#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P98164 uniprotkb:P98082 intact:EBI-947916|uniprotkb:O00711|uniprotkb:Q16215|ensembl:ENSP00000496870 intact:EBI-1171238|uniprotkb:Q13598|uniprotkb:Q9BTY0|uniprotkb:Q9UK04|uniprotkb:A6NES5|intact:EBI-28967074|ensembl:ENSP00000313391 psi-mi:lrp2_human(display_long)|uniprotkb:Megalin(gene name synonym)|uniprotkb:Glycoprotein 330(gene name synonym)|uniprotkb:LRP2(gene name)|psi-mi:LRP2(display_short) psi-mi:dab2_human(display_long)|uniprotkb:DAB2(gene name)|psi-mi:DAB2(display_short)|uniprotkb:DOC2(gene name synonym)|uniprotkb:Differentially-expressed protein 2(gene name synonym)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Oleinikov et al. (2000) pubmed:10769163 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6306637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004516.2|ensembl:ENSG00000081479(gene)|ensembl:ENST00000649046(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030900"(forebrain development)|go:"GO:0031526"(brush border membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0035904"(aorta development)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0042562"(hormone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0044321"(response to leptin)|go:"GO:0045056"(transcytosis)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060068"(vagina development)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0140058"(neuron projection arborization)|go:"GO:0140318"(protein transporter activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904447"(folate import across plasma membrane)|go:"GO:1905167"(positive regulation of lysosomal protein catabolic process)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR019825|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|rcsb pdb:2M0P|reactome:R-HSA-196791|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-975634 ensembl:ENSP00000313391|ensembl:ENST00000339788|ensembl:ENSP00000345508|ensembl:ENST00000509337|ensembl:ENSP00000426245|ensembl:ENST00000545653|ensembl:ENSP00000439919|refseq:NP_001334.2|refseq:NP_001231800.1|ensembl:ENSG00000153071(gene)|ensembl:ENST00000320816(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2LSW|rcsb pdb:6O5O|rcsb pdb:6OVF|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-45617N - - - figure legend:1 and 5|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/09/25 2014/10/16 rogid:JDlI4t/EC/jeCde5RYJqidr4lfg9606 rogid:DLo0+0XUrWaKw1ycCrIefyVK/YM9606 intact-crc:568409BA431F3DB3|rigid:CLQVqrdXVeq/s1g/9g4SblELqLw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P98082 uniprotkb:P98164 intact:EBI-1171238|uniprotkb:Q13598|uniprotkb:Q9BTY0|uniprotkb:Q9UK04|uniprotkb:A6NES5|intact:EBI-28967074|ensembl:ENSP00000313391 intact:EBI-947916|uniprotkb:O00711|uniprotkb:Q16215|ensembl:ENSP00000496870 psi-mi:dab2_human(display_long)|uniprotkb:DAB2(gene name)|psi-mi:DAB2(display_short)|uniprotkb:DOC2(gene name synonym)|uniprotkb:Differentially-expressed protein 2(gene name synonym)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym) psi-mi:lrp2_human(display_long)|uniprotkb:Megalin(gene name synonym)|uniprotkb:Glycoprotein 330(gene name synonym)|uniprotkb:LRP2(gene name)|psi-mi:LRP2(display_short) psi-mi:"MI:0018"(two hybrid) Oleinikov et al. (2000) pubmed:10769163 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6306626 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000313391|ensembl:ENST00000339788|ensembl:ENSP00000345508|ensembl:ENST00000509337|ensembl:ENSP00000426245|ensembl:ENST00000545653|ensembl:ENSP00000439919|refseq:NP_001334.2|refseq:NP_001231800.1|ensembl:ENSG00000153071(gene)|ensembl:ENST00000320816(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2LSW|rcsb pdb:6O5O|rcsb pdb:6OVF|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-45617N refseq:NP_004516.2|ensembl:ENSG00000081479(gene)|ensembl:ENST00000649046(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030900"(forebrain development)|go:"GO:0031526"(brush border membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0035904"(aorta development)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0042562"(hormone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0044321"(response to leptin)|go:"GO:0045056"(transcytosis)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060068"(vagina development)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0140058"(neuron projection arborization)|go:"GO:0140318"(protein transporter activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904447"(folate import across plasma membrane)|go:"GO:1905167"(positive regulation of lysosomal protein catabolic process)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR019825|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|rcsb pdb:2M0P|reactome:R-HSA-196791|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-975634 - - - figure legend:no figure|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/09/25 2014/10/16 rogid:DLo0+0XUrWaKw1ycCrIefyVK/YM9606 rogid:JDlI4t/EC/jeCde5RYJqidr4lfg9606 intact-crc:63D00AE0806179DD|rigid:CLQVqrdXVeq/s1g/9g4SblELqLw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P98158 uniprotkb:P98082 intact:EBI-6306650 intact:EBI-1171238|uniprotkb:Q13598|uniprotkb:Q9BTY0|uniprotkb:Q9UK04|uniprotkb:A6NES5|intact:EBI-28967074|ensembl:ENSP00000313391 psi-mi:lrp2_rat(display_long)|uniprotkb:Lrp2(gene name)|psi-mi:Lrp2(display_short)|uniprotkb:Glycoprotein 330(gene name synonym)|uniprotkb:Megalin(gene name synonym) psi-mi:dab2_human(display_long)|uniprotkb:DAB2(gene name)|psi-mi:DAB2(display_short)|uniprotkb:DOC2(gene name synonym)|uniprotkb:Differentially-expressed protein 2(gene name synonym)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym) psi-mi:"MI:0096"(pull down) Oleinikov et al. (2000) pubmed:10769163 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6306648 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006766"(vitamin metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0020028"(endocytic hemoglobin import into cell)|go:"GO:0030001"(metal ion transport)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031526"(brush border membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033280"(response to vitamin D)|go:"GO:0035904"(aorta development)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044321"(response to leptin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046879"(hormone secretion)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060068"(vagina development)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061642"(chemoattraction of axon)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0140058"(neuron projection arborization)|go:"GO:0140077"(positive regulation of lipoprotein transport)|go:"GO:0140318"(protein transporter activity)|go:"GO:1904447"(folate import across plasma membrane)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|rcsb pdb:2I1P|rcsb pdb:3V2O|rcsb pdb:3V2X|rgd:68407|refseq:NP_110454.1|dip:DIP-44866N|reactome:R-RNO-196791|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-975634 ensembl:ENSP00000313391|ensembl:ENST00000339788|ensembl:ENSP00000345508|ensembl:ENST00000509337|ensembl:ENSP00000426245|ensembl:ENST00000545653|ensembl:ENSP00000439919|refseq:NP_001334.2|refseq:NP_001231800.1|ensembl:ENSG00000153071(gene)|ensembl:ENST00000320816(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2LSW|rcsb pdb:6O5O|rcsb pdb:6OVF|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-45617N - - - figure legend:2|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/25 2014/10/16 rogid:ewHsW5Lja6xqFQ9T6manhy6X+fE10116 rogid:DLo0+0XUrWaKw1ycCrIefyVK/YM9606 intact-crc:F837C2290A4B2895|rigid:Xm81jPsQjSJyTfXi3wiSwZ2Vt1Y false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88797 uniprotkb:P98158 intact:EBI-6109302|uniprotkb:O55048|uniprotkb:O55049|uniprotkb:O55050|uniprotkb:O55051|uniprotkb:O88798|uniprotkb:Q4QRA2 intact:EBI-6306650 psi-mi:dab2_rat(display_long)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym)|uniprotkb:Dab2(gene name)|psi-mi:Dab2(display_short)|uniprotkb:Doc2(gene name synonym)|uniprotkb:C9(gene name synonym)|uniprotkb:Mitogen-responsive phosphoprotein(gene name synonym) psi-mi:lrp2_rat(display_long)|uniprotkb:Lrp2(gene name)|psi-mi:Lrp2(display_short)|uniprotkb:Glycoprotein 330(gene name synonym)|uniprotkb:Megalin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Oleinikov et al. (2000) pubmed:10769163 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6306714 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032349"(positive regulation of aldosterone biosynthetic process)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902074"(response to salt)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000298"(regulation of Rho-dependent protein serine/threonine kinase activity)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000860"(positive regulation of aldosterone secretion)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:3H8D|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005178"(integrin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007588"(excretion)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030276"(clathrin binding)|rgd:621007|refseq:NP_077073.1|dip:DIP-60713N|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-8856825|reactome:R-RNO-8856828 go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006766"(vitamin metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0020028"(endocytic hemoglobin import into cell)|go:"GO:0030001"(metal ion transport)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031526"(brush border membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033280"(response to vitamin D)|go:"GO:0035904"(aorta development)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044321"(response to leptin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046879"(hormone secretion)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060068"(vagina development)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061642"(chemoattraction of axon)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0140058"(neuron projection arborization)|go:"GO:0140077"(positive regulation of lipoprotein transport)|go:"GO:0140318"(protein transporter activity)|go:"GO:1904447"(folate import across plasma membrane)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|rcsb pdb:2I1P|rcsb pdb:3V2O|rcsb pdb:3V2X|rgd:68407|refseq:NP_110454.1|dip:DIP-44866N|reactome:R-RNO-196791|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-975634 - - - figure legend:3|curation depth:mimix curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2012/09/25 2014/10/16 rogid:mbuTEczmft0j0LYuKPkW5PzDf8c10116 rogid:ewHsW5Lja6xqFQ9T6manhy6X+fE10116 intact-crc:A56DD3CF60F2B39D|rigid:86MZAMlP8guihg+a4y1vcZn6MVE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88797 uniprotkb:P98158 intact:EBI-6109302|uniprotkb:O55048|uniprotkb:O55049|uniprotkb:O55050|uniprotkb:O55051|uniprotkb:O88798|uniprotkb:Q4QRA2 intact:EBI-6306650 psi-mi:dab2_rat(display_long)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym)|uniprotkb:Dab2(gene name)|psi-mi:Dab2(display_short)|uniprotkb:Doc2(gene name synonym)|uniprotkb:C9(gene name synonym)|uniprotkb:Mitogen-responsive phosphoprotein(gene name synonym) psi-mi:lrp2_rat(display_long)|uniprotkb:Lrp2(gene name)|psi-mi:Lrp2(display_short)|uniprotkb:Glycoprotein 330(gene name synonym)|uniprotkb:Megalin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Oleinikov et al. (2000) pubmed:10769163 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6306718 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032349"(positive regulation of aldosterone biosynthetic process)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902074"(response to salt)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000298"(regulation of Rho-dependent protein serine/threonine kinase activity)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000860"(positive regulation of aldosterone secretion)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:3H8D|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005178"(integrin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007588"(excretion)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030276"(clathrin binding)|rgd:621007|refseq:NP_077073.1|dip:DIP-60713N|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-8856825|reactome:R-RNO-8856828 go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006766"(vitamin metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0020028"(endocytic hemoglobin import into cell)|go:"GO:0030001"(metal ion transport)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031526"(brush border membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033280"(response to vitamin D)|go:"GO:0035904"(aorta development)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044321"(response to leptin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046879"(hormone secretion)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060068"(vagina development)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061642"(chemoattraction of axon)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0140058"(neuron projection arborization)|go:"GO:0140077"(positive regulation of lipoprotein transport)|go:"GO:0140318"(protein transporter activity)|go:"GO:1904447"(folate import across plasma membrane)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|rcsb pdb:2I1P|rcsb pdb:3V2O|rcsb pdb:3V2X|rgd:68407|refseq:NP_110454.1|dip:DIP-44866N|reactome:R-RNO-196791|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-975634 - - - figure legend:3|curation depth:mimix curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2012/09/25 2014/10/16 rogid:mbuTEczmft0j0LYuKPkW5PzDf8c10116 rogid:ewHsW5Lja6xqFQ9T6manhy6X+fE10116 intact-crc:4C4465B9BCFD7E77|rigid:86MZAMlP8guihg+a4y1vcZn6MVE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)