#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P28905	uniprotkb:P28632	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465385|imex:IM-18578-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:7FEFFC359B28AA88	-	figure legend:Fig. 2a, 3c|comment:"Subunit holB (delta') is required for binding of s/u holA (delta) to the rest of the tau complex."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2014/10/16	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333	intact-crc:77C3B59416A0FFA8|rigid:6eygg40CctdSrJFPP1XvK5dPiGg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28905	uniprotkb:P06710-1	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	intact:EBI-6464728	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:p06710-1(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465385|imex:IM-18578-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	intact:EBI-549140(isoform-parent)	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:7FEFFC359B28AA88	isoform-comment:"Produced by full-length translation of the dnaX gene. This isoform is essential, constructs that express only the gamma isoform are not viable (Ref.14)."	figure legend:Fig. 2a, 3c|comment:"Subunit holB (delta') is required for binding of s/u holA (delta) to the rest of the tau complex."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2014/10/16	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	intact-crc:77C3B59416A0FFA8|rigid:6eygg40CctdSrJFPP1XvK5dPiGg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28630	uniprotkb:P28631	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465445|imex:IM-18578-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:87239A678FE16BE2	-	figure legend:Fig. 3b|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau)."|complex-properties:gamma complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2015/06/09	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	intact-crc:63F4EAE7C154E297|rigid:x3MIYCKqE0irmXlfcgCY6ntgSB4	false	-	biotin tag:n-n|necessary binding region:207-334|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28630	uniprotkb:P28905	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465445|imex:IM-18578-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:87239A678FE16BE2	crc64:7FEFFC359B28AA88	figure legend:Fig. 3b|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau)."|complex-properties:gamma complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2015/06/09	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:63F4EAE7C154E297|rigid:x3MIYCKqE0irmXlfcgCY6ntgSB4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28630	uniprotkb:P28632	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465445|imex:IM-18578-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:87239A678FE16BE2	-	figure legend:Fig. 3b|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau)."|complex-properties:gamma complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2015/06/09	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333	intact-crc:63F4EAE7C154E297|rigid:x3MIYCKqE0irmXlfcgCY6ntgSB4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28630	uniprotkb:P06710-2	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	intact:EBI-2604194	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:p06710-2(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465445|imex:IM-18578-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	intact:EBI-549140(isoform-parent)	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:87239A678FE16BE2	isoform-comment:"Formed by programmed ribosomal frameshifting to a premature stop codon in the -1 frame at codon 430, the last residue is thus Glu and not Ser. Mutants which remove the frameshift are viable, suggesting strongly that gamma is not essential for viability (Ref.14)."	figure legend:Fig. 3b|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau)."|complex-properties:gamma complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2015/06/09	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	rogid:JMH64mXrcW06P+gZXBrJZS0hu9w83333	intact-crc:63F4EAE7C154E297|rigid:x3MIYCKqE0irmXlfcgCY6ntgSB4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28905	uniprotkb:P28632	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465466|imex:IM-18578-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:7FEFFC359B28AA88	-	figure legend:Fig. 3d|comment:"Subunit holB (delta') is required for binding of s/u holA (delta) to the rest of the gamma complex."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2015/06/09	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333	intact-crc:053D5BE7A3198DDC|rigid:OpROIQkxuKisps6wqxAqWHxHWRw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28905	uniprotkb:P06710-2	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	intact:EBI-2604194	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:p06710-2(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465466|imex:IM-18578-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	intact:EBI-549140(isoform-parent)	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:7FEFFC359B28AA88	isoform-comment:"Formed by programmed ribosomal frameshifting to a premature stop codon in the -1 frame at codon 430, the last residue is thus Glu and not Ser. Mutants which remove the frameshift are viable, suggesting strongly that gamma is not essential for viability (Ref.14)."	figure legend:Fig. 3d|comment:"Subunit holB (delta') is required for binding of s/u holA (delta) to the rest of the gamma complex."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2015/06/09	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	rogid:JMH64mXrcW06P+gZXBrJZS0hu9w83333	intact-crc:053D5BE7A3198DDC|rigid:OpROIQkxuKisps6wqxAqWHxHWRw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28630	uniprotkb:P28631	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465328|imex:IM-18578-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:87239A678FE16BE2	-	figure legend:Fig. 2b, c, 3a, Table I|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2014/10/16	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	intact-crc:A29A51B0DBBCA132|rigid:trFktjtS766fchoLI2mkkpTmdCw	false	-	necessary binding region:207-334|biotin tag:n-n|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28630	uniprotkb:P28905	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465328|imex:IM-18578-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:87239A678FE16BE2	crc64:7FEFFC359B28AA88	figure legend:Fig. 2b, c, 3a, Table I|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2014/10/16	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:A29A51B0DBBCA132|rigid:trFktjtS766fchoLI2mkkpTmdCw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28630	uniprotkb:P28632	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465328|imex:IM-18578-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:87239A678FE16BE2	-	figure legend:Fig. 2b, c, 3a, Table I|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2014/10/16	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333	intact-crc:A29A51B0DBBCA132|rigid:trFktjtS766fchoLI2mkkpTmdCw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28630	uniprotkb:P06710-1	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	intact:EBI-6464728	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:p06710-1(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465328|imex:IM-18578-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	intact:EBI-549140(isoform-parent)	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	crc64:87239A678FE16BE2	isoform-comment:"Produced by full-length translation of the dnaX gene. This isoform is essential, constructs that express only the gamma isoform are not viable (Ref.14)."	figure legend:Fig. 2b, c, 3a, Table I|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2014/10/16	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	intact-crc:A29A51B0DBBCA132|rigid:trFktjtS766fchoLI2mkkpTmdCw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06710-1	uniprotkb:P28631	intact:EBI-6464728	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	psi-mi:p06710-1(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:"MI:0071"(molecular sieving)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465295|imex:IM-18578-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-549140(isoform-parent)	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	isoform-comment:"Produced by full-length translation of the dnaX gene. This isoform is essential, constructs that express only the gamma isoform are not viable (Ref.14)."	-	figure legend:Fig. 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/18	2014/10/16	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	intact-crc:D80DF2732A0831BA|rigid:7HV1Df0V8lpd9md73YJRsXNgXqM	false	-	his tag:c-c|biotin tag:c-c|necessary binding region:1-334	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28631	uniprotkb:P06710-1	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	intact:EBI-6464728	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:p06710-1(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465546|imex:IM-18578-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	intact:EBI-549140(isoform-parent)	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	-	isoform-comment:"Produced by full-length translation of the dnaX gene. This isoform is essential, constructs that express only the gamma isoform are not viable (Ref.14)."	figure legend:Fig. 4a|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:500.0x10^-9(molar)	2012/12/18	2014/10/16	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	intact-crc:95F8A777455A24F6|rigid:BKqB83gB/pa0PCKfIZ5XWvKGr84	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28631	uniprotkb:P28630	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465546|imex:IM-18578-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	-	crc64:87239A678FE16BE2	figure legend:Fig. 4a|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:500.0x10^-9(molar)	2012/12/18	2014/10/16	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	intact-crc:95F8A777455A24F6|rigid:BKqB83gB/pa0PCKfIZ5XWvKGr84	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28631	uniprotkb:P28905	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465518|imex:IM-18578-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	-	crc64:7FEFFC359B28AA88	figure legend:Fig. 4a|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:110.0x10^-9(molar)	2012/12/18	2014/10/16	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:301662B5D026204F|rigid:trFktjtS766fchoLI2mkkpTmdCw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28631	uniprotkb:P28630	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465518|imex:IM-18578-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	-	crc64:87239A678FE16BE2	figure legend:Fig. 4a|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:110.0x10^-9(molar)	2012/12/18	2014/10/16	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	intact-crc:301662B5D026204F|rigid:trFktjtS766fchoLI2mkkpTmdCw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28631	uniprotkb:P28632	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465518|imex:IM-18578-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	-	-	figure legend:Fig. 4a|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:110.0x10^-9(molar)	2012/12/18	2014/10/16	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333	intact-crc:301662B5D026204F|rigid:trFktjtS766fchoLI2mkkpTmdCw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28631	uniprotkb:P06710-1	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	intact:EBI-6464728	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:p06710-1(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6465518|imex:IM-18578-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	intact:EBI-549140(isoform-parent)	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	-	isoform-comment:"Produced by full-length translation of the dnaX gene. This isoform is essential, constructs that express only the gamma isoform are not viable (Ref.14)."	figure legend:Fig. 4a|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:110.0x10^-9(molar)	2012/12/18	2014/10/16	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	intact-crc:301662B5D026204F|rigid:trFktjtS766fchoLI2mkkpTmdCw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06710-1	uniprotkb:P28631	intact:EBI-6464728	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	psi-mi:p06710-1(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Song et al. (2001)	imex:IM-18578|pubmed:11606586	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6470473|imex:IM-18578-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-549140(isoform-parent)	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	go:"GO:0043846"(DNA polymerase III, clamp loader complex)	isoform-comment:"Produced by full-length translation of the dnaX gene. This isoform is essential, constructs that express only the gamma isoform are not viable (Ref.14)."	-	figure legend:Fig. 4a|comment:"Subunits holA (delta), holC (chi) and holD (psi) stabilise binding of holB (delta') and dnaX (tau).  Table I also shows kinetics for binding of s/u delta' domain III only to the tau complex."|complex-properties:tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:5.0x10^-7(molar)	2012/12/18	2014/10/16	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	intact-crc:DAED49EC608E2271|rigid:7HV1Df0V8lpd9md73YJRsXNgXqM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)