#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UQB8 uniprotkb:Q92558 intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338 intact:EBI-1548747|uniprotkb:E1P5F2|uniprotkb:Q5SZK7|ensembl:ENSP00000352425|ensembl:ENSP00000376365|ensembl:ENSP00000376366|ensembl:ENSP00000376367|ensembl:ENSP00000376368 psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short) psi-mi:wasf1_human(display_long)|uniprotkb:WASF1(gene name)|psi-mi:WASF1(display_short)|uniprotkb:KIAA0269(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:WAVE1(gene name synonym)|uniprotkb:Protein WAVE-1(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Miki et al. (2000) pubmed:11130076|imex:IM-18814|mint:MINT-5213352 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6173703|imex:IM-18814-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape) refseq:NP_001020105.1|refseq:NP_001020106.1|refseq:NP_001020107.1|refseq:NP_003922.1|refseq:XP_011534535.1|refseq:XP_011534536.1|refseq:XP_016866926.1|refseq:XP_016866927.1|refseq:XP_005267260.1|refseq:XP_005267262.1|refseq:XP_005267263.1|refseq:XP_005267264.1|dip:DIP-39391N|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000112290(gene)|ensembl:ENST00000359451(transcript)|ensembl:ENST00000392586(transcript)|ensembl:ENST00000392587(transcript)|ensembl:ENST00000392588(transcript)|ensembl:ENST00000392589(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031209"(SCAR complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0097484"(dendrite extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098939"(dendritic transport of mitochondrion)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q92558|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/07/06 2014/10/16 rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606 rogid:kDHL44b54o8tE3+OR+M2CC6zi/k9606 intact-crc:3C34FD967AF4CF8E|rigid:LonY+Dzv6DvkgzRHgX0PD2GBcB8 false - sufficient binding region:278..278-435..435 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92558 uniprotkb:O94875 intact:EBI-1548747|uniprotkb:E1P5F2|uniprotkb:Q5SZK7|ensembl:ENSP00000352425|ensembl:ENSP00000376365|ensembl:ENSP00000376366|ensembl:ENSP00000376367|ensembl:ENSP00000376368 intact:EBI-311323|intact:EBI-747334|uniprotkb:B7Z1G5|uniprotkb:C9JKV9|uniprotkb:G3XAI0|intact:EBI-2804177|uniprotkb:A6NEK9|uniprotkb:O60592|uniprotkb:O60593|uniprotkb:Q96EX0|uniprotkb:D3DP62|uniprotkb:D3DP63|intact:EBI-28977791|ensembl:ENSP00000284776|uniprotkb:B7Z3X6|uniprotkb:E9PAS5|uniprotkb:E9PAW4|uniprotkb:B3KPQ7|uniprotkb:H7BXR4|uniprotkb:J3KNZ5|intact:EBI-10983198|intact:EBI-10965282 psi-mi:wasf1_human(display_long)|uniprotkb:WASF1(gene name)|psi-mi:WASF1(display_short)|uniprotkb:KIAA0269(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:WAVE1(gene name synonym)|uniprotkb:Protein WAVE-1(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 1(gene name synonym) psi-mi:srbs2_human(display_long)|uniprotkb:SORBS2(gene name)|psi-mi:SORBS2(display_short)|uniprotkb:ARGBP2(gene name synonym)|uniprotkb:KIAA0777(gene name synonym)|uniprotkb:Arg/Abl-interacting protein 2(gene name synonym)|uniprotkb:Sorbin(gene name synonym)|uniprotkb:Arg-binding protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Miki et al. (2000) pubmed:11130076|imex:IM-18814|mint:MINT-5213352 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6173706|imex:IM-18814-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020105.1|refseq:NP_001020106.1|refseq:NP_001020107.1|refseq:NP_003922.1|refseq:XP_011534535.1|refseq:XP_011534536.1|refseq:XP_016866926.1|refseq:XP_016866927.1|refseq:XP_005267260.1|refseq:XP_005267262.1|refseq:XP_005267263.1|refseq:XP_005267264.1|dip:DIP-39391N|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000112290(gene)|ensembl:ENST00000359451(transcript)|ensembl:ENST00000392586(transcript)|ensembl:ENST00000392587(transcript)|ensembl:ENST00000392588(transcript)|ensembl:ENST00000392589(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031209"(SCAR complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0097484"(dendrite extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098939"(dendritic transport of mitochondrion)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q92558|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149 ensembl:ENSP00000284776|ensembl:ENST00000319471|ensembl:ENSP00000322182|ensembl:ENST00000355634|ensembl:ENSP00000347852|ensembl:ENST00000393528|ensembl:ENSP00000377162|ensembl:ENST00000418609|ensembl:ENSP00000397482|ensembl:ENST00000437304|ensembl:ENSP00000396008|ensembl:ENST00000448662|ensembl:ENSP00000409158|ensembl:ENST00000449407|ensembl:ENSP00000397262|ensembl:ENSG00000154556(gene)|ensembl:ENST00000284776(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028506|interpro:IPR036028|mint:O94875|rcsb pdb:5VEI|refseq:NP_001139142.1|refseq:NP_001139144.1|refseq:NP_001139145.1|refseq:NP_066547.1|refseq:NP_001139146.1|refseq:NP_001139143.1|refseq:NP_001257700.1|refseq:NP_003594.3|refseq:XP_005263369.1|refseq:XP_006714453.1|refseq:XP_016864260.1|dip:DIP-31634N - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/07/06 2014/10/16 rogid:kDHL44b54o8tE3+OR+M2CC6zi/k9606 rogid:ficlNf23am8NpwQVRUKXeVUJTsQ9606 intact-crc:7F9526BB1B2E67EB|rigid:uXYwIjKGU30EFwwEZ400UyHZ/iQ false sufficient binding region:278..278-435..435 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q91YD9 uniprotkb:P06241 intact:EBI-642417|ensembl:ENSMUSP00000031695 intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656 psi-mi:wasl_mouse(display_long)|uniprotkb:Wasl(gene name)|psi-mi:Wasl(display_short) psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym) psi-mi:"MI:0096"(pull down) Miki et al. (2000) pubmed:11130076|imex:IM-18814|mint:MINT-5213352 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6174038|imex:IM-18814-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082735.2|ensembl:ENSMUSG00000029684(gene)|ensembl:ENSMUST00000031695(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045010"(actin nucleation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:Q91YD9|rcsb pdb:3M3N|rcsb pdb:6UHC|dip:DIP-29788N refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439 - - - figure legend:Fig 1b.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/06 2014/10/16 rogid:TXI8wfugOptN0kVS3yEJxaM4uq810090 rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606 intact-crc:29FE591D52AC5618|rigid:mUvqtczBdDCKWiNGRV5cE4/sKro false - sufficient binding region:82-143(IPR001452)|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UQB8-4 uniprotkb:Q9Y6W5 intact:EBI-6174091|ensembl:ENSP00000315685 intact:EBI-4290615|uniprotkb:O60794|uniprotkb:Q9UDY7|intact:EBI-28973998|ensembl:ENSP00000483313|uniprotkb:B4DZN0 psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym) psi-mi:wasf2_human(display_long)|uniprotkb:WASF2(gene name)|psi-mi:WASF2(display_short)|uniprotkb:WAVE2(gene name synonym)|uniprotkb:Protein WAVE-2(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Miki et al. (2000) pubmed:11130076|imex:IM-18814|mint:MINT-5213352 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6174136|imex:IM-18814-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent) refseq:NP_008921.1|ensembl:ENST00000536657|ensembl:ENSP00000439883|ensembl:ENSP00000483313|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q9Y6W5|rcsb pdb:2A40|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|ensembl:ENSG00000158195(gene)|ensembl:ENST00000618852(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031209"(SCAR complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|refseq:NP_001188333.1|dip:DIP-41817N - - - figure legend:Fig 1d, Suppl fig 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/06 2014/10/16 rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606 rogid:lRPT4syjPdKz2JoqWQQm3xw4hWc9606 intact-crc:0C1B191FFA5F0119|rigid:kcculYxq4F+f9h0RlSfaBTNk7NU false - sufficient binding region:356-372|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y6W5 uniprotkb:Q9UQB8-4 intact:EBI-4290615|uniprotkb:O60794|uniprotkb:Q9UDY7|intact:EBI-28973998|ensembl:ENSP00000483313|uniprotkb:B4DZN0 intact:EBI-6174091|ensembl:ENSP00000315685 psi-mi:wasf2_human(display_long)|uniprotkb:WASF2(gene name)|psi-mi:WASF2(display_short)|uniprotkb:WAVE2(gene name synonym)|uniprotkb:Protein WAVE-2(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 2(gene name synonym) psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Miki et al. (2000) pubmed:11130076|imex:IM-18814|mint:MINT-5213352 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6174162|imex:IM-18814-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008921.1|ensembl:ENST00000536657|ensembl:ENSP00000439883|ensembl:ENSP00000483313|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q9Y6W5|rcsb pdb:2A40|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|ensembl:ENSG00000158195(gene)|ensembl:ENST00000618852(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031209"(SCAR complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|refseq:NP_001188333.1|dip:DIP-41817N ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent) - - - figure legend:"Fig 2c (top)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/06 2014/10/16 rogid:lRPT4syjPdKz2JoqWQQm3xw4hWc9606 rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606 intact-crc:E3CAE59288692681|rigid:kcculYxq4F+f9h0RlSfaBTNk7NU false sufficient binding region:273-402|myc tag:?-? glutathione s tranferase tag:?-?|sufficient binding region:364-521(IPR001452) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UQB8-4 uniprotkb:Q9Y6W5 intact:EBI-6174091|ensembl:ENSP00000315685 intact:EBI-4290615|uniprotkb:O60794|uniprotkb:Q9UDY7|intact:EBI-28973998|ensembl:ENSP00000483313|uniprotkb:B4DZN0 psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym) psi-mi:wasf2_human(display_long)|uniprotkb:WASF2(gene name)|psi-mi:WASF2(display_short)|uniprotkb:WAVE2(gene name synonym)|uniprotkb:Protein WAVE-2(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 2(gene name synonym) psi-mi:"MI:0047"(far western blotting) Miki et al. (2000) pubmed:11130076|imex:IM-18814|mint:MINT-5213352 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6174075|imex:IM-18814-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent) refseq:NP_008921.1|ensembl:ENST00000536657|ensembl:ENSP00000439883|ensembl:ENSP00000483313|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q9Y6W5|rcsb pdb:2A40|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|ensembl:ENSG00000158195(gene)|ensembl:ENST00000618852(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031209"(SCAR complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|refseq:NP_001188333.1|dip:DIP-41817N - - - figure legend:Fig 1c.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/06 2014/10/16 rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606 rogid:lRPT4syjPdKz2JoqWQQm3xw4hWc9606 intact-crc:1A7A12D07F42E485|rigid:kcculYxq4F+f9h0RlSfaBTNk7NU false glutathione s tranferase tag:?-?|sufficient binding region:364-521(IPR001452) flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UQB8-4 uniprotkb:Q9Y6W5 intact:EBI-6174091|ensembl:ENSP00000315685 intact:EBI-4290615|uniprotkb:O60794|uniprotkb:Q9UDY7|intact:EBI-28973998|ensembl:ENSP00000483313|uniprotkb:B4DZN0 psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym) psi-mi:wasf2_human(display_long)|uniprotkb:WASF2(gene name)|psi-mi:WASF2(display_short)|uniprotkb:WAVE2(gene name synonym)|uniprotkb:Protein WAVE-2(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Miki et al. (2000) pubmed:11130076|imex:IM-18814|mint:MINT-5213352 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6174151|imex:IM-18814-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent) refseq:NP_008921.1|ensembl:ENST00000536657|ensembl:ENSP00000439883|ensembl:ENSP00000483313|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q9Y6W5|rcsb pdb:2A40|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|ensembl:ENSG00000158195(gene)|ensembl:ENST00000618852(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031209"(SCAR complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|refseq:NP_001188333.1|dip:DIP-41817N - - - figure legend:Fig 2a.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/07/06 2014/10/16 rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606 rogid:lRPT4syjPdKz2JoqWQQm3xw4hWc9606 intact-crc:7D82727C60C3D346|rigid:kcculYxq4F+f9h0RlSfaBTNk7NU false necessary binding region:364-521|myc tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y6W5 uniprotkb:Q9UQB8-4 intact:EBI-4290615|uniprotkb:O60794|uniprotkb:Q9UDY7|intact:EBI-28973998|ensembl:ENSP00000483313|uniprotkb:B4DZN0 intact:EBI-6174091|ensembl:ENSP00000315685 psi-mi:wasf2_human(display_long)|uniprotkb:WASF2(gene name)|psi-mi:WASF2(display_short)|uniprotkb:WAVE2(gene name synonym)|uniprotkb:Protein WAVE-2(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 2(gene name synonym) psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Miki et al. (2000) pubmed:11130076|imex:IM-18814|mint:MINT-5213352 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6174182|imex:IM-18814-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008921.1|ensembl:ENST00000536657|ensembl:ENSP00000439883|ensembl:ENSP00000483313|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q9Y6W5|rcsb pdb:2A40|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|ensembl:ENSG00000158195(gene)|ensembl:ENST00000618852(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031209"(SCAR complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|refseq:NP_001188333.1|dip:DIP-41817N ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent) - - - figure legend:Suppl. fig 1b.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/06 2014/10/16 rogid:lRPT4syjPdKz2JoqWQQm3xw4hWc9606 rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606 intact-crc:50F3D9E6DD526D96|rigid:kcculYxq4F+f9h0RlSfaBTNk7NU false flag tag:?-? sufficient binding region:364-521(IPR001452)|glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)