0060097"(cytoskeletal rearrangement involved in phagocytosis, engulfment)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8849471|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR006816(Engulfment and cell motility, ELM)|refseq:NP_492693.1 ensemblmetazoa:WBGene00000416(gene)|ensemblmetazoa:Y41D4B.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0012501"(programmed cell death)|go:"GO:0016477"(cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|rcsb pdb:3QWX|rcsb pdb:3QWY|reactome:R-CEL-186763|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-8849471|reactome:R-CEL-912631|refseq:NP_500105.1|wormbase:Y41D4B.13a|dip:DIP-25408N - - - figure legend:Figure 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/13 2014/10/16 rogid:aIsYGCpsZ5EuKPyLamW1iL1CPps6239 rogid:j5cxzcKENbxLxYp0CEUCAXlsmTk6239 intact-crc:50013EA5742D2C19|rigid:uh/H7p9xXPbYRGXSf/NTe9LRjgk false sufficient binding region:397-731 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8STE5 uniprotkb:G5EEN3 intact:EBI-6390460|ensemblmetazoa:Y106G6E.5a.1|ensemblmetazoa:Y106G6E.5a.2 intact:EBI-6390483|ensemblmetazoa:C02F4.1.1|ensemblmetazoa:C02F4.1.2 psi-mi:ced12_caeel(display_long)|uniprotkb:ced-12(gene name)|psi-mi:ced-12(display_short)|uniprotkb:Y106G6E.5(orf name) psi-mi:g5een3_caeel(display_long)|uniprotkb:C02F4.1(orf name)|uniprotkb:ced-5(gene name)|psi-mi:ced-5(display_short)|uniprotkb:CELE_C02F4.1(orf name) psi-mi:"MI:0588"(three hybrid) Wu et al. (2001) pubmed:11703940|imex:IM-18028 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6390679|imex:IM-18028-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y106G6E.5a|ensemblmetazoa:Y106G6E.5a.1(transcript)|ensemblmetazoa:Y106G6E.5a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|ensemblmetazoa:WBGene00000426(gene)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0060097"(cytoskeletal rearrangement involved in phagocytosis, engulfment)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8849471|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR006816(Engulfment and cell motility, ELM)|refseq:NP_492693.1 refseq:NP_501938.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR001452(Src homology-3)|wormbase:C02F4.1|ensemblmetazoa:C02F4.1.1(transcript)|ensemblmetazoa:C02F4.1.2(transcript)|ensemblmetazoa:WBGene00000419(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8980692|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-8849471|interpro:IPR032376|interpro:IPR027357|interpro:IPR035892|interpro:IPR026791|interpro:IPR027007|reactome:R-CEL-6798695|reactome:R-CEL-418885|reactome:R-CEL-983231|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162 - - - figure legend:Figure 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/13 2014/10/16 rogid:aIsYGCpsZ5EuKPyLamW1iL1CPps6239 rogid:VnDRU/8V7erZT8Bd92lWDszhwGY6239 intact-crc:50013EA5742D2C19|rigid:uh/H7p9xXPbYRGXSf/NTe9LRjgk false sufficient binding region:397-731 sufficient binding region:1415-1781 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)