#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P34901 uniprotkb:P04937 intact:EBI-1173182|ensembl:ENSRNOP00000019386 intact:EBI-6127274|uniprotkb:Q6LDX9 psi-mi:sdc4_rat(display_long)|uniprotkb:Sdc4(gene name)|psi-mi:Sdc4(display_short)|uniprotkb:Synd4(gene name synonym)|uniprotkb:Ryudocan core protein(gene name synonym) psi-mi:finc_rat(display_long)|uniprotkb:Fn1(gene name)|psi-mi:Fn1(display_short) psi-mi:"MI:0030"(cross-linking study) Woods et al. (2000) pubmed:10640397|imex:IM-17325 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6115146|imex:IM-17325-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000014297(gene)|ensembl:ENSRNOT00000019386(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0001843"(neural tube closure)|go:"GO:0009986"(cell surface)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0042060"(wound healing)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0045121"(membrane raft)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|rcsb pdb:5A2P|rcsb pdb:5G1D|reactome:R-RNO-1971475|reactome:R-RNO-2022928|reactome:R-RNO-2024096|reactome:R-RNO-202733|reactome:R-RNO-3000170|reactome:R-RNO-975634|rgd:3650|refseq:NP_036781.1 mint:P04937|rgd:2624|interpro:IPR000083(Fibronectin, type I)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0001775"(cell activation)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010039"(response to iron ion)|go:"GO:0010193"(response to ozone)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904646"(cellular response to amyloid-beta)|reactome:R-RNO-114608|reactome:R-RNO-1474228|reactome:R-RNO-1474244|reactome:R-RNO-1566977|reactome:R-RNO-202733|reactome:R-RNO-2129379|reactome:R-RNO-216083|reactome:R-RNO-3000170|reactome:R-RNO-3000171|reactome:R-RNO-3000178|reactome:R-RNO-354192|reactome:R-RNO-354194|reactome:R-RNO-372708|reactome:R-RNO-381426|reactome:R-RNO-5674135|reactome:R-RNO-8874081|reactome:R-RNO-8957275 - - - figure legend:"Fig 5a (lane 3)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/02 2014/10/16 rogid:3gbcHld6lSjVWpQQN5A+7PtnX6U10116 rogid:eN6XoJTeRD0TcgGI43GcJY4zzXk10116 intact-crc:D46596A91C8802E4|rigid:4ueqwAekVL6JbyTu8lRr08mgviA false - sufficient binding region:1631-1991|his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P04937 uniprotkb:P34901 intact:EBI-6127274|uniprotkb:Q6LDX9 intact:EBI-1173182|ensembl:ENSRNOP00000019386 psi-mi:finc_rat(display_long)|uniprotkb:Fn1(gene name)|psi-mi:Fn1(display_short) psi-mi:sdc4_rat(display_long)|uniprotkb:Sdc4(gene name)|psi-mi:Sdc4(display_short)|uniprotkb:Synd4(gene name synonym)|uniprotkb:Ryudocan core protein(gene name synonym) psi-mi:"MI:0807"(comigration in gel electrophoresis) Woods et al. (2000) pubmed:10640397|imex:IM-17325 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6115186|imex:IM-17325-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P04937|rgd:2624|interpro:IPR000083(Fibronectin, type I)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0001775"(cell activation)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010039"(response to iron ion)|go:"GO:0010193"(response to ozone)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904646"(cellular response to amyloid-beta)|reactome:R-RNO-114608|reactome:R-RNO-1474228|reactome:R-RNO-1474244|reactome:R-RNO-1566977|reactome:R-RNO-202733|reactome:R-RNO-2129379|reactome:R-RNO-216083|reactome:R-RNO-3000170|reactome:R-RNO-3000171|reactome:R-RNO-3000178|reactome:R-RNO-354192|reactome:R-RNO-354194|reactome:R-RNO-372708|reactome:R-RNO-381426|reactome:R-RNO-5674135|reactome:R-RNO-8874081|reactome:R-RNO-8957275 ensembl:ENSRNOG00000014297(gene)|ensembl:ENSRNOT00000019386(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0001843"(neural tube closure)|go:"GO:0009986"(cell surface)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0042060"(wound healing)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0045121"(membrane raft)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|rcsb pdb:5A2P|rcsb pdb:5G1D|reactome:R-RNO-1971475|reactome:R-RNO-2022928|reactome:R-RNO-2024096|reactome:R-RNO-202733|reactome:R-RNO-3000170|reactome:R-RNO-975634|rgd:3650|refseq:NP_036781.1 - - - figure legend:Fig 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/02 2014/10/16 rogid:eN6XoJTeRD0TcgGI43GcJY4zzXk10116 rogid:3gbcHld6lSjVWpQQN5A+7PtnX6U10116 intact-crc:0DEEEA88177C7CEA|rigid:4ueqwAekVL6JbyTu8lRr08mgviA false sufficient binding region:1631-1991|his tag:n-n 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)