#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13326	uniprotkb:Q06124	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357316|imex:IM-16425-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2020/01/07	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	intact-crc:E163A96B252956CF|rigid:3qCpMfxyn9j3WQ4EOUB6DGRazCE	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O75923	uniprotkb:P54296	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357156|imex:IM-16425-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	intact-crc:5CA8A1CFD22AC3BC|rigid:rNwMCwZFK6f2uhTnqeKv/FIZCP8	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q03001	uniprotkb:Q96CV9	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357450|imex:IM-16425-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:BF5FD99774289C1C|rigid:CSQGqVx78mA9/BXHhqr6r8SWuvY	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O75190	uniprotkb:O75923	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357236|imex:IM-16425-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:D1A986BDD8189078|rigid:wyXI8I/tkVUcph9tT9O/+PP8YIs	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P35609	uniprotkb:Q9UKG1	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357660|imex:IM-16425-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:33139F57974B539B|rigid:A/vnC8xrA7X2lG3e4ePpF7bL+MY	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P20929	uniprotkb:O60662	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357588|imex:IM-16425-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	intact-crc:F2C91D4FCF0FE7D7|rigid:45Vw+WOmLKllAfBkvWncSjQzy2k	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q9BZ29	uniprotkb:P20929	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357609|imex:IM-16425-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:EAEB09194B2C8E71|rigid:oTvGvOw1arOgSezx2Onf+qU1Ovo	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q13326	uniprotkb:O75923	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357412|imex:IM-16425-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:BB0F74895CFD0264|rigid:5x0J6GQ8QRgGGVUDOclpkDRd0OQ	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P17661	uniprotkb:O75923	intact:EBI-1055572|uniprotkb:Q15787|uniprotkb:Q8IZR1|uniprotkb:Q8IZR6|uniprotkb:Q8NES2|uniprotkb:Q8NEU6|uniprotkb:Q8TAC4|uniprotkb:Q8TCX2|uniprotkb:Q8TD99|uniprotkb:Q9UHN5|uniprotkb:Q9UJ80|uniprotkb:Q549R7|uniprotkb:Q549R8|uniprotkb:Q549R9|ensembl:ENSP00000363071	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:desm_human(display_long)|uniprotkb:DES(gene name)|psi-mi:DES(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5356982|imex:IM-16425-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001918.3|ensembl:ENSG00000175084(gene)|ensembl:ENST00000373960(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005916"(fascia adherens)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|mint:P17661|reactome:R-HSA-390522	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:htjPzLKLLbRXxfKz9NUgMYMuIaY9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:64433E3B0143A777|rigid:prcvhcqwEoWP7C5Cduo2xD0lkms	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P21399	uniprotkb:P20929	intact:EBI-2847111|uniprotkb:Q5VZA7|uniprotkb:Q14652|uniprotkb:D3DRK7|ensembl:ENSP00000309477|ensembl:ENSP00000369255|ensembl:ENSP00000438733	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:acohc_human(display_long)|uniprotkb:ACO1(gene name)|psi-mi:ACO1(display_short)|uniprotkb:IREB1(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Ferritin repressor protein(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357676|imex:IM-16425-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516190.1|refseq:NP_001265281.1|refseq:NP_002188.1|refseq:XP_005251533.1|ensembl:ENSG00000122729(gene)|ensembl:ENST00000309951(transcript)|ensembl:ENST00000379923(transcript)|ensembl:ENST00000541043(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR029784|interpro:IPR036008|interpro:IPR044137|mint:P21399|rcsb pdb:2B3X|rcsb pdb:2B3Y|reactome:R-HSA-917937|go:"GO:0009791"(post-embryonic development)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:hcZPPf3fTfqol8El1L5kwVEljyY9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:BE3A7503CB2F9CB1|rigid:bjWmwgoUxVJrLdC0mB2/JlHFsws	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P52179	uniprotkb:O75923	intact:EBI-5353249|uniprotkb:Q14BD6|uniprotkb:Q6H969|uniprotkb:Q6ZUU0|ensembl:ENSP00000348821	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:myom1_human(display_long)|uniprotkb:MYOM1(gene name)|psi-mi:MYOM1(display_short)|uniprotkb:190 kDa connectin-associated protein(gene name synonym)|uniprotkb:190 kDa titin-associated protein(gene name synonym)|uniprotkb:Myomesin family member 1(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5356842|imex:IM-16425-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59649N|refseq:NP_003794.3|refseq:NP_062830.1|ensembl:ENSG00000101605(gene)|ensembl:ENST00000356443(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P52179|rcsb pdb:2R15|rcsb pdb:2Y23|rcsb pdb:2Y25|rcsb pdb:3RBS|rcsb pdb:5FM4|rcsb pdb:5FM5|rcsb pdb:5FM8|rcsb pdb:6T3O	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:5lfd5o+54eyer647zxvU0LX1wpM9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:769C6F5B1FCB08E8|rigid:AuWRSlO2T5qr0xzVxQQGvSSxSZc	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P35609	uniprotkb:O75923	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357042|imex:IM-16425-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:7D50261BCAC3C4FB|rigid:TZPLcsNwCB5w09wTinI05b0VzAA	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q8TCU4	uniprotkb:O75923	intact:EBI-308651|uniprotkb:Q53S05|uniprotkb:Q580Q8|uniprotkb:Q86VP9|uniprotkb:Q9Y4G4|ensembl:ENSP00000482968|uniprotkb:A0A087WZY3	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:alms1_human(display_long)|uniprotkb:ALMS1(gene name)|psi-mi:ALMS1(display_short)|uniprotkb:KIAA0328(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357184|imex:IM-16425-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000116127(gene)|ensembl:ENST00000613296(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0008017"(microtubule binding)|go:"GO:0016197"(endosomal transport)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR028781|interpro:IPR029299|interpro:IPR040972|mint:Q8TCU4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055935.4	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:e91Hcs947kpQHPVhWAJRtYegdPg9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:091E9DFD7B75E297|rigid:oxv5dWTF3geQeVZtqpBK2TIvTt8	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O95295	uniprotkb:O75923	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357023|imex:IM-16425-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:26364761FB394207|rigid:CPZSgBkwSF644j933DxTx0N69l8	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q9UKG1	uniprotkb:O75923	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357057|imex:IM-16425-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:8C84BFA7B73AB93C|rigid:gf7I8HDoWGpDVVnH3OUaPLKc/9c	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P20929	uniprotkb:Q96CV9	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357463|imex:IM-16425-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:470AC68FECFCD575|rigid:i9WTrl4czIp6sKLsWpQsAlzkQuc	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q96CV9	uniprotkb:Q14BN4	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357483|imex:IM-16425-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606	intact-crc:F4BC152EAA17378F|rigid:5aSoOuW3zxbcsTNvce56FlFRCfQ	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q9Y3Z3	uniprotkb:O75923	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357222|imex:IM-16425-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:9539E3A563EEA9D2|rigid:c7ntomhMDZXrC9dKxMyBXRV6JeQ	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O75923	uniprotkb:Q8WZ42	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357260|imex:IM-16425-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:C2665F6CFF9D2BEA|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P04275	uniprotkb:Q96CV9	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357436|imex:IM-16425-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:5039DA6606AE6BDD|rigid:nQFg8NSl3CKXDWZft0+Q4pHJKHw	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O75923	uniprotkb:Q16760	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-719333|uniprotkb:Q14158|uniprotkb:Q6PK55|uniprotkb:Q8NG53|ensembl:ENSP00000264057|ensembl:ENSP00000487220	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:dgkd_human(display_long)|uniprotkb:Diglyceride kinase delta(gene name synonym)|uniprotkb:130 kDa diacylglycerol kinase(gene name synonym)|uniprotkb:DGKD(gene name)|psi-mi:DGKD(display_short)|uniprotkb:KIAA0145(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357170|imex:IM-16425-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	refseq:NP_003639.2|refseq:NP_690618.2|ensembl:ENSG00000077044(gene)|ensembl:ENSG00000280873(gene)|ensembl:ENST00000264057(transcript)|ensembl:ENST00000628356(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010033"(response to organic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090038"(negative regulation of protein kinase C signaling)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037606|interpro:IPR037607|mint:Q16760|rcsb pdb:1R79|rcsb pdb:3BQ7|reactome:R-HSA-114508|dip:DIP-29646N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:rMLPKsHWpeF6qbY0eBQcCeFyMo09606	intact-crc:F9D87B12365E4683|rigid:OItHv/iYKK97rX3weppyPJBMmx0	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P54296	uniprotkb:P21817	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-1221290|uniprotkb:Q16314|uniprotkb:Q16368|uniprotkb:Q9NPK1|uniprotkb:Q9P1U4|ensembl:ENSP00000352608	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:ryr1_human(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:RYDR(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357555|imex:IM-16425-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296	refseq:NP_000531.2|refseq:NP_001036188.1|dip:DIP-29708N|ensembl:ENSG00000196218(gene)|ensembl:ENST00000359596(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031674"(I band)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:6UHI|rcsb pdb:6UHS|reactome:R-HSA-2672351|reactome:R-HSA-5578775	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:WHlPtd5++5f+9GX0IGshsqJCOTg9606	intact-crc:A9B074E7067D13B6|rigid:F/BZnuGxcVQrM0kHfICU26VwylA	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O75923	uniprotkb:Q14315	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357088|imex:IM-16425-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606	intact-crc:1AE7CF85130F72D8|rigid:AXAxTcZlU7nSpNikcl4AFyrqxao	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q13326	uniprotkb:O75190	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357396|imex:IM-16425-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:679EB2ED59B69B31|rigid:NKAqXZfmYgfpJEF6LIV3aRchIdU	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q9UNH7	uniprotkb:Q96CV9	intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357503|imex:IM-16425-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:754134892A015B16|rigid:zjXWH/zYtC70GAiqaTnw4icK5HA	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q9UKG1	uniprotkb:Q03001	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357625|imex:IM-16425-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	intact-crc:6C8383C7FFE4D929|rigid:YSAscY+3OZ3GAYU/rvYhQm2QGSU	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P54296	uniprotkb:P35609	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357569|imex:IM-16425-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	intact-crc:E33F813FF25B291B|rigid:Od9gbwfo4GQrJsc8X0shHm1G/So	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O75923	uniprotkb:Q96CV9	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357074|imex:IM-16425-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:5F58E5F73CF6FC09|rigid:/aYgkAFuAPKe9oj3BsUCkZ4YX4I	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P21399	uniprotkb:Q13326	intact:EBI-2847111|uniprotkb:Q5VZA7|uniprotkb:Q14652|uniprotkb:D3DRK7|ensembl:ENSP00000309477|ensembl:ENSP00000369255|ensembl:ENSP00000438733	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	psi-mi:acohc_human(display_long)|uniprotkb:ACO1(gene name)|psi-mi:ACO1(display_short)|uniprotkb:IREB1(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Ferritin repressor protein(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym)	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357341|imex:IM-16425-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516190.1|refseq:NP_001265281.1|refseq:NP_002188.1|refseq:XP_005251533.1|ensembl:ENSG00000122729(gene)|ensembl:ENST00000309951(transcript)|ensembl:ENST00000379923(transcript)|ensembl:ENST00000541043(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR029784|interpro:IPR036008|interpro:IPR044137|mint:P21399|rcsb pdb:2B3X|rcsb pdb:2B3Y|reactome:R-HSA-917937|go:"GO:0009791"(post-embryonic development)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:hcZPPf3fTfqol8El1L5kwVEljyY9606	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	intact-crc:9D3CDC623E44DD6F|rigid:LVF/mRXprKOabQWnqHbTYIchFaE	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q96CV9	uniprotkb:Q8WZ42	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357536|imex:IM-16425-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:A19F0B9E91F7C3F0|rigid:xZV8c1ZmMjdKg078F3XAjOlEwEA	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q13023	uniprotkb:Q96CV9	intact:EBI-1056102|uniprotkb:O15028|uniprotkb:A7E2D4|uniprotkb:A7E242|ensembl:ENSP00000280979	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:akap6_human(display_long)|uniprotkb:KIAA0311(gene name synonym)|uniprotkb:AKAP6(gene name)|psi-mi:AKAP6(display_short)|uniprotkb:AKAP100(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 6(gene name synonym)|uniprotkb:A-kinase anchor protein 100 kDa(gene name synonym)|uniprotkb:mAKAP(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357521|imex:IM-16425-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004265.3|ensembl:ENSG00000151320(gene)|ensembl:ENST00000280979(transcript)|go:"GO:0001508"(action potential)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005901"(caveola)|go:"GO:0006605"(protein targeting)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030315"(T-tubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902261"(positive regulation of delayed rectifier potassium channel activity)|interpro:IPR018159|mint:Q13023	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:N0OdGKZGo4mR8XfkEGELhmoAGlA9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:802E978CD1257252|rigid:mcMkLncFvAsmvzdop0v26+5gBE8	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O75923	uniprotkb:P20929	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357104|imex:IM-16425-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:CB4B82BE9796E9E8|rigid:waTxFmvNU6HpJFKRRLzHtd9Oo3A	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q9UKG1	uniprotkb:Q8WXH0	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-2372294|uniprotkb:Q540G1|uniprotkb:Q8N1S3|uniprotkb:Q8NF49|uniprotkb:Q8TER7|uniprotkb:Q8WWW3|uniprotkb:Q8WWW4|uniprotkb:Q8WWW5|uniprotkb:Q8WXH1|uniprotkb:Q9NU50|uniprotkb:Q9UFQ4|uniprotkb:Q9Y2L4|uniprotkb:Q9Y4R1|uniprotkb:Q86YP9|uniprotkb:B4DND7|uniprotkb:B4DPR6|uniprotkb:I6XXQ5|ensembl:ENSP00000341781	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:syne2_human(display_long)|uniprotkb:SYNE2(gene name)|psi-mi:SYNE2(display_short)|uniprotkb:KIAA1011(gene name synonym)|uniprotkb:NUA(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 2(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 2(gene name synonym)|uniprotkb:Nucleus and actin connecting element protein(gene name synonym)|uniprotkb:KASH domain-containing protein 2(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357640|imex:IM-16425-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N	ensembl:ENSP00000344528|ensembl:ENSP00000341781|ensembl:ENST00000358025|ensembl:ENSP00000350719|ensembl:ENST00000458046|ensembl:ENSP00000391937|ensembl:ENST00000555002|ensembl:ENSP00000450831|ensembl:ENST00000341472|refseq:NP_055995.4|refseq:NP_878914.1|refseq:NP_878917.1|refseq:NP_878918.2|dip:DIP-53409N|ensembl:ENSG00000054654(gene)|ensembl:ENST00000344113(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005925"(focal adhesion)|go:"GO:0007097"(nuclear migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR030266|interpro:IPR036872|rcsb pdb:4DXS|rcsb pdb:4FI9|rcsb pdb:6XF1|reactome:R-HSA-1221632	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:wLHWOXR+dUHkcs93g+F2av/9wm49606	intact-crc:E92124C79D4C7E24|rigid:nIOzHWyhiY4677OqvnGDJjIl/Xo	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q8N3K9	uniprotkb:O75923	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5357119|imex:IM-16425-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	figure legend:4 and table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:6F83F811825B40F0|rigid:zcJ6wZwV5qZBS/Lil/11w0eDZ8Y	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O75386	uniprotkb:P20929	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6258733|imex:IM-16425-882	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028	-	-	-	figure legend:table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:BC428CF04962BA60|rigid:Xd/F4FQ7XSSuNoPn3FGytwtgdC0	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q8WZ42	uniprotkb:P54296	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6258754|imex:IM-16425-884	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296	-	-	-	figure legend:Figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	intact-crc:1584AF1B213640C7|rigid:imvOt5UAnUDJq5ZAscY+KiKLhEQ	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O60662	uniprotkb:P20929	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6258750|imex:IM-16425-883	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028	-	-	-	figure legend:table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:30C21DEA85F54593|rigid:45Vw+WOmLKllAfBkvWncSjQzy2k	false	-	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P48675	uniprotkb:P04764	intact:EBI-917611	intact:EBI-915852|uniprotkb:Q66HI3|uniprotkb:Q6AYV3|uniprotkb:Q6P504|ensembl:ENSRNOP00000024106|ensembl:ENSRNOP00000073191	psi-mi:desm_rat(display_long)|uniprotkb:Des(gene name)|psi-mi:Des(display_short)	psi-mi:enoa_rat(display_long)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5350884|imex:IM-16425-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR039008|rgd:620686|refseq:NP_071976.1|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|reactome:R-RNO-390522|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005921"(gap junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043292"(contractile fiber)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0097512"(cardiac myofibril)	rgd:2553|refseq:NP_001103378.1|refseq:NP_036686.2|ensembl:ENSRNOG00000017895(gene)|ensembl:ENSRNOT00000024106(transcript)|ensembl:ENSRNOT00000081579(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P04764|reactome:R-RNO-70171|reactome:R-RNO-70263	-	-	-	figure legend:Figure 2 Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2014/10/16	rogid:28nwNWVR78n52KyhEAEHZ8W0E2U10116	rogid:JPjYBxy1gOmhfZso6+adhg5N8UM10116	intact-crc:4F4B18C6E27BA105|rigid:0hrOpQxGgizSrgdb+NmaSxemTIM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-6257388	intact:EBI-6258428	-	-	psi-mi:d3zl02_rat(display_short)|psi-mi:EBI-6257388(display_long)|uniprotkb:Dysf(gene name)|psi-mi:Dysf(display_short)	psi-mi:f1m7t8_rat(display_short)|psi-mi:EBI-6258428(display_long)|uniprotkb:Myom1(gene name)|psi-mi:Myom1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5353274|imex:IM-16425-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:D3ZL02(uniprot-removed-ac)	uniprotkb:F1M7T8(uniprot-removed-ac)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Figure 2 Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2014/10/16	rogid:450CMgf9EsK4yvOI+A/iqiaFQw810116	rogid:WXWZKp1IzDn3HuvdpRXOEhDj1Wo10116	intact-crc:DDD93CB63BA67F17|rigid:P3BgpPZSzgjPY64ObpY7G6jp4M4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P60192	uniprotkb:D3ZCV0	intact:EBI-917825|ensembl:ENSRNOP00000018830	intact:EBI-6257410|ensembl:ENSRNOP00000024098	psi-mi:snapn_rat(display_long)|uniprotkb:Snapap(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:Snapin(gene name)|psi-mi:Snapin(display_short)|uniprotkb:Snap25bp(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)|uniprotkb:Bloc1s7(gene name synonym)	psi-mi:d3zcv0_rat(display_long)|uniprotkb:Actn2(gene name)|psi-mi:Actn2(display_short)|uniprotkb:rCG_30552(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5351457|imex:IM-16425-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1560377|refseq:NP_001164047.1|ensembl:ENSRNOG00000013356(gene)|ensembl:ENSRNOT00000018830(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|mint:P60192|reactome:R-RNO-432722	ensembl:ENSRNOG00000017833(gene)|ensembl:ENSRNOT00000024098(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:D3ZCV0|reactome:R-RNO-114608|reactome:R-RNO-390522|reactome:R-RNO-438066|reactome:R-RNO-5673001|rgd:1308097|refseq:NP_001163796.1	-	-	-	figure legend:Figure 2 Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2014/10/16	rogid:L66mKyBsv3V0+K6AhcHvc540uX810116	rogid:r5g0YjP9pqmJjxEfxmBL7xMzjBI10116	intact-crc:52E2B04B34BF6D78|rigid:OkSUfOeyzMYxoVXAXvN1cFFw+CA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:D3ZWA8	intact:EBI-6257388	intact:EBI-6258454|ensembl:ENSRNOP00000018413	-	psi-mi:d3zwa8_rat(display_long)|uniprotkb:Appl1(gene name)|psi-mi:Appl1(display_short)	psi-mi:d3zl02_rat(display_short)|psi-mi:EBI-6257388(display_long)|uniprotkb:Dysf(gene name)|psi-mi:Dysf(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5353191|imex:IM-16425-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000013574(gene)|ensembl:ENSRNOT00000018413(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|reactome:R-RNO-418889|rgd:1309388	uniprotkb:D3ZL02(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Figure 2 Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2015/07/27	rogid:+923bDWNIVwoey7MnTNkOSo81Vs10116	rogid:450CMgf9EsK4yvOI+A/iqiaFQw810116	intact-crc:6FB4796BA0BEC506|rigid:qD3CYhn/iCo6X/4aAJlVdK4FzPo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48675	intact:EBI-6257388	intact:EBI-917611	-	psi-mi:desm_rat(display_long)|uniprotkb:Des(gene name)|psi-mi:Des(display_short)	psi-mi:d3zl02_rat(display_short)|psi-mi:EBI-6257388(display_long)|uniprotkb:Dysf(gene name)|psi-mi:Dysf(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5353236|imex:IM-16425-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR039008|rgd:620686|refseq:NP_071976.1|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|reactome:R-RNO-390522|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005921"(gap junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043292"(contractile fiber)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0097512"(cardiac myofibril)	uniprotkb:D3ZL02(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Figure 2 Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2014/10/16	rogid:28nwNWVR78n52KyhEAEHZ8W0E2U10116	rogid:450CMgf9EsK4yvOI+A/iqiaFQw810116	intact-crc:AFD2E4B95BBBED27|rigid:ZquxysuHLJWEcJ68gR0oTwLgxYI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-6257388	uniprotkb:D3ZCV0	-	intact:EBI-6257410|ensembl:ENSRNOP00000024098	psi-mi:d3zl02_rat(display_short)|psi-mi:EBI-6257388(display_long)|uniprotkb:Dysf(gene name)|psi-mi:Dysf(display_short)	psi-mi:d3zcv0_rat(display_long)|uniprotkb:Actn2(gene name)|psi-mi:Actn2(display_short)|uniprotkb:rCG_30552(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5353206|imex:IM-16425-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:D3ZL02(uniprot-removed-ac)	ensembl:ENSRNOG00000017833(gene)|ensembl:ENSRNOT00000024098(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:D3ZCV0|reactome:R-RNO-114608|reactome:R-RNO-390522|reactome:R-RNO-438066|reactome:R-RNO-5673001|rgd:1308097|refseq:NP_001163796.1	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Figure 2 Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2014/10/16	rogid:450CMgf9EsK4yvOI+A/iqiaFQw810116	rogid:r5g0YjP9pqmJjxEfxmBL7xMzjBI10116	intact-crc:0C8B5E308270D33B|rigid:8yvDAMdN3DizL67R3zgiwqDSOXc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O88658	intact:EBI-6257388	intact:EBI-924646|uniprotkb:Q65Z71|uniprotkb:Q8R524|ensembl:ENSRNOP00000074322|ensembl:ENSRNOP00000075522	-	psi-mi:kif1b_rat(display_long)|uniprotkb:Kif1b(gene name)|psi-mi:Kif1b(display_short)	psi-mi:d3zl02_rat(display_short)|psi-mi:EBI-6257388(display_long)|uniprotkb:Dysf(gene name)|psi-mi:Dysf(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5353168|imex:IM-16425-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621520|refseq:NP_476548.1|ensembl:ENSRNOG00000057626(gene)|ensembl:ENSRNOT00000087739(transcript)|ensembl:ENSRNOT00000089099(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010970"(transport along microtubule)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904647"(response to rotenone)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990778"(protein localization to cell periphery)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|reactome:R-RNO-2132295|reactome:R-RNO-6811434|reactome:R-RNO-983189	uniprotkb:D3ZL02(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Figure 2 Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2014/10/16	rogid:pOpPlcTNXi27NgtBAcTpwmRV7EE10116	rogid:450CMgf9EsK4yvOI+A/iqiaFQw810116	intact-crc:EBB2107189F71034|rigid:vxo+RmdJZCxZ9oxlamsM2le+h6M	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-6257609	uniprotkb:Q5D001	-	intact:EBI-6257702	psi-mi:telt_rat_protein(display_short)|psi-mi:EBI-6257609(display_long)	psi-mi:q5d001_rat(display_long)|uniprotkb:Adpgk(gene name)|psi-mi:Adpgk(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5351637|imex:IM-16425-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O15273(see-also)	go:"GO:0006096"(glycolytic process)|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|interpro:IPR007666(ADP-specific phosphofructokinase/glucokinase)|interpro:IPR029056	-	-	-	figure legend:Figure 2 Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2014/10/16	-	rogid:zUSi86Q5wxBzuOlRh7qrgTnF+/k10116	intact-crc:D72D2AB9FFBD82F6	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-6257388	uniprotkb:P60192	-	intact:EBI-917825|ensembl:ENSRNOP00000018830	psi-mi:d3zl02_rat(display_short)|psi-mi:EBI-6257388(display_long)|uniprotkb:Dysf(gene name)|psi-mi:Dysf(display_short)	psi-mi:snapn_rat(display_long)|uniprotkb:Snapap(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:Snapin(gene name)|psi-mi:Snapin(display_short)|uniprotkb:Snap25bp(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)|uniprotkb:Bloc1s7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5353223|imex:IM-16425-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:D3ZL02(uniprot-removed-ac)	rgd:1560377|refseq:NP_001164047.1|ensembl:ENSRNOG00000013356(gene)|ensembl:ENSRNOT00000018830(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|mint:P60192|reactome:R-RNO-432722	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Figure 2 Table S2|comment:Both the proteins involved in interaction are part of the Bait list, hence, bait could not be attributed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2014/10/16	rogid:450CMgf9EsK4yvOI+A/iqiaFQw810116	rogid:L66mKyBsv3V0+K6AhcHvc540uX810116	intact-crc:D784ABB77434431F|rigid:hi1mi7a1UNxrOjfF67ETO6/0Jqg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-6257609	uniprotkb:Q9ER30	-	intact:EBI-919869|ensembl:ENSRNOP00000009969	psi-mi:telt_rat_protein(display_short)|psi-mi:EBI-6257609(display_long)	psi-mi:klh41_rat(display_long)|uniprotkb:Klhl41(gene name)|psi-mi:Klhl41(display_short)|uniprotkb:Kbtbd10(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Krp1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5353110|imex:IM-16425-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O15273(see-also)	rgd:620852|refseq:NP_476539.1|ensembl:ENSRNOG00000007461(gene)|ensembl:ENSRNOT00000009969(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|rcsb pdb:2WOZ|reactome:R-RNO-8951664|reactome:R-RNO-983168	-	-	-	figure legend:Figure 2 Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2014/10/16	-	rogid:hmWCdhdr4LTDXNsF92pxEFe58e410116	intact-crc:CC132679FED78ED7	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZM5	intact:EBI-6258444	intact:EBI-920097|ensembl:ENSRNOP00000071079	-	psi-mi:abi1_rat(display_long)|uniprotkb:Abi1(gene name)|psi-mi:Abi1(display_short)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)	psi-mi:d4adw6_rat(display_short)|psi-mi:EBI-6258444(display_long)|uniprotkb:Ktn1(gene name)|psi-mi:Ktn1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5333868|imex:IM-16425-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621008|refseq:XP_006254416.1|dip:DIP-36968N|ensembl:ENSRNOG00000031325(gene)|ensembl:ENSRNOT00000091023(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0031252"(cell leading edge)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043005"(neuron projection)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q9QZM5|reactome:R-RNO-2029482|reactome:R-RNO-4420097|reactome:R-RNO-5663213|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013423	uniprotkb:D4ADW6(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Figure 2 Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10114(rat-r9)|taxid:10114(Rat R9 embryonic fibroblast)	-	2011/12/16	2014/10/16	rogid:CjsnJsS1Qxx1udsrO+knqWLXKkc10116	rogid:RaM+S7LU0SzG9hOgjOF87nbUO2Q10116	intact-crc:DD42CCB476D5E4D8|rigid:0EWpBCM/9CyyAM+Xq4EtTL6MhsM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17661	uniprotkb:O75923	intact:EBI-1055572|uniprotkb:Q15787|uniprotkb:Q8IZR1|uniprotkb:Q8IZR6|uniprotkb:Q8NES2|uniprotkb:Q8NEU6|uniprotkb:Q8TAC4|uniprotkb:Q8TCX2|uniprotkb:Q8TD99|uniprotkb:Q9UHN5|uniprotkb:Q9UJ80|uniprotkb:Q549R7|uniprotkb:Q549R8|uniprotkb:Q549R9|ensembl:ENSP00000363071	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:desm_human(display_long)|uniprotkb:DES(gene name)|psi-mi:DES(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5356186|imex:IM-16425-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001918.3|ensembl:ENSG00000175084(gene)|ensembl:ENST00000373960(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005916"(fascia adherens)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|mint:P17661|reactome:R-HSA-390522	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	comment:Coloc_Strong|figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:htjPzLKLLbRXxfKz9NUgMYMuIaY9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:A43B71BDA612CFEE|rigid:prcvhcqwEoWP7C5Cduo2xD0lkms	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O75923	uniprotkb:O95295	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5356158|imex:IM-16425-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1	-	-	-	comment:Coloc_Small|figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:CA6C15654F5412EC|rigid:CPZSgBkwSF644j933DxTx0N69l8	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O60333	uniprotkb:O75923	intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|ensembl:ENSP00000366290|ensembl:ENSP00000502065|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5354411|imex:IM-16425-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000054523(gene)|ensembl:ENST00000377086(transcript)|ensembl:ENST00000676179(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	comment:Coloc_Strong|figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:0961679077252F96|rigid:95gwAP0Zqhkw/zXZ7jW6nY3hW0I	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O75923	uniprotkb:Q96CV9	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5354392|imex:IM-16425-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	-	-	-	comment:Coloc_Strong|figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:54EED73CFDFAA576|rigid:/aYgkAFuAPKe9oj3BsUCkZ4YX4I	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O75923	uniprotkb:Q8N3K9	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5354318|imex:IM-16425-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9	-	-	-	comment:Coloc_Strong|figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	intact-crc:EAD5EAE79395DD0F|rigid:zcJ6wZwV5qZBS/Lil/11w0eDZ8Y	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O75923	uniprotkb:Q16760	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-719333|uniprotkb:Q14158|uniprotkb:Q6PK55|uniprotkb:Q8NG53|ensembl:ENSP00000264057|ensembl:ENSP00000487220	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:dgkd_human(display_long)|uniprotkb:Diglyceride kinase delta(gene name synonym)|uniprotkb:130 kDa diacylglycerol kinase(gene name synonym)|uniprotkb:DGKD(gene name)|psi-mi:DGKD(display_short)|uniprotkb:KIAA0145(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5354291|imex:IM-16425-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	refseq:NP_003639.2|refseq:NP_690618.2|ensembl:ENSG00000077044(gene)|ensembl:ENSG00000280873(gene)|ensembl:ENST00000264057(transcript)|ensembl:ENST00000628356(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010033"(response to organic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090038"(negative regulation of protein kinase C signaling)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037606|interpro:IPR037607|mint:Q16760|rcsb pdb:1R79|rcsb pdb:3BQ7|reactome:R-HSA-114508|dip:DIP-29646N	-	-	-	comment:Coloc_Medium|figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:rMLPKsHWpeF6qbY0eBQcCeFyMo09606	intact-crc:631E3D5FAE60CCC1|rigid:OItHv/iYKK97rX3weppyPJBMmx0	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q14315	uniprotkb:O75923	intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5354360|imex:IM-16425-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	comment:Coloc_Strong|figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:ADFC4745EC3389CE|rigid:AXAxTcZlU7nSpNikcl4AFyrqxao	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q8TCU4	uniprotkb:O75923	intact:EBI-308651|uniprotkb:Q53S05|uniprotkb:Q580Q8|uniprotkb:Q86VP9|uniprotkb:Q9Y4G4|ensembl:ENSP00000482968|uniprotkb:A0A087WZY3	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:alms1_human(display_long)|uniprotkb:ALMS1(gene name)|psi-mi:ALMS1(display_short)|uniprotkb:KIAA0328(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5354239|imex:IM-16425-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000116127(gene)|ensembl:ENST00000613296(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0008017"(microtubule binding)|go:"GO:0016197"(endosomal transport)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR028781|interpro:IPR029299|interpro:IPR040972|mint:Q8TCU4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055935.4	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	-	-	-	comment:Coloc_Medium|figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2018/04/06	rogid:e91Hcs947kpQHPVhWAJRtYegdPg9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:3451F10F97F1A9B4|rigid:oxv5dWTF3geQeVZtqpBK2TIvTt8	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O75923	uniprotkb:P20929	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5354342|imex:IM-16425-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028	-	-	-	comment:Coloc_Medium|figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:2C63E1A80C5CB625|rigid:waTxFmvNU6HpJFKRRLzHtd9Oo3A	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q8IZP0	uniprotkb:Q03001	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652673|imex:IM-16425-55	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	intact-crc:90DBBC2925CDEEFB|rigid:AD8fpSZHa68JjNpcmVHOGFQ7P2Q	false	sufficient binding region:1-476	sufficient binding region:2831-7570	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UP2	uniprotkb:Q8IZP0	intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym)	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652741|imex:IM-16425-59	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N|genbank_protein_gi:33620774(identity)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	intact-crc:1E473DC244C3FFD6|rigid:XeV3fuKM7IqgsgNm27RzNJmv8d8	false	sufficient binding region:615-1357	sufficient binding region:1-476	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZU52	uniprotkb:Q8IZP0	intact:EBI-739493|uniprotkb:O43158|uniprotkb:Q5TF20|uniprotkb:Q7L2M2|ensembl:ENSP00000435150|uniprotkb:B3KRE5|uniprotkb:E1P573	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	psi-mi:k0408_human(display_long)|uniprotkb:KIAA0408(gene name)|psi-mi:KIAA0408(display_short)	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652724|imex:IM-16425-58	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055517.3|ensembl:ENSG00000189367(gene)|ensembl:ENST00000483725(transcript)|interpro:IPR027882|mint:Q6ZU52|ensembl:ENSP00000435150|genbank_protein_gi:59806362(identity)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Ys9F4yIzuccTYU42mOIlc/I4yYo9606	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	intact-crc:C82897FC9291182F|rigid:PeEY454dKlESWG6QgwrLrM3RVBo	false	sufficient binding region:139-694	sufficient binding region:1-476	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IZP0	uniprotkb:P61978	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652707|imex:IM-16425-57	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N|genbank_protein_gi:14165436(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	intact-crc:E1297E7809934A5A|rigid:aRY8Gs0P2TgbGKzQGQC2ArLeC4Q	false	sufficient binding region:1-476	sufficient binding region:261-463	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03001	uniprotkb:Q8IZP0	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652690|imex:IM-16425-56	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	intact-crc:F9A4339A481A0EC4|rigid:AD8fpSZHa68JjNpcmVHOGFQ7P2Q	false	sufficient binding region:3809-7570	sufficient binding region:1-476	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IZP0	uniprotkb:Q8WXH0	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	intact:EBI-2372294|uniprotkb:Q540G1|uniprotkb:Q8N1S3|uniprotkb:Q8NF49|uniprotkb:Q8TER7|uniprotkb:Q8WWW3|uniprotkb:Q8WWW4|uniprotkb:Q8WWW5|uniprotkb:Q8WXH1|uniprotkb:Q9NU50|uniprotkb:Q9UFQ4|uniprotkb:Q9Y2L4|uniprotkb:Q9Y4R1|uniprotkb:Q86YP9|uniprotkb:B4DND7|uniprotkb:B4DPR6|uniprotkb:I6XXQ5|ensembl:ENSP00000341781	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:syne2_human(display_long)|uniprotkb:SYNE2(gene name)|psi-mi:SYNE2(display_short)|uniprotkb:KIAA1011(gene name synonym)|uniprotkb:NUA(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 2(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 2(gene name synonym)|uniprotkb:Nucleus and actin connecting element protein(gene name synonym)|uniprotkb:KASH domain-containing protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652826|imex:IM-16425-64	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	ensembl:ENSP00000344528|ensembl:ENSP00000341781|ensembl:ENST00000358025|ensembl:ENSP00000350719|ensembl:ENST00000458046|ensembl:ENSP00000391937|ensembl:ENST00000555002|ensembl:ENSP00000450831|ensembl:ENST00000341472|refseq:NP_055995.4|refseq:NP_878914.1|refseq:NP_878917.1|refseq:NP_878918.2|dip:DIP-53409N|ensembl:ENSG00000054654(gene)|ensembl:ENST00000344113(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005925"(focal adhesion)|go:"GO:0007097"(nuclear migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR030266|interpro:IPR036872|rcsb pdb:4DXS|rcsb pdb:4FI9|rcsb pdb:6XF1|reactome:R-HSA-1221632|genbank_protein_gi:118918406(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	rogid:wLHWOXR+dUHkcs93g+F2av/9wm49606	intact-crc:A2663AB65AD64336|rigid:v6yW7pSlbrYtxh9u65/NbodlYB8	false	sufficient binding region:1-476	sufficient binding region:6529-6885(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHB9	uniprotkb:Q8IZP0	intact:EBI-1048560|uniprotkb:Q8NCJ4|uniprotkb:Q8WUK2|uniprotkb:B3KUU5|uniprotkb:B3KWY7|uniprotkb:G3V1U4|ensembl:ENSP00000312066	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	psi-mi:srp68_human(display_long)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein(gene name synonym)	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652809|imex:IM-16425-63	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001247431.1|refseq:NP_001247432.1|refseq:NP_055045.2|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|mint:Q9UHB9|rcsb pdb:4P3E|rcsb pdb:4P3F|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:7NFX|reactome:R-HSA-1799339|ensembl:ENSG00000167881(gene)|ensembl:ENST00000307877(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0042493"|go:"GO:0048500"(signal recognition particle)|dip:DIP-50905N|genbank_protein_gi:24497619(identity)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:8WwEMUV+QzJGJ6G7xufvSibYTSY9606	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	intact-crc:9155FD577F1A04B5|rigid:ScbqoLdDwXsx4q88lT/lPymO1bw	false	sufficient binding region:289-627	sufficient binding region:1-476	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IZP0	uniprotkb:Q9BX66	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652792|imex:IM-16425-62	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|genbank_protein_gi:78000162(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606	intact-crc:B35B964256752DC2|rigid:frzoZo2LNNAqa1S95tTN4bu/q2s	false	sufficient binding region:1-476	sufficient binding region:711-1292	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HT8	uniprotkb:Q8IZP0	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652775|imex:IM-16425-61	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|genbank_protein_gi:10834727(identity)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	intact-crc:BA43FFE1B161DF22|rigid:qbVRUS9TIRhslsRY/jKxooLOoOg	false	sufficient binding region:66-127	sufficient binding region:1-476	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y605	uniprotkb:Q8IZP0	intact:EBI-995714|uniprotkb:B3KVT2|ensembl:ENSP00000318352|ensembl:ENSP00000372024|ensembl:ENSP00000422065|uniprotkb:D3DVT3	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	psi-mi:mofa1_human(display_long)|uniprotkb:PGR1(gene name synonym)|uniprotkb:Protein PGR1(gene name synonym)|uniprotkb:Protein associated with MRG of 14 kDa(gene name synonym)|uniprotkb:MRFAP1(gene name)|psi-mi:MRFAP1(display_short)|uniprotkb:PAM14(gene name synonym)	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652758|imex:IM-16425-60	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_150638.1|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR029254|mint:Q9Y605|ensembl:ENSG00000179010(gene)|ensembl:ENST00000320912(transcript)|ensembl:ENST00000382581(transcript)|ensembl:ENST00000507420(transcript)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001258982.1|genbank_protein_gi:50505696(identity)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:qsRG2MjlSzgcyuUj0/45kBNrfw89606	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	intact-crc:2F98CE3644888108|rigid:jE/J/GIDcfPId5JfVlBbKULrnw4	false	sufficient binding region:50-127..127	sufficient binding region:1-476	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y490	uniprotkb:Q8IZP0	intact:EBI-2462036|uniprotkb:A6NMY0|uniprotkb:Q86YD0|uniprotkb:Q9NZQ2|uniprotkb:Q9UHH8|uniprotkb:Q9UPX3|intact:EBI-28967697|ensembl:ENSP00000316029	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	psi-mi:tln1_human(display_long)|uniprotkb:TLN1(gene name)|psi-mi:TLN1(display_short)|uniprotkb:KIAA1027(gene name synonym)|uniprotkb:TLN(gene name synonym)	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652844|imex:IM-16425-65	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000316029|refseq:NP_006280.3|ensembl:ENSG00000137076(gene)|ensembl:ENST00000314888(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:Q9Y490|rcsb pdb:1SYQ|rcsb pdb:2MWN|rcsb pdb:4DJ9|rcsb pdb:6R9T|reactome:R-HSA-114608|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381038|reactome:R-HSA-399955|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|genbank_protein_gi:16753232(identity)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|genbank_protein_gi:61743943(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:C7FGaR2291KB6hBSloee5L8lYgA9606	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	intact-crc:FF629F7856459F57|rigid:Egs7UGjetnz69NhxjAbf5My+l+8	false	sufficient binding region:1678-2541	sufficient binding region:1-476	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21399	uniprotkb:Q00610	intact:EBI-2847111|uniprotkb:Q5VZA7|uniprotkb:Q14652|uniprotkb:D3DRK7|ensembl:ENSP00000309477|ensembl:ENSP00000369255|ensembl:ENSP00000438733	intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00	psi-mi:acohc_human(display_long)|uniprotkb:ACO1(gene name)|psi-mi:ACO1(display_short)|uniprotkb:IREB1(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Ferritin repressor protein(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym)	psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652883|imex:IM-16425-67	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516190.1|refseq:NP_001265281.1|refseq:NP_002188.1|refseq:XP_005251533.1|ensembl:ENSG00000122729(gene)|ensembl:ENST00000309951(transcript)|ensembl:ENST00000379923(transcript)|ensembl:ENST00000541043(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR029784|interpro:IPR036008|interpro:IPR044137|mint:P21399|rcsb pdb:2B3X|rcsb pdb:2B3Y|reactome:R-HSA-917937|go:"GO:0009791"(post-embryonic development)|genbank_protein_gi:8659554(identity)	ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424|genbank_protein_gi:115527063(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hcZPPf3fTfqol8El1L5kwVEljyY9606	rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606	intact-crc:8137017731D4D0E7|rigid:R7HyMV0ZOfRWz0eAP6Ky/piQ/Vo	false	sufficient binding region:1-889	sufficient binding region:1340-1675(IPR000547)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A6NI79	uniprotkb:P21399	intact:EBI-5652866|uniprotkb:A8K9X6|ensembl:ENSP00000347586	intact:EBI-2847111|uniprotkb:Q5VZA7|uniprotkb:Q14652|uniprotkb:D3DRK7|ensembl:ENSP00000309477|ensembl:ENSP00000369255|ensembl:ENSP00000438733	psi-mi:ccd69_human(display_long)|uniprotkb:CCDC69(gene name)|psi-mi:CCDC69(display_short)	psi-mi:acohc_human(display_long)|uniprotkb:ACO1(gene name)|psi-mi:ACO1(display_short)|uniprotkb:IREB1(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Ferritin repressor protein(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652861|imex:IM-16425-66	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056436.2|ensembl:ENSG00000198624(gene)|ensembl:ENST00000355417(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051255"(spindle midzone assembly)|genbank_protein_gi:45935390(identity)	refseq:XP_011516190.1|refseq:NP_001265281.1|refseq:NP_002188.1|refseq:XP_005251533.1|ensembl:ENSG00000122729(gene)|ensembl:ENST00000309951(transcript)|ensembl:ENST00000379923(transcript)|ensembl:ENST00000541043(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR029784|interpro:IPR036008|interpro:IPR044137|mint:P21399|rcsb pdb:2B3X|rcsb pdb:2B3Y|reactome:R-HSA-917937|go:"GO:0009791"(post-embryonic development)|genbank_protein_gi:8659554(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:IC6SaRpdaGLfv9bD8aXbUZY7syU9606	rogid:hcZPPf3fTfqol8El1L5kwVEljyY9606	intact-crc:5DE97E3A8023E83C|rigid:GBcjCvVm5HY2+2JAsQ14Gzo7No4	false	sufficient binding region:57-296	sufficient binding region:1-889	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21399	uniprotkb:P49023	intact:EBI-2847111|uniprotkb:Q5VZA7|uniprotkb:Q14652|uniprotkb:D3DRK7|ensembl:ENSP00000309477|ensembl:ENSP00000369255|ensembl:ENSP00000438733	intact:EBI-702209|uniprotkb:O14970|uniprotkb:O14971|uniprotkb:O60360|uniprotkb:B2RAI3|uniprotkb:Q5HYA4|uniprotkb:B7ZMB4|ensembl:ENSP00000228307	psi-mi:acohc_human(display_long)|uniprotkb:ACO1(gene name)|psi-mi:ACO1(display_short)|uniprotkb:IREB1(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Ferritin repressor protein(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym)	psi-mi:paxi_human(display_long)|uniprotkb:PXN(gene name)|psi-mi:PXN(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652963|imex:IM-16425-71	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516190.1|refseq:NP_001265281.1|refseq:NP_002188.1|refseq:XP_005251533.1|ensembl:ENSG00000122729(gene)|ensembl:ENST00000309951(transcript)|ensembl:ENST00000379923(transcript)|ensembl:ENST00000541043(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR029784|interpro:IPR036008|interpro:IPR044137|mint:P21399|rcsb pdb:2B3X|rcsb pdb:2B3Y|reactome:R-HSA-917937|go:"GO:0009791"(post-embryonic development)|genbank_protein_gi:8659554(identity)	refseq:NP_001074324.1|refseq:NP_002850.2|refseq:NP_079433.3|refseq:NP_001230685.1|refseq:XP_016875232.1|dip:DIP-33851N|ensembl:ENSG00000089159(gene)|ensembl:ENST00000228307(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0038191"(neuropilin binding)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060396"(growth hormone receptor signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001904(Paxillin)|mint:P49023|rcsb pdb:1KKY|rcsb pdb:1KL0|rcsb pdb:1OW6|rcsb pdb:1OW7|rcsb pdb:1OW8|rcsb pdb:2K2R|rcsb pdb:2O9V|rcsb pdb:2VZD|rcsb pdb:2VZG|rcsb pdb:2VZI|rcsb pdb:3GM1|rcsb pdb:3PY7|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3U3F|rcsb pdb:4EDN|rcsb pdb:4R32|rcsb pdb:4XGZ|rcsb pdb:4XH2|rcsb pdb:5UWH|rcsb pdb:6IUI|rcsb pdb:6PW8|rcsb pdb:6U4M|rcsb pdb:6U4N|reactome:R-HSA-180292|reactome:R-HSA-4420097|reactome:R-HSA-445355|reactome:R-HSA-446343|reactome:R-HSA-446388|reactome:R-HSA-8849471|genbank_protein_gi:4506344(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hcZPPf3fTfqol8El1L5kwVEljyY9606	rogid:H8osAQRrVydLfDL97uSSA6Mf6ME9606	intact-crc:A4334ED62F5190AB|rigid:RDhfTg8URI2Pd0RmybQfNs4ZDOM	false	sufficient binding region:1-889	sufficient binding region:288-591	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21399	uniprotkb:P20929	intact:EBI-2847111|uniprotkb:Q5VZA7|uniprotkb:Q14652|uniprotkb:D3DRK7|ensembl:ENSP00000309477|ensembl:ENSP00000369255|ensembl:ENSP00000438733	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:acohc_human(display_long)|uniprotkb:ACO1(gene name)|psi-mi:ACO1(display_short)|uniprotkb:IREB1(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Ferritin repressor protein(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652946|imex:IM-16425-70	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516190.1|refseq:NP_001265281.1|refseq:NP_002188.1|refseq:XP_005251533.1|ensembl:ENSG00000122729(gene)|ensembl:ENST00000309951(transcript)|ensembl:ENST00000379923(transcript)|ensembl:ENST00000541043(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR029784|interpro:IPR036008|interpro:IPR044137|mint:P21399|rcsb pdb:2B3X|rcsb pdb:2B3Y|reactome:R-HSA-917937|go:"GO:0009791"(post-embryonic development)|genbank_protein_gi:8659554(identity)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hcZPPf3fTfqol8El1L5kwVEljyY9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:81D31D652AD772EF|rigid:bjWmwgoUxVJrLdC0mB2/JlHFsws	false	sufficient binding region:1-889	sufficient binding region:4210-6669	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21399	uniprotkb:Q00872	intact:EBI-2847111|uniprotkb:Q5VZA7|uniprotkb:Q14652|uniprotkb:D3DRK7|ensembl:ENSP00000309477|ensembl:ENSP00000369255|ensembl:ENSP00000438733	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:acohc_human(display_long)|uniprotkb:ACO1(gene name)|psi-mi:ACO1(display_short)|uniprotkb:IREB1(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Ferritin repressor protein(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652919|imex:IM-16425-69	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516190.1|refseq:NP_001265281.1|refseq:NP_002188.1|refseq:XP_005251533.1|ensembl:ENSG00000122729(gene)|ensembl:ENST00000309951(transcript)|ensembl:ENST00000379923(transcript)|ensembl:ENST00000541043(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR029784|interpro:IPR036008|interpro:IPR044137|mint:P21399|rcsb pdb:2B3X|rcsb pdb:2B3Y|reactome:R-HSA-917937|go:"GO:0009791"(post-embryonic development)|genbank_protein_gi:8659554(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hcZPPf3fTfqol8El1L5kwVEljyY9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:D56C8622C86759AF|rigid:BykAAXcE76o6NSJ9nWU3T/BwNlU	false	sufficient binding region:1-889	sufficient binding region:727-1141(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q00610	uniprotkb:P21399	intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00	intact:EBI-2847111|uniprotkb:Q5VZA7|uniprotkb:Q14652|uniprotkb:D3DRK7|ensembl:ENSP00000309477|ensembl:ENSP00000369255|ensembl:ENSP00000438733	psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym)	psi-mi:acohc_human(display_long)|uniprotkb:ACO1(gene name)|psi-mi:ACO1(display_short)|uniprotkb:IREB1(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Ferritin repressor protein(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652901|imex:IM-16425-68	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424|genbank_protein_gi:115527063(identity)	refseq:XP_011516190.1|refseq:NP_001265281.1|refseq:NP_002188.1|refseq:XP_005251533.1|ensembl:ENSG00000122729(gene)|ensembl:ENST00000309951(transcript)|ensembl:ENST00000379923(transcript)|ensembl:ENST00000541043(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR029784|interpro:IPR036008|interpro:IPR044137|mint:P21399|rcsb pdb:2B3X|rcsb pdb:2B3Y|reactome:R-HSA-917937|go:"GO:0009791"(post-embryonic development)|genbank_protein_gi:8659554(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606	rogid:hcZPPf3fTfqol8El1L5kwVEljyY9606	intact-crc:778AFECA6B069032|rigid:R7HyMV0ZOfRWz0eAP6Ky/piQ/Vo	false	sufficient binding region:875-1675(IPR000547)	sufficient binding region:1-889	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8T0	uniprotkb:Q96ED9	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	intact:EBI-743290|uniprotkb:O60562|ensembl:ENSP00000380785	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:hook2_human(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653039|imex:IM-16425-75	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	refseq:NP_001093646.1|refseq:NP_037444.2|ensembl:ENSG00000095066(gene)|ensembl:ENST00000397668(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006897"(endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q96ED9|genbank_protein_gi:7019410(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rogid:ryVqr8ZYjAc5SuoRR/zMQxnh0O89606	intact-crc:1BAF978A332C9205|rigid:Rhu5zk+Dn9VvS1rVmsaEBCSNf4c	false	sufficient binding region:1-292	sufficient binding region:525-719	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TDJ6	uniprotkb:Q9H8T0	intact:EBI-5653014|uniprotkb:O94938|uniprotkb:B2RTR3|uniprotkb:B7ZMH3|uniprotkb:F5GWF1|ensembl:ENSP00000251076	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:dmxl2_human(display_long)|uniprotkb:KIAA0856(gene name synonym)|uniprotkb:Rabconnectin-3(gene name synonym)|uniprotkb:DMXL2(gene name)|psi-mi:DMXL2(display_short)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653022|imex:IM-16425-74	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001167587.1|refseq:NP_056078.2|refseq:NP_001167588.1|ensembl:ENSG00000104093(gene)|ensembl:ENST00000251076(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043291"(RAVE complex)|go:"GO:0098992"(neuronal dense core vesicle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022033|interpro:IPR036322|genbank_protein_gi:119120893(identity)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RytycxvrFz8wabGFVQf7f2WJMr09606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	intact-crc:44CD48A221E344F6|rigid:lMU20pfmiUeRBaljgb2oK9ylkIY	false	sufficient binding region:2454-3036	sufficient binding region:1-292	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35609	uniprotkb:Q9H8T0	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652997|imex:IM-16425-73	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	intact-crc:910234B02DDF14AE|rigid:ACnLmJFm0Vk5QLkjqFDGC/u/6oM	false	sufficient binding region:477-894	sufficient binding region:1-292	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8T0	uniprotkb:P35609	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5652980|imex:IM-16425-72	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	intact-crc:36E333B6FB7986CE|rigid:ACnLmJFm0Vk5QLkjqFDGC/u/6oM	false	sufficient binding region:1-292	sufficient binding region:1-894	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VU43	uniprotkb:Q9H8T0	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653108|imex:IM-16425-79	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|genbank_protein_gi:50658072(identity)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	intact-crc:6B3F42AFA2006807|rigid:YPqhOFCZpbJzwPtpD+BJFOz6a6M	false	sufficient binding region:25-2346	sufficient binding region:1-292	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8T0	uniprotkb:P20929	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653091|imex:IM-16425-78	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:863568E9E3643802|rigid:FHi60t2mjQITfXUC629KnJiH3K0	false	sufficient binding region:1-292	sufficient binding region:4189-6669	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8T0	uniprotkb:O43318	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653074|imex:IM-16425-77	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0008349"(MAP kinase kinase kinase kinase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|ensembl:ENSG00000135341(gene)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|ensembl:ENST00000369329(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017421(Mitogen-activated protein kinase kinase kinase 7)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27523N|genbank_protein_gi:21735560(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606	intact-crc:14A4C096DC36CB2F|rigid:AO8MfAz2E33DTDD/Te6CbsNvOLw	false	sufficient binding region:1-292	sufficient binding region:454-606	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86VS8	uniprotkb:Q9H8T0	intact:EBI-1777078|uniprotkb:Q8NBH0|uniprotkb:Q9BY13|uniprotkb:D3DSY8|ensembl:ENSP00000305699	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:hook3_human(display_long)|uniprotkb:HOOK3(gene name)|psi-mi:HOOK3(display_short)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653056|imex:IM-16425-76	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115786.1|ensembl:ENSG00000168172(gene)|ensembl:ENST00000307602(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|rcsb pdb:5J8E|rcsb pdb:6B9H|go:"GO:0034454"(microtubule anchoring at centrosome)|genbank_protein_gi:33356164(identity)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hzM38dyr89rY7z71px9K4rVNL6s9606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	intact-crc:A85FD361FBEC6245|rigid:AarBTelkmM5UM6nI1rUfBmfWZng	false	sufficient binding region:573-718(IPR008636)	sufficient binding region:1-292	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q4VCS5	uniprotkb:Q00872	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653177|imex:IM-16425-83	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:999DB1CF1CDB0858|rigid:YbmdIXAWPyzpxBBmyXxe4Wu1vpE	false	sufficient binding region:410-1084	sufficient binding region:827-1141(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HAU5	uniprotkb:Q9H8T0	intact:EBI-372073|uniprotkb:A6NLJ5|uniprotkb:Q5W0J4|uniprotkb:Q14BM1|uniprotkb:Q8N8U1|uniprotkb:Q9H1J2|uniprotkb:Q9NWL1|uniprotkb:Q9P2D9|uniprotkb:Q9Y4M9|uniprotkb:D3DRS0|intact:EBI-28979373|ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:rent2_human(display_long)|uniprotkb:Nonsense mRNA reducing factor 2(gene name synonym)|uniprotkb:Up-frameshift suppressor 2 homolog(gene name synonym)|uniprotkb:UPF2(gene name)|psi-mi:UPF2(display_short)|uniprotkb:KIAA1408(gene name synonym)|uniprotkb:RENT2(gene name synonym)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653160|imex:IM-16425-82	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENSG00000151461(gene)|ensembl:ENST00000356352(transcript)|ensembl:ENST00000357604(transcript)|ensembl:ENST00000397053(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR007193(Up-frameshift suppressor 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039762|mint:Q9HAU5|rcsb pdb:1UW4|rcsb pdb:2WJV|rcsb pdb:4CEK|rcsb pdb:4CEM|dip:DIP-31148N|refseq:NP_056357.1|refseq:NP_542166.1|genbank_protein_gi:18375674(identity)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:+hTMzl+IgYWyiDMSv5s4TeGt3D89606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	intact-crc:EE5DFDA75A558E29|rigid:xaWOlzFrJiGolfj3onkBSJkoh4U	false	sufficient binding region:388-1272	sufficient binding region:1-292	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14827	uniprotkb:Q9H8T0	intact:EBI-1055500|uniprotkb:Q9UK56|intact:EBI-1058320|uniprotkb:B9EG89|ensembl:ENSP00000265080	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:rgrf2_human(display_long)|uniprotkb:GRF2(gene name synonym)|uniprotkb:Ras guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RASGRF2(gene name)|psi-mi:RASGRF2(display_short)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653142|imex:IM-16425-81	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008840.1|ensembl:ENSG00000113319(gene)|ensembl:ENST00000265080(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR030744|interpro:IPR035899|interpro:IPR036964|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|genbank_protein_gi:38373676(identity)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:SP64p7eTQmRlLm1WGt5yEdUhAWE9606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	intact-crc:BE1A9A99F13FC36B|rigid:PR2ZsbVs6nLnXkLFzv0oJLnQklw	false	sufficient binding region:614-1237(IPR000651)	sufficient binding region:1-292	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8T0	uniprotkb:Q5VU43	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653125|imex:IM-16425-80	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:61743932(identity)	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|genbank_protein_gi:50658072(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	intact-crc:8A77B079EF2D3AC6|rigid:YPqhOFCZpbJzwPtpD+BJFOz6a6M	false	sufficient binding region:1-292	sufficient binding region:615-2346	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35240	uniprotkb:Q4VCS5	intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym)	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653253|imex:IM-16425-86	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N|genbank_protein_gi:32967259(identity)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	intact-crc:89D4101959AB69CD|rigid:wZslmhsGtzulnsSwXb6eNfxNNvc	false	sufficient binding region:444-595	sufficient binding region:410-1084	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VTT5	uniprotkb:Q4VCS5	intact:EBI-5653225|uniprotkb:Q8NA11|uniprotkb:Q6AWC0|uniprotkb:Q6ZRG7|uniprotkb:A6NF75|uniprotkb:Q7Z3G9|uniprotkb:Q6AWC1|uniprotkb:Q96C54|uniprotkb:Q6NXF9|uniprotkb:Q5VTT6|ensembl:ENSP00000363557	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	psi-mi:myom3_human(display_long)|uniprotkb:Myomesin family member 3(gene name synonym)|uniprotkb:MYOM3(gene name)|psi-mi:MYOM3(display_short)	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653220|imex:IM-16425-85	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689585.3|ensembl:ENSG00000142661(gene)|ensembl:ENST00000374434(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0031430"(M band)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|genbank_protein_gi:40255105(identity)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3cBvAjX/bvUZPzI1J3zRE05/vTk9606	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	intact-crc:8781311BF90BA9C8|rigid:GYpTPPAqXM+dAFhrMGMNETZLT2Q	false	sufficient binding region:1-1437(IPR003599)	sufficient binding region:410-1084	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q4VCS5	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653195|imex:IM-16425-84	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	intact-crc:4CCB8726DCBEDAE7|rigid:UJAcqGjknyvHIpjjtBFqOJDujfI	false	sufficient binding region:917-1141(IPR003961)	sufficient binding region:410-1084	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q4VCS5	uniprotkb:P10827	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	intact:EBI-286285|uniprotkb:P21205|uniprotkb:Q8N6A1|uniprotkb:Q96H73|uniprotkb:A8K3B5|ensembl:ENSP00000264637|ensembl:ENSP00000377679	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:tha_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:EAR7(gene name synonym)|uniprotkb:c-erbA-1(gene name synonym)|uniprotkb:c-erbA-alpha(gene name synonym)|uniprotkb:THRA(gene name)|psi-mi:THRA(display_short)|uniprotkb:ERBA1(gene name synonym)|uniprotkb:NR1A1(gene name synonym)|uniprotkb:THRA1(gene name synonym)|uniprotkb:THRA2(gene name synonym)|uniprotkb:V-erbA-related protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653325|imex:IM-16425-90	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	refseq:NP_001177847.1|refseq:NP_001177848.1|refseq:NP_003241.2|refseq:NP_955366.1|dip:DIP-31452N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007611"(learning or memory)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008050"(female courtship behavior)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009409"(response to cold)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033032"(regulation of myeloid cell apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000143"(negative regulation of DNA-templated transcription, initiation)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1NAV|rcsb pdb:2H77|rcsb pdb:2H79|rcsb pdb:3HZF|rcsb pdb:3ILZ|rcsb pdb:3JZB|rcsb pdb:4LNW|rcsb pdb:4LNX|reactome:R-HSA-383280|reactome:R-HSA-4090294|ensembl:ENSG00000126351(gene)|ensembl:ENST00000264637(transcript)|ensembl:ENST00000394121(transcript)|genbank_protein_gi:537519(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	rogid:u1B3u6XbEyC3OKOWr25s9qZYe4o9606	intact-crc:BD4B4FC714ECC3FD|rigid:fQSB/42mZb5R9k4Koz7ZEX5KsMI	false	sufficient binding region:410-1084	sufficient binding region:1-490	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q4VCS5	uniprotkb:O14544	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	intact:EBI-3929549|uniprotkb:Q8WUM3|ensembl:ENSP00000381034|ensembl:ENSP00000463395	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:socs6_human(display_long)|uniprotkb:SOCS6(gene name)|psi-mi:SOCS6(display_short)|uniprotkb:CIS4(gene name synonym)|uniprotkb:SOCS4(gene name synonym)|uniprotkb:Cytokine-inducible SH2 protein 4(gene name synonym)|uniprotkb:Suppressor of cytokine signaling 4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653308|imex:IM-16425-89	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	interpro:IPR037345|mint:O14544|rcsb pdb:2VIF|reactome:R-HSA-1433559|reactome:R-HSA-8951664|reactome:R-HSA-9706369|interpro:IPR036860|ensembl:ENSG00000170677(gene)|ensembl:ENST00000397942(transcript)|ensembl:ENST00000582322(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0050868"(negative regulation of T cell activation)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028421|interpro:IPR035865|interpro:IPR036036|refseq:NP_004223.2|refseq:XP_005266840.1|refseq:XP_016881575.1|refseq:XP_016881576.1|genbank_protein_gi:118402588(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	rogid:O++hp+HHhT2m2QNupHdNfK5DBqQ9606	intact-crc:30C5B537D3B080F7|rigid:T5b0KU+gkGqivrAHg8zUNXiK2E0	false	sufficient binding region:410-1084	sufficient binding region:251-535	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14683	uniprotkb:Q4VCS5	intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym)	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653289|imex:IM-16425-88	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N|genbank_protein_gi:30581134(identity)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	intact-crc:73D578568618A257|rigid:k6/quPDgaNKJaNW74NQZ15l545Y	false	sufficient binding region:902-1233(IPR003439)	sufficient binding region:410-1084	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q4VCS5	uniprotkb:O00443	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	intact:EBI-641094|ensembl:ENSP00000265970|uniprotkb:Q14CQ9|uniprotkb:B4E2G4|uniprotkb:B0LPH2	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:p3c2a_human(display_long)|uniprotkb:Phosphoinositide 3-kinase-C2-alpha(gene name synonym)|uniprotkb:PIK3C2A(gene name)|psi-mi:PIK3C2A(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653270|imex:IM-16425-87	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	ensembl:ENSG00000011405(gene)|ensembl:ENST00000265970(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0016020"(membrane)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016477"(cell migration)|go:"GO:0006887"(exocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|refseq:NP_001308307.1|refseq:XP_016873413.1|refseq:NP_002636.2|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0061024"(membrane organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR001683(Phox-like)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036871|interpro:IPR036940|interpro:IPR037705|interpro:IPR042133|interpro:IPR042236|rcsb pdb:2AR5|rcsb pdb:2IWL|rcsb pdb:2REA|rcsb pdb:2RED|rcsb pdb:6BTY|rcsb pdb:6BTZ|rcsb pdb:6BU0|rcsb pdb:6BUB|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-432722|reactome:R-HSA-8856828|dip:DIP-33727N|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|genbank_protein_gi:4505798(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	rogid:etm4OwWiGBZtmarHi94o8yW9js89606	intact-crc:630C76659E3326C6|rigid:oi5STTW0q3zIJB1rYunIITi4qs0	false	sufficient binding region:410-1084	sufficient binding region:1404-1686(IPR000008)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52566	uniprotkb:Q15327	intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945|ensembl:ENSP00000440560|ensembl:ENSP00000444860	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short)	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653383|imex:IM-16425-93	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166.3|ensembl:ENSG00000111348(gene)|ensembl:ENST00000541546(transcript)|ensembl:ENST00000541644(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071461"(cellular response to redox state)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|ensembl:ENST00000228945(transcript)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|dip:DIP-40959N|genbank_protein_gi:404044(identity)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	intact-crc:A993895A56539D6F|rigid:O3t9wi0/ixClwkPi6NclmJzUz6o	false	sufficient binding region:20-201(IPR000406)	sufficient binding region:1-319	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q4VCS5	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653361|imex:IM-16425-92	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	intact-crc:118C725A5279A672|rigid:4gH1oOYPjLY0Hqv+ONNiPTAKYIo	false	sufficient binding region:32319-34350	sufficient binding region:410-1084	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q4VCS5	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653342|imex:IM-16425-91	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	intact-crc:55D8AACC74D70B25|rigid:4gH1oOYPjLY0Hqv+ONNiPTAKYIo	false	sufficient binding region:29536-34350(IPR003961)	sufficient binding region:410-1084	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15327	uniprotkb:P05976	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	intact:EBI-5653459|uniprotkb:Q6IBD5|uniprotkb:B2R4T6|uniprotkb:B2R4N6|uniprotkb:P06741|ensembl:ENSP00000307280	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:myl1_human(display_long)|uniprotkb:Myosin light chain alkali 1/2(gene name synonym)|uniprotkb:MYL1(gene name)|psi-mi:MYL1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653454|imex:IM-16425-97	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	refseq:NP_524144.1|refseq:NP_524146.1|ensembl:ENSG00000168530(gene)|ensembl:ENST00000352451(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|reactome:R-HSA-390522|genbank_protein_gi:115527084(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	rogid:72brLz+Ng+6/SNJzDACVhzOVdIY9606	intact-crc:F63682D436372943|rigid:ykEfCQ/2fmYwBKyoK+yc9Bug2Xs	false	sufficient binding region:1-319	sufficient binding region:188-194..194(IPR002048)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15327	uniprotkb:Q00872	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653436|imex:IM-16425-96	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:F99415C09F734B13|rigid:NyrTW5uelp7pVUvlth6NHG/pMZs	false	sufficient binding region:1-319	sufficient binding region:716-1141(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15327	uniprotkb:P42704	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653419|imex:IM-16425-95	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N|genbank_protein_gi:31621305(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606	intact-crc:598308F602E53166|rigid:g3mfikUbe2FiIJ3CdjFV65zQEjc	false	sufficient binding region:1-319	sufficient binding region:793-1394	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15327	uniprotkb:Q03001	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653401|imex:IM-16425-94	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	intact-crc:290936B28B1789D6|rigid:RVPHtw0MERj31Dom97owSQr3IWQ	false	sufficient binding region:1-319	sufficient binding region:3174-7570(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q15327	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653533|imex:IM-16425-101	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	intact-crc:719C486F0A107358|rigid:k4oKfWHhwcuFucdkTmeiRHhMNnQ	false	sufficient binding region:130-442(IPR000007)	sufficient binding region:1-319	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15327	uniprotkb:Q8WZ42	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653515|imex:IM-16425-100	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:737BF3787164F996|rigid:8d0goQl2DSRQwhfP7D69KAwEMRU	false	sufficient binding region:1-319	sufficient binding region:8574-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15327	uniprotkb:Q96D71	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	intact:EBI-1171195|uniprotkb:Q9BXY9|uniprotkb:Q8NDR7|uniprotkb:Q8WU62|uniprotkb:Q5JWJ7|uniprotkb:Q5JWJ5|uniprotkb:Q5JWJ6|uniprotkb:B7ZBZ8|uniprotkb:B7ZBZ9|uniprotkb:B7ZC00|uniprotkb:J3KP76|intact:EBI-28972584|ensembl:ENSP00000392065	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:reps1_human(display_long)|uniprotkb:REPS1(gene name)|psi-mi:REPS1(display_short)|uniprotkb:RalBP1-interacting protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653498|imex:IM-16425-99	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	refseq:NP_001273540.1|refseq:NP_001273541.1|ensembl:ENSP00000258062|ensembl:ENST00000367663|ensembl:ENSP00000356635|ensembl:ENST00000409812|ensembl:ENSP00000386699|ensembl:ENSP00000392065|ensembl:ENST00000258062|refseq:NP_001122089.1|refseq:NP_114128.3|ensembl:ENSG00000135597(gene)|ensembl:ENST00000450536(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814|mint:Q96D71|reactome:R-HSA-8856825|reactome:R-HSA-8856828|genbank_protein_gi:39645197(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	rogid:3MDo2J3yQfEm6X0eRAutKvrg+Fo9606	intact-crc:463974ED80431219|rigid:Qp3zxYRDs4+ny8Mf6MVLfeWyE6Y	false	sufficient binding region:1-319	sufficient binding region:514-796	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54296	uniprotkb:Q15327	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653480|imex:IM-16425-98	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:31418211(identity)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	intact-crc:F1F852C66BCD1567|rigid:tWgNEA3uPkyT3MYa5680VpGKlA8	false	sufficient binding region:910-1465(IPR003599)	sufficient binding region:1-319	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01484	uniprotkb:O15084	intact:EBI-941975|uniprotkb:Q01485|uniprotkb:Q08AC7|uniprotkb:Q08AC8|uniprotkb:Q7Z3L5|ensembl:ENSP00000349588	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:ank2_human(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653586|imex:IM-16425-104	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120965.1|refseq:NP_001139.3|refseq:NP_066187.2|dip:DIP-37425N|ensembl:ENSG00000145362(gene)|ensembl:ENST00000357077(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003283"(atrial septum development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745|mint:Q01484|rcsb pdb:4D8O|rcsb pdb:4RLV|rcsb pdb:4RLY|rcsb pdb:5Y4D|rcsb pdb:5Y4E|rcsb pdb:5Y4F|rcsb pdb:5YIR|rcsb pdb:5YIS|rcsb pdb:6KZJ|rcsb pdb:6M3Q|reactome:R-HSA-445095|reactome:R-HSA-6807878|genbank_protein_gi:52426734(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wHoFDw3CIP2xOUZj9WzEMGm/z8k9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:8642C38D2FC74D92|rigid:ssGKTKLlftWgVqNo0WAcSqpG0zw	false	sufficient binding region:?-?	sufficient binding region:42-693	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01484	uniprotkb:O15084	intact:EBI-941975|uniprotkb:Q01485|uniprotkb:Q08AC7|uniprotkb:Q08AC8|uniprotkb:Q7Z3L5|ensembl:ENSP00000349588	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:ank2_human(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653569|imex:IM-16425-103	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120965.1|refseq:NP_001139.3|refseq:NP_066187.2|dip:DIP-37425N|ensembl:ENSG00000145362(gene)|ensembl:ENST00000357077(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003283"(atrial septum development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745|mint:Q01484|rcsb pdb:4D8O|rcsb pdb:4RLV|rcsb pdb:4RLY|rcsb pdb:5Y4D|rcsb pdb:5Y4E|rcsb pdb:5Y4F|rcsb pdb:5YIR|rcsb pdb:5YIS|rcsb pdb:6KZJ|rcsb pdb:6M3Q|reactome:R-HSA-445095|reactome:R-HSA-6807878|genbank_protein_gi:52426734(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wHoFDw3CIP2xOUZj9WzEMGm/z8k9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:31F6C63E7798DE57|rigid:ssGKTKLlftWgVqNo0WAcSqpG0zw	false	sufficient binding region:?-?	sufficient binding region:42-693	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UG63	uniprotkb:O15084	intact:EBI-2959697|ensembl:ENSP00000287844|uniprotkb:Q96TE8|uniprotkb:O60864|uniprotkb:Q75MJ0|uniprotkb:Q75MJ1	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:abcf2_human(display_long)|uniprotkb:ABCF2(gene name)|psi-mi:ABCF2(display_short)|uniprotkb:Iron-inhibited ABC transporter 2(gene name synonym)|uniprotkb:HUSSY-18(orf name)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653551|imex:IM-16425-102	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000033050(gene)|ensembl:ENST00000287844(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|mint:Q9UG63|go:"GO:0016020"(membrane)|refseq:NP_005683.2|refseq:NP_009120.1|refseq:XP_016867128.1|refseq:XP_016867129.1|genbank_protein_gi:27881504(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:TdGWfZ4OYohgxKLL1uyz7X+FWmQ9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:6EBBBF2B61B11D20|rigid:usilj6OaOGLmc7nMJNpCcqJNFJw	false	sufficient binding region:325-623(IPR003593)	sufficient binding region:42-693	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:O15084	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653637|imex:IM-16425-107	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:68131556(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:2A243981404D9698|rigid:KHY2mJenj9I+DPzAP3EXOKgMAOc	false	sufficient binding region:42-693	sufficient binding region:151-1053	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UPS8	uniprotkb:O15084	intact:EBI-3946096|ensembl:ENSP00000365255|uniprotkb:A6NH29|uniprotkb:Q2TAZ3|uniprotkb:Q6ZR14|uniprotkb:Q9H1Q1|uniprotkb:Q9NSK9|uniprotkb:Q9NTD5|uniprotkb:Q9NW69	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:anr26_human(display_long)|uniprotkb:ANKRD26(gene name)|psi-mi:ANKRD26(display_short)|uniprotkb:KIAA1074(gene name synonym)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653620|imex:IM-16425-106	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107890(gene)|ensembl:ENST00000376087(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0045599"(negative regulation of fat cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021885|interpro:IPR036770|interpro:IPR039497|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001242982.1|refseq:NP_055730.2|genbank_protein_gi:7662473(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/09/18	rogid:54QEd9o6qSv6cl/C8q8zWRnGZhw9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:336228A48BE091B5|rigid:lJ938SPz/o6cLPPQcT5vGkTMy2c	false	sufficient binding region:88-c	sufficient binding region:42-693	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:Q9P2R3	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-2513908|uniprotkb:Q5RKV4|uniprotkb:Q9ULG5|uniprotkb:A8KA65|intact:EBI-2838972|intact:EBI-2948552|ensembl:ENSP00000343362|ensembl:ENSP00000497187	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:anfy1_human(display_long)|uniprotkb:Ankyrin repeat and FYVE domain-containing protein 1(gene name synonym)|uniprotkb:ANKFY1(gene name)|psi-mi:ANKFY1(display_short)|uniprotkb:ANKHZN(gene name synonym)|uniprotkb:KIAA1255(gene name synonym)|uniprotkb:Ankyrin repeats hooked to a zinc finger motif(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653603|imex:IM-16425-105	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_057460.3|refseq:NP_001316992.1|refseq:NP_001244928.1|dip:DIP-46068N|ensembl:ENSG00000185722(gene)|ensembl:ENST00000341657(transcript)|ensembl:ENST00000648043(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044354"(macropinosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-9013405|genbank_protein_gi:110815812(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:237ungtRc80jqTOKBUnFX9qDUGw9606	intact-crc:72ACF7DEE233E1D3|rigid:XkY0YXdjHLz67PNF5+6OJmruU98	false	sufficient binding region:42-693	sufficient binding region:269-1169	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:Q04900	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-2115896|uniprotkb:Q5JSU6|uniprotkb:E1P5E8|uniprotkb:E1P5E7|uniprotkb:E1P5E9|uniprotkb:B4DQ85|uniprotkb:O95413|uniprotkb:Q9BPV0|uniprotkb:Q9NR26|ensembl:ENSP00000309376	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:muc24_human(display_long)|uniprotkb:Endolyn(gene name synonym)|uniprotkb:CD164(gene name)|psi-mi:CD164(display_short)|uniprotkb:Multi-glycosylated core protein 24(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653713|imex:IM-16425-111	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_001135873.1|refseq:NP_001135874.1|refseq:NP_001135875.1|refseq:NP_001135876.1|refseq:NP_006007.2|refseq:NP_001333429.1|dip:DIP-43970N|ensembl:ENSG00000135535(gene)|ensembl:ENST00000310786(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR007947(CD164 related protein)|mint:Q04900|genbank_protein_gi:34222157(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:RnECOHDDKJ98oN/MPUzPHIwRePs9606	intact-crc:12D17BDA040AB0DD|rigid:pWeVkKbpjdoKmSenO9wTj6EWZkk	false	sufficient binding region:42-693	sufficient binding region:47-197(IPR007947)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:P20749	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-958997|ensembl:ENSP00000164227	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:bcl3_human(display_long)|uniprotkb:BCL3(gene name)|psi-mi:BCL3(display_short)|uniprotkb:BCL4(gene name synonym)|uniprotkb:D19S37(gene name synonym)|uniprotkb:Proto-oncogene BCL3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653696|imex:IM-16425-110	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_005169.2|ensembl:ENSG00000069399(gene)|ensembl:ENST00000164227(transcript)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0002467"(germinal center formation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010225"(response to UV-C)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030496"(midbody)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032996"(Bcl3-Bcl10 complex)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048536"(spleen development)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P20749|rcsb pdb:1K1A|rcsb pdb:1K1B|genbank_protein_gi:20336471(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:VqvziEG5TBZUct1eoVx6AoHRjhQ9606	intact-crc:C158C6155CDCF6CD|rigid:XSzS1MhfPihZjx74tPjVoLk2mxI	false	sufficient binding region:42-693	sufficient binding region:174-454	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9ULJ7	uniprotkb:O15084	intact:EBI-5653671|uniprotkb:Q6N064|uniprotkb:A8K4V3|uniprotkb:Q6ZSE6|uniprotkb:B4DHJ6|uniprotkb:E9PDW0|ensembl:ENSP00000425658	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:anr50_human(display_long)|uniprotkb:KIAA1223(gene name synonym)|uniprotkb:ANKRD50(gene name)|psi-mi:ANKRD50(display_short)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653679|imex:IM-16425-109	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-47302N|refseq:NP_001161354.1|refseq:NP_065070.1|refseq:XP_016863960.1|ensembl:ENSG00000151458(gene)|ensembl:ENST00000504087(transcript)|go:"GO:0005768"(endosome)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q9ULJ7|genbank_protein_gi:62988327(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:cP1xkkSlKwersPLj/gvrnWOjm+89606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:F14C7D788CF7597D|rigid:ZPFmYecmtU7RQzzDEDigCw/oa64	false	sufficient binding region:693-1429..1429	sufficient binding region:42-693	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:O15084	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653654|imex:IM-16425-108	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:68131556(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:597C0FA2691AE8B1|rigid:KHY2mJenj9I+DPzAP3EXOKgMAOc	false	sufficient binding region:821-1053	sufficient binding region:42-693	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:P61978	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653766|imex:IM-16425-114	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N|genbank_protein_gi:14165436(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	intact-crc:F651CAC15BD1C52A|rigid:SExqlzfmJ/9LxnneraYoErO0Ss0	false	sufficient binding region:42-693	sufficient binding region:330-463	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:Q96KQ7	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653749|imex:IM-16425-113	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|genbank_protein_gi:18426878(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606	intact-crc:69B8611C0A30F570|rigid:Zmx4c5KRRcTt/pjtkjNUfIT98y8	false	sufficient binding region:42-693	sufficient binding region:659-1210	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:P26641	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653731|imex:IM-16425-112	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|genbank_protein_gi:83656774(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:21201F083E905898|rigid:cCBYf/jcPLwxwGHWeLDdcuchn3k	false	sufficient binding region:42-693	sufficient binding region:258-437(IPR001662)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UM47	uniprotkb:O15084	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653835|imex:IM-16425-118	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000426.2|ensembl:ENSP00000263388|dip:DIP-39827N|ensembl:ENSG00000074181(gene)|ensembl:ENST00000263388(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0050793"(regulation of developmental process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802|genbank_protein_gi:4557798(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:E31A747F8E24B44F|rigid:k2dlavSEvuGJ3WB05v1lfKnArIk	false	sufficient binding region:1810-2321	sufficient binding region:42-693	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:Q04721	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-2652733|uniprotkb:Q5T3X7|uniprotkb:Q99734|uniprotkb:Q9H240|ensembl:ENSP00000256646	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:notc2_human(display_long)|uniprotkb:NOTCH2(gene name)|psi-mi:NOTCH2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653818|imex:IM-16425-117	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_001186930.1|refseq:NP_077719.2|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046849"(bone remodeling)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0072014"(proximal tubule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072104"(glomerular capillary formation)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:1990705"(cholangiocyte proliferation)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001204"(regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|go:"GO:0035622"(intrahepatic bile duct development)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022336|interpro:IPR010660(Notch, NOD region)|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q04721|rcsb pdb:2OO4|rcsb pdb:5MWB|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-2197563|reactome:R-HSA-2979096|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013695|ensembl:ENSG00000134250(gene)|ensembl:ENST00000256646(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001947"(heart looping)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035264"(multicellular organism growth)|genbank_protein_gi:24041034(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:aXdQSGMwNJ7K0tA2kc3rRFysbIc9606	intact-crc:0874698DC91390C8|rigid:LK52NEXD9+6VAMBuTrn5M550oKk	false	sufficient binding region:42-693	sufficient binding region:1966-2471	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:P52179	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-5353249|uniprotkb:Q14BD6|uniprotkb:Q6H969|uniprotkb:Q6ZUU0|ensembl:ENSP00000348821	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:myom1_human(display_long)|uniprotkb:MYOM1(gene name)|psi-mi:MYOM1(display_short)|uniprotkb:190 kDa connectin-associated protein(gene name synonym)|uniprotkb:190 kDa titin-associated protein(gene name synonym)|uniprotkb:Myomesin family member 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653800|imex:IM-16425-116	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	dip:DIP-59649N|refseq:NP_003794.3|refseq:NP_062830.1|ensembl:ENSG00000101605(gene)|ensembl:ENST00000356443(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P52179|rcsb pdb:2R15|rcsb pdb:2Y23|rcsb pdb:2Y25|rcsb pdb:3RBS|rcsb pdb:5FM4|rcsb pdb:5FM5|rcsb pdb:5FM8|rcsb pdb:6T3O|genbank_protein_gi:46249363(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:5lfd5o+54eyer647zxvU0LX1wpM9606	intact-crc:587DF13D514A3E75|rigid:Sg/Kgx1RQWvM5Us3x/YKXo4mNIg	false	sufficient binding region:42-693	sufficient binding region:1098-1685(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:O43390	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653783|imex:IM-16425-115	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1|genbank_protein_gi:14141188(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606	intact-crc:A215C35C18CE0591|rigid:r7r17aUVlNCdBBej1Nxbvtk1CsY	false	sufficient binding region:42-693	sufficient binding region:413-633	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:O95271	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-1105254|uniprotkb:O95272|uniprotkb:Q4G0F2|intact:EBI-28985643|ensembl:ENSP00000311579	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:tnks1_human(display_long)|uniprotkb:TNKS(gene name)|psi-mi:TNKS(display_short)|uniprotkb:PARP5A(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:TIN1(gene name synonym)|uniprotkb:TINF1(gene name synonym)|uniprotkb:TNKS1(gene name synonym)|uniprotkb:Tankyrase I(gene name synonym)|uniprotkb:TNKS-1(gene name synonym)|uniprotkb:TRF1-interacting ankyrin-related ADP-ribose polymerase(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 5A(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 5(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase-1(gene name synonym)|uniprotkb:Tankyrase-1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653887|imex:IM-16425-121	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_003738.2|rcsb pdb:5JHQ|rcsb pdb:5JTI|rcsb pdb:5JU5|rcsb pdb:5KNI|rcsb pdb:6QXU|rcsb pdb:6URQ|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-5545619|reactome:R-HSA-5689880|reactome:R-HSA-8948751|rcsb pdb:5GP7|ensembl:ENSP00000311579|ensembl:ENSG00000173273(gene)|ensembl:ENST00000310430(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051028"(mRNA transport)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904743"(negative regulation of telomeric DNA binding)|go:"GO:1904908"(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR028731|interpro:IPR036770|mint:O95271|rcsb pdb:2RF5|rcsb pdb:3UDD|rcsb pdb:3UH2|rcsb pdb:3UH4|rcsb pdb:4DVI|rcsb pdb:4I9I|go:"GO:0016055"(Wnt signaling pathway)|rcsb pdb:4K4F|rcsb pdb:4KRS|rcsb pdb:4LI6|rcsb pdb:4LI7|rcsb pdb:4LI8|rcsb pdb:4MSG|rcsb pdb:4MSK|rcsb pdb:4MT9|rcsb pdb:4N3R|rcsb pdb:4N4V|rcsb pdb:4OA7|rcsb pdb:4TOR|rcsb pdb:4TOS|rcsb pdb:4U6A|rcsb pdb:4UUH|rcsb pdb:4UW1|rcsb pdb:4K4E|rcsb pdb:4W5S|rcsb pdb:4W6E|rcsb pdb:5EBT|rcsb pdb:5ECE|rcsb pdb:5ETY|dip:DIP-36652N|genbank_protein_gi:87239980(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:0WKEfg5OMAISQutoJb2w+hBfmOU9606	intact-crc:887DD753C163DF3E|rigid:fcH7qp9eXmDnW6RCLSAn0QBraOE	false	sufficient binding region:42-693	sufficient binding region:381-1327	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96RS0	uniprotkb:O15084	intact:EBI-949244|ensembl:ENSP00000260129|uniprotkb:A6NJQ5|uniprotkb:Q5GH23|uniprotkb:Q8TDG9|uniprotkb:Q96QU3|uniprotkb:Q9H5V3|intact:EBI-2563555	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:tgs1_human(display_long)|uniprotkb:Cap-specific guanine-N2 methyltransferase(gene name synonym)|uniprotkb:Nuclear receptor coactivator 6-interacting protein(gene name synonym)|uniprotkb:PRIP-interacting protein with methyltransferase motif(gene name synonym)|uniprotkb:CLL-associated antigen KW-2(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 137(gene name synonym)|uniprotkb:TGS1(gene name)|psi-mi:TGS1(display_short)|uniprotkb:PIMT(gene name synonym)|uniprotkb:HCA137(gene name synonym)|uniprotkb:NCOA6IP(gene name synonym)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653870|imex:IM-16425-120	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137574(gene)|ensembl:ENST00000260129(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009452"(7-methylguanosine RNA capping)|go:"GO:0015030"(Cajal body)|go:"GO:0022613"(ribonucleoprotein complex biogenesis)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0036261"(7-methylguanosine cap hypermethylation)|go:"GO:0071164"(RNA trimethylguanosine synthase activity)|interpro:IPR019012|interpro:IPR029063|rcsb pdb:3EGI|rcsb pdb:3GDH|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-191859|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:NP_079107.6|refseq:NP_001304831.1|dip:DIP-49970N|genbank_protein_gi:15077007(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:K72Uc4b54997Kq/gZWB5NMPfLVk9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:7B9860BC5DBEB47A|rigid:VKQYqL/ZC947po4X609nyPQmzcA	false	sufficient binding region:1-853	sufficient binding region:42-693	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:Q9Y3C5	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653852|imex:IM-16425-119	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5|genbank_protein_gi:34452682(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	intact-crc:A08733D1AD282CD0|rigid:Bm4vYxxAP5mfkvxAKFrn0q9R0UI	false	sufficient binding region:42-693	sufficient binding region:118-154..154(IPR001841)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O15084	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653955|imex:IM-16425-125	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349720(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:446F3F8EF5A1B565|rigid:FYZT5/Hk1S8WR1Yqn6bfSRPRY48	false	sufficient binding region:5006-34350	sufficient binding region:42-693	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:Q9H2K2	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-4398527|uniprotkb:Q9H8F2|uniprotkb:Q9HAS4|uniprotkb:B2RBD3|ensembl:ENSP00000360689	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:tnks2_human(display_long)|uniprotkb:TNKS2(gene name)|psi-mi:TNKS2(display_short)|uniprotkb:PARP5B(gene name synonym)|uniprotkb:TANK2(gene name synonym)|uniprotkb:TNKL(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 5B(gene name synonym)|uniprotkb:TNKS-2(gene name synonym)|uniprotkb:TRF1-interacting ankyrin-related ADP-ribose polymerase 2(gene name synonym)|uniprotkb:Tankyrase II(gene name synonym)|uniprotkb:Tankyrase-like protein(gene name synonym)|uniprotkb:Tankyrase-related protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 6(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase-2(gene name synonym)|uniprotkb:Tankyrase-2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653938|imex:IM-16425-124	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_079511.1|dip:DIP-42098N|rcsb pdb:3P0Q|rcsb pdb:3TWQ|rcsb pdb:3TWR|rcsb pdb:3TWS|rcsb pdb:3TWT|rcsb pdb:3TWU|rcsb pdb:3TWV|rcsb pdb:3TWW|rcsb pdb:3TWX|rcsb pdb:3U9H|rcsb pdb:3U9Y|rcsb pdb:3UA9|rcsb pdb:3W51|rcsb pdb:4AVU|rcsb pdb:4AVW|rcsb pdb:4BFP|rcsb pdb:4BJ9|rcsb pdb:4BJB|rcsb pdb:4BJC|rcsb pdb:4BS4|rcsb pdb:4BU3|rcsb pdb:4BU5|rcsb pdb:4BU6|rcsb pdb:4BU7|rcsb pdb:4BU8|rcsb pdb:4BU9|rcsb pdb:4BUA|rcsb pdb:4BUD|rcsb pdb:4BUE|rcsb pdb:4BUF|rcsb pdb:4BUI|rcsb pdb:4BUS|rcsb pdb:4BUT|rcsb pdb:4BUU|rcsb pdb:4BUV|rcsb pdb:4BUW|rcsb pdb:4BUX|rcsb pdb:4BUY|rcsb pdb:4HKI|rcsb pdb:4HKK|rcsb pdb:4HKN|ensembl:ENSG00000107854(gene)|ensembl:ENST00000371627(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|mint:Q9H2K2|rcsb pdb:2Y0I|rcsb pdb:3KR7|rcsb pdb:3KR8|rcsb pdb:3MHJ|rcsb pdb:3MHK|rcsb pdb:3P0N|rcsb pdb:3P0P|rcsb pdb:6TKP|rcsb pdb:6TKQ|rcsb pdb:6TKR|rcsb pdb:6TKS|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-5545619|reactome:R-HSA-5689880|reactome:R-HSA-8948751|rcsb pdb:6TKN|rcsb pdb:4HL5|rcsb pdb:4HLF|rcsb pdb:4HLG|rcsb pdb:4HLH|rcsb pdb:4HLK|rcsb pdb:4HLM|rcsb pdb:4HMH|rcsb pdb:4HYF|rcsb pdb:4IUE|rcsb pdb:4J1Z|rcsb pdb:4J21|rcsb pdb:4J22|rcsb pdb:4J3L|rcsb pdb:4J3M|rcsb pdb:4KZL|rcsb pdb:4KZQ|rcsb pdb:4KZU|rcsb pdb:4L09|rcsb pdb:4L0B|rcsb pdb:4L0I|rcsb pdb:4L0T|rcsb pdb:4L0V|rcsb pdb:4L10|rcsb pdb:4L2F|rcsb pdb:4L2G|rcsb pdb:4L2K|rcsb pdb:4L31|rcsb pdb:4L32|rcsb pdb:4L33|rcsb pdb:4L34|rcsb pdb:4M7B|rcsb pdb:4PML|rcsb pdb:4PNL|rcsb pdb:4PNM|rcsb pdb:4PNN|rcsb pdb:4PNQ|rcsb pdb:4PNR|rcsb pdb:4PNS|rcsb pdb:4PNT|rcsb pdb:4TJU|rcsb pdb:4TJW|rcsb pdb:4TJY|rcsb pdb:4TK0|rcsb pdb:4TK5|rcsb pdb:4TKF|rcsb pdb:4TKG|rcsb pdb:4TKI|rcsb pdb:4UFU|rcsb pdb:4UFY|rcsb pdb:4UHG|rcsb pdb:4UI3|rcsb pdb:4UI4|rcsb pdb:4UI5|rcsb pdb:4UI6|rcsb pdb:4UI7|rcsb pdb:4UI8|rcsb pdb:4UVL|rcsb pdb:4UVN|rcsb pdb:4UVO|rcsb pdb:4UVP|rcsb pdb:4UVS|rcsb pdb:4UVT|rcsb pdb:4UVU|rcsb pdb:4UVV|rcsb pdb:4UVW|rcsb pdb:4UVX|rcsb pdb:4UVY|rcsb pdb:4UVZ|rcsb pdb:4UX4|rcsb pdb:4W5I|rcsb pdb:4Z68|rcsb pdb:5ADQ|rcsb pdb:5ADR|rcsb pdb:5ADS|rcsb pdb:5ADT|rcsb pdb:5AEH|rcsb pdb:5AKU|rcsb pdb:5AKW|rcsb pdb:5AL1|rcsb pdb:5AL2|rcsb pdb:5AL3|rcsb pdb:5AL4|rcsb pdb:5AL5|rcsb pdb:5BXO|rcsb pdb:5BXU|rcsb pdb:5C5P|rcsb pdb:4L0S|rcsb pdb:5C5Q|rcsb pdb:5C5R|rcsb pdb:5DCZ|rcsb pdb:5FPF|rcsb pdb:5FPG|rcsb pdb:5JRT|rcsb pdb:5NOB|rcsb pdb:5NSP|rcsb pdb:5NUT|rcsb pdb:5OWS|rcsb pdb:5OWT|rcsb pdb:6TG4|rcsb pdb:6TKM|genbank_protein_gi:21361945(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:pf0mQR/in4ShtYc1xmCF042/v/A9606	intact-crc:A6054CA6D816EE37|rigid:KxozzwQ8SPh4A6jaTu1pjmtrfKA	false	sufficient binding region:42-693	sufficient binding region:716-1166	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H2K2	uniprotkb:O15084	intact:EBI-4398527|uniprotkb:Q9H8F2|uniprotkb:Q9HAS4|uniprotkb:B2RBD3|ensembl:ENSP00000360689	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:tnks2_human(display_long)|uniprotkb:TNKS2(gene name)|psi-mi:TNKS2(display_short)|uniprotkb:PARP5B(gene name synonym)|uniprotkb:TANK2(gene name synonym)|uniprotkb:TNKL(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 5B(gene name synonym)|uniprotkb:TNKS-2(gene name synonym)|uniprotkb:TRF1-interacting ankyrin-related ADP-ribose polymerase 2(gene name synonym)|uniprotkb:Tankyrase II(gene name synonym)|uniprotkb:Tankyrase-like protein(gene name synonym)|uniprotkb:Tankyrase-related protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 6(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase-2(gene name synonym)|uniprotkb:Tankyrase-2(gene name synonym)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653921|imex:IM-16425-123	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079511.1|dip:DIP-42098N|rcsb pdb:3P0Q|rcsb pdb:3TWQ|rcsb pdb:3TWR|rcsb pdb:3TWS|rcsb pdb:3TWT|rcsb pdb:3TWU|rcsb pdb:3TWV|rcsb pdb:3TWW|rcsb pdb:3TWX|rcsb pdb:3U9H|rcsb pdb:3U9Y|rcsb pdb:3UA9|rcsb pdb:3W51|rcsb pdb:4AVU|rcsb pdb:4AVW|rcsb pdb:4BFP|rcsb pdb:4BJ9|rcsb pdb:4BJB|rcsb pdb:4BJC|rcsb pdb:4BS4|rcsb pdb:4BU3|rcsb pdb:4BU5|rcsb pdb:4BU6|rcsb pdb:4BU7|rcsb pdb:4BU8|rcsb pdb:4BU9|rcsb pdb:4BUA|rcsb pdb:4BUD|rcsb pdb:4BUE|rcsb pdb:4BUF|rcsb pdb:4BUI|rcsb pdb:4BUS|rcsb pdb:4BUT|rcsb pdb:4BUU|rcsb pdb:4BUV|rcsb pdb:4BUW|rcsb pdb:4BUX|rcsb pdb:4BUY|rcsb pdb:4HKI|rcsb pdb:4HKK|rcsb pdb:4HKN|ensembl:ENSG00000107854(gene)|ensembl:ENST00000371627(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|mint:Q9H2K2|rcsb pdb:2Y0I|rcsb pdb:3KR7|rcsb pdb:3KR8|rcsb pdb:3MHJ|rcsb pdb:3MHK|rcsb pdb:3P0N|rcsb pdb:3P0P|rcsb pdb:6TKP|rcsb pdb:6TKQ|rcsb pdb:6TKR|rcsb pdb:6TKS|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-5545619|reactome:R-HSA-5689880|reactome:R-HSA-8948751|rcsb pdb:6TKN|rcsb pdb:4HL5|rcsb pdb:4HLF|rcsb pdb:4HLG|rcsb pdb:4HLH|rcsb pdb:4HLK|rcsb pdb:4HLM|rcsb pdb:4HMH|rcsb pdb:4HYF|rcsb pdb:4IUE|rcsb pdb:4J1Z|rcsb pdb:4J21|rcsb pdb:4J22|rcsb pdb:4J3L|rcsb pdb:4J3M|rcsb pdb:4KZL|rcsb pdb:4KZQ|rcsb pdb:4KZU|rcsb pdb:4L09|rcsb pdb:4L0B|rcsb pdb:4L0I|rcsb pdb:4L0T|rcsb pdb:4L0V|rcsb pdb:4L10|rcsb pdb:4L2F|rcsb pdb:4L2G|rcsb pdb:4L2K|rcsb pdb:4L31|rcsb pdb:4L32|rcsb pdb:4L33|rcsb pdb:4L34|rcsb pdb:4M7B|rcsb pdb:4PML|rcsb pdb:4PNL|rcsb pdb:4PNM|rcsb pdb:4PNN|rcsb pdb:4PNQ|rcsb pdb:4PNR|rcsb pdb:4PNS|rcsb pdb:4PNT|rcsb pdb:4TJU|rcsb pdb:4TJW|rcsb pdb:4TJY|rcsb pdb:4TK0|rcsb pdb:4TK5|rcsb pdb:4TKF|rcsb pdb:4TKG|rcsb pdb:4TKI|rcsb pdb:4UFU|rcsb pdb:4UFY|rcsb pdb:4UHG|rcsb pdb:4UI3|rcsb pdb:4UI4|rcsb pdb:4UI5|rcsb pdb:4UI6|rcsb pdb:4UI7|rcsb pdb:4UI8|rcsb pdb:4UVL|rcsb pdb:4UVN|rcsb pdb:4UVO|rcsb pdb:4UVP|rcsb pdb:4UVS|rcsb pdb:4UVT|rcsb pdb:4UVU|rcsb pdb:4UVV|rcsb pdb:4UVW|rcsb pdb:4UVX|rcsb pdb:4UVY|rcsb pdb:4UVZ|rcsb pdb:4UX4|rcsb pdb:4W5I|rcsb pdb:4Z68|rcsb pdb:5ADQ|rcsb pdb:5ADR|rcsb pdb:5ADS|rcsb pdb:5ADT|rcsb pdb:5AEH|rcsb pdb:5AKU|rcsb pdb:5AKW|rcsb pdb:5AL1|rcsb pdb:5AL2|rcsb pdb:5AL3|rcsb pdb:5AL4|rcsb pdb:5AL5|rcsb pdb:5BXO|rcsb pdb:5BXU|rcsb pdb:5C5P|rcsb pdb:4L0S|rcsb pdb:5C5Q|rcsb pdb:5C5R|rcsb pdb:5DCZ|rcsb pdb:5FPF|rcsb pdb:5FPG|rcsb pdb:5JRT|rcsb pdb:5NOB|rcsb pdb:5NSP|rcsb pdb:5NUT|rcsb pdb:5OWS|rcsb pdb:5OWT|rcsb pdb:6TG4|rcsb pdb:6TKM|genbank_protein_gi:21361945(identity)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:pf0mQR/in4ShtYc1xmCF042/v/A9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	intact-crc:072F68D3523FBE81|rigid:KxozzwQ8SPh4A6jaTu1pjmtrfKA	false	sufficient binding region:506-1166	sufficient binding region:42-693	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:Q9H2K2	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-4398527|uniprotkb:Q9H8F2|uniprotkb:Q9HAS4|uniprotkb:B2RBD3|ensembl:ENSP00000360689	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:tnks2_human(display_long)|uniprotkb:TNKS2(gene name)|psi-mi:TNKS2(display_short)|uniprotkb:PARP5B(gene name synonym)|uniprotkb:TANK2(gene name synonym)|uniprotkb:TNKL(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 5B(gene name synonym)|uniprotkb:TNKS-2(gene name synonym)|uniprotkb:TRF1-interacting ankyrin-related ADP-ribose polymerase 2(gene name synonym)|uniprotkb:Tankyrase II(gene name synonym)|uniprotkb:Tankyrase-like protein(gene name synonym)|uniprotkb:Tankyrase-related protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 6(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase-2(gene name synonym)|uniprotkb:Tankyrase-2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653904|imex:IM-16425-122	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_079511.1|dip:DIP-42098N|rcsb pdb:3P0Q|rcsb pdb:3TWQ|rcsb pdb:3TWR|rcsb pdb:3TWS|rcsb pdb:3TWT|rcsb pdb:3TWU|rcsb pdb:3TWV|rcsb pdb:3TWW|rcsb pdb:3TWX|rcsb pdb:3U9H|rcsb pdb:3U9Y|rcsb pdb:3UA9|rcsb pdb:3W51|rcsb pdb:4AVU|rcsb pdb:4AVW|rcsb pdb:4BFP|rcsb pdb:4BJ9|rcsb pdb:4BJB|rcsb pdb:4BJC|rcsb pdb:4BS4|rcsb pdb:4BU3|rcsb pdb:4BU5|rcsb pdb:4BU6|rcsb pdb:4BU7|rcsb pdb:4BU8|rcsb pdb:4BU9|rcsb pdb:4BUA|rcsb pdb:4BUD|rcsb pdb:4BUE|rcsb pdb:4BUF|rcsb pdb:4BUI|rcsb pdb:4BUS|rcsb pdb:4BUT|rcsb pdb:4BUU|rcsb pdb:4BUV|rcsb pdb:4BUW|rcsb pdb:4BUX|rcsb pdb:4BUY|rcsb pdb:4HKI|rcsb pdb:4HKK|rcsb pdb:4HKN|ensembl:ENSG00000107854(gene)|ensembl:ENST00000371627(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|mint:Q9H2K2|rcsb pdb:2Y0I|rcsb pdb:3KR7|rcsb pdb:3KR8|rcsb pdb:3MHJ|rcsb pdb:3MHK|rcsb pdb:3P0N|rcsb pdb:3P0P|rcsb pdb:6TKP|rcsb pdb:6TKQ|rcsb pdb:6TKR|rcsb pdb:6TKS|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-5545619|reactome:R-HSA-5689880|reactome:R-HSA-8948751|rcsb pdb:6TKN|rcsb pdb:4HL5|rcsb pdb:4HLF|rcsb pdb:4HLG|rcsb pdb:4HLH|rcsb pdb:4HLK|rcsb pdb:4HLM|rcsb pdb:4HMH|rcsb pdb:4HYF|rcsb pdb:4IUE|rcsb pdb:4J1Z|rcsb pdb:4J21|rcsb pdb:4J22|rcsb pdb:4J3L|rcsb pdb:4J3M|rcsb pdb:4KZL|rcsb pdb:4KZQ|rcsb pdb:4KZU|rcsb pdb:4L09|rcsb pdb:4L0B|rcsb pdb:4L0I|rcsb pdb:4L0T|rcsb pdb:4L0V|rcsb pdb:4L10|rcsb pdb:4L2F|rcsb pdb:4L2G|rcsb pdb:4L2K|rcsb pdb:4L31|rcsb pdb:4L32|rcsb pdb:4L33|rcsb pdb:4L34|rcsb pdb:4M7B|rcsb pdb:4PML|rcsb pdb:4PNL|rcsb pdb:4PNM|rcsb pdb:4PNN|rcsb pdb:4PNQ|rcsb pdb:4PNR|rcsb pdb:4PNS|rcsb pdb:4PNT|rcsb pdb:4TJU|rcsb pdb:4TJW|rcsb pdb:4TJY|rcsb pdb:4TK0|rcsb pdb:4TK5|rcsb pdb:4TKF|rcsb pdb:4TKG|rcsb pdb:4TKI|rcsb pdb:4UFU|rcsb pdb:4UFY|rcsb pdb:4UHG|rcsb pdb:4UI3|rcsb pdb:4UI4|rcsb pdb:4UI5|rcsb pdb:4UI6|rcsb pdb:4UI7|rcsb pdb:4UI8|rcsb pdb:4UVL|rcsb pdb:4UVN|rcsb pdb:4UVO|rcsb pdb:4UVP|rcsb pdb:4UVS|rcsb pdb:4UVT|rcsb pdb:4UVU|rcsb pdb:4UVV|rcsb pdb:4UVW|rcsb pdb:4UVX|rcsb pdb:4UVY|rcsb pdb:4UVZ|rcsb pdb:4UX4|rcsb pdb:4W5I|rcsb pdb:4Z68|rcsb pdb:5ADQ|rcsb pdb:5ADR|rcsb pdb:5ADS|rcsb pdb:5ADT|rcsb pdb:5AEH|rcsb pdb:5AKU|rcsb pdb:5AKW|rcsb pdb:5AL1|rcsb pdb:5AL2|rcsb pdb:5AL3|rcsb pdb:5AL4|rcsb pdb:5AL5|rcsb pdb:5BXO|rcsb pdb:5BXU|rcsb pdb:5C5P|rcsb pdb:4L0S|rcsb pdb:5C5Q|rcsb pdb:5C5R|rcsb pdb:5DCZ|rcsb pdb:5FPF|rcsb pdb:5FPG|rcsb pdb:5JRT|rcsb pdb:5NOB|rcsb pdb:5NSP|rcsb pdb:5NUT|rcsb pdb:5OWS|rcsb pdb:5OWT|rcsb pdb:6TG4|rcsb pdb:6TKM|genbank_protein_gi:21361945(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:pf0mQR/in4ShtYc1xmCF042/v/A9606	intact-crc:90D42B22FE1FE99B|rigid:KxozzwQ8SPh4A6jaTu1pjmtrfKA	false	sufficient binding region:42-693	sufficient binding region:252-1166	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35573	uniprotkb:Q9UKG1	intact:EBI-465104|uniprotkb:P78354|uniprotkb:P78544|uniprotkb:Q6AZ90|ensembl:ENSP00000294724|ensembl:ENSP00000355106|ensembl:ENSP00000359182|ensembl:ENSP00000359184|uniprotkb:Q9UF08|uniprotkb:A6NCX7|uniprotkb:A6NEK2|uniprotkb:Q59H92|uniprotkb:D3DT51	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:gde_human(display_long)|uniprotkb:AGL(gene name)|psi-mi:AGL(display_short)|uniprotkb:GDE(gene name synonym)|uniprotkb:Glycogen debrancher(gene name synonym)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654007|imex:IM-16425-128	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-70221|ensembl:ENSG00000162688(gene)|ensembl:ENST00000294724(transcript)|ensembl:ENST00000361915(transcript)|ensembl:ENST00000370163(transcript)|ensembl:ENST00000370165(transcript)|go:"GO:0004133"(glycogen debranching enzyme activity)|go:"GO:0004134"(4-alpha-glucanotransferase activity)|go:"GO:0004135"(amylo-alpha-1,6-glucosidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0016234"(inclusion body)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043033"(isoamylase complex)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0102500"(beta-maltose 4-alpha-glucanotransferase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006421(Glycogen debranching enzyme)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010401(Amylo-alpha-1,6-glucosidase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR029436|interpro:IPR032788|interpro:IPR032790|interpro:IPR032792|reactome:R-HSA-6798695|go:"GO:0005978"(glycogen biosynthetic process)|refseq:NP_000019.2|refseq:NP_000633.2|refseq:NP_000634.2|refseq:NP_000635.2|refseq:NP_000637.2|refseq:XP_005270614.1|genbank_protein_gi:116734859(identity)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:HVacsWpe2mbhHq9aKVlwf60H2lg9606	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:74BE20C6A68500C3|rigid:Dl5LlyeDS349Ryp+5hUJ9kcTSuE	false	sufficient binding region:1496-1532..1532	sufficient binding region:1-709	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:P35609	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653989|imex:IM-16425-127	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	intact-crc:D6B3C95BEED0F5CF|rigid:A/vnC8xrA7X2lG3e4ePpF7bL+MY	false	sufficient binding region:1-709	sufficient binding region:431-894(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15084	uniprotkb:Q9BZF9	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	intact:EBI-350510|uniprotkb:Q14DD3|uniprotkb:Q8N3B8|uniprotkb:Q9HCL1|uniprotkb:Q9NWC6|uniprotkb:G3XAG2|uniprotkb:Q96NH6|intact:EBI-10977773|ensembl:ENSP00000314556	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:uaca_human(display_long)|uniprotkb:UACA(gene name)|psi-mi:UACA(display_short)|uniprotkb:KIAA1561(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5653972|imex:IM-16425-126	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005|genbank_protein_gi:46195712(identity)	refseq:NP_001008225.1|refseq:NP_060473.2|dip:DIP-33117N|ensembl:ENSG00000137831(gene)|ensembl:ENST00000322954(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030227|interpro:IPR036770|mint:Q9BZF9|reactome:R-HSA-9013407|reactome:R-HSA-9627069|genbank_protein_gi:59850761(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rogid:F58VkGk2DBsUUrB+wgknUFZhJ+E9606	intact-crc:88510D2DDC56ADB0|rigid:oZvrNztO0tNH7GiKs9NflEo7DnE	false	sufficient binding region:42-693	sufficient binding region:153-1416	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15327	uniprotkb:Q9UKG1	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654024|imex:IM-16425-129	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:1F8E3E318B0480AE|rigid:6z3fK99CUf5I0LInQxJiJMIFJMU	false	sufficient binding region:74-319	sufficient binding region:1-709	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:O14983	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-359186|uniprotkb:O14984|uniprotkb:A8K5J9|ensembl:ENSP00000349595|uniprotkb:B3KY17	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:at2a1_human(display_long)|uniprotkb:ATP2A1(gene name)|psi-mi:ATP2A1(display_short)|uniprotkb:Calcium pump 1(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654058|imex:IM-16425-131	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	refseq:NP_004311.1|refseq:NP_775293.1|ensembl:ENSG00000196296(gene)|ensembl:ENST00000357084(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0031673"(H zone)|go:"GO:0031674"(I band)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034704"(calcium channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:0106134"(positive regulation of cardiac muscle cell contraction)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902082"(positive regulation of calcium ion import into sarcoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O14983|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001273004.1|genbank_protein_gi:47132613(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:3cHH/E8HuaFCoTd7hO/0SFTnqtg9606	intact-crc:BE6CF72C99782E13|rigid:3aznOiYcjEs5/1VnW4OJEii5tmo	false	sufficient binding region:1-709	sufficient binding region:431-1001(IPR005782)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:Q8NEU8	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-741261|ensembl:ENSP00000258530|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654041|imex:IM-16425-130	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|ensembl:ENSG00000136044(gene)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000258530(transcript)|go:"GO:0044354"(macropinosome)|go:"GO:0001726"(ruffle)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|refseq:NP_060641.2|refseq:XP_016875042.1|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1|genbank_protein_gi:82617617(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	intact-crc:F66BF98D1E967F9C|rigid:3VkvU2LTbdk9sGp9hkPVdiLSZR4	false	sufficient binding region:1-709	sufficient binding region:1-664	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:Q8WZ74	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654095|imex:IM-16425-133	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770|genbank_protein_gi:92091570(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606	intact-crc:B03590BF095B14D3|rigid:iYOJLXtmXGJZ9zyzV78VtofSxsY	false	sufficient binding region:1-709	sufficient binding region:253-1663..1663	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:O00499	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654076|imex:IM-16425-132	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N|genbank_protein_gi:4757748(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606	intact-crc:6413D19545215557|rigid:j70soNzLPA6fzdytVJUsJt1q2jI	false	sufficient binding region:1-709	sufficient binding region:154-593(IPR003005)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NYF0	uniprotkb:Q9UKG1	intact:EBI-3951744|uniprotkb:Q86TY0|ensembl:ENSP00000337439|uniprotkb:A8MYJ2	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:dact1_human(display_long)|uniprotkb:DACT1(gene name)|psi-mi:DACT1(display_short)|uniprotkb:DPR1(gene name synonym)|uniprotkb:HNG3(gene name synonym)|uniprotkb:Hepatocellular carcinoma novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654112|imex:IM-16425-134	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165617(gene)|ensembl:ENST00000335867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-HSA-4641258|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|refseq:NP_057735.2|refseq:NP_001072988.1|refseq:XP_006720230.1|genbank_protein_gi:118498369(identity)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:4LFgplvhFtCWUI/6Pux6Z23NNVY9606	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:E0163E6FF462417B|rigid:XcX5CkW0ms644XJZBNpiMkEsTRg	false	sufficient binding region:48-836	sufficient binding region:1-709	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:Q03001	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654146|imex:IM-16425-136	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:20357503(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	intact-crc:68CC2FB6C6B23476|rigid:YSAscY+3OZ3GAYU/rvYhQm2QGSU	false	sufficient binding region:1-709	sufficient binding region:1234-7570(IPR001101)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03001	uniprotkb:Q9UKG1	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654164|imex:IM-16425-137	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:86AC578ECB11CE62|rigid:YSAscY+3OZ3GAYU/rvYhQm2QGSU	false	sufficient binding region:985-7570	sufficient binding region:1-709	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:P50570	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654129|imex:IM-16425-135	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|genbank_protein_gi:56549124(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	intact-crc:DA4E55133CF72090|rigid:L1/ABrgFDf6pD6Q100/yHOt1ThY	false	sufficient binding region:1-709	sufficient binding region:513-870	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:P51654	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-5654198|uniprotkb:C9JLE3|uniprotkb:Q2L880|uniprotkb:G3V1R0|uniprotkb:Q2L882|ensembl:ENSP00000359854	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:gpc3_human(display_long)|uniprotkb:GTR2-2(gene name synonym)|uniprotkb:Intestinal protein OCI-5(gene name synonym)|uniprotkb:MXR7(gene name synonym)|uniprotkb:OCI5(gene name synonym)|uniprotkb:GPC3(gene name)|psi-mi:GPC3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654202|imex:IM-16425-139	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	refseq:NP_001158091.1|dip:DIP-61509N|refseq:NP_004475.1|refseq:NP_001158089.1|ensembl:ENSG00000147257(gene)|ensembl:ENST00000370818(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009617"(response to bacterium)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0016477"(cell migration)|go:"GO:0030282"(bone mineralization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060422"(peptidyl-dipeptidase inhibitor activity)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072111"(cell proliferation involved in kidney development)|go:"GO:0072138"(mesenchymal cell proliferation involved in ureteric bud development)|go:"GO:0072180"(mesonephric duct morphogenesis)|go:"GO:0072203"(cell proliferation involved in metanephros development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1905475"(regulation of protein localization to membrane)|go:"GO:2000050"(regulation of non-canonical Wnt signaling pathway)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR001863(Glypican)|interpro:IPR015501(Glypican 3)|interpro:IPR019803|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-381426|reactome:R-HSA-4420332|reactome:R-HSA-8957275|reactome:R-HSA-975634|genbank_protein_gi:5360213(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:+H2PtA0Y61S+2l56UPxwxBpCosc9606	intact-crc:F32D838404E0B3B0|rigid:iw2vao7Vk1r8rmdMRi8ZY2A6zk4	false	sufficient binding region:1-709	sufficient binding region:381-580(IPR001863)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:Q9Y4J8	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654181|imex:IM-16425-138	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1|genbank_protein_gi:42717996(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606	intact-crc:722D7D7E3C3354AF|rigid:5XOtOUjKdytkSeRWQt/g0S18cyI	false	sufficient binding region:1-709	sufficient binding region:468-743	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C6	uniprotkb:Q9UKG1	intact:EBI-5654244|uniprotkb:Q8NDZ1|uniprotkb:Q8N389|uniprotkb:B2RCI1|ensembl:ENSP00000355319	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:cipc_human(display_long)|uniprotkb:CIPC(gene name)|psi-mi:CIPC(display_short)|uniprotkb:CLOCK-interacting circadian protein(gene name synonym)|uniprotkb:KIAA1737(gene name synonym)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654239|imex:IM-16425-141	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_219494.2|ensembl:ENSP00000355319|ensembl:ENSG00000198894(gene)|ensembl:ENST00000361786(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR031602|genbank_protein_gi:32307174(identity)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ydeyuH6UDpjAXnd5dpaHdJnwooQ9606	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:A4841C1A81A3BEA6|rigid:jV6Vuy0++8nx0DRc2aVXmxPWquY	false	sufficient binding region:269-399	sufficient binding region:1-709	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:Q9NQ29	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-473747|uniprotkb:Q96S32|uniprotkb:Q9NPH4|uniprotkb:B8ZZ13|ensembl:ENSP00000293872	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:luc7l_human(display_long)|uniprotkb:SR+89(gene name synonym)|uniprotkb:Putative SR protein LUC7B1(gene name synonym)|uniprotkb:LUC7L(gene name)|psi-mi:LUC7L(display_short)|uniprotkb:LUC7L1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654263|imex:IM-16425-142	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	refseq:NP_001307155.1|refseq:NP_001317349.1|refseq:NP_060502.1|refseq:NP_958815.1|ensembl:ENSG00000007392(gene)|ensembl:ENST00000293872(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0042802"(identical protein binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9NQ29|genbank_protein_gi:41393553(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:Hsl0VZTCTP6UrKlo/FHOVwZqCaw9606	intact-crc:ED64180EA5ABE32A|rigid:y7YWho2u9D7WA1spgKXT8uDx3qQ	false	sufficient binding region:1-709	sufficient binding region:103-371(IPR004882)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:P04792	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654220|imex:IM-16425-140	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N|genbank_protein_gi:15126734(identity)	-	-	crc64:1B4DC44A6F6606D5	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606	intact-crc:22EE3DE392889008|rigid:Itk17bv09+XaK1sAdpEO/bx60O8	false	sufficient binding region:1-709	sufficient binding region:157-205..205(IPR002068)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75592	uniprotkb:Q9UKG1	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654281|imex:IM-16425-143	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055872.4|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003646(Bacterial SH3-like region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|ensembl:ENSG00000005810(gene)|ensembl:ENST00000544440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|dip:DIP-28142N|genbank_protein_gi:126116564(identity)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/07/05	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:834615B5F0C2045E|rigid:l8NLxi2sO6g8JZE+yBTaX+zW084	false	sufficient binding region:3152-4678	sufficient binding region:1-709	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11055	uniprotkb:Q9UKG1	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654304|imex:IM-16425-144	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:EB547F94298BFE33|rigid:10DLRCVRsokUudLUD7SE+Hm5Spk	false	sufficient binding region:1138-1940	sufficient binding region:1-709	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:Q8N0X7	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-2643803|uniprotkb:Q9H1T3|uniprotkb:Q9H1T2|uniprotkb:O60349|uniprotkb:Q86Y67|ensembl:ENSP00000347314|ensembl:ENSP00000406061|ensembl:ENSP00000414147|ensembl:ENSP00000473599|ensembl:ENSP00000497209	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:spart_human(display_long)|uniprotkb:SPART(gene name)|psi-mi:SPART(display_short)|uniprotkb:KIAA0610(gene name synonym)|uniprotkb:SPG20(gene name synonym)|uniprotkb:Spastic paraplegia 20 protein(gene name synonym)|uniprotkb:TAHCCP1(gene name synonym)|uniprotkb:Trans-activated by hepatitis C virus core protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654321|imex:IM-16425-145	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	refseq:NP_001135766.1|refseq:NP_001135767.1|refseq:NP_001135768.1|refseq:NP_055902.1|refseq:XP_011533314.1|refseq:XP_005266370.1|refseq:XP_005266371.1|refseq:XP_005266372.1|ensembl:ENSG00000133104(gene)|ensembl:ENST00000355182(transcript)|ensembl:ENST00000438666(transcript)|ensembl:ENST00000451493(transcript)|ensembl:ENST00000494062(transcript)|ensembl:ENST00000650221(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009838"(abscission)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0048698"(negative regulation of collateral sprouting in absence of injury)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051301"(cell division)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060612"(adipose tissue development)|interpro:IPR007330(MIT)|interpro:IPR009686(Senescence-associated)|interpro:IPR036181|rcsb pdb:2DL1|rcsb pdb:4U7I|go:"GO:0030514"(negative regulation of BMP signaling pathway)|refseq:XP_005266374.1|genbank_protein_gi:40806197(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:Km2bYRg7JLYy7voEgYVdAHZhzE09606	intact-crc:ED273D3A7B1CE2BB|rigid:Tf57BR2bnuto+ukGJHR4G4ujKsM	false	sufficient binding region:1-709	sufficient binding region:27-666	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBL3	uniprotkb:P68032	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654374|imex:IM-16425-148	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026|genbank_protein_gi:46411161(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606	intact-crc:06972094345D4237|rigid:t+1XMDTB9UdYbEVTIJzW7BwB+SM	false	sufficient binding region:1-628	sufficient binding region:151-377	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:Q8WXH0	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-2372294|uniprotkb:Q540G1|uniprotkb:Q8N1S3|uniprotkb:Q8NF49|uniprotkb:Q8TER7|uniprotkb:Q8WWW3|uniprotkb:Q8WWW4|uniprotkb:Q8WWW5|uniprotkb:Q8WXH1|uniprotkb:Q9NU50|uniprotkb:Q9UFQ4|uniprotkb:Q9Y2L4|uniprotkb:Q9Y4R1|uniprotkb:Q86YP9|uniprotkb:B4DND7|uniprotkb:B4DPR6|uniprotkb:I6XXQ5|ensembl:ENSP00000341781	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:syne2_human(display_long)|uniprotkb:SYNE2(gene name)|psi-mi:SYNE2(display_short)|uniprotkb:KIAA1011(gene name synonym)|uniprotkb:NUA(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 2(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 2(gene name synonym)|uniprotkb:Nucleus and actin connecting element protein(gene name synonym)|uniprotkb:KASH domain-containing protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654338|imex:IM-16425-146	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	ensembl:ENSP00000344528|ensembl:ENSP00000341781|ensembl:ENST00000358025|ensembl:ENSP00000350719|ensembl:ENST00000458046|ensembl:ENSP00000391937|ensembl:ENST00000555002|ensembl:ENSP00000450831|ensembl:ENST00000341472|refseq:NP_055995.4|refseq:NP_878914.1|refseq:NP_878917.1|refseq:NP_878918.2|dip:DIP-53409N|ensembl:ENSG00000054654(gene)|ensembl:ENST00000344113(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005925"(focal adhesion)|go:"GO:0007097"(nuclear migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR030266|interpro:IPR036872|rcsb pdb:4DXS|rcsb pdb:4FI9|rcsb pdb:6XF1|reactome:R-HSA-1221632|genbank_protein_gi:118918406(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:wLHWOXR+dUHkcs93g+F2av/9wm49606	intact-crc:D849213BEA8F1867|rigid:nIOzHWyhiY4677OqvnGDJjIl/Xo	false	sufficient binding region:1-709	sufficient binding region:5768-6885(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:Q8WXH0	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-2372294|uniprotkb:Q540G1|uniprotkb:Q8N1S3|uniprotkb:Q8NF49|uniprotkb:Q8TER7|uniprotkb:Q8WWW3|uniprotkb:Q8WWW4|uniprotkb:Q8WWW5|uniprotkb:Q8WXH1|uniprotkb:Q9NU50|uniprotkb:Q9UFQ4|uniprotkb:Q9Y2L4|uniprotkb:Q9Y4R1|uniprotkb:Q86YP9|uniprotkb:B4DND7|uniprotkb:B4DPR6|uniprotkb:I6XXQ5|ensembl:ENSP00000341781	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:syne2_human(display_long)|uniprotkb:SYNE2(gene name)|psi-mi:SYNE2(display_short)|uniprotkb:KIAA1011(gene name synonym)|uniprotkb:NUA(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 2(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 2(gene name synonym)|uniprotkb:Nucleus and actin connecting element protein(gene name synonym)|uniprotkb:KASH domain-containing protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654356|imex:IM-16425-147	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	ensembl:ENSP00000344528|ensembl:ENSP00000341781|ensembl:ENST00000358025|ensembl:ENSP00000350719|ensembl:ENST00000458046|ensembl:ENSP00000391937|ensembl:ENST00000555002|ensembl:ENSP00000450831|ensembl:ENST00000341472|refseq:NP_055995.4|refseq:NP_878914.1|refseq:NP_878917.1|refseq:NP_878918.2|dip:DIP-53409N|ensembl:ENSG00000054654(gene)|ensembl:ENST00000344113(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005925"(focal adhesion)|go:"GO:0007097"(nuclear migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR030266|interpro:IPR036872|rcsb pdb:4DXS|rcsb pdb:4FI9|rcsb pdb:6XF1|reactome:R-HSA-1221632|genbank_protein_gi:118918406(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:wLHWOXR+dUHkcs93g+F2av/9wm49606	intact-crc:1F9215E8C45ACB38|rigid:nIOzHWyhiY4677OqvnGDJjIl/Xo	false	sufficient binding region:1-709	sufficient binding region:5939-6885(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBL3	uniprotkb:Q7L5N1	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	intact:EBI-486838|uniprotkb:O15387|uniprotkb:A4D2A3|ensembl:ENSP00000304102	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:csn6_human(display_long)|uniprotkb:COPS6(gene name)|psi-mi:COPS6(display_short)|uniprotkb:CSN6(gene name synonym)|uniprotkb:HVIP(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 6(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym)|uniprotkb:MOV34 homolog(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654425|imex:IM-16425-151	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	refseq:NP_006824.2|ensembl:ENSG00000168090(gene)|ensembl:ENST00000303904(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR033859|interpro:IPR024969|interpro:IPR037518|mint:Q7L5N1|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4QFT|rcsb pdb:4R14|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|dip:DIP-32655N|genbank_protein_gi:38027945(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	rogid:hyuYyAujJCJtbfS2tJ+UgH7jWP89606	intact-crc:62439E5ADFAA77AC|rigid:4uhmTaLP+hP6+mnt7DtJejOdJmA	false	sufficient binding region:1-628	sufficient binding region:6-327(IPR000555)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15327	uniprotkb:Q9UBL3	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654408|imex:IM-16425-150	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	intact-crc:585204E5D753FD37|rigid:AQA8NF6+xuT8RG+LxlQwvPvgL7g	false	sufficient binding region:73-319	sufficient binding region:1-628	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35609	uniprotkb:Q9UBL3	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654391|imex:IM-16425-149	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	intact-crc:6CAF3D3FBF072378|rigid:XxFsFKAB2pMUfnur09Ndpmq1Pps	false	sufficient binding region:1-894	sufficient binding region:1-628	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBL3	uniprotkb:Q9C005	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654443|imex:IM-16425-152	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N|genbank_protein_gi:59710088(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606	intact-crc:BBF34B03740780D0|rigid:aJDQjhaDClfi1udEmAkA8wQ24v4	false	sufficient binding region:1-628	sufficient binding region:15-99..99(IPR007858)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBL3	uniprotkb:Q00872	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654478|imex:IM-16425-154	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:62D798EE9160D4CF|rigid:ZUqJ6wctmbcF6EgHbF7qA4YCkwA	false	sufficient binding region:1-628	sufficient binding region:603-1141(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHC7	uniprotkb:Q9UBL3	intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym)	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654461|imex:IM-16425-153	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011514299.1|refseq:XP_011514300.1|refseq:NP_001138597.1|refseq:NP_038474.2|ensembl:ENSP00000255977|ensembl:ENST00000443720|ensembl:ENSP00000416369|ensembl:ENST00000474576|ensembl:ENSP00000417863|ensembl:ENSG00000133606(gene)|ensembl:ENST00000255977(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168|genbank_protein_gi:21359891(identity)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	intact-crc:1BA5EFB8CFA81687|rigid:aOrS/p6aXZhGIZqVfU4JIa4gWbs	false	sufficient binding region:434-482..482	sufficient binding region:1-628	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBL3	uniprotkb:Q5VTT5	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	intact:EBI-5653225|uniprotkb:Q8NA11|uniprotkb:Q6AWC0|uniprotkb:Q6ZRG7|uniprotkb:A6NF75|uniprotkb:Q7Z3G9|uniprotkb:Q6AWC1|uniprotkb:Q96C54|uniprotkb:Q6NXF9|uniprotkb:Q5VTT6|ensembl:ENSP00000363557	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:myom3_human(display_long)|uniprotkb:Myomesin family member 3(gene name synonym)|uniprotkb:MYOM3(gene name)|psi-mi:MYOM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654497|imex:IM-16425-155	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	refseq:NP_689585.3|ensembl:ENSG00000142661(gene)|ensembl:ENST00000374434(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0031430"(M band)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|genbank_protein_gi:40255105(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	rogid:3cBvAjX/bvUZPzI1J3zRE05/vTk9606	intact-crc:FB34B7A1B2EE2BF6|rigid:J+J5jDbnR7LZy0ja8a8sfhal54E	false	sufficient binding region:1-628	sufficient binding region:713-1437(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15291	uniprotkb:Q9UBL3	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654516|imex:IM-16425-156	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|genbank_protein_gi:53759147(identity)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	intact-crc:5923BE5DA17BE70D|rigid:rm9nWy9ujdRhhLm4gVOUvtxlQms	false	sufficient binding region:323-538	sufficient binding region:1-628	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBL3	uniprotkb:Q8WZ42	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654533|imex:IM-16425-157	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:51A4622AC41A0B24|rigid:ScWomsXY8PQTuVjDaaKi79+VZ5M	false	sufficient binding region:1-628	sufficient binding region:30708-34350(IPR002016)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NR09	uniprotkb:P63244	intact:EBI-1765160|uniprotkb:Q9ULD1|ensembl:ENSP00000393596	intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	psi-mi:birc6_human(display_long)|uniprotkb:BIRC6(gene name)|psi-mi:BIRC6(display_short)|uniprotkb:KIAA1289(gene name synonym)|uniprotkb:Ubiquitin-conjugating BIR domain enzyme apollon(gene name synonym)|uniprotkb:BIR repeat-containing ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC6(gene name synonym)	psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654605|imex:IM-16425-161	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057336.3|ensembl:ENSG00000115760(gene)|ensembl:ENST00000421745(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051301"(cell division)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0060712"(spongiotrophoblast layer development)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0090543"(Flemming body)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022103|mint:Q9NR09|rcsb pdb:3CEG|genbank_protein_gi:61744455(identity)	rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N|genbank_protein_gi:83641897(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/EZap+9dFkEnO5fRsbzriORwllk9606	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	intact-crc:D4C5E0EEF5F8C865|rigid:YnKBNJ11NEsygxXMfkU/yxaB624	false	sufficient binding region:370-1648	sufficient binding region:187-317(IPR001680)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15822	uniprotkb:P54253	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698	intact:EBI-930964|uniprotkb:Q17S02|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|ensembl:ENSP00000244769|ensembl:ENSP00000416360	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654570|imex:IM-16425-159	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002105.3|ensembl:ENSG00000095951(gene)|ensembl:ENST00000379388(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|genbank_protein_gi:116805341(identity)	refseq:NP_000323.2|refseq:NP_001121636.1|dip:DIP-35353N|ensembl:ENSG00000124788(gene)|ensembl:ENST00000244769(transcript)|ensembl:ENST00000436367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016363"(nuclear matrix)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035176"(social behavior)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051168"(nuclear export)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR036096|interpro:IPR040172|interpro:IPR043404|mint:P54253|rcsb pdb:1OA8|rcsb pdb:2M41|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6QIU|genbank_protein_gi:51479157(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rugwzqsTO0X8mJ5Zy3msTqc6dr09606	rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606	intact-crc:1245DEEADAC2E2B8|rigid:6KekomA7CJJhAYyeK+L8qPy0J2Q	false	sufficient binding region:2288-2718	sufficient binding region:1-815	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBL3	uniprotkb:Q8WZ42	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654552|imex:IM-16425-158	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|genbank_protein_gi:34193485(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:819652DA9DFF49F4|rigid:ScWomsXY8PQTuVjDaaKi79+VZ5M	false	sufficient binding region:1-628	sufficient binding region:29222-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TBK2	uniprotkb:P54253	intact:EBI-3863032|uniprotkb:A8K380|uniprotkb:B5ME38|uniprotkb:Q9H787|ensembl:ENSP00000219315	intact:EBI-930964|uniprotkb:Q17S02|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|ensembl:ENSP00000244769|ensembl:ENSP00000416360	psi-mi:setd6_human(display_long)|uniprotkb:SETD6(gene name)|psi-mi:SETD6(display_short)|uniprotkb:SET domain-containing protein 6(gene name synonym)	psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654587|imex:IM-16425-160	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153777.1|refseq:NP_079136.2|ensembl:ENSG00000103037(gene)|ensembl:ENST00000219315(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR001214(SET)|interpro:IPR011383(RuBisCO-cytochrome methylase, RMS1)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044430|mint:Q8TBK2|rcsb pdb:3QXY|rcsb pdb:3RC0|reactome:R-HSA-3214841|genbank_protein_gi:13376287(identity)	refseq:NP_000323.2|refseq:NP_001121636.1|dip:DIP-35353N|ensembl:ENSG00000124788(gene)|ensembl:ENST00000244769(transcript)|ensembl:ENST00000436367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016363"(nuclear matrix)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035176"(social behavior)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051168"(nuclear export)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR036096|interpro:IPR040172|interpro:IPR043404|mint:P54253|rcsb pdb:1OA8|rcsb pdb:2M41|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6QIU|genbank_protein_gi:51479157(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:1rElWp+bPTbTW+AIwuGFyv9ZGeI9606	rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606	intact-crc:A5845C6FDAEAF277|rigid:ZE1rqTBnbmWyYkSEQLhqZNruVrk	false	sufficient binding region:223-473(IPR001214)	sufficient binding region:1-815	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:P68032	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654649|imex:IM-16425-163	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026|genbank_protein_gi:46411161(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606	intact-crc:62E3B48868CB2EE2|rigid:hSuLGNe7xaH5cGYGOLjtBOScVuo	false	sufficient binding region:16-333	sufficient binding region:4-377	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P18206	uniprotkb:Q9NR09	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998	intact:EBI-1765160|uniprotkb:Q9ULD1|ensembl:ENSP00000393596	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	psi-mi:birc6_human(display_long)|uniprotkb:BIRC6(gene name)|psi-mi:BIRC6(display_short)|uniprotkb:KIAA1289(gene name synonym)|uniprotkb:Ubiquitin-conjugating BIR domain enzyme apollon(gene name synonym)|uniprotkb:BIR repeat-containing ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC6(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654623|imex:IM-16425-162	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003364.1|refseq:NP_054706.1|ensembl:ENSG00000035403(gene)|ensembl:ENST00000211998(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|go:"GO:0005198"(structural molecule activity)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043297"(apical junction assembly)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048675"(axon extension)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|ensembl:ENSP00000211998|ensembl:ENST00000372755|ensembl:ENSP00000361841|dip:DIP-35570N|genbank_protein_gi:50593538(identity)	refseq:NP_057336.3|ensembl:ENSG00000115760(gene)|ensembl:ENST00000421745(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051301"(cell division)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0060712"(spongiotrophoblast layer development)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0090543"(Flemming body)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022103|mint:Q9NR09|rcsb pdb:3CEG|genbank_protein_gi:61744455(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	rogid:/EZap+9dFkEnO5fRsbzriORwllk9606	intact-crc:2923AD571205DA02|rigid:g0//U2oXihtsXUk6wiMnF0zd7+c	false	sufficient binding region:945-1134	sufficient binding region:370-1648	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23109	uniprotkb:P0C862	intact:EBI-2959675|ensembl:ENSP00000358551|ensembl:ENSP00000430075|uniprotkb:Q5TF00|uniprotkb:A8K5N4|uniprotkb:B2RAM1|uniprotkb:F2Z3B3|uniprotkb:Q5TF02	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	psi-mi:ampd1_human(display_long)|uniprotkb:AMPD1(gene name)|psi-mi:AMPD1(display_short)|uniprotkb:AMP deaminase isoform M(gene name synonym)|uniprotkb:Myoadenylate deaminase(gene name synonym)	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654666|imex:IM-16425-164	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000027.2|ensembl:ENSG00000116748(gene)|ensembl:ENST00000369538(transcript)|ensembl:ENST00000520113(transcript)|go:"GO:0003876"(AMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006188"(IMP biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032264"(IMP salvage)|go:"GO:0042802"(identical protein binding)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006329(AMP deaminase)|interpro:IPR032466|reactome:R-HSA-74217|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR029770|refseq:NP_001166097.1|genbank_protein_gi:4557310(identity)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:TBIoFTSOl49LBei4MFGCbbvgF0w9606	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	intact-crc:84AA7FC64688843E|rigid:ww0XZAZUytHIaP7yBXVHLz97O4A	false	sufficient binding region:351-780	sufficient binding region:16-333	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:Q7Z401	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-1046479|ensembl:ENSP00000396830|uniprotkb:Q14655|uniprotkb:Q86T77|uniprotkb:Q8IVX2|uniprotkb:Q8NB93|uniprotkb:E7EPL3	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:mycpp_human(display_long)|uniprotkb:DENN domain-containing protein 4A(gene name synonym)|uniprotkb:DENND4A(gene name)|psi-mi:DENND4A(display_short)|uniprotkb:IRLB(gene name synonym)|uniprotkb:MYCPBP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654700|imex:IM-16425-166	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	ensembl:ENST00000431932(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|interpro:IPR001194(DENN)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023341|interpro:IPR037516|ensembl:ENSG00000174485(gene)|mint:Q7Z401|reactome:R-HSA-8876198|refseq:NP_001138295.1|refseq:NP_005839.3|refseq:XP_005254178.1|refseq:XP_016877352.1|genbank_protein_gi:125628676(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:mZfgls9XVdT2fGgjJ6y2Q8RumoU9606	intact-crc:39DBC473F943BE09|rigid:qQ7mn52axgTsIiOJbGwRGrRBViw	false	sufficient binding region:16-333	sufficient binding region:1297-1863	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:Q9UKG1	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654683|imex:IM-16425-165	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:8E2C68E2DE40B782|rigid:kNA0jzJjzYwtFbMJOHr6vCie1Zs	false	sufficient binding region:16-333	sufficient binding region:381-709	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46976	uniprotkb:P0C862	intact:EBI-740533|uniprotkb:Q9UNV0|uniprotkb:Q6FHZ1|uniprotkb:D3DNH1|uniprotkb:D3DNH2|ensembl:ENSP00000340736|uniprotkb:D3DNH0	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	psi-mi:glyg_human(display_long)|uniprotkb:GYG1(gene name)|psi-mi:GYG1(display_short)|uniprotkb:GYG(gene name synonym)	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654753|imex:IM-16425-169	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171649.1|refseq:NP_001171650.1|refseq:NP_004121.2|go:"GO:0008466"(glycogenin glucosyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0102751"("UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity")|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002495(Glycosyl transferase, family 8)|interpro:IPR029044|rcsb pdb:3Q4S|rcsb pdb:3QVB|rcsb pdb:3RMV|rcsb pdb:3RMW|rcsb pdb:3T7M|rcsb pdb:3T7N|rcsb pdb:3T7O|rcsb pdb:3U2T|rcsb pdb:3U2U|rcsb pdb:3U2V|rcsb pdb:3U2W|rcsb pdb:3U2X|rcsb pdb:6EQJ|rcsb pdb:6EQL|reactome:R-HSA-3322077|reactome:R-HSA-3785653|reactome:R-HSA-3814836|reactome:R-HSA-3828062|reactome:R-HSA-5357609|reactome:R-HSA-6798695|reactome:R-HSA-70221|ensembl:ENSG00000163754(gene)|ensembl:ENST00000345003(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|genbank_protein_gi:976399(identity)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:sSaQ4ewOz4lA4S7cE95pBHW/lyU9606	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	intact-crc:9482D2447C356A2D|rigid:+ZcYtZLQZcrc1/GGSGacR6+aurw	false	sufficient binding region:1-350	sufficient binding region:16-333	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:P78344	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-296519|uniprotkb:O60877|uniprotkb:P78404|uniprotkb:Q0VH00|uniprotkb:Q53EU1|uniprotkb:Q58EZ2|uniprotkb:Q8NI71|uniprotkb:Q96C16|ensembl:ENSP00000340281|ensembl:ENSP00000433371|ensembl:ENSP00000433664|uniprotkb:Q0VH01|uniprotkb:Q2NKW9|uniprotkb:Q49A79	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:if4g2_human(display_long)|uniprotkb:EIF4G2(gene name)|psi-mi:EIF4G2(display_short)|uniprotkb:DAP5(gene name synonym)|uniprotkb:OK/SW-cl.75(orf name)|uniprotkb:p97(gene name synonym)|uniprotkb:Death-associated protein 5(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654735|imex:IM-16425-168	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	ensembl:ENSG00000110321(gene)|ensembl:ENST00000339995(transcript)|ensembl:ENST00000525681(transcript)|ensembl:ENST00000526148(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007507"(heart development)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008219"(cell death)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:P78344|rcsb pdb:3D3M|rcsb pdb:3L6A|rcsb pdb:4IUL|reactome:R-HSA-1169408|refseq:NP_001036024.3|refseq:NP_001166176.1|refseq:NP_001409.3|dip:DIP-31366N|genbank_protein_gi:34782923(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:UIE1Um0s2KJ9hpaa9X6kfZ8enPc9606	intact-crc:2F3434BA603BED6A|rigid:tStsscbgWxPxz01pleevdPNjggc	false	sufficient binding region:16-333	sufficient binding region:200-907(IPR003307)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03001	uniprotkb:P0C862	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654717|imex:IM-16425-167	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	intact-crc:4D1361B3A9216332|rigid:XLvXa4Z7HRmFIy6HqPJZPXRRyHk	false	sufficient binding region:4170-7570(IPR002017)	sufficient binding region:16-333	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:P52179	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-5353249|uniprotkb:Q14BD6|uniprotkb:Q6H969|uniprotkb:Q6ZUU0|ensembl:ENSP00000348821	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:myom1_human(display_long)|uniprotkb:MYOM1(gene name)|psi-mi:MYOM1(display_short)|uniprotkb:190 kDa connectin-associated protein(gene name synonym)|uniprotkb:190 kDa titin-associated protein(gene name synonym)|uniprotkb:Myomesin family member 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654806|imex:IM-16425-172	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	dip:DIP-59649N|refseq:NP_003794.3|refseq:NP_062830.1|ensembl:ENSG00000101605(gene)|ensembl:ENST00000356443(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P52179|rcsb pdb:2R15|rcsb pdb:2Y23|rcsb pdb:2Y25|rcsb pdb:3RBS|rcsb pdb:5FM4|rcsb pdb:5FM5|rcsb pdb:5FM8|rcsb pdb:6T3O|genbank_protein_gi:46249363(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:5lfd5o+54eyer647zxvU0LX1wpM9606	intact-crc:0C7C0C97E68189E8|rigid:YOBCCkMpEc/LbfiAjYEmiykz8ew	false	sufficient binding region:16-333	sufficient binding region:1242-1685..1685(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q00872	uniprotkb:P0C862	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654788|imex:IM-16425-171	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	intact-crc:56E4E94550F444AB|rigid:xv2vVJZz+Ch6kMKP7y5pAHhcpVg	false	sufficient binding region:608-1141(IPR003961)	sufficient binding region:16-333	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92615	uniprotkb:P0C862	intact:EBI-1052558|uniprotkb:Q5T3R3|uniprotkb:Q5T3R4|uniprotkb:Q5T3R5|uniprotkb:Q68CY4|uniprotkb:A7MD20|intact:EBI-28969094|ensembl:ENSP00000326128	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	psi-mi:lar4b_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:LARP4B(gene name)|psi-mi:LARP4B(display_short)|uniprotkb:LARP5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym)|uniprotkb:KIAA0217(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym)	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654770|imex:IM-16425-170	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055970.1|ensembl:ENSP00000326128|ensembl:ENSG00000107929(gene)|ensembl:ENST00000316157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034900|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3PTH|genbank_protein_gi:57634535(identity)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:tVFpPu0vhCgdRt0lowfi5GzA8Do9606	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	intact-crc:091DFF1620F3EBE0|rigid:rUldA9vHCb6cdCoZ/wVzbNTD2wM	false	sufficient binding region:108-738(IPR006630)	sufficient binding region:16-333	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:P28331	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654842|imex:IM-16425-174	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1|genbank_protein_gi:33519474(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606	intact-crc:0EE3CC646287B6A0|rigid:dtenZ2ifn51D5AWgLQg7Bd8L0xM	false	sufficient binding region:16-333	sufficient binding region:216-727(IPR006656)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:P55209	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654824|imex:IM-16425-173	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|genbank_protein_gi:33876637(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	intact-crc:B2DCAAC027129648|rigid:j4DxgV8WH65pamZFXmWidD93FB0	false	sufficient binding region:16-333	sufficient binding region:21-391(IPR002164)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:P46939	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654896|imex:IM-16425-177	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665|genbank_protein_gi:110611227(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	intact-crc:F2746B8BDC0F1C28|rigid:t12VMhj4eOYShv8/FXBa8Zx2JY8	false	sufficient binding region:16-333	sufficient binding region:2407-3433(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P0C862	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654877|imex:IM-16425-176	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	intact-crc:55616917D78574F3|rigid:OVuVX4x37io54BJQSho8ZRkaZ8o	false	sufficient binding region:30425-34350(IPR00396)	sufficient binding region:16-333	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:P35241	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-2514878|ensembl:ENSP00000496503|uniprotkb:Q86Y61|uniprotkb:A7YIK0|uniprotkb:A7YIK3|uniprotkb:A7YIJ8|uniprotkb:B7Z9U6|uniprotkb:F5H1A7	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:radi_human(display_long)|uniprotkb:RDX(gene name)|psi-mi:RDX(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654860|imex:IM-16425-175	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	ensembl:ENSG00000137710(gene)|ensembl:ENST00000645495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:1903392"(negative regulation of adherens junction organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35241|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_002897.1|refseq:NP_001247423.1|refseq:NP_001247424.1|refseq:NP_001247425.1|refseq:NP_001247421.1|refseq:NP_001247422.1|genbank_protein_gi:28436808(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:75lzbINdL0deHtiWY7IwioSh5749606	intact-crc:34CEB1F0B77AFF06|rigid:lGQEVmmFxxePUyrNDsUWsqYqSMA	false	sufficient binding region:16-333	sufficient binding region:168-583	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y376	uniprotkb:O00410	intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125	psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654943|imex:IM-16425-179	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|genbank_protein_gi:7764081(identity)	refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N|genbank_protein_gi:51873051(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	intact-crc:E9EA35FF3DEC22E4|rigid:8VSS5j6s83/8sX+jadPklEZ4O/s	false	sufficient binding region:1-341	sufficient binding region:1008-1097	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:Q9C0G0	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-5654914|uniprotkb:Q9H8A1|uniprotkb:Q96MY0|uniprotkb:B5MD54|uniprotkb:Q9NXD7|uniprotkb:Q9NXD4|ensembl:ENSP00000299687	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:zn407_human(display_long)|uniprotkb:KIAA1703(gene name synonym)|uniprotkb:ZNF407(gene name)|psi-mi:ZNF407(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654925|imex:IM-16425-178	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	refseq:XP_011524372.1|refseq:XP_011524370.1|refseq:NP_001139661.1|refseq:NP_001139662.1|refseq:NP_060227.2|refseq:XP_005266783.1|ensembl:ENSG00000215421(gene)|ensembl:ENST00000299687(transcript)|interpro:IPR036236|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|genbank_protein_gi:7020314(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:1IwRCT+v3qYg2Ii3jabVzznKu8Y9606	intact-crc:E71A43F4186469C0|rigid:9LK3Nr4StkZjT7M8NTex9ocxDtc	false	sufficient binding region:16-333	sufficient binding region:453-2248(IPR007087)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20807	uniprotkb:P02511	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654995|imex:IM-16425-182	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|genbank_protein_gi:256398(identity)	-	-	crc64:AE08BED46B7849CB	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	rogid:495Z42oQhkAUdADrAEOKIC5oICo9606	intact-crc:F31B07323875CD48|rigid:OvCv56QzEFzhQqQOVso8YrMPb90	false	sufficient binding region:417-643	sufficient binding region:66-175(IPR002068)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y376	uniprotkb:Q9C0K7	intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7	intact:EBI-306893|uniprotkb:Q5BKY7|uniprotkb:Q9P1L0|ensembl:ENSP00000194530	psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym)	psi-mi:strab_human(display_long)|uniprotkb:STRADB(gene name)|psi-mi:STRADB(display_short)|uniprotkb:ILPIP(gene name synonym)|uniprotkb:Pseudokinase ALS2CR2(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein(gene name synonym)|uniprotkb:ALS2CR2(gene name synonym)|uniprotkb:ILP-interacting protein(gene name synonym)|uniprotkb:CALS-21(gene name synonym)|uniprotkb:PRO1038(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654978|imex:IM-16425-181	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|genbank_protein_gi:7764081(identity)	refseq:NP_001193793.1|refseq:NP_061041.2|refseq:XP_016859927.1|ensembl:ENSG00000082146(gene)|ensembl:ENST00000194530(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007254"(JNK cascade)|go:"GO:0016235"(aggresome)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|reactome:R-HSA-380972|genbank_protein_gi:21359970(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606	rogid:0oXeswkNLoFV4PTC1f9DYRKJpVk9606	intact-crc:5C7DD0902DEFF642|rigid:nu600MQ+83BOTUn4u6DMqcx/Hhk	false	sufficient binding region:1-341	sufficient binding region:404-418..418	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76021	uniprotkb:Q9Y376	intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871	intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7	psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym)	psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5654960|imex:IM-16425-180	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021|genbank_protein_gi:118498358(identity)	go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|genbank_protein_gi:7764081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606	rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606	intact-crc:DB7576FCB6B6932C|rigid:zi9qRJPTyJsFac+teYqGE1qygd8	false	sufficient binding region:9-490(IPR002143)	sufficient binding region:1-341	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20807	uniprotkb:Q9Y244	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655022|imex:IM-16425-183	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	intact-crc:1A881FFA497F61E7|rigid:RSnCsrvs07OeMGsOSq2/cM6/PNs	false	sufficient binding region:417-643	sufficient binding region:1-141..141(IPR008012)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0C862	uniprotkb:P20807	intact:EBI-5654640|uniprotkb:Q8IUU4|uniprotkb:Q5VX65|uniprotkb:A2A3T6|uniprotkb:Q5VX66|uniprotkb:Q0VGC5|ensembl:ENSP00000333737|ensembl:ENSP00000371503	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	psi-mi:c1t9a_human(display_long)|uniprotkb:C1QTNF9A(gene name synonym)|uniprotkb:Complement C1q and tumor necrosis factor-related protein 9(gene name synonym)|uniprotkb:UNQ6503/PRO21380(orf name)|uniprotkb:C1QTNF9(gene name)|psi-mi:C1QTNF9(display_short)	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655075|imex:IM-16425-186	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290066.1|refseq:NP_001290067.1|refseq:NP_848635.2|ensembl:ENSG00000240654(gene)|ensembl:ENST00000332018(transcript)|ensembl:ENST00000382071(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0042802"(identical protein binding)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|genbank_protein_gi:31341752(identity)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:U1j8g9PsKiblCJ22gySY5UK2lOQ9606	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	intact-crc:19FFE64E78D61C1B|rigid:jDlQwtGutGm7dfnLPptvdPifRuQ	false	sufficient binding region:230-333..333(IPR001073)	sufficient binding region:417-643	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q4VCS5	uniprotkb:P20807	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655058|imex:IM-16425-185	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N|genbank_protein_gi:63252911(identity)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	intact-crc:9F9DE37619FE0D9A|rigid:R+Vi0/y+iPLL2Nx6S4wjJyVsdcY	false	sufficient binding region:248-1084	sufficient binding region:417-643	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P20807	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655040|imex:IM-16425-184	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	intact-crc:E7AB67ECD085EE64|rigid:H55HQ/yf2LPaQAzVqvKFJwoYxyk	false	sufficient binding region:33080-34350(IPR007110)	sufficient binding region:417-643	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20807	uniprotkb:Q53EP0	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	intact:EBI-2847708|uniprotkb:Q6PIJ3|uniprotkb:B2RB36|uniprotkb:Q8NBU7|uniprotkb:Q6UXG1|uniprotkb:B3KXR8|uniprotkb:Q5U5T8|uniprotkb:Q9H5I7|uniprotkb:Q8IXB2|uniprotkb:Q9NSQ8|uniprotkb:Q96D78|uniprotkb:Q6UXZ5|uniprotkb:D3DNQ7|ensembl:ENSP00000338523|ensembl:ENSP00000389094|ensembl:ENSP00000411242	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:fnd3b_human(display_long)|uniprotkb:FNDC3B(gene name)|psi-mi:FNDC3B(display_short)|uniprotkb:FAD104(gene name synonym)|uniprotkb:NS5ABP37(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 104(gene name synonym)|uniprotkb:HCV NS5A-binding protein 37(gene name synonym)|uniprotkb:UNQ2421/PRO4979/PRO34274(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655111|imex:IM-16425-188	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	refseq:NP_001128567.1|refseq:NP_073600.3|ensembl:ENSP00000338523|ensembl:ENSP00000411242|ensembl:ENSP00000389094|ensembl:ENST00000421757|ensembl:ENSP00000408496|ensembl:ENST00000423424|ensembl:ENSP00000392471|ensembl:ENSG00000075420(gene)|ensembl:ENST00000336824(transcript)|ensembl:ENST00000415807(transcript)|ensembl:ENST00000416957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:Q53EP0|genbank_protein_gi:27477058(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	rogid:a8Yk/79adiuueOBYtKZSPnN71u09606	intact-crc:E632B4AA96F4B82E|rigid:r4N9dFm84AEax78NJP+sx3LOG2o	false	sufficient binding region:417-643	sufficient binding region:571-1204(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3K9	uniprotkb:P20807	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655093|imex:IM-16425-187	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9|genbank_protein_gi:62241002(identity)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	intact-crc:332A4BD7808D900D|rigid:cP/St3iij28pZO53OwkAqFC8CXg	false	sufficient binding region:3489-4069(IPR003961)	sufficient binding region:417-643	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20807	uniprotkb:Q13203	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	intact:EBI-5655165|uniprotkb:Q86YC5|uniprotkb:Q16886|ensembl:ENSP00000255416	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:mybph_human(display_long)|uniprotkb:H-protein(gene name synonym)|uniprotkb:MYBPH(gene name)|psi-mi:MYBPH(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655171|imex:IM-16425-191	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	refseq:NP_004988.2|ensembl:ENSG00000133055(gene)|ensembl:ENST00000255416(transcript)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|genbank_protein_gi:28277416(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	rogid:G72i8b794rZ+W4VeZ7oCNuowG2I9606	intact-crc:DC362EE6D782DB16|rigid:o85jn1/oB0LXKi/7Nt1rQLr29Ak	false	sufficient binding region:417-643	sufficient binding region:216-477(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20807	uniprotkb:Q00872	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655147|imex:IM-16425-190	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:F4CCCD369371A334|rigid:dFDMFZ+nUnAfSAYHxQde1XS4t1o	false	sufficient binding region:417-643	sufficient binding region:281-1141(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08253	uniprotkb:P20807	intact:EBI-1033518|uniprotkb:B2R6U1|uniprotkb:Q9UCJ8|ensembl:ENSP00000219070|uniprotkb:E9PE45|uniprotkb:B4DWH3	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	psi-mi:mmp2_human(display_long)|uniprotkb:MMP2(gene name)|psi-mi:MMP2(display_short)|uniprotkb:CLG4A(gene name synonym)|uniprotkb:72 kDa gelatinase(gene name synonym)|uniprotkb:Matrix metalloproteinase-2(gene name synonym)|uniprotkb:Gelatinase A(gene name synonym)|uniprotkb:TBE-1(gene name synonym)	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655129|imex:IM-16425-189	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001289437.1|refseq:NP_001289438.1|refseq:NP_001289439.1|ensembl:ENSG00000087245(gene)|ensembl:ENST00000219070(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007566"(embryo implantation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030017"(sarcomere)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048771"(tissue remodeling)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR024079|interpro:IPR028708|interpro:IPR033739|interpro:IPR036365|interpro:IPR036375|interpro:IPR036943|rcsb pdb:1CK7|rcsb pdb:1CXW|rcsb pdb:1EAK|rcsb pdb:1GEN|rcsb pdb:1GXD|rcsb pdb:1HOV|rcsb pdb:1J7M|rcsb pdb:1KS0|rcsb pdb:1QIB|rcsb pdb:1RTG|rcsb pdb:3AYU|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-381426|reactome:R-HSA-3928665|reactome:R-HSA-6785807|reactome:R-HSA-9009391|refseq:NP_001121363.1|refseq:NP_004521.1|genbank_protein_gi:11342665(identity)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:s0IHoSkzT9GNfkkLZsVsV7cIf1g9606	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	intact-crc:5D3EA2BD308AB88C|rigid:0a5tVoFaDFsNpPKjYhxOQGj0pS4	false	sufficient binding region:434-660(IPR000585)	sufficient binding region:417-643	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20807	uniprotkb:P17980	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	intact:EBI-359720|uniprotkb:Q3B757|ensembl:ENSP00000298852|ensembl:ENSP00000481029|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655206|imex:IM-16425-193	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	refseq:NP_002795.2|ensembl:ENSG00000165916(gene)|ensembl:ENST00000298852(transcript)|ensembl:ENST00000619920(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|go:"GO:0036402"(proteasome-activating activity)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-1236978|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27555N|genbank_protein_gi:133987588(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606	intact-crc:29A3F384EFE53CE7|rigid:iXCEsS2E+xq7e25ugYjVxq7b+Ig	false	sufficient binding region:417-643	sufficient binding region:43-439	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q4J6C6	uniprotkb:P20807	intact:EBI-949331|uniprotkb:A7E2X6|uniprotkb:O43163|uniprotkb:Q4J6C3|uniprotkb:Q4J6C4|uniprotkb:Q4ZG39|uniprotkb:Q6ZMW7|uniprotkb:Q96DW7|uniprotkb:D6W5A3|ensembl:ENSP00000260648|ensembl:ENSP00000386509|ensembl:ENSP00000386543|ensembl:ENSP00000386909|ensembl:ENSP00000391456|ensembl:ENSP00000409480	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	psi-mi:ppcel_human(display_long)|uniprotkb:KIAA0436(gene name synonym)|uniprotkb:Prolylendopeptidase-like(gene name synonym)|uniprotkb:PREPL(gene name)|psi-mi:PREPL(display_short)	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655189|imex:IM-16425-192	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035844.1|refseq:NP_001035845.1|refseq:NP_001165074.1|refseq:NP_001165077.1|refseq:NP_001165084.1|refseq:NP_001165088.1|refseq:NP_006027.2|refseq:XP_011531500.1|refseq:XP_011531502.1|refseq:XP_011531504.1|refseq:XP_016860873.1|refseq:XP_016860874.1|ensembl:ENSG00000138078(gene)|ensembl:ENST00000260648(transcript)|ensembl:ENST00000409272(transcript)|ensembl:ENST00000409936(transcript)|ensembl:ENST00000410081(transcript)|ensembl:ENST00000425263(transcript)|ensembl:ENST00000426481(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008233"(peptidase activity)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002470(Peptidase S9A, prolyl oligopeptidase)|interpro:IPR023302|interpro:IPR029058|genbank_protein_gi:108860687(identity)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:xn++9zR6AX/HzP4KzrriJR5IUTk9606	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	intact-crc:4B82C28E137DE723|rigid:YI2hG+YDJRJfr2AUUvQDXA2I5qY	false	sufficient binding region:421-727..727	sufficient binding region:417-643	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P20807	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655258|imex:IM-16425-196	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	intact-crc:5725149E37DF1064|rigid:H55HQ/yf2LPaQAzVqvKFJwoYxyk	false	sufficient binding region:29829-34350(IPR003961)	sufficient binding region:417-643	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H6Y7	uniprotkb:P20807	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655240|imex:IM-16425-195	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1|genbank_protein_gi:14149701(identity)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	intact-crc:5E56E9A44E4C9F34|rigid:9ZjG9oFeI6ceKreBjPZ6U5TlML8	false	sufficient binding region:219-350..350(IPR001841)	sufficient binding region:417-643	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20807	uniprotkb:Q99460	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	intact:EBI-357874|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79|ensembl:ENSP00000309474|ensembl:ENSP00000503068	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655223|imex:IM-16425-194	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-382556|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_protein_gi:25777599(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606	intact-crc:02963C8F5ABF820C|rigid:AVFDSkA2POSk833tRonk4YkLKmU	false	sufficient binding region:417-643	sufficient binding region:36-953	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14732	uniprotkb:P40227	intact:EBI-725233|uniprotkb:Q9UJT3|uniprotkb:B0YJ29|ensembl:ENSP00000269159	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:impa2_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 2"(gene name synonym)|uniprotkb:Myo-inositol monophosphatase A2(gene name synonym)|uniprotkb:IMPA2(gene name)|psi-mi:IMPA2(display_short)|uniprotkb:IMP.18P(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655294|imex:IM-16425-198	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055029.1|ensembl:ENSG00000141401(gene)|ensembl:ENST00000269159(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:2CZH|rcsb pdb:2CZI|rcsb pdb:2CZK|rcsb pdb:2DDK|rcsb pdb:2FVZ|reactome:R-HSA-1855183|genbank_protein_gi:16877898(identity)	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|genbank_protein_gi:58331169(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aNPodNmy97DStapDoe+oOkCD8X49606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:9FF5C88EBA04E741|rigid:IENSy4z1fbaWCn3JXEjw5RyT+yo	false	sufficient binding region:17-288(IPR000760)	sufficient binding region:1-530	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P20807	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5655000|ensembl:ENSP00000380349|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655276|imex:IM-16425-197	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	ensembl:ENSG00000092529(gene)|ensembl:ENST00000397163(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030239"(myofibril assembly)|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|go:"GO:0030315"(T-tubule)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031432"(titin binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055103"(ligase regulator activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061061"(muscle structure development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097264"(self proteolysis)|go:"GO:1990092"(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P20807|rcsb pdb:1Y9V|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|genbank_protein_gi:27765081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	intact-crc:4D037065B9C48493|rigid:H55HQ/yf2LPaQAzVqvKFJwoYxyk	false	sufficient binding region:8641-34350(IPR003599)	sufficient binding region:417-643	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40227	uniprotkb:Q14324	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655347|imex:IM-16425-201	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|genbank_protein_gi:58331169(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:33861C239E5DD44B|rigid:TOgYKxS3lfl3VJWWSNSRsguqTOQ	false	sufficient binding region:1-530	sufficient binding region:934-1141(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UH92	uniprotkb:P40227	intact:EBI-741109|intact:EBI-28976799|ensembl:ENSP00000246912|uniprotkb:Q53XM6|uniprotkb:Q96FL2|uniprotkb:Q9H2V0|uniprotkb:Q9H2V1|uniprotkb:Q9H2V2|uniprotkb:Q9NXN3|uniprotkb:B2RAV8|uniprotkb:A8K2J3|uniprotkb:B2RD73	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:mlx_human(display_long)|uniprotkb:Max-like bHLHZip protein(gene name synonym)|uniprotkb:BHLHD13(gene name synonym)|uniprotkb:Protein BigMax(gene name synonym)|uniprotkb:Transcription factor-like protein 4(gene name synonym)|uniprotkb:MLX(gene name)|psi-mi:MLX(display_short)|uniprotkb:TCFL4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 13(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655329|imex:IM-16425-200	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_733752.1|refseq:NP_937847.1|refseq:NP_937848.1|ensembl:ENSG00000108788(gene)|ensembl:ENST00000246912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032647|interpro:IPR036638|reactome:R-HSA-163765|go:"GO:0005654"(nucleoplasm)|ensembl:ENSP00000246912|ensembl:ENST00000346833|ensembl:ENSP00000320913|ensembl:ENST00000435881|ensembl:ENSP00000416627|genbank_protein_gi:38201611(identity)	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|genbank_protein_gi:58331169(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5zIr/dC+5Gre7BiEy/8g0MEdppY9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:C18D19CF797B31AE|rigid:HKnk5vQc1qDKxjvHRWx4VZtsSDw	false	sufficient binding region:3-298(IPR001092)	sufficient binding region:1-530	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40227	uniprotkb:P29375	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655312|imex:IM-16425-199	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|genbank_protein_gi:58331169(identity)	refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842|genbank_protein_gi:110618243(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606	intact-crc:94C35E48E2DE9FC0|rigid:Dmg4MHkW0ayO4V/QzhWkxPFFRl0	false	sufficient binding region:1-530	sufficient binding region:1329-1690	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40227	uniprotkb:Q9Y5B9	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	intact:EBI-1046849|uniprotkb:Q6GMT8|uniprotkb:Q6P2F1|uniprotkb:Q6PJM1|uniprotkb:Q9NRX0|ensembl:ENSP00000216297	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:sp16h_human(display_long)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:SUPT16H(gene name)|psi-mi:SUPT16H(display_short)|uniprotkb:FACT140(gene name synonym)|uniprotkb:FACTP140(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655382|imex:IM-16425-203	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|genbank_protein_gi:58331169(identity)	ensembl:ENSG00000092201(gene)|ensembl:ENST00000216297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|mint:Q9Y5B9|rcsb pdb:4Z2M|rcsb pdb:4Z2N|rcsb pdb:5E5B|rcsb pdb:5UMT|rcsb pdb:5UMU|rcsb pdb:5XM2|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|refseq:NP_009123.1|dip:DIP-42757N|genbank_protein_gi:19924176(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	rogid:jLK5dOF3mEyI0UbZhcNgtdlG+WI9606	intact-crc:A7C6FF838315541B|rigid:ntF/keYPEOG5iSaatLJLkyE5CbY	false	sufficient binding region:1-530	sufficient binding region:760-1047	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKK3	uniprotkb:P40227	intact:EBI-2623021|uniprotkb:Q5QNZ9|uniprotkb:O75903|uniprotkb:Q14682|uniprotkb:Q9H1M6|ensembl:ENSP00000371419	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:parp4_human(display_long)|uniprotkb:ADPRTL1(gene name synonym)|uniprotkb:KIAA0177(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:193 kDa vault protein(gene name synonym)|uniprotkb:PARP-related/IalphaI-related H5/proline-rich(gene name synonym)|uniprotkb:"Vault poly(ADP-ribose) polymerase"(gene name synonym)|uniprotkb:PARP4(gene name)|psi-mi:PARP4(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 4(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 4(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655365|imex:IM-16425-202	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011533234.1|refseq:NP_006428.2|ensembl:ENSG00000102699(gene)|ensembl:ENST00000381989(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008219"(cell death)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0042493"|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001357(BRCT)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR031273|interpro:IPR036420|interpro:IPR036465|interpro:IPR036616|mint:Q9UKK3|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|genbank_protein_gi:112789549(identity)	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|genbank_protein_gi:58331169(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:d1n+oei4ZSmqUnvJzMe6RLq2XOc9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:6700F38C783B8998|rigid:0hDgRTzqcL3zDUaczJLOc8I5rfg	false	sufficient binding region:1398-1724	sufficient binding region:1-530	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VT25	uniprotkb:Q9Y5S2	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-1043430|uniprotkb:Q2L7A5|uniprotkb:Q86TJ1|uniprotkb:Q9ULU5|ensembl:ENSP00000355237|uniprotkb:A9JR72	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrckb_human(display_long)|uniprotkb:CDC42-binding protein kinase beta(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase beta(gene name synonym)|uniprotkb:DMPK-like beta(gene name synonym)|uniprotkb:CDC42BPB(gene name)|psi-mi:CDC42BPB(display_short)|uniprotkb:KIAA1124(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655434|imex:IM-16425-206	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1|genbank_protein_gi:30089959(identity)	go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSG00000198752(gene)|ensembl:ENST00000361246(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR031597|interpro:IPR033232|interpro:IPR042718|rcsb pdb:3QFV|rcsb pdb:3TKU|rcsb pdb:4UAK|rcsb pdb:4UAL|rcsb pdb:5OTE|rcsb pdb:5OTF|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|refseq:NP_006026.3|genbank_protein_gi:115527096(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:FaheT9htZ/NtYfTKvNDcLqNtQiQ9606	intact-crc:DC465988E3101165|rigid:GMEwDimIF5nUKyEw2ddqjnxqhmw	false	sufficient binding region:978-1638	sufficient binding region:928-1711(IPR002219)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VT25	uniprotkb:Q5VT25	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655417|imex:IM-16425-205	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1|genbank_protein_gi:30089959(identity)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1|genbank_protein_gi:30089959(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:D9A2FF9A98B33D75|rigid:CGRfSRzl/RFPsF2Wdyray8ARi/c	false	sufficient binding region:875-1732	sufficient binding region:978-1638	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P40227	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655399|imex:IM-16425-204	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|genbank_protein_gi:58331169(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:A19112BF0124C71C|rigid:y5zhW/b1jIrO+/TddmiMipFHEcQ	false	sufficient binding region:29427-34350(IPR007110)	sufficient binding region:1-530	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07900	uniprotkb:Q9UHD1	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	intact:EBI-2550959|ensembl:ENSP00000319255|ensembl:ENSP00000496744|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655469|imex:IM-16425-208	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N|genbank_protein_gi:63029936(identity)	ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000320585(transcript)|ensembl:ENST00000646618(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0043531"(ADP binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|rcsb pdb:2YRT|go:"GO:1900034"(regulation of cellular response to heat)|refseq:NP_001137545.1|refseq:NP_036256.2|genbank_protein_gi:6581055(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606	intact-crc:2E4CC9B61EADBB63|rigid:ZsBDH6sK9d9TchmSutsrwMLN8Ak	false	sufficient binding region:162-732(IPR001404)	sufficient binding region:1-332	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VT25	uniprotkb:P21675	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655452|imex:IM-16425-207	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1|genbank_protein_gi:30089959(identity)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N|genbank_protein_gi:20357587(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	intact-crc:EEBD4B2D0D88DF58|rigid:NM0A7O/N44uMjPR7TZzdmK0PT2o	false	sufficient binding region:978-1638	sufficient binding region:1047-1872	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHD1	uniprotkb:P53041	intact:EBI-2550959|ensembl:ENSP00000319255|ensembl:ENSP00000496744|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49	intact:EBI-716663|uniprotkb:Q53XV2|uniprotkb:Q16722|ensembl:ENSP00000012443	psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym)	psi-mi:ppp5_human(display_long)|uniprotkb:Protein phosphatase T(gene name synonym)|uniprotkb:PPP5C(gene name)|psi-mi:PPP5C(display_short)|uniprotkb:PPP5(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655523|imex:IM-16425-211	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000320585(transcript)|ensembl:ENST00000646618(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0043531"(ADP binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|rcsb pdb:2YRT|go:"GO:1900034"(regulation of cellular response to heat)|refseq:NP_001137545.1|refseq:NP_036256.2|genbank_protein_gi:6581055(identity)	refseq:NP_006238.1|ensembl:ENSG00000011485(gene)|ensembl:ENST00000012443(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043204"(perikaryon)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043278"(response to morphine)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0101031"(chaperone complex)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1904550"(response to arachidonic acid)|go:"GO:1990635"(proximal dendrite)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011236(Protein phosphatase 5)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013235(Serine/threonine phosphatase, PPP5)|interpro:IPR019734|interpro:IPR029052|interpro:IPR041753|mint:P53041|rcsb pdb:1A17|rcsb pdb:1S95|rcsb pdb:1WAO|rcsb pdb:2BUG|rcsb pdb:3H60|rcsb pdb:3H61|rcsb pdb:3H62|rcsb pdb:3H63|rcsb pdb:3H64|rcsb pdb:3H66|rcsb pdb:3H67|rcsb pdb:3H68|rcsb pdb:3H69|rcsb pdb:4ZVZ|rcsb pdb:4ZX2|rcsb pdb:5HPE|rcsb pdb:5UI1|rcsb pdb:5WG8|reactome:R-HSA-5675221|reactome:R-HSA-5693565|reactome:R-HSA-8939211|dip:DIP-29043N|genbank_protein_gi:20127496(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606	rogid:5QoNB467ftOvWaUNfSm6RalR8+Y9606	intact-crc:19583DCD770BBFE0|rigid:4wEw9BEXZ8D3FzBX685+bO7Ir1o	false	sufficient binding region:1-332	sufficient binding region:7-499	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHD1	uniprotkb:P55209	intact:EBI-2550959|ensembl:ENSP00000319255|ensembl:ENSP00000496744|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655505|imex:IM-16425-210	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000320585(transcript)|ensembl:ENST00000646618(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0043531"(ADP binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|rcsb pdb:2YRT|go:"GO:1900034"(regulation of cellular response to heat)|refseq:NP_001137545.1|refseq:NP_036256.2|genbank_protein_gi:6581055(identity)	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|genbank_protein_gi:33876637(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	intact-crc:7845A789D7A0C322|rigid:3zHr8lIaVxeUQPTQ0F2pvpV4zi8	false	sufficient binding region:1-332	sufficient binding region:151-391(IPR002164)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08238	uniprotkb:Q9UHD1	intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0	intact:EBI-2550959|ensembl:ENSP00000319255|ensembl:ENSP00000496744|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49	psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym)	psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655487|imex:IM-16425-209	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N|genbank_protein_gi:20149593(identity)	ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000320585(transcript)|ensembl:ENST00000646618(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0043531"(ADP binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|rcsb pdb:2YRT|go:"GO:1900034"(regulation of cellular response to heat)|refseq:NP_001137545.1|refseq:NP_036256.2|genbank_protein_gi:6581055(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wOsW7C10v2oMsM+REE38K6PAan09606	rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606	intact-crc:CA20071A838CEF74|rigid:auHOkRpZulMh1Ysk61uRt4EInkQ	false	sufficient binding region:37-724(IPR001404)	sufficient binding region:1-332	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3C7	uniprotkb:P30622	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	intact:EBI-2683569|uniprotkb:A0AVD3|uniprotkb:Q29RG0|uniprotkb:Q17RS4|ensembl:ENSP00000479322	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:clip1_human(display_long)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655568|imex:IM-16425-213	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	refseq:NP_002947.1|refseq:NP_937883.1|refseq:NP_001234926.1|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR032108|interpro:IPR036859|mint:P30622|rcsb pdb:2CP5|rcsb pdb:2CP6|rcsb pdb:2E3H|rcsb pdb:2E3I|rcsb pdb:2E4H|rcsb pdb:2HQH|rcsb pdb:2QK0|rcsb pdb:3E2U|rcsb pdb:3RDV|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000130779(gene)|ensembl:ENST00000620786(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001726"(ruffle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031116"(positive regulation of microtubule polymerization)|refseq:XP_016875275.1|refseq:XP_016875279.1|dip:DIP-42826N|genbank_protein_gi:38044111(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	rogid:MqpHl9SGApxmKI7HWfN3gxyK3Cg9606	intact-crc:56F4DF2AA84F8037|rigid:eem/re3wd3njf/yQcFD5Bmr6pog	false	sufficient binding region:1-705	sufficient binding region:1098-1438	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3C7	uniprotkb:Q96SN8	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	intact:EBI-308374|uniprotkb:Q7Z3L4|uniprotkb:Q7Z3U1|uniprotkb:Q7Z7I6|uniprotkb:Q9BSW0|uniprotkb:Q9H6J6|uniprotkb:Q9HCD9|uniprotkb:Q9NV90|uniprotkb:Q9UIW9|uniprotkb:Q5JV18|ensembl:ENSP00000343818	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:ck5p2_human(display_long)|uniprotkb:CDK5RAP2(gene name)|psi-mi:CDK5RAP2(display_short)|uniprotkb:KIAA1633(gene name synonym)|uniprotkb:CDK5 activator-binding protein C48(gene name synonym)|uniprotkb:Centrosome-associated protein 215(gene name synonym)|uniprotkb:CEP215(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655551|imex:IM-16425-212	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	refseq:NP_001011649.1|ensembl:ENSG00000136861(gene)|ensembl:ENST00000349780(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR012943(Spindle associated)|mint:Q96SN8|rcsb pdb:6X0V|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_060719.4|refseq:NP_001258968.1|refseq:XP_006717245.1|dip:DIP-31632N|genbank_protein_gi:58535450(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	rogid:/XamYFvD5N/npIkOGnLQkZzmBnU9606	intact-crc:0E73396AC2AD0162|rigid:h/K645LftRXSreGvvpFzHceJ/OA	false	sufficient binding region:1-705	sufficient binding region:1455-1893	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3C7	uniprotkb:P17661	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	intact:EBI-1055572|uniprotkb:Q15787|uniprotkb:Q8IZR1|uniprotkb:Q8IZR6|uniprotkb:Q8NES2|uniprotkb:Q8NEU6|uniprotkb:Q8TAC4|uniprotkb:Q8TCX2|uniprotkb:Q8TD99|uniprotkb:Q9UHN5|uniprotkb:Q9UJ80|uniprotkb:Q549R7|uniprotkb:Q549R8|uniprotkb:Q549R9|ensembl:ENSP00000363071	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:desm_human(display_long)|uniprotkb:DES(gene name)|psi-mi:DES(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655621|imex:IM-16425-216	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	refseq:NP_001918.3|ensembl:ENSG00000175084(gene)|ensembl:ENST00000373960(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005916"(fascia adherens)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|mint:P17661|reactome:R-HSA-390522|genbank_protein_gi:55749931(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	rogid:htjPzLKLLbRXxfKz9NUgMYMuIaY9606	intact-crc:4F924CF98DD6BE9C|rigid:o1mNHuif3Kh8zqCtdI6w+ur7Gco	false	sufficient binding region:1-705	sufficient binding region:333-470	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q58WW2	uniprotkb:Q8N3C7	intact:EBI-2559044|ensembl:ENSP00000311949|uniprotkb:Q8TB19|uniprotkb:Q8IXH3|uniprotkb:A2A295|uniprotkb:Q7L8I0|uniprotkb:B4DNB8	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:dcaf6_human(display_long)|uniprotkb:DCAF6(gene name)|psi-mi:DCAF6(display_short)|uniprotkb:IQWD1(gene name synonym)|uniprotkb:Nuclear receptor interaction protein(gene name synonym)|uniprotkb:IQ motif and WD repeat-containing protein 1(gene name synonym)|uniprotkb:Androgen receptor complex-associated protein(gene name synonym)|uniprotkb:MSTP055(orf name)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655602|imex:IM-16425-215	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143164(gene)|ensembl:ENST00000312263(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|refseq:NP_001017977.1|refseq:NP_001185885.1|refseq:NP_001185886.1|refseq:NP_060912.2|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q58WW2|rcsb pdb:3I7O|reactome:R-HSA-8951664|dip:DIP-44678N|genbank_protein_gi:27462067(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:1CtoPWPj6fdryvDlC46pXiUguDc9606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:94F35DE293C9B98D|rigid:bLErjcBpZC/UINw8TiIKgFtvhjA	false	sufficient binding region:688-860(IPR000048)	sufficient binding region:1-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3K9	uniprotkb:Q8N3C7	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655585|imex:IM-16425-214	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9|genbank_protein_gi:62241002(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:7F6BDD101CC254F3|rigid:JNgEc4X3wB9NY0hDBIRrai2nXkQ	false	sufficient binding region:47-4069	sufficient binding region:1-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60333	uniprotkb:Q8N3C7	intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|ensembl:ENSP00000366290|ensembl:ENSP00000502065|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655656|imex:IM-16425-218	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000054523(gene)|ensembl:ENST00000377086(transcript)|ensembl:ENST00000676179(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N|genbank_protein_gi:41393558(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:7BD036118184C4C4|rigid:q4w6QDnessuT6GSALC98aoG44+g	false	sufficient binding region:804-1816	sufficient binding region:1-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03001	uniprotkb:Q8N3C7	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655638|imex:IM-16425-217	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:1BAF9F2B66C849F0|rigid:LiMWdcTSBjXOkKzVlHpNfj1YQGU	false	sufficient binding region:4830-7570(IPR002048)	sufficient binding region:1-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3C7	uniprotkb:Q00872	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655690|imex:IM-16425-220	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:294A7E34E850D52F|rigid:ZdNXu6tYzhX5c22ms5OoCMhBqAw	false	sufficient binding region:1-705	sufficient binding region:620-1141(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q3KQU3	uniprotkb:Q8N3C7	intact:EBI-713229|uniprotkb:Q9HBQ2|uniprotkb:Q8N905|uniprotkb:Q9ULN3|uniprotkb:Q7L8J5|uniprotkb:Q8TAK0|intact:EBI-2511981|intact:EBI-1056140|ensembl:ENSP00000362244|uniprotkb:Q9NW29|uniprotkb:D3DPS4	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:ma7d1_human(display_long)|uniprotkb:MAP7D1(gene name)|psi-mi:MAP7D1(display_short)|uniprotkb:KIAA1187(gene name synonym)|uniprotkb:PARCC1(gene name synonym)|uniprotkb:RPRC1(gene name synonym)|uniprotkb:Proline/arginine-rich coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:Arginine/proline-rich coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:PP2464(orf name)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655673|imex:IM-16425-219	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273294.1|refseq:NP_001273295.1|ensembl:ENSG00000116871(gene)|ensembl:ENST00000373151(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR008604(E-MAP-115)|mint:Q3KQU3|refseq:NP_060537.3|genbank_protein_gi:78042576(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:AEal3/uaJsdRBdmijI8nuthBD9k9606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:14DE86CA931F1E13|rigid:Nxd0eixPqt3cDHaP6EDQaJeBc24	false	sufficient binding region:133-841	sufficient binding region:1-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86TG7	uniprotkb:Q8N3C7	intact:EBI-2858265|uniprotkb:Q9UPV1|uniprotkb:Q96A68	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:peg10_human(display_long)|uniprotkb:PEG10(gene name)|psi-mi:PEG10(display_short)|uniprotkb:EDR(gene name synonym)|uniprotkb:KIAA1051(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:MART2(gene name synonym)|uniprotkb:MEF3L1(gene name synonym)|uniprotkb:RGAG3(gene name synonym)|uniprotkb:Embryonal carcinoma differentiation-regulated protein(gene name synonym)|uniprotkb:Mammalian retrotransposon-derived protein 2(gene name synonym)|uniprotkb:Myelin expression factor 3-like protein 1(gene name synonym)|uniprotkb:Paternally expressed gene 10 protein(gene name synonym)|uniprotkb:Retrotransposon gag domain-containing protein 3(gene name synonym)|uniprotkb:Retrotransposon-derived gag-like polyprotein(gene name synonym)|uniprotkb:Ty3/Gypsy-like protein(gene name synonym)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655743|imex:IM-16425-223	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032549|interpro:IPR032567|refseq:NP_001035242.1|refseq:NP_001171890.1|refseq:NP_001171891.1|refseq:NP_055883.2|interpro:IPR021109|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|interpro:IPR043128|interpro:IPR043502|genbank_protein_gi:94421474(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wkCBsH9/PsFMwJFu/qOwZcn63D49606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:E5F2C65CDB231219|rigid:leTfjX6uJ4ItGwAN25LVdcz4YRI	false	sufficient binding region:7-708(IPR005162)	sufficient binding region:1-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3C7	uniprotkb:Q5VU43	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655726|imex:IM-16425-222	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|genbank_protein_gi:50658074(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	intact-crc:38132DBDFD73F0CD|rigid:dgXxUDbRgXERwMsJ4cKH4nLhdxs	false	sufficient binding region:1-705	sufficient binding region:148-2346	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11055	uniprotkb:Q8N3C7	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655709|imex:IM-16425-221	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:0B0D10A45D1ACE4D|rigid:9CFBNBGrf443S9pVteJbQf4pNzw	false	sufficient binding region:1423-1940	sufficient binding region:1-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3C7	uniprotkb:P21675	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655780|imex:IM-16425-225	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N|genbank_protein_gi:20357587(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	intact-crc:EE1099B04219EBE9|rigid:YfIbJrJGnCzWhSEGGu6p/ho9tr8	false	sufficient binding region:1-705	sufficient binding region:1233-1872	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3C7	uniprotkb:P18583	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	intact:EBI-1053513|uniprotkb:O14487|uniprotkb:O95981|uniprotkb:Q14120|uniprotkb:Q9H7B1|uniprotkb:Q9P070|uniprotkb:Q9P072|uniprotkb:Q9UKP9|uniprotkb:Q9UPY0|uniprotkb:D3DSF5|uniprotkb:D3DSF6|uniprotkb:E7ETE8|uniprotkb:E7EU67|uniprotkb:E7EVW3|uniprotkb:E9PFQ2|uniprotkb:Q6PKE0|intact:EBI-28988950|ensembl:ENSP00000348984	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:son_human(display_long)|uniprotkb:SON3(gene name synonym)|uniprotkb:Negative regulatory element-binding protein(gene name synonym)|uniprotkb:Protein DBP-5(gene name synonym)|uniprotkb:Bax antagonist selected in saccharomyces 1(gene name synonym)|uniprotkb:SON(gene name)|psi-mi:SON(display_short)|uniprotkb:C21orf50(gene name synonym)|uniprotkb:DBP5(gene name synonym)|uniprotkb:KIAA1019(gene name synonym)|uniprotkb:NREBP(gene name synonym)|uniprotkb:HSPC310(orf name)|uniprotkb:HSPC312(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655761|imex:IM-16425-224	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	refseq:NP_001278340.1|refseq:NP_001278341.1|refseq:NP_115571.2|refseq:NP_620305.2|ensembl:ENSG00000159140(gene)|ensembl:ENST00000356577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000467(D111/G-patch)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032922|interpro:IPR036322|mint:P18583|ensembl:ENST00000300278|ensembl:ENSP00000300278|ensembl:ENSP00000348984|ensembl:ENST00000381679|ensembl:ENSP00000371095|ensembl:ENST00000455528|ensembl:ENSP00000399783|dip:DIP-42289N|genbank_protein_gi:17046372(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	rogid:XHPM2q25vXRqEK7eQpWvJ6Uzc3U9606	intact-crc:B302A85400CA7B6A|rigid:pxNqDqH/Not04qIHNc3wVGpDtJg	false	sufficient binding region:1-705	sufficient binding region:1841-2426(IPR001159)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3C7	uniprotkb:P45378	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	intact:EBI-714264|uniprotkb:A8MQ76|uniprotkb:A8MSW1|uniprotkb:Q17RG9|uniprotkb:Q6FH29|uniprotkb:Q6N056|uniprotkb:Q12975|uniprotkb:Q12976|uniprotkb:Q12977|uniprotkb:Q12978|uniprotkb:Q86TH6|uniprotkb:B3KPX3|uniprotkb:B7WP64|uniprotkb:B7ZL26|uniprotkb:B7ZVV9|ensembl:ENSP00000380468|ensembl:ENSP00000500796	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:tnnt3_human(display_long)|uniprotkb:Fast skeletal muscle troponin T(gene name synonym)|uniprotkb:Beta-TnTF(gene name synonym)|uniprotkb:TNNT3(gene name)|psi-mi:TNNT3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655815|imex:IM-16425-227	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	refseq:NP_001036245.1|refseq:NP_001036246.1|refseq:NP_001036247.1|refseq:NP_006748.1|refseq:XP_006718353.1|refseq:XP_006718356.1|refseq:XP_006718363.1|refseq:NP_001284575.1|refseq:XP_016873695.1|refseq:XP_011518645.1|ensembl:ENSG00000130595(gene)|ensembl:ENSG00000288250(gene)|ensembl:ENST00000397301(transcript)|ensembl:ENST00000673082(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005861"(troponin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0030172"(troponin C binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:1903612"(positive regulation of calcium-dependent ATPase activity)|interpro:IPR001978(Troponin)|interpro:IPR027707|interpro:IPR027708|interpro:IPR038077|reactome:R-HSA-390522|genbank_protein_gi:112789540(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	rogid:aj91rEv9nNfxiOXvbn/fcCLyNjs9606	intact-crc:84E76C411A4933B3|rigid:7alTqfCLXuQoOg71L6RO7OnUpZM	false	sufficient binding region:1-705	sufficient binding region:93-269(IPR001978)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13805	uniprotkb:Q8N3C7	intact:EBI-726527|uniprotkb:O95472|uniprotkb:Q16061|uniprotkb:Q5U0E1|ensembl:ENSP00000467176	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:tnnt1_human(display_long)|uniprotkb:Slow skeletal muscle troponin T(gene name synonym)|uniprotkb:TNNT1(gene name)|psi-mi:TNNT1(display_short)|uniprotkb:TNT(gene name synonym)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655797|imex:IM-16425-226	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278703.1|refseq:NP_001119604.1|refseq:NP_001119605.1|refseq:NP_003274.3|refseq:XP_016882675.1|ensembl:ENSG00000105048(gene)|ensembl:ENST00000588981(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005861"(troponin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0031014"(troponin T binding)|go:"GO:0031444"(slow-twitch skeletal muscle fiber contraction)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045932"(negative regulation of muscle contraction)|interpro:IPR001978(Troponin)|interpro:IPR027707|interpro:IPR038077|mint:P13805|reactome:R-HSA-390522|genbank_protein_gi:21706666(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zYApSOt95yJcjJZHRMuHR9C5Kqw9606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:F4C74A88336D97AB|rigid:hdvQ8VmQKOP9Qco1OM9Hi3AAgIQ	false	sufficient binding region:136-278(IPR001978)	sufficient binding region:1-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8N3C7	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655850|imex:IM-16425-229	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:7F45BCF1F60E2CED|rigid:dhCteX7nYRJvzWIa8yKQTmQXFmw	false	sufficient binding region:31789-34350(IPR007110)	sufficient binding region:1-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3C7	uniprotkb:P09493	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	intact:EBI-351158|uniprotkb:P09494|uniprotkb:P10469|uniprotkb:Q86W64|uniprotkb:Q96IK2|uniprotkb:Q9Y427|uniprotkb:Q9UCY9|uniprotkb:Q6DV89|uniprotkb:Q6DV90|uniprotkb:Q9UCI1|uniprotkb:Q9UCI2|uniprotkb:B7Z5T7|uniprotkb:Q7Z6L8|intact:EBI-2558177|ensembl:ENSP00000385107|intact:EBI-11030042|uniprotkb:D9YZV2|uniprotkb:D9YZV3|uniprotkb:D9YZV8	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:tpm1_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655833|imex:IM-16425-228	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	refseq:NP_000357.3|refseq:NP_001018005.1|refseq:NP_001018006.1|refseq:NP_001018008.1|ensembl:ENSG00000140416(gene)|ensembl:ENST00000403994(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|mint:P09493|rcsb pdb:3MUD|rcsb pdb:5KHT|rcsb pdb:6UT2|rcsb pdb:6X5Z|reactome:R-HSA-390522|reactome:R-HSA-445355|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001288173.1|refseq:NP_001018007.1|refseq:NP_001018004.1|refseq:NP_001018020.1|refseq:XP_016878027.1|refseq:NP_001317273.1|refseq:NP_001317275.1|refseq:NP_001317280.1|genbank_protein_gi:63252897(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	rogid:rsKuZnKpbEqVOpYBz3PnoSBCSHs9606	intact-crc:C8F2156EA121D3E0|rigid:3FOSh1g/me2/YPEeZnrhOwFNslg	false	sufficient binding region:1-705	sufficient binding region:159-284..284	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q8N3C7	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655886|imex:IM-16425-231	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:C978475A881BDF53|rigid:HAvU14sebEeI37yKzTEjhBakk0k	false	sufficient binding region:55-442	sufficient binding region:1-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3C7	uniprotkb:Q8WZ42	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655868|imex:IM-16425-230	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:5ECA436C0045924E|rigid:dhCteX7nYRJvzWIa8yKQTmQXFmw	false	sufficient binding region:1-705	sufficient binding region:30598-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01484	uniprotkb:O75953	intact:EBI-941975|uniprotkb:Q01485|uniprotkb:Q08AC7|uniprotkb:Q08AC8|uniprotkb:Q7Z3L5|ensembl:ENSP00000349588	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	psi-mi:ank2_human(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655945|imex:IM-16425-234	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120965.1|refseq:NP_001139.3|refseq:NP_066187.2|dip:DIP-37425N|ensembl:ENSG00000145362(gene)|ensembl:ENST00000357077(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003283"(atrial septum development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745|mint:Q01484|rcsb pdb:4D8O|rcsb pdb:4RLV|rcsb pdb:4RLY|rcsb pdb:5Y4D|rcsb pdb:5Y4E|rcsb pdb:5Y4F|rcsb pdb:5YIR|rcsb pdb:5YIS|rcsb pdb:6KZJ|rcsb pdb:6M3Q|reactome:R-HSA-445095|reactome:R-HSA-6807878|genbank_protein_gi:52426734(identity)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wHoFDw3CIP2xOUZj9WzEMGm/z8k9606	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	intact-crc:B83829AB14FA7EF1|rigid:xVQwLJuJeTkU0OQw44Cj+/l40x8	false	sufficient binding region:3517-3957	sufficient binding region:118-339	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3K9	uniprotkb:P40189	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	intact:EBI-1030834|uniprotkb:Q9UQ41|ensembl:ENSP00000338799|ensembl:ENSP00000370698|ensembl:ENSP00000462158|uniprotkb:A0N0L4|uniprotkb:Q5FC04	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:il6rb_human(display_long)|uniprotkb:IL6ST(gene name)|psi-mi:IL6ST(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:CDw130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655920|imex:IM-16425-233	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9|genbank_protein_gi:62241002(identity)	ensembl:ENSG00000134352(gene)|ensembl:ENST00000336909(transcript)|ensembl:ENST00000381298(transcript)|ensembl:ENST00000502326(transcript)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004921"(interleukin-11 receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|refseq:NP_002175.2|refseq:NP_786943.1|rcsb pdb:1BJ8|rcsb pdb:1BQU|rcsb pdb:1I1R|rcsb pdb:1N2Q|rcsb pdb:1P9M|rcsb pdb:1PVH|rcsb pdb:3L5H|rcsb pdb:3L5I|rcsb pdb:3L5J|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-6788467|reactome:R-HSA-8984722|reactome:R-HSA-9020956|go:"GO:0034097"(response to cytokine)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045509"(interleukin-27 receptor activity)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1901731"(positive regulation of platelet aggregation)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:P40189|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019970"(interleukin-11 binding)|go:"GO:0030425"(dendrite)|refseq:NP_001177910.1|dip:DIP-95N|genbank_protein_gi:117606495(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	rogid:0DhlsbEh3ZiKomQFf+5mjd6hUOM9606	intact-crc:775D54FCBF6041D7|rigid:Wzzrwcn/qpTdzMexfNWZ5+/vR54	false	sufficient binding region:1-1000	sufficient binding region:7-918	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3K9	uniprotkb:Q8N3K9	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655903|imex:IM-16425-232	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9|genbank_protein_gi:62241002(identity)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9|genbank_protein_gi:62241002(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	intact-crc:F9E3E4B09B328093|rigid:TfeOF+wT/ozrUxPYWPkuZdp7cH0	false	sufficient binding region:1-1000	sufficient binding region:138-4069	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75953	uniprotkb:Q9UK39	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	intact:EBI-5655962|uniprotkb:Q9HD95|uniprotkb:Q14D51|uniprotkb:Q9HD94|uniprotkb:Q9HD93|uniprotkb:D3DNY5|ensembl:ENSP00000280614	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:noct_human(display_long)|uniprotkb:NOCT(gene name)|psi-mi:NOCT(display_short)|uniprotkb:CCR4(gene name synonym)|uniprotkb:CCRN4L(gene name synonym)|uniprotkb:Carbon catabolite repression 4-like protein(gene name synonym)|uniprotkb:NOC(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655971|imex:IM-16425-235	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	refseq:NP_036250.2|ensembl:ENSG00000151014(gene)|ensembl:ENST00000280614(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019178"(NADP phosphatase activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033962"(P-body assembly)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0102757"(NADPH phosphatase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR034965|interpro:IPR036691|interpro:IPR040109|rcsb pdb:6BT1|rcsb pdb:6BT2|rcsb pdb:6MAL|rcsb pdb:6NF0|reactome:R-HSA-1368108|go:"GO:0042752"(regulation of circadian rhythm)|genbank_protein_gi:31083027(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	rogid:ceMP1CwURM8p383yJ/186kFO/9U9606	intact-crc:031EF3B6F811DD66|rigid:zK25/7nhiuEsehdADyt2BhfcVfY	false	sufficient binding region:118-339	sufficient binding region:94-431(IPR005135)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VST9	uniprotkb:O75953	intact:EBI-941850|uniprotkb:Q2A664|uniprotkb:Q5T7G8|uniprotkb:Q5T7G9|uniprotkb:Q5VSU2|uniprotkb:Q86YC7|uniprotkb:Q8NHN0|uniprotkb:Q8NHN1|uniprotkb:Q8NHN2|uniprotkb:Q8NHN3|uniprotkb:Q8NHN4|uniprotkb:Q8NHN5|uniprotkb:Q8NHN6|uniprotkb:Q8NHN7|uniprotkb:Q8NHN8|uniprotkb:Q8NHN9|uniprotkb:Q96AA2|uniprotkb:Q9HCD3|uniprotkb:Q9HCL6|ensembl:ENSP00000409493	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	psi-mi:obscn_human(display_long)|uniprotkb:OBSCN(gene name)|psi-mi:OBSCN(display_short)|uniprotkb:KIAA1639(gene name synonym)|uniprotkb:Obscurin-myosin light chain kinase(gene name synonym)|uniprotkb:Obscurin-RhoGEF(gene name synonym)|uniprotkb:KIAA1556(gene name synonym)	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656025|imex:IM-16425-238	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000284548|ensembl:ENSP00000284548|ensembl:ENSP00000409493|ensembl:ENST00000636476|ensembl:ENSP00000489816|ensembl:ENST00000662438|ensembl:ENSP00000499633|refseq:NP_001092093.2|refseq:NP_443075.3|dip:DIP-35727N|ensembl:ENSG00000154358(gene)|ensembl:ENST00000422127(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0042383"(sarcolemma)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020682|interpro:IPR035526|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1V1C|rcsb pdb:2CR6|rcsb pdb:2DKU|rcsb pdb:2DM7|rcsb pdb:2E7B|rcsb pdb:2EDF|rcsb pdb:2EDH|rcsb pdb:2EDL|rcsb pdb:2EDQ|rcsb pdb:2EDR|rcsb pdb:2EDT|rcsb pdb:2EDW|rcsb pdb:2ENY|rcsb pdb:2EO1|rcsb pdb:2GQH|rcsb pdb:2MWC|rcsb pdb:2N56|rcsb pdb:2YZ8|rcsb pdb:4C4K|rcsb pdb:4RSV|rcsb pdb:4UOW|rcsb pdb:5TZM|rcsb pdb:6MG9|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013406|genbank_protein_gi:22046663(identity)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:pUzPNEELWyEtZa4+ra9kGoGMntc9606	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	intact-crc:EA786BE30124C5EC|rigid:PhI2wkLCYMpUZnk/l9/izFCRjQE	false	sufficient binding region:4224-7968	sufficient binding region:118-339	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75953	uniprotkb:Q00872	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656006|imex:IM-16425-237	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:52B31436B173663C|rigid:lvUKZZB98wEtXTtMGoiztHHb16w	false	sufficient binding region:118-339	sufficient binding region:349-1141(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y605	uniprotkb:O75953	intact:EBI-995714|uniprotkb:B3KVT2|ensembl:ENSP00000318352|ensembl:ENSP00000372024|ensembl:ENSP00000422065|uniprotkb:D3DVT3	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	psi-mi:mofa1_human(display_long)|uniprotkb:PGR1(gene name synonym)|uniprotkb:Protein PGR1(gene name synonym)|uniprotkb:Protein associated with MRG of 14 kDa(gene name synonym)|uniprotkb:MRFAP1(gene name)|psi-mi:MRFAP1(display_short)|uniprotkb:PAM14(gene name synonym)	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5655989|imex:IM-16425-236	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_150638.1|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR029254|mint:Q9Y605|ensembl:ENSG00000179010(gene)|ensembl:ENST00000320912(transcript)|ensembl:ENST00000382581(transcript)|ensembl:ENST00000507420(transcript)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001258982.1|genbank_protein_gi:50505696(identity)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:qsRG2MjlSzgcyuUj0/45kBNrfw89606	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	intact-crc:509A2B9A96805299|rigid:zOwfTzywR0LSGnLEpyidDJMfvLY	false	sufficient binding region:50-127..127	sufficient binding region:118-339	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75953	uniprotkb:Q15796	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	intact:EBI-1040141|ensembl:ENSP00000262160|ensembl:ENSP00000384449	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:smad2_human(display_long)|uniprotkb:SMAD2(gene name)|psi-mi:SMAD2(display_short)|uniprotkb:MADH2(gene name synonym)|uniprotkb:MADR2(gene name synonym)|uniprotkb:Mad-related protein 2(gene name synonym)|uniprotkb:SMAD family member 2(gene name synonym)|uniprotkb:JV18-1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656042|imex:IM-16425-239	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	refseq:NP_001003652.1|refseq:NP_005892.1|refseq:XP_006722514.1|ensembl:ENSG00000175387(gene)|ensembl:ENST00000262160(transcript)|ensembl:ENST00000402690(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001706"(endoderm formation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009749"(response to glucose)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035265"(organ growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051098"(regulation of binding)|go:"GO:0060039"(pericardium development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0062009"(secondary palate development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15796|rcsb pdb:1DEV|rcsb pdb:1KHX|rcsb pdb:1U7V|rcsb pdb:2LB3|rcsb pdb:5XOD|rcsb pdb:5ZOJ|rcsb pdb:6M64|rcsb pdb:6ZVQ|rcsb pdb:7CO1|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-9615017|reactome:R-HSA-9617828|refseq:XP_016881234.1|refseq:XP_016881235.1|refseq:XP_005258316.1|dip:DIP-29716N|genbank_protein_gi:118572581(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	rogid:B+vgtzdbCnUXt22sbXtPwuudTNs9606	intact-crc:A4D48C108FC8F6DD|rigid:QbPaWyM2mp5MOAJrwd4QxSOk7oU	false	sufficient binding region:118-339	sufficient binding region:232-467(IPR001132)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75953	uniprotkb:Q8WZ42	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656094|imex:IM-16425-242	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:99A8CC56260FF022|rigid:k49fvi5XwA9rd0dPwsQosxEA8Rw	false	sufficient binding region:118-339	sufficient binding region:33332-34350(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21675	uniprotkb:O75953	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656077|imex:IM-16425-241	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N|genbank_protein_gi:20357587(identity)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	intact-crc:10473CE851E3B0AB|rigid:KWnxoJaw/MwOhUfwapTIbUg9/hQ	false	sufficient binding region:1047-1872	sufficient binding region:118-339	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75953	uniprotkb:P84022	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656060|imex:IM-16425-240	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828|genbank_protein_gi:52352808(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606	intact-crc:08341BE046B8F5ED|rigid:fo9JaWN/lEf3ul76fM7WxTXOYeY	false	sufficient binding region:118-339	sufficient binding region:252-425	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75953	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656130|imex:IM-16425-244	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	intact-crc:3D517AD74B8010DE|rigid:k49fvi5XwA9rd0dPwsQosxEA8Rw	false	sufficient binding region:12988-34350(IPR003961)	sufficient binding region:118-339	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75953	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656112|imex:IM-16425-243	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	intact-crc:F83C05074E42C43B|rigid:k49fvi5XwA9rd0dPwsQosxEA8Rw	false	sufficient binding region:2379-34350(IPR003599)	sufficient binding region:118-339	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75190	uniprotkb:Q9ULH1	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656165|imex:IM-16425-246	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|genbank_protein_gi:46094080(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	intact-crc:A2C3913CFAC9D827|rigid:zQQm5Gmys9EUD8yOMwnSCAAW8QI	false	sufficient binding region:79-287	sufficient binding region:1071-1129..1129	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15327	uniprotkb:O75190	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656148|imex:IM-16425-245	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:FD66DB835CB584D7|rigid:6vZ58raD/vWwi+/PnGPi3xAIKe8	false	sufficient binding region:1-319	sufficient binding region:79-287	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P58340	uniprotkb:O75190	intact:EBI-721328|intact:EBI-767466|uniprotkb:E9PEU9|uniprotkb:Q2TLE5|uniprotkb:Q8N8F8|uniprotkb:Q96MH1|uniprotkb:Q2TLE3|ensembl:ENSP00000348157	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:mlf1_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 1(gene name synonym)|uniprotkb:MLF1(gene name)|psi-mi:MLF1(display_short)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656205|imex:IM-16425-248	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071888.1|refseq:NP_001182361.1|refseq:NP_001182362.1|refseq:NP_001182363.1|refseq:XP_011511154.1|refseq:NP_001123628.1|refseq:NP_001123629.1|ensembl:ENSP00000348157|ensembl:ENST00000359117|ensembl:ENSP00000352025|ensembl:ENST00000392822|ensembl:ENSP00000376568|ensembl:ENST00000469452|ensembl:ENSP00000418595|ensembl:ENST00000471745|ensembl:ENSP00000420134|ensembl:ENST00000477042|ensembl:ENSP00000419637|ensembl:ENST00000478894|ensembl:ENSP00000417777|ensembl:ENST00000482628|ensembl:ENSP00000417141|ensembl:ENST00000484955|ensembl:ENSP00000417835|ensembl:ENST00000618075|ensembl:ENSP00000484169|ensembl:ENST00000651874|ensembl:ENSP00000498363|refseq:XP_011511155.1|refseq:XP_005247537.1|ensembl:ENSG00000178053(gene)|ensembl:ENST00000355893(transcript)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR019376|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6Y8E|genbank_protein_gi:33636694(identity)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:czY64xaocTjgRFAtZU19jvH4MIo9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:119DB6E4F99D2605|rigid:JT/SLkSfPjcmjYzpskTnK6lXDqU	false	sufficient binding region:12-268	sufficient binding region:79-287	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75190	uniprotkb:O75155	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656188|imex:IM-16425-247	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712(gene)|ensembl:ENST00000456430(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155|genbank_protein_gi:112420976(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606	intact-crc:4ECBAA7C5B731886|rigid:+5yhe4yIxDVxHreqU8sNozEcI+Q	false	sufficient binding region:79-287	sufficient binding region:149-1236	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75190	uniprotkb:Q15773	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656222|imex:IM-16425-249	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773|genbank_protein_gi:4885486(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	intact-crc:E4E2185F04F5104B|rigid:E8NyzVIbIHY7w4rq8WCmzGdxzPs	false	sufficient binding region:79-287	sufficient binding region:90-248	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75190	uniprotkb:Q9UKD2	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	intact:EBI-1046493|ensembl:ENSP00000364320|uniprotkb:Q9BPV9|uniprotkb:Q5TG55|uniprotkb:Q96SS6|uniprotkb:B3KNB3	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:mrt4_human(display_long)|uniprotkb:MRTO4(gene name)|psi-mi:MRTO4(display_short)|uniprotkb:C1orf33(gene name synonym)|uniprotkb:MRT4(gene name synonym)|uniprotkb:Ribosome assembly factor MRTO4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656239|imex:IM-16425-250	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	ensembl:ENSG00000053372(gene)|ensembl:ENST00000330263(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:Q9UKD2|interpro:IPR033867|refseq:NP_057267.2|genbank_protein_gi:118572609(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	rogid:LpvX3By1Cp6MxlAx3d5qoDM3FNY9606	intact-crc:6FE332CE70DC1C69|rigid:820VpQj/GApgp2x7qgtI5SjiZ50	false	sufficient binding region:79-287	sufficient binding region:116-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75190	uniprotkb:Q00872	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656274|imex:IM-16425-252	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:1912F0CD5A0A63DC|rigid:O89qqhbLIP7uk8B9O9UYM1Y0SuU	false	sufficient binding region:79-287	sufficient binding region:1121-1141..1141(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75190	uniprotkb:Q00872	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656256|imex:IM-16425-251	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:6E0EA1BA10AECD26|rigid:O89qqhbLIP7uk8B9O9UYM1Y0SuU	false	sufficient binding region:79-287	sufficient binding region:103-1141(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52179	uniprotkb:O75190	intact:EBI-5353249|uniprotkb:Q14BD6|uniprotkb:Q6H969|uniprotkb:Q6ZUU0|ensembl:ENSP00000348821	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:myom1_human(display_long)|uniprotkb:MYOM1(gene name)|psi-mi:MYOM1(display_short)|uniprotkb:190 kDa connectin-associated protein(gene name synonym)|uniprotkb:190 kDa titin-associated protein(gene name synonym)|uniprotkb:Myomesin family member 1(gene name synonym)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656292|imex:IM-16425-253	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59649N|refseq:NP_003794.3|refseq:NP_062830.1|ensembl:ENSG00000101605(gene)|ensembl:ENST00000356443(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P52179|rcsb pdb:2R15|rcsb pdb:2Y23|rcsb pdb:2Y25|rcsb pdb:3RBS|rcsb pdb:5FM4|rcsb pdb:5FM5|rcsb pdb:5FM8|rcsb pdb:6T3O|genbank_protein_gi:46249363(identity)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5lfd5o+54eyer647zxvU0LX1wpM9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:6A0F9A18AB1D77B0|rigid:Bax6jMt8lHMr4bj+DrQ+cx6r9VI	false	sufficient binding region:1241-1685(IPR003599)	sufficient binding region:79-287	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36871	uniprotkb:O75190	intact:EBI-2861475|uniprotkb:Q5BKZ9|uniprotkb:Q96J40|uniprotkb:Q9NTY4|uniprotkb:Q6NW22|uniprotkb:Q86U74|uniprotkb:Q16105|uniprotkb:B2R5N9|uniprotkb:B4DPV0|uniprotkb:Q16106|ensembl:ENSP00000360125	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:pgm1_human(display_long)|uniprotkb:PGM1(gene name)|psi-mi:PGM1(display_short)|uniprotkb:Glucose phosphomutase 1(gene name synonym)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656311|imex:IM-16425-254	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166289.1|refseq:NP_001166290.1|refseq:NP_002624.2|dip:DIP-60903N|reactome:R-HSA-5609974|reactome:R-HSA-6798695|reactome:R-HSA-3322077|ensembl:ENSG00000079739(gene)|ensembl:ENST00000371084(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900|rcsb pdb:5EPC|rcsb pdb:5F9C|rcsb pdb:5HSH|rcsb pdb:5JN5|rcsb pdb:5TR2|rcsb pdb:5VBI|rcsb pdb:5VEC|rcsb pdb:5VG7|rcsb pdb:5VIN|rcsb pdb:6SNO|rcsb pdb:6SNP|rcsb pdb:6SNQ|rcsb pdb:6UIQ|rcsb pdb:6UO6|genbank_protein_gi:21361620(identity)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:K9cGu3lfysJ4hVP0S0jewZsZjSE9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:CEE78D6AEC9D2F42|rigid:lRmk+CcLZz9E6Tt0EC8uIR3ytcA	false	sufficient binding region:453-562(IPR005843)	sufficient binding region:79-287	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75563	uniprotkb:O75190	intact:EBI-2483161|ensembl:ENSP00000005587|uniprotkb:Q53GP6|uniprotkb:Q75MK6|uniprotkb:Q75MZ4|uniprotkb:Q9UBZ3|uniprotkb:Q9UED8|uniprotkb:A4D173	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:skap2_human(display_long)|uniprotkb:SKAP2(gene name)|psi-mi:SKAP2(display_short)|uniprotkb:PRAP(gene name synonym)|uniprotkb:RA70(gene name synonym)|uniprotkb:SAPS(gene name synonym)|uniprotkb:SCAP2(gene name synonym)|uniprotkb:SKAP55R(gene name synonym)|uniprotkb:Src family-associated phosphoprotein 2(gene name synonym)|uniprotkb:Src kinase-associated phosphoprotein 55-related protein(gene name synonym)|uniprotkb:SKAP55 homolog(gene name synonym)|uniprotkb:Src-associated adapter protein with PH and SH3 domains(gene name synonym)|uniprotkb:Pyk2/RAFTK-associated protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 70(gene name synonym)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656329|imex:IM-16425-255	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000005020(gene)|ensembl:ENST00000345317(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|interpro:IPR037781|rcsb pdb:3OMH|reactome:R-HSA-391160|refseq:NP_001290397.1|refseq:NP_003921.2|refseq:XP_016868260.1|genbank_protein_gi:38202227(identity)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/DicuSIa8/M32bXSYfuzrx8gHK89606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:1E963482E817B83B|rigid:pgP9a6/iAsQeOwn3s8EW+7/+se4	false	sufficient binding region:199-359..359	sufficient binding region:79-287	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7KZ85	uniprotkb:O75190	intact:EBI-2515547|ensembl:ENSP00000319104|ensembl:ENSP00000338143|uniprotkb:Q96AH3|uniprotkb:Q7KYW9|uniprotkb:Q6GMQ4|uniprotkb:Q8N526|uniprotkb:Q15737|uniprotkb:Q9BTI2|uniprotkb:Q92775|uniprotkb:Q9BTH9|uniprotkb:Q7LDK4|uniprotkb:A7E2B4	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:spt6h_human(display_long)|uniprotkb:SUPT6H(gene name)|psi-mi:SUPT6H(display_short)|uniprotkb:KIAA0162(gene name synonym)|uniprotkb:SPT6H(gene name synonym)|uniprotkb:Tat-cotransactivator 2 protein(gene name synonym)|uniprotkb:Histone chaperone suppressor of Ty6(gene name synonym)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656346|imex:IM-16425-256	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045191"(regulation of isotype switching)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051028"(mRNA transport)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR000980(SH2 motif)|interpro:IPR003029(S1, RNA binding)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR022967|interpro:IPR023319|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR041692|interpro:IPR042066|mint:Q7KZ85|rcsb pdb:6GME|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|interpro:IPR023323|ensembl:ENSG00000109111(gene)|ensembl:ENST00000314616(transcript)|ensembl:ENST00000347486(transcript)|go:"GO:0001825"(blastocyst formation)|refseq:XP_016880467.1|refseq:XP_016880468.1|refseq:XP_016880469.1|refseq:NP_003161.2|refseq:NP_001307684.1|dip:DIP-42615N|genbank_protein_gi:75677341(identity)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:G1HKe2xEnti5tcZvbH4uqLOwKNg9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:C6A8B2B9FFFFC353|rigid:BL4wiyrMNS9+wNDMAZXyRsArb7s	false	sufficient binding region:1035-1726	sufficient binding region:79-287	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75190	uniprotkb:Q8WZ42	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656363|imex:IM-16425-257	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:3273BCDB6094D656|rigid:E7IrKeJsTh+qhDmL1SkCKThYmCo	false	sufficient binding region:79-287	sufficient binding region:30684-34350(IPR00396)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CW5	uniprotkb:O75190	intact:EBI-1046278|ensembl:ENSP00000261965|uniprotkb:O43631|uniprotkb:O60852|uniprotkb:O60853|uniprotkb:Q7Z4K1|uniprotkb:Q96I79|uniprotkb:Q5T8L2	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:gcp3_human(display_long)|uniprotkb:Spindle pole body protein Spc98 homolog(gene name synonym)|uniprotkb:TUBGCP3(gene name)|psi-mi:TUBGCP3(display_short)|uniprotkb:GCP3(gene name synonym)|uniprotkb:Gamma-ring complex protein 104 kDa(gene name synonym)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656400|imex:IM-16425-259	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007338"(single fertilization)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q96CW5|rcsb pdb:6V6B|go:"GO:0000930"(gamma-tubulin complex)|rcsb pdb:6V6S|rcsb pdb:6X0U|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|ensembl:ENSG00000126216(gene)|ensembl:ENST00000261965(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000923"(equatorial microtubule organizing center)|refseq:NP_006313.1|refseq:NP_001273207.1|refseq:NP_001273208.1|refseq:NP_001273206.1|genbank_protein_gi:34222302(identity)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:xt+Ngo2s/4djh2PnyMEaxgDyLrs9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:6974905EAE7A1137|rigid:/b+WW87+idLD3gmjCbjoNizcnuQ	false	sufficient binding region:719-907..907(IPR007259)	sufficient binding region:79-287	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75190	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656382|imex:IM-16425-258	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:2F923381F50E5556|rigid:E7IrKeJsTh+qhDmL1SkCKThYmCo	false	sufficient binding region:29427-34350(IPR003961)	sufficient binding region:79-287	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94817	uniprotkb:Q9BZ29	intact:EBI-746742|uniprotkb:Q6PJV2|ensembl:ENSP00000425107	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	psi-mi:atg12_human(display_long)|uniprotkb:Autophagy-related protein 12(gene name synonym)|uniprotkb:ATG12(gene name)|psi-mi:ATG12(display_short)|uniprotkb:APG12(gene name synonym)|uniprotkb:APG12L(gene name synonym)	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656418|imex:IM-16425-260	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|reactome:R-HSA-936440|refseq:NP_004698.3|ensembl:ENSG00000145782(gene)|ensembl:ENST00000509910(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|refseq:NP_001264712.1|dip:DIP-46466N|genbank_protein_gi:290560745(identity)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|genbank_protein_gi:24308028(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V+K93xoWUNtOTJk4k03IP+Q+HfA9606	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	intact-crc:13D0366EDC5638BE|rigid:KQzC1+tjwJU6FMUT3GDs/lazsMg	false	sufficient binding region:1-140	sufficient binding region:1-887	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZ29	uniprotkb:P49759	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	intact:EBI-473775|uniprotkb:Q8N5V8|uniprotkb:Q0P694|intact:EBI-2622912|uniprotkb:B4DFW7|ensembl:ENSP00000326830	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:clk1_human(display_long)|uniprotkb:CDC-like kinase 1(gene name synonym)|uniprotkb:CLK1(gene name)|psi-mi:CLK1(display_short)|uniprotkb:CLK(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656435|imex:IM-16425-261	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|genbank_protein_gi:24308028(identity)	refseq:NP_004062.2|refseq:NP_001155879.1|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49759|rcsb pdb:1Z57|rcsb pdb:2VAG|rcsb pdb:5J1V|rcsb pdb:5J1W|rcsb pdb:5X8I|rcsb pdb:6FT8|rcsb pdb:6FT9|rcsb pdb:6FYO|rcsb pdb:6G33|rcsb pdb:6I5H|rcsb pdb:6I5I|rcsb pdb:6I5K|rcsb pdb:6I5L|rcsb pdb:6KHD|rcsb pdb:6Q8K|rcsb pdb:6Q8P|rcsb pdb:6QTY|rcsb pdb:6R3D|rcsb pdb:6R6E|rcsb pdb:6R6X|rcsb pdb:6R8J|rcsb pdb:6RAA|rcsb pdb:6TW2|rcsb pdb:6YTA|rcsb pdb:6YTD|rcsb pdb:6YTE|rcsb pdb:6YTG|rcsb pdb:6YTI|rcsb pdb:6Z4Z|rcsb pdb:6Z50|rcsb pdb:6ZLN|rcsb pdb:7AK3|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensembl:ENSG00000013441(gene)|ensembl:ENST00000321356(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|genbank_protein_gi:67551262(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	rogid:HUyYLfLTfZHyTdtTNdbR/HPBloM9606	intact-crc:99068F8280CA1FF2|rigid:Vh+zCT8ll91GyRqCr+qMyYTCB2s	false	sufficient binding region:1-887	sufficient binding region:47-484	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13642	uniprotkb:Q9BZ29	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656452|imex:IM-16425-262	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|genbank_protein_gi:24308028(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	intact-crc:E3F7780603FD6DB8|rigid:0W2madO2AAvlMJz5wdQfmCsptwA	false	sufficient binding region:1-323	sufficient binding region:1-887	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZ29	uniprotkb:Q9UBF9	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	intact:EBI-296701|uniprotkb:A0A4R6|uniprotkb:B4DT79	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:myoti_human(display_long)|uniprotkb:MYOT(gene name)|psi-mi:MYOT(display_short)|uniprotkb:TTID(gene name synonym)|uniprotkb:Titin immunoglobulin domain protein(gene name synonym)|uniprotkb:Myofibrillar titin-like Ig domains protein(gene name synonym)|uniprotkb:57 kDa cytoskeletal protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656469|imex:IM-16425-263	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|genbank_protein_gi:24308028(identity)	go:"GO:0030424"(axon)|go:"GO:0042383"(sarcolemma)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050808"(synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0030018"(Z disc)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001129412.1|refseq:NP_006781.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|rcsb pdb:2KDG|rcsb pdb:2KKQ|refseq:NP_001287840.1|interpro:IPR036179|genbank_protein_gi:5803105(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	rogid:y7p/HY416pf0hNjpo0B5cRolBAk9606	intact-crc:17486CB9B01E77AE|rigid:hel8RwdAfCoee7DIbo8hCJwOQLA	false	sufficient binding region:1-887	sufficient binding region:1-498..498	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZ29	uniprotkb:P20929	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656486|imex:IM-16425-264	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|genbank_protein_gi:24308028(identity)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:245E3D57E818AFDE|rigid:oTvGvOw1arOgSezx2Onf+qU1Ovo	false	sufficient binding region:1-887	sufficient binding region:5323-6669(IPR000900)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZ29	uniprotkb:Q14511	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	intact:EBI-2108053|uniprotkb:Q5T9R4|uniprotkb:A8K9G7|uniprotkb:G5E9Y9|uniprotkb:A8MSJ9|uniprotkb:Q5XKI0|intact:EBI-28980032|ensembl:ENSP00000368759	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:casl_human(display_long)|uniprotkb:NEDD9(gene name)|psi-mi:NEDD9(display_short)|uniprotkb:CASL(gene name synonym)|uniprotkb:CASS2(gene name synonym)|uniprotkb:CRK-associated substrate-related protein(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 9(gene name synonym)|uniprotkb:Cas scaffolding protein family member 2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-12(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656504|imex:IM-16425-265	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|genbank_protein_gi:24308028(identity)	refseq:NP_006394.1|refseq:NP_892011.2|refseq:NP_001135865.1|ensembl:ENST00000379433|ensembl:ENSP00000368745|ensembl:ENSP00000368759|ensembl:ENST00000504387|ensembl:ENSP00000422871|refseq:NP_001257962.1|interpro:IPR035746|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:Q14511|rcsb pdb:2L81|rcsb pdb:5X3S|ensembl:ENSG00000111859(gene)|ensembl:ENST00000379446(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0040008"(regulation of growth)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051301"(cell division)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|genbank_protein_gi:33667045(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	rogid:3PsYJXDgAihLYOOwKMBtDhQZQkU9606	intact-crc:1E1F1529B77D9091|rigid:TYLmX4GJ+5OdzcPrkV+cwt4ep5Q	false	sufficient binding region:1-887	sufficient binding region:819-834..834	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H1E3	uniprotkb:Q9BZ29	intact:EBI-1390111|uniprotkb:Q5PXE7|uniprotkb:Q9H1D6|uniprotkb:Q9H723|uniprotkb:Q54AC0|ensembl:ENSP00000356110	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	psi-mi:nucks_human(display_long)|uniprotkb:P1(gene name synonym)|uniprotkb:NUCKS1(gene name)|psi-mi:NUCKS1(display_short)|uniprotkb:NUCKS(gene name synonym)|uniprotkb:JC7(orf name)	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656521|imex:IM-16425-266	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_073568.2|mint:Q9H1E3|interpro:IPR026633|ensembl:ENSG00000069275(gene)|ensembl:ENST00000367142(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019046"(release from viral latency)|go:"GO:0031297"(replication fork processing)|go:"GO:0035822"(gene conversion)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0060382"(regulation of DNA strand elongation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990968"(modulation by host of RNA binding by virus)|go:"GO:1990969"(modulation by host of viral RNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|genbank_protein_gi:181336713(identity)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|genbank_protein_gi:24308028(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KYG9QwIUKWdRofCU7BAlbRdZe+Y9606	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	intact-crc:15E47D6C2F8DE6BA|rigid:pHQ1obHeBQReFfzg5eQ9Hcy9bUc	false	sufficient binding region:1-243	sufficient binding region:1-887	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZ29	uniprotkb:Q16537	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656538|imex:IM-16425-267	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|genbank_protein_gi:24308028(identity)	ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1|genbank_protein_gi:31083295(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606	intact-crc:B015CEDF865993E5|rigid:cET3lNBfN4x0LvGTk8U30RqNcdE	false	sufficient binding region:1-887	sufficient binding region:233-467..467(IPR002554)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZ29	uniprotkb:O95295	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656556|imex:IM-16425-268	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|genbank_protein_gi:24308028(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:2ED9F5D28B706B4F|rigid:782KLBCzB0Njkfom87Ti4qBSoBw	false	sufficient binding region:1-887	sufficient binding region:38-136..136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21675	uniprotkb:Q9BZ29	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656573|imex:IM-16425-269	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N|genbank_protein_gi:20357587(identity)	refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|genbank_protein_gi:24308028(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	intact-crc:54EC42CAC61D70CD|rigid:kWBdRoSYpPx75KBJ0saB+cMyipE	false	sufficient binding region:1047-1872	sufficient binding region:1-887	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q92667	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656607|imex:IM-16425-271	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231|genbank_protein_gi:109637793(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606	intact-crc:91D43C1818B31667|rigid:CHiRL9Ojo6sca70VDIaOkOCKVbM	false	sufficient binding region:1145-2026	sufficient binding region:544-903(IPR004088)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35609	uniprotkb:O75923	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656590|imex:IM-16425-270	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:7DE9E8DE6064D8F5|rigid:TZPLcsNwCB5w09wTinI05b0VzAA	false	sufficient binding region:438-894	sufficient binding region:851-1200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8TCU4	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-308651|uniprotkb:Q53S05|uniprotkb:Q580Q8|uniprotkb:Q86VP9|uniprotkb:Q9Y4G4|ensembl:ENSP00000482968|uniprotkb:A0A087WZY3	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:alms1_human(display_long)|uniprotkb:ALMS1(gene name)|psi-mi:ALMS1(display_short)|uniprotkb:KIAA0328(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656625|imex:IM-16425-272	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	ensembl:ENSG00000116127(gene)|ensembl:ENST00000613296(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0008017"(microtubule binding)|go:"GO:0016197"(endosomal transport)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR028781|interpro:IPR029299|interpro:IPR040972|mint:Q8TCU4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055935.4|genbank_protein_gi:110349785(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:e91Hcs947kpQHPVhWAJRtYegdPg9606	intact-crc:DEFF8187243E9066|rigid:oxv5dWTF3geQeVZtqpBK2TIvTt8	false	sufficient binding region:2-485	sufficient binding region:3905-4168	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q15327	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-5653378|uniprotkb:Q96LE7|ensembl:ENSP00000360762	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:ankr1_human(display_long)|uniprotkb:C193(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:Cardiac ankyrin repeat protein(gene name synonym)|uniprotkb:Cytokine-inducible gene C-193 protein(gene name synonym)|uniprotkb:Cytokine-inducible nuclear protein(gene name synonym)|uniprotkb:HA1A2(gene name synonym)|uniprotkb:ANKRD1(gene name)|psi-mi:ANKRD1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656642|imex:IM-16425-273	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_055206.2|ensembl:ENSG00000148677(gene)|ensembl:ENST00000371697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1989781|genbank_protein_gi:38327521(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:UQq7pp3hORsCvEVEvGXE7gq+4mk9606	intact-crc:71A3FF3B2F2BA98A|rigid:V1jgskR/cfx8o4dV7ljZppKV28Y	false	sufficient binding region:2-485	sufficient binding region:1-319	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8N3K9	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656676|imex:IM-16425-275	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9|genbank_protein_gi:62241002(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	intact-crc:7795A14A7F6EE57C|rigid:zcJ6wZwV5qZBS/Lil/11w0eDZ8Y	false	sufficient binding region:2-485	sufficient binding region:125-4069	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q9UKG1	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656659|imex:IM-16425-274	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N|genbank_protein_gi:34192027(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:24C060FA8A2ED060|rigid:gf7I8HDoWGpDVVnH3OUaPLKc/9c	false	sufficient binding region:851-1200	sufficient binding region:1-709..709	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:P12111	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-2465936|ensembl:ENSP00000295550|uniprotkb:Q53QF4|uniprotkb:Q53QF6|uniprotkb:Q16501|uniprotkb:B4E3U5|uniprotkb:E9PGQ9|uniprotkb:A8MT30|uniprotkb:B7ZMJ7|uniprotkb:E9PFQ6	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:co6a3_human(display_long)|uniprotkb:COL6A3(gene name)|psi-mi:COL6A3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656711|imex:IM-16425-277	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042383"(sarcolemma)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|go:"GO:0005615"(extracellular space)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR020901|interpro:IPR036116|interpro:IPR036465|interpro:IPR036880|interpro:IPR041900|rcsb pdb:1KNT|rcsb pdb:1KTH|rcsb pdb:1KUN|rcsb pdb:2KNT|rcsb pdb:6SNK|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8948216|mint:P12111|ensembl:ENSG00000163359(gene)|ensembl:ENST00000295550(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005589"(collagen type VI trimer)|refseq:NP_476506.3|refseq:NP_004360.2|refseq:NP_476508.2|refseq:NP_476505.3|refseq:NP_476507.3|refseq:XP_016858792.1|genbank_protein_gi:55743105(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:7xGWLmEvMdbEeoy4MT+iheiQkB09606	intact-crc:6E516443392157E2|rigid:Aw7duwQ22YWGbLHB0hr4lO5vpYU	false	sufficient binding region:851-1200	sufficient binding region:2111-3177	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99715	uniprotkb:O75923	intact:EBI-2528424|uniprotkb:O43853|uniprotkb:Q15955|uniprotkb:Q5VYK1|uniprotkb:Q5VYK2|uniprotkb:Q71UR3|uniprotkb:Q99716|ensembl:ENSP00000325146	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:coca1_human(display_long)|uniprotkb:COL12A1(gene name)|psi-mi:COL12A1(display_short)|uniprotkb:COL12A1L(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656693|imex:IM-16425-276	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004361.3|refseq:NP_542376.2|ensembl:ENSG00000111799(gene)|ensembl:ENST00000322507(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005595"(collagen type XII trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001791(Laminin G)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036465|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8948216|genbank_protein_gi:93141048(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:F8PJe9hehPjh3IhjfQKxFcfmvlc9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:16B8C62C2C1B31EB|rigid:6BsaQdDOfG/IVI5c00QuddzqwCE	false	sufficient binding region:543-3063(IPR003961)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17661	uniprotkb:O75923	intact:EBI-1055572|uniprotkb:Q15787|uniprotkb:Q8IZR1|uniprotkb:Q8IZR6|uniprotkb:Q8NES2|uniprotkb:Q8NEU6|uniprotkb:Q8TAC4|uniprotkb:Q8TCX2|uniprotkb:Q8TD99|uniprotkb:Q9UHN5|uniprotkb:Q9UJ80|uniprotkb:Q549R7|uniprotkb:Q549R8|uniprotkb:Q549R9|ensembl:ENSP00000363071	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:desm_human(display_long)|uniprotkb:DES(gene name)|psi-mi:DES(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656728|imex:IM-16425-278	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001918.3|ensembl:ENSG00000175084(gene)|ensembl:ENST00000373960(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005916"(fascia adherens)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|mint:P17661|reactome:R-HSA-390522|genbank_protein_gi:55749931(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:htjPzLKLLbRXxfKz9NUgMYMuIaY9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:299D7F1E72A9C634|rigid:prcvhcqwEoWP7C5Cduo2xD0lkms	false	sufficient binding region:333-470..470(IPR001664)	sufficient binding region:851-1200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q16760	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-719333|uniprotkb:Q14158|uniprotkb:Q6PK55|uniprotkb:Q8NG53|ensembl:ENSP00000264057|ensembl:ENSP00000487220	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:dgkd_human(display_long)|uniprotkb:Diglyceride kinase delta(gene name synonym)|uniprotkb:130 kDa diacylglycerol kinase(gene name synonym)|uniprotkb:DGKD(gene name)|psi-mi:DGKD(display_short)|uniprotkb:KIAA0145(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656746|imex:IM-16425-279	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_003639.2|refseq:NP_690618.2|ensembl:ENSG00000077044(gene)|ensembl:ENSG00000280873(gene)|ensembl:ENST00000264057(transcript)|ensembl:ENST00000628356(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010033"(response to organic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090038"(negative regulation of protein kinase C signaling)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037606|interpro:IPR037607|mint:Q16760|rcsb pdb:1R79|rcsb pdb:3BQ7|reactome:R-HSA-114508|dip:DIP-29646N|genbank_protein_gi:25777595(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:rMLPKsHWpeF6qbY0eBQcCeFyMo09606	intact-crc:BFAF8B5D627D4B99|rigid:OItHv/iYKK97rX3weppyPJBMmx0	false	sufficient binding region:851-1200	sufficient binding region:95-1214	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:O43143	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656763|imex:IM-16425-280	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)|genbank_protein_gi:68509925(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606	intact-crc:F655E13A1DCE3AE1|rigid:roZXuw9yrM+RnTTPQygjUdAiMVo	false	sufficient binding region:2-485	sufficient binding region:62-795(IPR002464)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75190	uniprotkb:O75923	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656782|imex:IM-16425-281	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:EA7DE0CCE367CA1A|rigid:wyXI8I/tkVUcph9tT9O/+PP8YIs	false	sufficient binding region:79-326	sufficient binding region:851-1200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26641	uniprotkb:O75923	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656818|imex:IM-16425-283	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|genbank_protein_gi:83656774(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:5BC4344A1090F72E|rigid:OdSBR42ATpuL8Mm2w5gg5j0u/io	false	sufficient binding region:229-437(IPR001662)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:P68104	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656799|imex:IM-16425-282	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1|genbank_protein_gi:83367078(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606	intact-crc:BCB4AACB5A81E2EF|rigid:36OCMLyyYe7IUVmqOUOjiMNUVXM	false	sufficient binding region:1145-2026	sufficient binding region:301-462..462(IPR004539)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14315	uniprotkb:O75923	intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656853|imex:IM-16425-285	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N|genbank_protein_gi:8885789(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:15FC0FC8C542E38D|rigid:AXAxTcZlU7nSpNikcl4AFyrqxao	false	sufficient binding region:1813-2725	sufficient binding region:851-1200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NZB2	uniprotkb:O75923	intact:EBI-1171960|uniprotkb:A6NGU0|uniprotkb:O60649|uniprotkb:Q14688|uniprotkb:Q4VXF4|uniprotkb:Q4VXF5|uniprotkb:Q4VXG2|uniprotkb:Q96I21|uniprotkb:Q9NZB1|uniprotkb:C4AMC6|uniprotkb:Q86V69|intact:EBI-2560129|ensembl:ENSP00000277165	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:f120a_human(display_long)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)|uniprotkb:Oxidative stress-associated Src activator(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656836|imex:IM-16425-284	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055427.2|refseq:XP_011516714.1|refseq:NP_001273651.1|refseq:NP_001273652.1|refseq:NP_001273653.1|ensembl:ENSG00000048828(gene)|ensembl:ENST00000277165(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q9NZB2|genbank_protein_gi:68299753(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:B73D63FE27E869BD|rigid:IlEBiAosbeSDuTp0SU/pS+Kk6Tc	false	sufficient binding region:433-1118	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BVP2	uniprotkb:O75923	intact:EBI-641642|uniprotkb:Q96SV6|uniprotkb:Q96SV7|uniprotkb:Q9UJY0|intact:EBI-2559594|intact:EBI-718302|uniprotkb:B2RDC1|uniprotkb:Q5PU80|intact:EBI-28973725|ensembl:ENSP00000395772	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:gnl3_human(display_long)|uniprotkb:Nucleolar GTP-binding protein 3(gene name synonym)|uniprotkb:Nucleostemin(gene name synonym)|uniprotkb:E2-induced gene 3 protein(gene name synonym)|uniprotkb:Novel nucleolar protein 47(gene name synonym)|uniprotkb:GNL3(gene name)|psi-mi:GNL3(display_short)|uniprotkb:E2IG3(gene name synonym)|uniprotkb:NS(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656870|imex:IM-16425-286	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000394799|ensembl:ENSP00000378278|ensembl:ENSP00000395772|refseq:NP_055181.3|refseq:NP_996561.1|refseq:NP_996562.1|ensembl:ENSG00000163938(gene)|ensembl:ENST00000418458(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030496"(midbody)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|interpro:IPR006073(GTP1/OBG)|interpro:IPR014813(GNL3L/Grn1 putative GTPase)|interpro:IPR027417|interpro:IPR030378|mint:Q9BVP2|reactome:R-HSA-6791226|genbank_protein_gi:45593129(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:c1DgvQoZ51edxvnCa6GFhfNRR7M9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:F09CA2F4EC700F2F|rigid:DMNO/DAHZNrm8BFiMfSzJ6hHWtA	false	sufficient binding region:75-549(IPR002917)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15046	uniprotkb:O75923	intact:EBI-356367|uniprotkb:A8MSK1|uniprotkb:Q9HB23|uniprotkb:O14946|uniprotkb:Q96J25|ensembl:ENSP00000303043|uniprotkb:D3DUK4	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:syk_human(display_long)|uniprotkb:KARS1(gene name)|psi-mi:KARS1(display_short)|uniprotkb:KARS(gene name synonym)|uniprotkb:KIAA0070(gene name synonym)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656888|imex:IM-16425-287	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123561.1|refseq:NP_005539.1|go:"GO:0016597"(amino acid binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0005739"(mitochondrion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018149|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR034762|interpro:IPR044136|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:Q15046|go:"GO:0006430"(lysyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|rcsb pdb:3BJU|rcsb pdb:4DPG|go:"GO:0010165"(response to X-ray)|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:6CHD|rcsb pdb:6ILD|rcsb pdb:6ILH|rcsb pdb:7EA9|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|ensembl:ENSG00000065427(gene)|ensembl:ENST00000302445(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002276"(basophil activation involved in immune response)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0003877"(ATP adenylyltransferase activity)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|dip:DIP-29725N|genbank_protein_gi:5031814(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YLjIdoUW7DiNp+Pj1OPg8jhnC5w9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:4427FA6140704C35|rigid:ivNmSLLVYkcCCkGTP6g6jPKeuxo	false	sufficient binding region:1-597	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60333	uniprotkb:O75923	intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|ensembl:ENSP00000366290|ensembl:ENSP00000502065|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656905|imex:IM-16425-288	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000054523(gene)|ensembl:ENST00000377086(transcript)|ensembl:ENST00000676179(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N|genbank_protein_gi:41393558(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:65A605F298F3A64E|rigid:95gwAP0Zqhkw/zXZ7jW6nY3hW0I	false	sufficient binding region:804-1816	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q9UBU8	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656922|imex:IM-16425-289	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847|genbank_protein_gi:33337721(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:28GQifqUMxwR32cneTXH+lpW4gM9606	intact-crc:FA4AE2152267D064|rigid:7LDZ3EA1XoNDCTqQ722PKoyByCw	false	sufficient binding region:2-485	sufficient binding region:92-362(IPR008676)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q9UBU8	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656940|imex:IM-16425-290	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847|genbank_protein_gi:33337721(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:28GQifqUMxwR32cneTXH+lpW4gM9606	intact-crc:695D255AD174FB45|rigid:7LDZ3EA1XoNDCTqQ722PKoyByCw	false	sufficient binding region:851-1200	sufficient binding region:53-362(IPR008676)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q00872	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656959|imex:IM-16425-291	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:ABA744037E1256A5|rigid:Q5qJ5gNvOaXzPwJ/AyvmU3mtqQ8	false	sufficient binding region:1145-2026	sufficient binding region:827-1141(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q00872	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656977|imex:IM-16425-292	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:9844EB2C8952A21F|rigid:Q5qJ5gNvOaXzPwJ/AyvmU3mtqQ8	false	sufficient binding region:2-485	sufficient binding region:133-1141(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q00872	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5656995|imex:IM-16425-293	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:CEBC2919E4E1A7C4|rigid:Q5qJ5gNvOaXzPwJ/AyvmU3mtqQ8	false	sufficient binding region:2-485	sufficient binding region:834-1141(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q00872	uniprotkb:O75923	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657013|imex:IM-16425-294	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:4D766E028AEA662F|rigid:Q5qJ5gNvOaXzPwJ/AyvmU3mtqQ8	false	sufficient binding region:697-1141(IPR007110)	sufficient binding region:851-1200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11055	uniprotkb:O75923	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657050|imex:IM-16425-296	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:20384D5B8567C743|rigid:A80pKsevonrgrxTaphoNsy4dfZU	false	sufficient binding region:1199-1940(IPR002928)	sufficient binding region:1145-2026	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q14324	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657031|imex:IM-16425-295	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:1845B1CC004A068A|rigid:ajN7ov2BG01srbeELRct+gMV8/Y	false	sufficient binding region:2-485	sufficient binding region:143-1141(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11055	uniprotkb:O75923	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657068|imex:IM-16425-297	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:DB5C8EBA582509C5|rigid:A80pKsevonrgrxTaphoNsy4dfZU	false	sufficient binding region:1423-1940(IPR002928)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:P52179	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-5353249|uniprotkb:Q14BD6|uniprotkb:Q6H969|uniprotkb:Q6ZUU0|ensembl:ENSP00000348821	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:myom1_human(display_long)|uniprotkb:MYOM1(gene name)|psi-mi:MYOM1(display_short)|uniprotkb:190 kDa connectin-associated protein(gene name synonym)|uniprotkb:190 kDa titin-associated protein(gene name synonym)|uniprotkb:Myomesin family member 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657086|imex:IM-16425-298	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	dip:DIP-59649N|refseq:NP_003794.3|refseq:NP_062830.1|ensembl:ENSG00000101605(gene)|ensembl:ENST00000356443(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P52179|rcsb pdb:2R15|rcsb pdb:2Y23|rcsb pdb:2Y25|rcsb pdb:3RBS|rcsb pdb:5FM4|rcsb pdb:5FM5|rcsb pdb:5FM8|rcsb pdb:6T3O|genbank_protein_gi:46249363(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:5lfd5o+54eyer647zxvU0LX1wpM9606	intact-crc:5A895F199C1B1CF0|rigid:AuWRSlO2T5qr0xzVxQQGvSSxSZc	false	sufficient binding region:2-485	sufficient binding region:410-1685(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:P52179	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-5353249|uniprotkb:Q14BD6|uniprotkb:Q6H969|uniprotkb:Q6ZUU0|ensembl:ENSP00000348821	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:myom1_human(display_long)|uniprotkb:MYOM1(gene name)|psi-mi:MYOM1(display_short)|uniprotkb:190 kDa connectin-associated protein(gene name synonym)|uniprotkb:190 kDa titin-associated protein(gene name synonym)|uniprotkb:Myomesin family member 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657105|imex:IM-16425-299	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	dip:DIP-59649N|refseq:NP_003794.3|refseq:NP_062830.1|ensembl:ENSG00000101605(gene)|ensembl:ENST00000356443(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P52179|rcsb pdb:2R15|rcsb pdb:2Y23|rcsb pdb:2Y25|rcsb pdb:3RBS|rcsb pdb:5FM4|rcsb pdb:5FM5|rcsb pdb:5FM8|rcsb pdb:6T3O|genbank_protein_gi:46249363(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:5lfd5o+54eyer647zxvU0LX1wpM9606	intact-crc:7DFCB7100512CB46|rigid:AuWRSlO2T5qr0xzVxQQGvSSxSZc	false	sufficient binding region:2-485	sufficient binding region:1194-1685(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54296	uniprotkb:O75923	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657141|imex:IM-16425-301	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:31418211(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:E7FB3D498F9C53B8|rigid:rNwMCwZFK6f2uhTnqeKv/FIZCP8	false	sufficient binding region:504-1465	sufficient binding region:851-1200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54296	uniprotkb:O75923	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657124|imex:IM-16425-300	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:31418211(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:D1E1CBA47D98CE3C|rigid:rNwMCwZFK6f2uhTnqeKv/FIZCP8	false	sufficient binding region:503-1465	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:P20929	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657158|imex:IM-16425-302	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:91E5C4DC9AF2B6A8|rigid:waTxFmvNU6HpJFKRRLzHtd9Oo3A	false	sufficient binding region:2-485	sufficient binding region:5316-6669(IPR000900)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929	uniprotkb:O75923	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657194|imex:IM-16425-304	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:EAA3BCF1DC116096|rigid:waTxFmvNU6HpJFKRRLzHtd9Oo3A	false	sufficient binding region:3765-6669(IPR000900)	sufficient binding region:851-1200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929	uniprotkb:O75923	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657176|imex:IM-16425-303	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:780C7DC5AACCCDEF|rigid:waTxFmvNU6HpJFKRRLzHtd9Oo3A	false	sufficient binding region:5329-6669(IPR000900)	sufficient binding region:851-1200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929	uniprotkb:O75923	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657212|imex:IM-16425-305	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:CAF25E880A75AFB6|rigid:waTxFmvNU6HpJFKRRLzHtd9Oo3A	false	sufficient binding region:4484-6669(IPR000900)	sufficient binding region:851-1200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q96CV9	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657247|imex:IM-16425-307	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:8D6C27F44527697D|rigid:/aYgkAFuAPKe9oj3BsUCkZ4YX4I	false	sufficient binding region:851-1200	sufficient binding region:346-577	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z494	uniprotkb:O75923	intact:EBI-2804263|uniprotkb:Q68D99|uniprotkb:Q8NCM5|uniprotkb:Q7Z493|uniprotkb:Q5JPE3|uniprotkb:Q96NK2|uniprotkb:Q5JPE6|uniprotkb:Q6NVH3|uniprotkb:Q96N70|uniprotkb:Q7Z492|uniprotkb:Q8N9R2|ensembl:ENSP00000338766	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:nphp3_human(display_long)|uniprotkb:KIAA2000(gene name synonym)|uniprotkb:NPHP3(gene name)|psi-mi:NPHP3(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657230|imex:IM-16425-306	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_694972.3|ensembl:ENSG00000113971(gene)|ensembl:ENST00000337331(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030324"(lung development)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000167"(regulation of planar cell polarity pathway involved in neural tube closure)|rcsb pdb:5L7K|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-HSA-5624138|genbank_protein_gi:34304359(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:7SitCJ9bwhu4VXh9FjX/wWCq0UQ9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:5E478179EBD1ABEC|rigid:LOR5CeOxwRkDefv7K9/UjVPvHWo	false	sufficient binding region:88-1330	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q13438	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657264|imex:IM-16425-308	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N|genbank_protein_gi:63252864(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	intact-crc:F776052B656D8819|rigid:Dzmnz77URfsliJGoGdiqsGwQSHs	false	sufficient binding region:2-485	sufficient binding region:506-667..667	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8N5U6	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657298|imex:IM-16425-310	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6|genbank_protein_gi:156630998(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:19E0FBB2251BEF8A|rigid:ZlacH9mkXM22SZCFiYaMqdpR26c	false	sufficient binding region:2-485	sufficient binding region:48-811(IPR001841)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:O43189	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657281|imex:IM-16425-309	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|genbank_protein_gi:13435396(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606	intact-crc:642AE61C91F1BC3B|rigid:boJGkeQDd+r5N5Gpfa5NdIZeIK8	false	sufficient binding region:1145-2026	sufficient binding region:499-567..567	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q99496	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657316|imex:IM-16425-311	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|genbank_protein_gi:54792140(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	intact-crc:7516C803F1358325|rigid:FotdABGaPSRMvHLYwIbd0zOX+Es	false	sufficient binding region:1145-2026	sufficient binding region:209-336	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHW9	uniprotkb:O75923	intact:EBI-2823282|uniprotkb:Q2VI00|uniprotkb:Q7Z2E7|uniprotkb:Q7Z4G5|uniprotkb:Q9UFR2|uniprotkb:Q8TDD4|uniprotkb:Q9Y665|uniprotkb:Q9Y642|uniprotkb:A0AV76|ensembl:ENSP00000346112|ensembl:ENSP00000453473|ensembl:ENSP00000454168	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:s12a6_human(display_long)|uniprotkb:SLC12A6(gene name)|psi-mi:SLC12A6(display_short)|uniprotkb:KCC3(gene name synonym)|uniprotkb:Electroneutral potassium-chloride cotransporter 3(gene name synonym)|uniprotkb:K-Cl cotransporter 3(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657350|imex:IM-16425-313	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035959.1|refseq:NP_001035960.1|refseq:NP_001035961.1|refseq:NP_001035962.1|refseq:NP_005126.1|refseq:NP_598408.1|rcsb pdb:7D90|rcsb pdb:7NGB|reactome:R-HSA-426117|reactome:R-HSA-5619039|ensembl:ENSG00000140199(gene)|ensembl:ENST00000354181(transcript)|ensembl:ENST00000558667(transcript)|ensembl:ENST00000560611(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071477"(cellular hypotonic salinity response)|go:"GO:0140157"(ammonium import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000076(K-Cl co-transporter)|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004842(Na-K-Cl cotransporter superfamily)|interpro:IPR018491|interpro:IPR030364|rcsb pdb:6M1Y|rcsb pdb:6M22|rcsb pdb:6Y5R|rcsb pdb:6Y5V|rcsb pdb:7AIN|rcsb pdb:7AIO|genbank_protein_gi:110224455(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ZNS+vbjlSeW9IjjaZoqhq/Z8IzA9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:74C113F02F557A4F|rigid:uSzZxDyklmMPeZdFcpaeGFRrq0s	false	sufficient binding region:15-1150	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q9Y3Z3	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657333|imex:IM-16425-312	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N|genbank_protein_gi:38016913(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	intact-crc:A2DFAC76C1D505D0|rigid:c7ntomhMDZXrC9dKxMyBXRV6JeQ	false	sufficient binding region:851-1200	sufficient binding region:1-626	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:O95295	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657367|imex:IM-16425-314	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:F7D3A2CCFDAAD872|rigid:CPZSgBkwSF644j933DxTx0N69l8	false	sufficient binding region:851-1200	sufficient binding region:34-136..136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21675	uniprotkb:O75923	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657401|imex:IM-16425-316	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N|genbank_protein_gi:20357587(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:E8D304E5B4882E29|rigid:aDNn9BYBFlJpVnqFMFiKCtVnFxE	false	sufficient binding region:1047-1872	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21675	uniprotkb:O75923	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657384|imex:IM-16425-315	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N|genbank_protein_gi:20357587(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:570F293948BF1945|rigid:aDNn9BYBFlJpVnqFMFiKCtVnFxE	false	sufficient binding region:1263-1872	sufficient binding region:1145-2026	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8WZ42	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657418|imex:IM-16425-317	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:65DC05A7719B4714|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:1145-2026	sufficient binding region:30723-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75923	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657454|imex:IM-16425-319	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:983D8BB3489A3080|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:29326-34350(IPR003961)	sufficient binding region:1145-2026	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8WZ42	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657436|imex:IM-16425-318	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:9106AE232171A53F|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:1145-2026	sufficient binding region:31574-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8WZ42	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657472|imex:IM-16425-320	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:3F20E563A70B6A5B|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:1145-2026	sufficient binding region:16421-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8WZ42	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657508|imex:IM-16425-322	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:3BF49AC75A0D08E0|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:2-485	sufficient binding region:2787-34350(IPR003006)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8WZ42	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657490|imex:IM-16425-321	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:3D857D0F0C3A94AF|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:2-485	sufficient binding region:8641-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8WZ42	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657544|imex:IM-16425-324	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:64B7FCECD26A802E|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:2-485	sufficient binding region:30437-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8WZ42	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657526|imex:IM-16425-323	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:A7B98DA085DBFEDF|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:2-485	sufficient binding region:22941-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75923	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657562|imex:IM-16425-325	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:6D8CD85241C13F7B|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:28032-34350(IPR003961)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75923	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657580|imex:IM-16425-326	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:00098C4B229B7924|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:27754-34350(IPR003961)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75923	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657616|imex:IM-16425-328	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:4C032682CC9F9DE6|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:29425-34350(IPR003961)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75923	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657598|imex:IM-16425-327	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:A2732683812171DC|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:28645-34350(IPR003599)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75923	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657634|imex:IM-16425-329	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:2DBE4B8424485C0E|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:18368-34350(IPR003961)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q8WZ42	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657670|imex:IM-16425-331	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:13FCD852E46F29FC|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:2-485	sufficient binding region:29802-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75923	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657652|imex:IM-16425-330	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:3B480310FABD2A57|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:30797-34350(IPR003961)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75923	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657688|imex:IM-16425-332	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:E99A9690D7A8A273|rigid:gWGw8XjOOfLiYdftiRzpJfQx0P4	false	sufficient binding region:27500-34350(IPR003599)	sufficient binding region:851-1200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12956	uniprotkb:O75923	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657723|imex:IM-16425-334	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N|genbank_protein_gi:51093847(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:0617C0FE62DF4593|rigid:Uz7uJVYqH8+ChIszV/CHiIqWJNk	false	sufficient binding region:404-609..609(IPR005160)	sufficient binding region:1145-2026	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:A4UGR9	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-3220204|ensembl:ENSP00000486198|uniprotkb:Q5MJ67|uniprotkb:B2BBS1|uniprotkb:B2BBS0|uniprotkb:Q86T79|uniprotkb:Q86T51|uniprotkb:Q86T38|uniprotkb:Q86T55|uniprotkb:Q86T53|uniprotkb:A0PJ94|uniprotkb:B3KVH0|uniprotkb:Q86T36|uniprotkb:Q8TBV6|uniprotkb:Q702N7|uniprotkb:Q8N3R5|uniprotkb:Q86T46|uniprotkb:Q53R52|uniprotkb:B2BBS4|uniprotkb:Q8N1M9|uniprotkb:Q86TB6|uniprotkb:J3KNB1	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:xirp2_human(display_long)|uniprotkb:XIRP2(gene name)|psi-mi:XIRP2(display_short)|uniprotkb:CMYA3(gene name synonym)|uniprotkb:Beta-xin(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 3(gene name synonym)|uniprotkb:Xeplin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657706|imex:IM-16425-333	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	ensembl:ENSG00000163092(gene)|ensembl:ENST00000628543(transcript)|go:"GO:0003281"(ventricular septum development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|interpro:IPR012510(Actin Binding Sixteen Amino Acid)|interpro:IPR030072|interpro:IPR030107|rcsb pdb:4F14|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001073278.1|refseq:NP_001186072.1|refseq:NP_001186073.1|refseq:NP_001186074.1|refseq:NP_689594.4|ensembl:ENST00000409043|ensembl:ENSP00000386454|ensembl:ENST00000409195|ensembl:ENSP00000386840|ensembl:ENST00000409273|ensembl:ENSP00000387255|ensembl:ENST00000409605|ensembl:ENSP00000386981|ensembl:ENST00000409728|ensembl:ENSP00000486198|ensembl:ENSP00000386619|genbank_protein_gi:119372316(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:YqOEBAnOUca+7Xt8u5ePKv//RzI9606	intact-crc:6BC233BBCD62C75B|rigid:skdJFLh/bBmhAQSZye3UBN1P5dM	false	sufficient binding region:2-485	sufficient binding region:3204-3374	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12956	uniprotkb:O75923	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657742|imex:IM-16425-335	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N|genbank_protein_gi:51093847(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:C2FE13D00F948081|rigid:Uz7uJVYqH8+ChIszV/CHiIqWJNk	false	sufficient binding region:23-609(IPR005161)	sufficient binding region:2-485	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17027	uniprotkb:O75923	intact:EBI-5657766|uniprotkb:Q8NDP5|uniprotkb:Q96IT3|uniprotkb:Q9UG42|ensembl:ENSP00000349796|ensembl:ENSP00000377171|ensembl:ENSP00000387673	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	psi-mi:znf23_human(display_long)|uniprotkb:KOX16(gene name synonym)|uniprotkb:ZNF359(gene name synonym)|uniprotkb:ZNF612(gene name synonym)|uniprotkb:Zinc finger protein 359(gene name synonym)|uniprotkb:Zinc finger protein 612(gene name synonym)|uniprotkb:Zinc finger protein KOX16(gene name synonym)|uniprotkb:ZNF23(gene name)|psi-mi:ZNF23(display_short)	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657761|imex:IM-16425-336	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291421.1|refseq:NP_001291422.1|refseq:NP_001291423.1|refseq:NP_666016.1|ensembl:ENSG00000167377(gene)|ensembl:ENST00000357254(transcript)|ensembl:ENST00000393539(transcript)|ensembl:ENST00000428724(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P17027|reactome:R-HSA-212436|genbank_protein_gi:23308736(identity)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:N5hIISReQVVo0kOTNVvoUS59+fk9606	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	intact-crc:F518F6D463FABFEC|rigid:MrAJfRJ9tHbvK0jJXNcCOlUwIn0	false	sufficient binding region:511-643..643(IPR007087)	sufficient binding region:1145-2026	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NFD5	uniprotkb:P06733	intact:EBI-679921|uniprotkb:Q5JRD1|uniprotkb:Q5VYC4|uniprotkb:Q8IZY8|uniprotkb:Q8TEV0|uniprotkb:Q8TF02|uniprotkb:Q99491|uniprotkb:Q9ULI5|intact:EBI-2560572|ensembl:ENSP00000055163	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:ari1b_human(display_long)|uniprotkb:BAF250B(gene name synonym)|uniprotkb:Osa homolog 2(gene name synonym)|uniprotkb:p250R(gene name synonym)|uniprotkb:BRG1-binding protein hELD/OSA1(gene name synonym)|uniprotkb:BRG1-associated factor 250b(gene name synonym)|uniprotkb:ARID1B(gene name)|psi-mi:ARID1B(display_short)|uniprotkb:DAN15(gene name synonym)|uniprotkb:KIAA1235(gene name synonym)|uniprotkb:OSA2(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657803|imex:IM-16425-338	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001333742.1|refseq:NP_059989.2|refseq:NP_065783.3|ensembl:ENSG00000049618(gene)|ensembl:ENST00000350026(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR021906|interpro:IPR033388|interpro:IPR036431|interpro:IPR038040|mint:Q8NFD5|rcsb pdb:2CXY|rcsb pdb:2EH9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|genbank_protein_gi:40068461(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:BeWhuwPk5f6HN+yasFEJRpkbM6A9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:408E788098F76AB9|rigid:2YBxW+pgwY5W2fIGkrctGZnNVi0	false	sufficient binding region:1758-2236	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04075	uniprotkb:P06733	intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657785|imex:IM-16425-337	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263|genbank_protein_gi:34577108(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:1D3F655081C0B820|rigid:MfckHx4KITiWIzlyVj6YZZfcv94	false	sufficient binding region:1-364(IPR000741)	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P41182	uniprotkb:P06733	intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657820|imex:IM-16425-339	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657|genbank_protein_gi:21040335(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:A3040B865FE8E613|rigid:UDEStWfG+pn/9Buy8nO5P+QKYzg	false	sufficient binding region:213-706	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:Q05707	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-2528599|uniprotkb:B2RU07|uniprotkb:O00260|uniprotkb:O00261|uniprotkb:O00262|uniprotkb:Q05708|uniprotkb:Q5XJ18|uniprotkb:Q96C67|uniprotkb:Q9UDF6|ensembl:ENSP00000297848	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:coea1_human(display_long)|uniprotkb:COL14A1(gene name)|psi-mi:COL14A1(display_short)|uniprotkb:UND(gene name synonym)|uniprotkb:Undulin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657854|imex:IM-16425-341	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	refseq:XP_016869298.1|refseq:NP_066933.1|refseq:XP_005251116.1|refseq:XP_006716714.1|ensembl:ENSG00000187955(gene)|ensembl:ENST00000297848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005596"(collagen type XIV trimer)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001791(Laminin G)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036465|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8948216|genbank_protein_gi:55743095(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:8eQ55YOi3IK4OWPI57s3ak2q4bg9606	intact-crc:B654729426721D2A|rigid:xson82HNmDUmV3VCaIotCcxzJPY	false	sufficient binding region:126-371	sufficient binding region:739-1796(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P45973	uniprotkb:P06733	intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657837|imex:IM-16425-340	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|genbank_protein_gi:6912291(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:B4B4069890BADFB0|rigid:xlJFbtYAXNHjyrbsFrdrdtZ5WRE	false	sufficient binding region:1-191	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17661	uniprotkb:P06733	intact:EBI-1055572|uniprotkb:Q15787|uniprotkb:Q8IZR1|uniprotkb:Q8IZR6|uniprotkb:Q8NES2|uniprotkb:Q8NEU6|uniprotkb:Q8TAC4|uniprotkb:Q8TCX2|uniprotkb:Q8TD99|uniprotkb:Q9UHN5|uniprotkb:Q9UJ80|uniprotkb:Q549R7|uniprotkb:Q549R8|uniprotkb:Q549R9|ensembl:ENSP00000363071	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:desm_human(display_long)|uniprotkb:DES(gene name)|psi-mi:DES(display_short)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657872|imex:IM-16425-342	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001918.3|ensembl:ENSG00000175084(gene)|ensembl:ENST00000373960(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005916"(fascia adherens)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|mint:P17661|reactome:R-HSA-390522|genbank_protein_gi:55749931(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:htjPzLKLLbRXxfKz9NUgMYMuIaY9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:92E1DCDFEF5D5A42|rigid:1POERo1za9Z/2rM9vXGjUbq51gQ	false	sufficient binding region:185-470	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14315	uniprotkb:P06733	intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657906|imex:IM-16425-344	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N|genbank_protein_gi:8885789(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:2F25B6BFD2736276|rigid:EohoAXuE+/Jb5QUn/OV2lZrWAuY	false	sufficient binding region:1691-2725(IPR001298)	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:Q13642	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657889|imex:IM-16425-343	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	intact-crc:E9E21408C23CAEB4|rigid:7sWId/KoM4ducwit5nf/M9shbUg	false	sufficient binding region:126-371	sufficient binding region:89-323	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:Q8NEA6	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-744456|uniprotkb:B1AL19|uniprotkb:Q1PHK5|ensembl:ENSP00000325494|ensembl:ENSP00000507306	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:glis3_human(display_long)|uniprotkb:GLI-similar 3(gene name synonym)|uniprotkb:Zinc finger protein 515(gene name synonym)|uniprotkb:GLIS3(gene name)|psi-mi:GLIS3(display_short)|uniprotkb:ZNF515(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657924|imex:IM-16425-345	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	refseq:NP_001035878.1|refseq:NP_689842.3|refseq:XP_011516065.1|refseq:XP_011516066.1|refseq:XP_011516068.1|ensembl:ENSP00000325494|ensembl:ENST00000381971|ensembl:ENSP00000371398|ensembl:ENSP00000507306|refseq:XP_005251443.1|ensembl:ENSG00000107249(gene)|ensembl:ENST00000324333(transcript)|ensembl:ENST00000682749(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030405|interpro:IPR036236|interpro:IPR043359|mint:Q8NEA6|refseq:XP_016869850.1|genbank_protein_gi:109637783(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:Lw/ndmcKfz+wO+0eEheRj4Y0fXM9606	intact-crc:85AE4BC2EFF127E9|rigid:luEbhndP8PG5znCRUi+u6Txu7x0	false	sufficient binding region:126-371	sufficient binding region:464-775	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52789	uniprotkb:P06733	intact:EBI-741469|uniprotkb:Q8WU87|uniprotkb:Q9UN82|ensembl:ENSP00000290573|uniprotkb:D6W5J2	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:hxk2_human(display_long)|uniprotkb:Hexokinase type II(gene name synonym)|uniprotkb:Muscle form hexokinase(gene name synonym)|uniprotkb:HK2(gene name)|psi-mi:HK2(display_short)|uniprotkb:Hexokinase-B(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657958|imex:IM-16425-347	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019158"(mannokinase activity)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:P52789|rcsb pdb:2NZT|rcsb pdb:5HEX|rcsb pdb:5HFU|rcsb pdb:5HG1|reactome:R-HSA-70171|go:"GO:0008865"(fructokinase activity)|ensembl:ENSG00000159399(gene)|ensembl:ENST00000290573(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007595"(lactation)|go:"GO:0008637"(apoptotic mitochondrial changes)|refseq:NP_000180.2|dip:DIP-50110N|genbank_protein_gi:40806188(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:99w5KbKmsqMoorQz/wot6z6t2WM9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:0E5DD930B9B2C505|rigid:GoXt51sH3WxYbFlv7olcqxHzLDE	false	sufficient binding region:499-917(IPR001312)	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:Q9UBP5	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-750630|ensembl:ENSP00000357348	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:hey2_human(display_long)|uniprotkb:Cardiovascular helix-loop-helix factor 1(gene name synonym)|uniprotkb:Hairy and enhancer of split-related protein 2(gene name synonym)|uniprotkb:Hairy-related transcription factor 2(gene name synonym)|uniprotkb:HES-related repressor protein 2(gene name synonym)|uniprotkb:Protein gridlock homolog(gene name synonym)|uniprotkb:HEY2(gene name)|psi-mi:HEY2(display_short)|uniprotkb:CHF1(gene name synonym)|uniprotkb:GRL(gene name synonym)|uniprotkb:HERP(gene name synonym)|uniprotkb:HERP1(gene name synonym)|uniprotkb:HRT2(gene name synonym)|uniprotkb:BHLHB32(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 32(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657941|imex:IM-16425-346	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	refseq:NP_036391.1|ensembl:ENSG00000135547(gene)|ensembl:ENST00000368364(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003186"(tricuspid valve morphogenesis)|go:"GO:0003195"(tricuspid valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003199"(endocardial cushion to mesenchymal transition involved in heart valve formation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0035910"(ascending aorta morphogenesis)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036304"(umbilical cord morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060842"(arterial endothelial cell differentiation)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060977"(coronary vasculature morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0072359"(circulatory system development)|go:"GO:0090102"(cochlea development)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2000723"(negative regulation of cardiac vascular smooth muscle cell differentiation)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|go:"GO:2001212"(regulation of vasculogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-8940973|reactome:R-HSA-9013508|reactome:R-HSA-9013695|go:"GO:0060633"(negative regulation of transcription initiation from RNA polymerase II promoter)|genbank_protein_gi:105990529(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:2yzuRFQ4w90/mIrzCXFZ6U19xPE9606	intact-crc:A496287251C8CCE9|rigid:8JHA6jlR8S9FSLj0CwR2+yy8qK0	false	sufficient binding region:126-371	sufficient binding region:1-337	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:P08238	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657976|imex:IM-16425-348	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N|genbank_protein_gi:20149593(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:wOsW7C10v2oMsM+REE38K6PAan09606	intact-crc:8ABE198CF14A682D|rigid:jdyI+WV8Ee2pgO5B6B6w+DKA08M	false	sufficient binding region:126-371	sufficient binding region:251-724	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05556	uniprotkb:P06733	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658011|imex:IM-16425-350	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191|genbank_protein_gi:19743818(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:492AF575C3A29079|rigid:fUu3+pDZOCB6qpEEupvG7lI555A	false	sufficient binding region:1-798(IPR003659)	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:P11142	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5657993|imex:IM-16425-349	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|genbank_protein_gi:24234684(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:992023579676C461|rigid:3+o2q0TGb0bW9bTY2VzT6XK7jb4	false	sufficient binding region:126-371	sufficient binding region:603-646..646(IPR001023)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y6Y0	uniprotkb:P06733	intact:EBI-715774|uniprotkb:Q1G4T6|uniprotkb:Q1G4T7|uniprotkb:Q5TF75|uniprotkb:Q6NW38|uniprotkb:Q7LCG2|uniprotkb:Q9NZX0|uniprotkb:Q9Y480|uniprotkb:A8K8R6|ensembl:ENSP00000356468	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:ns1bp_human(display_long)|uniprotkb:Aryl hydrocarbon receptor-associated protein 3(gene name synonym)|uniprotkb:IVNS1ABP(gene name)|psi-mi:IVNS1ABP(display_short)|uniprotkb:ARA3(gene name synonym)|uniprotkb:FLARA3(gene name synonym)|uniprotkb:KIAA0850(gene name synonym)|uniprotkb:NS1(gene name synonym)|uniprotkb:NS1BP(gene name synonym)|uniprotkb:HSPC068(orf name)|uniprotkb:KLHL39(gene name synonym)|uniprotkb:Kelch-like protein 39(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658030|imex:IM-16425-351	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006460.2|ensembl:ENSG00000116679(gene)|ensembl:ENST00000367498(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008380"(RNA splicing)|go:"GO:0009615"(response to virus)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017096(Kelch-like protein, gigaxonin)|rcsb pdb:5YY8|rcsb pdb:6N34|rcsb pdb:6N3H|interpro:IPR015915(Kelch-type beta propeller)|genbank_protein_gi:54144638(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:27jzoex7cmDEgCPCpPMGbZ0pj489606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:47264BD592804655|rigid:oQXupBzEfKVifb5tNLPS23FuTNc	false	sufficient binding region:256-642	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q496Y0	uniprotkb:P06733	intact:EBI-2690768|uniprotkb:Q9H647|uniprotkb:Q5JPN6|uniprotkb:Q8NB00|ensembl:ENSP00000360690	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:lonf3_human(display_long)|uniprotkb:RNF127(gene name synonym)|uniprotkb:RING finger protein 127(gene name synonym)|uniprotkb:LONRF3(gene name)|psi-mi:LONRF3(display_short)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658064|imex:IM-16425-353	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027026.1|refseq:NP_079054.3|ensembl:ENSG00000175556(gene)|ensembl:ENST00000371628(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019734|genbank_protein_gi:73747839(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Od2Ql3pSw31BxS87fLal1iEl7289606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:98FEC4AFE81CB114|rigid:g1Tz/ewdB5OXp5ReZFl6LKwTa+w	false	sufficient binding region:422-759(IPR001841)	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:Q9Y2K7	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658047|imex:IM-16425-352	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N|genbank_protein_gi:16306579(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:FWcxfQykne+IrmtpDxZ218sEURc9606	intact-crc:94BB7E4610E36991|rigid:HioLpZO4lf8oD9CEOxTJZ7UN3is	false	sufficient binding region:126-371	sufficient binding region:431-1162	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:Q9UHV7	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-394440|uniprotkb:O60334|uniprotkb:B2RU05|ensembl:ENSP00000380888	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:med13_human(display_long)|uniprotkb:TRAP240(gene name synonym)|uniprotkb:MED13(gene name)|psi-mi:MED13(display_short)|uniprotkb:ARC250(gene name synonym)|uniprotkb:KIAA0593(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex component DRIP250(gene name synonym)|uniprotkb:Activator-recruited cofactor 250 kDa component(gene name synonym)|uniprotkb:THRAP1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658082|imex:IM-16425-354	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	refseq:NP_005112.2|ensembl:ENSG00000108510(gene)|ensembl:ENST00000397786(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR009401(TRAP240)|interpro:IPR041285|mint:Q9UHV7|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31468N|genbank_protein_gi:102468716(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:ZNWwmsetsKLA56joRzRL0UKjq9Y9606	intact-crc:A0A1BC8EAD75B9B6|rigid:AKpDWf6ufyMelSKN3QrgX1q6nj4	false	sufficient binding region:126-371	sufficient binding region:1526-2174	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07237	uniprotkb:P06733	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658116|imex:IM-16425-356	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N|genbank_protein_gi:121256637(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:59F7BF5E51BCDFE9|rigid:PHWeK5Mo0oQwwhrbvMRMN+pe0Ag	false	sufficient binding region:121-508(IPR005792)	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:O75376	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|ensembl:ENSP00000268712|uniprotkb:B3DLF8	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658099|imex:IM-16425-355	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	dip:DIP-29402N|ensembl:ENSP00000268712|ensembl:ENST00000395848|ensembl:ENSP00000379189|ensembl:ENST00000395851|ensembl:ENSP00000379192|ensembl:ENSG00000141027(gene)|ensembl:ENST00000268712(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|rcsb pdb:3H52|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:XP_011522388.1|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1|genbank_protein_gi:22538460(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606	intact-crc:3C52EA86FDC378DB|rigid:/4kSii7ig49mNT5TdS7hTLJc2Po	false	sufficient binding region:126-371	sufficient binding region:92-2440	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:Q16537	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658151|imex:IM-16425-358	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1|genbank_protein_gi:31083295(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606	intact-crc:7A1EE4C2ABAECDB0|rigid:bUUAqmMOm2CfGfo0wfP2dXdTqT4	false	sufficient binding region:126-371	sufficient binding region:34-467(IPR002554)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N7H5	uniprotkb:P06733	intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658134|imex:IM-16425-357	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N|genbank_protein_gi:42476168(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:DC47373152CEA2ED|rigid:HGBy1FTIZQwgJUDSgddYa/J+hzY	false	sufficient binding region:181-531	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:Q01105	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658169|imex:IM-16425-359	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation)|genbank_protein_gi:34604765(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606	intact-crc:262A357624127123|rigid:p0FZy9Ik5Kh7DYol4bdroBsamuY	false	sufficient binding region:126-371	sufficient binding region:153-290	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:P28347	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-529156|intact:EBI-9089898|uniprotkb:A4FUP2|uniprotkb:E7EV65|intact:EBI-11138289|ensembl:ENSP00000435233	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:tead1_human(display_long)|uniprotkb:TEA domain family member 1(gene name synonym)|uniprotkb:Protein GT-IIC(gene name synonym)|uniprotkb:Transcription factor 13(gene name synonym)|uniprotkb:NTEF-1(gene name synonym)|uniprotkb:TEAD1(gene name)|psi-mi:TEAD1(display_short)|uniprotkb:TCF13(gene name synonym)|uniprotkb:TEF1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658203|imex:IM-16425-361	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	refseq:NP_068780.2|dip:DIP-34360N|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035329"(hippo signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR038096|interpro:IPR041086|rcsb pdb:2HZD|rcsb pdb:3KYS|rcsb pdb:4RE1|rcsb pdb:4Z8E|rcsb pdb:5NNX|rcsb pdb:6HIL|rcsb pdb:6IM5|rcsb pdb:7CMM|reactome:R-HSA-2032785|reactome:R-HSA-8951671|reactome:R-HSA-9619665|ensembl:ENSG00000187079(gene)|ensembl:ENST00000527636(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|genbank_protein_gi:11386150(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2015/09/01	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:NIFPFGqbBqT0PRutdwX8TJ4v/AE9606	intact-crc:F5180662F4253C28|rigid:ZOofQmkMt6COJWkH1JWit7gmFas	false	sufficient binding region:126-371	sufficient binding region:1-426	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92966	uniprotkb:P06733	intact:EBI-1760638|uniprotkb:D3DRI8|uniprotkb:Q2VPI6|uniprotkb:Q5T285|ensembl:ENSP00000370200|ensembl:ENSP00000432393|ensembl:ENSP00000436699|ensembl:ENSP00000483273	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:snpc3_human(display_long)|uniprotkb:SNAPC3(gene name)|psi-mi:SNAPC3(display_short)|uniprotkb:SNAP50(gene name synonym)|uniprotkb:Small nuclear RNA-activating complex polypeptide 3(gene name synonym)|uniprotkb:snRNA-activating protein complex 50 kDa subunit(gene name synonym)|uniprotkb:Proximal sequence element-binding transcription factor subunit beta(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658186|imex:IM-16425-360	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001034786.1|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016604"(nuclear body)|go:"GO:0019185"(snRNA-activating protein complex)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|interpro:IPR022042|ensembl:ENSG00000164975(gene)|ensembl:ENST00000380821(transcript)|ensembl:ENST00000467062(transcript)|ensembl:ENST00000490969(transcript)|ensembl:ENST00000610884(transcript)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003681"(bent DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|refseq:XP_016870545.1|refseq:XP_016870546.1|genbank_protein_gi:89242151(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rBz/aJhgpfII7MmvRgcuVsr9Q+A9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:5A5B6328BB1AAC1F|rigid:sdPUjOd+BsRjnovFM3bYCqH/a4s	false	sufficient binding region:23-411	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:Q8WZ42	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658220|imex:IM-16425-362	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:F39305F3131E1688|rigid:amccLQFDjDSaUHCvUQo76Ugrztc	false	sufficient binding region:126-371	sufficient binding region:27456-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P06733	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658238|imex:IM-16425-363	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:2269AE760E8FE1BF|rigid:amccLQFDjDSaUHCvUQo76Ugrztc	false	sufficient binding region:20661-34350(IPR003961)	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63104	uniprotkb:P06733	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658275|imex:IM-16425-365	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|genbank_protein_gi:80477444(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:6B035EBD86E7CC5B|rigid:afhfALbZ9Xkk9HtfqK8jPZ2RFUg	false	sufficient binding region:1-245	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:Q8WZ42	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658257|imex:IM-16425-364	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:58D28BE6C053E704|rigid:amccLQFDjDSaUHCvUQo76Ugrztc	false	sufficient binding region:126-371	sufficient binding region:30403-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NCP5	uniprotkb:P06733	intact:EBI-5658292|uniprotkb:Q86VJ7|uniprotkb:Q6IPT8|uniprotkb:Q86XX5|intact:EBI-28972467	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:zbt44_human(display_long)|uniprotkb:BTB/POZ domain-containing protein 15(gene name synonym)|uniprotkb:BTBD15(gene name synonym)|uniprotkb:ZNF851(gene name synonym)|uniprotkb:Zinc finger protein 851(gene name synonym)|uniprotkb:ZBTB44(gene name)|psi-mi:ZBTB44(display_short)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658299|imex:IM-16425-366	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q8NCP5|ensembl:ENST00000445008|ensembl:ENSP00000408079|ensembl:ENSG00000196323|ensembl:ENST00000525842|ensembl:ENSP00000433457|ensembl:ENST00000530205|ensembl:ENSP00000434177|refseq:NP_001288027.1|refseq:NP_001288028.1|interpro:IPR036236|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_054874.3|refseq:XP_016873112.1|genbank_protein_gi:21040474(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:xewgUIEkS1YVch+LlFi+bSwFZ2Y9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:0C923B24B580C422|rigid:SYTwSVXim5HkJYQm182As2MwoNo	false	sufficient binding region:287-570	sufficient binding region:126-371	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04075	uniprotkb:P13929	intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658316|imex:IM-16425-367	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263|genbank_protein_gi:34577108(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:79B9CCA592307376|rigid:QeAoKqXgSsA0NpDm8oOwnPXZUas	false	sufficient binding region:102-364(IPR000741)	sufficient binding region:1-434	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15924	uniprotkb:P13929	intact:EBI-355041|uniprotkb:O75993|uniprotkb:Q14189|uniprotkb:Q9UHN4|uniprotkb:B2RTT2|uniprotkb:D7RX09|ensembl:ENSP00000369129	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:desp_human(display_long)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658351|imex:IM-16425-369	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001305963.1|refseq:NP_001008844.1|refseq:NP_004406.2|go:"GO:0014704"(intercalated disc)|go:"GO:0005916"(fascia adherens)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:P15924|rcsb pdb:1LM5|rcsb pdb:1LM7|rcsb pdb:3R6N|rcsb pdb:5DZZ|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-109N|genbank_protein_gi:58530839(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:73E78AC029966B7F|rigid:3qYopuUMfpp8oimjdhYUox8VFl4	false	sufficient binding region:487-2871	sufficient binding region:1-434	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14203	uniprotkb:P13929	intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658334|imex:IM-16425-368	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N|genbank_protein_gi:13259509(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:0EC38F87FDC77D57|rigid:L0jTAz+N4NNEFY0Gmikb2RBOD88	false	sufficient binding region:430-1278	sufficient binding region:1-434	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13929	uniprotkb:P13929	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658368|imex:IM-16425-370	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:33878987(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:181D71C9E520BEFE|rigid:FjGEH7HjHXa7jZaX9RYrwZprqcY	false	sufficient binding region:192-434	sufficient binding region:1-434	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13929	uniprotkb:O60229	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	intact:EBI-949233|ensembl:ENSP00000353109|intact:EBI-1104807|uniprotkb:Q8TBQ5|uniprotkb:Q9NSZ4|uniprotkb:Q9Y2A5|uniprotkb:Q6ZN45|uniprotkb:A8MSI4|uniprotkb:J3QSW6|intact:EBI-3866438|uniprotkb:C9JQ37	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:kalrn_human(display_long)|uniprotkb:KALRN(gene name)|psi-mi:KALRN(display_short)|uniprotkb:DUET(gene name synonym)|uniprotkb:DUO(gene name synonym)|uniprotkb:HAPIP(gene name synonym)|uniprotkb:TRAD(gene name synonym)|uniprotkb:Huntingtin-associated protein-interacting protein(gene name synonym)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658385|imex:IM-16425-371	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036865|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-5687128|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013408|ensembl:ENSG00000160145(gene)|ensembl:ENST00000360013(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|refseq:NP_001309929.1|refseq:NP_001019831.2|refseq:NP_003938.1|refseq:NP_008995.2|refseq:NP_001309930.1|refseq:NP_001309917.1|refseq:NP_001309918.1|refseq:NP_001309923.1|refseq:NP_001309924.1|refseq:NP_001309925.1|refseq:NP_001309926.1|refseq:NP_001309927.1|refseq:NP_001309928.1|genbank_protein_gi:68362739(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2019/08/05	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	rogid:E7oPA6ps2iq0KD8jlTCm/mNQj949606	intact-crc:5393AB1D7E3136D9|rigid:IpiUlmIsrWqdTqybCvwwlCgZWlI	false	sufficient binding region:1-434	sufficient binding region:617-2986	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NCE2	uniprotkb:P13929	intact:EBI-5658424|uniprotkb:Q86VK9|uniprotkb:Q6PIZ4|uniprotkb:Q8IYK1|uniprotkb:Q0JU83|uniprotkb:Q9H6C0|uniprotkb:Q6QE21|uniprotkb:Q0JTH5|uniprotkb:Q8TCM7|ensembl:ENSP00000296003	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:mtmre_human(display_long)|uniprotkb:C3orf29(gene name synonym)|uniprotkb:HCV NS5A-transactivated protein 4 splice variant A-binding protein 1(gene name synonym)|uniprotkb:hJumpy(gene name synonym)|uniprotkb:MTMR14(gene name)|psi-mi:MTMR14(display_short)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658419|imex:IM-16425-373	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070993.1|refseq:NP_001070994.1|refseq:NP_071930.2|ensembl:ENSG00000163719(gene)|ensembl:ENST00000296003(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016236"(macroautophagy)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR039802|interpro:IPR039803|mint:Q8NCE2|reactome:R-HSA-1632852|reactome:R-HSA-1660499|genbank_protein_gi:117938273(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ftagAuEsNaEzJHotTrA3OjWPPN09606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:48953EBE30CA9AEA|rigid:XfWSOOaOPC0kEOnL/6uDiapmHho	false	sufficient binding region:8-650	sufficient binding region:1-434	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13929	uniprotkb:P49641	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	intact:EBI-713521|uniprotkb:Q13754|uniprotkb:A6NH12|uniprotkb:A8K1E8|ensembl:ENSP00000452948|ensembl:ENSP00000353655	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:ma2a2_human(display_long)|uniprotkb:Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase(gene name synonym)|uniprotkb:Mannosidase alpha class 2A member 2(gene name synonym)|uniprotkb:MAN2A2(gene name)|psi-mi:MAN2A2(display_short)|uniprotkb:MANA2X(gene name synonym)|uniprotkb:Alpha-mannosidase IIx(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658402|imex:IM-16425-372	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	refseq:NP_006113.2|refseq:XP_016877674.1|ensembl:ENST00000360468(transcript)|ensembl:ENST00000559717(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004559"(alpha-mannosidase activity)|go:"GO:0004572"(mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016799"(hydrolase activity, hydrolyzing N-glycosyl compounds)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000602(Glycoside hydrolase, family 38, core)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR011682(Glycosyl hydrolases 38, C-terminal)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR015341(Glycoside hydrolase, family 38, central region)|interpro:IPR027291|interpro:IPR028995|interpro:IPR037094|reactome:R-HSA-6811438|reactome:R-HSA-975578|ensembl:ENSG00000196547(gene)|genbank_protein_gi:51477715(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	rogid:na9+2i0/6cG74cZzVOx4y3npBtE9606	intact-crc:8CC9BE3F56EBACA2|rigid:nlLNfWaIX2jEZ2aqeQcSSxGfT1k	false	sufficient binding region:1-434	sufficient binding region:960-1150	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13929	uniprotkb:P20929	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658448|imex:IM-16425-374	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:C9EBC5329D1877B9|rigid:UY5FQZRcs2YjDlmAQh4JQGCWvWg	false	sufficient binding region:1-434	sufficient binding region:5328-6669	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14618	uniprotkb:P13929	intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658482|imex:IM-16425-376	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1|genbank_protein_gi:33286421(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:5D028267030FB211|rigid:PNhyAqVJ4uoegB5XgHVb+QUOyrE	false	sufficient binding region:198-531	sufficient binding region:1-434	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36871	uniprotkb:P13929	intact:EBI-2861475|uniprotkb:Q5BKZ9|uniprotkb:Q96J40|uniprotkb:Q9NTY4|uniprotkb:Q6NW22|uniprotkb:Q86U74|uniprotkb:Q16105|uniprotkb:B2R5N9|uniprotkb:B4DPV0|uniprotkb:Q16106|ensembl:ENSP00000360125	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:pgm1_human(display_long)|uniprotkb:PGM1(gene name)|psi-mi:PGM1(display_short)|uniprotkb:Glucose phosphomutase 1(gene name synonym)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658465|imex:IM-16425-375	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166289.1|refseq:NP_001166290.1|refseq:NP_002624.2|dip:DIP-60903N|reactome:R-HSA-5609974|reactome:R-HSA-6798695|reactome:R-HSA-3322077|ensembl:ENSG00000079739(gene)|ensembl:ENST00000371084(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900|rcsb pdb:5EPC|rcsb pdb:5F9C|rcsb pdb:5HSH|rcsb pdb:5JN5|rcsb pdb:5TR2|rcsb pdb:5VBI|rcsb pdb:5VEC|rcsb pdb:5VG7|rcsb pdb:5VIN|rcsb pdb:6SNO|rcsb pdb:6SNP|rcsb pdb:6SNQ|rcsb pdb:6UIQ|rcsb pdb:6UO6|genbank_protein_gi:21361620(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:K9cGu3lfysJ4hVP0S0jewZsZjSE9606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:6FFADFD42DDDF966|rigid:q1YVQ2a0ULVIDqe4F6SdxTzL8Wg	false	sufficient binding region:1-562	sufficient binding region:1-434	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13929	uniprotkb:O95295	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658499|imex:IM-16425-377	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:04635159C01CE085|rigid:AdxujC2U1ZdFGo0sleorPwwnofk	false	sufficient binding region:1-434	sufficient binding region:34-136..136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P13929	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658534|imex:IM-16425-379	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:AF5FA1EF2D6FF75F|rigid:NI29XG61pAcAqIpe3q5ULKKInhQ	false	sufficient binding region:21905-34350(IPR003961)	sufficient binding region:1-434	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11277	uniprotkb:P13929	intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658516|imex:IM-16425-378	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|genbank_protein_gi:67782318(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:16554591(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:48C9CE297E0ADA98|rigid:uFlBbppgLSoVjlJvBqIcAkslQrg	false	sufficient binding region:1675-2137(IPR002017)	sufficient binding region:1-434	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35241	uniprotkb:P15311	intact:EBI-2514878|ensembl:ENSP00000496503|uniprotkb:Q86Y61|uniprotkb:A7YIK0|uniprotkb:A7YIK3|uniprotkb:A7YIJ8|uniprotkb:B7Z9U6|uniprotkb:F5H1A7	intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934|ensembl:ENSP00000356042	psi-mi:radi_human(display_long)|uniprotkb:RDX(gene name)|psi-mi:RDX(display_short)	psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658553|imex:IM-16425-380	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137710(gene)|ensembl:ENST00000645495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:1903392"(negative regulation of adherens junction organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35241|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_002897.1|refseq:NP_001247423.1|refseq:NP_001247424.1|refseq:NP_001247425.1|refseq:NP_001247421.1|refseq:NP_001247422.1|genbank_protein_gi:28436808(identity)	ensembl:ENSP00000338934|ensembl:ENSP00000356042|refseq:NP_001104547.1|refseq:NP_003370.2|ensembl:ENSG00000092820(gene)|ensembl:ENST00000337147(transcript)|ensembl:ENST00000367075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|dip:DIP-38868N|genbank_protein_gi:33869413(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:75lzbINdL0deHtiWY7IwioSh5749606	rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606	intact-crc:E655D38F4CDDECAA|rigid:18IVNAdWGJ01Au3j7Zvvr+rQoow	false	sufficient binding region:478-583..583	sufficient binding region:1-536	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15311	uniprotkb:Q15599	intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934|ensembl:ENSP00000356042	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005|intact:EBI-15579694	psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym)	psi-mi:nhrf2_human(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658587|imex:IM-16425-382	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000338934|ensembl:ENSP00000356042|refseq:NP_001104547.1|refseq:NP_003370.2|ensembl:ENSG00000092820(gene)|ensembl:ENST00000337147(transcript)|ensembl:ENST00000367075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|dip:DIP-38868N|genbank_protein_gi:33869413(identity)	refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|ensembl:ENSG00000065054(gene)|ensembl:ENST00000424542(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031197|interpro:IPR036034|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|go:"GO:0042802"(identical protein binding)|dip:DIP-29093N|genbank_protein_gi:71897228(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	intact-crc:E33B8BED90C32773|rigid:u3zITgVW293kRAabHSLKJZnSri4	false	sufficient binding region:1-536	sufficient binding region:278-337	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15311	uniprotkb:O14745	intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934|ensembl:ENSP00000356042	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym)	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658570|imex:IM-16425-381	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000338934|ensembl:ENSP00000356042|refseq:NP_001104547.1|refseq:NP_003370.2|ensembl:ENSG00000092820(gene)|ensembl:ENST00000337147(transcript)|ensembl:ENST00000367075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|dip:DIP-38868N|genbank_protein_gi:33869413(identity)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N|genbank_protein_gi:15079984(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	intact-crc:F399A76B8756B60B|rigid:vCwlIAqoDT9z9q5DCfMs2jcqfQA	false	sufficient binding region:1-536	sufficient binding region:134-358..358	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94782	uniprotkb:P15311	intact:EBI-2513396|ensembl:ENSP00000343526|ensembl:ENSP00000360188|uniprotkb:Q9UNJ3|uniprotkb:A0PJ95|uniprotkb:Q9UFR0|uniprotkb:Q59H66|uniprotkb:Q05BX7|uniprotkb:D3DQ57	intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934|ensembl:ENSP00000356042	psi-mi:ubp1_human(display_long)|uniprotkb:USP1(gene name)|psi-mi:USP1(display_short)|uniprotkb:Ubiquitin-specific-processing protease 1(gene name synonym)|uniprotkb:Deubiquitinating enzyme 1(gene name synonym)|uniprotkb:Ubiquitin thioesterase 1(gene name synonym)	psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658604|imex:IM-16425-383	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162607(gene)|ensembl:ENST00000339950(transcript)|ensembl:ENST00000371146(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0009411"(response to UV)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR033815|interpro:IPR038765|mint:O94782|rcsb pdb:6DO5|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-6783310|refseq:NP_001017415.1|refseq:NP_001017416.1|refseq:NP_003359.3|dip:DIP-53609N|genbank_protein_gi:63053520(identity)	ensembl:ENSP00000338934|ensembl:ENSP00000356042|refseq:NP_001104547.1|refseq:NP_003370.2|ensembl:ENSG00000092820(gene)|ensembl:ENST00000337147(transcript)|ensembl:ENST00000367075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|dip:DIP-38868N|genbank_protein_gi:33869413(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:cSWX5JiI+vqbREjhCJeCGAiiVzE9606	rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606	intact-crc:1E8CBD452AF437C4|rigid:hOc69suuv4obJveHtHsVKOvuVYc	false	sufficient binding region:674-785..785(IPR001394)	sufficient binding region:1-536	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969P5	uniprotkb:Q9Y2K7	intact:EBI-2932534|ensembl:ENSP00000428205|uniprotkb:A4KYM0	intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55	psi-mi:fbx32_human(display_long)|uniprotkb:FBXO32(gene name)|psi-mi:FBXO32(display_short)|uniprotkb:Muscle atrophy F-box protein(gene name synonym)|uniprotkb:Atrogin-1(gene name synonym)	psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658622|imex:IM-16425-384	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000156804(gene)|ensembl:ENST00000517956(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030018"(Z disc)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR036047|interpro:IPR040394|mint:Q969P5|reactome:R-HSA-8951664|reactome:R-HSA-9615017|reactome:R-HSA-983168|refseq:NP_478136.1|refseq:NP_001229392.1|genbank_protein_gi:22547142(identity)	ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N|genbank_protein_gi:16306579(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:c/n5Dca21NQQl96zWSf03U9nziU9606	rogid:FWcxfQykne+IrmtpDxZ218sEURc9606	intact-crc:E297043D69355859|rigid:fMDbvBTQroKJJmctgiTf6V+xekk	false	sufficient binding region:1-355	sufficient binding region:431-1162	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63208	uniprotkb:Q969P5	intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961	intact:EBI-2932534|ensembl:ENSP00000428205|uniprotkb:A4KYM0	psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym)	psi-mi:fbx32_human(display_long)|uniprotkb:FBXO32(gene name)|psi-mi:FBXO32(display_short)|uniprotkb:Muscle atrophy F-box protein(gene name synonym)|uniprotkb:Atrogin-1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658656|imex:IM-16425-386	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|genbank_protein_gi:25777712(identity)	ensembl:ENSG00000156804(gene)|ensembl:ENST00000517956(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030018"(Z disc)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR036047|interpro:IPR040394|mint:Q969P5|reactome:R-HSA-8951664|reactome:R-HSA-9615017|reactome:R-HSA-983168|refseq:NP_478136.1|refseq:NP_001229392.1|genbank_protein_gi:22547142(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606	rogid:c/n5Dca21NQQl96zWSf03U9nziU9606	intact-crc:529AC70B49823B13|rigid:FvVd7gy6PXoAB7iWhdqnRIasTBo	false	sufficient binding region:58-163(IPR001232)	sufficient binding region:1-355	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15173	uniprotkb:Q969P5	intact:EBI-3906629|uniprotkb:Q53XW6|ensembl:ENSP00000241651	intact:EBI-2932534|ensembl:ENSP00000428205|uniprotkb:A4KYM0	psi-mi:myog_human(display_long)|uniprotkb:MYOG(gene name)|psi-mi:MYOG(display_short)|uniprotkb:BHLHC3(gene name synonym)|uniprotkb:MYF4(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 3(gene name synonym)|uniprotkb:Myogenic factor 4(gene name synonym)	psi-mi:fbx32_human(display_long)|uniprotkb:FBXO32(gene name)|psi-mi:FBXO32(display_short)|uniprotkb:Muscle atrophy F-box protein(gene name synonym)|uniprotkb:Atrogin-1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658639|imex:IM-16425-385	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002470.2|ensembl:ENSG00000122180(gene)|ensembl:ENST00000241651(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009629"(response to gravity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014873"(response to muscle activity involved in regulation of muscle adaptation)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0071259"(cellular response to magnetism)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR039704|reactome:R-HSA-525793|dip:DIP-159N|genbank_protein_gi:115387121(identity)	ensembl:ENSG00000156804(gene)|ensembl:ENST00000517956(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030018"(Z disc)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR036047|interpro:IPR040394|mint:Q969P5|reactome:R-HSA-8951664|reactome:R-HSA-9615017|reactome:R-HSA-983168|refseq:NP_478136.1|refseq:NP_001229392.1|genbank_protein_gi:22547142(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:7r8zPLBvho1GRHTAr7SVXjDXRxg9606	rogid:c/n5Dca21NQQl96zWSf03U9nziU9606	intact-crc:894FF049A6E8C44D|rigid:KEK/9VLY2/4qqL8Nx5y0peehFKc	false	sufficient binding region:45-224	sufficient binding region:1-355	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13642	uniprotkb:Q02952	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	intact:EBI-2562430|intact:EBI-2680946|uniprotkb:O00310|uniprotkb:O00498|uniprotkb:Q4LE68|uniprotkb:Q5SZ80|uniprotkb:Q5TGN1|uniprotkb:Q68D82|uniprotkb:Q99970|ensembl:ENSP00000253332|ensembl:ENSP00000384537	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:aka12_human(display_long)|uniprotkb:AKAP12(gene name)|psi-mi:AKAP12(display_short)|uniprotkb:AKAP250(gene name synonym)|uniprotkb:A-kinase anchor protein 250 kDa(gene name synonym)|uniprotkb:Gravin(gene name synonym)|uniprotkb:Myasthenia gravis autoantigen(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658674|imex:IM-16425-387	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	refseq:NP_005091.2|refseq:NP_653080.1|ensembl:ENSG00000131016(gene)|ensembl:ENST00000253332(transcript)|ensembl:ENST00000402676(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061870"(positive regulation of hepatic stellate cell migration)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090036"(regulation of protein kinase C signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1900143"(positive regulation of oligodendrocyte apoptotic process)|interpro:IPR001573(Protein kinase A anchoring region)|interpro:IPR018459|interpro:IPR028540|mint:Q02952|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:XP_005267292.1|refseq:XP_016867006.1|genbank_protein_gi:21493021(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	rogid:vx4mziqb4PDChwfwSzb7mPrCn4w9606	intact-crc:161414D260C7CF64|rigid:X9SR80lwKrJN5wOAnHbwBpX1C6Y	false	sufficient binding region:3-280	sufficient binding region:1364-1782	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13642	uniprotkb:Q96JQ2	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	intact:EBI-5658691|uniprotkb:Q9H713|uniprotkb:Q9UFP4|uniprotkb:Q9HA57|uniprotkb:Q9ULN2|uniprotkb:Q9HA23|uniprotkb:B2RAR7|intact:EBI-28974156|ensembl:ENSP00000298912	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:clmn_human(display_long)|uniprotkb:Calponin-like transmembrane domain protein(gene name synonym)|uniprotkb:KIAA1188(gene name synonym)|uniprotkb:CLMN(gene name)|psi-mi:CLMN(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658702|imex:IM-16425-388	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	ensembl:ENSP00000298912|refseq:NP_079010.2|ensembl:ENSG00000165959(gene)|ensembl:ENST00000298912(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007097"(nuclear migration)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0051015"(actin filament binding)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|genbank_protein_gi:46250004(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	rogid:5680uLyZVmMQ3D5tHa3nBD2b+Hg9606	intact-crc:967595FCC0C1423D|rigid:C91Iaz3AFoyTCZxT0aBhXVJrXDA	false	sufficient binding region:3-280	sufficient binding region:368-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50461	uniprotkb:Q13642	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658724|imex:IM-16425-389	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13|genbank_protein_gi:48762935(identity)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	intact-crc:DBF96D628BDB5087|rigid:fmfXVkJSWwjpXP1w7KytwDrkHuc	false	sufficient binding region:1-194	sufficient binding region:3-280	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13642	uniprotkb:P24593	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	intact:EBI-720480|uniprotkb:Q5U0A3|ensembl:ENSP00000233813	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:ibp5_human(display_long)|uniprotkb:IGFBP5(gene name)|psi-mi:IGFBP5(display_short)|uniprotkb:IBP5(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658741|imex:IM-16425-390	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	go:"GO:0071407"(cellular response to organic cyclic compound)|refseq:NP_000590.1|dip:DIP-48433N|ensembl:ENSG00000115461(gene)|ensembl:ENST00000233813(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016942"(insulin-like growth factor binding protein complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042567"(insulin-like growth factor ternary complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0043569"(negative regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060416"(response to growth hormone)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1904205"(negative regulation of skeletal muscle hypertrophy)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012213(Insulin-like growth factor binding protein 5)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|rcsb pdb:1BOE|rcsb pdb:1H59|reactome:R-HSA-381426|reactome:R-HSA-8957275|go:"GO:1901862"(negative regulation of muscle tissue development)|genbank_protein_gi:46094066(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	rogid:NeQ0QcVrpNzyqWlmp/HvG5FIRHA9606	intact-crc:C5509EB350DD270E|rigid:/XXJru5M//8v+8xdTd7MzEb6JGk	false	sufficient binding region:3-280	sufficient binding region:130-272(IPR000716)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16363	uniprotkb:Q13642	intact:EBI-711505|uniprotkb:Q14731|uniprotkb:Q14735|uniprotkb:Q15335|uniprotkb:Q4LE44|uniprotkb:Q5SZG8|uniprotkb:Q9UE18|uniprotkb:Q9UJN9|uniprotkb:Q9BTB8	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	psi-mi:lama4_human(display_long)|uniprotkb:LAMA4(gene name)|psi-mi:LAMA4(display_short)|uniprotkb:Laminin-8 subunit alpha(gene name synonym)|uniprotkb:Laminin-9 subunit alpha(gene name synonym)|uniprotkb:Laminin-14 subunit alpha(gene name synonym)	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658759|imex:IM-16425-391	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000742(EGF-like, type 3)|refseq:NP_001098678.1|refseq:NP_001098679.1|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR001791(Laminin G)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|refseq:NP_001098676.2|refseq:NP_001098677.2|refseq:NP_002281.3|mint:Q16363|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-8874081|refseq:XP_005267040.2|refseq:XP_005267041.2|genbank_protein_gi:9845494(identity)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:oceL+X9xYGdr37L7GlsCO2BMaWQ9606	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	intact-crc:762D57553F088FFD|rigid:dKyI8CQpxQwtE3XzEmsI0S0b3hQ	false	sufficient binding region:181-1823(IPR002049)	sufficient binding region:3-280	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13642	uniprotkb:Q9UPN3-5	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	intact:EBI-6131019|intact:EBI-536284	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:q9upn3-5(display_long)|uniprotkb:MACF1(gene name)|psi-mi:MACF1(display_short)|uniprotkb:620 kDa actin-binding protein(gene name synonym)|uniprotkb:ABP620(gene name synonym)|uniprotkb:ACF7(gene name synonym)|uniprotkb:Actin cross-linking family protein 7(gene name synonym)|uniprotkb:KIAA0465(gene name synonym)|uniprotkb:KIAA1251(gene name synonym)|uniprotkb:Macrophin-1(gene name synonym)|uniprotkb:Trabeculin-alpha(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658777|imex:IM-16425-392	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	intact:EBI-522925(isoform-parent)|genbank_protein_gi:33188442(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	rogid:eXp1bnAZeqXA66p9WWkiFxW3Ttk9606	intact-crc:42A95A38CF7787EE|rigid:YHbR/6b3nSPvj+uOxnpohsMNhks	false	sufficient binding region:3-280	sufficient binding region:4861-5938(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16649	uniprotkb:Q13642	intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym)	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658813|imex:IM-16425-394	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1|genbank_protein_gi:52630428(identity)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	intact-crc:A40A3DDC2EED9C54|rigid:aU6mhHQo4NdlGcp6Cp4qL+V1GWo	false	sufficient binding region:158-462	sufficient binding region:3-280	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q00872	uniprotkb:Q13642	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658795|imex:IM-16425-393	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	intact-crc:0EB84E57AFFAF3C8|rigid:iRgq0QvrWTCjtPZDkwzo8jlOfdo	false	sufficient binding region:633-1141(IPR003961)	sufficient binding region:3-280	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13642	uniprotkb:P23759-1	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	intact:EBI-10909451|ensembl:ENSP00000364524	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:p23759-1(display_long)|uniprotkb:PAX7(gene name)|psi-mi:PAX7(display_short)|uniprotkb:HUP1(gene name synonym)|uniprotkb:HuP1(gene name synonym)|uniprotkb:Long(isoform synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658830|imex:IM-16425-395	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	intact:EBI-1042757(isoform-parent)|ensembl:ENSG00000009709(gene)|ensembl:ENST00000375375(transcript)|genbank_protein_gi:4505618(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2015/07/17	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	rogid:AtDWrJAzwk3FT4Kmg5pOstfT7WM9606	intact-crc:82861B12E4C125B6|rigid:LZpr4GPq56YQB2zsYkwuyA9P1KA	false	sufficient binding region:3-280	sufficient binding region:118-520	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53GG5	uniprotkb:Q13642	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658847|imex:IM-16425-396	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:7656882(identity)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	intact-crc:B1A358A82B177606|rigid:9sqnFTWKx6A0BkFNEWKTctVmI1w	false	sufficient binding region:123-364	sufficient binding region:3-280	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q13642	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658874|imex:IM-16425-397	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	intact-crc:DE344BE170814D9D|rigid:ZQ+17or+HVTisDt6CLk3hshIAMk	false	sufficient binding region:9003-34350	sufficient binding region:3-280	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NUA8	uniprotkb:Q13642	intact:EBI-3446805|uniprotkb:Q8N1R1|uniprotkb:Q5TFU5|uniprotkb:O75066|ensembl:ENSP00000364798|ensembl:ENSP00000384527	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	psi-mi:zbt40_human(display_long)|uniprotkb:ZBTB40(gene name)|psi-mi:ZBTB40(display_short)|uniprotkb:KIAA0478(gene name synonym)	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658891|imex:IM-16425-398	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011540801.1|refseq:NP_001077090.1|refseq:NP_055685.3|ensembl:ENSG00000184677(gene)|ensembl:ENST00000375647(transcript)|ensembl:ENST00000404138(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030282"(bone mineralization)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030404|interpro:IPR036236|genbank_protein_gi:37221179(identity)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:+/fjRyBlX7GPiMGtK3HfIySvzSw9606	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	intact-crc:1FA9D6BAC5778D2D|rigid:Wqjj/S4MDvInekNKe4Ci+mMuK/I	false	sufficient binding region:1142-1239..1239(IPR007087)	sufficient binding region:3-280	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:P42765	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-2852639|uniprotkb:Q9BUT6|ensembl:ENSP00000285093	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:thim_human(display_long)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:ACAA2(gene name)|psi-mi:ACAA2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:T1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658909|imex:IM-16425-399	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:NP_006102.2|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P42765|rcsb pdb:4C2J|rcsb pdb:4C2K|reactome:R-HSA-77289|interpro:IPR020613|ensembl:ENSG00000167315(gene)|ensembl:ENST00000285093(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|genbank_protein_gi:12804930(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:TJMFLcEB5eKz36plSuUiteAJN9g9606	intact-crc:C73F88C663BFCAE3|rigid:ZplBRVUeTA2zIUPhx24HwhnWJXI	false	sufficient binding region:1-91	sufficient binding region:25-397(IPR002155)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:P52895	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-5658927|ensembl:ENSP00000370129|uniprotkb:B4DKR9|uniprotkb:Q5SR16|uniprotkb:Q96A71|uniprotkb:Q7M4N1|uniprotkb:A8K2N9|uniprotkb:Q14133	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:ak1c2_human(display_long)|uniprotkb:3-alpha-HSD3(gene name synonym)|uniprotkb:Chlordecone reductase homolog HAKRD(gene name synonym)|uniprotkb:DDH2(gene name synonym)|uniprotkb:Dihydrodiol dehydrogenase 2(gene name synonym)|uniprotkb:Dihydrodiol dehydrogenase/bile acid-binding protein(gene name synonym)|uniprotkb:Type III 3-alpha-hydroxysteroid dehydrogenase(gene name synonym)|uniprotkb:AKR1C2(gene name)|psi-mi:AKR1C2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658936|imex:IM-16425-400	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	ensembl:ENSG00000151632(gene)|ensembl:ENST00000380753(transcript)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005829"(cytosol)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007586"(digestion)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016229"(steroid dehydrogenase activity)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0018636"(phenanthrene 9,10-monooxygenase activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032052"(bile acid binding)|go:"GO:0042448"(progesterone metabolic process)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0047023"(androsterone dehydrogenase activity)|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0047086"(ketosteroid monooxygenase activity)|go:"GO:0047115"(trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity)|go:"GO:0047718"(indanol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071395"(cellular response to jasmonic acid stimulus)|go:"GO:0071799"(cellular response to prostaglandin D stimulus)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|interpro:IPR044482|rcsb pdb:1IHI|rcsb pdb:1J96|rcsb pdb:1XJB|rcsb pdb:2HDJ|rcsb pdb:2IPJ|rcsb pdb:4JQ1|rcsb pdb:4JQ2|refseq:NP_001345.1|refseq:NP_995317.1|refseq:NP_001128713.1|rcsb pdb:4JQ3|rcsb pdb:4JQ4|rcsb pdb:4JQA|rcsb pdb:4JTQ|rcsb pdb:4JTR|rcsb pdb:4L1W|rcsb pdb:4L1X|rcsb pdb:4XO6|rcsb pdb:4XO7|reactome:R-HSA-193368|reactome:R-HSA-193775|reactome:R-HSA-193807|genbank_protein_gi:45446744(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:1Ebp59003LAdRmDRBKh3QaSkAUs9606	intact-crc:3D94520016EB6274|rigid:has+cn0n2FkAFAQlPrACiZGYNz0	false	sufficient binding region:1-91	sufficient binding region:4-323(IPR001395)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q86W74-1	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-25795145|ensembl:ENSP00000429015	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:q86w74-1(display_long)|uniprotkb:ANKRD46(gene name)|psi-mi:ANKRD46(display_short)|uniprotkb:Ankyrin repeat small protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658954|imex:IM-16425-401	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	intact:EBI-5658959(isoform-parent)|ensembl:ENSG00000186106(gene)|ensembl:ENST00000520552(transcript)|genbank_protein_gi:50053931(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2020/08/14	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:SuUAaiElEyuX49694dWl1r8Lq5c9606	intact-crc:512E90FECACC6758|rigid:VjW6mrLFtou/AMPtpsKe6FUs69I	false	sufficient binding region:1-91	sufficient binding region:202-232	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q0VGL1	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-5658976|ensembl:ENSP00000343118	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:ltor4_human(display_long)|uniprotkb:LAMTOR4(gene name)|psi-mi:LAMTOR4(display_short)|uniprotkb:C7orf59(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5658980|imex:IM-16425-402	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	dip:DIP-61481N|refseq:NP_001008396.1|refseq:XP_016867687.1|ensembl:ENSG00000188186(gene)|ensembl:ENST00000341942(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0008361"(regulation of cell size)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|interpro:IPR034601|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK5|rcsb pdb:6B9X|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|rcsb pdb:6WJ2|rcsb pdb:6WJ3|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|genbank_protein_gi:56606126(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:IByB9Q3locB7cnKrbXVbaoCgvSk9606	intact-crc:4178410F2C2F18A2|rigid:vMIZ2Qg4+Vfr7SZWSuUhfaAvyL8	false	sufficient binding region:1-91	sufficient binding region:1-99..99	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q9NZA1	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-5658997|uniprotkb:Q96JT5|uniprotkb:Q9BWZ0|uniprotkb:Q5T4Z0|uniprotkb:B3KUF1|uniprotkb:Q8NBY3|ensembl:ENSP00000185206	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:clic5_human(display_long)|uniprotkb:CLIC5(gene name)|psi-mi:CLIC5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659005|imex:IM-16425-403	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:NP_001107558.1|refseq:NP_058625.2|refseq:NP_001242952.1|refseq:XP_016866442.1|ensembl:ENSG00000112782(gene)|ensembl:ENST00000185206(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005938"(cell cortex)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006821"(chloride transport)|go:"GO:0007565"(female pregnancy)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030264|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|interpro:IPR042069|mint:Q9NZA1|rcsb pdb:6Y2H|reactome:R-HSA-9662360|reactome:R-HSA-9662361|genbank_protein_gi:82617631(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:RW5615PpvwO8iF69YkWtrnO7qOQ9606	intact-crc:2CBF9561BA2AA766|rigid:mdJUOUbxnWwxXa5qN+l0F++rjkA	false	sufficient binding region:1-91	sufficient binding region:154-410(IPR002946)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q96EY1	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659023|imex:IM-16425-404	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N|genbank_protein_gi:17066574(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606	intact-crc:8F6D015B13305A78|rigid:KLYCaEdlXZmFboZ2m5unXnEzJeE	false	sufficient binding region:1-91	sufficient binding region:287-480	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q9H8V3	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659040|imex:IM-16425-405	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N|genbank_protein_gi:21735571(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	intact-crc:BD9DA9B8858DD57F|rigid:JFG5zTbLICTyrBkI1yWOgEaGi1A	false	sufficient binding region:1-91	sufficient binding region:581-914	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:P68104	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659057|imex:IM-16425-406	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1|genbank_protein_gi:83367078(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606	intact-crc:7BEACC77D141F5C0|rigid:b2pmFX1D5Gb/HAejsj53c0zGJvo	false	sufficient binding region:1-91	sufficient binding region:220-462..462	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q14152	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659074|imex:IM-16425-407	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N|genbank_protein_gi:83367067(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	intact-crc:38490C8E4C03D4CA|rigid:odJxMI17DMQFgOdcD5MO78ix6js	false	sufficient binding region:1-91	sufficient binding region:462-1382(IPR000717)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:P23588	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659092|imex:IM-16425-408	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1|genbank_protein_gi:83722280(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606	intact-crc:C9571412638F7BFC|rigid:/kySZ5pcj+qTY5Ni7/tCXU59t0Q	false	sufficient binding region:1-91	sufficient binding region:20-611(IPR000504)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X7	uniprotkb:O43504	intact:EBI-466061|uniprotkb:Q86SS0|uniprotkb:Q9BRJ4|uniprotkb:B4DSV3|ensembl:ENSP00000225394|uniprotkb:B4DGU9	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:git1_human(display_long)|uniprotkb:GIT1(gene name)|psi-mi:GIT1(display_short)|uniprotkb:G protein-coupled receptor kinase-interactor 1(gene name synonym)|uniprotkb:GRK-interacting protein 1(gene name synonym)|uniprotkb:Cool-associated and tyrosine-phosphorylated protein 1(gene name synonym)|uniprotkb:p95-APP1(gene name synonym)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659110|imex:IM-16425-409	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001078923.1|refseq:NP_054749.2|ensembl:ENSG00000108262(gene)|ensembl:ENST00000225394(transcript)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045820"(negative regulation of glycolytic process)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|go:"GO:0046872"(metal ion binding)|interpro:IPR020683|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|go:"GO:0048666"(neuron development)|go:"GO:0061743"(motor learning)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0106015"(negative regulation of inflammatory response to wounding)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR038508|interpro:IPR001164(Arf GTPase activating protein)|mint:Q9Y2X7|interpro:IPR002110(Ankyrin)|reactome:R-HSA-3928664|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9619229|genbank_protein_gi:41393572(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9POm+EVvD4/BQh6bApnpXCAZyZo9606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:5AC5C479B76A224F|rigid:U69SxOZjsYp/pxfgMLCfiQnvfq4	false	sufficient binding region:191-761	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14161	uniprotkb:O43504	intact:EBI-1046878|uniprotkb:Q86U59|uniprotkb:Q96CI2|uniprotkb:Q9BV91|uniprotkb:Q9Y5V2|ensembl:ENSP00000347464	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:git2_human(display_long)|uniprotkb:G protein-coupled receptor kinase-interactor 2(gene name synonym)|uniprotkb:GRK-interacting protein 2(gene name synonym)|uniprotkb:Cool-interacting tyrosine-phosphorylated protein 2(gene name synonym)|uniprotkb:GIT2(gene name)|psi-mi:GIT2(display_short)|uniprotkb:KIAA0148(gene name synonym)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659127|imex:IM-16425-410	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139436(gene)|ensembl:ENST00000355312(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|interpro:IPR020683|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|refseq:NP_001128685.1|refseq:NP_001128686.1|refseq:NP_055591.2|refseq:NP_476510.1|refseq:NP_476511.1|refseq:XP_006719770.1|refseq:XP_006719772.1|refseq:NP_001317082.1|genbank_protein_gi:27886591(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Zy6G7UFDxfCVVUEHq44V37dWekw9606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:2F317DE1761B6C23|rigid:bMWqwKqWF39E8yoX6bJrcd+9pCo	false	sufficient binding region:247-759	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q9Y5Z4	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-741593|uniprotkb:Q96P57|ensembl:ENSP00000475750	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:hebp2_human(display_long)|uniprotkb:Placental protein 23(gene name synonym)|uniprotkb:Protein SOUL(gene name synonym)|uniprotkb:HEBP2(gene name)|psi-mi:HEBP2(display_short)|uniprotkb:C6orf34(gene name synonym)|uniprotkb:SOUL(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659144|imex:IM-16425-411	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:NP_055135.1|reactome:R-HSA-6798695|ensembl:ENSG00000051620(gene)|ensembl:ENST00000607197(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0020037"(heme binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006917(SOUL heme-binding protein)|interpro:IPR011256(Regulatory factor, effector, bacterial)|rcsb pdb:3R85|rcsb pdb:3R8J|rcsb pdb:3R8K|rcsb pdb:4AYZ|rcsb pdb:4B0Y|rcsb pdb:5GQQ|genbank_protein_gi:41393567(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:52hA9zxyHo7sgEePt10fBAVkPEc9606	intact-crc:FBCAB2B4EFAC5437|rigid:iMKHcn1PKsTVKG3bdWXyGLXOhVk	false	sufficient binding region:1-91	sufficient binding region:62-205..205(IPR006917)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:P38646	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659162|imex:IM-16425-412	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N|genbank_protein_gi:39812281(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	intact-crc:7F4047FF0493BF04|rigid:7NOqUF4pjnrmIzIwYhC6UrVRRRA	false	sufficient binding region:1-91	sufficient binding region:446-679	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05556	uniprotkb:O43504	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659179|imex:IM-16425-413	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191|genbank_protein_gi:19743818(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:5884B11DC9F2BA53|rigid:/b2jstDBVScZrAnxedCRuJRh/Hc	false	sufficient binding region:79-798(IPR002369)	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q86YW9	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-3957138|uniprotkb:Q96PC7|uniprotkb:Q96PC8|uniprotkb:Q9H9M5|uniprotkb:Q9HCD7|uniprotkb:Q9UI69|ensembl:ENSP00000417235	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:md12l_human(display_long)|uniprotkb:MED12L(gene name)|psi-mi:MED12L(display_short)|uniprotkb:KIAA1635(gene name synonym)|uniprotkb:TNRC11L(gene name synonym)|uniprotkb:TRALP(gene name synonym)|uniprotkb:TRALPUSH(gene name synonym)|uniprotkb:Mediator complex subunit 12-like protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated-like protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein-like(gene name synonym)|uniprotkb:PRO0314(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659214|imex:IM-16425-415	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:XP_011510692.1|refseq:NP_443728.3|ensembl:ENST00000309237|ensembl:ENSP00000310760|ensembl:ENST00000422248|ensembl:ENSP00000403308|ensembl:ENSP00000417235|ensembl:ENSG00000144893(gene)|ensembl:ENST00000474524(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016592"(mediator complex)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:Q86YW9|genbank_protein_gi:93277088(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:85LCBTAduFNnKfHO0S10ocwWXyE9606	intact-crc:BDB7A492977D76BD|rigid:FUjJzTMHFmioWfYSujq4pUZz+RA	false	sufficient binding region:1-91	sufficient binding region:105-2145	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:O60333	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|ensembl:ENSP00000366290|ensembl:ENSP00000502065|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659197|imex:IM-16425-414	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	ensembl:ENSG00000054523(gene)|ensembl:ENST00000377086(transcript)|ensembl:ENST00000676179(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N|genbank_protein_gi:41393558(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606	intact-crc:08C836895015278C|rigid:XYB5QYVVmgaw+N8axpK1DcdnZFI	false	sufficient binding region:1-91	sufficient binding region:57-1816	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q9UL63	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-1048053|uniprotkb:A4D1M8|uniprotkb:A6NG43|uniprotkb:Q9NSK4|uniprotkb:Q9NUS8|ensembl:ENSP00000323527	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:mkln1_human(display_long)|uniprotkb:MKLN1(gene name)|psi-mi:MKLN1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659231|imex:IM-16425-416	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:NP_001138826.1|refseq:NP_037387.2|ensembl:ENSG00000128585(gene)|ensembl:ENST00000352689(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001726"(ruffle)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0098794"(postsynapse)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010565(Muskelin, N-terminal)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|mint:Q9UL63|refseq:NP_001308245.1|genbank_protein_gi:46094063(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:7yT0576+rLpdpgT/cqXPEuf80/g9606	intact-crc:97EAA8E582E9E065|rigid:CSAD5WkW/YYnfQAJVmn2x5UUsc0	false	sufficient binding region:1-91	sufficient binding region:56-735(IPR006652)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q8IZD2	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-2689959|uniprotkb:Q86TI3|uniprotkb:B6ZDM3|uniprotkb:Q8IWR5|uniprotkb:B6ZDE4|uniprotkb:Q6P5Y2|uniprotkb:Q86WG0|uniprotkb:Q86W12|uniprotkb:Q8NFF8|uniprotkb:Q8IV78|uniprotkb:Q86WL2|uniprotkb:Q6T316|uniprotkb:Q9NWE7|uniprotkb:Q6PKG4|intact:EBI-2815322|uniprotkb:M4K8J3|intact:EBI-28975207|ensembl:ENSP00000257745|ensembl:ENSP00000312379	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:kmt2e_human(display_long)|uniprotkb:KMT2E(gene name)|psi-mi:KMT2E(display_short)|uniprotkb:MLL5(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 5(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659249|imex:IM-16425-417	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	ensembl:ENSP00000312379|ensembl:ENST00000334884|ensembl:ENSP00000335398|ensembl:ENST00000476671|ensembl:ENSP00000417888|ensembl:ENSP00000257745|refseq:XP_011514702.1|refseq:NP_061152.3|refseq:NP_891847.1|refseq:XP_005250550.1|ensembl:ENSG00000005483(gene)|ensembl:ENST00000257745(transcript)|ensembl:ENST00000311117(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006306"(DNA methylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035327"|go:"GO:0042119"(neutrophil activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1905437"(positive regulation of histone H3-K4 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR037955|interpro:IPR044434|rcsb pdb:2LV9|rcsb pdb:4L58|rcsb pdb:5HT6|reactome:R-HSA-3214841|reactome:R-HSA-8936459|genbank_protein_gi:91199542(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:R88sB8694YH12wYZLv4PLcpqegU9606	intact-crc:236352BBB0EC12C0|rigid:llv3FuuEfKIPjJWLDu3f2LRqPmA	false	sufficient binding region:1-91	sufficient binding region:494-1858	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:P23409	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-5659266|uniprotkb:Q53X80|uniprotkb:Q6FHI9|uniprotkb:B2R898|ensembl:ENSP00000228641	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:myf6_human(display_long)|uniprotkb:BHLHC4(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:MRF4(gene name synonym)|uniprotkb:Muscle-specific regulatory factor 4(gene name synonym)|uniprotkb:MYF6(gene name)|psi-mi:MYF6(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659273|imex:IM-16425-418	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:NP_002460.1|ensembl:ENSG00000111046(gene)|ensembl:ENST00000228641(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001756"(somitogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0060415"(muscle tissue morphogenesis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR039704|reactome:R-HSA-525793|genbank_protein_gi:4505298(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:Ph3Df1i1oDsmLD3zseAUcU9a7Pg9606	intact-crc:72252411F3A8DC0F|rigid:ngdQU0IM/OaPcKQytH6ApQYxFXA	false	sufficient binding region:1-91	sufficient binding region:107-242(IPR001092)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11055	uniprotkb:O43504	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659291|imex:IM-16425-419	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:A183D5045FB66331|rigid:iC2SuHUA5/5M1LbhVfIoVGZBaag	false	sufficient binding region:988-1940	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15173	uniprotkb:O43504	intact:EBI-3906629|uniprotkb:Q53XW6|ensembl:ENSP00000241651	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:myog_human(display_long)|uniprotkb:MYOG(gene name)|psi-mi:MYOG(display_short)|uniprotkb:BHLHC3(gene name synonym)|uniprotkb:MYF4(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 3(gene name synonym)|uniprotkb:Myogenic factor 4(gene name synonym)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659308|imex:IM-16425-420	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002470.2|ensembl:ENSG00000122180(gene)|ensembl:ENST00000241651(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009629"(response to gravity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014873"(response to muscle activity involved in regulation of muscle adaptation)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0071259"(cellular response to magnetism)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR039704|reactome:R-HSA-525793|dip:DIP-159N|genbank_protein_gi:115387121(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:7r8zPLBvho1GRHTAr7SVXjDXRxg9606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:B50870D4606B2D00|rigid:3Hy4FKRhQkS9q/4OdfJBtfa+z2M	false	sufficient binding region:95-224(IPR001092)	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86TG7	uniprotkb:O43504	intact:EBI-2858265|uniprotkb:Q9UPV1|uniprotkb:Q96A68	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:peg10_human(display_long)|uniprotkb:PEG10(gene name)|psi-mi:PEG10(display_short)|uniprotkb:EDR(gene name synonym)|uniprotkb:KIAA1051(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:MART2(gene name synonym)|uniprotkb:MEF3L1(gene name synonym)|uniprotkb:RGAG3(gene name synonym)|uniprotkb:Embryonal carcinoma differentiation-regulated protein(gene name synonym)|uniprotkb:Mammalian retrotransposon-derived protein 2(gene name synonym)|uniprotkb:Myelin expression factor 3-like protein 1(gene name synonym)|uniprotkb:Paternally expressed gene 10 protein(gene name synonym)|uniprotkb:Retrotransposon gag domain-containing protein 3(gene name synonym)|uniprotkb:Retrotransposon-derived gag-like polyprotein(gene name synonym)|uniprotkb:Ty3/Gypsy-like protein(gene name synonym)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659326|imex:IM-16425-421	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032549|interpro:IPR032567|refseq:NP_001035242.1|refseq:NP_001171890.1|refseq:NP_001171891.1|refseq:NP_055883.2|interpro:IPR021109|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|interpro:IPR043128|interpro:IPR043502|genbank_protein_gi:94421474(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wkCBsH9/PsFMwJFu/qOwZcn63D49606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:5C513B24364CA530|rigid:bmJZ6QKLVSQJsTciQAy15ijtBSU	false	sufficient binding region:518-708	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q07869	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-78615|uniprotkb:Q16241|uniprotkb:Q92486|uniprotkb:Q92689|uniprotkb:Q9Y3N1|ensembl:ENSP00000262735|ensembl:ENSP00000385246|ensembl:ENSP00000385523|uniprotkb:Q6I9S0|uniprotkb:B0G0X3	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:ppara_human(display_long)|uniprotkb:PPARA(gene name)|psi-mi:PPARA(display_short)|uniprotkb:NR1C1(gene name synonym)|uniprotkb:PPAR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group C member 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659343|imex:IM-16425-422	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:XP_005261712.1|refseq:XP_005261713.1|ensembl:ENSG00000186951(gene)|ensembl:ENST00000262735(transcript)|ensembl:ENST00000402126(transcript)|ensembl:ENST00000407236(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010876"(lipid localization)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033993"(response to lipid)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042060"(wound healing)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0045471"(response to ethanol)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|rcsb pdb:1I7G|go:"GO:0097371"(MDM2/MDM4 family protein binding)|rcsb pdb:1K7L|rcsb pdb:1KKQ|rcsb pdb:2NPA|rcsb pdb:2P54|rcsb pdb:2REW|rcsb pdb:2ZNN|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:2000191"(regulation of fatty acid transport)|go:"GO:2000272"(negative regulation of signaling receptor activity)|rcsb pdb:3ET1|rcsb pdb:3FEI|rcsb pdb:3G8I|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003076(Peroxisome proliferator-activated receptor, alpha)|rcsb pdb:3KDT|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:3KDU|interpro:IPR035500|mint:Q07869|rcsb pdb:3SP6|rcsb pdb:3VI8|rcsb pdb:4BCR|rcsb pdb:4CI4|reactome:R-HSA-1989781|rcsb pdb:5AZT|reactome:R-HSA-2151201|reactome:R-HSA-2426168|rcsb pdb:5HYK|rcsb pdb:6KAX|reactome:R-HSA-381340|rcsb pdb:6KAY|rcsb pdb:6KAZ|reactome:R-HSA-383280|rcsb pdb:6KB0|reactome:R-HSA-400206|rcsb pdb:6KB1|rcsb pdb:6KB2|rcsb pdb:6KB3|rcsb pdb:6KB4|rcsb pdb:6KB5|reactome:R-HSA-400253|reactome:R-HSA-4090294|rcsb pdb:6KB6|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6KB7|rcsb pdb:6KB8|rcsb pdb:6KB9|rcsb pdb:6KBA|rcsb pdb:6KXX|rcsb pdb:6KXY|rcsb pdb:6KYP|rcsb pdb:6L36|rcsb pdb:6L37|rcsb pdb:6L38|rcsb pdb:6L96|rcsb pdb:6LX4|rcsb pdb:6LX5|rcsb pdb:6LX6|rcsb pdb:6LX7|rcsb pdb:6LX8|rcsb pdb:6LX9|rcsb pdb:6LXA|rcsb pdb:6LXB|rcsb pdb:6LXC|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7C6Q|reactome:R-HSA-1368082|reactome:R-HSA-1368108|refseq:NP_001001928.1|refseq:NP_005027.2|refseq:XP_011528541.1|refseq:XP_011528542.1|refseq:XP_011528543.1|refseq:XP_011528544.1|refseq:XP_011528545.1|refseq:XP_006724332.1|refseq:XP_006724333.1|dip:DIP-241N|genbank_protein_gi:61744437(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:0ZZ5eL0cNC8OgOvd8spQ5ypBvAo9606	intact-crc:C1A3476E0794DBF0|rigid:MuEcAonzTGnWy+IMuWvhpdnKdzc	false	sufficient binding region:1-91	sufficient binding region:15-468(IPR000315)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23246	uniprotkb:O43504	intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659361|imex:IM-16425-423	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N|genbank_protein_gi:4826997(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:078BC03F56668FA4|rigid:6RNnZk1DCmCWv92ezkKQ/TVL6m4	false	sufficient binding region:260-707(IPR000504)	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15464	uniprotkb:O43504	intact:EBI-4402156|uniprotkb:B9EGM0|uniprotkb:D3DRQ5|uniprotkb:Q504U5|uniprotkb:Q5VUM8|ensembl:ENSP00000366936	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:shb_human(display_long)|uniprotkb:SHB(gene name)|psi-mi:SHB(display_short)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659379|imex:IM-16425-424	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003019.2|ensembl:ENSG00000107338(gene)|ensembl:ENST00000377707(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR000980(SH2 motif)|interpro:IPR035040|interpro:IPR035045|interpro:IPR036860|mint:Q15464|reactome:R-HSA-4420097|genbank_protein_gi:106879209(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DD+KZlDzdHYok9if0pI0b4yKcf49606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:4BC6A82015115EDA|rigid:6+YfPIG02Qoeiy4dlMXAvcBrhzs	false	sufficient binding region:321-509	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q13485	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-347263|uniprotkb:A8K405|ensembl:ENSP00000341551|ensembl:ENSP00000381452	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:smad4_human(display_long)|uniprotkb:SMAD4(gene name)|psi-mi:SMAD4(display_short)|uniprotkb:DPC4(gene name synonym)|uniprotkb:MADH4(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659414|imex:IM-16425-426	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	ensembl:ENSG00000141646(gene)|refseq:NP_005350.1|ensembl:ENST00000398417(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003148"(outflow tract septum morphogenesis)|ensembl:ENST00000342988(transcript)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003360"(brainstem development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|mint:Q13485|rcsb pdb:1DD1|rcsb pdb:1G88|rcsb pdb:1MR1|rcsb pdb:1U7F|rcsb pdb:1U7V|rcsb pdb:1YGS|rcsb pdb:5C4V|rcsb pdb:5MEY|rcsb pdb:5MEZ|rcsb pdb:5MF0|rcsb pdb:5UWU|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-8941326|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9615017|reactome:R-HSA-9617828|dip:DIP-31512N|genbank_protein_gi:34147555(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:mPu190hmySGV54KAtldys/IHuo89606	intact-crc:2169C9BBBFC5E73C|rigid:35HNaTN536/JtT2zTS0xcZeaQ0s	false	sufficient binding region:1-91	sufficient binding region:423-552..552	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:P63208	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659396|imex:IM-16425-425	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|genbank_protein_gi:25777712(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606	intact-crc:B86DD02F466514C5|rigid:vgrwFF3De5QdgcZDR4gUJ1uTPLU	false	sufficient binding region:1-91	sufficient binding region:97-163..163(IPR001232)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:Q9Y5X3	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-715760|uniprotkb:Q52LC4|uniprotkb:B7ZKN3|uniprotkb:Q9BWP0|uniprotkb:Q7KZN0|uniprotkb:D3DW26|ensembl:ENSP00000366988|ensembl:ENSP00000366998	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:snx5_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659431|imex:IM-16425-427	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	refseq:NP_055241.1|refseq:NP_689413.1|ensembl:ENSG00000089006(gene)|ensembl:ENST00000377759(transcript)|ensembl:ENST00000377768(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|interpro:IPR042135|mint:Q9Y5X3|rcsb pdb:1SYS|rcsb pdb:5TGH|rcsb pdb:5TGI|rcsb pdb:5TGJ|rcsb pdb:5WY2|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6N5Z|reactome:R-HSA-432722|genbank_protein_gi:23111046(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:VR2oUxQ4M2bm5zKeHQlao046QL09606	intact-crc:A81205B58EE8C882|rigid:L+Hhu4FLEiZflRxxXdP1kTYEcwc	false	sufficient binding region:1-91	sufficient binding region:1-404	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60343	uniprotkb:O43504	intact:EBI-522028|uniprotkb:A7E2X8|uniprotkb:B4DU25|uniprotkb:B4E235|uniprotkb:B6ETN8|uniprotkb:B6ETN9|uniprotkb:Q68D14|uniprotkb:Q5W0B9|ensembl:ENSP00000366863	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:tbcd4_human(display_long)|uniprotkb:Akt substrate of 160 kDa(gene name synonym)|uniprotkb:TBC1D4(gene name)|psi-mi:TBC1D4(display_short)|uniprotkb:KIAA0603(gene name synonym)|uniprotkb:AS160(gene name synonym)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659448|imex:IM-16425-428	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055647.2|ensembl:ENSG00000136111(gene)|ensembl:ENST00000377636(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031339"(negative regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|refseq:NP_001273587.1|refseq:NP_001273588.1|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021785|interpro:IPR035969|mint:O60343|rcsb pdb:3QYB|rcsb pdb:7NIX|reactome:R-HSA-1445148|genbank_protein_gi:114688045(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:AfptaRNss/0wnCrivoxs2PgxNOM9606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:65845FACEA7CBA78|rigid:V8rw4CzCVcAzySndMCoLYz0KskQ	false	sufficient binding region:360-1298	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99081	uniprotkb:O43504	intact:EBI-722877|uniprotkb:Q86VM2|ensembl:ENSP00000267811|ensembl:ENSP00000453737|uniprotkb:Q7Z3D9|uniprotkb:Q86TC1|uniprotkb:B4E1W1	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:htf4_human(display_long)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659482|imex:IM-16425-430	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001309086.1|refseq:NP_003196.1|refseq:NP_996919.1|refseq:NP_996920.1|refseq:NP_996921.1|refseq:NP_996923.1|ensembl:ENSG00000140262(gene)|ensembl:ENST00000267811(transcript)|ensembl:ENST00000557843(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001309080.1|refseq:NP_001293149.1|refseq:NP_001309088.1|refseq:NP_001309091.1|refseq:NP_001309094.1|dip:DIP-29403N|mint:Q99081|rcsb pdb:2KNH|rcsb pdb:4JOL|reactome:R-HSA-525793|reactome:R-HSA-8939236|reactome:R-HSA-9031628|genbank_protein_gi:46370078(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:XnBrmDaoz2JZQ66PCjfJsmaQ6209606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:97BC20E39378C55D|rigid:otSRHi0O0Mo9ZYv+mFCUl1Knvlk	false	sufficient binding region:237-682(IPR001092)	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43504	uniprotkb:O15273	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659465|imex:IM-16425-429	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:BA9905512DA6CA92|rigid:TMrD/J6j+ZrhogQ9gqRt/BZdiZo	false	sufficient binding region:1-91	sufficient binding region:4-167..167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q05516	uniprotkb:O43504	intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659500|imex:IM-16425-431	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N|genbank_protein_gi:66932930(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:CA2DF92ADAF55EBE|rigid:Np+EkrThDMr1FUQD1VxzP1y7Dyc	false	sufficient binding region:413-673	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92610	uniprotkb:O43504	intact:EBI-1210420|uniprotkb:Q2M1T2|uniprotkb:Q504Y9|ensembl:ENSP00000299927|ensembl:ENSP00000452877	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:zn592_human(display_long)|uniprotkb:ZNF592(gene name)|psi-mi:ZNF592(display_short)|uniprotkb:KIAA0211(gene name synonym)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659517|imex:IM-16425-432	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520548.1|refseq:XP_011520549.1|refseq:XP_005255053.1|refseq:NP_055445.2|refseq:XP_016878223.1|ensembl:ENSG00000166716(gene)|ensembl:ENST00000299927(transcript)|ensembl:ENST00000560079(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041697|genbank_protein_gi:108860696(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38788352(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:eElXHEWfzjVaiLf6Ns2u5SBqhKs9606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:400CD6E3DD8FA0AC|rigid:tVZZjgn5DPmi4qbn8opuFnuyBLA	false	sufficient binding region:821-1267	sufficient binding region:1-91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12982	uniprotkb:P08107	intact:EBI-752094|uniprotkb:B4DS94|ensembl:ENSP00000475320|ensembl:ENSP00000267859|ensembl:ENSP00000412767	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:bnip2_human(display_long)|uniprotkb:BNIP2(gene name)|psi-mi:BNIP2(display_short)|uniprotkb:NIP2(gene name synonym)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659534|imex:IM-16425-433	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004321.2|refseq:NP_001307604.1|ensembl:ENST00000267859(transcript)|ensembl:ENST00000415213(transcript)|ensembl:ENST00000607373(transcript)|go:"GO:0004309"(exopolyphosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006798"(polyphosphate catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000140299(gene)|interpro:IPR036865|reactome:R-HSA-525793|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090649"(response to oxygen-glucose deprivation)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR022181|genbank_protein_gi:558843(identity)	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|genbank_protein_gi:26787974(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:A/xI0cdQ50bAIX/e5AQAyWeUqjs9606	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:10513887A7314FC5|rigid:UCvuZh8FFfHgtv78mqSSIMDXy9A	false	sufficient binding region:1-314	sufficient binding region:1-641	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08107	uniprotkb:Q9UNN5	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	intact:EBI-718246|uniprotkb:Q9UF34|uniprotkb:Q9UNT3|uniprotkb:Q9Y2Z3|uniprotkb:Q549F0|ensembl:ENSP00000379457	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:faf1_human(display_long)|uniprotkb:FAF1(gene name)|psi-mi:FAF1(display_short)|uniprotkb:CGI-03(orf name)|uniprotkb:UBXD12(gene name synonym)|uniprotkb:UBXN3A(gene name synonym)|uniprotkb:UBX domain-containing protein 3A(gene name synonym)|uniprotkb:UBX domain-containing protein 12(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659551|imex:IM-16425-434	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|genbank_protein_gi:26787974(identity)	refseq:NP_008982.1|ensembl:ENSP00000379457|ensembl:ENSG00000185104(gene)|ensembl:ENST00000396153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008219"(cell death)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR033043|interpro:IPR036249|interpro:IPR044541|rcsb pdb:1H8C|rcsb pdb:2DZM|rcsb pdb:2EC4|rcsb pdb:3E21|rcsb pdb:3QC8|rcsb pdb:3QCA|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3QX1|rcsb pdb:3R3M|go:"GO:0031072"(heat shock protein binding)|dip:DIP-38245N|genbank_protein_gi:19528653(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	rogid:jYlrz7+swvye+qZ/6F4yTv74wLI9606	intact-crc:F2CAEE3384A24AD1|rigid:ToZFKTMLDs9Ur8dKsslaqDp37bs	false	sufficient binding region:1-641	sufficient binding region:13-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:P08107	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659568|imex:IM-16425-435	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|genbank_protein_gi:26787974(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:CAC9790B7B4E79FF|rigid:7nUy1fGGrwHCnUn2ITKAgQKQYA8	false	sufficient binding region:511-1141(IPR000941)	sufficient binding region:1-641	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08107	uniprotkb:P50502	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	intact:EBI-357285|ensembl:ENSP00000216218|uniprotkb:O14999|uniprotkb:Q2TU77	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:f10a1_human(display_long)|uniprotkb:ST13(gene name)|psi-mi:ST13(display_short)|uniprotkb:HIP(gene name synonym)|uniprotkb:SNC6(gene name synonym)|uniprotkb:AAG2(gene name synonym)|uniprotkb:Aging-associated protein 2(gene name synonym)|uniprotkb:FAM10A1(gene name synonym)|uniprotkb:Suppression of tumorigenicity 13 protein(gene name synonym)|uniprotkb:Putative tumor suppressor ST13(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:Progesterone receptor-associated p48 protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-33(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659586|imex:IM-16425-436	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|genbank_protein_gi:26787974(identity)	ensembl:ENSG00000100380(gene)|ensembl:ENST00000216218(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|mint:P50502|rcsb pdb:1UZS|reactome:R-HSA-3371453|refseq:NP_003923.2|genbank_protein_gi:21237722(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	rogid:yqG5t4Kuj7ZzfNwlJzGZYscKiM89606	intact-crc:5A0387088BF4B403|rigid:UJihFyaRrz/wKt9Bh5VYxPfU9yA	false	sufficient binding region:1-641	sufficient binding region:100-369	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08107	uniprotkb:P31948	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	intact:EBI-1054052|uniprotkb:Q5TZU9|intact:EBI-4404694|uniprotkb:B4DM70|uniprotkb:F5H0T1|uniprotkb:G3XAD8|uniprotkb:Q3ZCU9|ensembl:ENSP00000305958	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:stip1_human(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:STIP1(gene name)|psi-mi:STIP1(display_short)|uniprotkb:Transformation-sensitive protein IEF SSP 3521(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-11(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659603|imex:IM-16425-437	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|genbank_protein_gi:26787974(identity)	refseq:NP_006810.1|ensembl:ENSG00000168439(gene)|ensembl:ENST00000305218(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR041243|mint:P31948|rcsb pdb:1ELR|rcsb pdb:1ELW|rcsb pdb:2LNI|rcsb pdb:2NC9|rcsb pdb:3ESK|rcsb pdb:3FWV|reactome:R-HSA-3371497|reactome:R-HSA-9696273|refseq:NP_001269581.1|refseq:NP_001269582.1|dip:DIP-41085N|genbank_protein_gi:110225356(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	rogid:/encEzabIj7I9YdYaYY2UvRG3Pg9606	intact-crc:78E9096E5DD84DF6|rigid:zOJqBaUaVD6khsjiI1xLrJHCr4U	false	sufficient binding region:1-641	sufficient binding region:22-543(IPR001440)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94826	uniprotkb:P08107	intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659622|imex:IM-16425-438	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020|genbank_protein_gi:54607134(identity)	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|genbank_protein_gi:26787974(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:018313C34CE91465|rigid:2hiIAT3SfkWpar6+A8mw4t7O49s	false	sufficient binding region:106-608(IPR001440)	sufficient binding region:1-641	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00635	uniprotkb:P08107	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659640|imex:IM-16425-439	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300|genbank_protein_gi:24497622(identity)	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|genbank_protein_gi:26787974(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:502EAFCDD5057B58|rigid:ZPD07CYfQSo61mvcR4zJ+6nWxvU	false	sufficient binding region:140-465..465(IPR003879)	sufficient binding region:1-641	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14713	uniprotkb:O60443	intact:EBI-2127319|uniprotkb:O14714|uniprotkb:D6W4Y9|uniprotkb:Q53RS0|ensembl:ENSP00000347504|ensembl:ENSP00000353850	intact:EBI-719315|uniprotkb:O14590|uniprotkb:Q08AQ8|uniprotkb:Q9UBV3|uniprotkb:B2RAX9|uniprotkb:A4D156|ensembl:ENSP00000339587|ensembl:ENSP00000494186|uniprotkb:B3KT05	psi-mi:itbp1_human(display_long)|uniprotkb:ITGB1BP1(gene name)|psi-mi:ITGB1BP1(display_short)|uniprotkb:ICAP1(gene name synonym)|uniprotkb:Integrin cytoplasmic domain-associated protein 1(gene name synonym)	psi-mi:gsdme_human(display_long)|uniprotkb:GSDME(gene name)|psi-mi:GSDME(display_short)|uniprotkb:DFNA5(gene name synonym)|uniprotkb:ICERE1(gene name synonym)|uniprotkb:Inversely correlated with estrogen receptor expression 1(gene name synonym)|uniprotkb:Non-syndromic hearing impairment protein 5(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659658|imex:IM-16425-440	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508718.1|refseq:NP_004754.1|refseq:NP_071729.1|refseq:XP_016860758.1|refseq:XP_016860759.1|refseq:XP_016860756.1|refseq:XP_016860757.1|refseq:NP_001305995.1|refseq:NP_001305996.1|refseq:NP_001305997.1|refseq:XP_006711966.1|refseq:XP_005246240.1|refseq:XP_005246241.1|refseq:XP_005246242.1|refseq:XP_005246246.1|ensembl:ENSG00000119185(gene)|ensembl:ENST00000355346(transcript)|ensembl:ENST00000360635(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002043"(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033622"(integrin activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035148"(tube formation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051451"(myoblast migration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:2001044"(regulation of integrin-mediated signaling pathway)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR019517|rcsb pdb:1K11|rcsb pdb:4DX8|rcsb pdb:4DX9|rcsb pdb:4JIF|genbank_protein_gi:20143950(identity)	refseq:NP_001120925.1|refseq:NP_001120926.1|refseq:NP_004394.1|ensembl:ENSG00000105928(gene)|ensembl:ENST00000342947(transcript)|ensembl:ENST00000645220(transcript)|go:"GO:0002839"(positive regulation of immune response to tumor cell)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022829"(wide pore channel activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0070265"(necrotic cell death)|go:"GO:0070269"(pyroptosis)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1901612"(cardiolipin binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR040460|interpro:IPR041263|interpro:IPR042377|reactome:R-HSA-111457|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-9710421|refseq:XP_016867291.1|genbank_protein_gi:116734721(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:QxRmizA77Dvcwg8rkqt1bt3sI2U9606	rogid:1kUobH3l3u6LRc7dyMBlMsZvVBg9606	intact-crc:B693774B776CF0A9|rigid:Evsb50OwZjSizVVKkBfnfq3aSlE	false	sufficient binding region:48-200	sufficient binding region:1-496(IPR007677)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14713	uniprotkb:Q8WV83	intact:EBI-2127319|uniprotkb:O14714|uniprotkb:D6W4Y9|uniprotkb:Q53RS0|ensembl:ENSP00000347504|ensembl:ENSP00000353850	intact:EBI-5659681|uniprotkb:Q9H6P8|uniprotkb:Q9H7D8|ensembl:ENSP00000245680	psi-mi:itbp1_human(display_long)|uniprotkb:ITGB1BP1(gene name)|psi-mi:ITGB1BP1(display_short)|uniprotkb:ICAP1(gene name synonym)|uniprotkb:Integrin cytoplasmic domain-associated protein 1(gene name synonym)	psi-mi:s35f5_human(display_long)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 3(gene name synonym)|uniprotkb:NS5ATP3(gene name synonym)|uniprotkb:UNQ2545/PRO6097(orf name)|uniprotkb:SLC35F5(gene name)|psi-mi:SLC35F5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659676|imex:IM-16425-441	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508718.1|refseq:NP_004754.1|refseq:NP_071729.1|refseq:XP_016860758.1|refseq:XP_016860759.1|refseq:XP_016860756.1|refseq:XP_016860757.1|refseq:NP_001305995.1|refseq:NP_001305996.1|refseq:NP_001305997.1|refseq:XP_006711966.1|refseq:XP_005246240.1|refseq:XP_005246241.1|refseq:XP_005246242.1|refseq:XP_005246246.1|ensembl:ENSG00000119185(gene)|ensembl:ENST00000355346(transcript)|ensembl:ENST00000360635(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002043"(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033622"(integrin activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035148"(tube formation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051451"(myoblast migration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:2001044"(regulation of integrin-mediated signaling pathway)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR019517|rcsb pdb:1K11|rcsb pdb:4DX8|rcsb pdb:4DX9|rcsb pdb:4JIF|genbank_protein_gi:20143950(identity)	refseq:NP_079457.2|refseq:NP_001317246.1|ensembl:ENSG00000115084(gene)|ensembl:ENST00000245680(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|genbank_protein_gi:21361958(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:QxRmizA77Dvcwg8rkqt1bt3sI2U9606	rogid:Pnbf2MAHV+iqSJKaIf+na8AKXMg9606	intact-crc:BEA6E13DE0AE56E3|rigid:s8Xw0+TJWPBf8uumKFV3BInby+Y	false	sufficient binding region:48-200	sufficient binding region:468-523..523	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46939	uniprotkb:O14713	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	intact:EBI-2127319|uniprotkb:O14714|uniprotkb:D6W4Y9|uniprotkb:Q53RS0|ensembl:ENSP00000347504|ensembl:ENSP00000353850	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:itbp1_human(display_long)|uniprotkb:ITGB1BP1(gene name)|psi-mi:ITGB1BP1(display_short)|uniprotkb:ICAP1(gene name synonym)|uniprotkb:Integrin cytoplasmic domain-associated protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659699|imex:IM-16425-442	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665|genbank_protein_gi:110611227(identity)	refseq:XP_011508718.1|refseq:NP_004754.1|refseq:NP_071729.1|refseq:XP_016860758.1|refseq:XP_016860759.1|refseq:XP_016860756.1|refseq:XP_016860757.1|refseq:NP_001305995.1|refseq:NP_001305996.1|refseq:NP_001305997.1|refseq:XP_006711966.1|refseq:XP_005246240.1|refseq:XP_005246241.1|refseq:XP_005246242.1|refseq:XP_005246246.1|ensembl:ENSG00000119185(gene)|ensembl:ENST00000355346(transcript)|ensembl:ENST00000360635(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002043"(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033622"(integrin activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035148"(tube formation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051451"(myoblast migration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:2001044"(regulation of integrin-mediated signaling pathway)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR019517|rcsb pdb:1K11|rcsb pdb:4DX8|rcsb pdb:4DX9|rcsb pdb:4JIF|genbank_protein_gi:20143950(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rogid:QxRmizA77Dvcwg8rkqt1bt3sI2U9606	intact-crc:EBF8349C2D4C6203|rigid:g/HYrPb9mOTz3VXMGUvTYzuBW6Y	false	sufficient binding region:1304-3433(IPR002017)	sufficient binding region:48-200	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKP3	uniprotkb:P07900	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659722|imex:IM-16425-443	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N|genbank_protein_gi:63029936(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	intact-crc:46DF3DC028F40853|rigid:Ue8nnAHBobpFR5texCnmY7cH9JI	false	sufficient binding region:1-347	sufficient binding region:159-732(IPR001404)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08238	uniprotkb:Q9UKP3	intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym)	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659740|imex:IM-16425-444	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N|genbank_protein_gi:20149593(identity)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wOsW7C10v2oMsM+REE38K6PAan09606	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	intact-crc:8DC2664415406CAB|rigid:5Y8GrR4V/K4TpFdI2GdzFNtCwiA	false	sufficient binding region:25-724(IPR001404)	sufficient binding region:1-347	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15397	uniprotkb:Q9UKP3	intact:EBI-725523|uniprotkb:Q547G7|uniprotkb:Q5SZY9|uniprotkb:Q6IB47|uniprotkb:Q96B27|uniprotkb:Q96L78|uniprotkb:Q96L79|uniprotkb:Q96L80|uniprotkb:A8K804|ensembl:ENSP00000380982	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	psi-mi:pum3_human(display_long)|uniprotkb:PUM3(gene name)|psi-mi:PUM3(display_short)|uniprotkb:cPERP-C(gene name synonym)|uniprotkb:HBV X-transactivated gene 5 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 5(gene name synonym)|uniprotkb:KIAA0020(gene name synonym)|uniprotkb:Minor histocompatibility antigen HA-8(gene name synonym)|uniprotkb:PUF-A(gene name synonym)|uniprotkb:XTP5(gene name synonym)	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659758|imex:IM-16425-445	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055693.4|ensembl:ENSG00000080608(gene)|ensembl:ENST00000397885(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006417"(regulation of translation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012959(CPL)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR040059|mint:Q15397|rcsb pdb:4WZR|rcsb pdb:4WZW|genbank_protein_gi:109948282(identity)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:CjfVWg+3P3ai0EiHgeH8usbvgxg9606	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	intact-crc:8446AA517F3F2704|rigid:hsVsI579Pbze+dv9KUKXYl1SWx0	false	sufficient binding region:101-648(IPR001313)	sufficient binding region:1-347	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NEY8	uniprotkb:Q9UKP3	intact:EBI-474076|uniprotkb:Q86YT2|uniprotkb:Q8IXN3|uniprotkb:Q8TB09|uniprotkb:Q96NB9|uniprotkb:Q9NXL4|uniprotkb:Q9P0P6|uniprotkb:Q9P0R9|uniprotkb:E9PAX8|ensembl:ENSP00000378935|ensembl:ENSP00000479913	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	psi-mi:pphln_human(display_long)|uniprotkb:Gastric cancer antigen Ga50(gene name synonym)|uniprotkb:HSPC206(orf name)|uniprotkb:HSPC232(orf name)|uniprotkb:PPHLN1(gene name)|psi-mi:PPHLN1(display_short)|uniprotkb:CDC7 expression repressor(gene name synonym)	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659776|imex:IM-16425-446	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137259.1|refseq:NP_001137260.1|refseq:NP_057572.5|refseq:NP_958846.1|refseq:NP_958847.1|refseq:NP_958848.1|refseq:NP_958923.1|dip:DIP-49051N|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031424"(keratinization)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR028851|mint:Q8NEY8|rcsb pdb:6SWG|ensembl:ENSG00000134283(gene)|ensembl:ENST00000395568(transcript)|ensembl:ENST00000610488(transcript)|genbank_protein_gi:41872348(identity)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:+s8KstGQ7d91qe3DDnpKYMJon7o9606	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	intact-crc:39A672CAF8388A58|rigid:2pPJEClgGQC1Ok25Zw0x4akPauc	false	sufficient binding region:94-458	sufficient binding region:1-347	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKP3	uniprotkb:Q9Y371	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659793|imex:IM-16425-447	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:14727126(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	intact-crc:7E05EFDAE871840A|rigid:mwFwgzMB9e7w2SjvGHFPDOCUL8s	false	sufficient binding region:1-347	sufficient binding region:142-365(IPR004148)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKP3	uniprotkb:P29401	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	intact:EBI-1050560|uniprotkb:Q8TBA3|uniprotkb:Q96HH3|uniprotkb:A8K089|uniprotkb:B4DE31|uniprotkb:E7EPA7|ensembl:ENSP00000405455|ensembl:ENSP00000417773|intact:EBI-11110174	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:tkt_human(display_long)|uniprotkb:TKT(gene name)|psi-mi:TKT(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659828|imex:IM-16425-449	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	refseq:NP_001055.1|refseq:NP_001128527.1|refseq:NP_001244957.1|ensembl:ENSG00000163931(gene)|ensembl:ENST00000423525(transcript)|ensembl:ENST00000462138(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004802"(transketolase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0016604"(nuclear body)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031982"(vesicle)|go:"GO:0040008"(regulation of growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|mint:P29401|rcsb pdb:3MOS|rcsb pdb:3OOY|rcsb pdb:4KXU|rcsb pdb:4KXV|rcsb pdb:4KXW|rcsb pdb:4KXX|rcsb pdb:4KXY|rcsb pdb:6HA3|rcsb pdb:6HAD|rcsb pdb:6RJB|reactome:R-HSA-163754|reactome:R-HSA-71336|refseq:XP_011532356.1|genbank_protein_gi:388890(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	rogid:Z3Ad5GdEd0rFCT9uHv85N+2KAAY9606	intact-crc:98BB0DE82618C3DF|rigid:Wxn5TGsyb5ISRAoxq7A0THq5FDA	false	sufficient binding region:1-347	sufficient binding region:87-623(IPR005474)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKP3	uniprotkb:Q8N3U4	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659811|imex:IM-16425-448	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N|genbank_protein_gi:112789533(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	rogid:sJ813DVkungq+1f1rgugDN2gsn09606	intact-crc:4B6742DAAC45666A|rigid:8hAMbFOxRELmb4A3dDAg0xJhthE	false	sufficient binding region:1-347	sufficient binding region:55-1231	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKP3	uniprotkb:Q8WZ42	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659846|imex:IM-16425-450	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:FEE8232388BA9120|rigid:43ntLu8xb76RkyZae7euBJRlNvI	false	sufficient binding region:1-347	sufficient binding region:32276-34350(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKP3	uniprotkb:O60701	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	intact:EBI-353006|uniprotkb:O60589|uniprotkb:B3KUU2|uniprotkb:B4DN25|ensembl:ENSP00000319501|ensembl:ENSP00000421757	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:ugdh_human(display_long)|uniprotkb:UGDH(gene name)|psi-mi:UGDH(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659864|imex:IM-16425-451	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	refseq:NP_001171629.1|refseq:NP_001171630.1|refseq:NP_003350.1|ensembl:ENSG00000109814(gene)|ensembl:ENST00000316423(transcript)|ensembl:ENST00000506179(transcript)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|mint:O60701|rcsb pdb:2Q3E|rcsb pdb:2QG4|rcsb pdb:3ITK|rcsb pdb:3KHU|rcsb pdb:3PRJ|rcsb pdb:3PTZ|rcsb pdb:3TDK|rcsb pdb:3TF5|rcsb pdb:4EDF|rcsb pdb:4RJT|rcsb pdb:5TJH|rcsb pdb:5VR8|rcsb pdb:5W4X|rcsb pdb:6C4J|rcsb pdb:6C4K|rcsb pdb:6C58|rcsb pdb:6C5A|rcsb pdb:6C5Z|reactome:R-HSA-173599|genbank_protein_gi:63053519(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	rogid:FB1nDJFtfQk18OPze1TyR998SNk9606	intact-crc:7856C48F9254633B|rigid:9jtTWkoyKRMTayENMre8ROwHQiw	false	sufficient binding region:1-347	sufficient binding region:170-494(IPR001732)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:Q9UKP3	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659882|imex:IM-16425-452	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|genbank_protein_gi:33946268(identity)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	intact-crc:07CAD32011FBD4DF|rigid:k1+hz0fm0cOWjR0Gg0je63H5UX4	false	sufficient binding region:1-505	sufficient binding region:1-347	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37268	uniprotkb:P18084	intact:EBI-714550|intact:EBI-1058542|uniprotkb:Q96GT0|ensembl:ENSP00000220584|ensembl:ENSP00000480828|ensembl:ENSP00000481481|uniprotkb:B3KQ95|uniprotkb:B4DJE5|uniprotkb:B4DT56|uniprotkb:B7Z1J3	intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181	psi-mi:fdft_human(display_long)|uniprotkb:Farnesyl-diphosphate farnesyltransferase(gene name synonym)|uniprotkb:"FPP:FPP farnesyltransferase"(gene name synonym)|uniprotkb:FDFT1(gene name)|psi-mi:FDFT1(display_short)|uniprotkb:Farnesyl-diphosphate farnesyltransferase 1(gene name synonym)	psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659899|imex:IM-16425-453	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000618539(transcript)|refseq:NP_004453.3|ensembl:ENSG00000079459(gene)|ensembl:ENST00000220584(transcript)|ensembl:ENST00000615631(transcript)|rcsb pdb:3LEE|rcsb pdb:3Q2Z|rcsb pdb:3Q30|rcsb pdb:3V66|rcsb pdb:3VJ8|rcsb pdb:3VJ9|rcsb pdb:3VJA|rcsb pdb:3VJB|rcsb pdb:3VJC|rcsb pdb:3WC9|rcsb pdb:3WCD|rcsb pdb:3WCF|rcsb pdb:3WCH|rcsb pdb:3WCI|rcsb pdb:3WCJ|rcsb pdb:3WCL|rcsb pdb:3WCM|rcsb pdb:3WEF|rcsb pdb:3WEG|rcsb pdb:3WEH|rcsb pdb:3WEI|rcsb pdb:3WEJ|rcsb pdb:3WEK|rcsb pdb:3WSA|rcsb pdb:6PYJ|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|rcsb pdb:3ASX|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0004310"(farnesyl-diphosphate farnesyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045338"(farnesyl diphosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051996"(squalene synthase activity)|interpro:IPR002060(Squalene/phytoene synthase)|interpro:IPR006449(Farnesyl-diphosphate farnesyltransferase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR019845|interpro:IPR033904|interpro:IPR044844|mint:P37268|rcsb pdb:1EZF|refseq:NP_001274671.1|refseq:NP_001274672.1|refseq:NP_001274673.1|refseq:NP_001274674.1|refseq:NP_001274676.1|refseq:NP_001274677.1|refseq:NP_001274678.1|refseq:NP_001274679.1|refseq:NP_001274680.1|refseq:NP_001274685.1|refseq:XP_016868706.1|genbank_protein_gi:292509(identity)	refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355|genbank_protein_gi:33869594(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3TjanjXw3X58/ZOEsB1xczV0/qQ9606	rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606	intact-crc:55BD0E3C6030B892|rigid:ncAV5JxR+ygXNMoX05aFhLAedQE	false	sufficient binding region:31-417(IPR006449)	sufficient binding region:743-799	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04406	uniprotkb:P18084	intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070	intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181	psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659917|imex:IM-16425-454	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism)|genbank_protein_gi:83641890(identity)	refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355|genbank_protein_gi:33869594(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606	rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606	intact-crc:FC1B87827583D496|rigid:aAOjbOcph8cgEpmuFJzCVDUPDeE	false	sufficient binding region:4-335(IPR006424)	sufficient binding region:743-799	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P18084	uniprotkb:Q3T8J9	intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181	intact:EBI-5659940|uniprotkb:Q5W0D5|uniprotkb:Q6P1Q6|uniprotkb:Q14C93|uniprotkb:Q6AWA6|uniprotkb:Q9HCG6|uniprotkb:Q9BQI1|uniprotkb:Q8IY79|uniprotkb:Q7Z3L3|uniprotkb:B7ZBL4|uniprotkb:Q5VYZ5|uniprotkb:Q3T8J8|ensembl:ENSP00000357315|ensembl:ENSP00000483100	psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short)	psi-mi:gon4l_human(display_long)|uniprotkb:GON-4 homolog(gene name synonym)|uniprotkb:GON4(gene name synonym)|uniprotkb:KIAA1606(gene name synonym)|uniprotkb:GON4L(gene name)|psi-mi:GON4L(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659935|imex:IM-16425-455	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355|genbank_protein_gi:33869594(identity)	refseq:NP_001269785.1|refseq:NP_001269787.1|refseq:NP_001269789.1|refseq:NP_001269790.1|refseq:NP_115668.4|refseq:XP_006711456.1|refseq:XP_006711457.1|ensembl:ENSG00000116580(gene)|ensembl:ENST00000368331(transcript)|ensembl:ENST00000615926(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016604"(nuclear body)|go:"GO:0030183"(B cell differentiation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033277|interpro:IPR036600|mint:Q3T8J9|genbank_protein_gi:82830423(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606	rogid:nsGw7j7o2mxnXWd4kboGgCxSCDc9606	intact-crc:05A692B3C404ECBC|rigid:ejxU+zMqY15D1ttaiFxdFWuLbRs	false	sufficient binding region:743-799	sufficient binding region:1446-2241(IPR003822)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:P18084	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659970|imex:IM-16425-456	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355|genbank_protein_gi:33869594(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606	intact-crc:C18EBDC4B9B1BDB8|rigid:Wtx8vnefbu8wwzwxZXTrZEZN+MU	false	sufficient binding region:546-1141(IPR003599)	sufficient binding region:743-799	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P18084	uniprotkb:P21675	intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short)	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5659989|imex:IM-16425-457	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355|genbank_protein_gi:33869594(identity)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N|genbank_protein_gi:20357587(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	intact-crc:DAD0A4D77440D8D1|rigid:Qm4BCd8XVSjpPxL+wtlZfxGX0nU	false	sufficient binding region:743-799	sufficient binding region:1047-1872..1872	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P18084	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660006|imex:IM-16425-458	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355|genbank_protein_gi:33869594(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606	intact-crc:C800044CE3E44ADC|rigid:D7NmHf670Tv0cQ/GXMH0mo+mi9k	false	sufficient binding region:33338-34350(IPR007110)	sufficient binding region:743-799	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HDC5	uniprotkb:Q9HDC5	intact:EBI-465137|ensembl:ENSP00000344488|uniprotkb:B2RTZ0	intact:EBI-465137|ensembl:ENSP00000344488|uniprotkb:B2RTZ0	psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym)	psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660024|imex:IM-16425-459	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104369(gene)|ensembl:ENST00000342232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060402"(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|refseq:NP_065698.1|refseq:NP_001304759.1|refseq:XP_005251331.1|refseq:XP_005251332.1|genbank_protein_gi:61676191(identity)	ensembl:ENSG00000104369(gene)|ensembl:ENST00000342232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060402"(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|refseq:NP_065698.1|refseq:NP_001304759.1|refseq:XP_005251331.1|refseq:XP_005251332.1|genbank_protein_gi:61676191(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606	rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606	intact-crc:BB5EEB5894F1E1DB|rigid:f6qv/vlyJ7yzN87yTTc2Lgq+Iw8	false	sufficient binding region:1-638	sufficient binding region:195-661(IPR003409)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HDC5	uniprotkb:Q8WZ42	intact:EBI-465137|ensembl:ENSP00000344488|uniprotkb:B2RTZ0	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660042|imex:IM-16425-460	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104369(gene)|ensembl:ENST00000342232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060402"(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|refseq:NP_065698.1|refseq:NP_001304759.1|refseq:XP_005251331.1|refseq:XP_005251332.1|genbank_protein_gi:61676191(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349720(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:263E7BDE8843D7AC|rigid:Sc1T9DNrFLw6K+16tcXx63mwj1w	false	sufficient binding region:1-638	sufficient binding region:5499-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HDC5	uniprotkb:Q9BZF9	intact:EBI-465137|ensembl:ENSP00000344488|uniprotkb:B2RTZ0	intact:EBI-350510|uniprotkb:Q14DD3|uniprotkb:Q8N3B8|uniprotkb:Q9HCL1|uniprotkb:Q9NWC6|uniprotkb:G3XAG2|uniprotkb:Q96NH6|intact:EBI-10977773|ensembl:ENSP00000314556	psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym)	psi-mi:uaca_human(display_long)|uniprotkb:UACA(gene name)|psi-mi:UACA(display_short)|uniprotkb:KIAA1561(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660060|imex:IM-16425-461	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104369(gene)|ensembl:ENST00000342232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060402"(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|refseq:NP_065698.1|refseq:NP_001304759.1|refseq:XP_005251331.1|refseq:XP_005251332.1|genbank_protein_gi:61676191(identity)	refseq:NP_001008225.1|refseq:NP_060473.2|dip:DIP-33117N|ensembl:ENSG00000137831(gene)|ensembl:ENST00000322954(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030227|interpro:IPR036770|mint:Q9BZF9|reactome:R-HSA-9013407|reactome:R-HSA-9627069|genbank_protein_gi:59850761(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606	rogid:F58VkGk2DBsUUrB+wgknUFZhJ+E9606	intact-crc:9BB2C902E5084D56|rigid:c3UFs+6VDx4SjraG3Fwc2RqVohc	false	sufficient binding region:1-638	sufficient binding region:393-1416	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60662	uniprotkb:Q00872	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660077|imex:IM-16425-462	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:CFDFA56FA5DA3830|rigid:HcsY4AvWWN9/IjVRQAgXL9NSTgA	false	sufficient binding region:1-606	sufficient binding region:16-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60662	uniprotkb:P20929-4	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-9531519|ensembl:ENSP00000386259	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:p20929-4(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660094|imex:IM-16425-463	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	ensembl:ENSG00000183091(gene)|ensembl:ENST00000409198(transcript)|intact:EBI-1049657(isoform-parent)|genbank_protein_gi:1205988(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:aoHCLWV+j7ubdhBsylj1KjSUzwA9606	intact-crc:43FC8558ABC884AC|rigid:t/1XHrzfny+Z0U1sIA0+ZHfL5Ik	false	sufficient binding region:1-606	sufficient binding region:69-6669(IPR000900)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929	uniprotkb:O60662	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660130|imex:IM-16425-465	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	intact-crc:B0E465770319F21B|rigid:45Vw+WOmLKllAfBkvWncSjQzy2k	false	sufficient binding region:3647-6669(IPR000900)	sufficient binding region:1-606	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60662	uniprotkb:P20929-4	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-9531519|ensembl:ENSP00000386259	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:p20929-4(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660112|imex:IM-16425-464	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	ensembl:ENSG00000183091(gene)|ensembl:ENST00000409198(transcript)|intact:EBI-1049657(isoform-parent)|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:aoHCLWV+j7ubdhBsylj1KjSUzwA9606	intact-crc:AFD4FBA91E0C5EFE|rigid:t/1XHrzfny+Z0U1sIA0+ZHfL5Ik	false	sufficient binding region:1-606	sufficient binding region:2616-6669(IPR000900)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929	uniprotkb:O60662	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660148|imex:IM-16425-466	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	intact-crc:0070D21EA6D52880|rigid:45Vw+WOmLKllAfBkvWncSjQzy2k	false	sufficient binding region:3841-6669(IPR000900)	sufficient binding region:1-606	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60662	uniprotkb:P20929	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660166|imex:IM-16425-467	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:D04889A409BEEB18|rigid:45Vw+WOmLKllAfBkvWncSjQzy2k	false	sufficient binding region:1-606	sufficient binding region:5328-6669(IPR000900)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929-4	uniprotkb:O60662	intact:EBI-9531519|ensembl:ENSP00000386259	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	psi-mi:p20929-4(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660184|imex:IM-16425-468	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183091(gene)|ensembl:ENST00000409198(transcript)|intact:EBI-1049657(isoform-parent)|genbank_protein_gi:115527119(identity)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aoHCLWV+j7ubdhBsylj1KjSUzwA9606	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	intact-crc:24441212641AA086|rigid:t/1XHrzfny+Z0U1sIA0+ZHfL5Ik	false	sufficient binding region:1763-6669(IPR000900)	sufficient binding region:1-606	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60662	uniprotkb:P20929	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660220|imex:IM-16425-470	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:31E1844741272A90|rigid:45Vw+WOmLKllAfBkvWncSjQzy2k	false	sufficient binding region:1-606	sufficient binding region:3099-6669(IPR000900)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60662	uniprotkb:P20929-4	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-9531519|ensembl:ENSP00000386259	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:p20929-4(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660202|imex:IM-16425-469	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	ensembl:ENSG00000183091(gene)|ensembl:ENST00000409198(transcript)|intact:EBI-1049657(isoform-parent)|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:aoHCLWV+j7ubdhBsylj1KjSUzwA9606	intact-crc:AE7DE83CF179D393|rigid:t/1XHrzfny+Z0U1sIA0+ZHfL5Ik	false	sufficient binding region:1-606	sufficient binding region:2738-6669(IPR000900)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929	uniprotkb:O60662	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660238|imex:IM-16425-471	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	intact-crc:82CCF6C8BF6F724C|rigid:45Vw+WOmLKllAfBkvWncSjQzy2k	false	sufficient binding region:3411-6669(IPR000900)	sufficient binding region:1-606	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60662	uniprotkb:P20929-4	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-9531519|ensembl:ENSP00000386259	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:p20929-4(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660256|imex:IM-16425-472	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	ensembl:ENSG00000183091(gene)|ensembl:ENST00000409198(transcript)|intact:EBI-1049657(isoform-parent)|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:aoHCLWV+j7ubdhBsylj1KjSUzwA9606	intact-crc:E75FF9C008A0C961|rigid:t/1XHrzfny+Z0U1sIA0+ZHfL5Ik	false	sufficient binding region:1-606	sufficient binding region:1177-6669(IPR000900)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60662	uniprotkb:P20929	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660274|imex:IM-16425-473	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:91BFDB5DFB5AA0B7|rigid:45Vw+WOmLKllAfBkvWncSjQzy2k	false	sufficient binding region:1-606	sufficient binding region:3767-6669(IPR000900)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86VF7	uniprotkb:O60662	intact:EBI-5660292|uniprotkb:Q86TC5|uniprotkb:Q86VF6|uniprotkb:Q719H6|uniprotkb:Q6PDB0|uniprotkb:Q8N8F9|uniprotkb:Q8N3R6|uniprotkb:Q96MG4|uniprotkb:Q6N059|uniprotkb:Q86TD6|uniprotkb:Q8TCH0|uniprotkb:Q5VWI4|uniprotkb:Q86TE6|uniprotkb:Q6N026|uniprotkb:Q5VWI3|uniprotkb:O15500|uniprotkb:Q6NSH8|uniprotkb:Q6MZK3|ensembl:ENSP00000353078	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	psi-mi:nrap_human(display_long)|uniprotkb:NRAP(gene name)|psi-mi:NRAP(display_short)	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660314|imex:IM-16425-474	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006166.3|refseq:NP_932326.2|refseq:NP_001248392.1|ensembl:ENSG00000197893(gene)|ensembl:ENST00000359988(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0071691"(cardiac muscle thin filament assembly)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR013998(Nebulin)|genbank_protein_gi:46049104(identity)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:42741668(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:B8gGc3ZBL+ibTS7bsszXBX3MTH09606	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	intact-crc:CAD575100F2AAC5A|rigid:avaZN2rjPnDkBcMXcYTKygqdD/4	false	sufficient binding region:1458-1730	sufficient binding region:1-606	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60333	uniprotkb:P36871	intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|ensembl:ENSP00000366290|ensembl:ENSP00000502065|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4	intact:EBI-2861475|uniprotkb:Q5BKZ9|uniprotkb:Q96J40|uniprotkb:Q9NTY4|uniprotkb:Q6NW22|uniprotkb:Q86U74|uniprotkb:Q16105|uniprotkb:B2R5N9|uniprotkb:B4DPV0|uniprotkb:Q16106|ensembl:ENSP00000360125	psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym)	psi-mi:pgm1_human(display_long)|uniprotkb:PGM1(gene name)|psi-mi:PGM1(display_short)|uniprotkb:Glucose phosphomutase 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660331|imex:IM-16425-475	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000054523(gene)|ensembl:ENST00000377086(transcript)|ensembl:ENST00000676179(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N|genbank_protein_gi:41393558(identity)	refseq:NP_001166289.1|refseq:NP_001166290.1|refseq:NP_002624.2|dip:DIP-60903N|reactome:R-HSA-5609974|reactome:R-HSA-6798695|reactome:R-HSA-3322077|ensembl:ENSG00000079739(gene)|ensembl:ENST00000371084(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900|rcsb pdb:5EPC|rcsb pdb:5F9C|rcsb pdb:5HSH|rcsb pdb:5JN5|rcsb pdb:5TR2|rcsb pdb:5VBI|rcsb pdb:5VEC|rcsb pdb:5VG7|rcsb pdb:5VIN|rcsb pdb:6SNO|rcsb pdb:6SNP|rcsb pdb:6SNQ|rcsb pdb:6UIQ|rcsb pdb:6UO6|genbank_protein_gi:21361620(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606	rogid:K9cGu3lfysJ4hVP0S0jewZsZjSE9606	intact-crc:D8CE8D2A179C28EF|rigid:sFYFRKxPxC/eOL1bbJFTuHdvl9o	false	sufficient binding region:797-1041	sufficient binding region:8-562(IPR005845)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UP2	uniprotkb:P63279	intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660349|imex:IM-16425-476	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N|genbank_protein_gi:33620774(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|genbank_protein_gi:35493970(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:F04D42D6F55BCE40|rigid:shUbZAfUofY/HZ3ccYnJhuehD/U	false	sufficient binding region:233-1188	sufficient binding region:1-158	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48059	uniprotkb:Q9P2N4	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	intact:EBI-5660371|uniprotkb:Q9NR29|uniprotkb:A1L4L0|uniprotkb:B9ZVN0|uniprotkb:B7ZVX9|ensembl:ENSP00000418735	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:ats9_human(display_long)|uniprotkb:KIAA1312(gene name synonym)|uniprotkb:ADAMTS9(gene name)|psi-mi:ADAMTS9(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660366|imex:IM-16425-477	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	refseq:NP_001305710.1|refseq:NP_891550.1|ensembl:ENSG00000163638(gene)|ensembl:ENST00000498707(transcript)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090673"(endothelial cell-matrix adhesion)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR012314(Peptidase M12B, GON-ADAMTSs)|interpro:IPR013273(Peptidase M12B, ADAM-TS)|interpro:IPR024079|interpro:IPR036383|interpro:IPR041645|reactome:R-HSA-1474228|reactome:R-HSA-5083635|reactome:R-HSA-5173214|genbank_protein_gi:33624895(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	rogid:2HpvGsnrH/CzZBNtC+viFBMiL1c9606	intact-crc:657C2DC8B0030CCB|rigid:IzvYo33dRM40PLciDDmSvcvr3Jg	false	sufficient binding region:1-325	sufficient binding region:1456-1935(IPR000884)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48059	uniprotkb:Q9UBB4	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	intact:EBI-702390|uniprotkb:O14998|uniprotkb:O15009|uniprotkb:Q6I9X4|uniprotkb:A6NLC4|uniprotkb:B4DG05|ensembl:ENSP00000252934	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:atx10_human(display_long)|uniprotkb:Spinocerebellar ataxia type 10 protein(gene name synonym)|uniprotkb:Brain protein E46 homolog(gene name synonym)|uniprotkb:ATXN10(gene name)|psi-mi:ATXN10(display_short)|uniprotkb:SCA10(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660392|imex:IM-16425-478	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	refseq:NP_001161093.1|refseq:NP_037368.1|ensembl:ENSG00000130638(gene)|ensembl:ENST00000252934(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:Q9UBB4|genbank_protein_gi:51093837(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	rogid:kQ+1aM5ZEzIlpH2lKWFGVSrCDww9606	intact-crc:20518ACBB65A317B|rigid:C7VyRE3JGQLRw7zDL1p/5i+luuw	false	sufficient binding region:1-325	sufficient binding region:38-475	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50461	uniprotkb:P48059	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660409|imex:IM-16425-479	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13|genbank_protein_gi:48762935(identity)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	intact-crc:2AA2CB8612ED657C|rigid:G8tNK/AmUyKudTdJ9X+Oslaw5qk	false	sufficient binding region:1-194	sufficient binding region:1-325	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48059	uniprotkb:P29279	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	intact:EBI-2835375|uniprotkb:Q9UDL6|uniprotkb:Q96QX2|uniprotkb:Q96A79|uniprotkb:Q6LCY0|uniprotkb:E1P578|ensembl:ENSP00000356954	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:ccn2_human(display_long)|uniprotkb:CCN2(gene name)|psi-mi:CCN2(display_short)|uniprotkb:CTGF(gene name synonym)|uniprotkb:Cellular communication network factor 2(gene name synonym)|uniprotkb:Connective tissue growth factor(gene name synonym)|uniprotkb:HCS24(gene name synonym)|uniprotkb:Hypertrophic chondrocyte-specific protein 24(gene name synonym)|uniprotkb:IGFBP8(gene name synonym)|uniprotkb:Insulin-like growth factor-binding protein 8(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660426|imex:IM-16425-480	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	go:"GO:0001525"(angiogenesis)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008544"(epidermis development)|go:"GO:0009611"(response to wounding)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016477"(cell migration)|go:"GO:0001503"(ossification)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032355"(response to estradiol)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034059"(response to anoxia)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050867"(positive regulation of cell activation)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR006208(Cystine knot)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012395(IGFBP-related, CNN)|interpro:IPR017891|interpro:IPR036383|interpro:IPR043973|reactome:R-HSA-2032785|reactome:R-HSA-8951671|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|ensembl:ENSG00000118523(gene)|ensembl:ENST00000367976(transcript)|go:"GO:0001502"(cartilage condensation)|refseq:NP_001892.1|genbank_protein_gi:98986335(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	rogid:49UlrN4n3y1PYiOptu1l0KPco+89606	intact-crc:2C1FF9DBC654C2E2|rigid:hVWlBIURz6jJXv2a4st3zI2Bycg	false	sufficient binding region:1-325	sufficient binding region:162-349..349	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48059	uniprotkb:Q06787	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	intact:EBI-366305|ensembl:ENSP00000359506|uniprotkb:Q5PQZ6|uniprotkb:Q16578|uniprotkb:Q99054|uniprotkb:A6NNH4|uniprotkb:D3DWT0|uniprotkb:D3DWT1|uniprotkb:D3DWT2|uniprotkb:G8JL90	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:fmr1_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|uniprotkb:Fragile X mental retardation protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660443|imex:IM-16425-481	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	ensembl:ENSG00000102081(gene)|ensembl:ENST00000370475(transcript)|refseq:NP_001172004.1|refseq:NP_001172005.1|refseq:NP_001172010.1|refseq:NP_001172011.1|refseq:NP_002015.1|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990812"(growth cone filopodium)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:Q06787|rcsb pdb:2BKD|rcsb pdb:2FMR|rcsb pdb:2LA5|rcsb pdb:2QND|rcsb pdb:4OVA|rcsb pdb:4QVZ|rcsb pdb:4QW2|rcsb pdb:5DE5|rcsb pdb:5DE8|rcsb pdb:5DEA|rcsb pdb:5UWJ|rcsb pdb:5UWO|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|dip:DIP-29509N|genbank_protein_gi:50053960(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	rogid:+iN/J/MbxTcRwgDezYseEDwLep49606	intact-crc:3CEB93F522C87EFD|rigid:PnuyZHeOpmBBovhsf+pxSd9wTRA	false	sufficient binding region:1-325	sufficient binding region:31-632(IPR008395)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13418	uniprotkb:P48059	intact:EBI-747644|uniprotkb:P57043|uniprotkb:Q68DZ3|uniprotkb:B7Z1I0|uniprotkb:D3DQU0|uniprotkb:B7Z418|ensembl:ENSP00000299421|ensembl:ENSP00000379975|ensembl:ENSP00000403487	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	psi-mi:ilk_human(display_long)|uniprotkb:ILK-1(gene name synonym)|uniprotkb:ILK-2(gene name synonym)|uniprotkb:59 kDa serine/threonine-protein kinase(gene name synonym)|uniprotkb:p59ILK(gene name synonym)|uniprotkb:ILK(gene name)|psi-mi:ILK(display_short)|uniprotkb:ILK1(gene name synonym)|uniprotkb:ILK2(gene name synonym)|uniprotkb:Beta-integrin-linked kinase(gene name synonym)	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660461|imex:IM-16425-482	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265370.1|refseq:NP_001014794.1|refseq:NP_001014795.1|refseq:NP_004508.1|refseq:XP_005252961.1|refseq:NP_001265371.1|refseq:XP_005252962.1|refseq:XP_011518367.1|dip:DIP-38657N|rcsb pdb:3IXE|rcsb pdb:3KMU|rcsb pdb:3KMW|rcsb pdb:3REP|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIB|reactome:R-HSA-446343|reactome:R-HSA-446353|ensembl:ENSG00000166333(gene)|ensembl:ENST00000299421(transcript)|ensembl:ENST00000396751(transcript)|ensembl:ENST00000420936(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021675"(nerve development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032288"(myelin assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070527"(platelet aggregation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR035692|interpro:IPR036770|mint:Q13418|rcsb pdb:2KBX|rcsb pdb:3F6Q|go:"GO:0045663"(positive regulation of myoblast differentiation)|genbank_protein_gi:62420874(identity)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:FrK/MsW7IcVWT9VbkHAIVHEh1P89606	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	intact-crc:30D6C04B8BDF5DDE|rigid:I/1DNAvCnNVdz42QXbhTVlKhHGw	false	sufficient binding region:29-452	sufficient binding region:1-325	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929-4	uniprotkb:P48059	intact:EBI-9531519|ensembl:ENSP00000386259	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	psi-mi:p20929-4(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660495|imex:IM-16425-484	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183091(gene)|ensembl:ENST00000409198(transcript)|intact:EBI-1049657(isoform-parent)|genbank_protein_gi:115527119(identity)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:aoHCLWV+j7ubdhBsylj1KjSUzwA9606	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	intact-crc:7B1A83BF04046405|rigid:CB04vg74PHm3hCO4Jmch37DZRPY	false	sufficient binding region:1033-6669	sufficient binding region:1-325	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48059	uniprotkb:O95373	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|intact:EBI-28976968|ensembl:ENSP00000369042	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660478|imex:IM-16425-483	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	ensembl:ENSP00000369042|refseq:NP_006382.1|dip:DIP-32574N|ensembl:ENSG00000205339(gene)|ensembl:ENST00000379719(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373|genbank_protein_gi:5453997(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606	intact-crc:4E9A7FFF36C4186D|rigid:p/9wI0QFoIGjDFmeMI/qxvjNq4o	false	sufficient binding region:1-325	sufficient binding region:602-1038	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N2R0	uniprotkb:P48059	intact:EBI-5660512|uniprotkb:Q96LB6|uniprotkb:A8K626|uniprotkb:Q96LB7|uniprotkb:Q96AM6|uniprotkb:B4E3B7|ensembl:ENSP00000297565|ensembl:ENSP00000430780	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	psi-mi:osr2_human(display_long)|uniprotkb:OSR2(gene name)|psi-mi:OSR2(display_short)	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660520|imex:IM-16425-485	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011515129.1|refseq:NP_001135934.1|refseq:NP_443727.2|refseq:NP_001273770.1|refseq:XP_016868507.1|ensembl:ENSG00000164920(gene)|ensembl:ENST00000297565(transcript)|ensembl:ENST00000522510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001823"(mesonephros development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060322"(head development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0072498"(embryonic skeletal joint development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|genbank_protein_gi:15418951(identity)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ehHTFgG6gR3dafyzeabBY1cbV389606	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	intact-crc:7110CCF1BCD28E39|rigid:HZjsL0uYjz9jF6yib5cL39/9ilU	false	sufficient binding region:97-312(IPR007087)	sufficient binding region:1-325	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9GZU2	uniprotkb:P48059	intact:EBI-1015078|uniprotkb:P78418|uniprotkb:Q5H9P9|uniprotkb:Q7Z7H7|uniprotkb:Q8TF75|uniprotkb:Q9GZY2|uniprotkb:A7E2B8|uniprotkb:B4DIM4|uniprotkb:C9JP50|intact:EBI-28979282|ensembl:ENSP00000326581|ensembl:ENSP00000469486|ensembl:ENSP00000472395	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	psi-mi:peg3_human(display_long)|uniprotkb:Zinc finger and SCAN domain-containing protein 24(gene name synonym)|uniprotkb:PEG3(gene name)|psi-mi:PEG3(display_short)|uniprotkb:KIAA0287(gene name synonym)|uniprotkb:ZSCAN24(gene name synonym)	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660538|imex:IM-16425-486	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139656.1|refseq:NP_001139657.1|refseq:NP_001139658.1|refseq:NP_001139659.1|refseq:NP_006201.1|ensembl:ENSP00000326581|ensembl:ENST00000593695|ensembl:ENSP00000472402|ensembl:ENST00000598410|ensembl:ENSP00000473190|ensembl:ENSP00000472395|ensembl:ENSP00000469486|ensembl:ENST00000648694|ensembl:ENSP00000496914|ensembl:ENST00000649233|ensembl:ENSP00000498047|ensembl:ENST00000649428|ensembl:ENSP00000498138|ensembl:ENST00000649680|ensembl:ENSP00000497512|ensembl:ENST00000649876|ensembl:ENSP00000496867|ensembl:ENST00000650102|ensembl:ENSP00000497466|ensembl:ENST00000650632|ensembl:ENSP00000497971|ensembl:ENSG00000198300(gene)|ensembl:ENST00000326441(transcript)|ensembl:ENST00000599534(transcript)|ensembl:ENST00000599577(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005776"(autophagosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|rcsb pdb:4BHX|dip:DIP-38426N|genbank_protein_gi:33354284(identity)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:7I+sAhnr9IzSlDKfAoB4oqiMSvY9606	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	intact-crc:44DDE6558364B6CA|rigid:4xS4kljkjH+HNieQQzmR56hROkM	false	sufficient binding region:300-1588(IPR007087)	sufficient binding region:1-325	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P212	uniprotkb:P48059	intact:EBI-721956|uniprotkb:A6NGW0|uniprotkb:A8K1D7|uniprotkb:Q5VWL4|uniprotkb:Q1X6H8|uniprotkb:Q5VWL5|uniprotkb:Q9H9X8|uniprotkb:Q9HBX6|uniprotkb:Q9HC53|uniprotkb:Q9UHV3|uniprotkb:A6NLA1|uniprotkb:A7MBN7|uniprotkb:B9EIJ6|ensembl:ENSP00000360431	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	psi-mi:plce1_human(display_long)|uniprotkb:Phospholipase C-epsilon-1(gene name synonym)|uniprotkb:Phosphoinositide phospholipase C-epsilon-1(gene name synonym)|uniprotkb:Pancreas-enriched phospholipase C(gene name synonym)|uniprotkb:PLCE1(gene name)|psi-mi:PLCE1(display_short)|uniprotkb:KIAA1516(gene name synonym)|uniprotkb:PLCE(gene name synonym)|uniprotkb:PPLC(gene name synonym)	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660556|imex:IM-16425-487	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001275918.1|refseq:NP_001159451.1|refseq:NP_057425.3|ensembl:ENSG00000138193(gene)|ensembl:ENST00000371380(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032835"(glomerulus development)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048016"(inositol phosphate-mediated signaling)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000159(Ras-association)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR011992(EF-Hand type)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR017946|interpro:IPR023578|interpro:IPR028398|interpro:IPR029071|interpro:IPR035892|rcsb pdb:2BYE|rcsb pdb:2BYF|rcsb pdb:2C5L|reactome:R-HSA-1855204|genbank_protein_gi:117168249(identity)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:OCuqUcjsCZfCW8Aa/n+DVoA17ls9606	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	intact-crc:D698AAA01D9C6915|rigid:AaH+so20wXr2hpiW1I6nZpUj/kA	false	sufficient binding region:1805-2302	sufficient binding region:1-325	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15404	uniprotkb:P48059	intact:EBI-1057132|uniprotkb:Q6FI17|uniprotkb:D3DRU3|uniprotkb:A8KA46|ensembl:ENSP00000339521|ensembl:ENSP00000367154	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	psi-mi:rsu1_human(display_long)|uniprotkb:RSU1(gene name)|psi-mi:RSU1(display_short)|uniprotkb:RSP1(gene name synonym)	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660573|imex:IM-16425-488	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689937.2|refseq:NP_036557.1|ensembl:ENSG00000148484(gene)|ensembl:ENST00000345264(transcript)|ensembl:ENST00000377921(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT8|rcsb pdb:7LT9|reactome:R-HSA-446388|genbank_protein_gi:34577084(identity)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:QZduUWmFxzAxRHmcdDbCQlm6tBQ9606	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	intact-crc:F96334E7D5A61444|rigid:bgZT2R2RrzN7dVdby/o6cAQ28yc	false	sufficient binding region:44-277(IPR003591)	sufficient binding region:1-325	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48059	uniprotkb:O75962	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	intact:EBI-718519|uniprotkb:Q13458|uniprotkb:Q59EQ7|uniprotkb:Q6PJC9|uniprotkb:Q6ZN05|uniprotkb:Q8IWK8|uniprotkb:D3DTD1|ensembl:ENSP00000339299	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:trio_human(display_long)|uniprotkb:PTPRF-interacting protein(gene name synonym)|uniprotkb:TRIO(gene name)|psi-mi:TRIO(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660591|imex:IM-16425-489	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	refseq:NP_009049.2|refseq:XP_011512412.1|ensembl:ENSG00000038382(gene)|ensembl:ENST00000344204(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0042995"(cell projection)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036179|interpro:IPR036865|mint:O75962|rcsb pdb:1NTY|rcsb pdb:2NZ8|rcsb pdb:6D8Z|reactome:R-HSA-193648|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418885|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|interpro:IPR008271(Serine/threonine protein kinase, active site)|dip:DIP-37578N|genbank_protein_gi:45439358(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	rogid:d01ioB7N6ccwAkeeoGpAa9GHZN89606	intact-crc:E5340CBC61FA6C2C|rigid:/BPLwwjVZPwctr6PjKr+7wsozT8	false	sufficient binding region:1-325	sufficient binding region:2549-3097	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P48059	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660608|imex:IM-16425-490	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	intact-crc:49FA22025640E032|rigid:txBmLFbkSJQVj3dp0KAVtkHv7vo	false	sufficient binding region:28345-34350(IPR003599)	sufficient binding region:1-325	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48059	uniprotkb:P51784	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660627|imex:IM-16425-491	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	ensembl:ENSG00000102226(gene)|ensembl:ENST00000218348(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:NP_004642.2|refseq:XP_011542290.1|refseq:XP_005272731.1|dip:DIP-27567N|genbank_protein_gi:75992939(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606	intact-crc:45F32C1CE14F75D3|rigid:5rL1etb9UeWPN6VhGw8gytQ7ZPA	false	sufficient binding region:1-325	sufficient binding region:722-963(IPR001394)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51784	uniprotkb:P48059	intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym)	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660645|imex:IM-16425-492	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102226(gene)|ensembl:ENST00000218348(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:NP_004642.2|refseq:XP_011542290.1|refseq:XP_005272731.1|dip:DIP-27567N|genbank_protein_gi:75992939(identity)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	intact-crc:AFFC91D581B7A8A9|rigid:5rL1etb9UeWPN6VhGw8gytQ7ZPA	false	sufficient binding region:153-963(IPR001394)	sufficient binding region:1-325	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VZL5	uniprotkb:P48059	intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym)	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660663|imex:IM-16425-493	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|genbank_protein_gi:44890067(identity)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	intact-crc:8DF44AC64F5014E4|rigid:uz9kQMJRpEdQwd5/wXw7owwj370	false	sufficient binding region:581-1548	sufficient binding region:1-325	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48059	uniprotkb:Q9HCG1	intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907	intact:EBI-2857453|intact:EBI-3922135|uniprotkb:Q14589|uniprotkb:Q504Q8|uniprotkb:Q96JC5|uniprotkb:Q9BVY9|uniprotkb:Q9H7N6|ensembl:ENSP00000406201|ensembl:ENSP00000409597|ensembl:ENSP00000470961|ensembl:ENSP00000507845	psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym)	psi-mi:zn160_human(display_long)|uniprotkb:ZNF160(gene name)|psi-mi:ZNF160(display_short)|uniprotkb:KIAA1611(gene name synonym)|uniprotkb:Zinc finger protein HZF5(gene name synonym)|uniprotkb:Zinc finger protein Kr18(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660680|imex:IM-16425-494	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N|genbank_protein_gi:47078283(identity)	refseq:NP_001309055.1|refseq:NP_001096073.1|refseq:NP_150630.2|refseq:NP_942596.1|refseq:NP_001309057.1|refseq:NP_001309058.1|refseq:NP_001309059.1|refseq:NP_001309060.1|refseq:NP_001309061.1|refseq:NP_001309062.1|refseq:NP_001309063.1|refseq:NP_001309064.1|refseq:NP_001309065.1|refseq:XP_016882935.1|refseq:XP_016882937.1|refseq:NP_001309054.1|ensembl:ENSG00000170949(gene)|ensembl:ENST00000418871(transcript)|ensembl:ENST00000429604(transcript)|ensembl:ENST00000599056(transcript)|ensembl:ENST00000683776(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030097"(hemopoiesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|genbank_protein_gi:38788301(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606	rogid:Q2G1Ettvdkbgz8bHt2bmZzOPRjg9606	intact-crc:7110B5216B57541F|rigid:sYe+XS+jTxW8BJtm6wFpB1Ditxo	false	sufficient binding region:1-325	sufficient binding region:115-818(IPR007087)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P0Q8	uniprotkb:P35609	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660698|imex:IM-16425-495	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|genbank_protein_gi:112363079(identity)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	intact-crc:D5BD47D1D160BB50|rigid:N+tNxIrE9Acq4AV4HjVDrpEYY8M	false	sufficient binding region:1001-1734	sufficient binding region:608-894..894	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P0Q8	uniprotkb:P84157	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	intact:EBI-5660715|uniprotkb:Q0P5W3|ensembl:ENSP00000348050	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:mxra7_human(display_long)|uniprotkb:MXRA7(gene name)|psi-mi:MXRA7(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660720|imex:IM-16425-496	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|genbank_protein_gi:112363079(identity)	refseq:NP_001008528.1|refseq:NP_001008529.1|refseq:NP_940932.2|ensembl:ENSG00000182534(gene)|ensembl:ENST00000355797(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR026622|genbank_protein_gi:56549132(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	rogid:5D8yzaF60a+81r61M5IhmtNhiNM9606	intact-crc:AA976CD74A25E131|rigid:CdsbFbvgRjAOQtmRRNNtpkIdt4g	false	sufficient binding region:1001-1734	sufficient binding region:159-204	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P0Q8	uniprotkb:P09493	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	intact:EBI-351158|uniprotkb:P09494|uniprotkb:P10469|uniprotkb:Q86W64|uniprotkb:Q96IK2|uniprotkb:Q9Y427|uniprotkb:Q9UCY9|uniprotkb:Q6DV89|uniprotkb:Q6DV90|uniprotkb:Q9UCI1|uniprotkb:Q9UCI2|uniprotkb:B7Z5T7|uniprotkb:Q7Z6L8|intact:EBI-2558177|ensembl:ENSP00000385107|intact:EBI-11030042|uniprotkb:D9YZV2|uniprotkb:D9YZV3|uniprotkb:D9YZV8	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:tpm1_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660737|imex:IM-16425-497	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|genbank_protein_gi:112363079(identity)	refseq:NP_000357.3|refseq:NP_001018005.1|refseq:NP_001018006.1|refseq:NP_001018008.1|ensembl:ENSG00000140416(gene)|ensembl:ENST00000403994(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|mint:P09493|rcsb pdb:3MUD|rcsb pdb:5KHT|rcsb pdb:6UT2|rcsb pdb:6X5Z|reactome:R-HSA-390522|reactome:R-HSA-445355|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001288173.1|refseq:NP_001018007.1|refseq:NP_001018004.1|refseq:NP_001018020.1|refseq:XP_016878027.1|refseq:NP_001317273.1|refseq:NP_001317275.1|refseq:NP_001317280.1|genbank_protein_gi:63252897(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	rogid:rsKuZnKpbEqVOpYBz3PnoSBCSHs9606	intact-crc:7DB18A7CE3FE6ABF|rigid:L2e4Lj+wlCoCRkqsr41TPvGNRxo	false	sufficient binding region:1001-1734	sufficient binding region:226-284..284(IPR000533)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07951	uniprotkb:Q6P0Q8	intact:EBI-352633|uniprotkb:P06468|uniprotkb:Q13894|uniprotkb:Q53FM4|uniprotkb:A6NM85|uniprotkb:Q5TCU4|uniprotkb:Q5TCU7|uniprotkb:Q9UH67|ensembl:ENSP00000496494	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	psi-mi:tpm2_human(display_long)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short)|uniprotkb:TMSB(gene name synonym)|uniprotkb:Tropomyosin-2(gene name synonym)|uniprotkb:Beta-tropomyosin(gene name synonym)	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660755|imex:IM-16425-498	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003280.2|refseq:NP_998839.1|mint:P07951|reactome:R-HSA-390522|reactome:R-HSA-445355|ensembl:ENSG00000198467(gene)|ensembl:ENST00000645482(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR000533(Tropomyosin)|refseq:XP_016870580.1|genbank_protein_gi:47519592(identity)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|genbank_protein_gi:112363079(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:uMqEpVZJ9ezKmeA67qQLCWBd/zo9606	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	intact-crc:9C5595943FD685BB|rigid:vk7lwUi3EKAho7mba6qVkHEetMg	false	sufficient binding region:223-284..284(IPR000533)	sufficient binding region:1001-1734	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P0Q8	uniprotkb:P06753	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|ensembl:ENSP00000498577|intact:EBI-11063811|uniprotkb:Q5VU66|uniprotkb:Q5VU72|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660773|imex:IM-16425-499	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|genbank_protein_gi:112363079(identity)	refseq:NP_001265120.1|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_689476.2|refseq:NP_705935.1|ensembl:ENSG00000143549(gene)|ensembl:ENST00000651641(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|refseq:NP_001036818.1|refseq:NP_001265118.1|genbank_protein_gi:114155139(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606	intact-crc:C61108037EC8C918|rigid:vj6VX62pmJRPsrO1U915tWUk4kc	false	sufficient binding region:1001-1734	sufficient binding region:229-285..285(IPR000533)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q6P0Q8	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660791|imex:IM-16425-500	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|genbank_protein_gi:112363079(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	intact-crc:DC34915EC44B26BA|rigid:4cemqk1d/L2DWjot4qq4gdcShPM	false	sufficient binding region:6704-34350	sufficient binding region:1001-1734	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAU3	uniprotkb:Q6P0Q8	intact:EBI-740727|uniprotkb:B4DEU1|ensembl:ENSP00000311319	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	psi-mi:zn417_human(display_long)|uniprotkb:ZNF417(gene name)|psi-mi:ZNF417(display_short)	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660808|imex:IM-16425-501	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689688.2|reactome:R-HSA-212436|ensembl:ENSG00000173480(gene)|ensembl:ENST00000312026(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q8TAU3|genbank_protein_gi:112983682(identity)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|genbank_protein_gi:112363079(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:pFgC/W5WDWNhvGGcKtaUaAGarpU9606	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	intact-crc:2039F0EE92CD9948|rigid:oxst07mwI/dMEliFTpdJNlu3pIw	false	sufficient binding region:1-575(IPR007087)	sufficient binding region:1001-1734	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15773	uniprotkb:O75190	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660826|imex:IM-16425-502	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773|genbank_protein_gi:4885486(identity)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:08341FE2EA9A9292|rigid:E8NyzVIbIHY7w4rq8WCmzGdxzPs	false	sufficient binding region:84-248	sufficient binding region:102-326	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJY1	uniprotkb:Q15773	intact:EBI-739074|uniprotkb:Q6FIH3|uniprotkb:Q9UKS3|ensembl:ENSP00000281938|uniprotkb:B2R6A6	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317	psi-mi:hspb8_human(display_long)|uniprotkb:HSPB8(gene name)|psi-mi:HSPB8(display_short)|uniprotkb:CRYAC(gene name synonym)|uniprotkb:E2IG1(gene name synonym)|uniprotkb:HSP22(gene name synonym)|uniprotkb:PP1629(orf name)|uniprotkb:Alpha-crystallin C chain(gene name synonym)|uniprotkb:Small stress protein-like protein HSP22(gene name synonym)|uniprotkb:E2-induced gene 1 protein(gene name synonym)|uniprotkb:Protein kinase H11(gene name synonym)	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660843|imex:IM-16425-503	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000152137(gene)|ensembl:ENST00000281938(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0101031"(chaperone complex)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR042790|interpro:IPR043254|reactome:R-HSA-3371571|refseq:NP_055180.1|genbank_protein_gi:7644379(identity)	refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773|genbank_protein_gi:4885486(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:SXMGg+TeGqU6CI+A4ypCqCGNYks9606	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	intact-crc:16825E7EC276A321|rigid:pxq5OJxtAZ/5mYiBTVU5bl4/fjs	false	sufficient binding region:31-196..196	sufficient binding region:84-248	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13674	uniprotkb:Q15773	intact:EBI-1237386|uniprotkb:Q15082|uniprotkb:Q15083|uniprotkb:Q5VSQ5|uniprotkb:C9JL12|ensembl:ENSP00000307318|ensembl:ENSP00000378353	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317	psi-mi:p4ha1_human(display_long)|uniprotkb:P4HA1(gene name)|psi-mi:P4HA1(display_short)|uniprotkb:P4HA(gene name synonym)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1(gene name synonym)	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660860|imex:IM-16425-504	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000908.2|refseq:NP_001017962.1|refseq:NP_001136067.1|refseq:NP_001136068.1|dip:DIP-38180N|ensembl:ENSG00000122884(gene)|ensembl:ENST00000307116(transcript)|ensembl:ENST00000394890(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|interpro:IPR019734|mint:P13674|rcsb pdb:1TJC|rcsb pdb:2V5F|rcsb pdb:2YQ8|rcsb pdb:4BT8|rcsb pdb:4BT9|rcsb pdb:4BTA|rcsb pdb:4BTB|reactome:R-HSA-1650814|go:"GO:0043231"(intracellular membrane-bounded organelle)|genbank_protein_gi:114631196(identity)	refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773|genbank_protein_gi:4885486(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Yo9hgWVJ5iUGITVWKfvjhTNX1lk9606	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	intact-crc:92E33B248A9CCDE4|rigid:xKjkrdahNtWKl+NwGJA9B0AefwA	false	sufficient binding region:1-534	sufficient binding region:84-248	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35609	uniprotkb:Q14324	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660877|imex:IM-16425-505	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:BE99B20B47A8A9E4|rigid:7CdHwPL5YLcGGj7ispTHu//vUd8	false	sufficient binding region:1-894..894	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16853	uniprotkb:Q14324	intact:EBI-3921628|uniprotkb:B2RCI5|uniprotkb:Q45F94|ensembl:ENSP00000312326|uniprotkb:L0L8N9|uniprotkb:K7ESB3	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:aoc3_human(display_long)|uniprotkb:AOC3(gene name)|psi-mi:AOC3(display_short)|uniprotkb:VAP1(gene name synonym)|uniprotkb:Copper amine oxidase(gene name synonym)|uniprotkb:HPAO(gene name synonym)|uniprotkb:Semicarbazide-sensitive amine oxidase(gene name synonym)|uniprotkb:Vascular adhesion protein 1(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660894|imex:IM-16425-506	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264660.1|refseq:NP_001264661.1|refseq:NP_003725.1|ensembl:ENSG00000131471(gene)|ensembl:ENST00000308423(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0009308"(amine metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048038"(quinone binding)|go:"GO:0052593"("tryptamine:oxygen oxidoreductase (deaminating) activity")|go:"GO:0052594"("aminoacetone:oxygen oxidoreductase(deaminating) activity")|go:"GO:0052595"(aliphatic-amine oxidase activity)|go:"GO:0052596"("phenethylamine:oxygen oxidoreductase (deaminating) activity")|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|interpro:IPR000269(Copper amine oxidase)|interpro:IPR015798(Copper amine oxidase, C-terminal)|interpro:IPR015800(Copper amine oxidase, N2-terminal)|interpro:IPR015802(Copper amine oxidase, N3-terminal)|interpro:IPR016182(Copper amine oxidase, N-terminal region)|interpro:IPR036460|rcsb pdb:1PU4|rcsb pdb:1US1|rcsb pdb:2C10|rcsb pdb:2C11|rcsb pdb:2Y73|rcsb pdb:2Y74|rcsb pdb:3ALA|rcsb pdb:4BTW|rcsb pdb:4BTX|rcsb pdb:4BTY|reactome:R-HSA-211945|genbank_protein_gi:6806883(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:t7ZSUp32sGH23Gfa+V0Lult17Fw9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:47403829FAD00559|rigid:6t38TwExXEcSj6petKmE4wHMc90	false	sufficient binding region:132-763	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q8N3K9	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660911|imex:IM-16425-507	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9|genbank_protein_gi:62241002(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	intact-crc:07751F8DB80D50E7|rigid:3+iAaWyx7vVCxboeeQAMg9A17e4	false	sufficient binding region:636-1141	sufficient binding region:3666-4069(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q99715	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-2528424|uniprotkb:O43853|uniprotkb:Q15955|uniprotkb:Q5VYK1|uniprotkb:Q5VYK2|uniprotkb:Q71UR3|uniprotkb:Q99716|ensembl:ENSP00000325146	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:coca1_human(display_long)|uniprotkb:COL12A1(gene name)|psi-mi:COL12A1(display_short)|uniprotkb:COL12A1L(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660948|imex:IM-16425-509	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_004361.3|refseq:NP_542376.2|ensembl:ENSG00000111799(gene)|ensembl:ENST00000322507(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005595"(collagen type XII trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001791(Laminin G)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036465|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8948216|genbank_protein_gi:93141048(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:F8PJe9hehPjh3IhjfQKxFcfmvlc9606	intact-crc:B9D69BC9E9665BC7|rigid:oRoE7f6EseuPYdcn5zzQ81NHdPE	false	sufficient binding region:636-1141	sufficient binding region:516-3063(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99715	uniprotkb:Q14324	intact:EBI-2528424|uniprotkb:O43853|uniprotkb:Q15955|uniprotkb:Q5VYK1|uniprotkb:Q5VYK2|uniprotkb:Q71UR3|uniprotkb:Q99716|ensembl:ENSP00000325146	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:coca1_human(display_long)|uniprotkb:COL12A1(gene name)|psi-mi:COL12A1(display_short)|uniprotkb:COL12A1L(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660930|imex:IM-16425-508	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004361.3|refseq:NP_542376.2|ensembl:ENSG00000111799(gene)|ensembl:ENST00000322507(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005595"(collagen type XII trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001791(Laminin G)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036465|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8948216|genbank_protein_gi:93141048(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:F8PJe9hehPjh3IhjfQKxFcfmvlc9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:8EB218161B3F89AB|rigid:oRoE7f6EseuPYdcn5zzQ81NHdPE	false	sufficient binding region:790-3063(IPR003961)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03001	uniprotkb:Q14324	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660966|imex:IM-16425-510	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:FF0FA3CA2F3EACD5|rigid:FJXzgFSA4h4ryiIAUkDpEOgiKlo	false	sufficient binding region:4378-7570	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:O75369	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5660983|imex:IM-16425-511	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1|genbank_protein_gi:105990513(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606	intact-crc:7AE7E7EAB5758D26|rigid:wPwuF5e4jVKF2sR4gymrMBz2Ayc	false	sufficient binding region:636-1141	sufficient binding region:1730-2602	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14315	uniprotkb:Q14324	intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661000|imex:IM-16425-512	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N|genbank_protein_gi:8885789(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:38CD387A2040231C|rigid:ftkI0tzxIdcCZ4HPWLMfIH+KmlQ	false	sufficient binding region:1571-2725(IPR001298)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q14315	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661018|imex:IM-16425-513	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N|genbank_protein_gi:8885789(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606	intact-crc:952AA33F5E08AD00|rigid:ftkI0tzxIdcCZ4HPWLMfIH+KmlQ	false	sufficient binding region:636-1141	sufficient binding region:162-2725(IPR001298)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A1L4K1	uniprotkb:Q14324	intact:EBI-5661036|uniprotkb:B3KVG1|uniprotkb:B7ZM02|ensembl:ENSP00000335651	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:fsd2_human(display_long)|uniprotkb:SPRY domain-containing protein 1(gene name synonym)|uniprotkb:SPRYD1(gene name synonym)|uniprotkb:FSD2(gene name)|psi-mi:FSD2(display_short)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661041|imex:IM-16425-514	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007123.1|refseq:XP_005272482.1|refseq:NP_001268734.1|refseq:NP_001268735.1|ensembl:ENSG00000186628(gene)|ensembl:ENST00000334574(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|genbank_protein_gi:55741631(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:XD3MwGtfyGillIn2aNaHaiAwEls9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:46956BD3E492D0E4|rigid:JcmfLWiJXtPDghThRwMyfdgWKA8	false	sufficient binding region:318-749(IPR003961)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95166	uniprotkb:Q14324	intact:EBI-712001|ensembl:ENSP00000306866	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:gbrap_human(display_long)|uniprotkb:"GABA(A) receptor-associated protein"(gene name synonym)|uniprotkb:MM46(gene name synonym)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:FLC3B(gene name synonym)|uniprotkb:HT004(orf name)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661060|imex:IM-16425-515	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000170296(gene)|ensembl:ENST00000302386(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006605"(protein targeting)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008017"(microtubule binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:O95166|rcsb pdb:1GNU|rcsb pdb:1KLV|rcsb pdb:1KM7|rcsb pdb:1KOT|rcsb pdb:3D32|rcsb pdb:3DOW|rcsb pdb:3WIM|rcsb pdb:4XC2|rcsb pdb:5DPS|rcsb pdb:6HB9|rcsb pdb:6HOG|rcsb pdb:6HOH|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:6HYL|rcsb pdb:6HYN|rcsb pdb:6HYO|rcsb pdb:6YOP|rcsb pdb:7AA8|rcsb pdb:7BRQ|rcsb pdb:7BRT|rcsb pdb:7BRU|rcsb pdb:7BV4|reactome:R-HSA-1632852|reactome:R-HSA-8854214|rcsb pdb:6HYM|refseq:NP_009209.1|dip:DIP-35050N|genbank_protein_gi:6005763(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PRC57VUrKgXozj1jnvgz7MQERK09606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:B692CE3C65CBAC9A|rigid:4nVdvUCubHUy3HZP2cCZX/foPI0	false	sufficient binding region:30-117..117	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60861	uniprotkb:Q14324	intact:EBI-2683717|uniprotkb:Q53Y77|uniprotkb:B2RCK9|uniprotkb:Q7Z571|uniprotkb:O43144|uniprotkb:A8KAC2|ensembl:ENSP00000407552	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:gas7_human(display_long)|uniprotkb:KIAA0394(gene name synonym)|uniprotkb:GAS7(gene name)|psi-mi:GAS7(display_short)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661077|imex:IM-16425-516	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011522346.1|refseq:NP_003635.2|refseq:NP_958836.1|refseq:NP_958839.1|refseq:NP_001124303.1|refseq:XP_005256888.1|refseq:XP_005256889.1|ensembl:ENSG00000007237(gene)|ensembl:ENST00000432992(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036020|interpro:IPR036028|interpro:IPR037957|rcsb pdb:2LX7|rcsb pdb:2YSH|refseq:XP_016880728.1|genbank_protein_gi:41406075(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:AGTjGZ7Nb4FN05kKzZ7POn5n+xQ9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:E54DB84DB31F3023|rigid:P0jbq+kXtNixUTJdHoBdjSB5dOE	false	sufficient binding region:102-476(IPR001060)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI95	uniprotkb:Q14324	intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661095|imex:IM-16425-517	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1|genbank_protein_gi:6006019(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:A587FF0E042761AB|rigid:tNlOi2QX8f75jfi9QRKLiJY/E/Q	false	sufficient binding region:13-211(IPR003511)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:P26038	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-528768|ensembl:ENSP00000353408	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:moes_human(display_long)|uniprotkb:Membrane-organizing extension spike protein(gene name synonym)|uniprotkb:MSN(gene name)|psi-mi:MSN(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661113|imex:IM-16425-518	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_002435.1|ensembl:ENSG00000147065(gene)|ensembl:ENST00000360270(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001931"(uropod)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005925"(focal adhesion)|go:"GO:0031982"(vesicle)|go:"GO:0042098"(T cell proliferation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070489"(T cell aggregation)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009986"(cell surface)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0072678"(T cell migration)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000401"(regulation of lymphocyte migration)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P26038|rcsb pdb:1E5W|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016323"(basolateral plasma membrane)|rcsb pdb:1EF1|rcsb pdb:1SGH|rcsb pdb:6TXQ|go:"GO:0016324"(apical plasma membrane)|rcsb pdb:6TXS|reactome:R-HSA-437239|reactome:R-HSA-8950505|reactome:R-HSA-9662360|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-9662361|go:"GO:0019901"(protein kinase binding)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0031143"(pseudopodium)|go:"GO:0031528"(microvillus membrane)|dip:DIP-33841N|genbank_protein_gi:53729335(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:XYzuC8VtaVyNYyZ2G5wVbxyPPww9606	intact-crc:A9660BA6A77CE8EB|rigid:CVuSgVPWmi5pRXmIRjbx9P798H0	false	sufficient binding region:636-1141	sufficient binding region:4-577	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q00872	uniprotkb:Q14324	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661130|imex:IM-16425-519	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:06A063255450C787|rigid:adfEF5Hjur0hi34JS+aMtpxn3/M	false	sufficient binding region:854-1141(IPR003599)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q00872	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661149|imex:IM-16425-520	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:9A2991B7BED5A573|rigid:adfEF5Hjur0hi34JS+aMtpxn3/M	false	sufficient binding region:636-1141	sufficient binding region:581-1141(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q00872	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661167|imex:IM-16425-521	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:12D9C7A6922DD3CB|rigid:adfEF5Hjur0hi34JS+aMtpxn3/M	false	sufficient binding region:636-1141	sufficient binding region:947-1141(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:P13535	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-1053673|uniprotkb:Q14910|ensembl:ENSP00000384330	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:myh8_human(display_long)|uniprotkb:Myosin heavy chain 8(gene name synonym)|uniprotkb:Myosin heavy chain, skeletal muscle, perinatal(gene name synonym)|uniprotkb:MYH8(gene name)|psi-mi:MYH8(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661185|imex:IM-16425-522	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	ensembl:ENSG00000133020(gene)|ensembl:ENST00000403437(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032982"(myosin filament)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-390522|refseq:NP_002463.2|genbank_protein_gi:4505300(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:TIj9VV/I3u0ATmh1NWi7SYbmpCY9606	intact-crc:F8285FBAD5F2551A|rigid:thdDA3K1TzQB8YfuGmEflQ715VM	false	sufficient binding region:636-1141	sufficient binding region:1227-1937	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:P54296	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661202|imex:IM-16425-523	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:31418211(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	intact-crc:7E1D25AEAB370DB4|rigid:JMpiO1ghUG2tRnYquLqXHvyE0gM	false	sufficient binding region:636-1141	sufficient binding region:852-1465(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54296	uniprotkb:Q14324	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661221|imex:IM-16425-524	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:31418211(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:D9699894E880B515|rigid:JMpiO1ghUG2tRnYquLqXHvyE0gM	false	sufficient binding region:409-1465(IPR003961)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35240	uniprotkb:Q14324	intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661239|imex:IM-16425-525	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N|genbank_protein_gi:32967259(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:915788FCF0DD83EE|rigid:tNh7edsIiy2E4m9mmEFehr4g14o	false	sufficient binding region:1-595	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q9NPG4	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-5661261|uniprotkb:Q9H8E0|uniprotkb:Q9H7Y6|uniprotkb:Q96KB8|uniprotkb:Q6UXB6|intact:EBI-28970249|ensembl:ENSP00000231484	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:pcd12_human(display_long)|uniprotkb:Vascular cadherin-2(gene name synonym)|uniprotkb:Vascular endothelial cadherin-2(gene name synonym)|uniprotkb:UNQ395/PRO731(orf name)|uniprotkb:PCDH12(gene name)|psi-mi:PCDH12(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661256|imex:IM-16425-526	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	ensembl:ENSP00000231484|refseq:NP_057664.1|dip:DIP-47292N|ensembl:ENSG00000113555(gene)|ensembl:ENST00000231484(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0008038"(neuron recognition)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR030720|mint:Q9NPG4|genbank_protein_gi:14589925(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:fGLd6OY1KErfbmXJ5BQYa2dlZao9606	intact-crc:80E4243CC25C1DCF|rigid:iWF7Jg9d5vOnqaZhIBRxkgqvB2M	false	sufficient binding region:636-1141	sufficient binding region:158-1184	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VU43	uniprotkb:Q14324	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661282|imex:IM-16425-527	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|genbank_protein_gi:50658072(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:5F9EF4CC436D3D4A|rigid:bvTVBr0/+r2pGX4PSaOyiANxF4k	false	sufficient binding region:1884-2346	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49792	uniprotkb:Q14324	intact:EBI-973138|intact:EBI-28970106|ensembl:ENSP00000283195|uniprotkb:Q13074|uniprotkb:Q15280|uniprotkb:Q53TE2|uniprotkb:Q59FH7	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:rbp2_human(display_long)|uniprotkb:RANBP2(gene name)|psi-mi:RANBP2(display_short)|uniprotkb:NUP358(gene name synonym)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup358(gene name synonym)|uniprotkb:Nucleoporin Nup358(gene name synonym)|uniprotkb:358 kDa nucleoporin(gene name synonym)|uniprotkb:p270(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661299|imex:IM-16425-528	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000153201(gene)|ensembl:ENST00000283195(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006457"(protein folding)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|reactome:R-HSA-168271|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|mint:P49792|reactome:R-HSA-168276|rcsb pdb:1RRP|reactome:R-HSA-168325|reactome:R-HSA-168333|rcsb pdb:1XKE|rcsb pdb:1Z5S|rcsb pdb:2LAS|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4GA0|rcsb pdb:4I9Y|rcsb pdb:4L6E|rcsb pdb:4LQW|rcsb pdb:5CLL|rcsb pdb:5CLQ|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-170822|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-180746|reactome:R-HSA-9648025|ensembl:ENSP00000283195|refseq:NP_006258.3|dip:DIP-37654N|genbank_protein_gi:19718756(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KB+rjfw8djVygvDpTncA0NO2MDY9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:564095351A7681AA|rigid:PFnwJEME4jCs2i4flCbVV3XIBYU	false	sufficient binding region:1030-3224	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969Q1	uniprotkb:Q14324	intact:EBI-5661333|uniprotkb:Q9BYV4|uniprotkb:Q96BD3|uniprotkb:Q96KD9|uniprotkb:Q5T2I1|uniprotkb:B4DN95|ensembl:ENSP00000363390	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:tri63_human(display_long)|uniprotkb:IRF(gene name synonym)|uniprotkb:Iris RING finger protein(gene name synonym)|uniprotkb:MURF1(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 28(gene name synonym)|uniprotkb:RNF28(gene name synonym)|uniprotkb:SMRZ(gene name synonym)|uniprotkb:Striated muscle RING zinc finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 63(gene name synonym)|uniprotkb:TRIM63(gene name)|psi-mi:TRIM63(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM63(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661341|imex:IM-16425-530	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115977.2|ensembl:ENSG00000158022(gene)|ensembl:ENST00000374272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR042667|mint:Q969Q1|rcsb pdb:2D8U|rcsb pdb:3DDT|rcsb pdb:4M3L|reactome:R-HSA-9615017|reactome:R-HSA-983168|genbank_protein_gi:19924162(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:fxaNyoTJdzJyjJb+QYEZ+d72DbA9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:1ED6D588EE389831|rigid:wrnxwewDsMcTRn472wjjKEnXPuY	false	sufficient binding region:129-353(IPR000315)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00560	uniprotkb:Q14324	intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661316|imex:IM-16425-529	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N|genbank_protein_gi:109731787(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:F6209A7FC59A07D2|rigid:Q1ubORcL3fRkvN8pYvr6o+sLbAE	false	sufficient binding region:63-298..298	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15643	uniprotkb:Q14324	intact:EBI-1047183|uniprotkb:O14689|uniprotkb:O15154|uniprotkb:O95949|uniprotkb:B2RUT2|uniprotkb:Q6MZL5|ensembl:ENSP00000267622	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:tripb_human(display_long)|uniprotkb:Golgi-associated microtubule-binding protein 210(gene name synonym)|uniprotkb:Clonal evolution-related gene on chromosome 14 protein(gene name synonym)|uniprotkb:Trip230(gene name synonym)|uniprotkb:TRIP11(gene name)|psi-mi:TRIP11(display_short)|uniprotkb:CEV14(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661359|imex:IM-16425-531	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004230.2|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006486"(protein glycosylation)|ensembl:ENSG00000100815(gene)|ensembl:ENST00000267622(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002079"(inner acrosomal membrane)|go:"GO:0002081"(outer acrosomal membrane)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003413"(chondrocyte differentiation involved in endochondral bone morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0030133"(transport vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0051216"(cartilage development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0099041"(vesicle tethering to Golgi)|interpro:IPR000237(GRIP)|mint:Q15643|reactome:R-HSA-5620924|reactome:R-HSA-6811438|reactome:R-HSA-9703465|ensembl:ENSP00000267622|dip:DIP-40357N|genbank_protein_gi:10863904(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:M/XOdT1ZPDaQqMuBXsAB5p6N9LY9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:0F1CB4AC5B5B1F08|rigid:SE9X7sLoWnoGxEwV8siTznWww8s	false	sufficient binding region:1101-1979	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q8WZ42	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661376|imex:IM-16425-532	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:352600835E0689A8|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:636-1141	sufficient binding region:13667-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q14324	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661394|imex:IM-16425-533	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:832B6FDB50273867|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:27204-34350(IPR003961)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q8WZ42	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661412|imex:IM-16425-534	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:9E14E59FFE587553|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:636-1141	sufficient binding region:8641-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q8WZ42	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661430|imex:IM-16425-535	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:CD5B10AAABB70B51|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:636-1141	sufficient binding region:6272-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q14324	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661448|imex:IM-16425-536	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:A2C04AEC6DBF2247|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:30805-34350(IPR003961)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q8WZ42	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661466|imex:IM-16425-537	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:84049025E2A0A3B7|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:636-1141	sufficient binding region:28264-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q14324	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661485|imex:IM-16425-538	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:A52601AD62680B34|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:13910-34350(IPR003961)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q14324	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661503|imex:IM-16425-539	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:5319FEF484FFFDCC|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:17423-34350(IPR003599)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q8WZ42	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661522|imex:IM-16425-540	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:FE7602BD491F637B|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:636-1141	sufficient binding region:14588-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q14324	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661540|imex:IM-16425-541	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:10060169D5E20E95|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:15302-34350(IPR003961)	sufficient binding region:636-1141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q8WZ42	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661558|imex:IM-16425-542	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:C55355B5E9877BC9|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:636-1141	sufficient binding region:15726-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q8WZ42	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661576|imex:IM-16425-543	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:D58B6F1F20AF97AB|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:636-1141	sufficient binding region:29236-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q8WZ42	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661595|imex:IM-16425-544	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:183CAA287CEA600A|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:636-1141	sufficient binding region:16327-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13203	uniprotkb:Q8WZ42	intact:EBI-5655165|uniprotkb:Q86YC5|uniprotkb:Q16886|ensembl:ENSP00000255416	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mybph_human(display_long)|uniprotkb:H-protein(gene name synonym)|uniprotkb:MYBPH(gene name)|psi-mi:MYBPH(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661614|imex:IM-16425-545	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004988.2|ensembl:ENSG00000133055(gene)|ensembl:ENST00000255416(transcript)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|genbank_protein_gi:28277416(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:G72i8b794rZ+W4VeZ7oCNuowG2I9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:448853AB9BE84342|rigid:/7du+IAhxgl7P94Q4FVkegvjk4w	false	sufficient binding region:1-477	sufficient binding region:27176-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q13203	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5655165|uniprotkb:Q86YC5|uniprotkb:Q16886|ensembl:ENSP00000255416	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:mybph_human(display_long)|uniprotkb:H-protein(gene name synonym)|uniprotkb:MYBPH(gene name)|psi-mi:MYBPH(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661633|imex:IM-16425-546	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_004988.2|ensembl:ENSG00000133055(gene)|ensembl:ENST00000255416(transcript)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|genbank_protein_gi:28277416(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:G72i8b794rZ+W4VeZ7oCNuowG2I9606	intact-crc:C7D06B5D4E97C526|rigid:/7du+IAhxgl7P94Q4FVkegvjk4w	false	sufficient binding region:13898-34350(IPR003961)	sufficient binding region:1-477	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13203	uniprotkb:Q8WZ42	intact:EBI-5655165|uniprotkb:Q86YC5|uniprotkb:Q16886|ensembl:ENSP00000255416	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mybph_human(display_long)|uniprotkb:H-protein(gene name synonym)|uniprotkb:MYBPH(gene name)|psi-mi:MYBPH(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661651|imex:IM-16425-547	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004988.2|ensembl:ENSG00000133055(gene)|ensembl:ENST00000255416(transcript)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|genbank_protein_gi:28277416(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:G72i8b794rZ+W4VeZ7oCNuowG2I9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:106068EB7EB5A088|rigid:/7du+IAhxgl7P94Q4FVkegvjk4w	false	sufficient binding region:1-477	sufficient binding region:16633-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96S82	uniprotkb:Q13203	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	intact:EBI-5655165|uniprotkb:Q86YC5|uniprotkb:Q16886|ensembl:ENSP00000255416	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:mybph_human(display_long)|uniprotkb:H-protein(gene name synonym)|uniprotkb:MYBPH(gene name)|psi-mi:MYBPH(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661669|imex:IM-16425-548	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1|genbank_protein_gi:41152105(identity)	refseq:NP_004988.2|ensembl:ENSG00000133055(gene)|ensembl:ENST00000255416(transcript)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|genbank_protein_gi:28277416(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	rogid:G72i8b794rZ+W4VeZ7oCNuowG2I9606	intact-crc:FFF5E035D8FC9DD0|rigid:3df0Al9DlPLv6mDKrAJkI+rNJcw	false	sufficient binding region:105-380	sufficient binding region:1-477	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NAP3	uniprotkb:Q13203	intact:EBI-5235984|uniprotkb:D3DNF6|intact:EBI-28968990|ensembl:ENSP00000372635|ensembl:ENSP00000406955|ensembl:ENSP00000426387|ensembl:ENSP00000490041	intact:EBI-5655165|uniprotkb:Q86YC5|uniprotkb:Q16886|ensembl:ENSP00000255416	psi-mi:zbt38_human(display_long)|uniprotkb:ZBTB38(gene name)|psi-mi:ZBTB38(display_short)	psi-mi:mybph_human(display_long)|uniprotkb:H-protein(gene name synonym)|uniprotkb:MYBPH(gene name)|psi-mi:MYBPH(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661686|imex:IM-16425-549	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000372635|ensembl:ENSP00000406955|ensembl:ENSP00000426387|ensembl:ENSP00000490041|refseq:XP_011510913.1|refseq:XP_005247314.1|refseq:XP_005247315.1|refseq:NP_001073881.2|refseq:XP_005247318.1|refseq:XP_016861541.1|refseq:XP_016861542.1|refseq:XP_016861543.1|refseq:XP_016861544.1|refseq:XP_016861545.1|refseq:XP_016861546.1|refseq:XP_016861547.1|refseq:XP_016861548.1|refseq:XP_016861549.1|refseq:XP_016861550.1|ensembl:ENSG00000177311(gene)|ensembl:ENST00000321464(transcript)|ensembl:ENST00000441582(transcript)|ensembl:ENST00000514251(transcript)|ensembl:ENST00000637056(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8NAP3|rcsb pdb:6E93|rcsb pdb:6E94|genbank_protein_gi:122937220(identity)	refseq:NP_004988.2|ensembl:ENSG00000133055(gene)|ensembl:ENST00000255416(transcript)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|genbank_protein_gi:28277416(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2hYBmm9S5uBZPL4JBUvGWQaTPak9606	rogid:G72i8b794rZ+W4VeZ7oCNuowG2I9606	intact-crc:458BA1061F40489E|rigid:3psJLLlfvi4P7jJndLYpOTLoXas	false	sufficient binding region:2-1195(IPR000210)	sufficient binding region:1-477	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52179	uniprotkb:Q8NF91	intact:EBI-5353249|uniprotkb:Q14BD6|uniprotkb:Q6H969|uniprotkb:Q6ZUU0|ensembl:ENSP00000348821	intact:EBI-928867|uniprotkb:E7EQI5|uniprotkb:O94890|uniprotkb:Q5JV19|uniprotkb:Q5JV22|uniprotkb:Q8N9P7|uniprotkb:Q8TCP1|uniprotkb:Q8WWW6|uniprotkb:Q8WWW7|uniprotkb:Q8WXF6|uniprotkb:Q96N17|uniprotkb:Q9C0A7|uniprotkb:Q9H525|uniprotkb:Q9H526|uniprotkb:Q9NS36|uniprotkb:Q9NU50|uniprotkb:Q9UJ06|uniprotkb:Q9UJ07|uniprotkb:Q9ULF8|uniprotkb:B3W695|uniprotkb:H0Y4C0|uniprotkb:Q3ZCV0|ensembl:ENSP00000356224	psi-mi:myom1_human(display_long)|uniprotkb:MYOM1(gene name)|psi-mi:MYOM1(display_short)|uniprotkb:190 kDa connectin-associated protein(gene name synonym)|uniprotkb:190 kDa titin-associated protein(gene name synonym)|uniprotkb:Myomesin family member 1(gene name synonym)	psi-mi:syne1_human(display_long)|uniprotkb:SYNE1(gene name)|psi-mi:SYNE1(display_short)|uniprotkb:KIAA0796(gene name synonym)|uniprotkb:KIAA1262(gene name synonym)|uniprotkb:KIAA1756(gene name synonym)|uniprotkb:MYNE1(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 1(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 1(gene name synonym)|uniprotkb:Myocyte nuclear envelope protein 1(gene name synonym)|uniprotkb:C6orf98(gene name synonym)|uniprotkb:Enaptin(gene name synonym)|uniprotkb:KASH domain-containing protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661704|imex:IM-16425-550	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59649N|refseq:NP_003794.3|refseq:NP_062830.1|ensembl:ENSG00000101605(gene)|ensembl:ENST00000356443(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P52179|rcsb pdb:2R15|rcsb pdb:2Y23|rcsb pdb:2Y25|rcsb pdb:3RBS|rcsb pdb:5FM4|rcsb pdb:5FM5|rcsb pdb:5FM8|rcsb pdb:6T3O|genbank_protein_gi:46249363(identity)	refseq:NP_001334631.1|refseq:NP_149062.1|refseq:NP_892006.3|ensembl:ENSG00000131018(gene)|ensembl:ENST00000367255(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006997"(nucleus organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030017"(sarcomere)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR036872|mint:Q8NF91|rcsb pdb:4DXR|rcsb pdb:6R15|rcsb pdb:6XF2|reactome:R-HSA-1221632|genbank_protein_gi:154277115(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5lfd5o+54eyer647zxvU0LX1wpM9606	rogid:6nWMBf60nycHwNcMMQJL5JqanEc9606	intact-crc:C50340D4B5C0EA23|rigid:As9QOtVWqe70PZOhY45idf8GswE	false	sufficient binding region:1-245	sufficient binding region:7276-8797	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35609	uniprotkb:P54296	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661721|imex:IM-16425-551	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:4505314(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	intact-crc:BEEBE8C526A6FF88|rigid:Od9gbwfo4GQrJsc8X0shHm1G/So	false	sufficient binding region:338-894	sufficient binding region:1-122	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15652	uniprotkb:P54296	intact:EBI-1224969|uniprotkb:Q5SQZ8|uniprotkb:Q5SQZ9|uniprotkb:Q5SR00|uniprotkb:Q7Z3E7|uniprotkb:Q8N3U0|uniprotkb:Q96KB9|uniprotkb:Q9P2G7|uniprotkb:A0T124|intact:EBI-28967816|ensembl:ENSP00000382204	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	psi-mi:jhd2c_human(display_long)|uniprotkb:JMJD1C(gene name)|psi-mi:JMJD1C(display_short)|uniprotkb:JHDM2C(gene name synonym)|uniprotkb:KIAA1380(gene name synonym)|uniprotkb:TRIP8(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1C(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 8(gene name synonym)	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661738|imex:IM-16425-552	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269877.1|refseq:NP_116165.1|ensembl:ENSP00000382204|ensembl:ENST00000542921|ensembl:ENSP00000444682|refseq:NP_001305082.1|refseq:NP_001305083.1|refseq:NP_001309181.1|refseq:NP_001309183.1|refseq:NP_001309187.1|refseq:XP_016871386.1|refseq:XP_016871387.1|dip:DIP-38114N|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007596"(blood coagulation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q15652|ensembl:ENSG00000171988(gene)|ensembl:ENST00000399262(transcript)|go:"GO:0000118"(histone deacetylase complex)|rcsb pdb:2YPD|rcsb pdb:5FZO|reactome:R-HSA-983231|genbank_protein_gi:118600980(identity)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:4505314(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:15Klx5csF2CGH8c1YZBcVfhxCac9606	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	intact-crc:D876DC4848C83627|rigid:GlHZVipF366fkyYwVE4h+rTCKf0	false	sufficient binding region:620-2540	sufficient binding region:1-122	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12883	uniprotkb:P54296	intact:EBI-519141|uniprotkb:Q14836|uniprotkb:Q14837|uniprotkb:Q14904|uniprotkb:Q16579|uniprotkb:Q2M1Y6|uniprotkb:Q92679|uniprotkb:Q9H1D5|ensembl:ENSP00000347507|uniprotkb:Q9UMM8|uniprotkb:A2TDB6|uniprotkb:B6D424|uniprotkb:Q9UDA2	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	psi-mi:myh7_human(display_long)|uniprotkb:Myosin heavy chain 7(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle beta isoform(gene name synonym)|uniprotkb:Myosin heavy chain slow isoform(gene name synonym)|uniprotkb:MYH7(gene name)|psi-mi:MYH7(display_short)|uniprotkb:MYHCB(gene name synonym)	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661755|imex:IM-16425-553	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092054(gene)|ensembl:ENST00000355349(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031449"(regulation of slow-twitch skeletal muscle fiber contraction)|go:"GO:0032982"(myosin filament)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P12883|rcsb pdb:1IK2|rcsb pdb:2FXM|rcsb pdb:2FXO|rcsb pdb:3DTP|rcsb pdb:4DB1|rcsb pdb:4P7H|rcsb pdb:4PA0|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA4|rcsb pdb:4XA6|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ1|rcsb pdb:5CJ4|rcsb pdb:5TBY|rcsb pdb:5WJ7|rcsb pdb:5WJB|rcsb pdb:5WLQ|rcsb pdb:5WLZ|rcsb pdb:5WME|rcsb pdb:6PF2|rcsb pdb:6PFP|refseq:NP_000248.2|refseq:XP_016876829.1|genbank_protein_gi:115496168(identity)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:4505314(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Fz6cO12gihAyDMe06hLrQbrupbs9606	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	intact-crc:D9B1D6B5183231A8|rigid:xAanbu17Uehb/z8AWPiBrJFdVaw	false	sufficient binding region:1432-1935	sufficient binding region:1-122	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54296	uniprotkb:P54296	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661772|imex:IM-16425-554	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:31418211(identity)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:31418211(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	intact-crc:A05607AF7738C7A0|rigid:UvWjt5VaIub89ITDPQEIooVW5o4	false	sufficient binding region:512-1465	sufficient binding region:234-1465(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54296	uniprotkb:P20929	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661790|imex:IM-16425-555	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:31418211(identity)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	intact-crc:D513EF9A9EC1040C|rigid:fZRcnjRCyA1oZ9Mp9kfV73vKxkQ	false	sufficient binding region:512-1465	sufficient binding region:5316-6669	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62753	uniprotkb:P54296	intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name)	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661807|imex:IM-16425-556	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N|genbank_protein_gi:17158043(identity)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:31418211(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:beDuXCIqL99V9JlVfpzx7MdpH689606	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	intact-crc:488C0E65DFFA5901|rigid:YGSOu8SLgiHDZsA2D4HWUhK5TP0	false	sufficient binding region:1-249	sufficient binding region:512-1465	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21817	uniprotkb:P54296	intact:EBI-1221290|uniprotkb:Q16314|uniprotkb:Q16368|uniprotkb:Q9NPK1|uniprotkb:Q9P1U4|ensembl:ENSP00000352608	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	psi-mi:ryr1_human(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:RYDR(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym)	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661824|imex:IM-16425-557	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000531.2|refseq:NP_001036188.1|dip:DIP-29708N|ensembl:ENSG00000196218(gene)|ensembl:ENST00000359596(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031674"(I band)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:6UHI|rcsb pdb:6UHS|reactome:R-HSA-2672351|reactome:R-HSA-5578775|genbank_protein_gi:113204616(identity)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:4505314(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:WHlPtd5++5f+9GX0IGshsqJCOTg9606	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	intact-crc:E4BA23FD312070AC|rigid:F/BZnuGxcVQrM0kHfICU26VwylA	false	sufficient binding region:2001-5038	sufficient binding region:1-122	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54296	uniprotkb:O94979	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-1767898|uniprotkb:Q17RR5|uniprotkb:Q5H9P6|uniprotkb:Q5XG74|uniprotkb:Q659G7|uniprotkb:Q6ZU90|uniprotkb:Q7LCX9|uniprotkb:Q86TJ0|uniprotkb:Q8IZH4|uniprotkb:Q9P048|uniprotkb:Q9P0A6|uniprotkb:Q9UM05|uniprotkb:Q9UM06|uniprotkb:B7ZKZ7|uniprotkb:B7ZL00|uniprotkb:B4DIW6|uniprotkb:H7C2W3|ensembl:ENSP00000347329|ensembl:ENSP00000378721|ensembl:ENSP00000400926	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:sc31a_human(display_long)|uniprotkb:SEC31A(gene name)|psi-mi:SEC31A(display_short)|uniprotkb:KIAA0905(gene name synonym)|uniprotkb:SEC31L1(gene name synonym)|uniprotkb:HSPC275(orf name)|uniprotkb:HSPC334(orf name)|uniprotkb:SEC31-related protein A(gene name synonym)|uniprotkb:SEC31-like protein 1(gene name synonym)|uniprotkb:ABP125(gene name synonym)|uniprotkb:ABP130(gene name synonym)|uniprotkb:Web1-like protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661841|imex:IM-16425-558	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:4505314(identity)	refseq:NP_001070674.1|refseq:NP_001070675.1|refseq:NP_001070676.1|refseq:NP_057295.2|refseq:NP_001305048.1|refseq:NP_001305049.1|refseq:NP_001287673.1|refseq:NP_001287674.1|refseq:NP_001177978.1|dip:DIP-40438N|ensembl:ENSG00000138674(gene)|ensembl:ENST00000355196(transcript)|ensembl:ENST00000395310(transcript)|ensembl:ENST00000448323(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030120"(vesicle coat)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024298|interpro:IPR036322|interpro:IPR040251|mint:O94979|rcsb pdb:3WXA|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-381038|reactome:R-HSA-983170|genbank_protein_gi:116256339(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:MvtQi/4RmQ0siNtNoYH6k1rPv1Y9606	intact-crc:64F2C2BBAFD6BEC1|rigid:EUWIsIXtMXdBQzB+Ah/l6JRS8Tg	false	sufficient binding region:1-122	sufficient binding region:565-1220	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54296	uniprotkb:P21675	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661858|imex:IM-16425-559	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:4505314(identity)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N|genbank_protein_gi:20357587(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	intact-crc:210D6EEE7042A970|rigid:wAWXrhPZ80c99BjwlqAf1c9x+HM	false	sufficient binding region:1-122	sufficient binding region:1047-1872	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54296	uniprotkb:P13805	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	intact:EBI-726527|uniprotkb:O95472|uniprotkb:Q16061|uniprotkb:Q5U0E1|ensembl:ENSP00000467176	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:tnnt1_human(display_long)|uniprotkb:Slow skeletal muscle troponin T(gene name synonym)|uniprotkb:TNNT1(gene name)|psi-mi:TNNT1(display_short)|uniprotkb:TNT(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661875|imex:IM-16425-560	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:4505314(identity)	refseq:NP_001278703.1|refseq:NP_001119604.1|refseq:NP_001119605.1|refseq:NP_003274.3|refseq:XP_016882675.1|ensembl:ENSG00000105048(gene)|ensembl:ENST00000588981(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005861"(troponin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0031014"(troponin T binding)|go:"GO:0031444"(slow-twitch skeletal muscle fiber contraction)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045932"(negative regulation of muscle contraction)|interpro:IPR001978(Troponin)|interpro:IPR027707|interpro:IPR038077|mint:P13805|reactome:R-HSA-390522|genbank_protein_gi:21706666(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	rogid:zYApSOt95yJcjJZHRMuHR9C5Kqw9606	intact-crc:FBFA57041C073612|rigid:HnlLpDJhvbqSpZ0RJhX3NaTP09E	false	sufficient binding region:1-122	sufficient binding region:83-278(IPR001978)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86SG2	uniprotkb:P55209	intact:EBI-5661893|uniprotkb:Q711K7|uniprotkb:Q8NAJ7|ensembl:ENSP00000321679|ensembl:ENSP00000398987	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	psi-mi:anr23_human(display_long)|uniprotkb:DARP(gene name synonym)|uniprotkb:Diabetes-related ankyrin repeat protein(gene name synonym)|uniprotkb:Muscle ankyrin repeat protein 3(gene name synonym)|uniprotkb:ANKRD23(gene name)|psi-mi:ANKRD23(display_short)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661899|imex:IM-16425-561	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659431.5|ensembl:ENSG00000163126(gene)|ensembl:ENST00000318357(transcript)|ensembl:ENST00000418232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028780|interpro:IPR036770|genbank_protein_gi:89264742(identity)	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|genbank_protein_gi:33876637(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:1jKHN5jeUhA/l/4RJICbEwRR0aQ9606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	intact-crc:5C1D47C174A7432F|rigid:3sG4HqhNlApmsdi4ZyqFUA0YkTM	false	sufficient binding region:1-305	sufficient binding region:1-391	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55209	uniprotkb:P55209	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661916|imex:IM-16425-562	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|genbank_protein_gi:33876637(identity)	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|genbank_protein_gi:33876637(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	intact-crc:8996802F5F34997A|rigid:SPpEHr0TxtwMBzV9DjmL9EzdhH0	false	sufficient binding region:57-391(IPR002164)	sufficient binding region:1-391	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55209	uniprotkb:P62750	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661934|imex:IM-16425-563	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|genbank_protein_gi:33876637(identity)	reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|genbank_protein_gi:78190460(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606	intact-crc:FB2682EAC536283D|rigid:ztFJZnZZ30KQWgtEO6q7JmWHYTY	false	sufficient binding region:1-391	sufficient binding region:30-156(IPR005633)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55209	uniprotkb:P62841	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	intact:EBI-372635|uniprotkb:Q3KRA1|uniprotkb:P11174|uniprotkb:A5D8V9|uniprotkb:Q9UDC2|ensembl:ENSP00000467466	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:rs15_human(display_long)|uniprotkb:RIG protein(gene name synonym)|uniprotkb:RPS15(gene name)|psi-mi:RPS15(display_short)|uniprotkb:RIG(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS19(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661952|imex:IM-16425-564	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|genbank_protein_gi:33876637(identity)	refseq:NP_001009.1|mint:P62841|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|ensembl:ENSG00000115268(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|ensembl:ENST00000592588(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0097421"(liver regeneration)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|interpro:IPR020934|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR023575|rcsb pdb:6ZVH|rcsb pdb:6ZMT|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6ZMW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|genbank_protein_gi:124249379(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rogid:lJJOew1txuTwFlhKu4Z+AkPS5H09606	intact-crc:D970FA8CD3574F81|rigid:IWohoEG5Kh4+RzcXLP2YK1DcKnQ	false	sufficient binding region:1-391	sufficient binding region:23-145(IPR005713)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q13023	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-1056102|uniprotkb:O15028|uniprotkb:A7E2D4|uniprotkb:A7E242|ensembl:ENSP00000280979	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:akap6_human(display_long)|uniprotkb:KIAA0311(gene name synonym)|uniprotkb:AKAP6(gene name)|psi-mi:AKAP6(display_short)|uniprotkb:AKAP100(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 6(gene name synonym)|uniprotkb:A-kinase anchor protein 100 kDa(gene name synonym)|uniprotkb:mAKAP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661970|imex:IM-16425-565	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_004265.3|ensembl:ENSG00000151320(gene)|ensembl:ENST00000280979(transcript)|go:"GO:0001508"(action potential)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005901"(caveola)|go:"GO:0006605"(protein targeting)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030315"(T-tubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902261"(positive regulation of delayed rectifier potassium channel activity)|interpro:IPR018159|mint:Q13023|genbank_protein_gi:21493044(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:N0OdGKZGo4mR8XfkEGELhmoAGlA9606	intact-crc:87001598E38B7C78|rigid:mcMkLncFvAsmvzdop0v26+5gBE8	false	-	sufficient binding region:1066-2319(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:A0AUZ9	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-5661988|uniprotkb:Q9UFC3|uniprotkb:Q53TW3|uniprotkb:Q96MI0|uniprotkb:Q6IS05|uniprotkb:B7ZLN1|uniprotkb:Q53TV8|uniprotkb:Q8TCI1|uniprotkb:I6L9A8|ensembl:ENSP00000281772	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:kal1l_human(display_long)|uniprotkb:KANSL1L(gene name)|psi-mi:KANSL1L(display_short)|uniprotkb:C2orf67(gene name synonym)|uniprotkb:MSL1v2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5661999|imex:IM-16425-566	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_001294905.1|refseq:XP_011509008.1|refseq:XP_011509009.1|refseq:NP_689732.2|refseq:XP_005246386.1|refseq:XP_005246387.1|refseq:XP_016858919.1|ensembl:ENSG00000144445(gene)|ensembl:ENST00000281772(transcript)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|interpro:IPR026180|interpro:IPR029332|genbank_protein_gi:40217793(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:Erd/YfUzGvgzVNRrt7XuoiCBgLQ9606	intact-crc:B538DC37C221AFCE|rigid:u/l5LLheTi4oG09ZSFQe3t4BpeU	false	-	sufficient binding region:181-987	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q00610	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662016|imex:IM-16425-567	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424|genbank_protein_gi:115527063(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606	intact-crc:13900E1B2D65CFF5|rigid:/60oB7QvQgc39YPXtcZs4RChkUo	false	-	sufficient binding region:1056-1675(IPR000547)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q8N3K9	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662034|imex:IM-16425-568	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9|genbank_protein_gi:62241002(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	intact-crc:BE88D9659219A97A|rigid:BmIDzeCjYZM2QJUpRGvxkdY3sSo	false	-	sufficient binding region:3490-4069	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q03001	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662051|imex:IM-16425-569	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	intact-crc:9E9B31E182A4EF82|rigid:CSQGqVx78mA9/BXHhqr6r8SWuvY	false	-	sufficient binding region:3540-7570	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86YF9	uniprotkb:Q96CV9	intact:EBI-998108|uniprotkb:Q8WY45|uniprotkb:Q8WY46|uniprotkb:Q9UGA5|uniprotkb:Q9Y2K0|uniprotkb:Q5W078|uniprotkb:Q5W079|intact:EBI-28972311|ensembl:ENSP00000257312|ensembl:ENSP00000366025	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:dzip1_human(display_long)|uniprotkb:DAZ-interacting protein 1/2(gene name synonym)|uniprotkb:DZIP1(gene name)|psi-mi:DZIP1(display_short)|uniprotkb:DZIP(gene name synonym)|uniprotkb:DZIP2(gene name synonym)|uniprotkb:KIAA0996(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662068|imex:IM-16425-570	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000257312|ensembl:ENST00000361156|ensembl:ENSP00000355018|ensembl:ENST00000361396|ensembl:ENSP00000355175|ensembl:ENSP00000366025|ensembl:ENST00000466569|ensembl:ENSP00000431168|ensembl:ENSG00000134874(gene)|ensembl:ENST00000347108(transcript)|ensembl:ENST00000376829(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032714|reactome:R-HSA-5632684|refseq:NP_055749.1|refseq:NP_945319.1|dip:DIP-35710N|genbank_protein_gi:112789558(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:Ai+aFcCrkSRsORpfO7EATMi0HHg9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:3DA61D5681A5A68D|rigid:pIu7WdTnJXKJUFby0eKpv6f9yAU	false	sufficient binding region:136-867(IPR007087)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:P02794	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-713259|uniprotkb:Q3KRA8|uniprotkb:Q3SWW1|ensembl:ENSP00000273550|ensembl:ENSP00000484477|uniprotkb:B3KNR5	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:frih_human(display_long)|uniprotkb:Cell proliferation-inducing gene 15 protein(gene name synonym)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short)|uniprotkb:FTH(gene name synonym)|uniprotkb:FTHL6(gene name synonym)|uniprotkb:PIG15(orf name)|uniprotkb:OK/SW-cl.84(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662086|imex:IM-16425-571	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_002023.2|ensembl:ENSG00000167996(gene)|ensembl:ENST00000273550(transcript)|ensembl:ENST00000620041(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006955"(immune response)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0044754"(autolysosome)|mint:P02794|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1FHA|rcsb pdb:2CEI|rcsb pdb:2CHI|rcsb pdb:2CIH|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|rcsb pdb:2CLU|rcsb pdb:2CN6|rcsb pdb:2CN7|rcsb pdb:2FHA|rcsb pdb:2IU2|rcsb pdb:2Z6M|rcsb pdb:3AJO|rcsb pdb:3AJP|rcsb pdb:3AJQ|rcsb pdb:3ERZ|rcsb pdb:3ES3|rcsb pdb:4DYX|rcsb pdb:4DYY|rcsb pdb:4DYZ|rcsb pdb:4Y08|rcsb pdb:4YKH|rcsb pdb:4ZJK|rcsb pdb:5CMQ|rcsb pdb:5CMR|rcsb pdb:5GN8|rcsb pdb:5GOU|rcsb pdb:5JKK|rcsb pdb:5JKL|rcsb pdb:5JKM|rcsb pdb:5N26|rcsb pdb:5N27|rcsb pdb:5UP7|rcsb pdb:5UP8|rcsb pdb:5UP9|rcsb pdb:5VTD|rcsb pdb:5XB1|rcsb pdb:5YI5|rcsb pdb:5ZND|rcsb pdb:6B8F|rcsb pdb:6B8G|rcsb pdb:4DZ0|rcsb pdb:6FTV|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6H6T|rcsb pdb:6H6U|rcsb pdb:6IPC|rcsb pdb:6IPO|rcsb pdb:6IPP|rcsb pdb:6IPQ|rcsb pdb:6J4A|rcsb pdb:6J7G|rcsb pdb:6JOB|rcsb pdb:6JPS|rcsb pdb:6KE2|rcsb pdb:6KE4|rcsb pdb:4OYN|rcsb pdb:6M52|rcsb pdb:6M54|rcsb pdb:6WYF|rcsb pdb:6WYG|rcsb pdb:6WYH|rcsb pdb:6Z6U|rcsb pdb:6Z9E|rcsb pdb:6Z9F|rcsb pdb:7A6A|rcsb pdb:7A6B|rcsb pdb:7CK8|rcsb pdb:7CK9|rcsb pdb:7JGK|rcsb pdb:7JGL|rcsb pdb:7JGM|rcsb pdb:7JGN|rcsb pdb:7JGO|rcsb pdb:7JGP|rcsb pdb:7JGQ|rcsb pdb:7K26|rcsb pdb:7K3V|rcsb pdb:7K3W|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-38301N|genbank_protein_gi:32442331(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:TchHgRpv+inA8BQ5i0OHaa267tQ9606	intact-crc:4587B3C5D79A03DB|rigid:f3TXg2r4CiJzlyHNyO6qM7G72J8	false	-	sufficient binding region:7-183	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11055	uniprotkb:Q96CV9	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662103|imex:IM-16425-572	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:5BEE3AFA231C2B09|rigid:Qfg2bvAJ+1H0mdyGdmx2uIvfKyk	false	sufficient binding region:1522-1940(IPR002928)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:P20929-4	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-9531519|ensembl:ENSP00000386259	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:p20929-4(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662121|imex:IM-16425-573	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	ensembl:ENSG00000183091(gene)|ensembl:ENST00000409198(transcript)|intact:EBI-1049657(isoform-parent)|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:aoHCLWV+j7ubdhBsylj1KjSUzwA9606	intact-crc:2663B8E41A44BD7F|rigid:F/7KpdPa+MCjZvbFCj/SvHqm0uI	false	-	sufficient binding region:1226-6669	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929-4	uniprotkb:Q96CV9	intact:EBI-9531519|ensembl:ENSP00000386259	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:p20929-4(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662138|imex:IM-16425-574	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183091(gene)|ensembl:ENST00000409198(transcript)|intact:EBI-1049657(isoform-parent)|genbank_protein_gi:115527119(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:aoHCLWV+j7ubdhBsylj1KjSUzwA9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:9ADCE6E1E1C26AE6|rigid:F/7KpdPa+MCjZvbFCj/SvHqm0uI	false	sufficient binding region:2473-6669	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q96CV9	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662155|imex:IM-16425-575	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:21619682(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:9E136C99A5F91276|rigid:VN4obsiEl5BWaypitpZC/PUubYE	false	-	sufficient binding region:346-577	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q96CV9	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662172|imex:IM-16425-576	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:21619682(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:0C8ABB49DBB0BB7B|rigid:VN4obsiEl5BWaypitpZC/PUubYE	false	sufficient binding region:334-577	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14BN4	uniprotkb:Q96CV9	intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662189|imex:IM-16425-577	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1|genbank_protein_gi:56550042(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:D1AFC075F7FBC6BF|rigid:5aSoOuW3zxbcsTNvce56FlFRCfQ	false	sufficient binding region:84-828(IPR000253)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q9UNH7	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662207|imex:IM-16425-578	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|genbank_protein_gi:88703040(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	intact-crc:48C5E20B4AE0CDD5|rigid:zjXWH/zYtC70GAiqaTnw4icK5HA	false	-	sufficient binding region:368-406..406	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q9UHD2	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-356402|intact:EBI-5773956|intact:EBI-1383470|uniprotkb:Q8IYV3|uniprotkb:Q9NUJ5|ensembl:ENSP00000329967|ensembl:ENSP00000498995|uniprotkb:A8K4S4	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:tbk1_human(display_long)|uniprotkb:TBK1(gene name)|psi-mi:TBK1(display_short)|uniprotkb:NAK(gene name synonym)|uniprotkb:TANK-binding kinase 1(gene name synonym)|uniprotkb:T2K(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662224|imex:IM-16425-579	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_037386.1|go:"GO:0004672"(protein kinase activity)|ensembl:ENSG00000183735(gene)|ensembl:ENST00000331710(transcript)|ensembl:ENST00000650790(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901214"(regulation of neuron death)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR041087|interpro:IPR041309|mint:Q9UHD2|rcsb pdb:4EFO|rcsb pdb:4EUT|rcsb pdb:4EUU|rcsb pdb:4IM0|rcsb pdb:4IM2|rcsb pdb:4IM3|rcsb pdb:4IW0|rcsb pdb:4IWO|rcsb pdb:4IWP|rcsb pdb:4IWQ|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:5EP6|rcsb pdb:5W5V|rcsb pdb:6BNY|rcsb pdb:6BOD|rcsb pdb:6BOE|rcsb pdb:6CQ0|rcsb pdb:6CQ4|rcsb pdb:6CQ5|rcsb pdb:6NT9|rcsb pdb:6O8B|rcsb pdb:6RSR|rcsb pdb:6RST|rcsb pdb:6RSU|reactome:R-HSA-1606341|reactome:R-HSA-168928|reactome:R-HSA-3134975|reactome:R-HSA-3249367|reactome:R-HSA-3270619|reactome:R-HSA-9008059|reactome:R-HSA-9013973|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-9679191|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|refseq:XP_005268866.1|refseq:XP_005268867.1|dip:DIP-27529N|genbank_protein_gi:19743810(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:Cf+RbPJBZTpm7XIqbAD2OEC6VEs9606	intact-crc:906DE9C78EB67FD8|rigid:wwuKbyeoXJf+yXxZjKlMVRJ0GSk	false	-	sufficient binding region:661-729..729	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q15025	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662241|imex:IM-16425-580	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|genbank_protein_gi:116256480(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:4A8F1093024FB814|rigid:i6F8hHfP68NgQR6W6KNHMeBfiPI	false	-	sufficient binding region:21-636	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q8WZ42	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662258|imex:IM-16425-581	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:D548442CD243E7AB|rigid:xZV8c1ZmMjdKg078F3XAjOlEwEA	false	-	sufficient binding region:28640-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:P0CG47	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697|ensembl:ENSP00000379178|ensembl:ENSP00000379180|ensembl:ENSP00000478771	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662277|imex:IM-16425-582	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG47|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|rcsb pdb:2KHW|rcsb pdb:2MBB|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2MRO|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|rcsb pdb:2MSG|go:"GO:1901214"(regulation of neuron death)|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|interpro:IPR000626(Ubiquitin)|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7CAP|rcsb pdb:7JMS|rcsb pdb:7LYC|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-174178|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-983168|reactome:R-HSA-8852276|reactome:R-HSA-8941858|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8856828|reactome:R-HSA-8951664|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|ensembl:ENSG00000170315(gene)|ensembl:ENST00000302182(transcript)|ensembl:ENST00000395837(transcript)|ensembl:ENST00000395839(transcript)|ensembl:ENST00000614404(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|genbank_protein_gi:22538474(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606	intact-crc:723D09BBEF7DD85A|rigid:QM1C0d8euodjKPF2N+20rfmXaRk	false	-	sufficient binding region:9-229	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:P0CG47	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697|ensembl:ENSP00000379178|ensembl:ENSP00000379180|ensembl:ENSP00000478771	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662294|imex:IM-16425-583	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG47|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|rcsb pdb:2KHW|rcsb pdb:2MBB|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2MRO|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|rcsb pdb:2MSG|go:"GO:1901214"(regulation of neuron death)|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|interpro:IPR000626(Ubiquitin)|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7CAP|rcsb pdb:7JMS|rcsb pdb:7LYC|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-174178|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-983168|reactome:R-HSA-8852276|reactome:R-HSA-8941858|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8856828|reactome:R-HSA-8951664|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|ensembl:ENSG00000170315(gene)|ensembl:ENST00000302182(transcript)|ensembl:ENST00000395837(transcript)|ensembl:ENST00000395839(transcript)|ensembl:ENST00000614404(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|genbank_protein_gi:22538474(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606	intact-crc:35EDF26EAC97D1FC|rigid:QM1C0d8euodjKPF2N+20rfmXaRk	false	-	sufficient binding region:97-229..229	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0CG48	uniprotkb:Q96CV9	intact:EBI-3390054|ensembl:ENSP00000344818|ensembl:ENSP00000441543|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662311|imex:IM-16425-584	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5656121|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9613829|ensembl:ENSG00000150991(gene)|ensembl:ENST00000339647(transcript)|ensembl:ENST00000536769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:1ZO6|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|interpro:IPR000626(Ubiquitin)|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2MI8|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3PTF|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6EQI|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7K6P|rcsb pdb:7K6Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|refseq:NP_066289.3|genbank_protein_gi:2647407(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:8F068260B9F5AE55|rigid:8CKCylV+b34Mdon9P+UzgoHgnek	false	sufficient binding region:83-685	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55072	uniprotkb:Q96CV9	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662328|imex:IM-16425-585	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N|genbank_protein_gi:7669552(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:D2D6AA72FEBFD20B|rigid:JrTNPh8p0F/NtabXJBvBTUG6JzY	false	sufficient binding region:472-806	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04275	uniprotkb:Q96CV9	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662345|imex:IM-16425-586	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|genbank_protein_gi:89191867(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:B2E04D84BD9740BD|rigid:nQFg8NSl3CKXDWZft0+Q4pHJKHw	false	sufficient binding region:887-2813	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q2M3W8	uniprotkb:Q96CV9	intact:EBI-2799545|uniprotkb:Q49A75|uniprotkb:B7ZKX3|ensembl:ENSP00000420727	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:zn181_human(display_long)|uniprotkb:HHZ181(gene name synonym)|uniprotkb:ZNF181(gene name)|psi-mi:ZNF181(display_short)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662362|imex:IM-16425-587	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001025168.2|refseq:NP_001139137.1|refseq:XP_005258906.1|refseq:XP_005258907.1|ensembl:ENST00000492450(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|ensembl:ENSG00000197841(gene)|refseq:XP_006723246.1|refseq:XP_016882228.1|genbank_protein_gi:71725372(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:SFrARUqT2wuf7rbUcEU8SqYXZiA9606	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:ABDBCD376589F881|rigid:SooP3H/Z9MRAfCS44X0J7b9QjOo	false	sufficient binding region:240-571(IPR003656)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q9NR11	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-3916142|uniprotkb:Q9P0J4|uniprotkb:Q9BZD8|uniprotkb:Q658J3	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:zn302_human(display_long)|uniprotkb:ZNF302(gene name)|psi-mi:ZNF302(display_short)|uniprotkb:ZNF135L(gene name synonym)|uniprotkb:ZNF140L(gene name synonym)|uniprotkb:ZNF327(gene name synonym)|uniprotkb:Zinc finger protein 135-like(gene name synonym)|uniprotkb:Zinc finger protein 140-like(gene name synonym)|uniprotkb:Zinc finger protein 327(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662380|imex:IM-16425-588	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|reactome:R-HSA-212436|interpro:IPR036051|interpro:IPR036236|refseq:NP_001012320.1|refseq:NP_060913.2|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001276116.1|refseq:NP_001276117.1|refseq:NP_001276118.1|refseq:NP_001276110.1|refseq:NP_001276111.1|refseq:NP_001276119.1|refseq:NP_001276112.1|refseq:NP_001276113.1|refseq:NP_001276120.1|refseq:NP_001276114.1|refseq:NP_001276115.1|refseq:NP_001276121.1|refseq:NP_061145.2|mint:Q9NR11|genbank_protein_gi:59850750(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:FihdHXyOLfG5HUdPhyThDDsJHkA9606	intact-crc:BD33B4E41FF878BC|rigid:gvFdLKJYiD9c4l8heR8UEIGB/I8	false	-	sufficient binding region:255-478(IPR007087)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q9BUY5	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-743265|ensembl:ENSP00000253115|ensembl:ENSP00000439017|uniprotkb:B3KTL2	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:zn426_human(display_long)|uniprotkb:ZNF426(gene name)|psi-mi:ZNF426(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662398|imex:IM-16425-589	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:NP_077011.1|ensembl:ENSG00000130818(gene)|ensembl:ENST00000253115(transcript)|ensembl:ENST00000535489(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001304984.1|refseq:NP_001304985.1|genbank_protein_gi:13129115(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:QPI15/Fod+FtlArvKKNMPGSu3zQ9606	intact-crc:7A37950201815EE6|rigid:26gFAmVLzs2i4/vEtf7xkjra7dw	false	-	sufficient binding region:199-554(IPR007087)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:Q9Y462	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-2849152|uniprotkb:Q9Y4J6|uniprotkb:Q6NX42|uniprotkb:B4DSV4|ensembl:ENSP00000276123|ensembl:ENSP00000362260	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:zn711_human(display_long)|uniprotkb:ZNF711(gene name)|psi-mi:ZNF711(display_short)|uniprotkb:CMPX1(gene name synonym)|uniprotkb:ZNF6(gene name synonym)|uniprotkb:Zinc finger protein 6(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662416|imex:IM-16425-590	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank_protein_gi:56549110(identity)	refseq:XP_011529326.1|refseq:XP_011529328.1|refseq:NP_068838.3|refseq:XP_005262243.1|refseq:XP_005262244.1|refseq:XP_005262245.1|refseq:XP_005262246.1|refseq:NP_001317503.1|refseq:XP_016885294.1|refseq:XP_016885295.1|refseq:XP_016885296.1|refseq:XP_016885297.1|refseq:XP_016885298.1|ensembl:ENSG00000147180(gene)|ensembl:ENST00000276123(transcript)|ensembl:ENST00000373165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR006794(Zfx / Zfy transcription activation region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|genbank_protein_gi:95147562(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:+D8I1UK1AkHcgA4oKgk04+/Spvg9606	intact-crc:BB7AF2BA6A5527D4|rigid:NCkZSE6Hf6jpvOP+aGoT5OnTAPI	false	-	sufficient binding region:306-761	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53GG5	uniprotkb:P35609	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662433|imex:IM-16425-591	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	intact-crc:63787560AD394156|rigid:2GV/f8NkWFNKPxi0J3UmfMlStFc	false	sufficient binding region:123-341	sufficient binding region:402-894(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBF9	uniprotkb:Q53GG5	intact:EBI-296701|uniprotkb:A0A4R6|uniprotkb:B4DT79	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	psi-mi:myoti_human(display_long)|uniprotkb:MYOT(gene name)|psi-mi:MYOT(display_short)|uniprotkb:TTID(gene name synonym)|uniprotkb:Titin immunoglobulin domain protein(gene name synonym)|uniprotkb:Myofibrillar titin-like Ig domains protein(gene name synonym)|uniprotkb:57 kDa cytoskeletal protein(gene name synonym)	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662451|imex:IM-16425-592	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030424"(axon)|go:"GO:0042383"(sarcolemma)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050808"(synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0030018"(Z disc)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001129412.1|refseq:NP_006781.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|rcsb pdb:2KDG|rcsb pdb:2KKQ|refseq:NP_001287840.1|interpro:IPR036179|genbank_protein_gi:5803105(identity)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:y7p/HY416pf0hNjpo0B5cRolBAk9606	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	intact-crc:68C48A33067593E3|rigid:51VPuI2vPFkJoc2E3n4KTiikgmw	false	sufficient binding region:387-498..498(IPR007110)	sufficient binding region:1-110	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPC6	uniprotkb:Q53GG5	intact:EBI-746712|uniprotkb:O43415|uniprotkb:Q9HB92|ensembl:ENSP00000306997	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	psi-mi:myoz2_human(display_long)|uniprotkb:Calsarcin-1(gene name synonym)|uniprotkb:FATZ-related protein 2(gene name synonym)|uniprotkb:MYOZ2(gene name)|psi-mi:MYOZ2(display_short)|uniprotkb:C4orf5(gene name synonym)	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662469|imex:IM-16425-593	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057683.1|ensembl:ENSG00000172399(gene)|ensembl:ENST00000307128(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003779"(actin binding)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031433"(telethonin binding)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051373"(FATZ binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR008438(Calcineurin-binding)|genbank_protein_gi:19923486(identity)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Y2B5tDM2oGscI8xiTwB69hFEhL89606	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	intact-crc:82C17E2D2B65F8B5|rigid:A6lcRk0eYC7FeTVOOxJJ4q6kEnc	false	sufficient binding region:156-264..264(IPR008438)	sufficient binding region:1-110	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TDC0	uniprotkb:Q53GG5	intact:EBI-5662487|uniprotkb:D3DQG9|uniprotkb:B2R9Q4|uniprotkb:Q8IVN1|uniprotkb:Q8IVM1|ensembl:ENSP00000297130|ensembl:ENSP00000428815	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	psi-mi:myoz3_human(display_long)|uniprotkb:Calsarcin-3(gene name synonym)|uniprotkb:FATZ-related protein 3(gene name synonym)|uniprotkb:FRP3(gene name synonym)|uniprotkb:MYOZ3(gene name)|psi-mi:MYOZ3(display_short)	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662494|imex:IM-16425-594	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001116325.1|refseq:NP_588612.2|ensembl:ENSG00000164591(gene)|ensembl:ENST00000297130(transcript)|ensembl:ENST00000517768(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0031433"(telethonin binding)|go:"GO:0051373"(FATZ binding)|interpro:IPR008438(Calcineurin-binding)|genbank_protein_gi:31377622(identity)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:jyYhB/mp2dLVrqa/S9/hglvndrM9606	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	intact-crc:D3281E0D4F01F39B|rigid:phPNgun3BkhQAjS2ynnQfsrpWl8	false	sufficient binding region:236-251..251(IPR008438)	sufficient binding region:1-110	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86TC9	uniprotkb:Q53GG5	intact:EBI-2562606|uniprotkb:Q5VV35|uniprotkb:Q8N3L4|uniprotkb:Q5VV36|uniprotkb:Q96K90|uniprotkb:Q96KF5|uniprotkb:Q86T37|ensembl:ENSP00000351790|ensembl:ENSP00000441668	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	psi-mi:mypn_human(display_long)|uniprotkb:MYPN(gene name)|psi-mi:MYPN(display_short)|uniprotkb:MYOP(gene name synonym)|uniprotkb:145 kDa sarcomeric protein(gene name synonym)	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662512|imex:IM-16425-595	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000354393|ensembl:ENSP00000346369|ensembl:ENSP00000351790|ensembl:ENSP00000441668|refseq:NP_115967.2|interpro:IPR036179|mint:Q86TC9|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000138347(gene)|ensembl:ENST00000358913(transcript)|ensembl:ENST00000540630(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|refseq:NP_001243196.1|refseq:XP_016872323.1|genbank_protein_gi:14211894(identity)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:kWrDyujf/fnKN+I9jI49iO+NIGs9606	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	intact-crc:1DB5F25E100EE130|rigid:78YQHr77xVs+iRQw+Ay02jPQzMM	false	sufficient binding region:1278-1320..1320	sufficient binding region:1-110	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WX93	uniprotkb:Q53GG5	intact:EBI-2803991|uniprotkb:Q9Y2J6|uniprotkb:Q9UQF5|uniprotkb:Q8N1M2|uniprotkb:Q7Z3W0|uniprotkb:Q86WE8|uniprotkb:B5MD56|uniprotkb:Q7L3E0|uniprotkb:Q9UGA0|uniprotkb:Q9Y3E9|uniprotkb:B7ZMM5|uniprotkb:B3KTG2	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	psi-mi:palld_human(display_long)|uniprotkb:KIAA0992(gene name synonym)|uniprotkb:SIH002(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-77(gene name synonym)|uniprotkb:CGI-151(orf name)|uniprotkb:PALLD(gene name)|psi-mi:PALLD(display_short)	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662529|imex:IM-16425-596	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR033017|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0060076"(excitatory synapse)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|rcsb pdb:2DM2|rcsb pdb:2DM3|go:"GO:0016477"(cell migration)|refseq:NP_001159580.1|refseq:NP_001159581.1|refseq:NP_001159582.1|refseq:NP_057165.3|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR036179|mint:Q8WX93|genbank_protein_gi:93102360(identity)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0GUVyoDYzf03b+bZXUa1n/fnP/Y9606	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	intact-crc:009AE450F37ACE0E|rigid:0+eQOeWiiIl+/2f31O34NmF2hnc	false	sufficient binding region:1090-1383(IPR007110)	sufficient binding region:1-110	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53GG5	uniprotkb:Q53GG5	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662547|imex:IM-16425-597	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:7656882(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	intact-crc:965CA0B5D7E0A49D|rigid:LSJH11Ti2BfxU8Y/AdoV4UxmQmA	false	sufficient binding region:123-341	sufficient binding region:329-364..364	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49792	uniprotkb:Q53GG5	intact:EBI-973138|intact:EBI-28970106|ensembl:ENSP00000283195|uniprotkb:Q13074|uniprotkb:Q15280|uniprotkb:Q53TE2|uniprotkb:Q59FH7	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	psi-mi:rbp2_human(display_long)|uniprotkb:RANBP2(gene name)|psi-mi:RANBP2(display_short)|uniprotkb:NUP358(gene name synonym)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup358(gene name synonym)|uniprotkb:Nucleoporin Nup358(gene name synonym)|uniprotkb:358 kDa nucleoporin(gene name synonym)|uniprotkb:p270(gene name synonym)	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662564|imex:IM-16425-598	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000153201(gene)|ensembl:ENST00000283195(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006457"(protein folding)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|reactome:R-HSA-168271|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|mint:P49792|reactome:R-HSA-168276|rcsb pdb:1RRP|reactome:R-HSA-168325|reactome:R-HSA-168333|rcsb pdb:1XKE|rcsb pdb:1Z5S|rcsb pdb:2LAS|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4GA0|rcsb pdb:4I9Y|rcsb pdb:4L6E|rcsb pdb:4LQW|rcsb pdb:5CLL|rcsb pdb:5CLQ|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-170822|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-180746|reactome:R-HSA-9648025|ensembl:ENSP00000283195|refseq:NP_006258.3|dip:DIP-37654N|genbank_protein_gi:19718756(identity)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KB+rjfw8djVygvDpTncA0NO2MDY9606	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	intact-crc:6EB0753E1D8B5AF7|rigid:j5kSMaR37yI1MiyYWwtlYhke8jI	false	sufficient binding region:1030-3224	sufficient binding region:123-341	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49792	uniprotkb:Q53GG5	intact:EBI-973138|intact:EBI-28970106|ensembl:ENSP00000283195|uniprotkb:Q13074|uniprotkb:Q15280|uniprotkb:Q53TE2|uniprotkb:Q59FH7	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	psi-mi:rbp2_human(display_long)|uniprotkb:RANBP2(gene name)|psi-mi:RANBP2(display_short)|uniprotkb:NUP358(gene name synonym)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup358(gene name synonym)|uniprotkb:Nucleoporin Nup358(gene name synonym)|uniprotkb:358 kDa nucleoporin(gene name synonym)|uniprotkb:p270(gene name synonym)	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662581|imex:IM-16425-599	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000153201(gene)|ensembl:ENST00000283195(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006457"(protein folding)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|reactome:R-HSA-168271|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|mint:P49792|reactome:R-HSA-168276|rcsb pdb:1RRP|reactome:R-HSA-168325|reactome:R-HSA-168333|rcsb pdb:1XKE|rcsb pdb:1Z5S|rcsb pdb:2LAS|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4GA0|rcsb pdb:4I9Y|rcsb pdb:4L6E|rcsb pdb:4LQW|rcsb pdb:5CLL|rcsb pdb:5CLQ|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-170822|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-180746|reactome:R-HSA-9648025|ensembl:ENSP00000283195|refseq:NP_006258.3|dip:DIP-37654N|genbank_protein_gi:19718756(identity)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KB+rjfw8djVygvDpTncA0NO2MDY9606	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	intact-crc:C570AF83DFBF2FA2|rigid:j5kSMaR37yI1MiyYWwtlYhke8jI	false	sufficient binding region:2009-3224	sufficient binding region:123-341	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49792	uniprotkb:Q53GG5	intact:EBI-973138|intact:EBI-28970106|ensembl:ENSP00000283195|uniprotkb:Q13074|uniprotkb:Q15280|uniprotkb:Q53TE2|uniprotkb:Q59FH7	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	psi-mi:rbp2_human(display_long)|uniprotkb:RANBP2(gene name)|psi-mi:RANBP2(display_short)|uniprotkb:NUP358(gene name synonym)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup358(gene name synonym)|uniprotkb:Nucleoporin Nup358(gene name synonym)|uniprotkb:358 kDa nucleoporin(gene name synonym)|uniprotkb:p270(gene name synonym)	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662598|imex:IM-16425-600	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000153201(gene)|ensembl:ENST00000283195(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006457"(protein folding)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|reactome:R-HSA-168271|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|mint:P49792|reactome:R-HSA-168276|rcsb pdb:1RRP|reactome:R-HSA-168325|reactome:R-HSA-168333|rcsb pdb:1XKE|rcsb pdb:1Z5S|rcsb pdb:2LAS|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4GA0|rcsb pdb:4I9Y|rcsb pdb:4L6E|rcsb pdb:4LQW|rcsb pdb:5CLL|rcsb pdb:5CLQ|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-170822|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-180746|reactome:R-HSA-9648025|ensembl:ENSP00000283195|refseq:NP_006258.3|dip:DIP-37654N|genbank_protein_gi:19718756(identity)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KB+rjfw8djVygvDpTncA0NO2MDY9606	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	intact-crc:23BB05B9FEFAC55C|rigid:j5kSMaR37yI1MiyYWwtlYhke8jI	false	sufficient binding region:2269-3224	sufficient binding region:123-341	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21817	uniprotkb:Q53GG5	intact:EBI-1221290|uniprotkb:Q16314|uniprotkb:Q16368|uniprotkb:Q9NPK1|uniprotkb:Q9P1U4|ensembl:ENSP00000352608	intact:EBI-5658852|ensembl:ENSP00000284767|uniprotkb:O60439|uniprotkb:O43590|uniprotkb:O60440|uniprotkb:B2R866|uniprotkb:Q9BVP4|uniprotkb:Q8N6Y6	psi-mi:ryr1_human(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:RYDR(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym)	psi-mi:pdli3_human(display_long)|uniprotkb:ALP(gene name synonym)|uniprotkb:Actinin-associated LIM protein(gene name synonym)|uniprotkb:Alpha-actinin-2-associated LIM protein(gene name synonym)|uniprotkb:PDLIM3(gene name)|psi-mi:PDLIM3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662615|imex:IM-16425-601	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000531.2|refseq:NP_001036188.1|dip:DIP-29708N|ensembl:ENSG00000196218(gene)|ensembl:ENST00000359596(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031674"(I band)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:6UHI|rcsb pdb:6UHS|reactome:R-HSA-2672351|reactome:R-HSA-5578775|genbank_protein_gi:113204616(identity)	ensembl:ENSG00000154553(gene)|ensembl:ENST00000284767(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|refseq:NP_001107579.1|refseq:NP_055291.2|genbank_protein_gi:20379874(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:WHlPtd5++5f+9GX0IGshsqJCOTg9606	rogid:3TmZ/oaKbpr9+pdY4YuiP1nkP1o9606	intact-crc:8529D6A1D4F3EB97|rigid:lHIerO9hJOaAmMIP4mj7oANpV00	false	sufficient binding region:1405-5038	sufficient binding region:123-341	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y244	uniprotkb:P54253	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	intact:EBI-930964|uniprotkb:Q17S02|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|ensembl:ENSP00000244769|ensembl:ENSP00000416360	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662632|imex:IM-16425-602	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	refseq:NP_000323.2|refseq:NP_001121636.1|dip:DIP-35353N|ensembl:ENSG00000124788(gene)|ensembl:ENST00000244769(transcript)|ensembl:ENST00000436367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016363"(nuclear matrix)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035176"(social behavior)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051168"(nuclear export)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR036096|interpro:IPR040172|interpro:IPR043404|mint:P54253|rcsb pdb:1OA8|rcsb pdb:2M41|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6QIU|genbank_protein_gi:51479157(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606	intact-crc:7E135F31C4C6FEA5|rigid:me4N60zi9f6kO8O1VAOrRLxD6Us	false	sufficient binding region:1-141	sufficient binding region:599-815(IPR003652)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H993	uniprotkb:Q9Y244	intact:EBI-1046033|uniprotkb:Q96FC6|uniprotkb:Q9UFY5|ensembl:ENSP00000356263	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	psi-mi:armt1_human(display_long)|uniprotkb:Protein-glutamate O-methyltransferase(gene name synonym)|uniprotkb:Sugar phosphate phosphatase ARMT1(gene name synonym)|uniprotkb:ARMT1(gene name)|psi-mi:ARMT1(display_short)|uniprotkb:Acidic residue methyltransferase 1(gene name synonym)|uniprotkb:C6orf211(gene name synonym)	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662650|imex:IM-16425-603	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273491.1|refseq:NP_078849.1|ensembl:ENSG00000146476(gene)|ensembl:ENST00000367294(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051998"(protein carboxyl O-methyltransferase activity)|go:"GO:0097023"(fructose 6-phosphate aldolase activity)|go:"GO:0103026"(fructose-1-phosphatase activity)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR002791(Protein of unknown function DUF89)|interpro:IPR036075|interpro:IPR039763|mint:Q9H993|rcsb pdb:6UMQ|rcsb pdb:6UMR|genbank_protein_gi:13375745(identity)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:FeUJobBbT9Cnaz/galKMPqF0LIQ9606	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	intact-crc:3D3F09ED7723CFD7|rigid:nvMUcFsDNBmqvSKGEOQLIEkmHAg	false	sufficient binding region:152-441(IPR002791)	sufficient binding region:1-141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y244	uniprotkb:P21695	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	intact:EBI-713346|uniprotkb:Q8N1B0|ensembl:ENSP00000301149|uniprotkb:F8W1L5	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:gpda_human(display_long)|uniprotkb:GPD1(gene name)|psi-mi:GPD1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662668|imex:IM-16425-604	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	refseq:NP_005267.2|ensembl:ENST00000301149(transcript)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0004368"("glycerol-3-phosphate dehydrogenase (quinone) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006116"(NADH oxidation)|go:"GO:0006127"(glycerophosphate shuttle)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0046486"(glycerolipid metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|rcsb pdb:1WPQ|rcsb pdb:1X0V|rcsb pdb:1X0X|rcsb pdb:6E8Y|rcsb pdb:6E8Z|rcsb pdb:6E90|ensembl:ENSG00000167588(gene)|rcsb pdb:6PYP|reactome:R-HSA-1483166|refseq:NP_001244128.1|genbank_protein_gi:33695087(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	rogid:UkxXhZxDnOmPcyeXK53JZO2QJsY9606	intact-crc:721DF886068F2F14|rigid:2JCXmmZzzqDENMZ6m+lRXZX3Crg	false	sufficient binding region:1-141	sufficient binding region:1-349(IPR006168)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60662	uniprotkb:Q9Y244	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662686|imex:IM-16425-605	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:33873545(identity)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	intact-crc:0F68FB4848D53A9E|rigid:uJrRswAfTS90Q7OZiuG+B7BjBoA	false	sufficient binding region:345-606..606(IPR006652)	sufficient binding region:1-141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y244	uniprotkb:O60333	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|ensembl:ENSP00000366290|ensembl:ENSP00000502065|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662704|imex:IM-16425-606	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	ensembl:ENSG00000054523(gene)|ensembl:ENST00000377086(transcript)|ensembl:ENST00000676179(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N|genbank_protein_gi:41393558(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606	intact-crc:061FD7C373D6836C|rigid:E/pW4mnKyxZyCk6K5+morMd30rk	false	sufficient binding region:1-141	sufficient binding region:489-1816	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11217	uniprotkb:Q9Y244	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662721|imex:IM-16425-607	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	intact-crc:E1CC3B35FABBC3F4|rigid:Bmd9VYv/UBW2iMbMX2lYNZmygjU	false	sufficient binding region:223-842(IPR000811)	sufficient binding region:1-141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52756	uniprotkb:Q9Y244	intact:EBI-714003|uniprotkb:Q93021|uniprotkb:Q9BU14|uniprotkb:Q9UKY8|uniprotkb:Q9UL24|ensembl:ENSP00000343054|uniprotkb:B2RA45|uniprotkb:B4DM16|uniprotkb:B4DMF9|uniprotkb:B4DZ63|uniprotkb:Q9HDA6|intact:EBI-16431417	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	psi-mi:rbm5_human(display_long)|uniprotkb:RNA-binding motif protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor LUCA15(gene name synonym)|uniprotkb:Protein G15(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-9(gene name synonym)|uniprotkb:RBM5(gene name)|psi-mi:RBM5(display_short)|uniprotkb:H37(orf name)|uniprotkb:LUCA15(orf name)	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662739|imex:IM-16425-608	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000003756(gene)|ensembl:ENST00000347869(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033094|interpro:IPR034991|interpro:IPR034993|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P52756|rcsb pdb:2LK0|rcsb pdb:2LK1|rcsb pdb:2LKZ|rcsb pdb:5MF9|rcsb pdb:5MFY|reactome:R-HSA-72163|refseq:NP_005769.1|refseq:XP_016860992.1|dip:DIP-47277N|genbank_protein_gi:5032030(identity)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LsPTpaKrGY2xtpYofHbFVXjSi/A9606	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	intact-crc:6BBAD2CF98CEC7B3|rigid:oNO0aBbL1pDXx+HQwhkDYz1zaGs	false	sufficient binding region:71-815(IPR001876)	sufficient binding region:1-141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51571	uniprotkb:Q9Y244	intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym)	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662758|imex:IM-16425-609	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339|genbank_protein_gi:5454089(identity)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	intact-crc:B87FBF5C76C8322F|rigid:DzM4Y1g+4iEQkwoSZRD+Fx0BsN8	false	sufficient binding region:50-173(IPR008855)	sufficient binding region:1-141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q9Y244	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662776|imex:IM-16425-610	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	intact-crc:78180D48FA61D8BE|rigid:507fgjNtp9n0pFk31U4nBMKyHUo	false	sufficient binding region:32869-34350(IPR007110)	sufficient binding region:1-141	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y244	uniprotkb:P18206	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662794|imex:IM-16425-611	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|genbank_protein_gi:15680037(identity)	refseq:NP_003364.1|refseq:NP_054706.1|ensembl:ENSG00000035403(gene)|ensembl:ENST00000211998(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|go:"GO:0005198"(structural molecule activity)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043297"(apical junction assembly)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048675"(axon extension)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|ensembl:ENSP00000211998|ensembl:ENST00000372755|ensembl:ENSP00000361841|dip:DIP-35570N|genbank_protein_gi:50593538(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:E4F52384243E88F9|rigid:2H14kZ0MhjL4sP8TBGoAowANtLY	false	sufficient binding region:1-141	sufficient binding region:189-1134(IPR006077)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15149	uniprotkb:Q86XI6	intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|ensembl:ENSP00000323856|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763	intact:EBI-3918864|ensembl:ENSP00000308318|ensembl:ENSP00000428642|ensembl:ENSP00000493491|ensembl:ENSP00000494659|uniprotkb:Q9H812|uniprotkb:B3KTV3	psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:ppr3b_human(display_long)|uniprotkb:PPP1R3B(gene name)|psi-mi:PPP1R3B(display_short)|uniprotkb:PPP1R4(gene name synonym)|uniprotkb:Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 4(gene name synonym)|uniprotkb:Protein phosphatase 1 subunit GL(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662813|imex:IM-16425-612	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|interpro:IPR030269|interpro:IPR035915|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|ensembl:ENST00000436759|ensembl:ENSP00000388180|ensembl:ENST00000527096|ensembl:ENSP00000434583|ensembl:ENSP00000323856|ensembl:ENST00000345136|ensembl:ENSP00000344848|ensembl:ENST00000354589|ensembl:ENSP00000346602|ensembl:ENST00000354958|ensembl:ENSP00000347044|ensembl:ENST00000356346|ensembl:ENSP00000348702|ensembl:ENST00000357649|ensembl:ENSP00000350277|ensembl:ENST00000398774|ensembl:ENSP00000381756|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1|genbank_protein_gi:117168249(identity)	ensembl:ENSG00000173281(gene)|ensembl:ENSG00000285343(gene)|ensembl:ENST00000310455(transcript)|ensembl:ENST00000519699(transcript)|ensembl:ENST00000644687(transcript)|ensembl:ENST00000645121(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0042587"(glycogen granule)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050196"([phosphorylase] phosphatase activity)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR017434(Protein phosphatase 1, glycogen targeting subunit, Metazoa.)|interpro:IPR030682|interpro:IPR038175|rcsb pdb:2EEF|rcsb pdb:5ZT0|refseq:NP_001188258.1|refseq:NP_078883.2|refseq:XP_006716316.1|refseq:XP_016869324.1|genbank_protein_gi:13375814(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606	rogid:orhf/0MSEUfycwPk+D9BN8A6Ld89606	intact-crc:2FAFB41C13F9212E|rigid:7rUTbEGIDD33kQejqDJjgnWLp9c	false	sufficient binding region:2092-4684	sufficient binding region:1-285	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62140	uniprotkb:Q86XI6	intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769	intact:EBI-3918864|ensembl:ENSP00000308318|ensembl:ENSP00000428642|ensembl:ENSP00000493491|ensembl:ENSP00000494659|uniprotkb:Q9H812|uniprotkb:B3KTV3	psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short)	psi-mi:ppr3b_human(display_long)|uniprotkb:PPP1R3B(gene name)|psi-mi:PPP1R3B(display_short)|uniprotkb:PPP1R4(gene name synonym)|uniprotkb:Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 4(gene name synonym)|uniprotkb:Protein phosphatase 1 subunit GL(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662830|imex:IM-16425-613	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N|genbank_protein_gi:46249375(identity)	ensembl:ENSG00000173281(gene)|ensembl:ENSG00000285343(gene)|ensembl:ENST00000310455(transcript)|ensembl:ENST00000519699(transcript)|ensembl:ENST00000644687(transcript)|ensembl:ENST00000645121(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0042587"(glycogen granule)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050196"([phosphorylase] phosphatase activity)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR017434(Protein phosphatase 1, glycogen targeting subunit, Metazoa.)|interpro:IPR030682|interpro:IPR038175|rcsb pdb:2EEF|rcsb pdb:5ZT0|refseq:NP_001188258.1|refseq:NP_078883.2|refseq:XP_006716316.1|refseq:XP_016869324.1|genbank_protein_gi:13375814(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606	rogid:orhf/0MSEUfycwPk+D9BN8A6Ld89606	intact-crc:E58558F78FC80A2F|rigid:RXdO7JPV71SoGwrApHSIJ5J3/cU	false	sufficient binding region:5-327..327(IPR006186)	sufficient binding region:1-285	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15435	uniprotkb:P11055	intact:EBI-1024281|uniprotkb:Q9UQE5|uniprotkb:Q9UQE6|uniprotkb:Q9Y6K4|ensembl:ENSP00000234038|uniprotkb:B4DFD4|ensembl:ENSP00000385657|uniprotkb:B5MCY6	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	psi-mi:pp1r7_human(display_long)|uniprotkb:Protein phosphatase 1 regulatory subunit 22(gene name synonym)|uniprotkb:PPP1R7(gene name)|psi-mi:PPP1R7(display_short)|uniprotkb:SDS22(gene name synonym)	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662849|imex:IM-16425-614	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115685(gene)|refseq:NP_002703.1|ensembl:ENST00000234038(transcript)|ensembl:ENST00000407025(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|rcsb pdb:6HKW|rcsb pdb:6MKY|rcsb pdb:6OBN|rcsb pdb:6OBP|refseq:NP_001269338.1|refseq:NP_001269339.1|refseq:NP_001269340.1|refseq:NP_001269341.1|refseq:NP_001269342.1|refseq:NP_001269343.1|dip:DIP-1005N|genbank_protein_gi:4506012(identity)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:HKHhTMtEgPpOdf/lS59bZAOrDjk9606	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	intact-crc:F5959AC2E935DE79|rigid:XiEobjrLeySqQdzdbtfO+AZQZG4	false	sufficient binding region:1-360	sufficient binding region:1606-1940	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62140	uniprotkb:Q15435	intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769	intact:EBI-1024281|uniprotkb:Q9UQE5|uniprotkb:Q9UQE6|uniprotkb:Q9Y6K4|ensembl:ENSP00000234038|uniprotkb:B4DFD4|ensembl:ENSP00000385657|uniprotkb:B5MCY6	psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short)	psi-mi:pp1r7_human(display_long)|uniprotkb:Protein phosphatase 1 regulatory subunit 22(gene name synonym)|uniprotkb:PPP1R7(gene name)|psi-mi:PPP1R7(display_short)|uniprotkb:SDS22(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662866|imex:IM-16425-615	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N|genbank_protein_gi:46249375(identity)	ensembl:ENSG00000115685(gene)|refseq:NP_002703.1|ensembl:ENST00000234038(transcript)|ensembl:ENST00000407025(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|rcsb pdb:6HKW|rcsb pdb:6MKY|rcsb pdb:6OBN|rcsb pdb:6OBP|refseq:NP_001269338.1|refseq:NP_001269339.1|refseq:NP_001269340.1|refseq:NP_001269341.1|refseq:NP_001269342.1|refseq:NP_001269343.1|dip:DIP-1005N|genbank_protein_gi:4506012(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606	rogid:HKHhTMtEgPpOdf/lS59bZAOrDjk9606	intact-crc:D99270CF67B18FEA|rigid:r8cmH+334bBTlLGE1YBSCSXz2Zo	false	sufficient binding region:4-327(IPR006186)	sufficient binding region:1-360	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15435	uniprotkb:P36873	intact:EBI-1024281|uniprotkb:Q9UQE5|uniprotkb:Q9UQE6|uniprotkb:Q9Y6K4|ensembl:ENSP00000234038|uniprotkb:B4DFD4|ensembl:ENSP00000385657|uniprotkb:B5MCY6	intact:EBI-356283|ensembl:ENSP00000335084	psi-mi:pp1r7_human(display_long)|uniprotkb:Protein phosphatase 1 regulatory subunit 22(gene name synonym)|uniprotkb:PPP1R7(gene name)|psi-mi:PPP1R7(display_short)|uniprotkb:SDS22(gene name synonym)	psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662884|imex:IM-16425-616	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115685(gene)|refseq:NP_002703.1|ensembl:ENST00000234038(transcript)|ensembl:ENST00000407025(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|rcsb pdb:6HKW|rcsb pdb:6MKY|rcsb pdb:6OBN|rcsb pdb:6OBP|refseq:NP_001269338.1|refseq:NP_001269339.1|refseq:NP_001269340.1|refseq:NP_001269341.1|refseq:NP_001269342.1|refseq:NP_001269343.1|dip:DIP-1005N|genbank_protein_gi:4506012(identity)	go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N|genbank_protein_gi:4506006(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:HKHhTMtEgPpOdf/lS59bZAOrDjk9606	rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606	intact-crc:A08F8D0D6C90169D|rigid:18BunnC3SNlUyy6O1ZFjjk71vao	false	sufficient binding region:1-360	sufficient binding region:10-323(IPR006186)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z699	uniprotkb:Q15435	intact:EBI-5235340|uniprotkb:B2RPJ8|uniprotkb:Q05D53|uniprotkb:Q8N256|ensembl:ENSP00000299084	intact:EBI-1024281|uniprotkb:Q9UQE5|uniprotkb:Q9UQE6|uniprotkb:Q9Y6K4|ensembl:ENSP00000234038|uniprotkb:B4DFD4|ensembl:ENSP00000385657|uniprotkb:B5MCY6	psi-mi:spre1_human(display_long)|uniprotkb:SPRED1(gene name)|psi-mi:SPRED1(display_short)	psi-mi:pp1r7_human(display_long)|uniprotkb:Protein phosphatase 1 regulatory subunit 22(gene name synonym)|uniprotkb:PPP1R7(gene name)|psi-mi:PPP1R7(display_short)|uniprotkb:SDS22(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662902|imex:IM-16425-617	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689807.1|ensembl:ENSG00000166068(gene)|ensembl:ENST00000299084(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005173"(stem cell factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR000697(EVH1)|interpro:IPR007875(Sprouty)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023337|interpro:IPR041937|mint:Q7Z699|rcsb pdb:3SYX|rcsb pdb:6V65|rcsb pdb:6V6F|reactome:R-HSA-5658442|reactome:R-HSA-5658623|reactome:R-HSA-6802953|genbank_protein_gi:31872018(identity)	ensembl:ENSG00000115685(gene)|refseq:NP_002703.1|ensembl:ENST00000234038(transcript)|ensembl:ENST00000407025(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|rcsb pdb:6HKW|rcsb pdb:6MKY|rcsb pdb:6OBN|rcsb pdb:6OBP|refseq:NP_001269338.1|refseq:NP_001269339.1|refseq:NP_001269340.1|refseq:NP_001269341.1|refseq:NP_001269342.1|refseq:NP_001269343.1|dip:DIP-1005N|genbank_protein_gi:4506012(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:+jGnxx5TP0aeldLkqVGfO8uY2ko9606	rogid:HKHhTMtEgPpOdf/lS59bZAOrDjk9606	intact-crc:B46B1D7DB946098B|rigid:oldHnoML71hH7B05PbX6+SOqTHM	false	sufficient binding region:227-444	sufficient binding region:1-360	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95407	uniprotkb:Q15435	intact:EBI-524171|ensembl:ENSP00000359013	intact:EBI-1024281|uniprotkb:Q9UQE5|uniprotkb:Q9UQE6|uniprotkb:Q9Y6K4|ensembl:ENSP00000234038|uniprotkb:B4DFD4|ensembl:ENSP00000385657|uniprotkb:B5MCY6	psi-mi:tnf6b_human(display_long)|uniprotkb:Decoy receptor for Fas ligand(gene name synonym)|uniprotkb:Decoy receptor 3(gene name synonym)|uniprotkb:M68(gene name synonym)|uniprotkb:UNQ186/PRO212(orf name)|uniprotkb:TNFRSF6B(gene name)|psi-mi:TNFRSF6B(display_short)|uniprotkb:DCR3(gene name synonym)|uniprotkb:TR6(gene name synonym)	psi-mi:pp1r7_human(display_long)|uniprotkb:Protein phosphatase 1 regulatory subunit 22(gene name synonym)|uniprotkb:PPP1R7(gene name)|psi-mi:PPP1R7(display_short)|uniprotkb:SDS22(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662919|imex:IM-16425-618	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003814.1|ensembl:ENSG00000243509(gene)|ensembl:ENST00000369996(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006915"(apoptotic process)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR034023|rcsb pdb:3K51|rcsb pdb:3MHD|rcsb pdb:3MI8|rcsb pdb:4J6G|rcsb pdb:4KGG|rcsb pdb:4KGQ|rcsb pdb:4MSV|rcsb pdb:5L36|reactome:R-HSA-5669034|genbank_protein_gi:29893809(identity)	ensembl:ENSG00000115685(gene)|refseq:NP_002703.1|ensembl:ENST00000234038(transcript)|ensembl:ENST00000407025(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|rcsb pdb:6HKW|rcsb pdb:6MKY|rcsb pdb:6OBN|rcsb pdb:6OBP|refseq:NP_001269338.1|refseq:NP_001269339.1|refseq:NP_001269340.1|refseq:NP_001269341.1|refseq:NP_001269342.1|refseq:NP_001269343.1|dip:DIP-1005N|genbank_protein_gi:4506012(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6TcPTYX4msQy2jsSWmzZFE0+7MY9606	rogid:HKHhTMtEgPpOdf/lS59bZAOrDjk9606	intact-crc:17B80F278A01575F|rigid:LMynXZXPXH65FukKwos1r9CX+n0	false	sufficient binding region:156-300..300(IPR001368)	sufficient binding region:1-360	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11055	uniprotkb:O94806	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	intact:EBI-1255366|uniprotkb:Q53TR7|uniprotkb:Q8NEL8|uniprotkb:D6W587|ensembl:ENSP00000368356|ensembl:ENSP00000234179	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:kpcd3_human(display_long)|uniprotkb:PRKD3(gene name)|psi-mi:PRKD3(display_short)|uniprotkb:EPK2(gene name synonym)|uniprotkb:PRKCN(gene name synonym)|uniprotkb:Protein kinase C nu type(gene name synonym)|uniprotkb:nPKC-nu(gene name synonym)|uniprotkb:Protein kinase EPK2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662937|imex:IM-16425-619	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	refseq:NP_005804.1|refseq:XP_005264294.1|ensembl:ENSG00000115825(gene)|ensembl:ENST00000234179(transcript)|ensembl:ENST00000379066(transcript)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0089700"(protein kinase D signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015727(Protein kinase C mu-related)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|rcsb pdb:2D9Z|reactome:R-HSA-1660661|genbank_protein_gi:48255886(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	rogid:UgwsN9a5nJT53K2HrD1E94A5HWc9606	intact-crc:413A1FBA3F2B0C41|rigid:b1JetHx0ug3KJ/kUparHkuwNXco	false	sufficient binding region:147-1940	sufficient binding region:1-593	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21675	uniprotkb:O94806	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	intact:EBI-1255366|uniprotkb:Q53TR7|uniprotkb:Q8NEL8|uniprotkb:D6W587|ensembl:ENSP00000368356|ensembl:ENSP00000234179	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:kpcd3_human(display_long)|uniprotkb:PRKD3(gene name)|psi-mi:PRKD3(display_short)|uniprotkb:EPK2(gene name synonym)|uniprotkb:PRKCN(gene name synonym)|uniprotkb:Protein kinase C nu type(gene name synonym)|uniprotkb:nPKC-nu(gene name synonym)|uniprotkb:Protein kinase EPK2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662954|imex:IM-16425-620	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N|genbank_protein_gi:20357587(identity)	refseq:NP_005804.1|refseq:XP_005264294.1|ensembl:ENSG00000115825(gene)|ensembl:ENST00000234179(transcript)|ensembl:ENST00000379066(transcript)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0089700"(protein kinase D signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015727(Protein kinase C mu-related)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|rcsb pdb:2D9Z|reactome:R-HSA-1660661|genbank_protein_gi:48255886(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	rogid:UgwsN9a5nJT53K2HrD1E94A5HWc9606	intact-crc:8080981D04E77995|rigid:sSrBWFecOsF82jTpVDif13q8orI	false	sufficient binding region:1047-1872	sufficient binding region:1-593	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929	uniprotkb:Q06124-1	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	intact:EBI-25302300|ensembl:ENSP00000489597	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:q06124-1(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:PTP2Ci(isoform synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662971|imex:IM-16425-621	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	ensembl:ENSG00000179295(gene)|ensembl:ENST00000635625(transcript)|intact:EBI-297779(isoform-parent)|uniprotkb:Q06124-1(isoform-parent)|genbank_protein_gi:33356176(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2020/01/07	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rogid:r55mH5SqYxGrpxM24VrTNWxqOPg9606	intact-crc:1F4D2F22117D8A39|rigid:zJjQhry5gTNr7tCnnZIHOdkLs8c	false	sufficient binding region:5329-6669(IPR000900)	sufficient binding region:1-593	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11217	uniprotkb:Q9UPW5	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	intact:EBI-947297|uniprotkb:Q63HM7|uniprotkb:Q658P5|uniprotkb:Q6P9D6|uniprotkb:Q9H8U6|uniprotkb:Q9H9W8|uniprotkb:Q9NVK1|intact:EBI-2692992|intact:EBI-1104488|uniprotkb:Q5VV80|uniprotkb:B4DIT6|uniprotkb:B4DRZ8|ensembl:ENSP00000349592	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:cbpc1_human(display_long)|uniprotkb:AGTPBP1(gene name)|psi-mi:AGTPBP1(display_short)|uniprotkb:CCP1(gene name synonym)|uniprotkb:KIAA1035(gene name synonym)|uniprotkb:NNA1(gene name synonym)|uniprotkb:ATP/GTP-binding protein 1(gene name synonym)|uniprotkb:Nervous system nuclear protein induced by axotomy protein 1 homolog(gene name synonym)|uniprotkb:Protein deglutamylase CCP1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5662992|imex:IM-16425-622	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	refseq:NP_056054.2|refseq:NP_001273644.1|refseq:NP_001273646.1|refseq:XP_005251905.1|refseq:NP_001317630.1|refseq:XP_016870033.1|refseq:XP_016870035.1|ensembl:ENSG00000135049(gene)|go:"GO:0042133"(neurotransmitter metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098958"(retrograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033852|interpro:IPR040626|reactome:R-HSA-8955332|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015631"(tubulin binding)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0035608"(protein deglutamylation)|go:"GO:0035609"(C-terminal protein deglutamylation)|go:"GO:0035610"(protein side chain deglutamylation)|ensembl:ENST00000357081(transcript)|genbank_protein_gi:38174517(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	rogid:kzq5xb9lQGQbLjWitxmeKnf1zkg9606	intact-crc:77E497BEAC043D62|rigid:lxuVYAmtvNi7TRpgwF+9p5NZQYE	false	sufficient binding region:160-481	sufficient binding region:595-1226	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NFD5	uniprotkb:P11217	intact:EBI-679921|uniprotkb:Q5JRD1|uniprotkb:Q5VYC4|uniprotkb:Q8IZY8|uniprotkb:Q8TEV0|uniprotkb:Q8TF02|uniprotkb:Q99491|uniprotkb:Q9ULI5|intact:EBI-2560572|ensembl:ENSP00000055163	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	psi-mi:ari1b_human(display_long)|uniprotkb:BAF250B(gene name synonym)|uniprotkb:Osa homolog 2(gene name synonym)|uniprotkb:p250R(gene name synonym)|uniprotkb:BRG1-binding protein hELD/OSA1(gene name synonym)|uniprotkb:BRG1-associated factor 250b(gene name synonym)|uniprotkb:ARID1B(gene name)|psi-mi:ARID1B(display_short)|uniprotkb:DAN15(gene name synonym)|uniprotkb:KIAA1235(gene name synonym)|uniprotkb:OSA2(gene name synonym)	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663009|imex:IM-16425-623	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001333742.1|refseq:NP_059989.2|refseq:NP_065783.3|ensembl:ENSG00000049618(gene)|ensembl:ENST00000350026(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR021906|interpro:IPR033388|interpro:IPR036431|interpro:IPR038040|mint:Q8NFD5|rcsb pdb:2CXY|rcsb pdb:2EH9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|genbank_protein_gi:40068461(identity)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:BeWhuwPk5f6HN+yasFEJRpkbM6A9606	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	intact-crc:7648948D81AFB0FB|rigid:D3AXA330AA37uokHeVNWhWEUvlA	false	sufficient binding region:1554-2236	sufficient binding region:160-481	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11217	uniprotkb:Q9Y5S2	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	intact:EBI-1043430|uniprotkb:Q2L7A5|uniprotkb:Q86TJ1|uniprotkb:Q9ULU5|ensembl:ENSP00000355237|uniprotkb:A9JR72	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:mrckb_human(display_long)|uniprotkb:CDC42-binding protein kinase beta(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase beta(gene name synonym)|uniprotkb:DMPK-like beta(gene name synonym)|uniprotkb:CDC42BPB(gene name)|psi-mi:CDC42BPB(display_short)|uniprotkb:KIAA1124(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663026|imex:IM-16425-624	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSG00000198752(gene)|ensembl:ENST00000361246(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR031597|interpro:IPR033232|interpro:IPR042718|rcsb pdb:3QFV|rcsb pdb:3TKU|rcsb pdb:4UAK|rcsb pdb:4UAL|rcsb pdb:5OTE|rcsb pdb:5OTF|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|refseq:NP_006026.3|genbank_protein_gi:115527096(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	rogid:FaheT9htZ/NtYfTKvNDcLqNtQiQ9606	intact-crc:CC345290F99C0525|rigid:B/tzRFx6bbKvTk1LbaBmUz/CSPM	false	sufficient binding region:160-481	sufficient binding region:727-1711	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11217	uniprotkb:O75122	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	intact:EBI-913524|ensembl:ENSP00000417518|uniprotkb:Q7L8F6|uniprotkb:Q8N6R6|uniprotkb:Q9BQT3|uniprotkb:Q9BQT4|uniprotkb:Q9H7A3|uniprotkb:Q9NSZ2|intact:EBI-2514712|uniprotkb:B2RTR1|uniprotkb:F5H604|intact:EBI-10967478	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:clap2_human(display_long)|uniprotkb:CLASP2(gene name)|psi-mi:CLASP2(display_short)|uniprotkb:KIAA0627(gene name synonym)|uniprotkb:Cytoplasmic linker-associated protein 2(gene name synonym)|uniprotkb:Protein Orbit homolog 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663043|imex:IM-16425-625	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	ensembl:ENSG00000163539(gene)|go:"GO:0007030"(Golgi organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0010458"(exit from mitosis)|ensembl:ENST00000480013(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0016020"(membrane)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045180"(basal cortex)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051301"(cell division)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1903754"(cortical microtubule plus-end)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024395|interpro:IPR034085|mint:O75122|rcsb pdb:3WOY|rcsb pdb:5NR4|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-428890|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001193973.1|refseq:NP_055912.2|dip:DIP-36804N|genbank_protein_gi:57863300(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/09/18	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	rogid:FNIEvRFPqFi6NPFLsVHlKvfkN9w9606	intact-crc:BF7149E5D83C0092|rigid:dSi2uisQ8JpneMaoZfb272/Svrc	false	sufficient binding region:160-481	sufficient binding region:773-1294	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50570	uniprotkb:P11217	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663060|imex:IM-16425-626	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|genbank_protein_gi:56549124(identity)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	intact-crc:AE046F8E5E69C4DB|rigid:ExClcRYd5xiU2lxvmvRF517qUUM	false	sufficient binding region:76-870	sufficient binding region:160-481	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQ89	uniprotkb:P11217	intact:EBI-1752811|uniprotkb:D3DVW2|uniprotkb:Q5R1M7|ensembl:ENSP00000246100|ensembl:ENSP00000354163|ensembl:ENSP00000371365|ensembl:ENSP00000371367|ensembl:ENSP00000445228	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	psi-mi:f110a_human(display_long)|uniprotkb:FAM110A(gene name)|psi-mi:FAM110A(display_short)|uniprotkb:C20orf55(gene name synonym)|uniprotkb:F10(gene name synonym)	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663077|imex:IM-16425-627	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011527683.1|refseq:NP_001035812.1|refseq:NP_113612.1|refseq:NP_997004.1|refseq:NP_001276074.1|refseq:NP_001276075.1|refseq:NP_001276076.1|ensembl:ENSG00000125898(gene)|ensembl:ENST00000246100(transcript)|ensembl:ENST00000304189(transcript)|ensembl:ENST00000381939(transcript)|ensembl:ENST00000381941(transcript)|ensembl:ENST00000541082(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|interpro:IPR025739|interpro:IPR025740|interpro:IPR025741|genbank_protein_gi:108389153(identity)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:fwxpzV+6TSnqE7Wl8IjgEswrV9I9606	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	intact-crc:A5EB3F4BC67C4A90|rigid:EkfJdT61faNYQRhVbSOaWhae+no	false	sufficient binding region:247-295..295	sufficient binding region:160-481	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11217	uniprotkb:O75323	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	intact:EBI-307133|uniprotkb:O43801|uniprotkb:Q53X96|uniprotkb:C9IYJ3|ensembl:ENSP00000313050	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:nips2_human(display_long)|uniprotkb:NIPSNAP2(gene name)|psi-mi:NIPSNAP2(display_short)|uniprotkb:GBAS(gene name synonym)|uniprotkb:Glioblastoma-amplified sequence(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663094|imex:IM-16425-628	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	refseq:NP_001189398.1|refseq:NP_001474.1|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:O75323|reactome:R-HSA-9013407|reactome:R-HSA-9013409|ensembl:ENSG00000146729(gene)|ensembl:ENST00000322090(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|dip:DIP-33564N|genbank_protein_gi:30583062(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	rogid:sfBQGdtSVoH21kBu/Bz9x8x3KWU9606	intact-crc:9D9BCC9E8634F8FD|rigid:7qwCw598zbccVcJVixspNWTsh8I	false	sufficient binding region:160-481	sufficient binding region:68-286	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11217	uniprotkb:P78318	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663111|imex:IM-16425-629	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1|genbank_protein_gi:48375183(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	intact-crc:E219B7D16A55AE2A|rigid:777yCWnN/NWT5yw+KSHoNHYE5+Y	false	sufficient binding region:160-481	sufficient binding region:168-339(IPR007304)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HW7	uniprotkb:P11217	intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short)	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663139|imex:IM-16425-630	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505|genbank_protein_gi:50086623(identity)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	intact-crc:F6FD961A677DAF5D|rigid:OvpXs9DwB1vSe3lCysJztGPWAMQ	false	sufficient binding region:370-963(IPR000357)	sufficient binding region:160-481	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P02545	uniprotkb:P11217	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663157|imex:IM-16425-631	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N|genbank_protein_gi:27436944(identity)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	intact-crc:0AAC3819430D4F22|rigid:adGp6JmcvntEFEobCU5OFd9miPU	false	sufficient binding region:240-664(IPR001664)	sufficient binding region:160-481	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VU43	uniprotkb:P11217	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663175|imex:IM-16425-632	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|genbank_protein_gi:50658072(identity)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	intact-crc:40E5F1186DA63B2D|rigid:YBMAgqpt5IXGMG88pnb1Sl/upVI	false	sufficient binding region:489-2346	sufficient binding region:160-481	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11217	uniprotkb:Q86XI6	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	intact:EBI-3918864|ensembl:ENSP00000308318|ensembl:ENSP00000428642|ensembl:ENSP00000493491|ensembl:ENSP00000494659|uniprotkb:Q9H812|uniprotkb:B3KTV3	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:ppr3b_human(display_long)|uniprotkb:PPP1R3B(gene name)|psi-mi:PPP1R3B(display_short)|uniprotkb:PPP1R4(gene name synonym)|uniprotkb:Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 4(gene name synonym)|uniprotkb:Protein phosphatase 1 subunit GL(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663192|imex:IM-16425-633	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	ensembl:ENSG00000173281(gene)|ensembl:ENSG00000285343(gene)|ensembl:ENST00000310455(transcript)|ensembl:ENST00000519699(transcript)|ensembl:ENST00000644687(transcript)|ensembl:ENST00000645121(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0042587"(glycogen granule)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050196"([phosphorylase] phosphatase activity)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR017434(Protein phosphatase 1, glycogen targeting subunit, Metazoa.)|interpro:IPR030682|interpro:IPR038175|rcsb pdb:2EEF|rcsb pdb:5ZT0|refseq:NP_001188258.1|refseq:NP_078883.2|refseq:XP_006716316.1|refseq:XP_016869324.1|genbank_protein_gi:27696644(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	rogid:orhf/0MSEUfycwPk+D9BN8A6Ld89606	intact-crc:5BEF3C947093EFD8|rigid:2C3SORQk8e3xWxxf+gRTZy8RIWU	false	sufficient binding region:160-481	sufficient binding region:114-285..285(IPR005036)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76094	uniprotkb:P11217	intact:EBI-1058850|ensembl:ENSP00000495128|intact:EBI-2654733|uniprotkb:G5E9Z8|uniprotkb:Q7Z3C0	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	psi-mi:srp72_human(display_long)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein(gene name synonym)	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663210|imex:IM-16425-634	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008878.3|refseq:NP_001254651.1|ensembl:ENSG00000174780(gene)|ensembl:ENST00000642900(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR019734|interpro:IPR026270|interpro:IPR031545|mint:O76094|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:5WRW|rcsb pdb:7NFX|reactome:R-HSA-1799339|genbank_protein_gi:109638748(identity)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NJfyOcmKiBWszQsH0EQotsdwhU09606	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	intact-crc:4D7CD7C70B59673A|rigid:D8ITFqQuqOc29DspMo36nxRJe0k	false	sufficient binding region:42-671(IPR001440)	sufficient binding region:160-481	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV2	uniprotkb:P11217	intact:EBI-2130429|uniprotkb:A5D8T7|uniprotkb:Q53SY4|uniprotkb:Q9BYV3|ensembl:ENSP00000369415	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	psi-mi:tri54_human(display_long)|uniprotkb:TRIM54(gene name)|psi-mi:TRIM54(display_short)|uniprotkb:MURF(gene name synonym)|uniprotkb:MURF3(gene name synonym)|uniprotkb:RNF30(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 3(gene name synonym)|uniprotkb:Muscle-specific RING finger protein(gene name synonym)|uniprotkb:RING finger protein 30(gene name synonym)	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663228|imex:IM-16425-635	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115935.3|refseq:NP_912730.2|interpro:IPR027370|interpro:IPR033492|interpro:IPR042752|rcsb pdb:3Q1D|ensembl:ENSG00000138100(gene)|ensembl:ENST00000380075(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|genbank_protein_gi:34878869(identity)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rxNKa4ddkMuN1HQlCnhYo2Ypi589606	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	intact-crc:61A26C21747F2009|rigid:YQfPzLnjdPkmUeRmafph0e409u8	false	sufficient binding region:20-358(IPR001841)	sufficient binding region:160-481	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV6	uniprotkb:P11217	intact:EBI-2341179|uniprotkb:Q96DV3|uniprotkb:Q9BYV5|uniprotkb:Q8IUD9|uniprotkb:Q8IUE4|uniprotkb:Q96DV2|uniprotkb:Q53XX3|uniprotkb:B3KRC0|uniprotkb:B3KRJ3|ensembl:ENSP00000323913	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	psi-mi:tri55_human(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663246|imex:IM-16425-636	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011515915.1|refseq:XP_011515916.1|refseq:XP_011515917.1|refseq:XP_011515918.1|refseq:NP_149047.2|refseq:NP_908973.1|refseq:NP_908974.1|refseq:NP_908975.1|ensembl:ENSG00000147573(gene)|ensembl:ENST00000315962(transcript)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0050904"(diapedesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1905517"(macrophage migration)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR033492|mint:Q9BYV6|genbank_protein_gi:34878843(identity)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:MiXH7mPPLOjav9yf0/HL7neg3yI9606	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	intact-crc:0A42BF4AC95E21EE|rigid:EilH4LSQOOBnhoBLYqi6qh/775k	false	sufficient binding region:1-548(IPR001841)	sufficient binding region:160-481	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11217	uniprotkb:Q8WZ42	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663264|imex:IM-16425-637	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:93B1D3D283441A14|rigid:YILTA1b7UVlMPGzkL1ZO/NoGv3g	false	sufficient binding region:160-481	sufficient binding region:14784-34350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11217	uniprotkb:Q9H0M0	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	intact:EBI-742157|uniprotkb:O00307|uniprotkb:Q96BP4|ensembl:ENSP00000265428|ensembl:ENSP00000427793|uniprotkb:Q5YLC1	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:wwp1_human(display_long)|uniprotkb:WWP1(gene name)|psi-mi:WWP1(display_short)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 5(gene name synonym)|uniprotkb:TGIF-interacting ubiquitin ligase 1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase WWP1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663281|imex:IM-16425-638	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	refseq:NP_008944.1|interpro:IPR035892|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR035983|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR036020|mint:Q9H0M0|rcsb pdb:1ND7|rcsb pdb:2OP7|rcsb pdb:5HPS|rcsb pdb:5HPT|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|rcsb pdb:6J1X|rcsb pdb:6J1Y|reactome:R-HSA-1253288|reactome:R-HSA-2672351|reactome:R-HSA-8939902|reactome:R-HSA-983168|interpro:IPR024928|ensembl:ENSG00000123124(gene)|ensembl:ENST00000265428(transcript)|ensembl:ENST00000517970(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_005250817.1|genbank_protein_gi:33946331(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	rogid:a+aRHHhwu3pCkmlkDNqcN1PJ7LI9606	intact-crc:2A13743F6F207128|rigid:3HHvfaoCNjVRk2JxmIG5dRgq9ww	false	sufficient binding region:160-481	sufficient binding region:697-922..922(IPR000569)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35241	uniprotkb:P61289	intact:EBI-2514878|ensembl:ENSP00000496503|uniprotkb:Q86Y61|uniprotkb:A7YIK0|uniprotkb:A7YIK3|uniprotkb:A7YIJ8|uniprotkb:B7Z9U6|uniprotkb:F5H1A7	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:radi_human(display_long)|uniprotkb:RDX(gene name)|psi-mi:RDX(display_short)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663299|imex:IM-16425-639	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137710(gene)|ensembl:ENST00000645495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:1903392"(negative regulation of adherens junction organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35241|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_002897.1|refseq:NP_001247423.1|refseq:NP_001247424.1|refseq:NP_001247425.1|refseq:NP_001247421.1|refseq:NP_001247422.1|genbank_protein_gi:28436808(identity)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_protein_gi:30410793(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:75lzbINdL0deHtiWY7IwioSh5749606	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:6C6F2AA95AD0694A|rigid:nm/KkDuqRLPzYEMLkIumsgB1USg	false	sufficient binding region:1-583	sufficient binding region:79-254(IPR003186)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96D71	uniprotkb:Q14315	intact:EBI-1171195|uniprotkb:Q9BXY9|uniprotkb:Q8NDR7|uniprotkb:Q8WU62|uniprotkb:Q5JWJ7|uniprotkb:Q5JWJ5|uniprotkb:Q5JWJ6|uniprotkb:B7ZBZ8|uniprotkb:B7ZBZ9|uniprotkb:B7ZC00|uniprotkb:J3KP76|intact:EBI-28972584|ensembl:ENSP00000392065	intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145	psi-mi:reps1_human(display_long)|uniprotkb:REPS1(gene name)|psi-mi:REPS1(display_short)|uniprotkb:RalBP1-interacting protein 1(gene name synonym)	psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663317|imex:IM-16425-640	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273540.1|refseq:NP_001273541.1|ensembl:ENSP00000258062|ensembl:ENST00000367663|ensembl:ENSP00000356635|ensembl:ENST00000409812|ensembl:ENSP00000386699|ensembl:ENSP00000392065|ensembl:ENST00000258062|refseq:NP_001122089.1|refseq:NP_114128.3|ensembl:ENSG00000135597(gene)|ensembl:ENST00000450536(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814|mint:Q96D71|reactome:R-HSA-8856825|reactome:R-HSA-8856828|genbank_protein_gi:39645197(identity)	refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N|genbank_protein_gi:8885789(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3MDo2J3yQfEm6X0eRAutKvrg+Fo9606	rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606	intact-crc:F767DC2643DAD72A|rigid:CeyNd2llD0upfCZBElJiIblPjEU	false	sufficient binding region:1-743	sufficient binding region:1670-2725	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08AG7	uniprotkb:Q96D71	intact:EBI-2637198|uniprotkb:Q5W0P5|ensembl:ENSP00000367049	intact:EBI-1171195|uniprotkb:Q9BXY9|uniprotkb:Q8NDR7|uniprotkb:Q8WU62|uniprotkb:Q5JWJ7|uniprotkb:Q5JWJ5|uniprotkb:Q5JWJ6|uniprotkb:B7ZBZ8|uniprotkb:B7ZBZ9|uniprotkb:B7ZC00|uniprotkb:J3KP76|intact:EBI-28972584|ensembl:ENSP00000392065	psi-mi:mzt1_human(display_long)|uniprotkb:C13orf37(gene name synonym)|uniprotkb:MOZART1(gene name synonym)|uniprotkb:Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1(gene name synonym)|uniprotkb:MZT1(gene name)|psi-mi:MZT1(display_short)	psi-mi:reps1_human(display_long)|uniprotkb:REPS1(gene name)|psi-mi:REPS1(display_short)|uniprotkb:RalBP1-interacting protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663334|imex:IM-16425-641	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001065243.1|ensembl:ENSG00000204899(gene)|ensembl:ENST00000377818(transcript)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0031021"(interphase microtubule organizing center)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0051415"(microtubule nucleation by interphase microtubule organizing center)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR022214|rcsb pdb:6L81|rcsb pdb:6M33|rcsb pdb:6X0U|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|genbank_protein_gi:115392147(identity)	refseq:NP_001273540.1|refseq:NP_001273541.1|ensembl:ENSP00000258062|ensembl:ENST00000367663|ensembl:ENSP00000356635|ensembl:ENST00000409812|ensembl:ENSP00000386699|ensembl:ENSP00000392065|ensembl:ENST00000258062|refseq:NP_001122089.1|refseq:NP_114128.3|ensembl:ENSG00000135597(gene)|ensembl:ENST00000450536(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814|mint:Q96D71|reactome:R-HSA-8856825|reactome:R-HSA-8856828|genbank_protein_gi:39645197(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:cn9Vdes2T/OFuEERW7DTz3YJ7b09606	rogid:3MDo2J3yQfEm6X0eRAutKvrg+Fo9606	intact-crc:880CE9E480B7CEC6|rigid:3YyGBKRyVBlOx8+hjrvXUHTD9ss	false	sufficient binding region:22-82..82	sufficient binding region:1-743	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15311	uniprotkb:Q96D71	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	intact:EBI-1171195|uniprotkb:Q9BXY9|uniprotkb:Q8NDR7|uniprotkb:Q8WU62|uniprotkb:Q5JWJ7|uniprotkb:Q5JWJ5|uniprotkb:Q5JWJ6|uniprotkb:B7ZBZ8|uniprotkb:B7ZBZ9|uniprotkb:B7ZC00|uniprotkb:J3KP76|intact:EBI-28972584|ensembl:ENSP00000392065	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:reps1_human(display_long)|uniprotkb:REPS1(gene name)|psi-mi:REPS1(display_short)|uniprotkb:RalBP1-interacting protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663351|imex:IM-16425-642	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149|genbank_protein_gi:46358409(identity)	refseq:NP_001273540.1|refseq:NP_001273541.1|ensembl:ENSP00000258062|ensembl:ENST00000367663|ensembl:ENSP00000356635|ensembl:ENST00000409812|ensembl:ENSP00000386699|ensembl:ENSP00000392065|ensembl:ENST00000258062|refseq:NP_001122089.1|refseq:NP_114128.3|ensembl:ENSG00000135597(gene)|ensembl:ENST00000450536(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814|mint:Q96D71|reactome:R-HSA-8856825|reactome:R-HSA-8856828|genbank_protein_gi:39645197(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	rogid:3MDo2J3yQfEm6X0eRAutKvrg+Fo9606	intact-crc:3138F1A2115A67A7|rigid:CrPYtOo8KH4Se5MYIKj9SnYumbs	false	sufficient binding region:460-655	sufficient binding region:1-743	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0DI81	uniprotkb:Q96D71	intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155	intact:EBI-1171195|uniprotkb:Q9BXY9|uniprotkb:Q8NDR7|uniprotkb:Q8WU62|uniprotkb:Q5JWJ7|uniprotkb:Q5JWJ5|uniprotkb:Q5JWJ6|uniprotkb:B7ZBZ8|uniprotkb:B7ZBZ9|uniprotkb:B7ZC00|uniprotkb:J3KP76|intact:EBI-28972584|ensembl:ENSP00000392065	psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short)	psi-mi:reps1_human(display_long)|uniprotkb:REPS1(gene name)|psi-mi:REPS1(display_short)|uniprotkb:RalBP1-interacting protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663368|imex:IM-16425-643	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198|genbank_protein_gi:30851693(identity)	refseq:NP_001273540.1|refseq:NP_001273541.1|ensembl:ENSP00000258062|ensembl:ENST00000367663|ensembl:ENSP00000356635|ensembl:ENST00000409812|ensembl:ENSP00000386699|ensembl:ENSP00000392065|ensembl:ENST00000258062|refseq:NP_001122089.1|refseq:NP_114128.3|ensembl:ENSG00000135597(gene)|ensembl:ENST00000450536(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814|mint:Q96D71|reactome:R-HSA-8856825|reactome:R-HSA-8856828|genbank_protein_gi:39645197(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606	rogid:3MDo2J3yQfEm6X0eRAutKvrg+Fo9606	intact-crc:D3818097A2FB83F5|rigid:ImhyTRNtS/zI627Gdxj6qGJ0qlI	false	sufficient binding region:1-140..140(IPR006722)	sufficient binding region:1-743	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68133	uniprotkb:Q9H6Y7	intact:EBI-367510|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSP00000355645|uniprotkb:Q5T8M9	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	psi-mi:acts_human(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663393|imex:IM-16425-644	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143632(gene)|ensembl:ENST00000366684(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043531"(ADP binding)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68133|reactome:R-HSA-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001091.1|genbank_protein_gi:47078293(identity)	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1|genbank_protein_gi:14149701(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49606	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	intact-crc:98B255FDACD13AE1|rigid:nEdfaUaOsWzFNgU75Nkle56FBVE	false	sufficient binding region:131-377(IPR004000)	sufficient binding region:219-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y4W6	uniprotkb:Q9H6Y7	intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym)	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663411|imex:IM-16425-645	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664|genbank_protein_gi:114672124(identity)	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1|genbank_protein_gi:14149701(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	intact-crc:EB56E9E5FA7FC862|rigid:DD5/UU39WoNdAgiMi48vxk8ElC4	false	sufficient binding region:1-797	sufficient binding region:219-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H6Y7	uniprotkb:O14983	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	intact:EBI-359186|uniprotkb:O14984|uniprotkb:A8K5J9|ensembl:ENSP00000349595|uniprotkb:B3KY17	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:at2a1_human(display_long)|uniprotkb:ATP2A1(gene name)|psi-mi:ATP2A1(display_short)|uniprotkb:Calcium pump 1(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663428|imex:IM-16425-646	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1|genbank_protein_gi:14149701(identity)	refseq:NP_004311.1|refseq:NP_775293.1|ensembl:ENSG00000196296(gene)|ensembl:ENST00000357084(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0031673"(H zone)|go:"GO:0031674"(I band)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034704"(calcium channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:0106134"(positive regulation of cardiac muscle cell contraction)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902082"(positive regulation of calcium ion import into sarcoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O14983|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001273004.1|genbank_protein_gi:47132613(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	rogid:3cHH/E8HuaFCoTd7hO/0SFTnqtg9606	intact-crc:D23B8B16B4547857|rigid:s3nYIBNXXNMDqZYvvdrPbddm4xg	false	sufficient binding region:219-350	sufficient binding region:817-1001..1001	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12883	uniprotkb:Q9H6Y7	intact:EBI-519141|uniprotkb:Q14836|uniprotkb:Q14837|uniprotkb:Q14904|uniprotkb:Q16579|uniprotkb:Q2M1Y6|uniprotkb:Q92679|uniprotkb:Q9H1D5|ensembl:ENSP00000347507|uniprotkb:Q9UMM8|uniprotkb:A2TDB6|uniprotkb:B6D424|uniprotkb:Q9UDA2	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	psi-mi:myh7_human(display_long)|uniprotkb:Myosin heavy chain 7(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle beta isoform(gene name synonym)|uniprotkb:Myosin heavy chain slow isoform(gene name synonym)|uniprotkb:MYH7(gene name)|psi-mi:MYH7(display_short)|uniprotkb:MYHCB(gene name synonym)	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663445|imex:IM-16425-647	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092054(gene)|ensembl:ENST00000355349(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031449"(regulation of slow-twitch skeletal muscle fiber contraction)|go:"GO:0032982"(myosin filament)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P12883|rcsb pdb:1IK2|rcsb pdb:2FXM|rcsb pdb:2FXO|rcsb pdb:3DTP|rcsb pdb:4DB1|rcsb pdb:4P7H|rcsb pdb:4PA0|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA4|rcsb pdb:4XA6|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ1|rcsb pdb:5CJ4|rcsb pdb:5TBY|rcsb pdb:5WJ7|rcsb pdb:5WJB|rcsb pdb:5WLQ|rcsb pdb:5WLZ|rcsb pdb:5WME|rcsb pdb:6PF2|rcsb pdb:6PFP|refseq:NP_000248.2|refseq:XP_016876829.1|genbank_protein_gi:115496168(identity)	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1|genbank_protein_gi:14149701(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Fz6cO12gihAyDMe06hLrQbrupbs9606	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	intact-crc:3E4292AC9FE826F3|rigid:2hLjpPUG0Pjs+AmX1zejcFlLyJM	false	sufficient binding region:305-1935	sufficient binding region:219-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H6Y7	uniprotkb:P63165	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663462|imex:IM-16425-648	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1|genbank_protein_gi:14149701(identity)	refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N|genbank_protein_gi:54792066(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606	intact-crc:2970712CF3250E9B|rigid:1sWOY/sTD7CYO80VQnXo5UwlPJE	false	sufficient binding region:219-350	sufficient binding region:49-101	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H6Y7	uniprotkb:Q8WZ42	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663479|imex:IM-16425-649	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1|genbank_protein_gi:14149701(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:064C32BE94484099|rigid:oKf4MP7SzvrR2c5jUc5ywIjucjk	false	sufficient binding region:219-350	sufficient binding region:31332-34350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H6Y7	uniprotkb:P51965	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663496|imex:IM-16425-650	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1|genbank_protein_gi:14149701(identity)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1|genbank_protein_gi:33359692(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:4FB0378BC5055E63|rigid:QB1hgffvKC0vzUWZSinyWzDtvoQ	false	sufficient binding region:219-350	sufficient binding region:1-193	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H6Y7	uniprotkb:Q969T4	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663513|imex:IM-16425-651	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1|genbank_protein_gi:14149701(identity)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1|genbank_protein_gi:33359693(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:BB99AD101581278C|rigid:qwIoWeYLwqpGjcONYIf/eML/nkM	false	sufficient binding region:219-350	sufficient binding region:1-207(IPR000608)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55042	uniprotkb:Q6ZP82	intact:EBI-3911502|uniprotkb:Q96F39|ensembl:ENSP00000299759|ensembl:ENSP00000388744	intact:EBI-928795|uniprotkb:Q8N8H3|uniprotkb:H7C0P1|uniprotkb:J3KNW6	psi-mi:rad_human(display_long)|uniprotkb:RRAD(gene name)|psi-mi:RRAD(display_short)|uniprotkb:RAD(gene name synonym)|uniprotkb:RAD1(gene name synonym)|uniprotkb:Ras associated with diabetes(gene name synonym)	psi-mi:cc141_human(display_long)|uniprotkb:CCDC141(gene name)|psi-mi:CCDC141(display_short)|uniprotkb:Coiled-coil protein associated with myosin II and DISC1(gene name synonym)|uniprotkb:CAMDI(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663531|imex:IM-16425-652	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001122322.1|refseq:NP_004156.1|ensembl:ENSG00000166592(gene)|ensembl:ENST00000299759(transcript)|ensembl:ENST00000420652(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|interpro:IPR028869|rcsb pdb:2DPX|rcsb pdb:2GJS|rcsb pdb:3Q72|rcsb pdb:3Q7P|rcsb pdb:3Q7Q|reactome:R-HSA-9031628|ensembl:ENSP00000299759|ensembl:ENSP00000388744|genbank_protein_gi:4759053(identity)	ensembl:ENST00000443758|ensembl:ENSP00000390190|ensembl:ENSG00000163492|refseq:NP_775919.3|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0043005"(neuron projection)|go:"GO:0051642"(centrosome localization)|genbank_protein_gi:39725716(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/12/09	rogid:YqjKdnFhNGqAtV4zoGvflucSYws9606	rogid:WKgnBWIkZsyOYma0rbtbY4zCwZg9606	intact-crc:6FA0442200C5EC3B|rigid:dQ4FBkUX9XMfrVXXfYOp+5GhAyo	false	sufficient binding region:1-308	sufficient binding region:786-1450	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16586	uniprotkb:P02751-1	intact:EBI-5663553|uniprotkb:A8K3K7|uniprotkb:A6NEB8|uniprotkb:Q13710|uniprotkb:Q13712|ensembl:ENSP00000262018	intact:EBI-22099195|ensembl:ENSP00000352696	psi-mi:sgca_human(display_long)|uniprotkb:50 kDa dystrophin-associated glycoprotein(gene name synonym)|uniprotkb:ADL(gene name synonym)|uniprotkb:Adhalin(gene name synonym)|uniprotkb:DAG2(gene name synonym)|uniprotkb:Dystroglycan-2(gene name synonym)|uniprotkb:SGCA(gene name)|psi-mi:SGCA(display_short)	psi-mi:p02751-1(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:Cold-insoluble globulin(gene name synonym)|uniprotkb:FN(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663548|imex:IM-16425-653	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000014.1|refseq:NP_001129169.1|ensembl:ENSG00000108823(gene)|ensembl:ENST00000262018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045121"(membrane raft)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008908(Sarcoglycan alphaepsilon)|interpro:IPR015919(Cadherin-like)|interpro:IPR028658|genbank_protein_gi:19344018(identity)	intact:EBI-1220319(isoform-parent)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000359671(transcript)|genbank_protein_gi:47132548(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2019/10/18	rogid:Qwp5JSgrzjgSv2aXNPootfebHSg9606	rogid:mrg1VDkvoOn5kbtGtkLOeYhRHqE9606	intact-crc:F189A73A562C3EA4|rigid:2+yMFCsxVoIik2cLDpoq3RyOYao	false	sufficient binding region:313-387	sufficient binding region:75-2386(IPR000083)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12841	uniprotkb:Q16586	intact:EBI-2349801|uniprotkb:Q549Z0|uniprotkb:A8K523|uniprotkb:B4DTT5|uniprotkb:D3DN90|ensembl:ENSP00000295633	intact:EBI-5663553|uniprotkb:A8K3K7|uniprotkb:A6NEB8|uniprotkb:Q13710|uniprotkb:Q13712|ensembl:ENSP00000262018	psi-mi:fstl1_human(display_long)|uniprotkb:FSTL1(gene name)|psi-mi:FSTL1(display_short)|uniprotkb:FRP(gene name synonym)|uniprotkb:Follistatin-like protein 1(gene name synonym)	psi-mi:sgca_human(display_long)|uniprotkb:50 kDa dystrophin-associated glycoprotein(gene name synonym)|uniprotkb:ADL(gene name synonym)|uniprotkb:Adhalin(gene name synonym)|uniprotkb:DAG2(gene name synonym)|uniprotkb:Dystroglycan-2(gene name synonym)|uniprotkb:SGCA(gene name)|psi-mi:SGCA(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663574|imex:IM-16425-654	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009016.1|ensembl:ENSG00000163430(gene)|ensembl:ENST00000295633(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0008201"(heparin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR036058|reactome:R-HSA-201451|reactome:R-HSA-381426|reactome:R-HSA-8957275|genbank_protein_gi:33990756(identity)	refseq:NP_000014.1|refseq:NP_001129169.1|ensembl:ENSG00000108823(gene)|ensembl:ENST00000262018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045121"(membrane raft)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008908(Sarcoglycan alphaepsilon)|interpro:IPR015919(Cadherin-like)|interpro:IPR028658|genbank_protein_gi:19344018(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2Y10WyTpml76Ksjw+X7dXUozFg09606	rogid:Qwp5JSgrzjgSv2aXNPootfebHSg9606	intact-crc:21C982C68EC79BDB|rigid:M9Hqfu4vhTfAt7cDTWtB60abwuA	false	sufficient binding region:252-308	sufficient binding region:313-387	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKP3	uniprotkb:Q16586	intact:EBI-5659717|uniprotkb:Q32N04|ensembl:ENSP00000362935|uniprotkb:Q549J7	intact:EBI-5663553|uniprotkb:A8K3K7|uniprotkb:A6NEB8|uniprotkb:Q13710|uniprotkb:Q13712|ensembl:ENSP00000262018	psi-mi:itbp2_human(display_long)|uniprotkb:Melusin(gene name synonym)|uniprotkb:MSTP015(orf name)|uniprotkb:ITGB1BP2(gene name)|psi-mi:ITGB1BP2(display_short)	psi-mi:sgca_human(display_long)|uniprotkb:50 kDa dystrophin-associated glycoprotein(gene name synonym)|uniprotkb:ADL(gene name synonym)|uniprotkb:Adhalin(gene name synonym)|uniprotkb:DAG2(gene name synonym)|uniprotkb:Dystroglycan-2(gene name synonym)|uniprotkb:SGCA(gene name)|psi-mi:SGCA(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663591|imex:IM-16425-655	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147166(gene)|ensembl:ENST00000373829(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030018"(Z disc)|interpro:IPR007051(CHORD)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|interpro:IPR007052(CS domain)|refseq:NP_036410.1|genbank_protein_gi:6912437(identity)	refseq:NP_000014.1|refseq:NP_001129169.1|ensembl:ENSG00000108823(gene)|ensembl:ENST00000262018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045121"(membrane raft)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008908(Sarcoglycan alphaepsilon)|interpro:IPR015919(Cadherin-like)|interpro:IPR028658|genbank_protein_gi:19344018(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ATXkBI3+UoEgYYVG97Eab5OtGZE9606	rogid:Qwp5JSgrzjgSv2aXNPootfebHSg9606	intact-crc:8F927FE3894A4FEA|rigid:GrvtHhrjr2+a3Kn8t2V536wOt7I	false	sufficient binding region:170-347..347(IPR007052)	sufficient binding region:313-387	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16586	uniprotkb:P21675	intact:EBI-5663553|uniprotkb:A8K3K7|uniprotkb:A6NEB8|uniprotkb:Q13710|uniprotkb:Q13712|ensembl:ENSP00000262018	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	psi-mi:sgca_human(display_long)|uniprotkb:50 kDa dystrophin-associated glycoprotein(gene name synonym)|uniprotkb:ADL(gene name synonym)|uniprotkb:Adhalin(gene name synonym)|uniprotkb:DAG2(gene name synonym)|uniprotkb:Dystroglycan-2(gene name synonym)|uniprotkb:SGCA(gene name)|psi-mi:SGCA(display_short)	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663610|imex:IM-16425-656	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000014.1|refseq:NP_001129169.1|ensembl:ENSG00000108823(gene)|ensembl:ENST00000262018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045121"(membrane raft)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008908(Sarcoglycan alphaepsilon)|interpro:IPR015919(Cadherin-like)|interpro:IPR028658|genbank_protein_gi:19344018(identity)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N|genbank_protein_gi:20357587(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Qwp5JSgrzjgSv2aXNPootfebHSg9606	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	intact-crc:06996D31139FE13E|rigid:rQ1qIdzwG73MIXcgvMMI8c48Vto	false	sufficient binding region:313-387	sufficient binding region:1047-1872	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969Q1	uniprotkb:Q16585	intact:EBI-5661333|uniprotkb:Q9BYV4|uniprotkb:Q96BD3|uniprotkb:Q96KD9|uniprotkb:Q5T2I1|uniprotkb:B4DN95|ensembl:ENSP00000363390	intact:EBI-5663627|uniprotkb:B7Z635|uniprotkb:O00661|ensembl:ENSP00000370839	psi-mi:tri63_human(display_long)|uniprotkb:IRF(gene name synonym)|uniprotkb:Iris RING finger protein(gene name synonym)|uniprotkb:MURF1(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 28(gene name synonym)|uniprotkb:RNF28(gene name synonym)|uniprotkb:SMRZ(gene name synonym)|uniprotkb:Striated muscle RING zinc finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 63(gene name synonym)|uniprotkb:TRIM63(gene name)|psi-mi:TRIM63(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM63(gene name synonym)	psi-mi:sgcb_human(display_long)|uniprotkb:43 kDa dystrophin-associated glycoprotein(gene name synonym)|uniprotkb:A3b(gene name synonym)|uniprotkb:SGCB(gene name)|psi-mi:SGCB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663632|imex:IM-16425-657	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115977.2|ensembl:ENSG00000158022(gene)|ensembl:ENST00000374272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR042667|mint:Q969Q1|rcsb pdb:2D8U|rcsb pdb:3DDT|rcsb pdb:4M3L|reactome:R-HSA-9615017|reactome:R-HSA-983168|genbank_protein_gi:19924162(identity)	refseq:NP_000223.1|ensembl:ENSG00000163069(gene)|ensembl:ENST00000381431(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0097084"(vascular associated smooth muscle cell development)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027659|mint:Q16585|genbank_protein_gi:1794188(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:fxaNyoTJdzJyjJb+QYEZ+d72DbA9606	rogid:3kGYgS5HdH4e/aCHMtAnVJQDYjI9606	intact-crc:BBEC44E6C1875FBC|rigid:M58dINQrEa1FEDAzx1wY0YrXjDE	false	sufficient binding region:217-353	sufficient binding region:10-65	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01011	uniprotkb:Q92629	intact:EBI-296557|uniprotkb:Q9UC47|uniprotkb:Q13703|uniprotkb:Q2TU87|uniprotkb:Q2TU88|uniprotkb:Q59GP9|uniprotkb:Q6LBY8|uniprotkb:Q6LDT7|uniprotkb:Q6NSC9|uniprotkb:Q8N177|uniprotkb:Q96DW8|uniprotkb:Q9UNU9|uniprotkb:B3KVQ7|ensembl:ENSP00000376793|ensembl:ENSP00000376795|ensembl:ENSP00000450540	intact:EBI-3904504|uniprotkb:Q99644|uniprotkb:A8K9S9|uniprotkb:Q53XA5|ensembl:ENSP00000403003	psi-mi:aact_human(display_long)|uniprotkb:Cell growth-inhibiting gene 24/25 protein(gene name synonym)|uniprotkb:SERPINA3(gene name)|psi-mi:SERPINA3(display_short)|uniprotkb:AACT(gene name synonym)|uniprotkb:GIG24(orf name)|uniprotkb:GIG25(orf name)|uniprotkb:Serpin A3(gene name synonym)	psi-mi:sgcd_human(display_long)|uniprotkb:SGCD(gene name)|psi-mi:SGCD(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663649|imex:IM-16425-658	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006953"(acute-phase response)|refseq:NP_001076.2|ensembl:ENSG00000196136(gene)|ensembl:ENST00000393078(transcript)|ensembl:ENST00000393080(transcript)|ensembl:ENST00000467132(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|reactome:R-HSA-6798695|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0006954"(inflammatory response)|interpro:IPR023795|interpro:IPR023796|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01011|rcsb pdb:1AS4|rcsb pdb:1QMN|rcsb pdb:2ACH|rcsb pdb:3CAA|rcsb pdb:3DLW|rcsb pdb:4CAA|rcsb pdb:6HGE|reactome:R-HSA-114608|genbank_protein_gi:13097704(identity)	refseq:XP_011532923.1|refseq:NP_000328.2|refseq:NP_001121681.1|refseq:NP_758447.1|refseq:XP_005266023.1|refseq:XP_016865212.1|refseq:XP_016865213.1|ensembl:ENSG00000170624(gene)|ensembl:ENST00000435422(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027661|interpro:IPR039972|genbank_protein_gi:1495426(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LTdrRsWwtOm8QvOWZ4h0SO8EuP09606	rogid:RM2mAw5eLS+XWJwBV5oTaYNZTLo9606	intact-crc:0B233E2BC7D303DA|rigid:6iTWh6Ok9E9DgTYf81qF/59YsBE	false	sufficient binding region:369-423..423(IPR000215)	sufficient binding region:1-36	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:P21399	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-2847111|uniprotkb:Q5VZA7|uniprotkb:Q14652|uniprotkb:D3DRK7|ensembl:ENSP00000309477|ensembl:ENSP00000369255|ensembl:ENSP00000438733	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:acohc_human(display_long)|uniprotkb:ACO1(gene name)|psi-mi:ACO1(display_short)|uniprotkb:IREB1(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Ferritin repressor protein(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663667|imex:IM-16425-659	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	refseq:XP_011516190.1|refseq:NP_001265281.1|refseq:NP_002188.1|refseq:XP_005251533.1|ensembl:ENSG00000122729(gene)|ensembl:ENST00000309951(transcript)|ensembl:ENST00000379923(transcript)|ensembl:ENST00000541043(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR029784|interpro:IPR036008|interpro:IPR044137|mint:P21399|rcsb pdb:2B3X|rcsb pdb:2B3Y|reactome:R-HSA-917937|go:"GO:0009791"(post-embryonic development)|genbank_protein_gi:17390224(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:hcZPPf3fTfqol8El1L5kwVEljyY9606	intact-crc:9915B296B693D66D|rigid:LVF/mRXprKOabQWnqHbTYIchFaE	false	sufficient binding region:1-36	sufficient binding region:347-889	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:P40227	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663684|imex:IM-16425-660	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|genbank_protein_gi:76827910(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:7CE38B37C906B1B9|rigid:Et2SeHPnWecSdxbvfJnJthAsZjs	false	sufficient binding region:1-36	sufficient binding region:66-531(IPR002423)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:O75190	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663703|imex:IM-16425-661	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|genbank_protein_gi:34328906(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	intact-crc:D9F7A10A59DDC616|rigid:NKAqXZfmYgfpJEF6LIV3aRchIdU	false	sufficient binding region:1-36	sufficient binding region:102-326	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q13326	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663720|imex:IM-16425-662	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	intact-crc:1465F58EFF57005D|rigid:5x0J6GQ8QRgGGVUDOclpkDRd0OQ	false	sufficient binding region:1559-2080(IPR000008)	sufficient binding region:1-36	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75923	uniprotkb:Q13326	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|uniprotkb:A0FK00|ensembl:ENSP00000258104	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663738|imex:IM-16425-663	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|ensembl:ENST00000258104(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042383"(sarcolemma)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|ensembl:ENSG00000135636(gene)|genbank_protein_gi:19743938(identity)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	intact-crc:A7967C7A8B57313C|rigid:5x0J6GQ8QRgGGVUDOclpkDRd0OQ	false	sufficient binding region:1162-2080(IPR000008)	sufficient binding region:1-36	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:P06733	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663756|imex:IM-16425-664	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:41655BB1906ACF40|rigid:BTGPDePqjqaPoOympiOiFtm54Ic	false	sufficient binding region:1-36	sufficient binding region:126-434(IPR000941)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:P13929	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663774|imex:IM-16425-665	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:33878987(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:6BA8C97259192604|rigid:tDE7OBLAnQBgkhePAIJ4J6zE7LY	false	sufficient binding region:1-36	sufficient binding region:126-434(IPR000941)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08107	uniprotkb:Q13326	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663792|imex:IM-16425-666	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|genbank_protein_gi:39645781(identity)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	intact-crc:45E67410587E481C|rigid:zkpIbszu3z0YSsB+fj61iQ4X0b4	false	sufficient binding region:75-641(IPR001023)	sufficient binding region:1-36	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:Q00872	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663810|imex:IM-16425-667	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:C8D8AC668D66B4C7|rigid:X+kOsHKtPaZENvsNLNHNj0rB55Q	false	sufficient binding region:1-36	sufficient binding region:698-1141(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:Q13326	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663828|imex:IM-16425-668	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	intact-crc:32D5A99782FF6B2D|rigid:HMZDOfx6pzTBsvMSXtFu3oYtC48	false	sufficient binding region:469-1141(IPR007110)	sufficient binding region:1-36	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:Q14324	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663846|imex:IM-16425-669	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:F638F41DCF7DB025|rigid:HMZDOfx6pzTBsvMSXtFu3oYtC48	false	sufficient binding region:1-36	sufficient binding region:415-1141(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:Q96A32	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-1390771|uniprotkb:Q14843|uniprotkb:Q6IB41|uniprotkb:B2RA83|ensembl:ENSP00000325239	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:mlrs_human(display_long)|uniprotkb:Fast skeletal myosin light chain 2(gene name synonym)|uniprotkb:MLC2B(gene name synonym)|uniprotkb:MYLPF(gene name)|psi-mi:MYLPF(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663864|imex:IM-16425-670	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	refseq:NP_037424.2|refseq:NP_001311387.1|refseq:NP_001311388.1|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006955"(immune response)|go:"GO:0007519"(skeletal muscle tissue development)|ensembl:ENSG00000180209(gene)|ensembl:ENST00000322861(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008307"(structural constituent of muscle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|reactome:R-HSA-445355|genbank_protein_gi:28372498(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:b6CSTg+Cx0VNPQ+V3X2Q7ibzAcE9606	intact-crc:6FC6E3FF862FC75B|rigid:wKiGo2cmlMktivhhkXCCFdTVO14	false	sufficient binding region:1-36	sufficient binding region:1-169(IPR002048)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:P07602	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-716699|uniprotkb:Q53Y86|uniprotkb:P07292|uniprotkb:P15793|uniprotkb:P78538|uniprotkb:P78541|uniprotkb:P78546|uniprotkb:P78547|uniprotkb:P78558|uniprotkb:Q6IBQ6|uniprotkb:Q92739|uniprotkb:Q92740|uniprotkb:Q92741|uniprotkb:Q92742|ensembl:ENSP00000378394	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:sap_human(display_long)|uniprotkb:PSAP(gene name)|psi-mi:PSAP(display_short)|uniprotkb:GLBA(gene name synonym)|uniprotkb:SAP1(gene name synonym)|uniprotkb:Proactivator polypeptide(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663882|imex:IM-16425-671	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	refseq:NP_001035930.1|refseq:NP_001035931.1|refseq:NP_002769.1|ensembl:ENSG00000197746(gene)|ensembl:ENST00000394936(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0007041"(lysosomal transport)|go:"GO:1905576"(ganglioside GT1b binding)|go:"GO:1905577"(ganglioside GP1c binding)|interpro:IPR003119(Saposin type A)|interpro:IPR007856(Saposin-like type B, 1)|interpro:IPR008138(Saposin-like type B, 2)|interpro:IPR008139(Saposin B)|interpro:IPR008373(Saposin)|interpro:IPR011001(Saposin-like)|interpro:IPR021165|rcsb pdb:1M12|rcsb pdb:1N69|rcsb pdb:1SN6|rcsb pdb:2DOB|rcsb pdb:2GTG|rcsb pdb:2QYP|rcsb pdb:2R0R|rcsb pdb:2R1Q|rcsb pdb:2RB3|rcsb pdb:2Z9A|rcsb pdb:3BQP|rcsb pdb:3BQQ|rcsb pdb:4DDJ|rcsb pdb:4UEX|rcsb pdb:4V2O|rcsb pdb:6SLR|reactome:R-HSA-114608|go:"GO:1905575"(ganglioside GM3 binding)|reactome:R-HSA-1660662|reactome:R-HSA-418594|reactome:R-HSA-6798695|reactome:R-HSA-375276|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1903771"(positive regulation of beta-galactosidase activity)|go:"GO:1905572"(ganglioside GM1 transport to membrane)|go:"GO:1905573"(ganglioside GM1 binding)|go:"GO:1905574"(ganglioside GM2 binding)|dip:DIP-29803N|genbank_protein_gi:110224477(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:DV9GeJ6/mtgv9nUhsCRYBo19d5g9606	intact-crc:6D125B930903DA0C|rigid:T517XfOISneaoVibYK1IpsisjOg	false	sufficient binding region:1-36	sufficient binding region:441-524..524(IPR003119)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:P11217	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663901|imex:IM-16425-672	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	intact-crc:0C2AF904FFA102D0|rigid:XSH1gAZL5EzhZt1LbgjCIwFjdQY	false	sufficient binding region:1-36	sufficient binding region:160-842	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13326	uniprotkb:Q96I99	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	intact:EBI-2511878|ensembl:ENSP00000307432|uniprotkb:Q8WUQ1|uniprotkb:Q86VX8|uniprotkb:O95195|uniprotkb:Q6NUH7|uniprotkb:C9JVT2	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:sucb2_human(display_long)|uniprotkb:SUCLG2(gene name)|psi-mi:SUCLG2(display_short)|uniprotkb:GTP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-G chain(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663918|imex:IM-16425-673	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	ensembl:ENSG00000172340(gene)|ensembl:ENST00000307227(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034722|mint:Q96I99|rcsb pdb:6WCV|reactome:R-HSA-71403|refseq:NP_001171070.1|refseq:NP_003839.2|dip:DIP-53563N|genbank_protein_gi:29788999(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	rogid:jxrFGuu3hFn2QAYfrPxTKhScM249606	intact-crc:599F3F5D0101D5B3|rigid:2pvq7KFms2aW0n+O3TDjZeE3dAI	false	sufficient binding region:1-36	sufficient binding region:114-432(IPR005809)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q13326	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663936|imex:IM-16425-674	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	intact-crc:9572B57999442F17|rigid:2BK4VZZl4H1Z9USzWFP4hNnDBzI	false	sufficient binding region:27509-34350(IPR003599)	sufficient binding region:1-36	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q13326	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5357343|uniprotkb:Q32M32|uniprotkb:Q5T9J6|ensembl:ENSP00000218867	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:sgcg_human(display_long)|uniprotkb:SGCG(gene name)|psi-mi:SGCG(display_short)|uniprotkb:35 kDa dystrophin-associated glycoprotein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663955|imex:IM-16425-675	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349720(identity)	refseq:NP_000222.1|refseq:XP_005266562.1|ensembl:ENSG00000102683(gene)|ensembl:ENST00000218867(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027660|interpro:IPR039972|genbank_protein_gi:1054902(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:bjOu3nIcmlNvr9KesPmbMEZ7sHU9606	intact-crc:2752B8AD1B7B2EF1|rigid:2BK4VZZl4H1Z9USzWFP4hNnDBzI	false	sufficient binding region:5265-34350(IPR003599)	sufficient binding region:1-36	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23610	uniprotkb:Q9Y371	intact:EBI-5663973|uniprotkb:Q8IXP3|uniprotkb:Q5HY66|intact:EBI-28971382|ensembl:ENSP00000358518|ensembl:ENSP00000477530|ensembl:ENSP00000479624	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	psi-mi:hap40_human(display_long)|uniprotkb:CpG island protein(gene name synonym)|uniprotkb:F8A1(gene name)|psi-mi:F8A1(display_short)|uniprotkb:F8A2(gene name)|psi-mi:F8A2(display_short)|uniprotkb:F8A3(gene name)|psi-mi:F8A3(display_short)|uniprotkb:Factor VIII intron 22 protein(gene name synonym)	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663981|imex:IM-16425-676	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000358518|ensembl:ENSP00000479624|ensembl:ENSP00000477530|refseq:NP_001007524.1|refseq:NP_001007525.1|refseq:NP_036283.2|ensembl:ENSG00000277150(gene)|ensembl:ENSG00000288709(gene)|ensembl:ENSG00000288722(gene)|ensembl:ENST00000369505(transcript)|ensembl:ENST00000610495(transcript)|ensembl:ENST00000622749(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0016604"(nuclear body)|go:"GO:0099518"(vesicle cytoskeletal trafficking)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR039494|rcsb pdb:6EZ8|rcsb pdb:6X9O|rcsb pdb:7DXJ|rcsb pdb:7DXK|genbank_protein_gi:56790933(identity)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:34782815(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:btVfuF/KKUSWmbRdXS4b4Vdi3wE9606	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	intact-crc:7F98F30A91AD5FE6|rigid:6+q2q/aHqTmIokdL0L8LJtBxGW4	false	sufficient binding region:299-371..371	sufficient binding region:68-365	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y371	uniprotkb:P02751	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5663998|imex:IM-16425-677	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:34782815(identity)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|genbank_protein_gi:47132548(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2019/10/18	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:F890B6607D8E7633|rigid:l0gWlGzMAfSvS1OPD4VROSLVWLk	false	sufficient binding region:68-365	sufficient binding region:1760-2477(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y371	uniprotkb:P09211	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607|uniprotkb:Q5TZY3	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664016|imex:IM-16425-678	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:34782815(identity)	refseq:NP_000843.1|ensembl:ENSG00000084207(gene)|go:"GO:0000302"(response to reactive oxygen species)|ensembl:ENST00000398606(transcript)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009890"(negative regulation of biosynthetic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0035732"(nitric oxide storage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7GSS|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|genbank_protein_gi:6552334(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606	intact-crc:0D55D517BD464306|rigid:jEhuiP8gVS1CDvzzpeqt/I7K2Ck	false	sufficient binding region:68-365	sufficient binding region:1-210(IPR003082)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y371	uniprotkb:P53611	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	intact:EBI-536715|uniprotkb:Q92697|ensembl:ENSP00000317473	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:pgtb2_human(display_long)|uniprotkb:Geranylgeranyl transferase type II subunit beta(gene name synonym)|uniprotkb:Type II protein geranyl-geranyltransferase subunit beta(gene name synonym)|uniprotkb:Rab geranylgeranyltransferase subunit beta(gene name synonym)|uniprotkb:Rab geranyl-geranyltransferase subunit beta(gene name synonym)|uniprotkb:GGTB(gene name synonym)|uniprotkb:RABGGTB(gene name)|psi-mi:RABGGTB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664034|imex:IM-16425-679	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:34782815(identity)	ensembl:ENSG00000137955(gene)|ensembl:ENST00000319942(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026873|rcsb pdb:6J6X|rcsb pdb:6J74|rcsb pdb:6J7F|rcsb pdb:6J7X|rcsb pdb:6O60|reactome:R-HSA-6803205|reactome:R-HSA-8873719|refseq:NP_004573.2|genbank_protein_gi:21359853(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rogid:M3Np3wsIU/vmKzTNoVg44tPghtw9606	intact-crc:58970E3F1A0A02A0|rigid:GqX/vWpqrVoHBMMRlRxqHmXYLFE	false	sufficient binding region:68-365	sufficient binding region:14-331(IPR001330)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y371	uniprotkb:Q9Y371	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664052|imex:IM-16425-680	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:34782815(identity)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:14727126(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	intact-crc:382644843187256C|rigid:uz0aexElGikh1OIE4nQpOv4aZ0w	false	sufficient binding region:68-365	sufficient binding region:49-365(IPR004148)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NR46	uniprotkb:Q9Y371	intact:EBI-749607|uniprotkb:A8MPS4|uniprotkb:Q8WY61|uniprotkb:Q96JH9|uniprotkb:A6NC47|ensembl:ENSP00000361640|ensembl:ENSP00000361645	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	psi-mi:shlb2_human(display_long)|uniprotkb:SH3 domain-containing GRB2-like protein B2(gene name synonym)|uniprotkb:SH3GLB2(gene name)|psi-mi:SH3GLB2(display_short)|uniprotkb:KIAA1848(gene name synonym)|uniprotkb:PP578(orf name)	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664070|imex:IM-16425-681	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064530.1|refseq:NP_001273974.1|refseq:NP_001273975.1|refseq:XP_005252158.1|ensembl:ENSG00000148341(gene)|ensembl:ENST00000372559(transcript)|ensembl:ENST00000372564(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035640|interpro:IPR036028|mint:Q9NR46|genbank_protein_gi:24431995(identity)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:34782815(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9C0QF9xLb5A6eYQBK2aU/J1aGVo9606	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	intact-crc:D909E073A85AE446|rigid:MqTvL3cr+G8PmP0AxAeARhEqIv4	false	sufficient binding region:163-395(IPR004148)	sufficient binding region:68-365	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y371	uniprotkb:Q86VP1	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	intact:EBI-529518|uniprotkb:O60398|uniprotkb:O95770|uniprotkb:Q13311|uniprotkb:Q9BQG5|uniprotkb:Q9UI88|uniprotkb:B4DKU7|uniprotkb:E7ENV2|uniprotkb:A4D196|ensembl:ENSP00000379612	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:taxb1_human(display_long)|uniprotkb:TRAF6-binding protein(gene name synonym)|uniprotkb:TAX1BP1(gene name)|psi-mi:TAX1BP1(display_short)|uniprotkb:T6BP(gene name synonym)|uniprotkb:PRO0105(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664088|imex:IM-16425-682	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:34782815(identity)	refseq:NP_001073333.1|refseq:NP_001193830.1|refseq:NP_001193831.1|refseq:NP_006015.4|dip:DIP-33010N|ensembl:ENSG00000106052(gene)|ensembl:ENST00000396319(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0019900"(kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q86VP1|rcsb pdb:2M7Q|rcsb pdb:4BMJ|rcsb pdb:4NLH|rcsb pdb:4Z4K|rcsb pdb:4Z4M|rcsb pdb:5AAS|rcsb pdb:5YT6|rcsb pdb:5Z7G|reactome:R-HSA-5357905|reactome:R-HSA-936440|genbank_protein_gi:34193359(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rogid:OJfD9nSzpjJ3bMbHugSDVJ9fj/E9606	intact-crc:569C35F453B52DEB|rigid:TQ5hSMl04OMHtcQQzVQBsq48XGs	false	sufficient binding region:68-365	sufficient binding region:386-789	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y371	uniprotkb:Q8WZ42	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664105|imex:IM-16425-683	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:34782815(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:4B183C9C2D7DE753|rigid:dUlExqkluPuRYI3Ktfya6m5GaaM	false	sufficient binding region:68-365	sufficient binding region:31485-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96S82	uniprotkb:Q9Y371	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664123|imex:IM-16425-684	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1|genbank_protein_gi:41152105(identity)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|genbank_protein_gi:34782815(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	intact-crc:56B35590A725E838|rigid:Qa46bgFYn0I30aFUTpUajyDbPic	false	sufficient binding region:105-380	sufficient binding region:68-365	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:P35609	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664140|imex:IM-16425-685	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	intact-crc:4B68135A8989654C|rigid:BPfJCUUy+bmfTO0w1iVD1kTCbZQ	false	sufficient binding region:34-136	sufficient binding region:356-894	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:P05023	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664157|imex:IM-16425-686	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|genbank_protein_gi:48762680(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:417389C73B38F030|rigid:kUno18bV3+DZqfFL+JYsUM3MbTk	false	sufficient binding region:34-136	sufficient binding region:570-1023(IPR001757)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00499	uniprotkb:O95295	intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664176|imex:IM-16425-687	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N|genbank_protein_gi:4757748(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:BDDD3CC6ADA14904|rigid:IW2IvcQJXivUuX5dQNc3eKMlE/c	false	sufficient binding region:9-593	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q6QNY1	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664193|imex:IM-16425-688	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1|genbank_protein_gi:46852397(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606	intact-crc:8393D80C89DD71D0|rigid:zRrgXWfdv83HfX7fHBuv6uw1ucA	false	sufficient binding region:34-136	sufficient binding region:86-142..142	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q5VT25	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664210|imex:IM-16425-689	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1|genbank_protein_gi:30089959(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:5FA54B8B5C551B94|rigid:W5Is7zcmqZviT7OCsBlg9ftlUvI	false	sufficient binding region:34-136	sufficient binding region:662-1732	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q5SW79	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664227|imex:IM-16425-690	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N|genbank_protein_gi:109255229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606	intact-crc:B939089F489BB01F|rigid:6qQsCs7UcOHx2Z/GqEW21YkJt1Y	false	sufficient binding region:34-136	sufficient binding region:1062-1584	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3K9	uniprotkb:O95295	intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664244|imex:IM-16425-691	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9|genbank_protein_gi:62241002(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:FB123ED51B940589|rigid:8LPKLY2IJRMzS0d8p+ymMiEEKXc	false	sufficient binding region:3532-4069	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17661	uniprotkb:O95295	intact:EBI-1055572|uniprotkb:Q15787|uniprotkb:Q8IZR1|uniprotkb:Q8IZR6|uniprotkb:Q8NES2|uniprotkb:Q8NEU6|uniprotkb:Q8TAC4|uniprotkb:Q8TCX2|uniprotkb:Q8TD99|uniprotkb:Q9UHN5|uniprotkb:Q9UJ80|uniprotkb:Q549R7|uniprotkb:Q549R8|uniprotkb:Q549R9|ensembl:ENSP00000363071	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:desm_human(display_long)|uniprotkb:DES(gene name)|psi-mi:DES(display_short)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664261|imex:IM-16425-692	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001918.3|ensembl:ENSG00000175084(gene)|ensembl:ENST00000373960(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005916"(fascia adherens)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|mint:P17661|reactome:R-HSA-390522|genbank_protein_gi:55749931(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:htjPzLKLLbRXxfKz9NUgMYMuIaY9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:FAFFFF942D6B0FBD|rigid:Us6yA+a/lpaSBB/u7ih8rsyUO6c	false	sufficient binding region:209-470(IPR001664)	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50570	uniprotkb:O95295	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664279|imex:IM-16425-693	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|genbank_protein_gi:56549124(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:AC35C771492E1863|rigid:lpMKzBlylDrXkRMCBkVf6DRjRR0	false	sufficient binding region:564-870	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q03001	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664296|imex:IM-16425-694	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	intact-crc:09B233A026CC0A8B|rigid:mWRL2tYdjx+bXyHWaFD+dZrpZsI	false	sufficient binding region:34-136	sufficient binding region:3794-7570(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q96EV8	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664314|imex:IM-16425-695	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|genbank_protein_gi:34304371(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	intact-crc:C7EE00722F1FB833|rigid:7II9Twtm8pjRg8rk/fNX4yQu6P8	false	sufficient binding region:34-136	sufficient binding region:90-351(IPR007531)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NV70	uniprotkb:O95295	intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514|ensembl:ENSP00000370695	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664332|imex:IM-16425-696	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|ensembl:ENSG00000090989(gene)|ensembl:ENST00000346134(transcript)|ensembl:ENST00000381295(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051607"(defense response to virus)|go:"GO:0090543"(Flemming body)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|interpro:IPR019160|interpro:IPR028258|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016863898.1|dip:DIP-37579N|genbank_protein_gi:67944633(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:F223B04CB0ABA9E4|rigid:0nzkoTCB7frO5lbAOHpL0ye1jwI	false	sufficient binding region:201-894	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q8IWE2	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-2686288|uniprotkb:Q6MZV4|uniprotkb:A8K9W6|uniprotkb:Q9BVL6|ensembl:ENSP00000351740	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:nxp20_human(display_long)|uniprotkb:NOXP20(gene name synonym)|uniprotkb:Protein FAM114A1(gene name synonym)|uniprotkb:FAM114A1(gene name)|psi-mi:FAM114A1(display_short)|uniprotkb:Nervous system overexpressed protein 20(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664349|imex:IM-16425-697	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:NP_612398.2|refseq:XP_005262729.1|ensembl:ENSG00000197712(gene)|ensembl:ENST00000358869(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|interpro:IPR007998(Protein of unknown function DUF719)|refseq:NP_001317693.1|genbank_protein_gi:29789372(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:LjjPhFyL25/vnOtP5bzZBjKIRxs9606	intact-crc:AC611B84BA660676|rigid:bjQURuHvlxo/DMJVG8V93Vp6kDY	false	sufficient binding region:34-136	sufficient binding region:295-563(IPR007998)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H6L5	uniprotkb:O95295	intact:EBI-5664372|uniprotkb:Q9H6K6|uniprotkb:Q9H764|uniprotkb:Q69YN8|uniprotkb:Q9NXM8|ensembl:ENSP00000304642	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:retr1_human(display_long)|uniprotkb:RETREG1(gene name)|psi-mi:RETREG1(display_short)|uniprotkb:FAM134B(gene name synonym)|uniprotkb:JK1(gene name synonym)|uniprotkb:Reticulophagy receptor 1(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664367|imex:IM-16425-698	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001030022.1|refseq:NP_061873.2|dip:DIP-61577N|ensembl:ENSG00000154153(gene)|ensembl:ENST00000306320(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0016604"(nuclear body)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0061709"(reticulophagy)|interpro:IPR033358|interpro:IPR043384|mint:Q9H6L5|rcsb pdb:7BRQ|genbank_protein_gi:77917616(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9IT3rARBCtNfCAkRklfhF3Q5bf09606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:8D84075CCCFE9216|rigid:k0sUgIWZQpKFZBIgC461wvVThWM	false	sufficient binding region:241-497..497	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:O95163	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-347559|uniprotkb:Q9H327|uniprotkb:Q9UG87|uniprotkb:Q5JSV2|ensembl:ENSP00000363779|ensembl:ENSP00000501893	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:elp1_human(display_long)|uniprotkb:ELP1(gene name)|psi-mi:ELP1(display_short)|uniprotkb:IKAP(gene name synonym)|uniprotkb:IKBKAP(gene name synonym)|uniprotkb:p150(gene name synonym)|uniprotkb:IkappaB kinase complex-associated protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664392|imex:IM-16425-699	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	dip:DIP-27579N|refseq:NP_003631.2|refseq:NP_001305289.1|ensembl:ENSG00000070061(gene)|ensembl:ENST00000374647(transcript)|ensembl:ENST00000675406(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR006849(IKI3)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:O95163|rcsb pdb:5CQR|reactome:R-HSA-3214847|go:"GO:0005829"(cytosol)|genbank_protein_gi:38569393(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:hl+inV6TcN+DGu9CwE3SitkHiI09606	intact-crc:E099DC75F8348392|rigid:vmjTmoDIavDryFBppE5piXaJpRI	false	sufficient binding region:34-136	sufficient binding region:1144-1332..1332	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14974	uniprotkb:O95295	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664409|imex:IM-16425-700	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249|genbank_protein_gi:24797084(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:BADF94640DDD8A11|rigid:X7joadWcQ4SZCv5QEdoyMaP1J3Y	false	sufficient binding region:186-876(IPR000225)	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	intact:EBI-5664428	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	-	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:krt10(display_short)|psi-mi:EBI-5664428(display_long)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664430|imex:IM-16425-701	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	uniprotkb:nd(uniprot-removed-ac)|genbank_protein_gi:40354191(identity)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	-	intact-crc:6E15812370110006	false	sufficient binding region:34-136	sufficient binding region:164-584(IPR001664)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q04695	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-297873|ensembl:ENSP00000308452|uniprotkb:A5Z1M9|uniprotkb:A5Z1N0|uniprotkb:A5Z1N1|uniprotkb:A5Z1N2|uniprotkb:A6NDV6|uniprotkb:A6NKQ2|uniprotkb:Q6IP98|uniprotkb:Q8N1P6	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:k1c17_human(display_long)|uniprotkb:KRT17(gene name)|psi-mi:KRT17(display_short)|uniprotkb:Cytokeratin-17(gene name synonym)|uniprotkb:39.1(gene name synonym)|uniprotkb:Keratin-17(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664449|imex:IM-16425-702	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	ensembl:ENSG00000128422(gene)|ensembl:ENST00000311208(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031424"(keratinization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0071944"(cell periphery)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:Q04695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_000413.1|dip:DIP-33093N|genbank_protein_gi:4557700(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:cwKlvMqhQGUokThbIxgEkB6Wzxw9606	intact-crc:A02FC4834D7402D9|rigid:vX+eKNcdjafSSut2zuoetgKenu4	false	sufficient binding region:34-136	sufficient binding region:114-432(IPR001664)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q04695	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-297873|ensembl:ENSP00000308452|uniprotkb:A5Z1M9|uniprotkb:A5Z1N0|uniprotkb:A5Z1N1|uniprotkb:A5Z1N2|uniprotkb:A6NDV6|uniprotkb:A6NKQ2|uniprotkb:Q6IP98|uniprotkb:Q8N1P6	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:k1c17_human(display_long)|uniprotkb:KRT17(gene name)|psi-mi:KRT17(display_short)|uniprotkb:Cytokeratin-17(gene name synonym)|uniprotkb:39.1(gene name synonym)|uniprotkb:Keratin-17(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664468|imex:IM-16425-703	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	ensembl:ENSG00000128422(gene)|ensembl:ENST00000311208(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031424"(keratinization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0071944"(cell periphery)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:Q04695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_000413.1|dip:DIP-33093N|genbank_protein_gi:4557700(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:cwKlvMqhQGUokThbIxgEkB6Wzxw9606	intact-crc:E23322ECEC184465|rigid:vX+eKNcdjafSSut2zuoetgKenu4	false	sufficient binding region:34-136	sufficient binding region:262-432(IPR001664)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P24043	uniprotkb:O95295	intact:EBI-2529730|uniprotkb:Q14736|uniprotkb:Q5VUM2|uniprotkb:Q93022|ensembl:ENSP00000400365	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:lama2_human(display_long)|uniprotkb:Laminin-2 subunit alpha(gene name synonym)|uniprotkb:Laminin-4 subunit alpha(gene name synonym)|uniprotkb:Laminin-12 subunit alpha(gene name synonym)|uniprotkb:LAMA2(gene name)|psi-mi:LAMA2(display_short)|uniprotkb:LAMM(gene name synonym)|uniprotkb:Laminin M chain(gene name synonym)|uniprotkb:Merosin heavy chain(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664487|imex:IM-16425-704	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000196569(gene)|ensembl:ENST00000421865(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042383"(sarcolemma)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043197"(dendritic spine)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|mint:P24043|rcsb pdb:4YEP|rcsb pdb:4YEQ|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-8874081|reactome:R-HSA-9619665|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_000417.2|refseq:NP_001073291.1|dip:DIP-42562N|genbank_protein_gi:119466531(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:z2F+5o5SCklBK+JoJkvTFZlOgNc9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:24E16BC18930E333|rigid:JBVMeDMpcxzwpfZC9WGjXRhtc/8	false	sufficient binding region:1738-3122	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:P11047	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-714904|uniprotkb:Q5VYE7|ensembl:ENSP00000258341	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:lamc1_human(display_long)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:LAMC1(gene name)|psi-mi:LAMC1(display_short)|uniprotkb:LAMB2(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664504|imex:IM-16425-705	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|mint:P11047|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9619665|go:"GO:0070062"(extracellular exosome)|refseq:NP_002284.3|ensembl:ENSG00000135862(gene)|ensembl:ENST00000258341(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007492"(endoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)|genbank_protein_gi:9845497(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:2JMPODzaiqmTaLlmjdgvlv8e8+M9606	intact-crc:DED3921DEBEC8CF4|rigid:RJsLTMTmMBPfw8wK8EPbHxZSwAU	false	sufficient binding region:34-136	sufficient binding region:1425-1609	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UPN3-5	uniprotkb:O95295	intact:EBI-6131019|intact:EBI-536284	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:q9upn3-5(display_long)|uniprotkb:MACF1(gene name)|psi-mi:MACF1(display_short)|uniprotkb:620 kDa actin-binding protein(gene name synonym)|uniprotkb:ABP620(gene name synonym)|uniprotkb:ACF7(gene name synonym)|uniprotkb:Actin cross-linking family protein 7(gene name synonym)|uniprotkb:KIAA0465(gene name synonym)|uniprotkb:KIAA1251(gene name synonym)|uniprotkb:Macrophin-1(gene name synonym)|uniprotkb:Trabeculin-alpha(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664521|imex:IM-16425-706	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-522925(isoform-parent)|genbank_protein_gi:33188442(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:eXp1bnAZeqXA66p9WWkiFxW3Ttk9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:D51F8B442B453479|rigid:zPLNriQUI5Kf5Pxct/UYj3jz55w	false	sufficient binding region:3151-5938	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q9UPN3-5	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-6131019|intact:EBI-536284	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:q9upn3-5(display_long)|uniprotkb:MACF1(gene name)|psi-mi:MACF1(display_short)|uniprotkb:620 kDa actin-binding protein(gene name synonym)|uniprotkb:ABP620(gene name synonym)|uniprotkb:ACF7(gene name synonym)|uniprotkb:Actin cross-linking family protein 7(gene name synonym)|uniprotkb:KIAA0465(gene name synonym)|uniprotkb:KIAA1251(gene name synonym)|uniprotkb:Macrophin-1(gene name synonym)|uniprotkb:Trabeculin-alpha(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664538|imex:IM-16425-707	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	intact:EBI-522925(isoform-parent)|genbank_protein_gi:33188442(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:eXp1bnAZeqXA66p9WWkiFxW3Ttk9606	intact-crc:F35A9FA8627C816E|rigid:zPLNriQUI5Kf5Pxct/UYj3jz55w	false	sufficient binding region:34-136	sufficient binding region:4452-5938	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q7Z406	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-355595|uniprotkb:Q5CZ75|uniprotkb:Q6XYE4|uniprotkb:Q76B62|uniprotkb:Q8WV23|uniprotkb:Q96I22|uniprotkb:Q9BT27|uniprotkb:Q9BW35|uniprotkb:Q9H882|uniprotkb:B0I1S2|ensembl:ENSP00000366169|ensembl:ENSP00000472819|uniprotkb:C3TTN4	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:myh14_human(display_long)|uniprotkb:MYH14(gene name)|psi-mi:MYH14(display_short)|uniprotkb:KIAA2034(gene name synonym)|uniprotkb:FP17425(orf name)|uniprotkb:Myosin heavy chain 14(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIc(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIc(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664555|imex:IM-16425-708	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:NP_001070654.1|refseq:NP_001139281.1|refseq:NP_079005.3|refseq:XP_011525625.1|ensembl:ENSG00000105357(gene)|ensembl:ENST00000376970(transcript)|ensembl:ENST00000596571(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030426"(growth cone)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097513"(myosin II filament)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q7Z406|rcsb pdb:5I4E|rcsb pdb:5JLH|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|interpro:IPR002928(Myosin tail)|refseq:XP_006723449.1|dip:DIP-33170N|genbank_protein_gi:116284395(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:6aY3HPa5DIY5UadiOTTh/uSPi/M9606	intact-crc:77442AC32B6DD496|rigid:pQNc5qoS0xpkGtcohIh0FH7no+k	false	sufficient binding region:34-136	sufficient binding region:1501-1995(IPR002928)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:P11055	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664573|imex:IM-16425-709	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	intact-crc:A30BA764CD5D285A|rigid:c3Qm6y4WuH6NonW7AeY8leZsjFk	false	sufficient binding region:34-136	sufficient binding region:1337-1940(IPR002928)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:P11055	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664591|imex:IM-16425-710	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	intact-crc:021A42FAE7F817BB|rigid:c3Qm6y4WuH6NonW7AeY8leZsjFk	false	sufficient binding region:34-136	sufficient binding region:1514-1940(IPR002928)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12883	uniprotkb:O95295	intact:EBI-519141|uniprotkb:Q14836|uniprotkb:Q14837|uniprotkb:Q14904|uniprotkb:Q16579|uniprotkb:Q2M1Y6|uniprotkb:Q92679|uniprotkb:Q9H1D5|ensembl:ENSP00000347507|uniprotkb:Q9UMM8|uniprotkb:A2TDB6|uniprotkb:B6D424|uniprotkb:Q9UDA2	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:myh7_human(display_long)|uniprotkb:Myosin heavy chain 7(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle beta isoform(gene name synonym)|uniprotkb:Myosin heavy chain slow isoform(gene name synonym)|uniprotkb:MYH7(gene name)|psi-mi:MYH7(display_short)|uniprotkb:MYHCB(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664609|imex:IM-16425-711	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092054(gene)|ensembl:ENST00000355349(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031449"(regulation of slow-twitch skeletal muscle fiber contraction)|go:"GO:0032982"(myosin filament)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P12883|rcsb pdb:1IK2|rcsb pdb:2FXM|rcsb pdb:2FXO|rcsb pdb:3DTP|rcsb pdb:4DB1|rcsb pdb:4P7H|rcsb pdb:4PA0|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA4|rcsb pdb:4XA6|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ1|rcsb pdb:5CJ4|rcsb pdb:5TBY|rcsb pdb:5WJ7|rcsb pdb:5WJB|rcsb pdb:5WLQ|rcsb pdb:5WLZ|rcsb pdb:5WME|rcsb pdb:6PF2|rcsb pdb:6PFP|refseq:NP_000248.2|refseq:XP_016876829.1|genbank_protein_gi:115496168(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Fz6cO12gihAyDMe06hLrQbrupbs9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:002129A6BCD42C16|rigid:EWsdDehQ0e3ZW9E5kB7Ur7Vb8aM	false	sufficient binding region:1272-1935	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:P12883	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-519141|uniprotkb:Q14836|uniprotkb:Q14837|uniprotkb:Q14904|uniprotkb:Q16579|uniprotkb:Q2M1Y6|uniprotkb:Q92679|uniprotkb:Q9H1D5|ensembl:ENSP00000347507|uniprotkb:Q9UMM8|uniprotkb:A2TDB6|uniprotkb:B6D424|uniprotkb:Q9UDA2	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:myh7_human(display_long)|uniprotkb:Myosin heavy chain 7(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle beta isoform(gene name synonym)|uniprotkb:Myosin heavy chain slow isoform(gene name synonym)|uniprotkb:MYH7(gene name)|psi-mi:MYH7(display_short)|uniprotkb:MYHCB(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664626|imex:IM-16425-712	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	ensembl:ENSG00000092054(gene)|ensembl:ENST00000355349(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031449"(regulation of slow-twitch skeletal muscle fiber contraction)|go:"GO:0032982"(myosin filament)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P12883|rcsb pdb:1IK2|rcsb pdb:2FXM|rcsb pdb:2FXO|rcsb pdb:3DTP|rcsb pdb:4DB1|rcsb pdb:4P7H|rcsb pdb:4PA0|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA4|rcsb pdb:4XA6|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ1|rcsb pdb:5CJ4|rcsb pdb:5TBY|rcsb pdb:5WJ7|rcsb pdb:5WJB|rcsb pdb:5WLQ|rcsb pdb:5WLZ|rcsb pdb:5WME|rcsb pdb:6PF2|rcsb pdb:6PFP|refseq:NP_000248.2|refseq:XP_016876829.1|genbank_protein_gi:115496168(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:Fz6cO12gihAyDMe06hLrQbrupbs9606	intact-crc:C33AC274D06E45F1|rigid:EWsdDehQ0e3ZW9E5kB7Ur7Vb8aM	false	sufficient binding region:34-136	sufficient binding region:1466-1935	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14511	uniprotkb:O95295	intact:EBI-2108053|uniprotkb:Q5T9R4|uniprotkb:A8K9G7|uniprotkb:G5E9Y9|uniprotkb:A8MSJ9|uniprotkb:Q5XKI0|intact:EBI-28980032|ensembl:ENSP00000368759	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:casl_human(display_long)|uniprotkb:NEDD9(gene name)|psi-mi:NEDD9(display_short)|uniprotkb:CASL(gene name synonym)|uniprotkb:CASS2(gene name synonym)|uniprotkb:CRK-associated substrate-related protein(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 9(gene name synonym)|uniprotkb:Cas scaffolding protein family member 2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-12(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664643|imex:IM-16425-713	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006394.1|refseq:NP_892011.2|refseq:NP_001135865.1|ensembl:ENST00000379433|ensembl:ENSP00000368745|ensembl:ENSP00000368759|ensembl:ENST00000504387|ensembl:ENSP00000422871|refseq:NP_001257962.1|interpro:IPR035746|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:Q14511|rcsb pdb:2L81|rcsb pdb:5X3S|ensembl:ENSG00000111859(gene)|ensembl:ENST00000379446(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0040008"(regulation of growth)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051301"(cell division)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|genbank_protein_gi:33667045(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3PsYJXDgAihLYOOwKMBtDhQZQkU9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:EBC2ECA0CBA510EC|rigid:fnmXqxlZfKI0ERetX/7Hn8IqoWk	false	sufficient binding region:553-834	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15149	uniprotkb:O95295	intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|ensembl:ENSP00000323856|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664660|imex:IM-16425-714	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|interpro:IPR030269|interpro:IPR035915|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|ensembl:ENST00000436759|ensembl:ENSP00000388180|ensembl:ENST00000527096|ensembl:ENSP00000434583|ensembl:ENSP00000323856|ensembl:ENST00000345136|ensembl:ENSP00000344848|ensembl:ENST00000354589|ensembl:ENSP00000346602|ensembl:ENST00000354958|ensembl:ENSP00000347044|ensembl:ENST00000356346|ensembl:ENSP00000348702|ensembl:ENST00000357649|ensembl:ENSP00000350277|ensembl:ENST00000398774|ensembl:ENSP00000381756|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1|genbank_protein_gi:40849943(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:FE984AB578A145BB|rigid:9R+Gt3cFRnPXA0QE3G8ZaZxSYi0	false	sufficient binding region:199-4684	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15276	uniprotkb:O95295	intact:EBI-447043|uniprotkb:O95369|uniprotkb:Q8IVX3|uniprotkb:B2RAG7|ensembl:ENSP00000445408	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:rabe1_human(display_long)|uniprotkb:Rabaptin-5(gene name synonym)|uniprotkb:Rabaptin-5alpha(gene name synonym)|uniprotkb:Rabaptin-4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-17(gene name synonym)|uniprotkb:RABEP1(gene name)|psi-mi:RABEP1(display_short)|uniprotkb:RABPT5(gene name synonym)|uniprotkb:RABPT5A(gene name synonym)|uniprotkb:RAB5EP(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664677|imex:IM-16425-715	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278510.1|refseq:NP_001077054.1|refseq:NP_004694.2|dip:DIP-29350N|go:"GO:0008083"(growth factor activity)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR003914(Rabaptin)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR018514|interpro:IPR029880|rcsb pdb:1P4U|rcsb pdb:1TU3|rcsb pdb:1X79|rcsb pdb:4N3Y|rcsb pdb:4N3Z|rcsb pdb:4Q9U|reactome:R-HSA-8854214|ensembl:ENSG00000029725(gene)|ensembl:ENST00000537505(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|genbank_protein_gi:49574500(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:FDHgN8w6jbAPC3iQfeLY6sdLkrs9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:A48DD5F339E04E5D|rigid:t0g7qHiNVRaDpJ3WxmAVSgShs/E	false	sufficient binding region:485-862(IPR003914)	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJ41	uniprotkb:O95295	intact:EBI-913954|uniprotkb:B4DZM7|uniprotkb:Q3HKR2|uniprotkb:Q3HKR3|uniprotkb:Q53FG0|ensembl:ENSP00000284957|ensembl:ENSP00000415815	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:rabx5_human(display_long)|uniprotkb:Rabex-5(gene name synonym)|uniprotkb:Rabaptin-5-associated exchange factor for Rab5(gene name synonym)|uniprotkb:RAP1(gene name synonym)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)|uniprotkb:RABEX5(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664695|imex:IM-16425-716	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154710(gene)|ensembl:ENST00000284957(transcript)|ensembl:ENST00000450873(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0055037"(recycling endosome)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|rcsb pdb:1TXU|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2OT3|rcsb pdb:4N3X|rcsb pdb:4N3Y|rcsb pdb:4N3Z|rcsb pdb:4Q9U|reactome:R-HSA-8854214|reactome:R-HSA-8876198|refseq:NP_055319.1|refseq:NP_001273989.1|refseq:NP_001273990.1|refseq:NP_001273991.1|dip:DIP-29348N|genbank_protein_gi:7657495(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2019/05/28	rogid:+MNigZ2IH2ogPAFA5YTYT0rGWYg9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:6A8E52F219F11E37|rigid:3xSOLCVoNLFtMDNdBCVxHgitqSI	false	sufficient binding region:?-?(IPR003123)	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q96Q15	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-1049832|uniprotkb:O43305|uniprotkb:Q13284|uniprotkb:Q8NFX2|uniprotkb:Q96QV0|uniprotkb:Q96RW3|ensembl:ENSP00000402515	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:smg1_human(display_long)|uniprotkb:Lambda/iota protein kinase C-interacting protein(gene name synonym)|uniprotkb:61E3.4(gene name synonym)|uniprotkb:SMG1(gene name)|psi-mi:SMG1(display_short)|uniprotkb:ATX(gene name synonym)|uniprotkb:KIAA0421(gene name synonym)|uniprotkb:LIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664713|imex:IM-16425-717	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:NP_055907.3|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR031559|interpro:IPR035175|interpro:IPR036940|interpro:IPR039414|mint:Q96Q15|rcsb pdb:6L53|rcsb pdb:6L54|rcsb pdb:6SYT|rcsb pdb:6Z3R|reactome:R-HSA-975957|ensembl:ENSG00000157106(gene)|ensembl:ENST00000446231(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032204"(regulation of telomere maintenance)|genbank_protein_gi:62243657(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:u7doCYezlcCUKq//xhk0TZ2TD009606	intact-crc:C889FFF2482DC40A|rigid:Kplm6IEL5zXbj8M+FIEG8yZ/62k	false	sufficient binding region:34-136	sufficient binding region:2433-3661	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11277	uniprotkb:O95295	intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664730|imex:IM-16425-718	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|genbank_protein_gi:67782318(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:917BE3B1DB876104|rigid:NtGeSwUVTk+CM6OrJAgkKKODN6A	false	sufficient binding region:788-2137(IPR002017)	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11277	uniprotkb:O95295	intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664748|imex:IM-16425-719	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|genbank_protein_gi:67782318(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:D595F774782435C2|rigid:NtGeSwUVTk+CM6OrJAgkKKODN6A	false	sufficient binding region:1-2137(IPR001715)	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11277	uniprotkb:O95295	intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664767|imex:IM-16425-720	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|genbank_protein_gi:67782318(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:FC22B36A45F8BC55|rigid:NtGeSwUVTk+CM6OrJAgkKKODN6A	false	sufficient binding region:663-2137(IPR002017)	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:Q01082	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664785|imex:IM-16425-721	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N|genbank_protein_gi:112382251(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606	intact-crc:0D26F9AE256569EB|rigid:CsXizR1Ozvx1Ia99tkIHP1A3aYg	false	sufficient binding region:34-136	sufficient binding region:1708-2364	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94826	uniprotkb:O95295	intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664802|imex:IM-16425-722	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020|genbank_protein_gi:54607134(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:6E3A7576FEE85E10|rigid:i3tueSlg1AsCmb8qY45GbijC7m4	false	sufficient binding region:379-608	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:P09493	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-351158|uniprotkb:P09494|uniprotkb:P10469|uniprotkb:Q86W64|uniprotkb:Q96IK2|uniprotkb:Q9Y427|uniprotkb:Q9UCY9|uniprotkb:Q6DV89|uniprotkb:Q6DV90|uniprotkb:Q9UCI1|uniprotkb:Q9UCI2|uniprotkb:B7Z5T7|uniprotkb:Q7Z6L8|intact:EBI-2558177|ensembl:ENSP00000385107|intact:EBI-11030042|uniprotkb:D9YZV2|uniprotkb:D9YZV3|uniprotkb:D9YZV8	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:tpm1_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664819|imex:IM-16425-723	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:NP_000357.3|refseq:NP_001018005.1|refseq:NP_001018006.1|refseq:NP_001018008.1|ensembl:ENSG00000140416(gene)|ensembl:ENST00000403994(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|mint:P09493|rcsb pdb:3MUD|rcsb pdb:5KHT|rcsb pdb:6UT2|rcsb pdb:6X5Z|reactome:R-HSA-390522|reactome:R-HSA-445355|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001288173.1|refseq:NP_001018007.1|refseq:NP_001018004.1|refseq:NP_001018020.1|refseq:XP_016878027.1|refseq:NP_001317273.1|refseq:NP_001317275.1|refseq:NP_001317280.1|genbank_protein_gi:63252897(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:rsKuZnKpbEqVOpYBz3PnoSBCSHs9606	intact-crc:9FAD207A813B0CD8|rigid:UgwVlxqTx9Z6iGoN0sx+VLu2fHw	false	sufficient binding region:34-136	sufficient binding region:79-284(IPR000533)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:P07951	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-352633|uniprotkb:P06468|uniprotkb:Q13894|uniprotkb:Q53FM4|uniprotkb:A6NM85|uniprotkb:Q5TCU4|uniprotkb:Q5TCU7|uniprotkb:Q9UH67|ensembl:ENSP00000496494	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:tpm2_human(display_long)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short)|uniprotkb:TMSB(gene name synonym)|uniprotkb:Tropomyosin-2(gene name synonym)|uniprotkb:Beta-tropomyosin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664837|imex:IM-16425-724	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:NP_003280.2|refseq:NP_998839.1|mint:P07951|reactome:R-HSA-390522|reactome:R-HSA-445355|ensembl:ENSG00000198467(gene)|ensembl:ENST00000645482(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR000533(Tropomyosin)|refseq:XP_016870580.1|genbank_protein_gi:47519592(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:uMqEpVZJ9ezKmeA67qQLCWBd/zo9606	intact-crc:E3633B3660306225|rigid:rtR35T27je8koRbEy1cCwF1J/3g	false	sufficient binding region:34-136	sufficient binding region:176-284(IPR000533)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07951	uniprotkb:O95295	intact:EBI-352633|uniprotkb:P06468|uniprotkb:Q13894|uniprotkb:Q53FM4|uniprotkb:A6NM85|uniprotkb:Q5TCU4|uniprotkb:Q5TCU7|uniprotkb:Q9UH67|ensembl:ENSP00000496494	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:tpm2_human(display_long)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short)|uniprotkb:TMSB(gene name synonym)|uniprotkb:Tropomyosin-2(gene name synonym)|uniprotkb:Beta-tropomyosin(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664855|imex:IM-16425-725	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003280.2|refseq:NP_998839.1|mint:P07951|reactome:R-HSA-390522|reactome:R-HSA-445355|ensembl:ENSG00000198467(gene)|ensembl:ENST00000645482(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR000533(Tropomyosin)|refseq:XP_016870580.1|genbank_protein_gi:47519592(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:uMqEpVZJ9ezKmeA67qQLCWBd/zo9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:2496177E3A60C6FB|rigid:rtR35T27je8koRbEy1cCwF1J/3g	false	sufficient binding region:91-284(IPR000533)	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969Q1	uniprotkb:O95295	intact:EBI-5661333|uniprotkb:Q9BYV4|uniprotkb:Q96BD3|uniprotkb:Q96KD9|uniprotkb:Q5T2I1|uniprotkb:B4DN95|ensembl:ENSP00000363390	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:tri63_human(display_long)|uniprotkb:IRF(gene name synonym)|uniprotkb:Iris RING finger protein(gene name synonym)|uniprotkb:MURF1(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 28(gene name synonym)|uniprotkb:RNF28(gene name synonym)|uniprotkb:SMRZ(gene name synonym)|uniprotkb:Striated muscle RING zinc finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 63(gene name synonym)|uniprotkb:TRIM63(gene name)|psi-mi:TRIM63(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM63(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664873|imex:IM-16425-726	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115977.2|ensembl:ENSG00000158022(gene)|ensembl:ENST00000374272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR042667|mint:Q969Q1|rcsb pdb:2D8U|rcsb pdb:3DDT|rcsb pdb:4M3L|reactome:R-HSA-9615017|reactome:R-HSA-983168|genbank_protein_gi:19924162(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:fxaNyoTJdzJyjJb+QYEZ+d72DbA9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:23B835641B5C727E|rigid:HTgUKKPI1hfVhnVqWN6n/qBbSPQ	false	sufficient binding region:217-353	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:P62258	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664890|imex:IM-16425-727	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447|genbank_protein_gi:34304385(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	intact-crc:490DF68F00F760A8|rigid:+32oD7yqIiFe0m/v2uHJFM/Zj2s	false	sufficient binding region:34-136	sufficient binding region:1-255	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63104	uniprotkb:O95295	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664907|imex:IM-16425-728	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|genbank_protein_gi:80477444(identity)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1|genbank_protein_gi:39725677(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:BF20AE9B063F6401|rigid:n+f683uQrtXHjg9oHgJjGO9F9H0	false	sufficient binding region:1-245	sufficient binding region:34-136	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0K7	uniprotkb:Q9Y376	intact:EBI-306893|uniprotkb:Q5BKY7|uniprotkb:Q9P1L0|ensembl:ENSP00000194530	intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7	psi-mi:strab_human(display_long)|uniprotkb:STRADB(gene name)|psi-mi:STRADB(display_short)|uniprotkb:ILPIP(gene name synonym)|uniprotkb:Pseudokinase ALS2CR2(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein(gene name synonym)|uniprotkb:ALS2CR2(gene name synonym)|uniprotkb:ILP-interacting protein(gene name synonym)|uniprotkb:CALS-21(gene name synonym)|uniprotkb:PRO1038(orf name)	psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664924|imex:IM-16425-729	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193793.1|refseq:NP_061041.2|refseq:XP_016859927.1|ensembl:ENSG00000082146(gene)|ensembl:ENST00000194530(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007254"(JNK cascade)|go:"GO:0016235"(aggresome)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|reactome:R-HSA-380972|genbank_protein_gi:21359970(identity)	go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|genbank_protein_gi:7706481(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0oXeswkNLoFV4PTC1f9DYRKJpVk9606	rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606	intact-crc:DDA7EBA3232DD240|rigid:nu600MQ+83BOTUn4u6DMqcx/Hhk	false	sufficient binding region:1-418	sufficient binding region:1-341	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20929	uniprotkb:Q9C0K7	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	intact:EBI-306893|uniprotkb:Q5BKY7|uniprotkb:Q9P1L0|ensembl:ENSP00000194530	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:strab_human(display_long)|uniprotkb:STRADB(gene name)|psi-mi:STRADB(display_short)|uniprotkb:ILPIP(gene name synonym)|uniprotkb:Pseudokinase ALS2CR2(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein(gene name synonym)|uniprotkb:ALS2CR2(gene name synonym)|uniprotkb:ILP-interacting protein(gene name synonym)|uniprotkb:CALS-21(gene name synonym)|uniprotkb:PRO1038(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664941|imex:IM-16425-730	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028|genbank_protein_gi:115527119(identity)	refseq:NP_001193793.1|refseq:NP_061041.2|refseq:XP_016859927.1|ensembl:ENSG00000082146(gene)|ensembl:ENST00000194530(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007254"(JNK cascade)|go:"GO:0016235"(aggresome)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|reactome:R-HSA-380972|genbank_protein_gi:21359970(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rogid:0oXeswkNLoFV4PTC1f9DYRKJpVk9606	intact-crc:157CBE9480DDF667|rigid:JST6gZtJDoAdbjfO/nAovypivOk	false	sufficient binding region:5323-6669	sufficient binding region:1-418	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15273	uniprotkb:Q9BRR6	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	intact:EBI-723761|uniprotkb:Q49AU7|uniprotkb:Q8NBI1|uniprotkb:Q8WZ90|uniprotkb:Q96NF8|uniprotkb:Q9H0A7|ensembl:ENSP00000397694	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:adpgk_human(display_long)|uniprotkb:RbBP-35(gene name synonym)|uniprotkb:ADPGK(gene name)|psi-mi:ADPGK(display_short)|uniprotkb:PSEC0260(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664958|imex:IM-16425-731	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	refseq:NP_112574.3|refseq:XP_006720775.1|ensembl:ENSG00000159322(gene)|ensembl:ENST00000456471(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0043843"(ADP-specific glucokinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0061620"(glycolytic process through glucose-6-phosphate)|interpro:IPR007666(ADP-specific phosphofructokinase/glucokinase)|mint:Q9BRR6|reactome:R-HSA-70171|interpro:IPR029056|genbank_protein_gi:31542508(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	rogid:jeRKymflPO3JABiI6J42cZZEbwc9606	intact-crc:FAC713FA82B6BD59|rigid:UAZTKSsiixJjBp4prsWEiwIKpyM	false	sufficient binding region:1-167	sufficient binding region:271-497..497	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54253	uniprotkb:O15273	intact:EBI-930964|uniprotkb:Q17S02|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|ensembl:ENSP00000244769|ensembl:ENSP00000416360	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664975|imex:IM-16425-732	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000323.2|refseq:NP_001121636.1|dip:DIP-35353N|ensembl:ENSG00000124788(gene)|ensembl:ENST00000244769(transcript)|ensembl:ENST00000436367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016363"(nuclear matrix)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035176"(social behavior)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051168"(nuclear export)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR036096|interpro:IPR040172|interpro:IPR043404|mint:P54253|rcsb pdb:1OA8|rcsb pdb:2M41|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6QIU|genbank_protein_gi:51479157(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:BE1EE5D813D8A034|rigid:Os6Fwmqu5wezZlvLI0rGlfT578Y	false	sufficient binding region:599-815(IPR003652)	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHD1	uniprotkb:O15273	intact:EBI-2550959|ensembl:ENSP00000319255|ensembl:ENSP00000496744|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5664993|imex:IM-16425-733	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000320585(transcript)|ensembl:ENST00000646618(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0043531"(ADP binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|rcsb pdb:2YRT|go:"GO:1900034"(regulation of cellular response to heat)|refseq:NP_001137545.1|refseq:NP_036256.2|genbank_protein_gi:47940671(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:0EFE84409A5D0464|rigid:8GWoiWb2TjVrF0ES7SEqQbPKfpw	false	sufficient binding region:199-332..332(IPR007052)	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:O15273	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665012|imex:IM-16425-734	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:54E11EC40D85A697|rigid:QmrAS/ITSpG1uebNvXyl4mkw944	false	sufficient binding region:141-434(IPR000941)	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15273	uniprotkb:P13929	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665030|imex:IM-16425-735	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:33878987(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	intact-crc:9EB0A35457849D24|rigid:KmnKbbxJIg3Y+MBytEOEbIo4E2o	false	sufficient binding region:1-167	sufficient binding region:158-434(IPR000941)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15273	uniprotkb:O43504	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665048|imex:IM-16425-736	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	refseq:NP_006393.2|ensembl:ENSG00000134248(gene)|ensembl:ENST00000602318(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019079"(viral genome replication)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0061462"(protein localization to lysosome)|dip:DIP-61482N|genbank_protein_gi:38512187(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:907393D2A5A8CFAD|rigid:TMrD/J6j+ZrhogQ9gqRt/BZdiZo	false	sufficient binding region:1-167	sufficient binding region:1-91..91	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11142	uniprotkb:O15273	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665065|imex:IM-16425-737	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|genbank_protein_gi:24234684(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:692E8E5EFB3F8A20|rigid:drIe5uLJ6F+pQrYpIpbCggu2W9w	false	sufficient binding region:336-646(IPR001023)	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12988	uniprotkb:O15273	intact:EBI-713442|ensembl:ENSP00000303394	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:hspb3_human(display_long)|uniprotkb:Heat shock 17 kDa protein(gene name synonym)|uniprotkb:HSPB3(gene name)|psi-mi:HSPB3(display_short)|uniprotkb:HSPL27(gene name synonym)|uniprotkb:HSP27(gene name synonym)|uniprotkb:Protein 3(gene name synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665083|imex:IM-16425-738	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169271(gene)|ensembl:ENST00000302005(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016607"(nuclear speck)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR033894|rcsb pdb:6F2R|refseq:NP_006299.1|genbank_protein_gi:5453687(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:g8JQ9Pld5s4HQdM+yJrMv7qgf+Y9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:7B65ED63B8878FC0|rigid:bumHzw1Umu/184iswOr4tYJEM94	false	sufficient binding region:71-150..150(IPR002068)	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98160	uniprotkb:O15273	intact:EBI-947664|uniprotkb:Q16287|uniprotkb:Q9H3V5|uniprotkb:Q5SZI3|ensembl:ENSP00000363827	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:pgbm_human(display_long)|uniprotkb:Perlecan(gene name synonym)|uniprotkb:HSPG2(gene name)|psi-mi:HSPG2(display_short)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665102|imex:IM-16425-739	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278789.1|refseq:NP_005520.4|ensembl:ENSG00000142798(gene)|ensembl:ENST00000374695(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030021"(extracellular matrix structural constituent conferring compression resistance)|go:"GO:0030154"(cell differentiation)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072359"(circulatory system development)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR000034(Laminin B)|interpro:IPR000082(SEA)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR023415|interpro:IPR036055|interpro:IPR036179|mint:P98160|rcsb pdb:3SH4|rcsb pdb:3SH5|reactome:R-HSA-1474228|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-975634|reactome:R-HSA-977225|genbank_protein_gi:126012570(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5ctWru2Fde+1Twjd9B7u24hsIKY9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:149C38AB5D14411E|rigid:IVDZ8OfNVTGY/oFODOIEf+y6bNU	false	sufficient binding region:3405-4391	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60662	uniprotkb:O15273	intact:EBI-5353084|uniprotkb:Q53R42|ensembl:ENSP00000284669	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:klh41_human(display_long)|uniprotkb:KLHL41(gene name)|psi-mi:KLHL41(display_short)|uniprotkb:KBTBD10(gene name synonym)|uniprotkb:KRP1(gene name synonym)|uniprotkb:Kel-like protein 23(gene name synonym)|uniprotkb:Kelch repeat and BTB domain-containing protein 10(gene name synonym)|uniprotkb:Kelch-related protein 1(gene name synonym)|uniprotkb:Sarcosin(gene name synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665119|imex:IM-16425-740	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006054.2|ensembl:ENSG00000239474(gene)|ensembl:ENST00000284669(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031143"(pseudopodium)|go:"GO:0031275"(obsolete regulation of lateral pseudopodium assembly)|go:"GO:0031430"(M band)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030571|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:33873545(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:JwxQ7EGj03XUaJGeABl4ks7Vir89606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:EED52FD449E4A4A5|rigid:NZEZxSAHz/uW7KQDVRXfxL38Ew4	false	sufficient binding region:339-606	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15273	uniprotkb:Q00987	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	intact:EBI-389668|intact:EBI-28980679|ensembl:ENSP00000444430|uniprotkb:A6NL51|uniprotkb:Q13226|uniprotkb:Q13297|uniprotkb:Q13298|uniprotkb:Q13299|uniprotkb:Q13300|uniprotkb:Q13301|uniprotkb:Q53XW0|uniprotkb:Q71TW9|uniprotkb:Q8WYJ1|uniprotkb:Q8WYJ2|uniprotkb:Q9UGI3|uniprotkb:Q9UMT8|uniprotkb:A8K2S6	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:mdm2_human(display_long)|uniprotkb:MDM2(gene name)|psi-mi:MDM2(display_short)|uniprotkb:p53-binding protein Mdm2(gene name synonym)|uniprotkb:Oncoprotein Mdm2(gene name synonym)|uniprotkb:Double minute 2 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Mdm2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665136|imex:IM-16425-741	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	ensembl:ENSG00000135679(gene)|ensembl:ENST00000539479(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001568"(blood vessel development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002039"(p53 binding)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENST00000258149|ensembl:ENSP00000258149|ensembl:ENST00000299252|ensembl:ENSP00000299252|ensembl:ENST00000360430|ensembl:ENSP00000353611|ensembl:ENST00000393413|ensembl:ENSP00000377065|ensembl:ENSP00000444430|refseq:NP_001138811.1|refseq:NP_001265391.1|refseq:NP_002383.2|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043278"(response to morphine)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045472"(response to ether)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010039"(response to iron ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0036369"(transcription factor catabolic process)|refseq:XP_005268929.1|refseq:XP_006719462.1|go:"GO:0071301"(cellular response to vitamin B1)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904404"(response to formaldehyde)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990785"(response to water-immersion restraint stress)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015459(Ubiquitin-protein ligase E3 MDM2)|interpro:IPR016495(p53 negative regulator Mdm2/Mdm4)|interpro:IPR028340|interpro:IPR036443|interpro:IPR036885|interpro:IPR044080|mint:Q00987|rcsb pdb:1RV1|rcsb pdb:1T4E|rcsb pdb:1T4F|rcsb pdb:1YCR|rcsb pdb:1Z1M|rcsb pdb:2AXI|rcsb pdb:2C6A|rcsb pdb:2C6B|rcsb pdb:2F1Y|rcsb pdb:2FOP|rcsb pdb:2GV2|rcsb pdb:2HDP|rcsb pdb:2LZG|rcsb pdb:2M86|rcsb pdb:2MPS|rcsb pdb:2RUH|rcsb pdb:2VJE|rcsb pdb:2VJF|rcsb pdb:3EQS|rcsb pdb:3G03|rcsb pdb:3IUX|rcsb pdb:3IWY|rcsb pdb:3JZK|rcsb pdb:3JZR|rcsb pdb:3JZS|rcsb pdb:3LBK|rcsb pdb:3LBL|rcsb pdb:3LNJ|rcsb pdb:3LNZ|rcsb pdb:3MQS|rcsb pdb:3TJ2|rcsb pdb:3TPX|rcsb pdb:3TU1|rcsb pdb:3V3B|rcsb pdb:3VBG|rcsb pdb:3VZV|rcsb pdb:3W69|rcsb pdb:4DIJ|rcsb pdb:4ERE|rcsb pdb:4ERF|rcsb pdb:4HBM|rcsb pdb:4HFZ|rcsb pdb:4HG7|rcsb pdb:4JV7|rcsb pdb:4JV9|rcsb pdb:4JVE|rcsb pdb:4JVR|rcsb pdb:4JWR|rcsb pdb:4MDN|rcsb pdb:4MDQ|rcsb pdb:4OAS|rcsb pdb:4OBA|rcsb pdb:4OCC|rcsb pdb:4ODE|rcsb pdb:4ODF|rcsb pdb:4OGN|rcsb pdb:4OGT|rcsb pdb:4OGV|rcsb pdb:4OQ3|rcsb pdb:4QO4|rcsb pdb:4QOC|rcsb pdb:4UD7|rcsb pdb:4UE1|rcsb pdb:4XXB|rcsb pdb:4ZFI|rcsb pdb:4ZGK|rcsb pdb:4ZYC|rcsb pdb:4ZYF|rcsb pdb:4ZYI|rcsb pdb:5AFG|rcsb pdb:5HMH|rcsb pdb:5HMI|rcsb pdb:5HMK|rcsb pdb:5J7F|rcsb pdb:5J7G|rcsb pdb:5LAV|rcsb pdb:5LAW|rcsb pdb:5C5A|rcsb pdb:5LAY|rcsb pdb:5LAZ|rcsb pdb:5LN2|rcsb pdb:5MNJ|rcsb pdb:5OAI|rcsb pdb:5OC8|rcsb pdb:5SWK|rcsb pdb:5TRF|rcsb pdb:5UMM|rcsb pdb:5VK0|rcsb pdb:5WTS|rcsb pdb:5XXK|rcsb pdb:5Z02|rcsb pdb:5ZXF|rcsb pdb:6AAW|rcsb pdb:6GGN|rcsb pdb:6H22|rcsb pdb:6HFA|rcsb pdb:6I29|rcsb pdb:6I3S|rcsb pdb:6IM9|rcsb pdb:6KZU|rcsb pdb:6Q96|rcsb pdb:6Q9H|rcsb pdb:6Q9L|rcsb pdb:6Q9O|rcsb pdb:6SQO|rcsb pdb:6T2D|rcsb pdb:6T2E|rcsb pdb:6T2F|rcsb pdb:6Y4Q|rcsb pdb:7AD0|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BIR|rcsb pdb:7BIT|rcsb pdb:7BIV|rcsb pdb:7BJ0|rcsb pdb:7BJ6|rcsb pdb:7BMG|reactome:R-HSA-198323|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-399719|reactome:R-HSA-5674400|reactome:R-HSA-5689880|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69541|reactome:R-HSA-8941858|rcsb pdb:4UMN|rcsb pdb:4WT2|dip:DIP-392N|genbank_protein_gi:46488903(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	rogid:CFy2L9Et1jFtlApOFn2AKiGPWJ89606	intact-crc:D0D46C799399F131|rigid:oZW62GcXLajJTJy5fXCONcjUk4A	false	sufficient binding region:1-167	sufficient binding region:7-491(IPR003121)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WUM0	uniprotkb:O15273	intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665154|imex:IM-16425-742	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|genbank_protein_gi:26051234(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:F4893A9E24410D8C|rigid:4oJ+t8I0C/LDuWOCkUHhGXNEKig	false	sufficient binding region:69-1156	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23759-1	uniprotkb:O15273	intact:EBI-10909451|ensembl:ENSP00000364524	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:p23759-1(display_long)|uniprotkb:PAX7(gene name)|psi-mi:PAX7(display_short)|uniprotkb:HUP1(gene name synonym)|uniprotkb:HuP1(gene name synonym)|uniprotkb:Long(isoform synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665171|imex:IM-16425-743	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1042757(isoform-parent)|ensembl:ENSG00000009709(gene)|ensembl:ENST00000375375(transcript)|genbank_protein_gi:4505618(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2015/07/17	rogid:AtDWrJAzwk3FT4Kmg5pOstfT7WM9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:E609F0C52D4CBFB7|rigid:FFatjn4y3R3pl07zMm88hxbcnD8	false	sufficient binding region:118-520	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15273	uniprotkb:Q6DKK2	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	intact:EBI-948354|ensembl:ENSP00000261647|uniprotkb:Q7L3U8|uniprotkb:Q9NXB2|uniprotkb:A8MZ52|uniprotkb:B3KP62|uniprotkb:B4DN65|uniprotkb:Q9H6G3|uniprotkb:Q2M248	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:ttc19_human(display_long)|uniprotkb:TTC19(gene name)|psi-mi:TTC19(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665188|imex:IM-16425-744	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	ensembl:ENSG00000011295(gene)|ensembl:ENST00000261647(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005813"(centrosome)|go:"GO:0030496"(midbody)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0070469"(respirasome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040395|mint:Q6DKK2|refseq:NP_001258349.1|refseq:NP_060245.3|genbank_protein_gi:22547158(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	rogid:skTQJ+iUoHBb06IqVhoprLMYEtA9606	intact-crc:85903BDAC57ED3EE|rigid:mruXzWRckNbqu/b8mpd0DS1yFko	false	sufficient binding region:1-167	sufficient binding region:308-380..380(IPR001440)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O15273	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665206|imex:IM-16425-745	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:85CDF709458C8375|rigid:dNHVLXyVy6FzdaY6IqREqBfdWhQ	false	sufficient binding region:31802-34350(IPR007110)	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15273	uniprotkb:Q8WZ42	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665224|imex:IM-16425-746	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:CEE8A310E34FD68D|rigid:dNHVLXyVy6FzdaY6IqREqBfdWhQ	false	sufficient binding region:1-167	sufficient binding region:30944-34350(IPR002016)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O15273	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665243|imex:IM-16425-747	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N|genbank_protein_gi:19924299(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:CF9D39528B8EFA01|rigid:dNHVLXyVy6FzdaY6IqREqBfdWhQ	false	sufficient binding region:11-34350(IPR003599)	sufficient binding region:1-167	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96S44	uniprotkb:Q14203	intact:EBI-739588|uniprotkb:Q3T977|uniprotkb:Q5JZ01|uniprotkb:Q6NZ60|uniprotkb:Q96FM7|uniprotkb:Q9NQE6|uniprotkb:B3KU44|ensembl:ENSP00000361186	intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300	psi-mi:prpk_human(display_long)|uniprotkb:TP53-regulating kinase(gene name synonym)|uniprotkb:TP53RK(gene name)|psi-mi:TP53RK(display_short)|uniprotkb:C20orf64(gene name synonym)|uniprotkb:PRPK(gene name synonym)|uniprotkb:p53-related protein kinase(gene name synonym)|uniprotkb:Nori-2(gene name synonym)|uniprotkb:Atypical serine/threonine protein kinase TP53RK(gene name synonym)	psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665262|imex:IM-16425-748	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291028.3|ensembl:ENSG00000172315(gene)|ensembl:ENST00000372114(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070525"(tRNA threonylcarbamoyladenosine metabolic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022495|rcsb pdb:6WQX|reactome:R-HSA-6782315|reactome:R-HSA-6804756|genbank_protein_gi:16307276(identity)	refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N|genbank_protein_gi:13259509(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:sgh5tCNgPpL4E4SmEQhLz6qci109606	rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606	intact-crc:0281C9C23A7FFA27|rigid:ztlu+pD3OfGcj9sylBexZkdgWss	false	sufficient binding region:1-253	sufficient binding region:272-1278	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96S44	uniprotkb:Q9BYS8	intact:EBI-739588|uniprotkb:Q3T977|uniprotkb:Q5JZ01|uniprotkb:Q6NZ60|uniprotkb:Q96FM7|uniprotkb:Q9NQE6|uniprotkb:B3KU44|ensembl:ENSP00000361186	intact:EBI-5665279|uniprotkb:Q96LT5|uniprotkb:B2RDQ7|ensembl:ENSP00000296144|ensembl:ENSP00000379241|ensembl:ENSP00000507018	psi-mi:prpk_human(display_long)|uniprotkb:TP53-regulating kinase(gene name synonym)|uniprotkb:TP53RK(gene name)|psi-mi:TP53RK(display_short)|uniprotkb:C20orf64(gene name synonym)|uniprotkb:PRPK(gene name synonym)|uniprotkb:p53-related protein kinase(gene name synonym)|uniprotkb:Nori-2(gene name synonym)|uniprotkb:Atypical serine/threonine protein kinase TP53RK(gene name synonym)	psi-mi:lrrc2_human(display_long)|uniprotkb:LRRC2(gene name)|psi-mi:LRRC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665285|imex:IM-16425-749	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291028.3|ensembl:ENSG00000172315(gene)|ensembl:ENST00000372114(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070525"(tRNA threonylcarbamoyladenosine metabolic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022495|rcsb pdb:6WQX|reactome:R-HSA-6782315|reactome:R-HSA-6804756|genbank_protein_gi:16307276(identity)	refseq:XP_011532412.1|refseq:NP_078788.2|ensembl:ENSG00000163827(gene)|ensembl:ENST00000296144(transcript)|ensembl:ENST00000395905(transcript)|ensembl:ENST00000682605(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|genbank_protein_gi:27545327(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:sgh5tCNgPpL4E4SmEQhLz6qci109606	rogid:Jj3arKY4upKrAAdUsiHfXgvr/GY9606	intact-crc:00F6F079012B171C|rigid:bCHUOoGhRtyyzpvfkGRGR1MveN4	false	sufficient binding region:1-253	sufficient binding region:58-371(IPR003591)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPF4	uniprotkb:Q96S44	intact:EBI-1056510|uniprotkb:Q6IAC3|ensembl:ENSP00000206542	intact:EBI-739588|uniprotkb:Q3T977|uniprotkb:Q5JZ01|uniprotkb:Q6NZ60|uniprotkb:Q96FM7|uniprotkb:Q9NQE6|uniprotkb:B3KU44|ensembl:ENSP00000361186	psi-mi:osgep_human(display_long)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP"(gene name synonym)|uniprotkb:OSGEP(gene name)|psi-mi:OSGEP(display_short)|uniprotkb:GCPL1(gene name synonym)|uniprotkb:O-sialoglycoprotein endopeptidase(gene name synonym)|uniprotkb:tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP(gene name synonym)|uniprotkb:N6-L-threonylcarbamoyladenine synthase(gene name synonym)	psi-mi:prpk_human(display_long)|uniprotkb:TP53-regulating kinase(gene name synonym)|uniprotkb:TP53RK(gene name)|psi-mi:TP53RK(display_short)|uniprotkb:C20orf64(gene name synonym)|uniprotkb:PRPK(gene name synonym)|uniprotkb:p53-related protein kinase(gene name synonym)|uniprotkb:Nori-2(gene name synonym)|uniprotkb:Atypical serine/threonine protein kinase TP53RK(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665303|imex:IM-16425-750	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060277.1|ensembl:ENSG00000092094(gene)|ensembl:ENST00000206542(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0046872"(metal ion binding)|go:"GO:0061711"("N(6)-L-threonylcarbamoyladenine synthase activity")|interpro:IPR000905(Peptidase M22, glycoprotease)|interpro:IPR017860|interpro:IPR017861|interpro:IPR034680|interpro:IPR043129|mint:Q9NPF4|rcsb pdb:6GWJ|reactome:R-HSA-6782315|genbank_protein_gi:50726965(identity)	refseq:NP_291028.3|ensembl:ENSG00000172315(gene)|ensembl:ENST00000372114(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070525"(tRNA threonylcarbamoyladenosine metabolic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022495|rcsb pdb:6WQX|reactome:R-HSA-6782315|reactome:R-HSA-6804756|genbank_protein_gi:16307276(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:gdWaUekKJ7WFXfPlaleW9Dpmsi89606	rogid:sgh5tCNgPpL4E4SmEQhLz6qci109606	intact-crc:CEBD4840D9510DF6|rigid:7x3J72Ei9ndiseSBp3hNfmyE1/I	false	sufficient binding region:93-335..335(IPR000905)	sufficient binding region:1-253	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96S44	uniprotkb:Q8NF91	intact:EBI-739588|uniprotkb:Q3T977|uniprotkb:Q5JZ01|uniprotkb:Q6NZ60|uniprotkb:Q96FM7|uniprotkb:Q9NQE6|uniprotkb:B3KU44|ensembl:ENSP00000361186	intact:EBI-928867|uniprotkb:E7EQI5|uniprotkb:O94890|uniprotkb:Q5JV19|uniprotkb:Q5JV22|uniprotkb:Q8N9P7|uniprotkb:Q8TCP1|uniprotkb:Q8WWW6|uniprotkb:Q8WWW7|uniprotkb:Q8WXF6|uniprotkb:Q96N17|uniprotkb:Q9C0A7|uniprotkb:Q9H525|uniprotkb:Q9H526|uniprotkb:Q9NS36|uniprotkb:Q9NU50|uniprotkb:Q9UJ06|uniprotkb:Q9UJ07|uniprotkb:Q9ULF8|uniprotkb:B3W695|uniprotkb:H0Y4C0|uniprotkb:Q3ZCV0|ensembl:ENSP00000356224	psi-mi:prpk_human(display_long)|uniprotkb:TP53-regulating kinase(gene name synonym)|uniprotkb:TP53RK(gene name)|psi-mi:TP53RK(display_short)|uniprotkb:C20orf64(gene name synonym)|uniprotkb:PRPK(gene name synonym)|uniprotkb:p53-related protein kinase(gene name synonym)|uniprotkb:Nori-2(gene name synonym)|uniprotkb:Atypical serine/threonine protein kinase TP53RK(gene name synonym)	psi-mi:syne1_human(display_long)|uniprotkb:SYNE1(gene name)|psi-mi:SYNE1(display_short)|uniprotkb:KIAA0796(gene name synonym)|uniprotkb:KIAA1262(gene name synonym)|uniprotkb:KIAA1756(gene name synonym)|uniprotkb:MYNE1(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 1(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 1(gene name synonym)|uniprotkb:Myocyte nuclear envelope protein 1(gene name synonym)|uniprotkb:C6orf98(gene name synonym)|uniprotkb:Enaptin(gene name synonym)|uniprotkb:KASH domain-containing protein 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665321|imex:IM-16425-751	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291028.3|ensembl:ENSG00000172315(gene)|ensembl:ENST00000372114(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070525"(tRNA threonylcarbamoyladenosine metabolic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022495|rcsb pdb:6WQX|reactome:R-HSA-6782315|reactome:R-HSA-6804756|genbank_protein_gi:16307276(identity)	refseq:NP_001334631.1|refseq:NP_149062.1|refseq:NP_892006.3|ensembl:ENSG00000131018(gene)|ensembl:ENST00000367255(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006997"(nucleus organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030017"(sarcomere)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR036872|mint:Q8NF91|rcsb pdb:4DXR|rcsb pdb:6R15|rcsb pdb:6XF2|reactome:R-HSA-1221632|genbank_protein_gi:154277115(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:sgh5tCNgPpL4E4SmEQhLz6qci109606	rogid:6nWMBf60nycHwNcMMQJL5JqanEc9606	intact-crc:1FCD2C683EB6D2D2|rigid:iXbqrg9EdxyXm9Hr2QhnHD23dsE	false	sufficient binding region:1-253	sufficient binding region:8117-8797..8797	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96S44	uniprotkb:Q9Y3C4	intact:EBI-739588|uniprotkb:Q3T977|uniprotkb:Q5JZ01|uniprotkb:Q6NZ60|uniprotkb:Q96FM7|uniprotkb:Q9NQE6|uniprotkb:B3KU44|ensembl:ENSP00000361186	intact:EBI-750123|uniprotkb:D6W5H6|uniprotkb:Q8IWR6|uniprotkb:Q8IWR7|uniprotkb:Q9H3K4|ensembl:ENSP00000272424	psi-mi:prpk_human(display_long)|uniprotkb:TP53-regulating kinase(gene name synonym)|uniprotkb:TP53RK(gene name)|psi-mi:TP53RK(display_short)|uniprotkb:C20orf64(gene name synonym)|uniprotkb:PRPK(gene name synonym)|uniprotkb:p53-related protein kinase(gene name synonym)|uniprotkb:Nori-2(gene name synonym)|uniprotkb:Atypical serine/threonine protein kinase TP53RK(gene name synonym)	psi-mi:tprkb_human(display_long)|uniprotkb:PRPK-binding protein(gene name synonym)|uniprotkb:TPRKB(gene name)|psi-mi:TPRKB(display_short)|uniprotkb:TP53RK-binding protein(gene name synonym)|uniprotkb:CGI-121(orf name)|uniprotkb:My019(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665338|imex:IM-16425-752	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291028.3|ensembl:ENSG00000172315(gene)|ensembl:ENST00000372114(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070525"(tRNA threonylcarbamoyladenosine metabolic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022495|rcsb pdb:6WQX|reactome:R-HSA-6782315|reactome:R-HSA-6804756|genbank_protein_gi:16307276(identity)	refseq:XP_011531179.1|refseq:XP_011531180.1|refseq:NP_057142.1|refseq:XP_006712090.1|refseq:NP_001317315.1|refseq:NP_001317316.1|refseq:NP_001317317.1|refseq:NP_001317318.1|refseq:NP_001317320.1|refseq:NP_001317321.1|refseq:XP_016859721.1|refseq:XP_016859722.1|refseq:XP_016859723.1|ensembl:ENSG00000144034(gene)|ensembl:ENST00000272424(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR013926(Kinase binding protein CGI-121)|interpro:IPR036504|rcsb pdb:3ENP|rcsb pdb:6WQX|reactome:R-HSA-6782315|genbank_protein_gi:7705589(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:sgh5tCNgPpL4E4SmEQhLz6qci109606	rogid:hsboCuMYBT3FzLom262TDGm5lOQ9606	intact-crc:4948B5D97F457C3B|rigid:zVb5uHwiaN8dMyUs+1tTnT2h/2I	false	sufficient binding region:1-253	sufficient binding region:1-175..175	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N0Z2	uniprotkb:P0DI81	intact:EBI-3893380|ensembl:ENSP00000311436	intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155	psi-mi:abra_human(display_long)|uniprotkb:ABRA(gene name)|psi-mi:ABRA(display_short)|uniprotkb:Striated muscle activator of Rho-dependent signaling(gene name synonym)	psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665355|imex:IM-16425-753	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_631905.1|ensembl:ENSG00000174429(gene)|ensembl:ENST00000311955(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|interpro:IPR026111|interpro:IPR027817|interpro:IPR038095|genbank_protein_gi:31543660(identity)	refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198|genbank_protein_gi:30851693(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:2ULGI3cUL9LZQTvgeB27BIL/tyU9606	rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606	intact-crc:0F23DAA7EC28B4BC|rigid:3zufgRYQpEFJpfsxUwrmvui7ueM	false	sufficient binding region:192-381	sufficient binding region:1-140	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99613	uniprotkb:P0DI81	intact:EBI-353741|uniprotkb:A8K7Z0|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-11017021|ensembl:ENSP00000332604|ensembl:ENSP00000378953|ensembl:ENSP00000457418|ensembl:ENSP00000457963|uniprotkb:B4E1D5|uniprotkb:H3BRV0	intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155	psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)	psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665372|imex:IM-16425-754	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|refseq:NP_001273407.1|ensembl:ENSG00000184110(gene)|ensembl:ENST00000331666(transcript)|ensembl:ENST00000395587(transcript)|ensembl:ENST00000566501(transcript)|ensembl:ENST00000566866(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001254503.1|dip:DIP-32865N|genbank_protein_gi:83700232(identity)	refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198|genbank_protein_gi:30851693(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606	rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606	intact-crc:F4C657EC4C750620|rigid:NCAxnQQMC2cKy53W1hcf7+p+ZKQ	false	sufficient binding region:752-913(IPR000717)	sufficient binding region:1-140	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0DI81	uniprotkb:P06733	intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665390|imex:IM-16425-755	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198|genbank_protein_gi:30851693(identity)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_protein_gi:16507965(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:EDE87FBD0AE354FC|rigid:lf3Froh26zj5ZsVv8TbJTsWYICM	false	sufficient binding region:1-140	sufficient binding region:69-434(IPR000941)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13929	uniprotkb:P0DI81	intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087	intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155	psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)	psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665408|imex:IM-16425-756	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|genbank_protein_gi:33878987(identity)	refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198|genbank_protein_gi:30851693(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606	rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606	intact-crc:9C5CB02D2CE5563A|rigid:/HBb+i5ww9SMrzbXn1DgfUx2EUg	false	sufficient binding region:112-434(IPR000941)	sufficient binding region:1-140	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13747	uniprotkb:P0DI81	intact:EBI-726583|uniprotkb:Q30169|uniprotkb:Q9BT83|uniprotkb:Q9GIY7|uniprotkb:Q9GIY8|ensembl:ENSP00000365817|ensembl:ENSP00000373091|ensembl:ENSP00000390707|ensembl:ENSP00000397420|ensembl:ENSP00000400458|ensembl:ENSP00000402694|ensembl:ENSP00000409910|uniprotkb:E2G051|uniprotkb:Q6DU44	intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155	psi-mi:hlae_human(display_long)|uniprotkb:MHC class I antigen E(gene name synonym)|uniprotkb:HLA-E(gene name)|psi-mi:HLA-E(display_short)|uniprotkb:HLA-6.2(gene name synonym)|uniprotkb:HLAE(gene name synonym)	psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665426|imex:IM-16425-757	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005507.3|ensembl:ENSG00000204592(gene)|ensembl:ENSG00000206493(gene)|ensembl:ENSG00000225201(gene)|ensembl:ENSG00000229252(gene)|ensembl:ENSG00000230254(gene)|ensembl:ENSG00000233904(gene)|ensembl:ENSG00000236632(gene)|ensembl:ENST00000376630(transcript)|ensembl:ENST00000383597(transcript)|ensembl:ENST00000415289(transcript)|ensembl:ENST00000415649(transcript)|ensembl:ENST00000425603(transcript)|ensembl:ENST00000427936(transcript)|ensembl:ENST00000444683(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001815"(positive regulation of antibody-dependent cellular cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0002477"(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:"GO:0002519"(natural killer cell tolerance induction)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002715"(regulation of natural killer cell mediated immunity)|go:"GO:0002717"(positive regulation of natural killer cell mediated immunity)|go:"GO:0002729"(positive regulation of natural killer cell cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032398"(MHC class Ib protein complex)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032759"(positive regulation of TRAIL production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032819"(positive regulation of natural killer cell proliferation)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1MHE|rcsb pdb:2ESV|rcsb pdb:3AM8|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2001187"(positive regulation of CD8-positive, alpha-beta T cell activation)|rcsb pdb:6GHN|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|rcsb pdb:6GL1|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|dip:DIP-32N|genbank_protein_gi:34783126(identity)	refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198|genbank_protein_gi:30851693(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2019/01/23	rogid:JhlO0lcqZm7whCQasHSnQdrA5Tk9606	rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606	intact-crc:AFBF332F5A1ED63A|rigid:Y2rmXNCYbWUnyE4lUcal64eHmvQ	false	sufficient binding region:313-358..358	sufficient binding region:1-140	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11217	uniprotkb:P0DI81	intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139	intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155	psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665443|imex:IM-16425-758	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|genbank_protein_gi:5032008(identity)	refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198|genbank_protein_gi:30851693(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606	rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606	intact-crc:B5E157060BCF5645|rigid:33F/IjQYdXyX9EsT+vuI3DPg518	false	sufficient binding region:607-842	sufficient binding region:1-140	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0DI81	uniprotkb:Q8NAP3	intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155	intact:EBI-5235984|uniprotkb:D3DNF6|intact:EBI-28968990|ensembl:ENSP00000372635|ensembl:ENSP00000406955|ensembl:ENSP00000426387|ensembl:ENSP00000490041	psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short)	psi-mi:zbt38_human(display_long)|uniprotkb:ZBTB38(gene name)|psi-mi:ZBTB38(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665460|imex:IM-16425-759	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198|genbank_protein_gi:30851693(identity)	ensembl:ENSP00000372635|ensembl:ENSP00000406955|ensembl:ENSP00000426387|ensembl:ENSP00000490041|refseq:XP_011510913.1|refseq:XP_005247314.1|refseq:XP_005247315.1|refseq:NP_001073881.2|refseq:XP_005247318.1|refseq:XP_016861541.1|refseq:XP_016861542.1|refseq:XP_016861543.1|refseq:XP_016861544.1|refseq:XP_016861545.1|refseq:XP_016861546.1|refseq:XP_016861547.1|refseq:XP_016861548.1|refseq:XP_016861549.1|refseq:XP_016861550.1|ensembl:ENSG00000177311(gene)|ensembl:ENST00000321464(transcript)|ensembl:ENST00000441582(transcript)|ensembl:ENST00000514251(transcript)|ensembl:ENST00000637056(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8NAP3|rcsb pdb:6E93|rcsb pdb:6E94|genbank_protein_gi:122937220(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606	rogid:2hYBmm9S5uBZPL4JBUvGWQaTPak9606	intact-crc:E5C62C65B67A1054|rigid:BqI5YLrHKaxYYVF4FJpXv5Nc3Ug	false	sufficient binding region:1-140	sufficient binding region:438-1195	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8T0	uniprotkb:Q13049	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665477|imex:IM-16425-760	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|genbank_protein_gi:33876026(identity)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1|genbank_protein_gi:758422(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	intact-crc:97C3A4AE36009D65|rigid:aGBe460HpJU4dyzuCUMzy6jR8CE	false	sufficient binding region:64-292(IPR000608)	sufficient binding region:66-653	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P24043	uniprotkb:Q969Q1	intact:EBI-2529730|uniprotkb:Q14736|uniprotkb:Q5VUM2|uniprotkb:Q93022|ensembl:ENSP00000400365	intact:EBI-5661333|uniprotkb:Q9BYV4|uniprotkb:Q96BD3|uniprotkb:Q96KD9|uniprotkb:Q5T2I1|uniprotkb:B4DN95|ensembl:ENSP00000363390	psi-mi:lama2_human(display_long)|uniprotkb:Laminin-2 subunit alpha(gene name synonym)|uniprotkb:Laminin-4 subunit alpha(gene name synonym)|uniprotkb:Laminin-12 subunit alpha(gene name synonym)|uniprotkb:LAMA2(gene name)|psi-mi:LAMA2(display_short)|uniprotkb:LAMM(gene name synonym)|uniprotkb:Laminin M chain(gene name synonym)|uniprotkb:Merosin heavy chain(gene name synonym)	psi-mi:tri63_human(display_long)|uniprotkb:IRF(gene name synonym)|uniprotkb:Iris RING finger protein(gene name synonym)|uniprotkb:MURF1(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 28(gene name synonym)|uniprotkb:RNF28(gene name synonym)|uniprotkb:SMRZ(gene name synonym)|uniprotkb:Striated muscle RING zinc finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 63(gene name synonym)|uniprotkb:TRIM63(gene name)|psi-mi:TRIM63(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM63(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665495|imex:IM-16425-761	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000196569(gene)|ensembl:ENST00000421865(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042383"(sarcolemma)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043197"(dendritic spine)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|mint:P24043|rcsb pdb:4YEP|rcsb pdb:4YEQ|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-8874081|reactome:R-HSA-9619665|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_000417.2|refseq:NP_001073291.1|dip:DIP-42562N|genbank_protein_gi:119466531(identity)	refseq:NP_115977.2|ensembl:ENSG00000158022(gene)|ensembl:ENST00000374272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR042667|mint:Q969Q1|rcsb pdb:2D8U|rcsb pdb:3DDT|rcsb pdb:4M3L|reactome:R-HSA-9615017|reactome:R-HSA-983168|genbank_protein_gi:19924162(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:z2F+5o5SCklBK+JoJkvTFZlOgNc9606	rogid:fxaNyoTJdzJyjJb+QYEZ+d72DbA9606	intact-crc:F23731076370BB61|rigid:BWnTE3Lf8ncoLWhCuh9ciruZo08	false	sufficient binding region:1191-3122	sufficient binding region:1-353	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV2	uniprotkb:Q969Q1	intact:EBI-2130429|uniprotkb:A5D8T7|uniprotkb:Q53SY4|uniprotkb:Q9BYV3|ensembl:ENSP00000369415	intact:EBI-5661333|uniprotkb:Q9BYV4|uniprotkb:Q96BD3|uniprotkb:Q96KD9|uniprotkb:Q5T2I1|uniprotkb:B4DN95|ensembl:ENSP00000363390	psi-mi:tri54_human(display_long)|uniprotkb:TRIM54(gene name)|psi-mi:TRIM54(display_short)|uniprotkb:MURF(gene name synonym)|uniprotkb:MURF3(gene name synonym)|uniprotkb:RNF30(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 3(gene name synonym)|uniprotkb:Muscle-specific RING finger protein(gene name synonym)|uniprotkb:RING finger protein 30(gene name synonym)	psi-mi:tri63_human(display_long)|uniprotkb:IRF(gene name synonym)|uniprotkb:Iris RING finger protein(gene name synonym)|uniprotkb:MURF1(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 28(gene name synonym)|uniprotkb:RNF28(gene name synonym)|uniprotkb:SMRZ(gene name synonym)|uniprotkb:Striated muscle RING zinc finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 63(gene name synonym)|uniprotkb:TRIM63(gene name)|psi-mi:TRIM63(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM63(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665512|imex:IM-16425-762	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115935.3|refseq:NP_912730.2|interpro:IPR027370|interpro:IPR033492|interpro:IPR042752|rcsb pdb:3Q1D|ensembl:ENSG00000138100(gene)|ensembl:ENST00000380075(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|genbank_protein_gi:34878869(identity)	refseq:NP_115977.2|ensembl:ENSG00000158022(gene)|ensembl:ENST00000374272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR042667|mint:Q969Q1|rcsb pdb:2D8U|rcsb pdb:3DDT|rcsb pdb:4M3L|reactome:R-HSA-9615017|reactome:R-HSA-983168|genbank_protein_gi:19924162(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:rxNKa4ddkMuN1HQlCnhYo2Ypi589606	rogid:fxaNyoTJdzJyjJb+QYEZ+d72DbA9606	intact-crc:3782D140300DE2C1|rigid:KEeJK8/ObTj71azQNm0FndUbzW4	false	sufficient binding region:1-358	sufficient binding region:1-353	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV6	uniprotkb:Q969Q1	intact:EBI-2341179|uniprotkb:Q96DV3|uniprotkb:Q9BYV5|uniprotkb:Q8IUD9|uniprotkb:Q8IUE4|uniprotkb:Q96DV2|uniprotkb:Q53XX3|uniprotkb:B3KRC0|uniprotkb:B3KRJ3|ensembl:ENSP00000323913	intact:EBI-5661333|uniprotkb:Q9BYV4|uniprotkb:Q96BD3|uniprotkb:Q96KD9|uniprotkb:Q5T2I1|uniprotkb:B4DN95|ensembl:ENSP00000363390	psi-mi:tri55_human(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)	psi-mi:tri63_human(display_long)|uniprotkb:IRF(gene name synonym)|uniprotkb:Iris RING finger protein(gene name synonym)|uniprotkb:MURF1(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 28(gene name synonym)|uniprotkb:RNF28(gene name synonym)|uniprotkb:SMRZ(gene name synonym)|uniprotkb:Striated muscle RING zinc finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 63(gene name synonym)|uniprotkb:TRIM63(gene name)|psi-mi:TRIM63(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM63(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665529|imex:IM-16425-763	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011515915.1|refseq:XP_011515916.1|refseq:XP_011515917.1|refseq:XP_011515918.1|refseq:NP_149047.2|refseq:NP_908973.1|refseq:NP_908974.1|refseq:NP_908975.1|ensembl:ENSG00000147573(gene)|ensembl:ENST00000315962(transcript)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0050904"(diapedesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1905517"(macrophage migration)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR033492|mint:Q9BYV6|genbank_protein_gi:34878843(identity)	refseq:NP_115977.2|ensembl:ENSG00000158022(gene)|ensembl:ENST00000374272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR042667|mint:Q969Q1|rcsb pdb:2D8U|rcsb pdb:3DDT|rcsb pdb:4M3L|reactome:R-HSA-9615017|reactome:R-HSA-983168|genbank_protein_gi:19924162(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:MiXH7mPPLOjav9yf0/HL7neg3yI9606	rogid:fxaNyoTJdzJyjJb+QYEZ+d72DbA9606	intact-crc:31414B00411A3A70|rigid:HIr2U5vb5C9C+HqO3hGTL3/arxM	false	sufficient binding region:160-548	sufficient binding region:1-353	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969Q1	uniprotkb:Q969Q1	intact:EBI-5661333|uniprotkb:Q9BYV4|uniprotkb:Q96BD3|uniprotkb:Q96KD9|uniprotkb:Q5T2I1|uniprotkb:B4DN95|ensembl:ENSP00000363390	intact:EBI-5661333|uniprotkb:Q9BYV4|uniprotkb:Q96BD3|uniprotkb:Q96KD9|uniprotkb:Q5T2I1|uniprotkb:B4DN95|ensembl:ENSP00000363390	psi-mi:tri63_human(display_long)|uniprotkb:IRF(gene name synonym)|uniprotkb:Iris RING finger protein(gene name synonym)|uniprotkb:MURF1(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 28(gene name synonym)|uniprotkb:RNF28(gene name synonym)|uniprotkb:SMRZ(gene name synonym)|uniprotkb:Striated muscle RING zinc finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 63(gene name synonym)|uniprotkb:TRIM63(gene name)|psi-mi:TRIM63(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM63(gene name synonym)	psi-mi:tri63_human(display_long)|uniprotkb:IRF(gene name synonym)|uniprotkb:Iris RING finger protein(gene name synonym)|uniprotkb:MURF1(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 28(gene name synonym)|uniprotkb:RNF28(gene name synonym)|uniprotkb:SMRZ(gene name synonym)|uniprotkb:Striated muscle RING zinc finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 63(gene name synonym)|uniprotkb:TRIM63(gene name)|psi-mi:TRIM63(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM63(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665546|imex:IM-16425-764	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115977.2|ensembl:ENSG00000158022(gene)|ensembl:ENST00000374272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR042667|mint:Q969Q1|rcsb pdb:2D8U|rcsb pdb:3DDT|rcsb pdb:4M3L|reactome:R-HSA-9615017|reactome:R-HSA-983168|genbank_protein_gi:19924162(identity)	refseq:NP_115977.2|ensembl:ENSG00000158022(gene)|ensembl:ENST00000374272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR042667|mint:Q969Q1|rcsb pdb:2D8U|rcsb pdb:3DDT|rcsb pdb:4M3L|reactome:R-HSA-9615017|reactome:R-HSA-983168|genbank_protein_gi:19924162(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:fxaNyoTJdzJyjJb+QYEZ+d72DbA9606	rogid:fxaNyoTJdzJyjJb+QYEZ+d72DbA9606	intact-crc:17E130351C9CE93F|rigid:Em+6Do7aT8c3LdTxqp680iT6gmw	false	sufficient binding region:1-353	sufficient binding region:215-353	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q969Q1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5661333|uniprotkb:Q9BYV4|uniprotkb:Q96BD3|uniprotkb:Q96KD9|uniprotkb:Q5T2I1|uniprotkb:B4DN95|ensembl:ENSP00000363390	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:tri63_human(display_long)|uniprotkb:IRF(gene name synonym)|uniprotkb:Iris RING finger protein(gene name synonym)|uniprotkb:MURF1(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 28(gene name synonym)|uniprotkb:RNF28(gene name synonym)|uniprotkb:SMRZ(gene name synonym)|uniprotkb:Striated muscle RING zinc finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 63(gene name synonym)|uniprotkb:TRIM63(gene name)|psi-mi:TRIM63(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM63(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665563|imex:IM-16425-765	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_115977.2|ensembl:ENSG00000158022(gene)|ensembl:ENST00000374272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR042667|mint:Q969Q1|rcsb pdb:2D8U|rcsb pdb:3DDT|rcsb pdb:4M3L|reactome:R-HSA-9615017|reactome:R-HSA-983168|genbank_protein_gi:19924162(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:fxaNyoTJdzJyjJb+QYEZ+d72DbA9606	intact-crc:030F457386A2495A|rigid:oYCI8n0u8aO/UnOCR9syJOnVdGw	false	sufficient binding region:30988-34350(IPR002016)	sufficient binding region:1-353	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14639	uniprotkb:Q8WZ42	intact:EBI-487024|uniprotkb:A6NI16|uniprotkb:Q5T6N3|uniprotkb:Q5JVV1|uniprotkb:Q15039|uniprotkb:Q68CQ9|uniprotkb:Q9BUP1|uniprotkb:Q5T6N5|uniprotkb:B3KVH2|uniprotkb:Q5T6N2|uniprotkb:A6NJ06|uniprotkb:A8MXA9|uniprotkb:Q5JVV2|ensembl:ENSP00000277895	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:ablm1_human(display_long)|uniprotkb:Actin-binding LIM protein family member 1(gene name synonym)|uniprotkb:Actin-binding double zinc finger protein(gene name synonym)|uniprotkb:Limatin(gene name synonym)|uniprotkb:ABLIM1(gene name)|psi-mi:ABLIM1(display_short)|uniprotkb:ABLIM(gene name synonym)|uniprotkb:KIAA0059(gene name synonym)|uniprotkb:LIMAB1(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665582|imex:IM-16425-766	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003407.1|refseq:NP_002304.3|refseq:NP_006711.3|ensembl:ENSG00000099204(gene)|ensembl:ENST00000277895(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003128(Villin headpiece)|interpro:IPR028448|interpro:IPR032402|interpro:IPR036886|mint:O14639|reactome:R-HSA-418885|go:"GO:0030032"(lamellipodium assembly)|refseq:NP_001309811.1|refseq:NP_001309821.1|refseq:NP_001309822.1|refseq:NP_001309825.1|genbank_protein_gi:51173714(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Dsx3GrmdlsYUmQvuW59NfYF7MJg9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:B471E166940B7F66|rigid:z2XgZwh4TqvR/acEpUrWO+k3f1s	false	sufficient binding region:76-778	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q6H8Q1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2826517|ensembl:ENSP00000342813|intact:EBI-3451222|uniprotkb:Q08E71|uniprotkb:Q19VH0|uniprotkb:Q6H8Q0|uniprotkb:Q6NX73|uniprotkb:Q8N3C5|uniprotkb:Q8N9E9|uniprotkb:Q8N9G2|uniprotkb:Q96JL7|uniprotkb:E9PF39	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:ablm2_human(display_long)|uniprotkb:ABLIM2(gene name)|psi-mi:ABLIM2(display_short)|uniprotkb:Actin-binding LIM protein family member 2(gene name synonym)|uniprotkb:KIAA1808(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665599|imex:IM-16425-767	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001123558.1|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003128(Villin headpiece)|interpro:IPR028450|interpro:IPR032402|interpro:IPR036886|rcsb pdb:1V6G|rcsb pdb:1WIG|rcsb pdb:2L3X|reactome:R-HSA-418885|ensembl:ENSG00000163995(gene)|ensembl:ENST00000341937(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001273617.1|refseq:NP_001123555.1|refseq:NP_001123556.1|refseq:NP_001123557.1|refseq:NP_001123559.1|refseq:NP_001123560.1|refseq:NP_115808.3|genbank_protein_gi:40316949(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:eEvWoQSviWU/EaFD8wg23VsVglM9606	intact-crc:844435949724AD4C|rigid:1y0ovIRWPvbCTaixhhfttYb+PRU	false	sufficient binding region:29808-30118	sufficient binding region:104-611	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35609	uniprotkb:Q8WZ42	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665616|imex:IM-16425-768	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:63643E7CB29143DC|rigid:RfFwXwxlV+S6NZBkR/36DpaoL0A	false	sufficient binding region:404-894(IPR002017)	sufficient binding region:741-948	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35609	uniprotkb:Q8WZ42	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665634|imex:IM-16425-769	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:7DACB825CBF2C42D|rigid:RfFwXwxlV+S6NZBkR/36DpaoL0A	false	sufficient binding region:830-894..894(IPR002017)	sufficient binding region:97-469	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q08043	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2880652|ensembl:ENSP00000426797|uniprotkb:Q4KKV2|uniprotkb:A6NP77	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:actn3_human(display_long)|uniprotkb:ACTN3(gene name)|psi-mi:ACTN3(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 3(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665652|imex:IM-16425-770	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051015"(actin filament binding)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904025"(positive regulation of glucose catabolic process to lactate via pyruvate)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|ensembl:ENSG00000248746(gene)|ensembl:ENST00000513398(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0030018"(Z disc)|go:"GO:0031143"(pseudopodium)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0042802"(identical protein binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1TJT|rcsb pdb:1WKU|rcsb pdb:3LUE|reactome:R-HSA-373753|reactome:R-HSA-390522|refseq:NP_001245300.2|refseq:NP_001095.2|genbank_protein_gi:4557240(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:ihTlyeKGYaTOZTmd5oP5FeFmo089606	intact-crc:85DC2CFE777002A1|rigid:nu+1b1oGidhRrUMwijLL/YfqWQg	false	sufficient binding region:97-469	sufficient binding region:831-901..901(IPR000634)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43707	uniprotkb:Q8WZ42	intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|ensembl:ENSP00000252699|ensembl:ENSP00000489220|uniprotkb:A4K467	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665670|imex:IM-16425-771	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004915.2|ensembl:ENSG00000130402(gene)|ensembl:ENSG00000282844(gene)|ensembl:ENST00000252699(transcript)|ensembl:ENST00000634960(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|dip:DIP-33179N|genbank_protein_gi:34452697(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:ECA33F7AAE00290E|rigid:YN/dc+Wr6eK48G3SioMTCo3gkZA	false	sufficient binding region:821-911..911(IPR002048)	sufficient binding region:97-469	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30049	uniprotkb:Q8WZ42	intact:EBI-1049505|uniprotkb:Q6FG90|uniprotkb:D6W5Y3|ensembl:ENSP00000215375|ensembl:ENSP00000378995|ensembl:ENSP00000464863	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:atpd_human(display_long)|uniprotkb:ATP5F1D(gene name)|psi-mi:ATP5F1D(display_short)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:ATP5D(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665688|imex:IM-16425-772	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001975.1|refseq:NP_001678.1|ensembl:ENSG00000099624(gene)|ensembl:ENST00000215375(transcript)|ensembl:ENST00000395633(transcript)|ensembl:ENST00000591660(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046688"(response to copper ion)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|interpro:IPR036794|mint:P30049|reactome:R-HSA-163210|reactome:R-HSA-8949613|genbank_protein_gi:50345990(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:OA8if7wpjwV6hkkaLqPyz6YDljc9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:9C34B5655937C452|rigid:iRiPDAmKHHsX7YoyNAxS49ffLvM	false	sufficient binding region:43-168..168	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14839	uniprotkb:Q8WZ42	intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665705|imex:IM-16425-773	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N|genbank_protein_gi:51599155(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:8F2B8B48D35A23C5|rigid:IcY3dFDFZiFbHay4icdRsqLzg8k	false	sufficient binding region:698-1912	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14839	uniprotkb:Q8WZ42	intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665722|imex:IM-16425-774	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N|genbank_protein_gi:51599155(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:5BFF88815359345A|rigid:IcY3dFDFZiFbHay4icdRsqLzg8k	false	sufficient binding region:698-1912	sufficient binding region:2120-2564	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:O75953	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665739|imex:IM-16425-775	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|genbank_protein_gi:56549114(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	intact-crc:58D97E263D77844A|rigid:k49fvi5XwA9rd0dPwsQosxEA8Rw	false	sufficient binding region:8831-9158	sufficient binding region:172-348	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q01780	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665756|imex:IM-16425-776	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|genbank_protein_gi:50301239(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:CD2AF7048106A053|rigid:bNsvAQrxJ+jzooZ8Qs31Iy3Wmh4	false	sufficient binding region:2120-2564	sufficient binding region:568-885	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13642	uniprotkb:Q8WZ42	intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665773|imex:IM-16425-777	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ|genbank_protein_gi:34147646(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:C19F7086D4E2726E|rigid:ZQ+17or+HVTisDt6CLk3hshIAMk	false	sufficient binding region:36-323	sufficient binding region:8831-9158	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P02751	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665790|imex:IM-16425-778	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|genbank_protein_gi:47132548(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2019/10/18	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:249A49680FC40CF6|rigid:yENf2nJjnufT943c0Vuej5AZyS0	false	sufficient binding region:29808-30118	sufficient binding region:1864-2477(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53EP0	uniprotkb:Q8WZ42	intact:EBI-2847708|uniprotkb:Q6PIJ3|uniprotkb:B2RB36|uniprotkb:Q8NBU7|uniprotkb:Q6UXG1|uniprotkb:B3KXR8|uniprotkb:Q5U5T8|uniprotkb:Q9H5I7|uniprotkb:Q8IXB2|uniprotkb:Q9NSQ8|uniprotkb:Q96D78|uniprotkb:Q6UXZ5|uniprotkb:D3DNQ7|ensembl:ENSP00000338523|ensembl:ENSP00000389094|ensembl:ENSP00000411242	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:fnd3b_human(display_long)|uniprotkb:FNDC3B(gene name)|psi-mi:FNDC3B(display_short)|uniprotkb:FAD104(gene name synonym)|uniprotkb:NS5ABP37(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 104(gene name synonym)|uniprotkb:HCV NS5A-binding protein 37(gene name synonym)|uniprotkb:UNQ2421/PRO4979/PRO34274(orf name)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665808|imex:IM-16425-779	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128567.1|refseq:NP_073600.3|ensembl:ENSP00000338523|ensembl:ENSP00000411242|ensembl:ENSP00000389094|ensembl:ENST00000421757|ensembl:ENSP00000408496|ensembl:ENST00000423424|ensembl:ENSP00000392471|ensembl:ENSG00000075420(gene)|ensembl:ENST00000336824(transcript)|ensembl:ENST00000415807(transcript)|ensembl:ENST00000416957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:Q53EP0|genbank_protein_gi:27477058(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:a8Yk/79adiuueOBYtKZSPnN71u09606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:1C9F3A279F2132CE|rigid:6wREJW/aHKaR62338wiQmg7n670	false	sufficient binding region:904-1204(IPR003961)	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q53EP0	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-2847708|uniprotkb:Q6PIJ3|uniprotkb:B2RB36|uniprotkb:Q8NBU7|uniprotkb:Q6UXG1|uniprotkb:B3KXR8|uniprotkb:Q5U5T8|uniprotkb:Q9H5I7|uniprotkb:Q8IXB2|uniprotkb:Q9NSQ8|uniprotkb:Q96D78|uniprotkb:Q6UXZ5|uniprotkb:D3DNQ7|ensembl:ENSP00000338523|ensembl:ENSP00000389094|ensembl:ENSP00000411242	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:fnd3b_human(display_long)|uniprotkb:FNDC3B(gene name)|psi-mi:FNDC3B(display_short)|uniprotkb:FAD104(gene name synonym)|uniprotkb:NS5ABP37(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 104(gene name synonym)|uniprotkb:HCV NS5A-binding protein 37(gene name synonym)|uniprotkb:UNQ2421/PRO4979/PRO34274(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665826|imex:IM-16425-780	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001128567.1|refseq:NP_073600.3|ensembl:ENSP00000338523|ensembl:ENSP00000411242|ensembl:ENSP00000389094|ensembl:ENST00000421757|ensembl:ENSP00000408496|ensembl:ENST00000423424|ensembl:ENSP00000392471|ensembl:ENSG00000075420(gene)|ensembl:ENST00000336824(transcript)|ensembl:ENST00000415807(transcript)|ensembl:ENST00000416957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:Q53EP0|genbank_protein_gi:27477058(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:a8Yk/79adiuueOBYtKZSPnN71u09606	intact-crc:289D74272EE5DBEA|rigid:6wREJW/aHKaR62338wiQmg7n670	false	sufficient binding region:29808-30118	sufficient binding region:724-1204(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95166	uniprotkb:Q8WZ42	intact:EBI-712001|ensembl:ENSP00000306866	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:gbrap_human(display_long)|uniprotkb:"GABA(A) receptor-associated protein"(gene name synonym)|uniprotkb:MM46(gene name synonym)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:FLC3B(gene name synonym)|uniprotkb:HT004(orf name)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665844|imex:IM-16425-781	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000170296(gene)|ensembl:ENST00000302386(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006605"(protein targeting)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008017"(microtubule binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:O95166|rcsb pdb:1GNU|rcsb pdb:1KLV|rcsb pdb:1KM7|rcsb pdb:1KOT|rcsb pdb:3D32|rcsb pdb:3DOW|rcsb pdb:3WIM|rcsb pdb:4XC2|rcsb pdb:5DPS|rcsb pdb:6HB9|rcsb pdb:6HOG|rcsb pdb:6HOH|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:6HYL|rcsb pdb:6HYN|rcsb pdb:6HYO|rcsb pdb:6YOP|rcsb pdb:7AA8|rcsb pdb:7BRQ|rcsb pdb:7BRT|rcsb pdb:7BRU|rcsb pdb:7BV4|reactome:R-HSA-1632852|reactome:R-HSA-8854214|rcsb pdb:6HYM|refseq:NP_009209.1|dip:DIP-35050N|genbank_protein_gi:6005763(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PRC57VUrKgXozj1jnvgz7MQERK09606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:EA454E7919D8D21F|rigid:vOrf0fU/sF002oikgS+sF5ihRPw	false	sufficient binding region:30-117..117	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P08107	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665861|imex:IM-16425-782	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|genbank_protein_gi:39645781(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:DE10CA63686F96AE|rigid:DEflL7lYSGPEbyoSixcPWB/iBCk	false	sufficient binding region:2120-2564	sufficient binding region:374-641(IPR001023)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HDC5	uniprotkb:Q8WZ42	intact:EBI-465137|ensembl:ENSP00000344488|uniprotkb:B2RTZ0	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665879|imex:IM-16425-783	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104369(gene)|ensembl:ENST00000342232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060402"(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|refseq:NP_065698.1|refseq:NP_001304759.1|refseq:XP_005251331.1|refseq:XP_005251332.1|genbank_protein_gi:61676191(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:B0058AA9F4C8D005|rigid:Sc1T9DNrFLw6K+16tcXx63mwj1w	false	sufficient binding region:270-661(IPR003409)	sufficient binding region:8831-9158	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P0Q8	uniprotkb:Q8WZ42	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665897|imex:IM-16425-784	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|genbank_protein_gi:41350924(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:6F9C37165FD9EA12|rigid:4cemqk1d/L2DWjot4qq4gdcShPM	false	sufficient binding region:457-1798	sufficient binding region:32840-33423	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q00872	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5652924|uniprotkb:B4DKR5|uniprotkb:B7Z8G8|uniprotkb:B7ZL02|uniprotkb:B7ZL09|uniprotkb:B7ZL10|uniprotkb:E7ESM5|uniprotkb:E7EWS6|uniprotkb:Q17RR7|uniprotkb:Q8N3L2|uniprotkb:Q569K7|uniprotkb:Q15497|uniprotkb:G3XAE8|uniprotkb:Q86T48|uniprotkb:Q86TC8|ensembl:ENSP00000449702	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:mypc1_human(display_long)|uniprotkb:C-protein, skeletal muscle slow isoform(gene name synonym)|uniprotkb:MYBPCS(gene name synonym)|uniprotkb:MYBPC1(gene name)|psi-mi:MYBPC1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665914|imex:IM-16425-785	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_996556.1|refseq:NP_996557.1|refseq:NP_002456.2|refseq:NP_001241647.1|refseq:NP_001241648.1|refseq:NP_001241649.1|refseq:NP_001241650.1|refseq:NP_001241651.1|refseq:NP_001241652.1|refseq:NP_996555.1|ensembl:ENSG00000196091(gene)|ensembl:ENST00000550270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0031432"(titin binding)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|rcsb pdb:1X44|rcsb pdb:2DAV|rcsb pdb:2YUV|rcsb pdb:2YUW|rcsb pdb:2YUX|rcsb pdb:2YUZ|rcsb pdb:2YXM|reactome:R-HSA-390522|genbank_protein_gi:46049118(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:0d3aCksN/udqtna8xZ2cJ3UcHxw9606	intact-crc:B505D0E84EFA2A54|rigid:LqDu3+koAw+MgqHhlvRu+K2LRKw	false	sufficient binding region:2120-2564	sufficient binding region:370-1141(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q14324	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665933|imex:IM-16425-786	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	intact-crc:AA2AE93D2BB2B105|rigid:LLznsFDCo6Sr8lo5EVWJFHefFbU	false	sufficient binding region:29808-30118	sufficient binding region:770-1141(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75592	uniprotkb:Q8WZ42	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665952|imex:IM-16425-787	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055872.4|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003646(Bacterial SH3-like region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|ensembl:ENSG00000005810(gene)|ensembl:ENST00000544440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|dip:DIP-28142N|genbank_protein_gi:126116564(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/07/05	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:B49C35C6B3EBA3EB|rigid:StG97a+bTnTt3AB+jGXaTeAUcik	false	sufficient binding region:2527-4678	sufficient binding region:741-948	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52179	uniprotkb:Q8WZ42	intact:EBI-5353249|uniprotkb:Q14BD6|uniprotkb:Q6H969|uniprotkb:Q6ZUU0|ensembl:ENSP00000348821	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:myom1_human(display_long)|uniprotkb:MYOM1(gene name)|psi-mi:MYOM1(display_short)|uniprotkb:190 kDa connectin-associated protein(gene name synonym)|uniprotkb:190 kDa titin-associated protein(gene name synonym)|uniprotkb:Myomesin family member 1(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665969|imex:IM-16425-788	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59649N|refseq:NP_003794.3|refseq:NP_062830.1|ensembl:ENSG00000101605(gene)|ensembl:ENST00000356443(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P52179|rcsb pdb:2R15|rcsb pdb:2Y23|rcsb pdb:2Y25|rcsb pdb:3RBS|rcsb pdb:5FM4|rcsb pdb:5FM5|rcsb pdb:5FM8|rcsb pdb:6T3O|genbank_protein_gi:46249363(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5lfd5o+54eyer647zxvU0LX1wpM9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:39E05C7811E4EBF6|rigid:zJxhF1ADqWxN4zRruTqUvvmyRMQ	false	sufficient binding region:1082-1685(IPR003599)	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P52179	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5353249|uniprotkb:Q14BD6|uniprotkb:Q6H969|uniprotkb:Q6ZUU0|ensembl:ENSP00000348821	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:myom1_human(display_long)|uniprotkb:MYOM1(gene name)|psi-mi:MYOM1(display_short)|uniprotkb:190 kDa connectin-associated protein(gene name synonym)|uniprotkb:190 kDa titin-associated protein(gene name synonym)|uniprotkb:Myomesin family member 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5665987|imex:IM-16425-789	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	dip:DIP-59649N|refseq:NP_003794.3|refseq:NP_062830.1|ensembl:ENSG00000101605(gene)|ensembl:ENST00000356443(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P52179|rcsb pdb:2R15|rcsb pdb:2Y23|rcsb pdb:2Y25|rcsb pdb:3RBS|rcsb pdb:5FM4|rcsb pdb:5FM5|rcsb pdb:5FM8|rcsb pdb:6T3O|genbank_protein_gi:46249363(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:5lfd5o+54eyer647zxvU0LX1wpM9606	intact-crc:D69D0FF7872FCA19|rigid:zJxhF1ADqWxN4zRruTqUvvmyRMQ	false	sufficient binding region:2120-2564	sufficient binding region:949-1685(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P54296	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666005|imex:IM-16425-790	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296|genbank_protein_gi:31418211(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606	intact-crc:EFD1831CDF72A90B|rigid:imvOt5UAnUDJq5ZAscY+KiKLhEQ	false	sufficient binding region:29808-30118	sufficient binding region:854-1465(IPR007110)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8TD19	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-1044009|uniprotkb:Q52LK6|uniprotkb:Q8NCN0|uniprotkb:Q8TCY4|uniprotkb:Q9UPI4|uniprotkb:Q9Y6S4|uniprotkb:Q9Y6S5|uniprotkb:Q9Y6S6|intact:EBI-28978800|ensembl:ENSP00000238616	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:nek9_human(display_long)|uniprotkb:NEK9(gene name)|psi-mi:NEK9(display_short)|uniprotkb:KIAA1995(gene name synonym)|uniprotkb:NEK8(gene name synonym)|uniprotkb:NERCC(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 9(gene name synonym)|uniprotkb:Nercc1 kinase(gene name synonym)|uniprotkb:NimA-related kinase 8(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666023|imex:IM-16425-791	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_149107.4|ensembl:ENSG00000119638(gene)|ensembl:ENST00000238616(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011009(Protein kinase-like)|interpro:IPR042767|mint:Q8TD19|rcsb pdb:3ZKE|rcsb pdb:3ZKF|reactome:R-HSA-2980767|reactome:R-HSA-3301854|reactome:R-HSA-9648025|ensembl:ENSP00000238616|refseq:NP_001316166.1|refseq:NP_001316167.1|genbank_protein_gi:31543285(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:nH92Hku490dDttw5Akug+NjXRNY9606	intact-crc:CF0CD34C2738D444|rigid:z6gdp2rdRyXr2QUOebsnRa0P3mA	false	sufficient binding region:29808-30118	sufficient binding region:1-979	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92859	uniprotkb:Q8WZ42	intact:EBI-2829116|uniprotkb:B7ZKM9|uniprotkb:Q17RX1|uniprotkb:O00340|intact:EBI-28985104|uniprotkb:B7ZKN0|ensembl:ENSP00000261908|ensembl:ENSP00000341198	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:neo1_human(display_long)|uniprotkb:NEO1(gene name)|psi-mi:NEO1(display_short)|uniprotkb:IGDCC2(gene name synonym)|uniprotkb:NGN(gene name synonym)|uniprotkb:Immunoglobulin superfamily DCC subclass member 2(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666042|imex:IM-16425-792	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002490.2|refseq:NP_001166095.1|ensembl:ENSP00000261908|ensembl:ENSP00000341198|ensembl:ENST00000558964|ensembl:ENSP00000453200|ensembl:ENST00000560262|ensembl:ENSP00000453317|refseq:NP_001166094.1|dip:DIP-46272N|ensembl:ENSG00000067141(gene)|ensembl:ENST00000261908(transcript)|ensembl:ENST00000339362(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0039706"(co-receptor binding)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033024|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5F|rcsb pdb:1X5G|rcsb pdb:1X5H|rcsb pdb:1X5I|rcsb pdb:1X5J|rcsb pdb:1X5K|rcsb pdb:3P4L|reactome:R-HSA-373752|reactome:R-HSA-525793|genbank_protein_gi:4505374(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:qfhSmuj+gTFt2FkBaL/aUUWeKrY9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:3D3F0AC196826067|rigid:T/Pt4buSfUJgUOx8Z6aoEGIwcjc	false	sufficient binding region:489-1461(IPR003961)	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VST9	uniprotkb:Q8WZ42	intact:EBI-941850|uniprotkb:Q2A664|uniprotkb:Q5T7G8|uniprotkb:Q5T7G9|uniprotkb:Q5VSU2|uniprotkb:Q86YC7|uniprotkb:Q8NHN0|uniprotkb:Q8NHN1|uniprotkb:Q8NHN2|uniprotkb:Q8NHN3|uniprotkb:Q8NHN4|uniprotkb:Q8NHN5|uniprotkb:Q8NHN6|uniprotkb:Q8NHN7|uniprotkb:Q8NHN8|uniprotkb:Q8NHN9|uniprotkb:Q96AA2|uniprotkb:Q9HCD3|uniprotkb:Q9HCL6|ensembl:ENSP00000409493	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:obscn_human(display_long)|uniprotkb:OBSCN(gene name)|psi-mi:OBSCN(display_short)|uniprotkb:KIAA1639(gene name synonym)|uniprotkb:Obscurin-myosin light chain kinase(gene name synonym)|uniprotkb:Obscurin-RhoGEF(gene name synonym)|uniprotkb:KIAA1556(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666060|imex:IM-16425-793	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000284548|ensembl:ENSP00000284548|ensembl:ENSP00000409493|ensembl:ENST00000636476|ensembl:ENSP00000489816|ensembl:ENST00000662438|ensembl:ENSP00000499633|refseq:NP_001092093.2|refseq:NP_443075.3|dip:DIP-35727N|ensembl:ENSG00000154358(gene)|ensembl:ENST00000422127(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0042383"(sarcolemma)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020682|interpro:IPR035526|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1V1C|rcsb pdb:2CR6|rcsb pdb:2DKU|rcsb pdb:2DM7|rcsb pdb:2E7B|rcsb pdb:2EDF|rcsb pdb:2EDH|rcsb pdb:2EDL|rcsb pdb:2EDQ|rcsb pdb:2EDR|rcsb pdb:2EDT|rcsb pdb:2EDW|rcsb pdb:2ENY|rcsb pdb:2EO1|rcsb pdb:2GQH|rcsb pdb:2MWC|rcsb pdb:2N56|rcsb pdb:2YZ8|rcsb pdb:4C4K|rcsb pdb:4RSV|rcsb pdb:4UOW|rcsb pdb:5TZM|rcsb pdb:6MG9|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013406|genbank_protein_gi:22046663(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:pUzPNEELWyEtZa4+ra9kGoGMntc9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:0C58B9C6DDB0330A|rigid:AgzQUMkdqxzd6jiRILwsZ/eSrYg	false	sufficient binding region:2572-7968	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8TEW0	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666077|imex:IM-16425-794	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N|genbank_protein_gi:14579310(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	intact-crc:5D7E3474D2FCF5E8|rigid:xIrGkLDrzgRcGyoR8eGUOTrDNOg	false	sufficient binding region:2120-2564	sufficient binding region:591-1356	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43175	uniprotkb:Q8WZ42	intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|ensembl:ENSP00000493175|ensembl:ENSP00000493382|uniprotkb:B2RD08	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666094|imex:IM-16425-795	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006614.2|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|ensembl:ENSG00000092621(gene)|ensembl:ENST00000641023(transcript)|ensembl:ENST00000641597(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|reactome:R-HSA-977347|genbank_protein_gi:33875271(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:173674252CD0F1D0|rigid:n+qdpg0wgzDsMo7HNuATfAnmXeE	false	sufficient binding region:94-533	sufficient binding region:2120-2564	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30050	uniprotkb:Q8WZ42	intact:EBI-352743|uniprotkb:Q6PB27|uniprotkb:Q5VVV2|ensembl:ENSP00000354739	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:rl12_human(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666111|imex:IM-16425-796	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000967.1|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P30050|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|genbank_protein_gi:15431291(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:TNPEtl60cILofaPzUznvZiw6D7E9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:FC4234A0E722A82B|rigid:T4OD8bjT7VWYgiHk9u5vCk5Swtk	false	sufficient binding region:32-165(IPR000911)	sufficient binding region:2120-2564	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:P21817	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-1221290|uniprotkb:Q16314|uniprotkb:Q16368|uniprotkb:Q9NPK1|uniprotkb:Q9P1U4|ensembl:ENSP00000352608	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:ryr1_human(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:RYDR(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666129|imex:IM-16425-797	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_000531.2|refseq:NP_001036188.1|dip:DIP-29708N|ensembl:ENSG00000196218(gene)|ensembl:ENST00000359596(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031674"(I band)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:6UHI|rcsb pdb:6UHS|reactome:R-HSA-2672351|reactome:R-HSA-5578775|genbank_protein_gi:113204616(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:WHlPtd5++5f+9GX0IGshsqJCOTg9606	intact-crc:2B53B25EA9E5D376|rigid:apkhn4VwWyix4H1gN067VeVil2A	false	sufficient binding region:29808-30118	sufficient binding region:1053-5038	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15637	uniprotkb:Q8WZ42	intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666146|imex:IM-16425-798	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N|genbank_protein_gi:42544122(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:7AAD6E504D4C4AA3|rigid:TSb02B5KJy+fyixxgKVX39ruHr0	false	sufficient binding region:78-639	sufficient binding region:31800-31981	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NYJ8	uniprotkb:Q8WZ42	intact:EBI-358708|uniprotkb:O94838|uniprotkb:Q6I9W8|uniprotkb:Q76N06|uniprotkb:Q9UFP7|uniprotkb:E1P5A0|uniprotkb:B2RCC4|ensembl:ENSP00000356426|ensembl:ENSP00000445752|ensembl:ENSP00000490618	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:tab2_human(display_long)|uniprotkb:TAB2(gene name)|psi-mi:TAB2(display_short)|uniprotkb:KIAA0733(gene name synonym)|uniprotkb:MAP3K7IP2(gene name synonym)|uniprotkb:TAK1-binding protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase 7-interacting protein 2(gene name synonym)|uniprotkb:TGF-beta-activated kinase 1-binding protein 2(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666163|imex:IM-16425-799	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055908.1|refseq:NP_001278963.1|refseq:NP_001278964.1|refseq:XP_011533935.1|ensembl:ENST00000637181(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENST00000538427(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007507"(heart development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR036443|interpro:IPR041911|mint:Q9NYJ8|rcsb pdb:2DAE|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1|reactome:R-HSA-1251985|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|ensembl:ENST00000367456(transcript)|ensembl:ENSG00000055208(gene)|refseq:XP_016866080.1|refseq:XP_016866081.1|dip:DIP-27525N|genbank_protein_gi:21735557(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:hMWL5GobXJSsm8ToWVBF/ZwPX3M9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:85C819A5C3B4AF03|rigid:Aa0J1i7kN8o0/ps0RMsYXMMQJxc	false	sufficient binding region:439-693	sufficient binding region:8831-9158	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53804	uniprotkb:Q8WZ42	intact:EBI-2681313|uniprotkb:P78477|uniprotkb:A8K7H7|uniprotkb:Q9UEK4|uniprotkb:Q569I2|uniprotkb:Q6P578|uniprotkb:B2RPA7|uniprotkb:O60767|uniprotkb:P78476|uniprotkb:D3DSG9|uniprotkb:D3DSH2|uniprotkb:D3DSH3|intact:EBI-28966952|ensembl:ENSP00000346791|ensembl:ENSP00000347889|ensembl:ENSP00000381981	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:ttc3_human(display_long)|uniprotkb:DCRR1(gene name synonym)|uniprotkb:RNF105(gene name synonym)|uniprotkb:TPRD(gene name synonym)|uniprotkb:Protein DCRR1(gene name synonym)|uniprotkb:RING finger protein 105(gene name synonym)|uniprotkb:TPR repeat protein D(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 3(gene name synonym)|uniprotkb:TTC3(gene name)|psi-mi:TTC3(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TTC3(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666180|imex:IM-16425-800	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000346791|ensembl:ENSP00000347889|ensembl:ENSP00000381981|refseq:NP_001307633.1|refseq:XP_011528042.1|refseq:NP_001001894.1|refseq:NP_003307.3|refseq:NP_001317610.1|refseq:NP_001317611.1|refseq:NP_001317612.1|ensembl:ENSG00000182670(gene)|ensembl:ENST00000354749(transcript)|ensembl:ENST00000355666(transcript)|ensembl:ENST00000399017(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR043866|genbank_protein_gi:49640010(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:AUMk8fif75q+OlZMhyo2I95YkXQ9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:7925E57911EE2B17|rigid:QEI8xNWRize8cNpct/wRHcCKm2w	false	sufficient binding region:1416-2025	sufficient binding region:31800-31981	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666197|imex:IM-16425-801	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:7B05B4FE3E9EAE05|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:29808-30118	sufficient binding region:5976-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666215|imex:IM-16425-802	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:0290042FBA29CE48|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:29808-30118	sufficient binding region:19593-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666234|imex:IM-16425-803	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:B6783E20DDD18BDD|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:28300-34350(IPR003599)	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666253|imex:IM-16425-804	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:8EDD6807CBF95ED4|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:29808-30118	sufficient binding region:21799-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666271|imex:IM-16425-805	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:6A164D529F8378CB|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:30099-34350(IPR003961)	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666289|imex:IM-16425-806	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:95BFFBD2DECB7A46|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:16053-34350(IPR003961)	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666307|imex:IM-16425-807	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:ED85511B97F9E647|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:15712-34350(IPR003961)	sufficient binding region:29808-30118	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666325|imex:IM-16425-808	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:BF27C1BDEC5D6635|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:29808-30118	sufficient binding region:26931-34350(IPR003961)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666344|imex:IM-16425-809	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2022/01/25	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:9B2E75AC5C975A0F|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:18781-34350(IPR007110)	sufficient binding region:2120-2564	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666362|imex:IM-16425-810	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:D56CE568E8A995EA|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:29693-34350(IPR003599)	sufficient binding region:2120-2564	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666380|imex:IM-16425-811	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:B8E9B03DDED89D40|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:2120-2564	sufficient binding region:26083-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666399|imex:IM-16425-812	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:8A931B1DA98AC9AD|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:29317-34350(IPR003961)	sufficient binding region:2120-2564	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666418|imex:IM-16425-813	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:2C58F13112783733|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:32840-33423	sufficient binding region:27495-34350(IPR003599)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ42	uniprotkb:Q8WZ42	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666437|imex:IM-16425-814	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:81370F26595A0B0D|rigid:AlU3Ce6DcEq3AFTUjfn3KHz+298	false	sufficient binding region:24800-34350(IPR003961)	sufficient binding region:32840-33423	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q8WZ42	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666456|imex:IM-16425-815	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|genbank_protein_gi:35493970(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:AF01B28B12520AE2|rigid:+7VzGHqOWelWmH4zx4z7iPwB65A	false	sufficient binding region:1-158	sufficient binding region:8831-9158	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16851	uniprotkb:Q8WZ42	intact:EBI-743729|intact:EBI-1759682|uniprotkb:Q07131|uniprotkb:Q0P6K2|uniprotkb:Q86Y81|uniprotkb:Q9BU15|intact:EBI-1964706|ensembl:ENSP00000338703	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:ugpa_human(display_long)|uniprotkb:UDP-glucose pyrophosphorylase(gene name synonym)|uniprotkb:UGP2(gene name)|psi-mi:UGP2(display_short)|uniprotkb:UGP1(gene name synonym)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666473|imex:IM-16425-816	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005264594.1|refseq:XP_005264595.1|refseq:NP_001001521.1|refseq:NP_006750.3|ensembl:ENSG00000169764(gene)|ensembl:ENST00000337130(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005536"(glucose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0032557"(pyrimidine ribonucleotide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044|rcsb pdb:3R2W|rcsb pdb:3R3I|rcsb pdb:4R7P|reactome:R-HSA-173599|reactome:R-HSA-3322077|genbank_protein_gi:48255967(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:QfrqJrPLyviX6V6RotwJ23c9fBo9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:86785A7E628CAD09|rigid:00ZNG0uxLpe80RUNo+9dCOvE07g	false	sufficient binding region:79-508(IPR002618)	sufficient binding region:2120-2564	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52735	uniprotkb:Q8WZ42	intact:EBI-297549|ensembl:ENSP00000360916|uniprotkb:A2RUM4|uniprotkb:A8MQ12|uniprotkb:Q5SYV3|uniprotkb:Q5SYV4|uniprotkb:Q5SYV5|uniprotkb:Q6N012|uniprotkb:Q6PIJ9|uniprotkb:Q6Q317|uniprotkb:B6ZDF5	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:vav2_human(display_long)|uniprotkb:VAV2(gene name)|psi-mi:VAV2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666491|imex:IM-16425-817	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160293(gene)|ensembl:ENST00000371850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030168"(platelet activation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P52735|rcsb pdb:2DLZ|rcsb pdb:2DM1|rcsb pdb:2LNW|rcsb pdb:2LNX|rcsb pdb:4ROJ|reactome:R-HSA-114604|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2424491|reactome:R-HSA-2871796|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|reactome:R-HSA-2871809|reactome:R-HSA-3928665|reactome:R-HSA-416482|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|reactome:R-HSA-4420097|refseq:NP_001127870.1|refseq:NP_003362.2|refseq:XP_005272270.1|dip:DIP-33088N|genbank_protein_gi:40549447(identity)	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N|genbank_protein_gi:110349718(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:usp18HylJidh6mU3Zf0cAzo5ABM9606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	intact-crc:C5F0FA3C931BA0BA|rigid:x5Cg5yUrnYtjZhAtWo5InanJLHI	false	sufficient binding region:551-878	sufficient binding region:8831-9158	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:P35609	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666508|imex:IM-16425-818	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|genbank_protein_gi:178053(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	intact-crc:AA36A58BD5F97FE1|rigid:5YkpqgvYn9/kLmtBP4uNjbSyoXo	false	sufficient binding region:1-442	sufficient binding region:480-894(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q99996-1	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-20222842	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:q99996-1(display_long)|uniprotkb:A-kinase anchor protein 350 kDa(gene name synonym)|uniprotkb:A-kinase anchor protein 450 kDa(gene name synonym)|uniprotkb:AKAP 120-like protein(gene name synonym)|uniprotkb:AKAP9(gene name)|psi-mi:AKAP9(display_short)|uniprotkb:AKAP350(gene name synonym)|uniprotkb:AKAP450(gene name synonym)|uniprotkb:Centrosome- and Golgi-localized PKN-associated protein(gene name synonym)|uniprotkb:KIAA0803(gene name synonym)|uniprotkb:Protein hyperion(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym)|uniprotkb:Protein yotiao(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666526|imex:IM-16425-819	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	intact:EBI-1048311(isoform-parent)|genbank_protein_gi:22538388(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/30	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:It7bl8awFkbWOI9+QlUndtSJI3g9606	intact-crc:C29ED4BE1F1065DF|rigid:KePxEPJmDZmpdkL6S0DtUb9UzRQ	false	sufficient binding region:1-442	sufficient binding region:1001-1645	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q5T5U3	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-1642518|uniprotkb:Q8NI19|uniprotkb:Q0VF98|uniprotkb:Q7Z3P7|uniprotkb:Q8N3A2|uniprotkb:Q8TBV5|uniprotkb:Q9P2C3|ensembl:ENSP00000379709	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:rhg21_human(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 21(gene name synonym)|uniprotkb:Rho GTPase-activating protein 10(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666543|imex:IM-16425-820	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_065875.3|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9013148|ensembl:ENSG00000107863(gene)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051645"(Golgi localization)|ensembl:ENST00000396432(transcript)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR000198(RhoGAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR041489|mint:Q5T5U3|rcsb pdb:2DHJ|rcsb pdb:2J59|rcsb pdb:2YUY|reactome:R-HSA-8980692|reactome:R-HSA-9013026|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9013106|refseq:XP_005252599.1|refseq:XP_016871948.1|genbank_protein_gi:50345878(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2019/02/20	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606	intact-crc:2DCC3C3C742E1A6A|rigid:5FuYTCKVzomrHIZ/m6T+OEIYl1k	false	sufficient binding region:1-442	sufficient binding region:1521-1958	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q7L311	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-474133|uniprotkb:O60267|uniprotkb:Q5H9D9|ensembl:ENSP00000328631|ensembl:ENSP00000331662|ensembl:ENSP00000349281	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:armx2_human(display_long)|uniprotkb:ARM protein lost in epithelial cancers on chromosome X 2(gene name synonym)|uniprotkb:ARMCX2(gene name)|psi-mi:ARMCX2(display_short)|uniprotkb:KIAA0512(gene name synonym)|uniprotkb:ALEX2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666560|imex:IM-16425-821	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	ensembl:ENSG00000184867(gene)|ensembl:ENST00000328766(transcript)|ensembl:ENST00000330154(transcript)|ensembl:ENST00000356824(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000225(Armadillo)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_055597.1|refseq:NP_808818.1|refseq:XP_011529373.1|refseq:XP_011529374.1|refseq:NP_001269160.1|refseq:XP_005278166.1|refseq:XP_005278167.1|refseq:XP_005278168.1|refseq:XP_005278170.1|refseq:XP_005278171.1|refseq:XP_005278172.1|refseq:XP_005278173.1|refseq:XP_005278174.1|refseq:XP_016885476.1|refseq:XP_016885477.1|refseq:XP_016885478.1|refseq:XP_016885479.1|refseq:XP_016885480.1|refseq:XP_016885481.1|refseq:XP_016885482.1|refseq:XP_016885483.1|refseq:XP_016885484.1|refseq:XP_016885485.1|refseq:XP_016885486.1|genbank_protein_gi:41327765(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:h9mWdWiqZT8ZPNvbALuQNyfghks9606	intact-crc:816EE346330A7D0C|rigid:+DeB1nwmD/YcNOMoy56CEeCaG8E	false	sufficient binding region:1-442	sufficient binding region:274-632(IPR000225)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14983	uniprotkb:O75386	intact:EBI-359186|uniprotkb:O14984|uniprotkb:A8K5J9|ensembl:ENSP00000349595|uniprotkb:B3KY17	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:at2a1_human(display_long)|uniprotkb:ATP2A1(gene name)|psi-mi:ATP2A1(display_short)|uniprotkb:Calcium pump 1(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666579|imex:IM-16425-822	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004311.1|refseq:NP_775293.1|ensembl:ENSG00000196296(gene)|ensembl:ENST00000357084(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0031673"(H zone)|go:"GO:0031674"(I band)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034704"(calcium channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:0106134"(positive regulation of cardiac muscle cell contraction)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902082"(positive regulation of calcium ion import into sarcoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O14983|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001273004.1|genbank_protein_gi:47132613(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3cHH/E8HuaFCoTd7hO/0SFTnqtg9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:DF4E9585D593F5F8|rigid:DqGVK7OPUDEZ6lvXNoVN2qZc8AY	false	sufficient binding region:658-1001(IPR000695)	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q9BWV1	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-718555|uniprotkb:A6NJ30|uniprotkb:Q6UXJ5|uniprotkb:Q8N2P7|uniprotkb:Q8NF26|uniprotkb:B2RMS8|uniprotkb:D3DN70|ensembl:ENSP00000347546|ensembl:ENSP00000418663	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:boc_human(display_long)|uniprotkb:BOC(gene name)|psi-mi:BOC(display_short)|uniprotkb:UNQ604/PRO1190(orf name)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666598|imex:IM-16425-823	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_150279.1|refseq:XP_016862940.1|refseq:XP_011511607.1|refseq:NP_001288790.1|refseq:XP_005247948.1|refseq:XP_005247949.1|ensembl:ENSG00000144857(gene)|ensembl:ENST00000355385(transcript)|ensembl:ENST00000495514(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0045663"(positive regulation of myoblast differentiation)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032982|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3N1G|rcsb pdb:3N1M|rcsb pdb:3N1P|reactome:R-HSA-525793|reactome:R-HSA-5632681|reactome:R-HSA-5635838|interpro:IPR003598(Immunoglobulin subtype 2)|genbank_protein_gi:38372928(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:SQPC0pqcAHVfuJCxq84BSi9k0IA9606	intact-crc:91E872046DECA810|rigid:Ow31eyhfyEqfxVwk04/G+AqiP3Y	false	sufficient binding region:1-442	sufficient binding region:407-1114	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5PSV4	uniprotkb:O75386	intact:EBI-5666615|intact:EBI-11060846|uniprotkb:Q9BRI4|uniprotkb:A6NFW5|uniprotkb:A6NH45|uniprotkb:B2RD65|ensembl:ENSP00000216807	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:brm1l_human(display_long)|uniprotkb:BRMS1-homolog protein p40(gene name synonym)|uniprotkb:BRMS1-like protein p40(gene name synonym)|uniprotkb:BRMS1L(gene name)|psi-mi:BRMS1L(display_short)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666622|imex:IM-16425-824	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006720338.1|refseq:NP_115728.2|refseq:XP_016877193.1|refseq:XP_016877194.1|ensembl:ENSG00000100916(gene)|ensembl:ENST00000216807(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR013907(Sds3-like)|mint:Q5PSV4|genbank_protein_gi:68348706(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:jVvtmlOL9vQdYz5kAnOi6GksVng9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:953ED0AE2BDC2BEF|rigid:DvT/Fs24GHho66SsMMeY3ZuGXhM	false	sufficient binding region:1-323	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q9H0C5	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-935503|uniprotkb:A6NMI8|uniprotkb:Q9BX71|uniprotkb:Q9NWN4|ensembl:ENSP00000261721	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:btbd1_human(display_long)|uniprotkb:BTBD1(gene name)|psi-mi:BTBD1(display_short)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 8(gene name synonym)|uniprotkb:NS5ATP8(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666639|imex:IM-16425-825	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_001011885.1|refseq:NP_079514.1|ensembl:ENSG00000064726(gene)|ensembl:ENST00000261721(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR012983(PHR)|interpro:IPR038648|reactome:R-HSA-8951664|reactome:R-HSA-983168|genbank_protein_gi:59814145(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:fRSh7JVRI2O2o8m7WCEjydcX1QM9606	intact-crc:73A3E51686406C4A|rigid:G+557E+IHbIj1M/rHJhMOj7ZySs	false	sufficient binding region:1-442	sufficient binding region:100-482(IPR000210)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NWQ4	uniprotkb:O75386	intact:EBI-5666657|uniprotkb:Q9ULR8|uniprotkb:Q9H3M3|uniprotkb:B3KN42|uniprotkb:Q9NWH0|uniprotkb:Q6PEJ7|intact:EBI-28984791|ensembl:ENSP00000261530	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:gpt2l_human(display_long)|uniprotkb:GPATCH2L(gene name)|psi-mi:GPATCH2L(display_short)|uniprotkb:C14orf118(gene name synonym)|uniprotkb:KIAA1152(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666666|imex:IM-16425-826	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060396.2|refseq:NP_060442.2|ensembl:ENSP00000261530|ensembl:ENST00000312858|ensembl:ENSP00000323775|ensembl:ENST00000556663|ensembl:ENSP00000450657|ensembl:ENST00000557263|ensembl:ENSP00000451587|ensembl:ENST00000621494|ensembl:ENSP00000480608|ensembl:ENSG00000089916(gene)|ensembl:ENST00000261530(transcript)|mint:Q9NWQ4|genbank_protein_gi:40018643(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:d87RToTsMGv1/VCmPi3ivMXaM6k9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:AA6B0C486FD9CFEB|rigid:MenUGXoVKxp1p/lVxeWxgmlpLfk	false	sufficient binding region:160-482	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14635	uniprotkb:O75386	intact:EBI-495332|uniprotkb:A8K066|uniprotkb:Q5TZP9|ensembl:ENSP00000256442	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:ccnb1_human(display_long)|uniprotkb:CCNB1(gene name)|psi-mi:CCNB1(display_short)|uniprotkb:CCNB(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666683|imex:IM-16425-827	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114172.1|dip:DIP-59N|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042493"|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046680"(response to DDT)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048565"(digestive tract development)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|ensembl:ENSG00000134057(gene)|ensembl:ENST00000256442(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005113"(patched binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|go:"GO:2000775"(obsolete histone H3-S10 phosphorylation involved in chromosome condensation)|interpro:IPR004367(Cyclin, C-terminal)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071283"("cellular response to iron(III) ion")|interpro:IPR039361|mint:P14635|rcsb pdb:2B9R|rcsb pdb:2JGZ|rcsb pdb:4Y72|rcsb pdb:4YC3|go:"GO:0071398"(cellular response to fatty acid)|rcsb pdb:5HQ0|go:"GO:0071407"(cellular response to organic cyclic compound)|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|reactome:R-HSA-113507|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174048|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|go:"GO:0071456"(cellular response to hypoxia)|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-4419969|reactome:R-HSA-6804114|reactome:R-HSA-68875|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8878166|reactome:R-HSA-8852276|genbank_protein_gi:34304372(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:WCQWqI2kWZfatq4L2DC0hm26Ix09606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:2F13193ADB64D9BA|rigid:Dusqcz7K5hG0HuiJTxrefNQ7Xmc	false	sufficient binding region:1-433(IPR006671)	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14647	uniprotkb:O75386	intact:EBI-1210503|uniprotkb:C6G482|uniprotkb:Q96IP5|ensembl:ENSP00000377747	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:chd2_human(display_long)|uniprotkb:CHD2(gene name)|psi-mi:CHD2(display_short)|uniprotkb:ATP-dependent helicase CHD2(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666702|imex:IM-16425-828	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001262.3|refseq:NP_001036037.1|interpro:IPR023780|interpro:IPR025260|interpro:IPR027417|interpro:IPR038718|interpro:IPR040793|mint:O14647|interpro:IPR023779|ensembl:ENSG00000173575(gene)|ensembl:ENST00000394196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007517"(muscle organ development)|go:"GO:0042393"(histone binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|genbank_protein_gi:118421088(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Vibq3UdOTD39yhVlCgkyhzxw1Zw9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:7D5CBF0A7EB02E31|rigid:IvrJaF9AKzA2203a+vk7YwhI3wE	false	sufficient binding region:175-1828	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q8N3C7	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666719|imex:IM-16425-829	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W|genbank_protein_gi:31982880(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606	intact-crc:3197E883D3E5A96F|rigid:HAvU14sebEeI37yKzTEjhBakk0k	false	sufficient binding region:1-442	sufficient binding region:209-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5QJE6	uniprotkb:O75386	intact:EBI-5666736|ensembl:ENSP00000411010|uniprotkb:Q53H59|uniprotkb:Q86WX9|uniprotkb:Q76MJ8|uniprotkb:Q12987|uniprotkb:Q6TLI0|uniprotkb:Q5TFJ4	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:tdif2_human(display_long)|uniprotkb:ERBP(gene name synonym)|uniprotkb:Estrogen receptor-binding protein(gene name synonym)|uniprotkb:LPTS-interacting protein 2(gene name synonym)|uniprotkb:TDIF2(gene name synonym)|uniprotkb:Terminal deoxynucleotidyltransferase-interacting factor 2(gene name synonym)|uniprotkb:DNTTIP2(gene name)|psi-mi:DNTTIP2(display_short)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666746|imex:IM-16425-830	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000067334(gene)|ensembl:ENST00000436063(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR014810(Fcf2 pre-rRNA processing)|interpro:IPR039883|refseq:NP_055412.2|genbank_protein_gi:54633314(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:GSN2/hZ+HZb29LuBvv2RVMawmNA9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:2E1032229C036CE5|rigid:uSG7YUzOksNKS4IuNw468EU+UlI	false	sufficient binding region:502-756	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NRR4	uniprotkb:O75386	intact:EBI-528367|uniprotkb:Q7Z5V2|uniprotkb:Q86YH0|uniprotkb:Q9NW73|uniprotkb:Q9Y2V9|uniprotkb:Q9Y4Y0|intact:EBI-10973107|uniprotkb:E7EMP9|ensembl:ENSP00000339845|ensembl:ENSP00000425979	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:rnc_human(display_long)|uniprotkb:Ribonuclease III(gene name synonym)|uniprotkb:DROSHA(gene name)|psi-mi:DROSHA(display_short)|uniprotkb:p241(gene name synonym)|uniprotkb:RNASEN(gene name synonym)|uniprotkb:RN3(gene name synonym)|uniprotkb:RNASE3L(gene name synonym)|uniprotkb:Protein Drosha(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666763|imex:IM-16425-831	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001093882.1|refseq:NP_037367.3|refseq:XP_005248348.1|refseq:XP_005248351.1|ensembl:ENSG00000113360(gene)|ensembl:ENST00000344624(transcript)|ensembl:ENST00000511367(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070877"(microprocessor complex)|go:"GO:0070878"(primary miRNA binding)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000999(Ribonuclease III)|interpro:IPR011907(Ribonuclease III, bacterial)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036389|interpro:IPR044442|rcsb pdb:2KHX|rcsb pdb:2NA2|rcsb pdb:5B16|rcsb pdb:6LXD|rcsb pdb:6LXE|rcsb pdb:6V5B|rcsb pdb:6V5C|reactome:R-HSA-203927|dip:DIP-33300N|genbank_protein_gi:21359821(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vHfmSHxD1M/Sh4dbo2S7FBaE+eQ9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:38614D19A78CAC1E|rigid:WoedD4rv8PY20SOcpG9txEOgBAY	false	sufficient binding region:414-1374	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q03001	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666780|imex:IM-16425-832	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	intact-crc:62C9EF579D5BB20D|rigid:3J6j1Sk07nTSlVnQT8gIYET5zls	false	sufficient binding region:1-442	sufficient binding region:3714-7570(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03001	uniprotkb:O75386	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666798|imex:IM-16425-833	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|genbank_protein_gi:34577048(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:DD6547FF044B1543|rigid:3J6j1Sk07nTSlVnQT8gIYET5zls	false	sufficient binding region:4263-7570(IPR002017)	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62508	uniprotkb:O75386	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666816|imex:IM-16425-834	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1|genbank_protein_gi:45545426(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:BA8572D2149D268C|rigid:fqEYp3qrb6VpOePk2bEF+laUUs0	false	sufficient binding region:4-458	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14687	uniprotkb:O75386	intact:EBI-372619|uniprotkb:Q8IY61|uniprotkb:Q96GA4|uniprotkb:Q9BW09|uniprotkb:D3DUM4|ensembl:ENSP00000253458	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:gse1_human(display_long)|uniprotkb:GSE1(gene name)|psi-mi:GSE1(display_short)|uniprotkb:KIAA0182(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666833|imex:IM-16425-835	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127945.1|refseq:NP_055430.1|refseq:NP_001265113.1|ensembl:ENSG00000131149(gene)|ensembl:ENST00000253458(transcript)|interpro:IPR022207|interpro:IPR042337|genbank_protein_gi:44955925(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:demu8MwWIxvbEfrM+pBn3gDTUO09606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:13D9521DCFC566B5|rigid:Wv/pq8xyMr+h4kTIEDTpeHVPTsA	false	sufficient binding region:1032-1217..1217	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y496	uniprotkb:O75386	intact:EBI-1104844|uniprotkb:Q59EN1|uniprotkb:Q86XE9|uniprotkb:Q9Y6V4|uniprotkb:A8MSW9|ensembl:ENSP00000368020	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:kif3a_human(display_long)|uniprotkb:KIF3A(gene name)|psi-mi:KIF3A(display_short)|uniprotkb:KIF3(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3A(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666850|imex:IM-16425-836	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001287720.1|refseq:NP_001287721.1|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006996"(organelle organization)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0097542"(ciliary tip)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q9Y496|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5610787|reactome:R-HSA-5620924|reactome:R-HSA-5635838|reactome:R-HSA-6811434|reactome:R-HSA-983189|ensembl:ENSG00000131437(gene)|ensembl:ENST00000378746(transcript)|go:"GO:0003777"(microtubule motor activity)|refseq:NP_008985.3|dip:DIP-33237N|genbank_protein_gi:33620740(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:mqR9jDCvk8dXn0mi2WvmnMNR1UQ9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:0B9C0D44EA7D3551|rigid:EoDUO++trUapE5BkUn08rqtefic	false	sufficient binding region:375-699	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13118	uniprotkb:O75386	intact:EBI-1389509|uniprotkb:Q503B2|uniprotkb:B2R794|intact:EBI-3962407|uniprotkb:A8MVH0|uniprotkb:O75411|uniprotkb:L0R4P6|uniprotkb:L0R679|ensembl:ENSP00000285407	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:klf10_human(display_long)|uniprotkb:Transforming growth factor-beta-inducible early growth response protein 1(gene name synonym)|uniprotkb:EGR-alpha(gene name synonym)|uniprotkb:KLF10(gene name)|psi-mi:KLF10(display_short)|uniprotkb:TIEG(gene name synonym)|uniprotkb:TIEG1(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666867|imex:IM-16425-837	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027453.1|refseq:NP_005646.1|ensembl:ENSG00000155090(gene)|ensembl:ENST00000285407(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0030282"(bone mineralization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2EPA|genbank_protein_gi:73760402(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zn9npr6/dmo7T/4AiUnHQPHR4409606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:F22B228F69D90871|rigid:UiPsJ21mvrxKPzu7uLfSRyK1mhs	false	sufficient binding region:296-480(IPR007087)	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99683	uniprotkb:O75386	intact:EBI-476263|uniprotkb:Q5THN3|uniprotkb:Q99461|uniprotkb:A6NIA0|uniprotkb:B4DGB2|ensembl:ENSP00000351908	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:m3k5_human(display_long)|uniprotkb:MAPK/ERK kinase kinase 5(gene name synonym)|uniprotkb:Apoptosis signal-regulating kinase 1(gene name synonym)|uniprotkb:MAP3K5(gene name)|psi-mi:MAP3K5(display_short)|uniprotkb:ASK1(gene name synonym)|uniprotkb:MAPKKK5(gene name synonym)|uniprotkb:MEKK5(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666885|imex:IM-16425-838	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005914.1|dip:DIP-29516N|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|ensembl:ENSG00000197442(gene)|ensembl:ENST00000359015(transcript)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072577"(endothelial cell apoptotic process)|go:"GO:0090398"(cellular senescence)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902911"(protein kinase complex)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025136|interpro:IPR043969|mint:Q99683|rcsb pdb:2CLQ|rcsb pdb:3VW6|rcsb pdb:4BF2|rcsb pdb:4BHN|rcsb pdb:4BIB|rcsb pdb:4BIC|rcsb pdb:4BID|rcsb pdb:4BIE|rcsb pdb:5ULM|rcsb pdb:5UOR|rcsb pdb:5UOX|rcsb pdb:5UP3|rcsb pdb:5V19|rcsb pdb:5V24|rcsb pdb:5VIL|rcsb pdb:5VIO|rcsb pdb:6E2M|rcsb pdb:6E2N|rcsb pdb:6E2O|rcsb pdb:6EJL|rcsb pdb:6OYT|rcsb pdb:6OYW|rcsb pdb:6VRE|rcsb pdb:6XIH|reactome:R-HSA-2559580|genbank_protein_gi:21536459(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:/txMHg7GSCpK8ij48YDHGARX3es9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:BAC89CE1146C47D9|rigid:PbMY8rVpAogJxKwEj9SCbF7vIQI	false	sufficient binding region:962-1374	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q05BQ5	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-5666902|uniprotkb:Q9NXU1|uniprotkb:Q6ZVU7|ensembl:ENSP00000403946|ensembl:ENSP00000468304	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:mbtd1_human(display_long)|uniprotkb:MBTD1(gene name)|psi-mi:MBTD1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666908|imex:IM-16425-839	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:XP_011523238.1|refseq:NP_060113.2|ensembl:ENSG00000011258(gene)|ensembl:ENST00000415868(transcript)|ensembl:ENST00000586178(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038603|mint:Q05BQ5|rcsb pdb:3FEO|rcsb pdb:4C5I|rcsb pdb:6NFX|genbank_protein_gi:158508475(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:Osdh7GfOtCTGyigRfOAYp5sL84Y9606	intact-crc:42B98758BB01C2AA|rigid:EPAi2gHwrMDTeDUhKPsmMpSfrXk	false	sufficient binding region:1-442	sufficient binding region:1-628	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWI9	uniprotkb:O75386	intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666925|imex:IM-16425-840	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|genbank_protein_gi:122937387(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2019/07/09	rogid:P4lo9EteCvikQQk5kyVkcobitLU9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:1E9693CF40F35AD2|rigid:Q2vQQxyNIs8LtMFYDJGBQFHfkA4	false	sufficient binding region:757-1126	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBU8	uniprotkb:O75386	intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666942|imex:IM-16425-841	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847|genbank_protein_gi:33337721(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:28GQifqUMxwR32cneTXH+lpW4gM9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:0664C5D2B2EEDD4C|rigid:Pzj1cut0iWjOwa/WzcgSCVm3lcQ	false	sufficient binding region:182-362(IPR008676)	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14324	uniprotkb:O75386	intact:EBI-5653200|uniprotkb:A1L4G9|ensembl:ENSP00000350332	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:mypc2_human(display_long)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)|uniprotkb:MYBPCF(gene name synonym)|uniprotkb:MYBPC2(gene name)|psi-mi:MYBPC2(display_short)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666960|imex:IM-16425-842	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004524.3|ensembl:ENSG00000086967(gene)|ensembl:ENST00000357701(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14324|rcsb pdb:2E7C|rcsb pdb:2EDK|rcsb pdb:2EDN|reactome:R-HSA-390522|genbank_protein_gi:55956911(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:vXzXuvIYS8hBx+L1gx3KH7fRA+Y9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:102B295BA1321B05|rigid:lmQmy/GddhzWMpewm/59k6qPEA8	false	sufficient binding region:236-1141(IPR001394)	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11055	uniprotkb:O75386	intact:EBI-5654298|uniprotkb:Q15492|ensembl:ENSP00000464317	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:myh3_human(display_long)|uniprotkb:Muscle embryonic myosin heavy chain(gene name synonym)|uniprotkb:Myosin heavy chain 3(gene name synonym)|uniprotkb:Myosin heavy chain, fast skeletal muscle, embryonic(gene name synonym)|uniprotkb:SMHCE(gene name synonym)|uniprotkb:MYH3(gene name)|psi-mi:MYH3(display_short)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666979|imex:IM-16425-843	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011522172.1|refseq:XP_011522173.1|refseq:NP_002461.2|ensembl:ENSG00000109063(gene)|ensembl:ENST00000583535(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0007517"(muscle organ development)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036000|interpro:IPR036961|mint:P11055|reactome:R-HSA-390522|interpro:IPR000048(IQ calmodulin-binding region)|genbank_protein_gi:98986452(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:3i0087p2Hd15WKkAZspyWd6L7qc9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:546351CD8964BCC4|rigid:Pp4vLXcOk9fjl0tjV5fLgGUScqM	false	sufficient binding region:1632-1940..1940	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:P12883	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-519141|uniprotkb:Q14836|uniprotkb:Q14837|uniprotkb:Q14904|uniprotkb:Q16579|uniprotkb:Q2M1Y6|uniprotkb:Q92679|uniprotkb:Q9H1D5|ensembl:ENSP00000347507|uniprotkb:Q9UMM8|uniprotkb:A2TDB6|uniprotkb:B6D424|uniprotkb:Q9UDA2	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:myh7_human(display_long)|uniprotkb:Myosin heavy chain 7(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle beta isoform(gene name synonym)|uniprotkb:Myosin heavy chain slow isoform(gene name synonym)|uniprotkb:MYH7(gene name)|psi-mi:MYH7(display_short)|uniprotkb:MYHCB(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5666996|imex:IM-16425-844	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	ensembl:ENSG00000092054(gene)|ensembl:ENST00000355349(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031449"(regulation of slow-twitch skeletal muscle fiber contraction)|go:"GO:0032982"(myosin filament)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P12883|rcsb pdb:1IK2|rcsb pdb:2FXM|rcsb pdb:2FXO|rcsb pdb:3DTP|rcsb pdb:4DB1|rcsb pdb:4P7H|rcsb pdb:4PA0|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA4|rcsb pdb:4XA6|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ1|rcsb pdb:5CJ4|rcsb pdb:5TBY|rcsb pdb:5WJ7|rcsb pdb:5WJB|rcsb pdb:5WLQ|rcsb pdb:5WLZ|rcsb pdb:5WME|rcsb pdb:6PF2|rcsb pdb:6PFP|refseq:NP_000248.2|refseq:XP_016876829.1|genbank_protein_gi:115496168(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:Fz6cO12gihAyDMe06hLrQbrupbs9606	intact-crc:724F10EB9520D935|rigid:JqiP7kmopfP8dS6YvcxSlqbIJBE	false	sufficient binding region:1-442	sufficient binding region:1433-1935(IPR002928)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IUG5	uniprotkb:O75386	intact:EBI-1754049|uniprotkb:B2RWP3|uniprotkb:Q8NDI8|uniprotkb:Q8TE65|uniprotkb:Q8WWS0|uniprotkb:Q96KH2|uniprotkb:Q96KR8|uniprotkb:Q96KR9|intact:EBI-28967269|ensembl:ENSP00000334563|ensembl:ENSP00000441229|uniprotkb:F5GYU7|uniprotkb:A0A075B6F5|uniprotkb:F5GXR6	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:my18b_human(display_long)|uniprotkb:MYO18B(gene name)|psi-mi:MYO18B(display_short)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667014|imex:IM-16425-845	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000334563|ensembl:ENST00000407587|ensembl:ENSP00000386096|ensembl:ENSP00000441229|refseq:NP_115997.5|refseq:NP_001305174.1|ensembl:ENSG00000133454(gene)|ensembl:ENST00000335473(transcript)|ensembl:ENST00000536101(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030018"(Z disc)|go:"GO:0031941"(filamentous actin)|go:"GO:0055013"(cardiac muscle cell development)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR027417|interpro:IPR028561|interpro:IPR036064|interpro:IPR036961|genbank_protein_gi:51317365(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:LCxnp9wS7uqv6avEdThpucmxwsM9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:DCF01F5EF0413345|rigid:FCWMsZ9nuAsCiIRK9XeQPeCSGGU	false	sufficient binding region:1816-2567	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IUG5	uniprotkb:O75386	intact:EBI-1754049|uniprotkb:B2RWP3|uniprotkb:Q8NDI8|uniprotkb:Q8TE65|uniprotkb:Q8WWS0|uniprotkb:Q96KH2|uniprotkb:Q96KR8|uniprotkb:Q96KR9|intact:EBI-28967269|ensembl:ENSP00000334563|ensembl:ENSP00000441229|uniprotkb:F5GYU7|uniprotkb:A0A075B6F5|uniprotkb:F5GXR6	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:my18b_human(display_long)|uniprotkb:MYO18B(gene name)|psi-mi:MYO18B(display_short)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667031|imex:IM-16425-846	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000334563|ensembl:ENST00000407587|ensembl:ENSP00000386096|ensembl:ENSP00000441229|refseq:NP_115997.5|refseq:NP_001305174.1|ensembl:ENSG00000133454(gene)|ensembl:ENST00000335473(transcript)|ensembl:ENST00000536101(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030018"(Z disc)|go:"GO:0031941"(filamentous actin)|go:"GO:0055013"(cardiac muscle cell development)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR027417|interpro:IPR028561|interpro:IPR036064|interpro:IPR036961|genbank_protein_gi:51317365(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:LCxnp9wS7uqv6avEdThpucmxwsM9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:7BA1B70EAAB87C89|rigid:FCWMsZ9nuAsCiIRK9XeQPeCSGGU	false	sufficient binding region:1992-2567	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:O75376	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|ensembl:ENSP00000268712|uniprotkb:B3DLF8	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667048|imex:IM-16425-847	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	dip:DIP-29402N|ensembl:ENSP00000268712|ensembl:ENST00000395848|ensembl:ENSP00000379189|ensembl:ENST00000395851|ensembl:ENSP00000379192|ensembl:ENSG00000141027(gene)|ensembl:ENST00000268712(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|rcsb pdb:3H52|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:XP_011522388.1|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1|genbank_protein_gi:22538460(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606	intact-crc:6D605D2D61C1E22A|rigid:1zlpk/o0mE6s7bwDKcXEQQecm5Q	false	sufficient binding region:1-442	sufficient binding region:104-2440	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:P20929-4	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-9531519|ensembl:ENSP00000386259	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:p20929-4(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667065|imex:IM-16425-848	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	ensembl:ENSG00000183091(gene)|ensembl:ENST00000409198(transcript)|intact:EBI-1049657(isoform-parent)|genbank_protein_gi:115527119(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:aoHCLWV+j7ubdhBsylj1KjSUzwA9606	intact-crc:CF3B72A9610B911C|rigid:lTViymsUMe6oJrza5h/VfVLS0UM	false	sufficient binding region:1-442	sufficient binding region:1040-6669(IPR000900)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q14494	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-2804436|intact:EBI-28976146|ensembl:ENSP00000354855|uniprotkb:Q96FN6|uniprotkb:Q12877|uniprotkb:D3DTU3|uniprotkb:D3DTU5	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:nf2l1_human(display_long)|uniprotkb:HBZ17(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:TCF11(gene name synonym)|uniprotkb:Locus control region-factor 1(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 1(gene name synonym)|uniprotkb:Transcription factor 11(gene name synonym)|uniprotkb:NFE2L1(gene name)|psi-mi:NFE2L1(display_short)|uniprotkb:Nuclear factor erythroid 2-related factor 1(gene name synonym)|uniprotkb:Protein NRF1, p120 form(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667083|imex:IM-16425-849	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	ensembl:ENST00000357480|ensembl:ENSP00000350072|ensembl:ENSP00000354855|ensembl:ENST00000585291|ensembl:ENSP00000461960|ensembl:ENSG00000082641(gene)|ensembl:ENST00000362042(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:1901329"(regulation of odontoblast differentiation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029847|refseq:NP_003195.1|refseq:XP_005257467.1|refseq:XP_005257469.1|refseq:NP_001317191.1|genbank_protein_gi:4505378(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:/mXRFWPHxGFlrQmbhG3eDz9uXoc9606	intact-crc:931081AEE5E9BC2E|rigid:agULyMqjI5SgAyFcjol7YnA9Qqk	false	sufficient binding region:1-442	sufficient binding region:466-772..772	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IVI9	uniprotkb:O75386	intact:EBI-1391643|uniprotkb:Q27HG3|uniprotkb:Q53S62|uniprotkb:Q96CJ9|uniprotkb:A8K2I9|uniprotkb:B3KSF5|uniprotkb:E7EPT9|ensembl:ENSP00000318921	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:nostn_human(display_long)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Nitric oxide synthase traffic inducer(gene name synonym)|uniprotkb:BM247 homolog(gene name synonym)|uniprotkb:NOSTRIN(gene name)|psi-mi:NOSTRIN(display_short)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667100|imex:IM-16425-850	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001034813.2|refseq:NP_001165102.1|refseq:NP_001165103.1|refseq:NP_443178.2|ensembl:ENSG00000163072(gene)|ensembl:ENST00000317647(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028535|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|interpro:IPR036274|mint:Q8IVI9|rcsb pdb:2YUN|reactome:R-HSA-203641|genbank_protein_gi:89886446(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:995orjHO0YRgvNcLMP1kX2qC25s9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:A46802E9457C3833|rigid:5huW77MuZZ1NaFEOK6MxjHiKhz8	false	sufficient binding region:6-506	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:P48552	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667117|imex:IM-16425-851	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N|genbank_protein_gi:57232745(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606	intact-crc:51BA7E74879F9968|rigid:M0M1dWzmJECuJzm8ZDml6dxYPWU	false	sufficient binding region:1-442	sufficient binding region:185-1158	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q8N7H5	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667134|imex:IM-16425-852	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N|genbank_protein_gi:42476168(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606	intact-crc:C7CD330B34373661|rigid:gxIE6ZUC7EEdmlBT+P+v6t+s3q0	false	sufficient binding region:1-442	sufficient binding region:111-531	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q9BYE7	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667151|imex:IM-16425-853	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|genbank_protein_gi:58761529(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606	intact-crc:9514D35DFB361CC9|rigid:SYbPo6efSOehJa6vPCldNXxTU/A	false	sufficient binding region:1-442	sufficient binding region:58-350..350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q5VU43	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667168|imex:IM-16425-854	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|genbank_protein_gi:50658072(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2018/04/06	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	intact-crc:7BC88FD9F2C9C8DB|rigid:Q5VugBQAkUQ++DVUIFQoz/JDTr0	false	sufficient binding region:1-442	sufficient binding region:2117-2346	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q9H814	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-5667190|uniprotkb:Q9H8W1|ensembl:ENSP00000297540	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:phax_human(display_long)|uniprotkb:RNA U small nuclear RNA export adapter protein(gene name synonym)|uniprotkb:RNUXA(gene name synonym)|uniprotkb:PHAX(gene name)|psi-mi:PHAX(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667185|imex:IM-16425-855	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_115553.2|rcsb pdb:2XC7|reactome:R-HSA-191859|reactome:R-HSA-6807505|ensembl:ENSG00000164902(gene)|ensembl:ENST00000297540(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0015031"(protein transport)|go:"GO:0015643"(toxic substance binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043489"(RNA stabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019385|interpro:IPR038092|interpro:IPR039047|mint:Q9H814|genbank_protein_gi:66392145(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:5cyoxIMxtl/gBViCRP3lTsoH/RU9606	intact-crc:0F5BD2E0A564879B|rigid:xWJwiU5i5WdqrDGmdQ/0j7gyvuw	false	sufficient binding region:1-442	sufficient binding region:6-394	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10644	uniprotkb:O75386	intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667207|imex:IM-16425-856	author score:E|author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY|genbank_protein_gi:47132580(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:3624FB2513891244|rigid:GOerSVctVbvEZFNJtAsYcbBNYMs	false	sufficient binding region:1-381	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q9P2K3	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-743428|uniprotkb:B3KYA2|uniprotkb:B4DYY7|uniprotkb:Q5VT47|uniprotkb:Q7L9I5|uniprotkb:Q8N5U3|uniprotkb:Q9NV83|ensembl:ENSP00000355972	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:rcor3_human(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667224|imex:IM-16425-857	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	rcsb pdb:4CZZ|refseq:NP_001129695.1|refseq:NP_001129696.2|refseq:NP_001129697.1|refseq:NP_060724.1|ensembl:ENSG00000117625(gene)|ensembl:ENST00000367005(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9P2K3|genbank_protein_gi:33620752(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:hzuKCK7o/85XbN65z8Ua+XNaSJc9606	intact-crc:06572627DE662970|rigid:1TX2m1VOrnOZBDMdGc6kN+3ZyIM	false	sufficient binding region:1-442	sufficient binding region:1-495(IPR000949)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:O14730	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-1047061|uniprotkb:Q8IXN9|ensembl:ENSP00000341874	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:riok3_human(display_long)|uniprotkb:sudD homolog(gene name synonym)|uniprotkb:RIOK3(gene name)|psi-mi:RIOK3(display_short)|uniprotkb:SUDD(gene name synonym)|uniprotkb:RIO kinase 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667242|imex:IM-16425-858	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_003822.2|ensembl:ENSG00000101782(gene)|ensembl:ENST00000339486(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0089720"(caspase binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990786"(cellular response to dsDNA)|interpro:IPR000687(RIO kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017406(Serine/threonine-protein kinase Rio3)|interpro:IPR018935|reactome:R-HSA-6791226|genbank_protein_gi:22325376(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:pC/TdpTG0HK/d1F4KIIpU3bzTcg9606	intact-crc:D20159C0347E8FD3|rigid:fpwJ3I/Oo0YrjLA90mKVYwxLwfo	false	sufficient binding region:1-442	sufficient binding region:1-519	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5U6	uniprotkb:O75386	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667259|imex:IM-16425-859	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6|genbank_protein_gi:156630998(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:EF502CE8AE4E936D|rigid:Ooq8XehBmpi+urrZJZqpfrEDARo	false	sufficient binding region:47-811	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:P21817	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-1221290|uniprotkb:Q16314|uniprotkb:Q16368|uniprotkb:Q9NPK1|uniprotkb:Q9P1U4|ensembl:ENSP00000352608	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:ryr1_human(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:RYDR(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667276|imex:IM-16425-860	author score:B|author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_000531.2|refseq:NP_001036188.1|dip:DIP-29708N|ensembl:ENSG00000196218(gene)|ensembl:ENST00000359596(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031674"(I band)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:6UHI|rcsb pdb:6UHS|reactome:R-HSA-2672351|reactome:R-HSA-5578775|genbank_protein_gi:113204616(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:WHlPtd5++5f+9GX0IGshsqJCOTg9606	intact-crc:E32E52B64510017B|rigid:w9ydab9QzKpelb/1TKRqpcwa5Fg	false	sufficient binding region:1-442	sufficient binding region:1833-5038	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q9P270	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-3959887|uniprotkb:A8K4P1|uniprotkb:Q8N5R3|ensembl:ENSP00000264313	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:slai2_human(display_long)|uniprotkb:SLAIN2(gene name)|psi-mi:SLAIN2(display_short)|uniprotkb:KIAA1458(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667293|imex:IM-16425-861	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_065897.1|ensembl:ENSG00000109171(gene)|ensembl:ENST00000264313(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR026179|mint:Q9P270|rcsb pdb:3RDV|genbank_protein_gi:113416081(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:r8OlU6BASEpehSYkbA9b3F3q5go9606	intact-crc:8E38714F56550038|rigid:NTgXL0P3vV7NC22RRolwcMWsVb0	false	sufficient binding region:1-442	sufficient binding region:259-581..581	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:P11277	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667310|imex:IM-16425-862	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|genbank_protein_gi:67782318(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606	intact-crc:C84F3304E238681E|rigid:krHT55F3Cu1lRiQH1YppjJoIXAA	false	sufficient binding region:1-442	sufficient binding region:254-2137(IPR001715)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:P11277	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667329|imex:IM-16425-863	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|genbank_protein_gi:67782318(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606	intact-crc:6120A2EB89B1AD01|rigid:krHT55F3Cu1lRiQH1YppjJoIXAA	false	sufficient binding region:1-442	sufficient binding region:1675-2137(IPR002017)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:O76094	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-1058850|ensembl:ENSP00000495128|intact:EBI-2654733|uniprotkb:G5E9Z8|uniprotkb:Q7Z3C0	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:srp72_human(display_long)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667347|imex:IM-16425-864	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_008878.3|refseq:NP_001254651.1|ensembl:ENSG00000174780(gene)|ensembl:ENST00000642900(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR019734|interpro:IPR026270|interpro:IPR031545|mint:O76094|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:5WRW|rcsb pdb:7NFX|reactome:R-HSA-1799339|genbank_protein_gi:109638748(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:NJfyOcmKiBWszQsH0EQotsdwhU09606	intact-crc:57684190A215920A|rigid:2aMCPCWUoj3JyYaJRMB7SgU9+RU	false	sufficient binding region:1-442	sufficient binding region:71-671(IPR001440)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:P13805	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-726527|uniprotkb:O95472|uniprotkb:Q16061|uniprotkb:Q5U0E1|ensembl:ENSP00000467176	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:tnnt1_human(display_long)|uniprotkb:Slow skeletal muscle troponin T(gene name synonym)|uniprotkb:TNNT1(gene name)|psi-mi:TNNT1(display_short)|uniprotkb:TNT(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667365|imex:IM-16425-865	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_001278703.1|refseq:NP_001119604.1|refseq:NP_001119605.1|refseq:NP_003274.3|refseq:XP_016882675.1|ensembl:ENSG00000105048(gene)|ensembl:ENST00000588981(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005861"(troponin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0031014"(troponin T binding)|go:"GO:0031444"(slow-twitch skeletal muscle fiber contraction)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045932"(negative regulation of muscle contraction)|interpro:IPR001978(Troponin)|interpro:IPR027707|interpro:IPR038077|mint:P13805|reactome:R-HSA-390522|genbank_protein_gi:21706666(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:zYApSOt95yJcjJZHRMuHR9C5Kqw9606	intact-crc:4AF01EF89513AA14|rigid:mvgb14watsFZrt94CDB4iBr2/ss	false	sufficient binding region:1-442	sufficient binding region:103-278	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:P45378	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-714264|uniprotkb:A8MQ76|uniprotkb:A8MSW1|uniprotkb:Q17RG9|uniprotkb:Q6FH29|uniprotkb:Q6N056|uniprotkb:Q12975|uniprotkb:Q12976|uniprotkb:Q12977|uniprotkb:Q12978|uniprotkb:Q86TH6|uniprotkb:B3KPX3|uniprotkb:B7WP64|uniprotkb:B7ZL26|uniprotkb:B7ZVV9|ensembl:ENSP00000380468|ensembl:ENSP00000500796	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:tnnt3_human(display_long)|uniprotkb:Fast skeletal muscle troponin T(gene name synonym)|uniprotkb:Beta-TnTF(gene name synonym)|uniprotkb:TNNT3(gene name)|psi-mi:TNNT3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667382|imex:IM-16425-866	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_001036245.1|refseq:NP_001036246.1|refseq:NP_001036247.1|refseq:NP_006748.1|refseq:XP_006718353.1|refseq:XP_006718356.1|refseq:XP_006718363.1|refseq:NP_001284575.1|refseq:XP_016873695.1|refseq:XP_011518645.1|ensembl:ENSG00000130595(gene)|ensembl:ENSG00000288250(gene)|ensembl:ENST00000397301(transcript)|ensembl:ENST00000673082(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005861"(troponin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0030172"(troponin C binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:1903612"(positive regulation of calcium-dependent ATPase activity)|interpro:IPR001978(Troponin)|interpro:IPR027707|interpro:IPR027708|interpro:IPR038077|reactome:R-HSA-390522|genbank_protein_gi:112789540(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:aj91rEv9nNfxiOXvbn/fcCLyNjs9606	intact-crc:08DD8B8B44105DF9|rigid:qxG3FAqr9LtI+kj1eAsDI9oIjR8	false	sufficient binding region:1-442	sufficient binding region:40-269	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H4A3	uniprotkb:O75386	intact:EBI-457907|uniprotkb:O15052|uniprotkb:P54963|uniprotkb:Q86WL5|uniprotkb:Q8N673|uniprotkb:Q9P1S9|uniprotkb:Q4VBX9|intact:EBI-948424|uniprotkb:A1L4B0|uniprotkb:Q6IFS5|uniprotkb:C5HTZ5|uniprotkb:C5HTZ6|uniprotkb:C5HTZ7|uniprotkb:H6WZW3|uniprotkb:Q96CZ6|ensembl:ENSP00000313059	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:wnk1_human(display_long)|uniprotkb:WNK1(gene name)|psi-mi:WNK1(display_short)|uniprotkb:KDP(gene name synonym)|uniprotkb:KIAA0344(gene name synonym)|uniprotkb:PRKWNK1(gene name synonym)|uniprotkb:Protein kinase with no lysine 1(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 1(gene name synonym)|uniprotkb:Erythrocyte 65 kDa protein(gene name synonym)|uniprotkb:Kinase deficient protein(gene name synonym)|uniprotkb:HSN2(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667399|imex:IM-16425-867	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000313059|ensembl:ENST00000340908|ensembl:ENSP00000341292|ensembl:ENST00000530271|ensembl:ENSP00000433548|ensembl:ENST00000537687|ensembl:ENSP00000444465|ensembl:ENST00000675631|ensembl:ENSP00000502415|refseq:NP_001171914.1|refseq:NP_055638.2|refseq:NP_061852.3|refseq:NP_998820.3|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1904062"(regulation of cation transmembrane transport)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|mint:Q9H4A3|rcsb pdb:4PWN|rcsb pdb:5TF9|rcsb pdb:5WDY|rcsb pdb:5WE8|rcsb pdb:6FBK|reactome:R-HSA-2672351|go:"GO:0097022"(lymphocyte migration into lymph node)|ensembl:ENSG00000060237(gene)|ensembl:ENST00000315939(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006811"(ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033633"(negative regulation of cell-cell adhesion mediated by integrin)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038116"("chemokine (C-C motif) ligand 21 signaling pathway")|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048666"(neuron development)|go:"GO:0050794"(regulation of cellular process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|refseq:XP_016875326.1|refseq:XP_016875327.1|dip:DIP-32648N|genbank_protein_gi:12711659(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Jt4cvhSumyRRIZDmWgj4GsG7wjQ9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:29DAB5C3623A3F1F|rigid:s+gbGUXdtBL2O258heA1NvDgmq0	false	sufficient binding region:1104-2382	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P243	uniprotkb:O75386	intact:EBI-3943507|uniprotkb:Q3MIM5|uniprotkb:Q75PJ7|uniprotkb:Q6PJ01|uniprotkb:Q75PJ6|uniprotkb:Q75PJ9|uniprotkb:Q86X64|ensembl:ENSP00000367069|uniprotkb:B7ZL15|uniprotkb:E9PER3	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:zfat_human(display_long)|uniprotkb:ZFAT(gene name)|psi-mi:ZFAT(display_short)|uniprotkb:KIAA1485(gene name synonym)|uniprotkb:ZFAT1(gene name synonym)|uniprotkb:ZNF406(gene name synonym)|uniprotkb:Zinc finger gene in AITD susceptibility region(gene name synonym)|uniprotkb:Zinc finger protein 406(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667416|imex:IM-16425-868	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011515505.1|ensembl:ENSG00000066827(gene)|ensembl:ENST00000377838(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060712"(spongiotrophoblast layer development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2ELM|rcsb pdb:2ELN|rcsb pdb:2ELO|rcsb pdb:2ELP|rcsb pdb:2ELQ|rcsb pdb:2ELR|rcsb pdb:2ELS|rcsb pdb:2ELT|rcsb pdb:2ELU|rcsb pdb:2ELV|rcsb pdb:2RSH|rcsb pdb:2RSI|rcsb pdb:2RSJ|rcsb pdb:2RUT|rcsb pdb:2RUU|rcsb pdb:2RUV|rcsb pdb:2RUW|rcsb pdb:2RUX|rcsb pdb:2RUY|rcsb pdb:2RUZ|rcsb pdb:2RV0|rcsb pdb:2RV1|rcsb pdb:2RV2|rcsb pdb:2RV3|rcsb pdb:2RV6|rcsb pdb:2RV7|refseq:NP_001025110.2|refseq:NP_065914.2|refseq:NP_001167628.1|refseq:NP_001276323.1|genbank_protein_gi:71480168(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:MFTu5hiuxSVrIjbOofRPLLhiumQ9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:7CC7F59379227A6E|rigid:zUKn8uQqu8iQcz5o3gfxbPu69Yc	false	sufficient binding region:37-1243	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCG1	uniprotkb:O75386	intact:EBI-2857453|intact:EBI-3922135|uniprotkb:Q14589|uniprotkb:Q504Q8|uniprotkb:Q96JC5|uniprotkb:Q9BVY9|uniprotkb:Q9H7N6|ensembl:ENSP00000406201|ensembl:ENSP00000409597|ensembl:ENSP00000470961|ensembl:ENSP00000507845	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:zn160_human(display_long)|uniprotkb:ZNF160(gene name)|psi-mi:ZNF160(display_short)|uniprotkb:KIAA1611(gene name synonym)|uniprotkb:Zinc finger protein HZF5(gene name synonym)|uniprotkb:Zinc finger protein Kr18(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667433|imex:IM-16425-869	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001309055.1|refseq:NP_001096073.1|refseq:NP_150630.2|refseq:NP_942596.1|refseq:NP_001309057.1|refseq:NP_001309058.1|refseq:NP_001309059.1|refseq:NP_001309060.1|refseq:NP_001309061.1|refseq:NP_001309062.1|refseq:NP_001309063.1|refseq:NP_001309064.1|refseq:NP_001309065.1|refseq:XP_016882935.1|refseq:XP_016882937.1|refseq:NP_001309054.1|ensembl:ENSG00000170949(gene)|ensembl:ENST00000418871(transcript)|ensembl:ENST00000429604(transcript)|ensembl:ENST00000599056(transcript)|ensembl:ENST00000683776(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030097"(hemopoiesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|genbank_protein_gi:38788301(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:Q2G1Ettvdkbgz8bHt2bmZzOPRjg9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:15796DFF0BCCC0B7|rigid:BIV/tHi8aKeZkK4eZVq0BXRWWWI	false	sufficient binding region:115-818	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96JM2	uniprotkb:O75386	intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667450|imex:IM-16425-870	author score:C|author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|genbank_protein_gi:114431235(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:AADEDB7C4D8FB505|rigid:FHosC+5SRLbWh/JtKdIb/8S3tFw	false	sufficient binding region:2188-2506(IPR007087)	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N2I2	uniprotkb:O75386	intact:EBI-5667468|uniprotkb:B4E271|uniprotkb:C9JRN5|uniprotkb:D4PHA2|uniprotkb:E9PCD9|ensembl:ENSP00000322529	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:zn619_human(display_long)|uniprotkb:ZNF619(gene name)|psi-mi:ZNF619(display_short)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667472|imex:IM-16425-871	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001138554.1|refseq:NP_001138565.1|refseq:NP_001138555.1|ensembl:ENSG00000177873(gene)|ensembl:ENST00000314686(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|genbank_protein_gi:27734906(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:wq3faSIykWHK9gGqN5raIZFuSM49606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:DDBAE1AE32294821|rigid:4ljjX3D61CxKmCxH2TeUuCAQhsU	false	sufficient binding region:128-560	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZN11	uniprotkb:O75386	intact:EBI-5667494|ensembl:ENSP00000396402|ensembl:ENSP00000468605|ensembl:ENSP00000487183|uniprotkb:Q7Z3Q9|uniprotkb:E9PGN4	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	psi-mi:zn793_human(display_long)|uniprotkb:ZNF793(gene name)|psi-mi:ZNF793(display_short)	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667489|imex:IM-16425-872	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188227(gene)|ensembl:ENST00000445217(transcript)|ensembl:ENST00000587143(transcript)|refseq:NP_001013681.2|refseq:XP_005258984.1|refseq:XP_006723276.1|ensembl:ENST00000627814(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q6ZN11|reactome:R-HSA-212436|genbank_protein_gi:61966772(identity)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:mqRXXZG0Kd/Cj7o0qCdZD8C7i4A9606	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	intact-crc:A15E87684EAEE865|rigid:u/22QI9vMWQFYRClw+3iSXW15fU	false	sufficient binding region:93-406	sufficient binding region:1-442	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q9Y2P0	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-5667516|uniprotkb:B7Z5Y0|uniprotkb:G3V1S0|ensembl:ENSP00000444747	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:zn835_human(display_long)|uniprotkb:ZNF835(gene name)|psi-mi:ZNF835(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667511|imex:IM-16425-873	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:NP_001005850.2|refseq:XP_005259439.1|refseq:XP_005259440.1|ensembl:ENSG00000127903(gene)|ensembl:ENST00000537055(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|genbank_protein_gi:54291709(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:b/JKwoa7JDbzUqtqueu3IXW56kM9606	intact-crc:AE53919DDE910B06|rigid:xNpkgCGEUlm/G1KJAzVPyXMkVCg	false	sufficient binding region:1-442	sufficient binding region:6-537	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75386	uniprotkb:Q3MJ62	intact:EBI-5357290|uniprotkb:B3KNB7|uniprotkb:D3DUQ4|uniprotkb:Q8N5B0|uniprotkb:B7Z6A2|uniprotkb:F8WBZ9|intact:EBI-28988689|ensembl:ENSP00000410051	intact:EBI-5667532|uniprotkb:Q96KV9|ensembl:ENSP00000289788	psi-mi:tulp3_human(display_long)|uniprotkb:TULP3(gene name)|psi-mi:TULP3(display_short)|uniprotkb:TUBL3(gene name synonym)|uniprotkb:Tubby-like protein 3(gene name synonym)	psi-mi:zsc23_human(display_long)|uniprotkb:ZNF390(gene name synonym)|uniprotkb:ZNF453(gene name synonym)|uniprotkb:Zinc finger protein 390(gene name synonym)|uniprotkb:Zinc finger protein 453(gene name synonym)|uniprotkb:ZSCAN23(gene name)|psi-mi:ZSCAN23(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667537|imex:IM-16425-874	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153880.1|refseq:NP_003315.2|ensembl:ENST00000397132|ensembl:ENSP00000380321|ensembl:ENSP00000410051|ensembl:ENST00000540184|ensembl:ENSP00000444110|ensembl:ENSG00000078246(gene)|ensembl:ENST00000448120(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019899"(enzyme binding)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060434"(bronchus morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061548"(ganglion development)|go:"GO:0097546"(ciliary base)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000007(Tubby, C-terminal)|interpro:IPR005398(Tubby, N-terminal)|interpro:IPR018066|interpro:IPR025659|reactome:R-HSA-5610787|genbank_protein_gi:42544229(identity)	refseq:XP_016865968.1|refseq:XP_011512708.1|refseq:XP_011512710.1|refseq:XP_011512712.1|refseq:NP_001012458.1|refseq:XP_005249007.1|ensembl:ENSG00000187987(gene)|ensembl:ENST00000289788(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|genbank_protein_gi:75516580(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:zfk5c5/u3lyjIQfvJWtmZeee0SI9606	rogid:wyzpqrDoEXGXrYbvyVZwIYw4NwI9606	intact-crc:33B80A9EF8658A25|rigid:TNF4JvRR83xP3grEv4iYRycBeaI	false	sufficient binding region:1-442	sufficient binding region:168-389..389	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:Q96J02	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-1564678|uniprotkb:O43584|uniprotkb:Q5TEL0|uniprotkb:Q96F66|uniprotkb:Q9BY75|uniprotkb:Q9H451|uniprotkb:Q9H4U5|uniprotkb:A6NEW4|uniprotkb:Q5QP37|uniprotkb:E1P5P3|uniprotkb:B4E234|uniprotkb:F5H217|ensembl:ENSP00000262650|ensembl:ENSP00000499786	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:itch_human(display_long)|uniprotkb:HECT-type E3 ubiquitin transferase Itchy homolog(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 4(gene name synonym)|uniprotkb:NFE2-associated polypeptide 1(gene name synonym)|uniprotkb:ITCH(gene name)|psi-mi:ITCH(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667554|imex:IM-16425-875	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|genbank_protein_gi:33946268(identity)	refseq:NP_001311126.1|refseq:NP_113671.3|refseq:NP_001244066.1|refseq:NP_001311127.1|refseq:NP_001244067.1|refseq:XP_016883578.1|refseq:XP_016883580.1|dip:DIP-29849N|ensembl:ENSG00000078747(gene)|ensembl:ENST00000262650(transcript)|ensembl:ENST00000665346(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045236"(CXCR chemokine receptor binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090085"(regulation of protein deubiquitination)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:Q96J02|rcsb pdb:2DMV|rcsb pdb:2KYK|rcsb pdb:2NQ3|rcsb pdb:2P4R|rcsb pdb:2YSF|rcsb pdb:3TUG|rcsb pdb:4ROF|rcsb pdb:5C7M|rcsb pdb:5CQ2|rcsb pdb:5DWS|rcsb pdb:5DZD|rcsb pdb:5SXP|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-2122948|reactome:R-HSA-5610780|reactome:R-HSA-5632684|reactome:R-HSA-8939236|reactome:R-HSA-936440|reactome:R-HSA-983168|genbank_protein_gi:27477108(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:JyySOfI+ZHOI1mvdxWDGN6njgCY9606	intact-crc:BF7F9407FE3838D1|rigid:3zAFPiXYqxI/Oi+Bm3yFpxRuPEY	false	sufficient binding region:1-405	sufficient binding region:271-903(IPR001202)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:P45378	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-714264|uniprotkb:A8MQ76|uniprotkb:A8MSW1|uniprotkb:Q17RG9|uniprotkb:Q6FH29|uniprotkb:Q6N056|uniprotkb:Q12975|uniprotkb:Q12976|uniprotkb:Q12977|uniprotkb:Q12978|uniprotkb:Q86TH6|uniprotkb:B3KPX3|uniprotkb:B7WP64|uniprotkb:B7ZL26|uniprotkb:B7ZVV9|ensembl:ENSP00000380468|ensembl:ENSP00000500796	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:tnnt3_human(display_long)|uniprotkb:Fast skeletal muscle troponin T(gene name synonym)|uniprotkb:Beta-TnTF(gene name synonym)|uniprotkb:TNNT3(gene name)|psi-mi:TNNT3(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667572|imex:IM-16425-876	author score:D|author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|genbank_protein_gi:33946268(identity)	refseq:NP_001036245.1|refseq:NP_001036246.1|refseq:NP_001036247.1|refseq:NP_006748.1|refseq:XP_006718353.1|refseq:XP_006718356.1|refseq:XP_006718363.1|refseq:NP_001284575.1|refseq:XP_016873695.1|refseq:XP_011518645.1|ensembl:ENSG00000130595(gene)|ensembl:ENSG00000288250(gene)|ensembl:ENST00000397301(transcript)|ensembl:ENST00000673082(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005861"(troponin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0030172"(troponin C binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:1903612"(positive regulation of calcium-dependent ATPase activity)|interpro:IPR001978(Troponin)|interpro:IPR027707|interpro:IPR027708|interpro:IPR038077|reactome:R-HSA-390522|genbank_protein_gi:112789540(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:aj91rEv9nNfxiOXvbn/fcCLyNjs9606	intact-crc:2586C74D85154302|rigid:xso7QeNqUqxdUjICAo93IIcs4Y0	false	sufficient binding region:1-405	sufficient binding region:1-269	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43516	uniprotkb:O00401	intact:EBI-346356|uniprotkb:Q15220|uniprotkb:Q6MZU9|uniprotkb:Q9BU37|uniprotkb:Q9UNP1|uniprotkb:Q53TA9|uniprotkb:B8ZZM1|uniprotkb:D3DPE4|ensembl:ENSP00000352802|ensembl:ENSP00000376329|ensembl:ENSP00000376330|ensembl:ENSP00000503603	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	psi-mi:wipf1_human(display_long)|uniprotkb:WIPF1(gene name)|psi-mi:WIPF1(display_short)|uniprotkb:WIP(gene name synonym)|uniprotkb:Wiskott-Aldrich syndrome protein-interacting protein(gene name synonym)|uniprotkb:Protein PRPL-2(gene name synonym)|uniprotkb:WASPIP(gene name synonym)	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667589|imex:IM-16425-877	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070737.1|refseq:NP_003378.3|refseq:XP_011510082.1|ensembl:ENST00000272746|ensembl:ENSP00000272746|ensembl:ENSP00000352802|ensembl:ENSP00000376329|ensembl:ENSP00000376330|ensembl:ENST00000409891|ensembl:ENSP00000386431|ensembl:ENSP00000503603|dip:DIP-17015N|ensembl:ENSG00000115935(gene)|ensembl:ENST00000359761(transcript)|ensembl:ENST00000392546(transcript)|ensembl:ENST00000392547(transcript)|ensembl:ENST00000679041(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028295|mint:O43516|rcsb pdb:2A41|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9664422|genbank_protein_gi:116284399(identity)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|genbank_protein_gi:33946268(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:8qaxT2n0EXIVTi08xHsryCSSt9k9606	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	intact-crc:8C19291F2EBB1C23|rigid:i5AqnBY6+GLdvjJ7O/6wbe3BUR8	false	sufficient binding region:433-503	sufficient binding region:1-405	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TF74	uniprotkb:O00401	intact:EBI-2850112|uniprotkb:Q8TE44|uniprotkb:A8K0L3|uniprotkb:Q658J8|uniprotkb:Q71RE1|ensembl:ENSP00000320924|ensembl:ENSP00000462350|ensembl:ENSP00000462826	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	psi-mi:wipf2_human(display_long)|uniprotkb:WIPF2(gene name)|psi-mi:WIPF2(display_short)|uniprotkb:WICH(gene name synonym)|uniprotkb:WIRE(gene name synonym)|uniprotkb:WASP-interacting protein-related protein(gene name synonym)|uniprotkb:WIP- and CR16-homologous protein(gene name synonym)|uniprotkb:WIP-related protein(gene name synonym)|uniprotkb:PP10631(orf name)	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667606|imex:IM-16425-878	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000320924|ensembl:ENSP00000462350|ensembl:ENSP00000462826|refseq:XP_011522715.1|refseq:NP_573571.1|refseq:XP_005257140.1|refseq:XP_005257141.1|ensembl:ENSG00000171475(gene)|ensembl:ENST00000323571(transcript)|ensembl:ENST00000583130(transcript)|ensembl:ENST00000585043(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0030048"(actin filament-based movement)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028294|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422|genbank_protein_gi:75812910(identity)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|genbank_protein_gi:33946268(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:xnXvZLySNsfyWjL2lkAMUH16hlU9606	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	intact-crc:32FC982FAFEFDBB6|rigid:pZXG6nr6A0dpzYa+mmtc8SH48vI	false	sufficient binding region:385-440	sufficient binding region:1-405	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:A6NGB9	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-3959572|ensembl:ENSP00000242140|uniprotkb:B8ZZV2	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:wipf3_human(display_long)|uniprotkb:WIPF3(gene name)|psi-mi:WIPF3(display_short)|uniprotkb:CR16(gene name synonym)|uniprotkb:Corticosteroids and regional expression protein 16 homolog(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667623|imex:IM-16425-879	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|genbank_protein_gi:33946268(identity)	ensembl:ENSG00000122574(gene)|ensembl:ENST00000242140(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030154"(cell differentiation)|interpro:IPR003124(Actin-binding WH2)|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9664422|refseq:NP_001073998.2|ensembl:ENSP00000242140|genbank_protein_gi:122937495(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:PZoIDCyy4/ywZBt/x/A344Fhons9606	intact-crc:FB547AED58BA3E04|rigid:XNmTiByq4Xc7+1AP9YV/AmEZhAQ	false	sufficient binding region:1-405	sufficient binding region:420-439	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H0M0	uniprotkb:O00401	intact:EBI-742157|uniprotkb:O00307|uniprotkb:Q96BP4|ensembl:ENSP00000265428|ensembl:ENSP00000427793|uniprotkb:Q5YLC1	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	psi-mi:wwp1_human(display_long)|uniprotkb:WWP1(gene name)|psi-mi:WWP1(display_short)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 5(gene name synonym)|uniprotkb:TGIF-interacting ubiquitin ligase 1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase WWP1(gene name synonym)	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667640|imex:IM-16425-880	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008944.1|interpro:IPR035892|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR035983|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR036020|mint:Q9H0M0|rcsb pdb:1ND7|rcsb pdb:2OP7|rcsb pdb:5HPS|rcsb pdb:5HPT|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|rcsb pdb:6J1X|rcsb pdb:6J1Y|reactome:R-HSA-1253288|reactome:R-HSA-2672351|reactome:R-HSA-8939902|reactome:R-HSA-983168|interpro:IPR024928|ensembl:ENSG00000123124(gene)|ensembl:ENST00000265428(transcript)|ensembl:ENST00000517970(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_005250817.1|genbank_protein_gi:33946331(identity)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|genbank_protein_gi:33946268(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:a+aRHHhwu3pCkmlkDNqcN1PJ7LI9606	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	intact-crc:E835352B6AC75A85|rigid:tRhzvu56pcYd0L9rtipAkL3X3bs	false	sufficient binding region:453-922(IPR001202)	sufficient binding region:1-405	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:Q9H0M0	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-742157|uniprotkb:O00307|uniprotkb:Q96BP4|ensembl:ENSP00000265428|ensembl:ENSP00000427793|uniprotkb:Q5YLC1	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:wwp1_human(display_long)|uniprotkb:WWP1(gene name)|psi-mi:WWP1(display_short)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 5(gene name synonym)|uniprotkb:TGIF-interacting ubiquitin ligase 1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase WWP1(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Blandin et al. (2013)	pubmed:23414517|imex:IM-16425	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5667658|imex:IM-16425-881	author score:A|author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|genbank_protein_gi:33946268(identity)	refseq:NP_008944.1|interpro:IPR035892|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR035983|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR036020|mint:Q9H0M0|rcsb pdb:1ND7|rcsb pdb:2OP7|rcsb pdb:5HPS|rcsb pdb:5HPT|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|rcsb pdb:6J1X|rcsb pdb:6J1Y|reactome:R-HSA-1253288|reactome:R-HSA-2672351|reactome:R-HSA-8939902|reactome:R-HSA-983168|interpro:IPR024928|ensembl:ENSG00000123124(gene)|ensembl:ENST00000265428(transcript)|ensembl:ENST00000517970(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_005250817.1|genbank_protein_gi:33946331(identity)	-	-	-	figure legend:Table S3 and S2|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/12/16	2014/10/16	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:a+aRHHhwu3pCkmlkDNqcN1PJ7LI9606	intact-crc:42DC7790FE5E8C32|rigid:tRhzvu56pcYd0L9rtipAkL3X3bs	false	sufficient binding region:1-405	sufficient binding region:341-922(IPR001202)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)