#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q99952	uniprotkb:O43586	intact:EBI-1384210|uniprotkb:Q53P42|intact:EBI-3959579|uniprotkb:B4E1E6|ensembl:ENSP00000175756	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	psi-mi:ptn18_human(display_long)|uniprotkb:Brain-derived phosphatase(gene name synonym)|uniprotkb:PTPN18(gene name)|psi-mi:PTPN18(display_short)|uniprotkb:BDP1(gene name synonym)	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dowbenko et al. (1998)	mint:MINT-8254333|doi:10.1074/jbc.273.2.989|pubmed:9422760	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8674047|mint:MINT-8254395	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055184.2|refseq:NP_001135842.1|ensembl:ENSG00000072135(gene)|ensembl:ENST00000175756(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:1901185"(negative regulation of ERBB signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:Q99952|rcsb pdb:2OC3|rcsb pdb:4GFU|rcsb pdb:4GFV|rcsb pdb:4NND|reactome:R-HSA-8863795|reactome:R-HSA-9008059|mint:MINT-8254397(identity)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|mint:MINT-8254398(identity)	-	-	-	figure legend:F1|comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/10/20	2014/10/16	rogid:xRrifp9kOwi0SLtlIFtSjiv4qN89606	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	intact-crc:8EF6592A4403E23D|rigid:q6hX9PGwpjTfpHHsFUjNMetOpX4	false	-	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99952	uniprotkb:O43586	intact:EBI-1384210|uniprotkb:Q53P42|intact:EBI-3959579|uniprotkb:B4E1E6|ensembl:ENSP00000175756	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	psi-mi:ptn18_human(display_long)|uniprotkb:Brain-derived phosphatase(gene name synonym)|uniprotkb:PTPN18(gene name)|psi-mi:PTPN18(display_short)|uniprotkb:BDP1(gene name synonym)	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dowbenko et al. (1998)	mint:MINT-8254333|doi:10.1074/jbc.273.2.989|pubmed:9422760	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8674056|mint:MINT-8254762	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055184.2|refseq:NP_001135842.1|ensembl:ENSG00000072135(gene)|ensembl:ENST00000175756(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:1901185"(negative regulation of ERBB signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:Q99952|rcsb pdb:2OC3|rcsb pdb:4GFU|rcsb pdb:4GFV|rcsb pdb:4NND|reactome:R-HSA-8863795|reactome:R-HSA-9008059|mint:MINT-8254765(identity)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|mint:MINT-8254764(identity)	-	-	-	comment:homomint|comment:mint|figure legend:F3; F5; F6|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/10/20	2014/10/16	rogid:xRrifp9kOwi0SLtlIFtSjiv4qN89606	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	intact-crc:76E340CF2CA35B5B|rigid:q6hX9PGwpjTfpHHsFUjNMetOpX4	false	mutation disrupting interaction:444-444(MINT-8255351)|mutation disrupting interaction:442-442(MINT-8255345)|mutation disrupting interaction:447-447(MINT-8255354)|mutation disrupting interaction:443-443(MINT-8255348)|mutation disrupting interaction:440-440(MINT-8255341)|mutation disrupting interaction:436-436(MINT-8255338)|mutation disrupting interaction:450-450(MINT-8255358)	mutation disrupting interaction:232-232(MINT-8254793)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99952	uniprotkb:O43586	intact:EBI-1384210|uniprotkb:Q53P42|intact:EBI-3959579|uniprotkb:B4E1E6|ensembl:ENSP00000175756	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	psi-mi:ptn18_human(display_long)|uniprotkb:Brain-derived phosphatase(gene name synonym)|uniprotkb:PTPN18(gene name)|psi-mi:PTPN18(display_short)|uniprotkb:BDP1(gene name synonym)	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dowbenko et al. (1998)	mint:MINT-8254333|doi:10.1074/jbc.273.2.989|pubmed:9422760	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8674107|mint:MINT-8254936	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055184.2|refseq:NP_001135842.1|ensembl:ENSG00000072135(gene)|ensembl:ENST00000175756(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:1901185"(negative regulation of ERBB signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:Q99952|rcsb pdb:2OC3|rcsb pdb:4GFU|rcsb pdb:4GFV|rcsb pdb:4NND|reactome:R-HSA-8863795|reactome:R-HSA-9008059|mint:MINT-8254938(identity)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|mint:MINT-8254939(identity)	-	comment:"Resulting Phenotypic qualities properties)[PATO]: PATO:0002221 (increased phosphorylation)"	-	figure legend:F4|comment:homomint|comment:mint|partial coverage:partial coverage	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2011/10/20	2014/10/16	rogid:xRrifp9kOwi0SLtlIFtSjiv4qN89606	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	intact-crc:E78124006C171351|rigid:q6hX9PGwpjTfpHHsFUjNMetOpX4	false	mutation increasing interaction:229-229(MINT-8255050)|mutation disrupting interaction:232-232(MINT-8255088)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43586	uniprotkb:Q99952	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-1384210|uniprotkb:Q53P42|intact:EBI-3959579|uniprotkb:B4E1E6|ensembl:ENSP00000175756	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:ptn18_human(display_long)|uniprotkb:Brain-derived phosphatase(gene name synonym)|uniprotkb:PTPN18(gene name)|psi-mi:PTPN18(display_short)|uniprotkb:BDP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dowbenko et al. (1998)	mint:MINT-8254333|doi:10.1074/jbc.273.2.989|pubmed:9422760	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8674125|mint:MINT-8255095	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|mint:MINT-8255102(identity)	refseq:NP_055184.2|refseq:NP_001135842.1|ensembl:ENSG00000072135(gene)|ensembl:ENST00000175756(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:1901185"(negative regulation of ERBB signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:Q99952|rcsb pdb:2OC3|rcsb pdb:4GFU|rcsb pdb:4GFV|rcsb pdb:4NND|reactome:R-HSA-8863795|reactome:R-HSA-9008059|mint:MINT-8255097(identity)	-	-	comment:"Resulting Phenotypic qualities properties)[PATO]: PATO:0002221 (increased phosphorylation)"	figure legend:F4|comment:homomint|comment:mint|partial coverage:partial coverage	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2011/10/20	2014/10/16	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:xRrifp9kOwi0SLtlIFtSjiv4qN89606	intact-crc:773DE96E0E5D05F1|rigid:q6hX9PGwpjTfpHHsFUjNMetOpX4	false	-	mutation disrupting interaction:232-232(MINT-8255098)|mutation increasing interaction:229-229(MINT-8255100)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)