#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8N8S7	uniprotkb:Q15942	intact:EBI-2834410|uniprotkb:Q5VTQ9|uniprotkb:Q9UFB8|uniprotkb:Q9NVF3|uniprotkb:Q502W5|uniprotkb:Q5T5M7|uniprotkb:Q5VTR0|uniprotkb:D0PQI2|ensembl:ENSP00000355809	intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	psi-mi:enah_human(display_long)|uniprotkb:ENAH(gene name)|psi-mi:ENAH(display_short)|uniprotkb:MENA(gene name synonym)	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Drees et al. (2000)	pubmed:10801818|imex:IM-16988	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6083026|imex:IM-16988-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008493.1|refseq:NP_060682.2|ensembl:ENSG00000154380(gene)|ensembl:ENST00000366844(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|mint:Q8N8S7|rcsb pdb:2HO2|rcsb pdb:2IYB|rcsb pdb:2XQN|rcsb pdb:4MY6|rcsb pdb:5N91|rcsb pdb:5N9C|rcsb pdb:5N9P|rcsb pdb:5NAJ|rcsb pdb:5NBF|rcsb pdb:5NBX|go:"GO:0005925"(focal adhesion)|rcsb pdb:5NC2|rcsb pdb:5NC7|rcsb pdb:5NCF|rcsb pdb:5NCG|rcsb pdb:5NCP|rcsb pdb:5ND0|rcsb pdb:5NDU|rcsb pdb:5NEG|rcsb pdb:6RCF|rcsb pdb:6RCJ|rcsb pdb:6RD2|rcsb pdb:6XVT|rcsb pdb:6XXR|rcsb pdb:7A5M|rcsb pdb:7AKI|reactome:R-HSA-202433|reactome:R-HSA-376176	ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1	-	-	-	figure legend:Fig 3B.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/04/10	2014/10/16	rogid:FxcMlDgO3bbl9NRD/z+fDOcdLic9606	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	intact-crc:32599CA4A0823224|rigid:IW4LW6MdXJR9qTaTD/fWNsm31MU	false	-	mutation decreasing interaction:71-71|mutation decreasing interaction:71-71,104-104,93-93|mutation decreasing interaction:93-93|mutation decreasing interaction:71-71,93-93|sufficient binding region:1-380|myc tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03173	uniprotkb:Q15942	intact:EBI-6083294|uniprotkb:P70430|uniprotkb:P70431|uniprotkb:P70432|uniprotkb:P70433|uniprotkb:Q5D053	intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	psi-mi:enah_mouse(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym)	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:"MI:0047"(far western blotting)	Drees et al. (2000)	pubmed:10801818|imex:IM-16988	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6083292|imex:IM-16988-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q03173|refseq:NP_001076590.1|dip:DIP-29359N|go:"GO:0001725"(stress fiber)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|rcsb pdb:1EVH|rcsb pdb:4CC3|reactome:R-MMU-376176	ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1	-	-	-	figure legend:Fig 1.|comment:A library of 187 overlapping synthetic peptides spanning the complete sequence human zyxin was  immobilized on the SPOTs membrane and probed by the bait.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/10	2014/10/16	rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	intact-crc:3F4D0CE277560EA4|rigid:lz2VGiYVI9vpwlESqBrZGy123o0	false	sufficient binding region:6-170(IPR000697)|glutathione s tranferase tag:?-?|32p radiolabel:?-?	sufficient binding region:67-81|mutation disrupting interaction:71-71	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)