#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P25801 uniprotkb:P23769 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 intact:EBI-2806671|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8|ensembl:ENSP00000345681|ensembl:ENSP00000417074 psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903267|imex:IM-16983-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|go:"GO:0001764"(neuron migration)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001709"(cell fate determination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0033993"(response to lipid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060872"(semicircular canal development)|go:"GO:0061042"(vascular wound healing)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097154"(GABAergic neuron differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000977"(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029522|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000179348(gene)|ensembl:ENST00000341105(transcript)|ensembl:ENST00000487848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development) - - - figure legend:fig 1C, 1E|inhibition:Peptide used to raise anti-GATA2 inhibited the interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/05/16 2014/10/16 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606 intact-crc:5879FD7FAE8BE159|rigid:296XoIY2mo5GQfFWOrECxUi0/CA false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P25801 uniprotkb:P17679 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 intact:EBI-3903251|uniprotkb:Q3UIH9|uniprotkb:Q7TMX8|ensembl:ENSMUSP00000033502 psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:gata1_mouse(display_long)|uniprotkb:Gata1(gene name)|psi-mi:Gata1(display_short)|uniprotkb:Gf-1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903690|imex:IM-16983-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD refseq:XP_011245750.1|refseq:NP_032115.1|dip:DIP-40883N|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P17679|rcsb pdb:1GNF|rcsb pdb:1Y0J|rcsb pdb:2L5E|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:3VD6|rcsb pdb:3VEK|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-983231|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|ensembl:ENSMUSG00000031162(gene)|ensembl:ENSMUST00000033502(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) - - - figure legend:fig 1C, 1E|inhibition:Peptide used to raise anti-RBTN2 antibodies inhibited interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/05/16 2014/10/16 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 rogid:zv2cIXaxDsuFj//cWvnvvL8jgiA10090 intact-crc:E8A185B9568F2F3B|rigid:ke0c8EowZIvHarTglcTxrbh9PTs false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P17679 uniprotkb:P25801 intact:EBI-3903251|uniprotkb:Q3UIH9|uniprotkb:Q7TMX8|ensembl:ENSMUSP00000033502 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 psi-mi:gata1_mouse(display_long)|uniprotkb:Gata1(gene name)|psi-mi:Gata1(display_short)|uniprotkb:Gf-1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3904247|imex:IM-16983-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245750.1|refseq:NP_032115.1|dip:DIP-40883N|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P17679|rcsb pdb:1GNF|rcsb pdb:1Y0J|rcsb pdb:2L5E|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:3VD6|rcsb pdb:3VEK|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-983231|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|ensembl:ENSMUSG00000031162(gene)|ensembl:ENSMUST00000033502(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD - - - figure legend:fig 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/05/16 2014/10/16 rogid:zv2cIXaxDsuFj//cWvnvvL8jgiA10090 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 intact-crc:DC3DD63625D34580|rigid:ke0c8EowZIvHarTglcTxrbh9PTs false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P25801 uniprotkb:P17679 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 intact:EBI-3903251|uniprotkb:Q3UIH9|uniprotkb:Q7TMX8|ensembl:ENSMUSP00000033502 psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:gata1_mouse(display_long)|uniprotkb:Gata1(gene name)|psi-mi:Gata1(display_short)|uniprotkb:Gf-1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903284|imex:IM-16983-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD refseq:XP_011245750.1|refseq:NP_032115.1|dip:DIP-40883N|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P17679|rcsb pdb:1GNF|rcsb pdb:1Y0J|rcsb pdb:2L5E|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:3VD6|rcsb pdb:3VEK|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-983231|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|ensembl:ENSMUSG00000031162(gene)|ensembl:ENSMUST00000033502(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) - - - figure legend:fig 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/05/16 2014/10/16 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 rogid:zv2cIXaxDsuFj//cWvnvvL8jgiA10090 intact-crc:B6FAD22047872D09|rigid:ke0c8EowZIvHarTglcTxrbh9PTs false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P25801 uniprotkb:P17542 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:"MI:0096"(pull down) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-3903737|imex:IM-16983-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) - - - figure legend:2A|caution:The coordinates of the bHLH region are not given n the paper so have been inferred from the UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/16 2014/10/16 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 intact-crc:C3F9969E9F7D23CA|rigid:ZFT0AbiVZA+woL3d3EBz/4CASzw false 35s radiolabel:?-? glutathione s tranferase tag:?-?|sufficient binding region:200..200-240..240(IPR001092) - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P25801 uniprotkb:P23769 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 intact:EBI-2806671|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8|ensembl:ENSP00000345681|ensembl:ENSP00000417074 psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short) psi-mi:"MI:0096"(pull down) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-3903730|imex:IM-16983-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|go:"GO:0001764"(neuron migration)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001709"(cell fate determination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0033993"(response to lipid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060872"(semicircular canal development)|go:"GO:0061042"(vascular wound healing)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097154"(GABAergic neuron differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000977"(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029522|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000179348(gene)|ensembl:ENST00000341105(transcript)|ensembl:ENST00000487848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development) - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/16 2014/10/16 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606 intact-crc:78B11C99F9BCA695|rigid:296XoIY2mo5GQfFWOrECxUi0/CA false 35s radiolabel:?-? maltose binding protein tag:?-?|sufficient binding region:230-480 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P15923 uniprotkb:P17542 intact:EBI-769630|uniprotkb:Q2TB40|uniprotkb:P15883|uniprotkb:Q14208|uniprotkb:Q14635|uniprotkb:Q14636|uniprotkb:Q9UPI9|uniprotkb:Q2TB39|intact:EBI-11119608|ensembl:ENSP00000262965 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 psi-mi:tfe2_human(display_long)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 1(gene name synonym)|uniprotkb:Transcription factor ITF-1(gene name synonym)|uniprotkb:Kappa-E2-binding factor(gene name synonym)|uniprotkb:TCF3(gene name)|psi-mi:TCF3(display_short)|uniprotkb:E2A(gene name synonym)|uniprotkb:ITF1(gene name synonym)|uniprotkb:BHLHB21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 21(gene name synonym) psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903760|imex:IM-16983-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129611.1|refseq:NP_003191.1|refseq:XP_016882669.1|refseq:XP_016882670.1|refseq:XP_016882671.1|dip:DIP-74N|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000071564(gene)|ensembl:ENST00000262965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2YPA|rcsb pdb:2YPB|rcsb pdb:3U5V|rcsb pdb:6MGN|reactome:R-HSA-525793|reactome:R-HSA-8939236|rcsb pdb:2MH0|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1HLH refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:EybpTkEZM4cIWyf25UVHfaOaP3Y9606 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 intact-crc:463CD630D10EBC6B|rigid:SN+35RpmpyWOvYOIDhBAYzNjwrI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25801 uniprotkb:P17542 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903764|imex:IM-16983-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 intact-crc:4108168777642959|rigid:ZFT0AbiVZA+woL3d3EBz/4CASzw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17679 uniprotkb:P25801 intact:EBI-3903251|uniprotkb:Q3UIH9|uniprotkb:Q7TMX8|ensembl:ENSMUSP00000033502 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 psi-mi:gata1_mouse(display_long)|uniprotkb:Gata1(gene name)|psi-mi:Gata1(display_short)|uniprotkb:Gf-1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903773|imex:IM-16983-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245750.1|refseq:NP_032115.1|dip:DIP-40883N|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P17679|rcsb pdb:1GNF|rcsb pdb:1Y0J|rcsb pdb:2L5E|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:3VD6|rcsb pdb:3VEK|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-983231|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|ensembl:ENSMUSG00000031162(gene)|ensembl:ENSMUST00000033502(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:zv2cIXaxDsuFj//cWvnvvL8jgiA10090 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 intact-crc:339E8461A6CA596E|rigid:ke0c8EowZIvHarTglcTxrbh9PTs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25801 uniprotkb:P17542 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903769|imex:IM-16983-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 intact-crc:3014195B36C4B7E8|rigid:ZFT0AbiVZA+woL3d3EBz/4CASzw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23769 uniprotkb:P25801 intact:EBI-2806671|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8|ensembl:ENSP00000345681|ensembl:ENSP00000417074 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short) psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903777|imex:IM-16983-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|go:"GO:0001764"(neuron migration)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001709"(cell fate determination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0033993"(response to lipid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060872"(semicircular canal development)|go:"GO:0061042"(vascular wound healing)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097154"(GABAergic neuron differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000977"(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029522|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000179348(gene)|ensembl:ENST00000341105(transcript)|ensembl:ENST00000487848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 intact-crc:F840111B5024232B|rigid:296XoIY2mo5GQfFWOrECxUi0/CA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17542 uniprotkb:P17679 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 intact:EBI-3903251|uniprotkb:Q3UIH9|uniprotkb:Q7TMX8|ensembl:ENSMUSP00000033502 psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:gata1_mouse(display_long)|uniprotkb:Gata1(gene name)|psi-mi:Gata1(display_short)|uniprotkb:Gf-1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903781|imex:IM-16983-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) refseq:XP_011245750.1|refseq:NP_032115.1|dip:DIP-40883N|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P17679|rcsb pdb:1GNF|rcsb pdb:1Y0J|rcsb pdb:2L5E|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:3VD6|rcsb pdb:3VEK|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-983231|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|ensembl:ENSMUSG00000031162(gene)|ensembl:ENSMUST00000033502(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 rogid:zv2cIXaxDsuFj//cWvnvvL8jgiA10090 intact-crc:4D45556D6D3E3C41|rigid:3OhDJYmG7lc7W4ZkBXPfcy6PRiY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17542 uniprotkb:P25801 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903781|imex:IM-16983-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 intact-crc:4D45556D6D3E3C41|rigid:3OhDJYmG7lc7W4ZkBXPfcy6PRiY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17542 uniprotkb:P25801 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903786|imex:IM-16983-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 intact-crc:08AD4C26587A5DED|rigid:RzzbvdZq4UGhuroERN6tboDvG4A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17542 uniprotkb:P23769 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 intact:EBI-2806671|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8|ensembl:ENSP00000345681|ensembl:ENSP00000417074 psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903786|imex:IM-16983-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|go:"GO:0001764"(neuron migration)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001709"(cell fate determination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0033993"(response to lipid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060872"(semicircular canal development)|go:"GO:0061042"(vascular wound healing)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097154"(GABAergic neuron differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000977"(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029522|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000179348(gene)|ensembl:ENST00000341105(transcript)|ensembl:ENST00000487848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development) - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606 intact-crc:08AD4C26587A5DED|rigid:RzzbvdZq4UGhuroERN6tboDvG4A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15923 uniprotkb:P17542 intact:EBI-769630|uniprotkb:Q2TB40|uniprotkb:P15883|uniprotkb:Q14208|uniprotkb:Q14635|uniprotkb:Q14636|uniprotkb:Q9UPI9|uniprotkb:Q2TB39|intact:EBI-11119608|ensembl:ENSP00000262965 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 psi-mi:tfe2_human(display_long)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 1(gene name synonym)|uniprotkb:Transcription factor ITF-1(gene name synonym)|uniprotkb:Kappa-E2-binding factor(gene name synonym)|uniprotkb:TCF3(gene name)|psi-mi:TCF3(display_short)|uniprotkb:E2A(gene name synonym)|uniprotkb:ITF1(gene name synonym)|uniprotkb:BHLHB21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 21(gene name synonym) psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903797|imex:IM-16983-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129611.1|refseq:NP_003191.1|refseq:XP_016882669.1|refseq:XP_016882670.1|refseq:XP_016882671.1|dip:DIP-74N|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000071564(gene)|ensembl:ENST00000262965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2YPA|rcsb pdb:2YPB|rcsb pdb:3U5V|rcsb pdb:6MGN|reactome:R-HSA-525793|reactome:R-HSA-8939236|rcsb pdb:2MH0|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1HLH refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:EybpTkEZM4cIWyf25UVHfaOaP3Y9606 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 intact-crc:990B51B1C3082B10|rigid:p5fNqev8JisS/kJ7UhBEjMR3h1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15923 uniprotkb:P25801 intact:EBI-769630|uniprotkb:Q2TB40|uniprotkb:P15883|uniprotkb:Q14208|uniprotkb:Q14635|uniprotkb:Q14636|uniprotkb:Q9UPI9|uniprotkb:Q2TB39|intact:EBI-11119608|ensembl:ENSP00000262965 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 psi-mi:tfe2_human(display_long)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 1(gene name synonym)|uniprotkb:Transcription factor ITF-1(gene name synonym)|uniprotkb:Kappa-E2-binding factor(gene name synonym)|uniprotkb:TCF3(gene name)|psi-mi:TCF3(display_short)|uniprotkb:E2A(gene name synonym)|uniprotkb:ITF1(gene name synonym)|uniprotkb:BHLHB21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 21(gene name synonym) psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903797|imex:IM-16983-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129611.1|refseq:NP_003191.1|refseq:XP_016882669.1|refseq:XP_016882670.1|refseq:XP_016882671.1|dip:DIP-74N|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000071564(gene)|ensembl:ENST00000262965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2YPA|rcsb pdb:2YPB|rcsb pdb:3U5V|rcsb pdb:6MGN|reactome:R-HSA-525793|reactome:R-HSA-8939236|rcsb pdb:2MH0|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1HLH refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:EybpTkEZM4cIWyf25UVHfaOaP3Y9606 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 intact-crc:990B51B1C3082B10|rigid:p5fNqev8JisS/kJ7UhBEjMR3h1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15923 uniprotkb:P23769 intact:EBI-769630|uniprotkb:Q2TB40|uniprotkb:P15883|uniprotkb:Q14208|uniprotkb:Q14635|uniprotkb:Q14636|uniprotkb:Q9UPI9|uniprotkb:Q2TB39|intact:EBI-11119608|ensembl:ENSP00000262965 intact:EBI-2806671|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8|ensembl:ENSP00000345681|ensembl:ENSP00000417074 psi-mi:tfe2_human(display_long)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 1(gene name synonym)|uniprotkb:Transcription factor ITF-1(gene name synonym)|uniprotkb:Kappa-E2-binding factor(gene name synonym)|uniprotkb:TCF3(gene name)|psi-mi:TCF3(display_short)|uniprotkb:E2A(gene name synonym)|uniprotkb:ITF1(gene name synonym)|uniprotkb:BHLHB21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 21(gene name synonym) psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903797|imex:IM-16983-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129611.1|refseq:NP_003191.1|refseq:XP_016882669.1|refseq:XP_016882670.1|refseq:XP_016882671.1|dip:DIP-74N|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000071564(gene)|ensembl:ENST00000262965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2YPA|rcsb pdb:2YPB|rcsb pdb:3U5V|rcsb pdb:6MGN|reactome:R-HSA-525793|reactome:R-HSA-8939236|rcsb pdb:2MH0|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1HLH refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|go:"GO:0001764"(neuron migration)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001709"(cell fate determination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0033993"(response to lipid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060872"(semicircular canal development)|go:"GO:0061042"(vascular wound healing)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097154"(GABAergic neuron differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000977"(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029522|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000179348(gene)|ensembl:ENST00000341105(transcript)|ensembl:ENST00000487848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development) - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:EybpTkEZM4cIWyf25UVHfaOaP3Y9606 rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606 intact-crc:990B51B1C3082B10|rigid:p5fNqev8JisS/kJ7UhBEjMR3h1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15923 uniprotkb:P25801 intact:EBI-769630|uniprotkb:Q2TB40|uniprotkb:P15883|uniprotkb:Q14208|uniprotkb:Q14635|uniprotkb:Q14636|uniprotkb:Q9UPI9|uniprotkb:Q2TB39|intact:EBI-11119608|ensembl:ENSP00000262965 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 psi-mi:tfe2_human(display_long)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 1(gene name synonym)|uniprotkb:Transcription factor ITF-1(gene name synonym)|uniprotkb:Kappa-E2-binding factor(gene name synonym)|uniprotkb:TCF3(gene name)|psi-mi:TCF3(display_short)|uniprotkb:E2A(gene name synonym)|uniprotkb:ITF1(gene name synonym)|uniprotkb:BHLHB21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 21(gene name synonym) psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903791|imex:IM-16983-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129611.1|refseq:NP_003191.1|refseq:XP_016882669.1|refseq:XP_016882670.1|refseq:XP_016882671.1|dip:DIP-74N|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000071564(gene)|ensembl:ENST00000262965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2YPA|rcsb pdb:2YPB|rcsb pdb:3U5V|rcsb pdb:6MGN|reactome:R-HSA-525793|reactome:R-HSA-8939236|rcsb pdb:2MH0|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1HLH refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:EybpTkEZM4cIWyf25UVHfaOaP3Y9606 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 intact-crc:BE0BCC27167ECF12|rigid:aC9DGUAIBShyfa0hu0p98RIJizk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15923 uniprotkb:P17542 intact:EBI-769630|uniprotkb:Q2TB40|uniprotkb:P15883|uniprotkb:Q14208|uniprotkb:Q14635|uniprotkb:Q14636|uniprotkb:Q9UPI9|uniprotkb:Q2TB39|intact:EBI-11119608|ensembl:ENSP00000262965 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 psi-mi:tfe2_human(display_long)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 1(gene name synonym)|uniprotkb:Transcription factor ITF-1(gene name synonym)|uniprotkb:Kappa-E2-binding factor(gene name synonym)|uniprotkb:TCF3(gene name)|psi-mi:TCF3(display_short)|uniprotkb:E2A(gene name synonym)|uniprotkb:ITF1(gene name synonym)|uniprotkb:BHLHB21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 21(gene name synonym) psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903791|imex:IM-16983-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129611.1|refseq:NP_003191.1|refseq:XP_016882669.1|refseq:XP_016882670.1|refseq:XP_016882671.1|dip:DIP-74N|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000071564(gene)|ensembl:ENST00000262965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2YPA|rcsb pdb:2YPB|rcsb pdb:3U5V|rcsb pdb:6MGN|reactome:R-HSA-525793|reactome:R-HSA-8939236|rcsb pdb:2MH0|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1HLH refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:EybpTkEZM4cIWyf25UVHfaOaP3Y9606 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 intact-crc:BE0BCC27167ECF12|rigid:aC9DGUAIBShyfa0hu0p98RIJizk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15923 uniprotkb:P17679 intact:EBI-769630|uniprotkb:Q2TB40|uniprotkb:P15883|uniprotkb:Q14208|uniprotkb:Q14635|uniprotkb:Q14636|uniprotkb:Q9UPI9|uniprotkb:Q2TB39|intact:EBI-11119608|ensembl:ENSP00000262965 intact:EBI-3903251|uniprotkb:Q3UIH9|uniprotkb:Q7TMX8|ensembl:ENSMUSP00000033502 psi-mi:tfe2_human(display_long)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 1(gene name synonym)|uniprotkb:Transcription factor ITF-1(gene name synonym)|uniprotkb:Kappa-E2-binding factor(gene name synonym)|uniprotkb:TCF3(gene name)|psi-mi:TCF3(display_short)|uniprotkb:E2A(gene name synonym)|uniprotkb:ITF1(gene name synonym)|uniprotkb:BHLHB21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 21(gene name synonym) psi-mi:gata1_mouse(display_long)|uniprotkb:Gata1(gene name)|psi-mi:Gata1(display_short)|uniprotkb:Gf-1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903791|imex:IM-16983-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129611.1|refseq:NP_003191.1|refseq:XP_016882669.1|refseq:XP_016882670.1|refseq:XP_016882671.1|dip:DIP-74N|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000071564(gene)|ensembl:ENST00000262965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2YPA|rcsb pdb:2YPB|rcsb pdb:3U5V|rcsb pdb:6MGN|reactome:R-HSA-525793|reactome:R-HSA-8939236|rcsb pdb:2MH0|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1HLH refseq:XP_011245750.1|refseq:NP_032115.1|dip:DIP-40883N|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P17679|rcsb pdb:1GNF|rcsb pdb:1Y0J|rcsb pdb:2L5E|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:3VD6|rcsb pdb:3VEK|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-983231|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|ensembl:ENSMUSG00000031162(gene)|ensembl:ENSMUST00000033502(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c3h10t1_2)|taxid:10090(Mouse embryonic fibroblast C3H10T1_2) - 2011/05/16 2014/10/16 rogid:EybpTkEZM4cIWyf25UVHfaOaP3Y9606 rogid:zv2cIXaxDsuFj//cWvnvvL8jgiA10090 intact-crc:BE0BCC27167ECF12|rigid:aC9DGUAIBShyfa0hu0p98RIJizk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17679 uniprotkb:P25801 intact:EBI-3903251|uniprotkb:Q3UIH9|uniprotkb:Q7TMX8|ensembl:ENSMUSP00000033502 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 psi-mi:gata1_mouse(display_long)|uniprotkb:Gata1(gene name)|psi-mi:Gata1(display_short)|uniprotkb:Gf-1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Osada et al. (1995) pubmed:7568177|imex:IM-16983 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3903254|imex:IM-16983-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245750.1|refseq:NP_032115.1|dip:DIP-40883N|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P17679|rcsb pdb:1GNF|rcsb pdb:1Y0J|rcsb pdb:2L5E|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:3VD6|rcsb pdb:3VEK|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-983231|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|ensembl:ENSMUSG00000031162(gene)|ensembl:ENSMUST00000033502(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD - - - figure legend:fig 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2011/05/16 2014/10/16 rogid:zv2cIXaxDsuFj//cWvnvvL8jgiA10090 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 intact-crc:4B675D70BC71811A|rigid:ke0c8EowZIvHarTglcTxrbh9PTs false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)