#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A7MB62 uniprotkb:Q95107 intact:EBI-6162748|ensembl:ENSBTAP00000012872 intact:EBI-6162776|ensembl:ENSBTAP00000006094|ensembl:ENSBTAP00000074401 psi-mi:arp2_bovin(display_long)|uniprotkb:ACTR2(gene name)|psi-mi:ACTR2(display_short)|uniprotkb:ARP2(gene name synonym)|uniprotkb:Actin-like protein 2(gene name synonym) psi-mi:wasl_bovin(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short) psi-mi:"MI:0096"(pull down) Rohatgi et al. (1999) pubmed:10219243|imex:IM-18810 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6162634|imex:IM-18810-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095683.1|dip:DIP-29789N|ensembl:ENSBTAG00000009761(gene)|ensembl:ENSBTAT00000012872(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1K8K|rcsb pdb:1TYQ|rcsb pdb:1U2V|rcsb pdb:2P9I|rcsb pdb:2P9K|rcsb pdb:2P9L|rcsb pdb:2P9N|rcsb pdb:2P9P|rcsb pdb:2P9S|rcsb pdb:2P9U|rcsb pdb:3DXK|rcsb pdb:3DXM|rcsb pdb:3RSE|rcsb pdb:3UKR|rcsb pdb:3UKU|rcsb pdb:3ULE|rcsb pdb:4JD2|rcsb pdb:4XEI|rcsb pdb:4XF2|rcsb pdb:6DEC refseq:NP_776644.1|ensembl:ENSBTAG00000004643(gene)|ensembl:ENSBTAT00000006094(transcript)|ensembl:ENSBTAT00000074672(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0009617"(response to bacterium)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030478"(actin cap)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936 - - - figure legend:Fig 3B.|comment:"The interaction was demonstrated between N-WASP and the Arp 2/3 complex (composed of Arp3, Arp2, p41-Arc, p34-Arc, p21-Arc, p20-Arc, p16-Arc)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/22 2014/10/16 rogid:URQsZpIsMtsFZAnpLYDDvgKcPqA9913 rogid:v4dTFUA1oNYafAFrfkpzj5jWSPY9913 intact-crc:81E84D652DC5645F|rigid:iv0DZgpIHM0ssZ5d4aYlKHvakc4 false - glutathione s tranferase tag:?-?|sufficient binding region:450-505 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)