#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H2F3 uniprotkb:P09022 intact:EBI-3918847|ensembl:ENSP00000297679|uniprotkb:Q9BSN9|uniprotkb:Q96M28 intact:EBI-3957603|uniprotkb:P15463 psi-mi:3bhs7_human(display_long)|uniprotkb:HSD3B7(gene name)|psi-mi:HSD3B7(display_short)|uniprotkb:3 beta-hydroxysteroid dehydrogenase type VII(gene name synonym)|uniprotkb:"3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase"(gene name synonym)|uniprotkb:Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958062|imex:IM-15418-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099377(gene)|ensembl:ENST00000297679(transcript)|go:"GO:0003854"(3-beta-hydroxy-delta5-steroid dehydrogenase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0035754"(B cell chemotaxis)|go:"GO:0047016"(cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity)|interpro:IPR002225(3-beta hydroxysteroid dehydrogenase/isomerase)|interpro:IPR036291|reactome:R-HSA-193368|reactome:R-HSA-193775|reactome:R-HSA-193807|refseq:XP_011544262.1|refseq:XP_011544263.1|refseq:XP_011544264.1|refseq:NP_079469.2|refseq:NP_001136249.1|refseq:NP_001136250.1|refseq:XP_005255658.2|refseq:XP_016879221.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:bwogLTG31xasQpYzXeFK+g2pzQM9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:84FEBD7589EB998C|rigid:kml2yjdprjRh1YLLPzYotPfQke0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:P49639 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-740785|uniprotkb:O43363|uniprotkb:B2R8U7|uniprotkb:A4D184 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:hxa1_human(display_long)|uniprotkb:Homeobox protein Hox-1F(gene name synonym)|uniprotkb:HOXA1(gene name)|psi-mi:HOXA1(display_short)|uniprotkb:HOX1F(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958058|imex:IM-15418-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_005513.1|refseq:NP_705873.2|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|reactome:R-HSA-5617472|mint:P49639 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:QjQVU0uonSpj5vQU0pgzXuXmW3Y9606 intact-crc:D1114FA0EDCF8446|rigid:DI8lXIALke+tL4XULOfKvdXbXuc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60269 uniprotkb:P09022 intact:EBI-740397|uniprotkb:Q5SVF0|ensembl:ENSP00000363433|ensembl:ENSP00000363436 intact:EBI-3957603|uniprotkb:P15463 psi-mi:grin2_human(display_long)|uniprotkb:GPRIN2(gene name)|psi-mi:GPRIN2(display_short)|uniprotkb:KIAA0514(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957645|imex:IM-15418-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055511.2|ensembl:ENSG00000204175(gene)|ensembl:ENST00000374314(transcript)|ensembl:ENST00000374317(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0031175"(neuron projection development)|interpro:IPR026646|interpro:IPR032745|mint:O60269|refseq:XP_011538702.1|refseq:XP_005277723.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:DEZbDwZo783sIi7bAKh119g1NIg9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:5FFAAAE986BB8C6B|rigid:DnqCdfcGIoIN17dq3i/om9tWoTE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UY14 uniprotkb:P09022 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 intact:EBI-3957603|uniprotkb:P15463 psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957602|imex:IM-15418-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:470E404E3972AE32|rigid:o/xg+wr5ecYpgLNUx2n2fFZxP54 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9BSW2 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-739773|uniprotkb:B4E1X0|uniprotkb:B9EK63|ensembl:ENSP00000409382 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:efc4b_human(display_long)|uniprotkb:CRACR2A(gene name)|psi-mi:CRACR2A(display_short)|uniprotkb:Calcium release-activated calcium channel regulator 2A(gene name synonym)|uniprotkb:Calcium release-activated channel regulator 2A(gene name synonym)|uniprotkb:EFCAB4B(gene name synonym)|uniprotkb:RAB46(gene name synonym)|uniprotkb:Ras-related protein Rab-46(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957624|imex:IM-15418-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001138430.1|refseq:NP_116069.1|ensembl:ENSG00000130038(gene)|ensembl:ENST00000440314(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001772"(immunological synapse)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031982"(vesicle)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0034776"(response to histamine)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051928"(positive regulation of calcium ion transport)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:6PSD|reactome:R-HSA-6798695|interpro:IPR027417 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2021/04/12 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:IjhHTze6Dftzv9JltvNQgdATG+89606 intact-crc:E3A48754913D31DF|rigid:IEIDvypss8pGlp9+6hY5OkcNJ9I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q6P1W5 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957614|imex:IM-15418-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 intact-crc:F9A806347D998F67|rigid:JA6v6Nq+/PiH5MIpGCqvJ36GMts false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q8N5R6 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957619|imex:IM-15418-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606 intact-crc:8EB152A8FF474C3F|rigid:jDnxFGk7bcjFrScQznyKamOGjgA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IYX7 uniprotkb:P09022 intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58 intact:EBI-3957603|uniprotkb:P15463 psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957633|imex:IM-15418-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:7BFA020B84798778|rigid:MzOQaB/yKNHRVVYNRKGj9ShgCK4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JSZ5 uniprotkb:P09022 intact:EBI-744891|uniprotkb:Q66VZ2|uniprotkb:Q9H683|uniprotkb:Q5JSZ7|uniprotkb:O60270|intact:EBI-2512629|intact:EBI-947989|uniprotkb:Q68CR0|intact:EBI-2559356|uniprotkb:Q96EI9|ensembl:ENSP00000508005|ensembl:ENSP00000508048 intact:EBI-3957603|uniprotkb:P15463 psi-mi:prc2b_human(display_long)|uniprotkb:PRRC2B(gene name)|psi-mi:PRRC2B(display_short)|uniprotkb:HLA-B-associated transcript 2-like 1(gene name synonym)|uniprotkb:KIAA0515(gene name synonym)|uniprotkb:BAT2L(gene name synonym)|uniprotkb:BAT2L1(gene name synonym)|uniprotkb:Proline-rich coiled-coil protein 2B(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957609|imex:IM-15418-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037450.2|ensembl:ENST00000682501|ensembl:ENSP00000508073|ensembl:ENSP00000508048|ensembl:ENSP00000508005|ensembl:ENSG00000288701(gene)|ensembl:ENST00000683519(transcript)|ensembl:ENST00000684596(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:Q5JSZ5 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:N1MgJl3k+WJTF+XUf5VFIB06B909606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:AE97DCED583A9C7B|rigid:+H83/W9rM/ryTyGwtQDdQtO/9cU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q5TD97 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957640|imex:IM-15418-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606 intact-crc:78A41A9B0AAB5AE0|rigid:19VluwKsHUOkVToriC65dzZh9hM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9BYR6 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3957694|ensembl:ENSP00000375428|ensembl:ENSP00000458618|uniprotkb:Q52LP0|uniprotkb:Q6NTD4 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:kra33_human(display_long)|uniprotkb:KRTAP3-3(gene name)|psi-mi:KRTAP3-3(display_short)|uniprotkb:KAP3.3(gene name synonym)|uniprotkb:KRTAP3.3(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 3.3(gene name synonym)|uniprotkb:Keratin-associated protein 3.3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957697|imex:IM-15418-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000212899(gene)|ensembl:ENSG00000263101(gene)|ensembl:ENST00000391586(transcript)|ensembl:ENST00000572132(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR007659(Keratin, high-sulphur matrix protein)|reactome:R-HSA-6805567|refseq:NP_149441.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:a8BWIYBV0PSxkm2/GeOWG3wKQwQ9606 intact-crc:9699E483B67F30CA|rigid:jg/WFFyMMXjF+20Tl2sKLX4Bcyo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:O95967 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957629|imex:IM-15418-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606 intact-crc:7452FB3740BB0101|rigid:MAJY0VpcewRqeAVqhpbIsil2suI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:O15294 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957744|imex:IM-15418-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 intact-crc:A9C426007B2B16DD|rigid:dzvvtyqbeRiuPlX45MnfkofUxMg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9NR12 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-350517|uniprotkb:Q14250|uniprotkb:Q5XG82|uniprotkb:Q6NVZ5|uniprotkb:Q96C91|uniprotkb:Q9BXB8|uniprotkb:Q9BXB9|intact:EBI-2556830|ensembl:ENSP00000348099 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pdli7_human(display_long)|uniprotkb:LIM mineralization protein(gene name synonym)|uniprotkb:Protein enigma(gene name synonym)|uniprotkb:PDLIM7(gene name)|psi-mi:PDLIM7(display_short)|uniprotkb:ENIGMA(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957756|imex:IM-15418-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_976227.1|refseq:NP_998801.1|refseq:NP_005442.2|ensembl:ENST00000355572|ensembl:ENSP00000347776|ensembl:ENSP00000348099|ensembl:ENST00000359895|ensembl:ENSP00000352964|ensembl:ENST00000393551|ensembl:ENSP00000377182|ensembl:ENST00000486828|ensembl:ENSP00000439157|ensembl:ENST00000493815|ensembl:ENSP00000431236|ensembl:ENSG00000196923(gene)|ensembl:ENST00000355841(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031941"(filamentous actin)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036034|rcsb pdb:2Q3G|reactome:R-HSA-8853659 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:XBVF0Y1DFqIYbnt/e/rYqS/m4d09606 intact-crc:44ED012BEFCC4DCF|rigid:rIzwGyqxbX4jKGWe5JqgVRGr7y8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q92824 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-751290|uniprotkb:Q13527|intact:EBI-947942|uniprotkb:Q96EP4|uniprotkb:F5H2G7|ensembl:ENSP00000446280 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pcsk5_human(display_long)|uniprotkb:Subtilisin/kexin-like protease PC5(gene name synonym)|uniprotkb:PCSK5(gene name)|psi-mi:PCSK5(display_short)|uniprotkb:PC5(gene name synonym)|uniprotkb:PC6(gene name synonym)|uniprotkb:Proprotein convertase 5(gene name synonym)|uniprotkb:Proprotein convertase 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957751|imex:IM-15418-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001177411.1|refseq:NP_006191.2|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0019058"(viral life cycle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030323"(respiratory tube development)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042277"(peptide binding)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0051004"(regulation of lipoprotein lipase activity)|go:"GO:0140447"(cytokine precursor processing)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR006212(Furin-like repeat)|ensembl:ENSG00000099139(gene)|ensembl:ENST00000545128(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002001"(renin secretion into blood stream)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006465"(signal peptide processing)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008233"(peptidase activity)|go:"GO:0009952"(anterior/posterior pattern specification)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032778|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|reactome:R-HSA-167060|reactome:R-HSA-8963889 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:5e1gFIyzA+oooSthhUnV8rid4Ms9606 intact-crc:AD278B426738CA40|rigid:lXefh81/fA6vxbXS1gKhZfne8ZM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:P22736 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-721550|uniprotkb:B4DML7|ensembl:ENSP00000243050|ensembl:ENSP00000378301|ensembl:ENSP00000378302|uniprotkb:Q15627|uniprotkb:Q53Y00|uniprotkb:Q6IBU8 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:nr4a1_human(display_long)|uniprotkb:Orphan nuclear receptor HMR(gene name synonym)|uniprotkb:Early response protein NAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR3(gene name synonym)|uniprotkb:ST-59(gene name synonym)|uniprotkb:GFRP1(gene name synonym)|uniprotkb:HMR(gene name synonym)|uniprotkb:NAK1(gene name synonym)|uniprotkb:NR4A1(gene name)|psi-mi:NR4A1(display_short)|uniprotkb:Nuclear hormone receptor NUR/77(gene name synonym)|uniprotkb:Testicular receptor 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957738|imex:IM-15418-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001189162.1|refseq:NP_002126.2|refseq:NP_775180.1|ensembl:ENSG00000123358(gene)|ensembl:ENST00000243050(transcript)|ensembl:ENST00000394824(transcript)|ensembl:ENST00000394825(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|dip:DIP-40392N|refseq:XP_005268881.1|refseq:XP_006719426.1|refseq:XP_006719427.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014860"(neurotransmitter secretion involved in regulation of skeletal muscle contraction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0098793"(presynapse)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003071(Orphan nuclear receptor, HMR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P22736|rcsb pdb:2QW4|rcsb pdb:3V3E|rcsb pdb:3V3Q|rcsb pdb:4JGV|rcsb pdb:4KZI|rcsb pdb:4KZJ|rcsb pdb:4KZM|rcsb pdb:4RE8|rcsb pdb:4REE|rcsb pdb:4REF|rcsb pdb:4RZE|rcsb pdb:4RZF|rcsb pdb:4RZG|rcsb pdb:4WHF|rcsb pdb:4WHG|rcsb pdb:6KZ5|rcsb pdb:6LC1|reactome:R-HSA-198693|reactome:R-HSA-383280|reactome:R-HSA-5674400 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:yocf+C94vprIeNXXB89p3tqzW/c9606 intact-crc:17792C5840EB266C|rigid:bDHhENTTvXrKHPLwT3fAy+jreGI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q3V5L5 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3957727|uniprotkb:Q6P3S8|uniprotkb:Q6P6B3|uniprotkb:Q766X5|uniprotkb:Q76D04|uniprotkb:Q96LS2|ensembl:ENSP00000456037 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:mgt5b_human(display_long)|uniprotkb:MGAT5B(gene name)|psi-mi:MGAT5B(display_short)|uniprotkb:KIAA2008(gene name synonym)|uniprotkb:Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B(gene name synonym)|uniprotkb:GlcNAc-T Vb(gene name synonym)|uniprotkb:Mannoside acetylglucosaminyltransferase 5B(gene name synonym)|uniprotkb:N-acetylglucosaminyl-transferase Vb(gene name synonym)|uniprotkb:N-acetylglucosaminyltransferase IX(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957725|imex:IM-15418-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001186101.1|refseq:NP_653278.2|refseq:NP_945193.1|ensembl:ENSG00000167889(gene)|ensembl:ENST00000569840(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018242"(protein O-linked glycosylation via serine)|go:"GO:0030144"(alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0030145"(manganese ion binding)|interpro:IPR026116 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:YQ7JoeC1hwjfy03NcnLBLmdZhxc9606 intact-crc:0914BCDB294FB240|rigid:CVWhx0g1rwyzvX5fY7DlXsWQpbg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92802 uniprotkb:P09022 intact:EBI-2514973|uniprotkb:A3KME8|ensembl:ENSP00000267068|ensembl:ENSP00000501416|ensembl:ENSP00000501516|ensembl:ENSP00000501518|ensembl:ENSP00000501537 intact:EBI-3957603|uniprotkb:P15463 psi-mi:n42l2_human(display_long)|uniprotkb:N4BP2L2(gene name)|psi-mi:N4BP2L2(display_short)|uniprotkb:CG005(gene name synonym)|uniprotkb:PFAAP5(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 5(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957733|imex:IM-15418-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016875836.1|refseq:XP_016875837.1|refseq:XP_016875838.1|refseq:NP_055702.1|ensembl:ENSG00000244754(gene)|ensembl:ENST00000267068(transcript)|ensembl:ENST00000674349(transcript)|ensembl:ENST00000674421(transcript)|ensembl:ENST00000674465(transcript)|ensembl:ENST00000674484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001824"(blastocyst development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|interpro:IPR026302|interpro:IPR026568|interpro:IPR027417|mint:Q92802 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:a7wRNCzoB/ImcDT7U8E5355qX1A9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:36D2FC6B21F821CF|rigid:C3qs3hvRC9NhKAXx0BgYB2VwXmE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:O60711 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957720|imex:IM-15418-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001137467.1|refseq:NP_001294880.1|refseq:NP_004802.1|ensembl:ENSG00000110031(gene)|ensembl:ENST00000395074(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042995"(cell projection)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050859"(negative regulation of B cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606 intact-crc:77C0CDA9EC21F28E|rigid:PZp9VeX4JXOQHLdoeUjYd7h9R04 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UHV8 uniprotkb:P09022 intact:EBI-3957707|ensembl:ENSP00000221797|uniprotkb:C5HZ15 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pp13_human(display_long)|uniprotkb:LGALS13(gene name)|psi-mi:LGALS13(display_short)|uniprotkb:PLAC8(gene name synonym)|uniprotkb:Galectin-13(gene name synonym)|uniprotkb:Placental tissue protein 13(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957710|imex:IM-15418-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105198(gene)|ensembl:ENST00000221797(transcript)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030653|interpro:IPR044156|rcsb pdb:1F87|rcsb pdb:5XG7|rcsb pdb:5XG8|rcsb pdb:5Y03|rcsb pdb:6A62|rcsb pdb:6A63|rcsb pdb:6A64|rcsb pdb:6A65|rcsb pdb:6A66|rcsb pdb:6KJW|rcsb pdb:6KJX|rcsb pdb:6KJY|refseq:NP_037400.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:V4UZbFLEBFoDqXzyLe4a0O+PO3g9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:8D8236466DD7A87D|rigid:/ug9MNxOYCTG7fXkVqdP+Ukh+Rc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q8N448 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957715|imex:IM-15418-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:29FA270181B24F99|rigid:WPlOS7yj6az6g2bDYymm9av5md4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9BQ66 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-739863|uniprotkb:A3KMC5|uniprotkb:Q495I0|ensembl:ENSP00000377582|ensembl:ENSP00000458979 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:kr412_human(display_long)|uniprotkb:KRTAP4-12(gene name)|psi-mi:KRTAP4-12(display_short)|uniprotkb:KAP4.12(gene name synonym)|uniprotkb:KRTAP4.12(gene name synonym)|uniprotkb:Keratin-associated protein 4.12(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.12(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957701|imex:IM-15418-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_114060.1|ensembl:ENSG00000213416(gene)|ensembl:ENSG00000263236(gene)|ensembl:ENST00000394014(transcript)|ensembl:ENST00000571271(transcript)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:XLiYOwNd549kn287BJWgx5zmDCY9606 intact-crc:E40264BD25D730DA|rigid:Pp8J7VVSdTbDv3iuHVR1MspOhUc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BYR7 uniprotkb:P09022 intact:EBI-751260|ensembl:ENSP00000375429|ensembl:ENSP00000459215 intact:EBI-3957603|uniprotkb:P15463 psi-mi:kra32_human(display_long)|uniprotkb:Keratin-associated protein 3.2(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 3.2(gene name synonym)|uniprotkb:KRTAP3-2(gene name)|psi-mi:KRTAP3-2(display_short)|uniprotkb:KAP3.2(gene name synonym)|uniprotkb:KRTAP3.2(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957680|imex:IM-15418-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_114165.1|ensembl:ENSG00000212900(gene)|ensembl:ENSG00000263296(gene)|ensembl:ENST00000391587(transcript)|ensembl:ENST00000575409(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR007659(Keratin, high-sulphur matrix protein)|reactome:R-HSA-6805567 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:2AFUGT7g1vlyF9kv3x5NYu/bv9c9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:9699E476B67F308F|rigid:7bWj7H0z/0AHInJVwHS+cc+P93M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q6PEX3 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3957672|ensembl:ENSP00000353742|uniprotkb:B0RZD3 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:kr261_human(display_long)|uniprotkb:KRTAP26-1(gene name)|psi-mi:KRTAP26-1(display_short)|uniprotkb:KAP26.1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957675|imex:IM-15418-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000197683(gene)|ensembl:ENST00000360542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|refseq:NP_981950.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:VKgQPRg2qO2FXQx0fQ/dd/5kMws9606 intact-crc:7FBEC40F2F5D8EFA|rigid:+tRqTru/+wWQvtNEztE7QbHEDaY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P31249 uniprotkb:P09022 intact:EBI-3957655|ensembl:ENSP00000249440|ensembl:ENSP00000386498|ensembl:ENSP00000507129|uniprotkb:Q99955|uniprotkb:Q9BSC5 intact:EBI-3957603|uniprotkb:P15463 psi-mi:hxd3_human(display_long)|uniprotkb:HOXD3(gene name)|psi-mi:HOXD3(display_short)|uniprotkb:HOX1D(gene name synonym)|uniprotkb:HOX4A(gene name synonym)|uniprotkb:Homeobox protein Hox-4A(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957658|imex:IM-15418-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128652(gene)|ensembl:ENST00000249440(transcript)|ensembl:ENST00000410016(transcript)|ensembl:ENST00000683222(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011509367.1|refseq:XP_011509368.1|refseq:NP_008829.3|refseq:XP_005246566.1|refseq:XP_005246567.1|refseq:XP_005246568.1|refseq:XP_005246570.1|refseq:XP_006712540.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:6egSlcCWXDnEWbOnwNGI/0ZxBM49606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:B6EF24C2F8CB3A6B|rigid:FJfa1SPJXQxuwxi6e5KExlh5W7U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:P49639 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-740785|uniprotkb:O43363|uniprotkb:B2R8U7|uniprotkb:A4D184 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:hxa1_human(display_long)|uniprotkb:Homeobox protein Hox-1F(gene name synonym)|uniprotkb:HOXA1(gene name)|psi-mi:HOXA1(display_short)|uniprotkb:HOX1F(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957650|imex:IM-15418-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_005513.1|refseq:NP_705873.2|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|reactome:R-HSA-5617472|mint:P49639 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:QjQVU0uonSpj5vQU0pgzXuXmW3Y9606 intact-crc:1711BE50601890A1|rigid:DI8lXIALke+tL4XULOfKvdXbXuc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q96LI6 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957663|imex:IM-15418-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606 intact-crc:60E5924A5D3FF4CC|rigid:Gs5Nndu/YZHEFTQN4H29zUsRovQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15162 uniprotkb:P09022 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957769|imex:IM-15418-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:3C1A59C73B53219F|rigid:dQLrrmwZjqps8IQmsWKrnhcZkyA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRQ2 uniprotkb:P09022 intact:EBI-769257|uniprotkb:Q2TTR3|uniprotkb:Q658L3|uniprotkb:Q7Z505|uniprotkb:A8K2E9|uniprotkb:Q6ZR73|ensembl:ENSP00000347038|ensembl:ENSP00000399315|ensembl:ENSP00000419040 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pls4_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 4"(gene name synonym)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 43 protein(gene name synonym)|uniprotkb:PLSCR4(gene name)|psi-mi:PLSCR4(display_short)|uniprotkb:GIG43(orf name) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957773|imex:IM-15418-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005247711.1|refseq:XP_005247712.1|refseq:NP_001121778.1|refseq:NP_001170775.1|refseq:NP_065086.2|refseq:NP_001121776.1|refseq:NP_001121777.1|refseq:XP_011511333.1|ensembl:ENSP00000347038|ensembl:ENST00000433593|ensembl:ENSP00000415605|ensembl:ENSP00000399315|ensembl:ENSP00000419040|ensembl:ENSG00000114698(gene)|ensembl:ENST00000354952(transcript)|ensembl:ENST00000446574(transcript)|ensembl:ENST00000493382(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR005552(Scramblase)|rcsb pdb:3Q5U go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:bqEhBoGZZebMZn4JWpg/X0qU49A9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:28ED0116AFCC4DDE|rigid:YFq+B+CkMVK7CIIWWxAzw2sQLK0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9GZV8 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957811|imex:IM-15418-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 intact-crc:8BE5B7A66363127D|rigid:Rpzld7W5kF8OR3Tyo1PaN5Cltbw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9BYM8 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957829|imex:IM-15418-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606 intact-crc:7A49E11F857F337B|rigid:zMfgpRgt74lZ2ez3i2DrL/OSDu8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062 uniprotkb:P09022 intact:EBI-740322|uniprotkb:Q92516|uniprotkb:Q92517|uniprotkb:Q92518|uniprotkb:Q96J26|uniprotkb:D3DSU9|ensembl:ENSP00000318102|ensembl:ENSP00000380486 intact:EBI-3957603|uniprotkb:P15463 psi-mi:rbpms_human(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957851|imex:IM-15418-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008710.1|refseq:NP_001008711.1|refseq:NP_001008712.1|refseq:NP_006858.1|ensembl:ENSG00000157110(gene)|ensembl:ENST00000320203(transcript)|ensembl:ENST00000397323(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q93062|rcsb pdb:1BNY|rcsb pdb:5CYJ|rcsb pdb:5DET|refseq:XP_016868475.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:3PsLJDzqs+19eVFeQlN+yLielYM9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:FEA917191850D4CE|rigid:0yldLlCXvM+RYIG6O/Tv5XAaOwo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9UGC6 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3918154|uniprotkb:Q9UJS8|uniprotkb:Q5TF49|uniprotkb:Q8TD61|ensembl:ENSP00000206262|ensembl:ENSP00000356194 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:rgs17_human(display_long)|uniprotkb:RGS17(gene name)|psi-mi:RGS17(display_short)|uniprotkb:RGSZ2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957867|imex:IM-15418-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_036551.3|ensembl:ENSG00000091844(gene)|ensembl:ENST00000206262(transcript)|ensembl:ENST00000367225(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036305|rcsb pdb:1ZV4|rcsb pdb:6AM3|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-418597|dip:DIP-59095N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:RPGO5Be/i36A1eH1BQSw/4Kqk6Q9606 intact-crc:8E79E3DC19B4ABCE|rigid:IuILEvdn8Syg3ov3/YrxLMuzerE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:O76081 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-1052678|uniprotkb:Q96BG9|ensembl:ENSP00000297313 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:rgs20_human(display_long)|uniprotkb:Regulator of Gz-selective protein signaling 1(gene name synonym)|uniprotkb:Gz-selective GTPase-activating protein(gene name synonym)|uniprotkb:RGS20(gene name)|psi-mi:RGS20(display_short)|uniprotkb:RGSZ1(gene name synonym)|uniprotkb:ZGAP1(gene name synonym)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957895|imex:IM-15418-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_003693.2|refseq:NP_733466.1|refseq:NP_001273602.1|refseq:NP_001273603.1|refseq:NP_001273604.1|ensembl:ENSG00000147509(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036305|mint:O76081|reactome:R-HSA-418594|reactome:R-HSA-418597|ensembl:ENST00000297313(transcript)|refseq:XP_011515924.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:ZGGorrcKaXGhS8ds2O+UE5TY13Y9606 intact-crc:B982063F7AF6B8EF|rigid:CtKeXQ9B6wUi0/zDPZB9OgEmHuE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43609 uniprotkb:P09022 intact:EBI-3866665|uniprotkb:Q6PNE0|uniprotkb:D3DNX6|ensembl:ENSP00000343785|ensembl:ENSP00000377871|ensembl:ENSP00000480540|ensembl:ENSP00000481675|ensembl:ENSP00000498292 intact:EBI-3957603|uniprotkb:P15463 psi-mi:spy1_human(display_long)|uniprotkb:SPRY1(gene name)|psi-mi:SPRY1(display_short) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957899|imex:IM-15418-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005832.1|refseq:NP_955359.1|refseq:NP_001244967.1|refseq:NP_001244968.1|refseq:XP_005262743.1|ensembl:ENSG00000164056(gene)|ensembl:ENST00000339241(transcript)|ensembl:ENST00000394339(transcript)|ensembl:ENST00000610581(transcript)|ensembl:ENST00000622283(transcript)|ensembl:ENST00000651917(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001759"(organ induction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR007875(Sprouty)|interpro:IPR030783|mint:O43609|reactome:R-HSA-182971|refseq:XP_016863124.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:tbucIEQYibDQbBC1xVIZVDH2nIY9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:307B7C5E6B928395|rigid:17hz9c6JSYPpHbODvpoexfAcMAE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43597 uniprotkb:P09022 intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9 intact:EBI-3957603|uniprotkb:P15463 psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957909|imex:IM-15418-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:u1omauzisc6MdZlogMotUmtauSI9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:0E1B6FBF2CEA852E|rigid:fqXDYGCLPusXKfnKu3imWO9A2yg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13077 uniprotkb:P09022 intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183 intact:EBI-3957603|uniprotkb:P15463 psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957913|imex:IM-15418-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:95D917636D50D237|rigid:sYRqrzAd2DAJAePs/4hW68X8kUg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y2Y4 uniprotkb:P09022 intact:EBI-954098|ensembl:ENSP00000376035|ensembl:ENSP00000262630|uniprotkb:Q8WVP2 intact:EBI-3957603|uniprotkb:P15463 psi-mi:zbt32_human(display_long)|uniprotkb:Fanconi anemia zinc finger protein(gene name synonym)|uniprotkb:Testis zinc finger protein(gene name synonym)|uniprotkb:FANCC-interacting protein(gene name synonym)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)|uniprotkb:FAZF(gene name synonym)|uniprotkb:TZFP(gene name synonym)|uniprotkb:ZNF538(gene name synonym)|uniprotkb:Zinc finger protein 538(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957968|imex:IM-15418-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000262630(transcript)|ensembl:ENST00000392197(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:3M5B|ensembl:ENSG00000011590(gene)|refseq:NP_055198.1|refseq:NP_001303831.1|refseq:NP_001303832.1|refseq:XP_011525020.1|refseq:XP_016882078.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:gAas4U/RF96mVnqIK9dlhZ55zEY9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:09B6A47F3A81D742|rigid:Tt1gQtQdFKmzZI8wdl9FVfxQCG0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36406 uniprotkb:P09022 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-3957603|uniprotkb:P15463 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957934|imex:IM-15418-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:AA5511F22EF7F299|rigid:kBbPcxpCpCVsJOeBJwj++Pj/SUs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q05516 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957946|imex:IM-15418-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606 intact-crc:5F3EDCDF2073EC86|rigid:VHydg89Xjz1vQWvxhClE7OVMx+M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15654 uniprotkb:P09022 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-3957603|uniprotkb:P15463 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957939|imex:IM-15418-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:42434D5D856CECF8|rigid:1rY6hGt3dCeM1tjWrvEWY5WudgE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12933 uniprotkb:P09022 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 intact:EBI-3957603|uniprotkb:P15463 psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3957930|imex:IM-15418-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:8B298FC4BE0D2622|rigid:nWSG5dOw+fIqrzwbTd5yjJhVlGI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96D53 uniprotkb:P09022 intact:EBI-3957978|uniprotkb:Q8TAJ1|uniprotkb:Q9HA52|ensembl:ENSP00000315118|ensembl:ENSP00000470876|ensembl:ENSP00000470916|ensembl:ENSP00000503480|ensembl:ENSP00000503944|ensembl:ENSP00000504072|ensembl:ENSP00000504085|ensembl:ENSP00000504845 intact:EBI-3957603|uniprotkb:P15463 psi-mi:coq8b_human(display_long)|uniprotkb:COQ8B(gene name)|psi-mi:COQ8B(display_short)|uniprotkb:ADCK4(gene name synonym)|uniprotkb:AarF domain-containing protein kinase 4(gene name synonym)|uniprotkb:Coenzyme Q protein 8B(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958001|imex:IM-15418-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001136027.1|refseq:NP_079152.3|ensembl:ENSG00000123815(gene)|ensembl:ENST00000324464(transcript)|ensembl:ENST00000594720(transcript)|ensembl:ENST00000601967(transcript)|ensembl:ENST00000677018(transcript)|ensembl:ENST00000678404(transcript)|ensembl:ENST00000678419(transcript)|ensembl:ENST00000678467(transcript)|ensembl:ENST00000679130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034638|interpro:IPR034646|mint:Q96D53 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:UAfHqMHShcF12Ijycxi7OWs0KFE9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:A01516EC9F925EBB|rigid:pnJMN+9wuqLuk8Es4UNWGPrgA3U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P28799 uniprotkb:P09022 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 intact:EBI-3957603|uniprotkb:P15463 psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958053|imex:IM-15418-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:8620ACA687CC54B3|rigid:Rhhwe8I1eAsDOISAsK6T1Kj1utE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99943 uniprotkb:P09022 intact:EBI-3893468|uniprotkb:A2BFI5|uniprotkb:Q5BL03|ensembl:ENSP00000337463|ensembl:ENSP00000364245|ensembl:ENSP00000364248|ensembl:ENSP00000372782|ensembl:ENSP00000378874|ensembl:ENSP00000378875|ensembl:ENSP00000378877|ensembl:ENSP00000382721|ensembl:ENSP00000382723|ensembl:ENSP00000382725|ensembl:ENSP00000382726|ensembl:ENSP00000382728|ensembl:ENSP00000387810|ensembl:ENSP00000388090|ensembl:ENSP00000388253|ensembl:ENSP00000388815|ensembl:ENSP00000388870|ensembl:ENSP00000389516|ensembl:ENSP00000390988|ensembl:ENSP00000392083|ensembl:ENSP00000392820|ensembl:ENSP00000394919|ensembl:ENSP00000395613|ensembl:ENSP00000395863|ensembl:ENSP00000397765|ensembl:ENSP00000398016|ensembl:ENSP00000401287|ensembl:ENSP00000401410|ensembl:ENSP00000404106|ensembl:ENSP00000405565|ensembl:ENSP00000405864|ensembl:ENSP00000406582|ensembl:ENSP00000406614|ensembl:ENSP00000406615|ensembl:ENSP00000387738|ensembl:ENSP00000408032|ensembl:ENSP00000408842|ensembl:ENSP00000410831|ensembl:ENSP00000412304|ensembl:ENSP00000412805|ensembl:ENSP00000415015|ensembl:ENSP00000407189 intact:EBI-3957603|uniprotkb:P15463 psi-mi:plca_human(display_long)|uniprotkb:AGPAT1(gene name)|psi-mi:AGPAT1(display_short)|uniprotkb:G15(gene name synonym)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 1(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase alpha(gene name synonym)|uniprotkb:Protein G15(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958005|imex:IM-15418-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512536.1|refseq:NP_006402.1|refseq:NP_116130.2|refseq:XP_005248863.1|ensembl:ENSG00000204310(gene)|ensembl:ENSG00000206324(gene)|ensembl:ENSG00000226467(gene)|ensembl:ENSG00000227642(gene)|ensembl:ENSG00000228892(gene)|ensembl:ENSG00000235758(gene)|ensembl:ENSG00000236873(gene)|ensembl:ENST00000336984(transcript)|ensembl:ENST00000375104(transcript)|ensembl:ENST00000375107(transcript)|ensembl:ENST00000383294(transcript)|ensembl:ENST00000395496(transcript)|ensembl:ENST00000395497(transcript)|ensembl:ENST00000395499(transcript)|ensembl:ENST00000399825(transcript)|ensembl:ENST00000399827(transcript)|ensembl:ENST00000399829(transcript)|ensembl:ENST00000399830(transcript)|ensembl:ENST00000399833(transcript)|ensembl:ENST00000414520(transcript)|ensembl:ENST00000414933(transcript)|ensembl:ENST00000416363(transcript)|ensembl:ENST00000417388(transcript)|ensembl:ENST00000424030(transcript)|ensembl:ENST00000425204(transcript)|ensembl:ENST00000425572(transcript)|ensembl:ENST00000427763(transcript)|ensembl:ENST00000430226(transcript)|ensembl:ENST00000430777(transcript)|ensembl:ENST00000433376(transcript)|ensembl:ENST00000433896(transcript)|ensembl:ENST00000434614(transcript)|ensembl:ENST00000436149(transcript)|ensembl:ENST00000439774(transcript)|ensembl:ENST00000440840(transcript)|ensembl:ENST00000444369(transcript)|ensembl:ENST00000446323(transcript)|ensembl:ENST00000446463(transcript)|ensembl:ENST00000448196(transcript)|ensembl:ENST00000449776(transcript)|ensembl:ENST00000451833(transcript)|ensembl:ENST00000452393(transcript)|ensembl:ENST00000452427(transcript)|ensembl:ENST00000454929(transcript)|ensembl:ENST00000455898(transcript)|ensembl:ENST00000456421(transcript)|ensembl:ENST00000456679(transcript)|ensembl:ENST00000457923(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-HSA-1483166|reactome:R-HSA-163765|ensembl:ENST00000415173(transcript) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:79aLEXZSVTqCLBYxPUnUPT5n0ME9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:F6D67CDC03CD8F6E|rigid:xpdjwUYmvuzPAUlmrdHs3AM4vIg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q96G97 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-741806|uniprotkb:Q96SV1|uniprotkb:Q9BSQ0|uniprotkb:Q567S1|ensembl:ENSP00000384080|ensembl:ENSP00000385561|ensembl:ENSP00000413209|uniprotkb:G3XAE4 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:bscl2_human(display_long)|uniprotkb:Bernardinelli-Seip congenital lipodystrophy type 2 protein(gene name synonym)|uniprotkb:BSCL2(gene name)|psi-mi:BSCL2(display_short) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958017|imex:IM-15418-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001116427.1|refseq:NP_001124174.2|refseq:NP_116056.3|ensembl:ENST00000403550(transcript)|ensembl:ENST00000407022(transcript)|ensembl:ENST00000421906(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019915"(lipid storage)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR009617(Protein of unknown function DUF1226)|rcsb pdb:6DS5|ensembl:ENSG00000168000(gene) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:YQ38hgFvVRBPt9IB4CC3ShnioxI9606 intact-crc:50BFFADE45E33114|rigid:8lNzB2rGWlW1rNIOqmgXNv+xeD8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9UK85 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-1753048|ensembl:ENSP00000221498 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:dkkl1_human(display_long)|uniprotkb:DKKL1(gene name)|psi-mi:DKKL1(display_short)|uniprotkb:SGY1(gene name synonym)|uniprotkb:Protein soggy-1(gene name synonym)|uniprotkb:Cancer/testis antigen 34(gene name synonym)|uniprotkb:UNQ735/PRO1429(orf name) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958023|imex:IM-15418-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001184230.1|refseq:NP_001184231.1|refseq:NP_055234.1|ensembl:ENSG00000104901(gene)|ensembl:ENST00000221498(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005615"(extracellular space)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000225"(negative regulation of testosterone biosynthetic process)|interpro:IPR039863 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:ssGULyz/lhHYgog/nlP3D6VGRg89606 intact-crc:70BDCEEF6DED61D9|rigid:ozSE8kMqn9RVKJ4AFwfvr5KWF6o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WUM4 uniprotkb:P09022 intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958120|imex:IM-15418-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:8EEB5C5ED245B7B5|rigid:SlWyiNr6IgXrL0SAA+W3ojdASy8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:P08237 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-514788|uniprotkb:Q16814|uniprotkb:Q16815|uniprotkb:J3KNX3|uniprotkb:Q6ZTT1|ensembl:ENSP00000309438|ensembl:ENSP00000352842|ensembl:ENSP00000446945|ensembl:ENSP00000448253|ensembl:ENSP00000449426|ensembl:ENSP00000450369 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pfkam_human(display_long)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme A(gene name synonym)|uniprotkb:PFKM(gene name)|psi-mi:PFKM(display_short)|uniprotkb:6-phosphofructokinase type A(gene name synonym)|uniprotkb:PFKX(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958125|imex:IM-15418-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_000280.1|refseq:NP_001160158.1|refseq:NP_001160159.1|refseq:NP_001160160.1|refseq:XP_016874957.1|refseq:XP_005269034.1|refseq:XP_005269035.1|refseq:XP_005269036.1|refseq:XP_011536790.1|ensembl:ENSG00000152556(gene)|ensembl:ENST00000312352(transcript)|ensembl:ENST00000359794(transcript)|ensembl:ENST00000547587(transcript)|ensembl:ENST00000550345(transcript)|ensembl:ENST00000550924(transcript)|ensembl:ENST00000551339(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0093001"(glycolysis from storage polysaccharide through glucose-1-phosphate)|go:"GO:0097228"(sperm principal piece)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P08237|rcsb pdb:4OMT|reactome:R-HSA-70171 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:tB7V3jdmnyITZLPqyAYjrTWo/UE9606 intact-crc:DC9ED70144766AE3|rigid:0Oq4P3UcH9V4H0c30rHBQbCi9ak false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q99750 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958110|imex:IM-15418-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:6991D52CC3DB741B|rigid:at9hvSvvP0EwtxLD5KgIEI02V9w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q92824 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-751290|uniprotkb:Q13527|intact:EBI-947942|uniprotkb:Q96EP4|uniprotkb:F5H2G7|ensembl:ENSP00000446280 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pcsk5_human(display_long)|uniprotkb:Subtilisin/kexin-like protease PC5(gene name synonym)|uniprotkb:PCSK5(gene name)|psi-mi:PCSK5(display_short)|uniprotkb:PC5(gene name synonym)|uniprotkb:PC6(gene name synonym)|uniprotkb:Proprotein convertase 5(gene name synonym)|uniprotkb:Proprotein convertase 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958115|imex:IM-15418-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001177411.1|refseq:NP_006191.2|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0019058"(viral life cycle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030323"(respiratory tube development)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042277"(peptide binding)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0051004"(regulation of lipoprotein lipase activity)|go:"GO:0140447"(cytokine precursor processing)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR006212(Furin-like repeat)|ensembl:ENSG00000099139(gene)|ensembl:ENST00000545128(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002001"(renin secretion into blood stream)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006465"(signal peptide processing)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008233"(peptidase activity)|go:"GO:0009952"(anterior/posterior pattern specification)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032778|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|reactome:R-HSA-167060|reactome:R-HSA-8963889 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:5e1gFIyzA+oooSthhUnV8rid4Ms9606 intact-crc:781AF2056E81F703|rigid:lXefh81/fA6vxbXS1gKhZfne8ZM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:P26371 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3958099|ensembl:ENSP00000431443|uniprotkb:Q14564|uniprotkb:Q3MIP8 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:kra59_human(display_long)|uniprotkb:KRTAP5-9(gene name)|psi-mi:KRTAP5-9(display_short)|uniprotkb:KAP5.9(gene name synonym)|uniprotkb:KRN1(gene name synonym)|uniprotkb:KRTAP5.9(gene name synonym)|uniprotkb:UHSK1(gene name synonym)|uniprotkb:Keratin, cuticle, ultrahigh sulfur 1(gene name synonym)|uniprotkb:Keratin, ultra high-sulfur matrix protein A(gene name synonym)|uniprotkb:Keratin-associated protein 5.9(gene name synonym)|uniprotkb:UHS keratin A(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 5.9(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958097|imex:IM-15418-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000254997(gene)|ensembl:ENST00000528743(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|mint:P26371|reactome:R-HSA-6805567|refseq:NP_005544.4 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:B6s6+/WKO8MfrhEgj4xz7BH/jqE9606 intact-crc:6BB01684C7838525|rigid:q2Fk9tSUOmpCl2nbQPkTNcd1SBM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9BQ66 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-739863|uniprotkb:A3KMC5|uniprotkb:Q495I0|ensembl:ENSP00000377582|ensembl:ENSP00000458979 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:kr412_human(display_long)|uniprotkb:KRTAP4-12(gene name)|psi-mi:KRTAP4-12(display_short)|uniprotkb:KAP4.12(gene name synonym)|uniprotkb:KRTAP4.12(gene name synonym)|uniprotkb:Keratin-associated protein 4.12(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.12(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958092|imex:IM-15418-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_114060.1|ensembl:ENSG00000213416(gene)|ensembl:ENSG00000263236(gene)|ensembl:ENST00000394014(transcript)|ensembl:ENST00000571271(transcript)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:XLiYOwNd549kn287BJWgx5zmDCY9606 intact-crc:741C23FB256DC21C|rigid:Pp8J7VVSdTbDv3iuHVR1MspOhUc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:P48059 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958105|imex:IM-15418-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606 intact-crc:903ED3D9D3966389|rigid:/JqGGP3ZdwXBQr9+opRFwGb3R8A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9BYR6 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3957694|ensembl:ENSP00000375428|ensembl:ENSP00000458618|uniprotkb:Q52LP0|uniprotkb:Q6NTD4 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:kra33_human(display_long)|uniprotkb:KRTAP3-3(gene name)|psi-mi:KRTAP3-3(display_short)|uniprotkb:KAP3.3(gene name synonym)|uniprotkb:KRTAP3.3(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 3.3(gene name synonym)|uniprotkb:Keratin-associated protein 3.3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958087|imex:IM-15418-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000212899(gene)|ensembl:ENSG00000263101(gene)|ensembl:ENST00000391586(transcript)|ensembl:ENST00000572132(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR007659(Keratin, high-sulphur matrix protein)|reactome:R-HSA-6805567|refseq:NP_149441.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:a8BWIYBV0PSxkm2/GeOWG3wKQwQ9606 intact-crc:644A356881230D94|rigid:jg/WFFyMMXjF+20Tl2sKLX4Bcyo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6PEX3 uniprotkb:P09022 intact:EBI-3957672|ensembl:ENSP00000353742|uniprotkb:B0RZD3 intact:EBI-3957603|uniprotkb:P15463 psi-mi:kr261_human(display_long)|uniprotkb:KRTAP26-1(gene name)|psi-mi:KRTAP26-1(display_short)|uniprotkb:KAP26.1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958077|imex:IM-15418-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197683(gene)|ensembl:ENST00000360542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|refseq:NP_981950.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:VKgQPRg2qO2FXQx0fQ/dd/5kMws9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:E55AEAF8AB04A5E0|rigid:+tRqTru/+wWQvtNEztE7QbHEDaY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9BYR7 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-751260|ensembl:ENSP00000375429|ensembl:ENSP00000459215 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:kra32_human(display_long)|uniprotkb:Keratin-associated protein 3.2(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 3.2(gene name synonym)|uniprotkb:KRTAP3-2(gene name)|psi-mi:KRTAP3-2(display_short)|uniprotkb:KAP3.2(gene name synonym)|uniprotkb:KRTAP3.2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958082|imex:IM-15418-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_114165.1|ensembl:ENSG00000212900(gene)|ensembl:ENSG00000263296(gene)|ensembl:ENST00000391587(transcript)|ensembl:ENST00000575409(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR007659(Keratin, high-sulphur matrix protein)|reactome:R-HSA-6805567 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:2AFUGT7g1vlyF9kv3x5NYu/bv9c9606 intact-crc:714AC068B33FBB4F|rigid:7bWj7H0z/0AHInJVwHS+cc+P93M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14533 uniprotkb:P09022 intact:EBI-739648|uniprotkb:Q14846|uniprotkb:Q16274|uniprotkb:Q8WU52|uniprotkb:Q9BR74|uniprotkb:Q17R48|ensembl:ENSP00000369349 intact:EBI-3957603|uniprotkb:P15463 psi-mi:krt81_human(display_long)|uniprotkb:Type II hair keratin Hb1(gene name synonym)|uniprotkb:ghHKb1(gene name synonym)|uniprotkb:Keratin-81(gene name synonym)|uniprotkb:Type-II keratin Kb21(gene name synonym)|uniprotkb:Hair keratin K2.9(gene name synonym)|uniprotkb:KRT81(gene name)|psi-mi:KRT81(display_short)|uniprotkb:KRTHB1(gene name synonym)|uniprotkb:MLN137(gene name synonym)|uniprotkb:Keratin, hair, basic, 1(gene name synonym)|uniprotkb:Metastatic lymph node 137 gene protein(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958072|imex:IM-15418-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002272.2|ensembl:ENST00000327741(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR003054(Type II keratin)|ensembl:ENSG00000205426(gene)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:Y/1YhLCN54gK8DZQyc4OqfNDwAs9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:B37BC16853DC2992|rigid:hQ6G9SGp5TWD9pVdKa+WAw8RUDU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9UKS7 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3893057|uniprotkb:Q53YJ5|uniprotkb:Q6PQC5|uniprotkb:Q6PQC6|uniprotkb:Q6PQC7|uniprotkb:Q6PQC8|uniprotkb:Q6PQD0|uniprotkb:Q6PQD1|uniprotkb:Q8N6S1|ensembl:ENSP00000412869 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:ikzf2_human(display_long)|uniprotkb:IKZF2(gene name)|psi-mi:IKZF2(display_short)|uniprotkb:HELIOS(gene name synonym)|uniprotkb:ZNFN1A2(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958067|imex:IM-15418-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:XP_016859078.1|refseq:XP_016859079.1|refseq:XP_011509116.1|refseq:NP_001072994.1|refseq:NP_057344.2|refseq:XP_005246441.1|refseq:XP_005246442.1|ensembl:ENSG00000030419(gene)|ensembl:ENST00000434687(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:7LPS - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:2NKseBTmX2D5I+x4feYj+RdpPIc9606 intact-crc:191B1F180495E1B4|rigid:PR/PlNuNdJl38am3yoCRRlqfPvk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q99697 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-1175211|uniprotkb:O60578|uniprotkb:O60579|uniprotkb:O60580|uniprotkb:Q9BY17|ensembl:ENSP00000347004|ensembl:ENSP00000378095|ensembl:ENSP00000481951|ensembl:ENSP00000484763|uniprotkb:B2RA02|uniprotkb:B3KXS0|uniprotkb:Q3KQX9|uniprotkb:A8K6C6 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pitx2_human(display_long)|uniprotkb:RIEG bicoid-related homeobox transcription factor(gene name synonym)|uniprotkb:Solurshin(gene name synonym)|uniprotkb:ALL1-responsive protein ARP1(gene name synonym)|uniprotkb:PITX2(gene name)|psi-mi:PITX2(display_short)|uniprotkb:ARP1(gene name synonym)|uniprotkb:RGS(gene name synonym)|uniprotkb:RIEG(gene name synonym)|uniprotkb:RIEG1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 2(gene name synonym)|uniprotkb:Homeobox protein PITX2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958130|imex:IM-15418-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000164093(gene)|ensembl:ENST00000354925(transcript)|ensembl:ENST00000394595(transcript)|ensembl:ENST00000613094(transcript)|ensembl:ENST00000614423(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_000316.2|refseq:NP_001191326.1|refseq:NP_001191327.1|refseq:NP_001191328.1|refseq:NP_700475.1|refseq:NP_700476.1|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035993"(deltoid tuberosity development)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060126"(somatotropin secreting cell differentiation)|go:"GO:0060127"(prolactin secreting cell differentiation)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061325"(cell proliferation involved in outflow tract morphogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0070986"(left/right axis specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|mint:Q99697|rcsb pdb:2L7F|rcsb pdb:2L7M|rcsb pdb:2LKX|reactome:R-HSA-8866906|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|refseq:XP_011530329.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:JWKFsTNDJOefVhq9VKgHa4A1C8g9606 intact-crc:01AF5F50A9D4D16B|rigid:1fnsUKyWcmsZXI0ypmDSG82nkTs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q9NRQ2 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-769257|uniprotkb:Q2TTR3|uniprotkb:Q658L3|uniprotkb:Q7Z505|uniprotkb:A8K2E9|uniprotkb:Q6ZR73|ensembl:ENSP00000347038|ensembl:ENSP00000399315|ensembl:ENSP00000419040 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pls4_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 4"(gene name synonym)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 43 protein(gene name synonym)|uniprotkb:PLSCR4(gene name)|psi-mi:PLSCR4(display_short)|uniprotkb:GIG43(orf name) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958135|imex:IM-15418-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:XP_005247711.1|refseq:XP_005247712.1|refseq:NP_001121778.1|refseq:NP_001170775.1|refseq:NP_065086.2|refseq:NP_001121776.1|refseq:NP_001121777.1|refseq:XP_011511333.1|ensembl:ENSP00000347038|ensembl:ENST00000433593|ensembl:ENSP00000415605|ensembl:ENSP00000399315|ensembl:ENSP00000419040|ensembl:ENSG00000114698(gene)|ensembl:ENST00000354952(transcript)|ensembl:ENST00000446574(transcript)|ensembl:ENST00000493382(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR005552(Scramblase)|rcsb pdb:3Q5U - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:bqEhBoGZZebMZn4JWpg/X0qU49A9606 intact-crc:F7C4044DFA7A34BB|rigid:YFq+B+CkMVK7CIIWWxAzw2sQLK0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14088 uniprotkb:P09022 intact:EBI-744685|uniprotkb:Q5JUZ6|uniprotkb:Q92465|ensembl:ENSP00000257017 intact:EBI-3957603|uniprotkb:P15463 psi-mi:rb33a_human(display_long)|uniprotkb:Small GTP-binding protein S10(gene name synonym)|uniprotkb:RAB33A(gene name)|psi-mi:RAB33A(display_short)|uniprotkb:RABS10(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958140|imex:IM-15418-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004785.1|interpro:IPR041822|reactome:R-HSA-8854214|reactome:R-HSA-8873719|interpro:IPR027417|ensembl:ENSG00000134594(gene)|ensembl:ENST00000257017(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0032482"(Rab protein signal transduction)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:E97stXWvkGPUamSzsiejNoY4S789606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:869B21DDB5DA7E24|rigid:pnAZJByddiNUTUZOKZZkeBdSYlY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H4F8 uniprotkb:P09022 intact:EBI-2801103|uniprotkb:B2R7P5|uniprotkb:Q96F78|uniprotkb:A8K1S3|ensembl:ENSP00000370680 intact:EBI-3957603|uniprotkb:P15463 psi-mi:smoc1_human(display_long)|uniprotkb:Secreted modular calcium-binding protein 1(gene name synonym)|uniprotkb:SMOC1(gene name)|psi-mi:SMOC1(display_short) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958144|imex:IM-15418-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001030024.1|refseq:NP_071420.1|ensembl:ENSG00000198732(gene)|ensembl:ENST00000381280(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0008201"(heparin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060173"(limb development)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|interpro:IPR036857|interpro:IPR037639 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:EA0b+kWuv4b9e19gotvuaTm3GE09606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:E3F99476712B5872|rigid:3xGlGdt5N0GKfZ+9KJKuu2uAvhI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:O75865 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-743573|uniprotkb:Q9BQ45|uniprotkb:Q9P092|uniprotkb:K7ERB1|uniprotkb:K7ERQ4|ensembl:ENSP00000468612 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:tpc6a_human(display_long)|uniprotkb:TRAPPC6A(gene name)|psi-mi:TRAPPC6A(display_short)|uniprotkb:HSPC289(orf name) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958149|imex:IM-15418-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_077013.1|refseq:NP_001257821.1|refseq:NP_001257822.1|refseq:NP_001257820.1|ensembl:ENSG00000007255(gene)|ensembl:ENST00000585934(transcript)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR037992|mint:O75865|rcsb pdb:2C0J|rcsb pdb:2J3T|reactome:R-HSA-204005|reactome:R-HSA-8876198|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:1903232"(melanosome assembly)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR024096|dip:DIP-37869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:fj7bq0NxA91fevb0Iu/0+Hx05Tk9606 intact-crc:58FC3FBCB948D223|rigid:48mP1BP/ijxEz8fLaNfpanLI4NI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IYH5 uniprotkb:P09022 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 intact:EBI-3957603|uniprotkb:P15463 psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958154|imex:IM-15418-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:6799919D96643589|rigid:DoCgQ9Ez3pkuQbvtnJxZNOBOF8g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95967 uniprotkb:P09022 intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295 intact:EBI-3957603|uniprotkb:P15463 psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958029|imex:IM-15418-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:B93D687FC97951F2|rigid:MAJY0VpcewRqeAVqhpbIsil2suI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:P14770 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-1754109|intact:EBI-2350079|uniprotkb:Q14445|uniprotkb:Q92525|uniprotkb:Q8N1D1|ensembl:ENSP00000303942 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:gpix_human(display_long)|uniprotkb:GP9(gene name)|psi-mi:GP9(display_short)|uniprotkb:Glycoprotein 9(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958045|imex:IM-15418-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:XP_011511003.1|refseq:XP_011511004.1|refseq:NP_000165.1|ensembl:ENSG00000169704(gene)|ensembl:ENST00000307395(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P14770|rcsb pdb:3REZ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|refseq:XP_005247431.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:ZtxoUr0HvC9yHFE9HXSPRc20Zaw9606 intact-crc:8D40270DEF74E4E8|rigid:GwauJB20KJLtdrE/y9POrGIGXnQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09022 uniprotkb:Q96GS6 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-2870273|uniprotkb:Q6PJU2|uniprotkb:A8K0G8|uniprotkb:Q9BWL0|uniprotkb:Q8WUH9|uniprotkb:Q9H7Q9|uniprotkb:D6W5Z9|ensembl:ENSP00000292577|ensembl:ENSP00000504042 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:ab17a_human(display_long)|uniprotkb:ABHD17A(gene name)|psi-mi:ABHD17A(display_short)|uniprotkb:C19orf27(gene name synonym)|uniprotkb:FAM108A1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958036|imex:IM-15418-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:XP_011526640.1|refseq:XP_016882830.1|refseq:NP_001123583.1|refseq:NP_112490.3|ensembl:ENSG00000129968(gene)|ensembl:ENST00000292577(transcript)|ensembl:ENST00000676686(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0010008"(endosome membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099033"(anchored component of postsynaptic recycling endosome membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1905668"(positive regulation of protein localization to endosome)|interpro:IPR022742|interpro:IPR029058|mint:Q96GS6|reactome:R-HSA-9648002|go:"GO:0016020"(membrane) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:eZ6J8YENMgDhwA9IrEscvsGst+w9606 intact-crc:9B13254D5935506C|rigid:EzEjx6c5pAJw6ZVoRW6/PSNmZvo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IYX7 uniprotkb:P09022 intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58 intact:EBI-3957603|uniprotkb:P15463 psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958220|imex:IM-15418-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:13281A85B8F9DE63|rigid:MzOQaB/yKNHRVVYNRKGj9ShgCK4 false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6P1W5 uniprotkb:P09022 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 intact:EBI-3957603|uniprotkb:P15463 psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958168|imex:IM-15418-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:7D8BF3B950C2E451|rigid:JA6v6Nq+/PiH5MIpGCqvJ36GMts false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q9BSW2 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-739773|uniprotkb:B4E1X0|uniprotkb:B9EK63|ensembl:ENSP00000409382 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:efc4b_human(display_long)|uniprotkb:CRACR2A(gene name)|psi-mi:CRACR2A(display_short)|uniprotkb:Calcium release-activated calcium channel regulator 2A(gene name synonym)|uniprotkb:Calcium release-activated channel regulator 2A(gene name synonym)|uniprotkb:EFCAB4B(gene name synonym)|uniprotkb:RAB46(gene name synonym)|uniprotkb:Ras-related protein Rab-46(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958170|imex:IM-15418-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001138430.1|refseq:NP_116069.1|ensembl:ENSG00000130038(gene)|ensembl:ENST00000440314(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001772"(immunological synapse)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031982"(vesicle)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0034776"(response to histamine)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051928"(positive regulation of calcium ion transport)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:6PSD|reactome:R-HSA-6798695|interpro:IPR027417 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2021/04/12 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:IjhHTze6Dftzv9JltvNQgdATG+89606 intact-crc:84FECA0F2E0B59BC|rigid:IEIDvypss8pGlp9+6hY5OkcNJ9I false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q6UY14 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958214|imex:IM-15418-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 intact-crc:320ED6F06AB35304|rigid:o/xg+wr5ecYpgLNUx2n2fFZxP54 false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NR12 uniprotkb:P09022 intact:EBI-350517|uniprotkb:Q14250|uniprotkb:Q5XG82|uniprotkb:Q6NVZ5|uniprotkb:Q96C91|uniprotkb:Q9BXB8|uniprotkb:Q9BXB9|intact:EBI-2556830|ensembl:ENSP00000348099 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pdli7_human(display_long)|uniprotkb:LIM mineralization protein(gene name synonym)|uniprotkb:Protein enigma(gene name synonym)|uniprotkb:PDLIM7(gene name)|psi-mi:PDLIM7(display_short)|uniprotkb:ENIGMA(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958184|imex:IM-15418-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_976227.1|refseq:NP_998801.1|refseq:NP_005442.2|ensembl:ENST00000355572|ensembl:ENSP00000347776|ensembl:ENSP00000348099|ensembl:ENST00000359895|ensembl:ENSP00000352964|ensembl:ENST00000393551|ensembl:ENSP00000377182|ensembl:ENST00000486828|ensembl:ENSP00000439157|ensembl:ENST00000493815|ensembl:ENSP00000431236|ensembl:ENSG00000196923(gene)|ensembl:ENST00000355841(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031941"(filamentous actin)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036034|rcsb pdb:2Q3G|reactome:R-HSA-8853659 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:XBVF0Y1DFqIYbnt/e/rYqS/m4d09606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:CDD385B55016F724|rigid:rIzwGyqxbX4jKGWe5JqgVRGr7y8 false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92802 uniprotkb:P09022 intact:EBI-2514973|uniprotkb:A3KME8|ensembl:ENSP00000267068|ensembl:ENSP00000501416|ensembl:ENSP00000501516|ensembl:ENSP00000501518|ensembl:ENSP00000501537 intact:EBI-3957603|uniprotkb:P15463 psi-mi:n42l2_human(display_long)|uniprotkb:N4BP2L2(gene name)|psi-mi:N4BP2L2(display_short)|uniprotkb:CG005(gene name synonym)|uniprotkb:PFAAP5(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 5(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958190|imex:IM-15418-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016875836.1|refseq:XP_016875837.1|refseq:XP_016875838.1|refseq:NP_055702.1|ensembl:ENSG00000244754(gene)|ensembl:ENST00000267068(transcript)|ensembl:ENST00000674349(transcript)|ensembl:ENST00000674421(transcript)|ensembl:ENST00000674465(transcript)|ensembl:ENST00000674484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001824"(blastocyst development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|interpro:IPR026302|interpro:IPR026568|interpro:IPR027417|mint:Q92802 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:a7wRNCzoB/ImcDT7U8E5355qX1A9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:ECE71A66604AC6A7|rigid:C3qs3hvRC9NhKAXx0BgYB2VwXmE false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q8N448 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958234|imex:IM-15418-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:839B940EF761816E|rigid:WPlOS7yj6az6g2bDYymm9av5md4 false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UHV8 uniprotkb:P09022 intact:EBI-3957707|ensembl:ENSP00000221797|uniprotkb:C5HZ15 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pp13_human(display_long)|uniprotkb:LGALS13(gene name)|psi-mi:LGALS13(display_short)|uniprotkb:PLAC8(gene name synonym)|uniprotkb:Galectin-13(gene name synonym)|uniprotkb:Placental tissue protein 13(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958206|imex:IM-15418-82 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105198(gene)|ensembl:ENST00000221797(transcript)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030653|interpro:IPR044156|rcsb pdb:1F87|rcsb pdb:5XG7|rcsb pdb:5XG8|rcsb pdb:5Y03|rcsb pdb:6A62|rcsb pdb:6A63|rcsb pdb:6A64|rcsb pdb:6A65|rcsb pdb:6A66|rcsb pdb:6KJW|rcsb pdb:6KJX|rcsb pdb:6KJY|refseq:NP_037400.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:V4UZbFLEBFoDqXzyLe4a0O+PO3g9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:6488D4780D67FECB|rigid:/ug9MNxOYCTG7fXkVqdP+Ukh+Rc false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5JSZ5 uniprotkb:P09022 intact:EBI-744891|uniprotkb:Q66VZ2|uniprotkb:Q9H683|uniprotkb:Q5JSZ7|uniprotkb:O60270|intact:EBI-2512629|intact:EBI-947989|uniprotkb:Q68CR0|intact:EBI-2559356|uniprotkb:Q96EI9|ensembl:ENSP00000508005|ensembl:ENSP00000508048 intact:EBI-3957603|uniprotkb:P15463 psi-mi:prc2b_human(display_long)|uniprotkb:PRRC2B(gene name)|psi-mi:PRRC2B(display_short)|uniprotkb:HLA-B-associated transcript 2-like 1(gene name synonym)|uniprotkb:KIAA0515(gene name synonym)|uniprotkb:BAT2L(gene name synonym)|uniprotkb:BAT2L1(gene name synonym)|uniprotkb:Proline-rich coiled-coil protein 2B(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958278|imex:IM-15418-106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037450.2|ensembl:ENST00000682501|ensembl:ENSP00000508073|ensembl:ENSP00000508048|ensembl:ENSP00000508005|ensembl:ENSG00000288701(gene)|ensembl:ENST00000683519(transcript)|ensembl:ENST00000684596(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:Q5JSZ5 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:N1MgJl3k+WJTF+XUf5VFIB06B909606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:695C6E9ED840CE6E|rigid:+H83/W9rM/ryTyGwtQDdQtO/9cU false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O60711 uniprotkb:P09022 intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512 intact:EBI-3957603|uniprotkb:P15463 psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958250|imex:IM-15418-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137467.1|refseq:NP_001294880.1|refseq:NP_004802.1|ensembl:ENSG00000110031(gene)|ensembl:ENST00000395074(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042995"(cell projection)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050859"(negative regulation of B cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:B3CC0FC9C3909BF0|rigid:PZp9VeX4JXOQHLdoeUjYd7h9R04 false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q3V5L5 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3957727|uniprotkb:Q6P3S8|uniprotkb:Q6P6B3|uniprotkb:Q766X5|uniprotkb:Q76D04|uniprotkb:Q96LS2|ensembl:ENSP00000456037 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:mgt5b_human(display_long)|uniprotkb:MGAT5B(gene name)|psi-mi:MGAT5B(display_short)|uniprotkb:KIAA2008(gene name synonym)|uniprotkb:Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B(gene name synonym)|uniprotkb:GlcNAc-T Vb(gene name synonym)|uniprotkb:Mannoside acetylglucosaminyltransferase 5B(gene name synonym)|uniprotkb:N-acetylglucosaminyl-transferase Vb(gene name synonym)|uniprotkb:N-acetylglucosaminyltransferase IX(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958248|imex:IM-15418-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001186101.1|refseq:NP_653278.2|refseq:NP_945193.1|ensembl:ENSG00000167889(gene)|ensembl:ENST00000569840(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018242"(protein O-linked glycosylation via serine)|go:"GO:0030144"(alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0030145"(manganese ion binding)|interpro:IPR026116 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:YQ7JoeC1hwjfy03NcnLBLmdZhxc9606 intact-crc:6DCF850B82A500E7|rigid:CVWhx0g1rwyzvX5fY7DlXsWQpbg false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O15294 uniprotkb:P09022 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-3957603|uniprotkb:P15463 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958208|imex:IM-15418-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:C16BA993F2587049|rigid:dzvvtyqbeRiuPlX45MnfkofUxMg false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:P31249 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3957655|ensembl:ENSP00000249440|ensembl:ENSP00000386498|ensembl:ENSP00000507129|uniprotkb:Q99955|uniprotkb:Q9BSC5 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:hxd3_human(display_long)|uniprotkb:HOXD3(gene name)|psi-mi:HOXD3(display_short)|uniprotkb:HOX1D(gene name synonym)|uniprotkb:HOX4A(gene name synonym)|uniprotkb:Homeobox protein Hox-4A(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958254|imex:IM-15418-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000128652(gene)|ensembl:ENST00000249440(transcript)|ensembl:ENST00000410016(transcript)|ensembl:ENST00000683222(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011509367.1|refseq:XP_011509368.1|refseq:NP_008829.3|refseq:XP_005246566.1|refseq:XP_005246567.1|refseq:XP_005246568.1|refseq:XP_005246570.1|refseq:XP_006712540.1 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:6egSlcCWXDnEWbOnwNGI/0ZxBM49606 intact-crc:AA6831F74949D244|rigid:FJfa1SPJXQxuwxi6e5KExlh5W7U false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q5TD97 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958256|imex:IM-15418-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606 intact-crc:0A8AA5972EADEF32|rigid:19VluwKsHUOkVToriC65dzZh9hM false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:P49639 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-740785|uniprotkb:O43363|uniprotkb:B2R8U7|uniprotkb:A4D184 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:hxa1_human(display_long)|uniprotkb:Homeobox protein Hox-1F(gene name synonym)|uniprotkb:HOXA1(gene name)|psi-mi:HOXA1(display_short)|uniprotkb:HOX1F(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958288|imex:IM-15418-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_005513.1|refseq:NP_705873.2|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|reactome:R-HSA-5617472|mint:P49639 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:QjQVU0uonSpj5vQU0pgzXuXmW3Y9606 intact-crc:8B112C6AE6049EAC|rigid:DI8lXIALke+tL4XULOfKvdXbXuc false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6PEX3 uniprotkb:P09022 intact:EBI-3957672|ensembl:ENSP00000353742|uniprotkb:B0RZD3 intact:EBI-3957603|uniprotkb:P15463 psi-mi:kr261_human(display_long)|uniprotkb:KRTAP26-1(gene name)|psi-mi:KRTAP26-1(display_short)|uniprotkb:KAP26.1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958236|imex:IM-15418-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197683(gene)|ensembl:ENST00000360542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|refseq:NP_981950.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:VKgQPRg2qO2FXQx0fQ/dd/5kMws9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:583EC75B63CBF0F4|rigid:+tRqTru/+wWQvtNEztE7QbHEDaY false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:O15162 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958204|imex:IM-15418-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 intact-crc:8B979EFE180C4C6B|rigid:dQLrrmwZjqps8IQmsWKrnhcZkyA false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NRQ2 uniprotkb:P09022 intact:EBI-769257|uniprotkb:Q2TTR3|uniprotkb:Q658L3|uniprotkb:Q7Z505|uniprotkb:A8K2E9|uniprotkb:Q6ZR73|ensembl:ENSP00000347038|ensembl:ENSP00000399315|ensembl:ENSP00000419040 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pls4_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 4"(gene name synonym)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 43 protein(gene name synonym)|uniprotkb:PLSCR4(gene name)|psi-mi:PLSCR4(display_short)|uniprotkb:GIG43(orf name) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958226|imex:IM-15418-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005247711.1|refseq:XP_005247712.1|refseq:NP_001121778.1|refseq:NP_001170775.1|refseq:NP_065086.2|refseq:NP_001121776.1|refseq:NP_001121777.1|refseq:XP_011511333.1|ensembl:ENSP00000347038|ensembl:ENST00000433593|ensembl:ENSP00000415605|ensembl:ENSP00000399315|ensembl:ENSP00000419040|ensembl:ENSG00000114698(gene)|ensembl:ENST00000354952(transcript)|ensembl:ENST00000446574(transcript)|ensembl:ENST00000493382(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR005552(Scramblase)|rcsb pdb:3Q5U go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:bqEhBoGZZebMZn4JWpg/X0qU49A9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:E651759D0AA6C378|rigid:YFq+B+CkMVK7CIIWWxAzw2sQLK0 false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9GZV8 uniprotkb:P09022 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-3957603|uniprotkb:P15463 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958196|imex:IM-15418-80 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:C806CE17BFFB5413|rigid:Rpzld7W5kF8OR3Tyo1PaN5Cltbw false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BYM8 uniprotkb:P09022 intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632 intact:EBI-3957603|uniprotkb:P15463 psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958258|imex:IM-15418-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:A51FEB049F857C4A|rigid:zMfgpRgt74lZ2ez3i2DrL/OSDu8 false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q93062 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-740322|uniprotkb:Q92516|uniprotkb:Q92517|uniprotkb:Q92518|uniprotkb:Q96J26|uniprotkb:D3DSU9|ensembl:ENSP00000318102|ensembl:ENSP00000380486 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:rbpms_human(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958232|imex:IM-15418-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001008710.1|refseq:NP_001008711.1|refseq:NP_001008712.1|refseq:NP_006858.1|ensembl:ENSG00000157110(gene)|ensembl:ENST00000320203(transcript)|ensembl:ENST00000397323(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q93062|rcsb pdb:1BNY|rcsb pdb:5CYJ|rcsb pdb:5DET|refseq:XP_016868475.1 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:3PsLJDzqs+19eVFeQlN+yLielYM9606 intact-crc:A649AD89FFB32CB6|rigid:0yldLlCXvM+RYIG6O/Tv5XAaOwo false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:O76081 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-1052678|uniprotkb:Q96BG9|ensembl:ENSP00000297313 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:rgs20_human(display_long)|uniprotkb:Regulator of Gz-selective protein signaling 1(gene name synonym)|uniprotkb:Gz-selective GTPase-activating protein(gene name synonym)|uniprotkb:RGS20(gene name)|psi-mi:RGS20(display_short)|uniprotkb:RGSZ1(gene name synonym)|uniprotkb:ZGAP1(gene name synonym)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958210|imex:IM-15418-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_003693.2|refseq:NP_733466.1|refseq:NP_001273602.1|refseq:NP_001273603.1|refseq:NP_001273604.1|ensembl:ENSG00000147509(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036305|mint:O76081|reactome:R-HSA-418594|reactome:R-HSA-418597|ensembl:ENST00000297313(transcript)|refseq:XP_011515924.1 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:ZGGorrcKaXGhS8ds2O+UE5TY13Y9606 intact-crc:7E70E63DBDF2BB92|rigid:CtKeXQ9B6wUi0/zDPZB9OgEmHuE false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O43609 uniprotkb:P09022 intact:EBI-3866665|uniprotkb:Q6PNE0|uniprotkb:D3DNX6|ensembl:ENSP00000343785|ensembl:ENSP00000377871|ensembl:ENSP00000480540|ensembl:ENSP00000481675|ensembl:ENSP00000498292 intact:EBI-3957603|uniprotkb:P15463 psi-mi:spy1_human(display_long)|uniprotkb:SPRY1(gene name)|psi-mi:SPRY1(display_short) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958178|imex:IM-15418-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005832.1|refseq:NP_955359.1|refseq:NP_001244967.1|refseq:NP_001244968.1|refseq:XP_005262743.1|ensembl:ENSG00000164056(gene)|ensembl:ENST00000339241(transcript)|ensembl:ENST00000394339(transcript)|ensembl:ENST00000610581(transcript)|ensembl:ENST00000622283(transcript)|ensembl:ENST00000651917(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001759"(organ induction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR007875(Sprouty)|interpro:IPR030783|mint:O43609|reactome:R-HSA-182971|refseq:XP_016863124.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:tbucIEQYibDQbBC1xVIZVDH2nIY9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:945178B7021E1A8A|rigid:17hz9c6JSYPpHbODvpoexfAcMAE false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13077 uniprotkb:P09022 intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183 intact:EBI-3957603|uniprotkb:P15463 psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958218|imex:IM-15418-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:4F0F1D7CB908E245|rigid:sYRqrzAd2DAJAePs/4hW68X8kUg false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P36406 uniprotkb:P09022 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-3957603|uniprotkb:P15463 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958294|imex:IM-15418-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:3DBD59DE6211E234|rigid:kBbPcxpCpCVsJOeBJwj++Pj/SUs false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q05516 uniprotkb:P09022 intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4 intact:EBI-3957603|uniprotkb:P15463 psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958186|imex:IM-15418-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:9E65786F401A77CE|rigid:VHydg89Xjz1vQWvxhClE7OVMx+M false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q15654 uniprotkb:P09022 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-3957603|uniprotkb:P15463 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958302|imex:IM-15418-114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:2EE25C46EF504C76|rigid:1rY6hGt3dCeM1tjWrvEWY5WudgE false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q9Y2Y4 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-954098|ensembl:ENSP00000376035|ensembl:ENSP00000262630|uniprotkb:Q8WVP2 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:zbt32_human(display_long)|uniprotkb:Fanconi anemia zinc finger protein(gene name synonym)|uniprotkb:Testis zinc finger protein(gene name synonym)|uniprotkb:FANCC-interacting protein(gene name synonym)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)|uniprotkb:FAZF(gene name synonym)|uniprotkb:TZFP(gene name synonym)|uniprotkb:ZNF538(gene name synonym)|uniprotkb:Zinc finger protein 538(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958270|imex:IM-15418-104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENST00000262630(transcript)|ensembl:ENST00000392197(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:3M5B|ensembl:ENSG00000011590(gene)|refseq:NP_055198.1|refseq:NP_001303831.1|refseq:NP_001303832.1|refseq:XP_011525020.1|refseq:XP_016882078.1 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:gAas4U/RF96mVnqIK9dlhZ55zEY9606 intact-crc:ECE2DB9381070FD7|rigid:Tt1gQtQdFKmzZI8wdl9FVfxQCG0 false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q12933 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958182|imex:IM-15418-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 intact-crc:5C4A1F0059CA396F|rigid:nWSG5dOw+fIqrzwbTd5yjJhVlGI false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P28799 uniprotkb:P09022 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 intact:EBI-3957603|uniprotkb:P15463 psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958262|imex:IM-15418-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:A0B48F3B5F34BC05|rigid:Rhhwe8I1eAsDOISAsK6T1Kj1utE false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q8WUM4 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958180|imex:IM-15418-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606 intact-crc:C4F7B9ABE8D744F0|rigid:SlWyiNr6IgXrL0SAA+W3ojdASy8 false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q9H4F8 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-2801103|uniprotkb:B2R7P5|uniprotkb:Q96F78|uniprotkb:A8K1S3|ensembl:ENSP00000370680 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:smoc1_human(display_long)|uniprotkb:Secreted modular calcium-binding protein 1(gene name synonym)|uniprotkb:SMOC1(gene name)|psi-mi:SMOC1(display_short) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958246|imex:IM-15418-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001030024.1|refseq:NP_071420.1|ensembl:ENSG00000198732(gene)|ensembl:ENST00000381280(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0008201"(heparin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060173"(limb development)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|interpro:IPR036857|interpro:IPR037639 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:EA0b+kWuv4b9e19gotvuaTm3GE09606 intact-crc:851A3DB16A87ACF6|rigid:3xGlGdt5N0GKfZ+9KJKuu2uAvhI false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P26371 uniprotkb:P09022 intact:EBI-3958099|ensembl:ENSP00000431443|uniprotkb:Q14564|uniprotkb:Q3MIP8 intact:EBI-3957603|uniprotkb:P15463 psi-mi:kra59_human(display_long)|uniprotkb:KRTAP5-9(gene name)|psi-mi:KRTAP5-9(display_short)|uniprotkb:KAP5.9(gene name synonym)|uniprotkb:KRN1(gene name synonym)|uniprotkb:KRTAP5.9(gene name synonym)|uniprotkb:UHSK1(gene name synonym)|uniprotkb:Keratin, cuticle, ultrahigh sulfur 1(gene name synonym)|uniprotkb:Keratin, ultra high-sulfur matrix protein A(gene name synonym)|uniprotkb:Keratin-associated protein 5.9(gene name synonym)|uniprotkb:UHS keratin A(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 5.9(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958298|imex:IM-15418-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000254997(gene)|ensembl:ENST00000528743(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|mint:P26371|reactome:R-HSA-6805567|refseq:NP_005544.4 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:B6s6+/WKO8MfrhEgj4xz7BH/jqE9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:2D29FC0DA119D4C4|rigid:q2Fk9tSUOmpCl2nbQPkTNcd1SBM false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q8IYH5 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958194|imex:IM-15418-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 intact-crc:F5DF27CD7BD47195|rigid:DoCgQ9Ez3pkuQbvtnJxZNOBOF8g false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14088 uniprotkb:P09022 intact:EBI-744685|uniprotkb:Q5JUZ6|uniprotkb:Q92465|ensembl:ENSP00000257017 intact:EBI-3957603|uniprotkb:P15463 psi-mi:rb33a_human(display_long)|uniprotkb:Small GTP-binding protein S10(gene name synonym)|uniprotkb:RAB33A(gene name)|psi-mi:RAB33A(display_short)|uniprotkb:RABS10(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958222|imex:IM-15418-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004785.1|interpro:IPR041822|reactome:R-HSA-8854214|reactome:R-HSA-8873719|interpro:IPR027417|ensembl:ENSG00000134594(gene)|ensembl:ENST00000257017(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0032482"(Rab protein signal transduction)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:E97stXWvkGPUamSzsiejNoY4S789606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:7310E21DA54D7D38|rigid:pnAZJByddiNUTUZOKZZkeBdSYlY false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95967 uniprotkb:P09022 intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295 intact:EBI-3957603|uniprotkb:P15463 psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958228|imex:IM-15418-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:9574EFFE6668541F|rigid:MAJY0VpcewRqeAVqhpbIsil2suI false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P48059 uniprotkb:P09022 intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907 intact:EBI-3957603|uniprotkb:P15463 psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958292|imex:IM-15418-110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:AA53522A76972E4E|rigid:/JqGGP3ZdwXBQr9+opRFwGb3R8A false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BYR7 uniprotkb:P09022 intact:EBI-751260|ensembl:ENSP00000375429|ensembl:ENSP00000459215 intact:EBI-3957603|uniprotkb:P15463 psi-mi:kra32_human(display_long)|uniprotkb:Keratin-associated protein 3.2(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 3.2(gene name synonym)|uniprotkb:KRTAP3-2(gene name)|psi-mi:KRTAP3-2(display_short)|uniprotkb:KAP3.2(gene name synonym)|uniprotkb:KRTAP3.2(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958264|imex:IM-15418-102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_114165.1|ensembl:ENSG00000212900(gene)|ensembl:ENSG00000263296(gene)|ensembl:ENST00000391587(transcript)|ensembl:ENST00000575409(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR007659(Keratin, high-sulphur matrix protein)|reactome:R-HSA-6805567 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:2AFUGT7g1vlyF9kv3x5NYu/bv9c9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:71D462721D357102|rigid:7bWj7H0z/0AHInJVwHS+cc+P93M false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q99697 uniprotkb:P09022 intact:EBI-1175211|uniprotkb:O60578|uniprotkb:O60579|uniprotkb:O60580|uniprotkb:Q9BY17|ensembl:ENSP00000347004|ensembl:ENSP00000378095|ensembl:ENSP00000481951|ensembl:ENSP00000484763|uniprotkb:B2RA02|uniprotkb:B3KXS0|uniprotkb:Q3KQX9|uniprotkb:A8K6C6 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pitx2_human(display_long)|uniprotkb:RIEG bicoid-related homeobox transcription factor(gene name synonym)|uniprotkb:Solurshin(gene name synonym)|uniprotkb:ALL1-responsive protein ARP1(gene name synonym)|uniprotkb:PITX2(gene name)|psi-mi:PITX2(display_short)|uniprotkb:ARP1(gene name synonym)|uniprotkb:RGS(gene name synonym)|uniprotkb:RIEG(gene name synonym)|uniprotkb:RIEG1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 2(gene name synonym)|uniprotkb:Homeobox protein PITX2(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958176|imex:IM-15418-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164093(gene)|ensembl:ENST00000354925(transcript)|ensembl:ENST00000394595(transcript)|ensembl:ENST00000613094(transcript)|ensembl:ENST00000614423(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_000316.2|refseq:NP_001191326.1|refseq:NP_001191327.1|refseq:NP_001191328.1|refseq:NP_700475.1|refseq:NP_700476.1|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035993"(deltoid tuberosity development)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060126"(somatotropin secreting cell differentiation)|go:"GO:0060127"(prolactin secreting cell differentiation)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061325"(cell proliferation involved in outflow tract morphogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0070986"(left/right axis specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|mint:Q99697|rcsb pdb:2L7F|rcsb pdb:2L7M|rcsb pdb:2LKX|reactome:R-HSA-8866906|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|refseq:XP_011530329.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:JWKFsTNDJOefVhq9VKgHa4A1C8g9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:8F318663CF3D5423|rigid:1fnsUKyWcmsZXI0ypmDSG82nkTs false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q9BQ66 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-739863|uniprotkb:A3KMC5|uniprotkb:Q495I0|ensembl:ENSP00000377582|ensembl:ENSP00000458979 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:kr412_human(display_long)|uniprotkb:KRTAP4-12(gene name)|psi-mi:KRTAP4-12(display_short)|uniprotkb:KAP4.12(gene name synonym)|uniprotkb:KRTAP4.12(gene name synonym)|uniprotkb:Keratin-associated protein 4.12(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.12(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958280|imex:IM-15418-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_114060.1|ensembl:ENSG00000213416(gene)|ensembl:ENSG00000263236(gene)|ensembl:ENST00000394014(transcript)|ensembl:ENST00000571271(transcript)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein) - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:XLiYOwNd549kn287BJWgx5zmDCY9606 intact-crc:95680DA7ADE5C16D|rigid:Pp8J7VVSdTbDv3iuHVR1MspOhUc false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:O75865 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-743573|uniprotkb:Q9BQ45|uniprotkb:Q9P092|uniprotkb:K7ERB1|uniprotkb:K7ERQ4|ensembl:ENSP00000468612 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:tpc6a_human(display_long)|uniprotkb:TRAPPC6A(gene name)|psi-mi:TRAPPC6A(display_short)|uniprotkb:HSPC289(orf name) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958272|imex:IM-15418-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_077013.1|refseq:NP_001257821.1|refseq:NP_001257822.1|refseq:NP_001257820.1|ensembl:ENSG00000007255(gene)|ensembl:ENST00000585934(transcript)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR037992|mint:O75865|rcsb pdb:2C0J|rcsb pdb:2J3T|reactome:R-HSA-204005|reactome:R-HSA-8876198|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:1903232"(melanosome assembly)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR024096|dip:DIP-37869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:fj7bq0NxA91fevb0Iu/0+Hx05Tk9606 intact-crc:5289A28B286610A2|rigid:48mP1BP/ijxEz8fLaNfpanLI4NI false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q9UKS7 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3893057|uniprotkb:Q53YJ5|uniprotkb:Q6PQC5|uniprotkb:Q6PQC6|uniprotkb:Q6PQC7|uniprotkb:Q6PQC8|uniprotkb:Q6PQD0|uniprotkb:Q6PQD1|uniprotkb:Q8N6S1|ensembl:ENSP00000412869 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:ikzf2_human(display_long)|uniprotkb:IKZF2(gene name)|psi-mi:IKZF2(display_short)|uniprotkb:HELIOS(gene name synonym)|uniprotkb:ZNFN1A2(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958296|imex:IM-15418-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:XP_016859078.1|refseq:XP_016859079.1|refseq:XP_011509116.1|refseq:NP_001072994.1|refseq:NP_057344.2|refseq:XP_005246441.1|refseq:XP_005246442.1|ensembl:ENSG00000030419(gene)|ensembl:ENST00000434687(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:7LPS - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:2NKseBTmX2D5I+x4feYj+RdpPIc9606 intact-crc:A7241BB3B842B8E7|rigid:PR/PlNuNdJl38am3yoCRRlqfPvk false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q99750 uniprotkb:P09022 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-3957603|uniprotkb:P15463 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958192|imex:IM-15418-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:603B1A0995230D7F|rigid:at9hvSvvP0EwtxLD5KgIEI02V9w false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09022 uniprotkb:Q14533 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-739648|uniprotkb:Q14846|uniprotkb:Q16274|uniprotkb:Q8WU52|uniprotkb:Q9BR74|uniprotkb:Q17R48|ensembl:ENSP00000369349 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:krt81_human(display_long)|uniprotkb:Type II hair keratin Hb1(gene name synonym)|uniprotkb:ghHKb1(gene name synonym)|uniprotkb:Keratin-81(gene name synonym)|uniprotkb:Type-II keratin Kb21(gene name synonym)|uniprotkb:Hair keratin K2.9(gene name synonym)|uniprotkb:KRT81(gene name)|psi-mi:KRT81(display_short)|uniprotkb:KRTHB1(gene name synonym)|uniprotkb:MLN137(gene name synonym)|uniprotkb:Keratin, hair, basic, 1(gene name synonym)|uniprotkb:Metastatic lymph node 137 gene protein(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958238|imex:IM-15418-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_002272.2|ensembl:ENST00000327741(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR003054(Type II keratin)|ensembl:ENSG00000205426(gene)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:Y/1YhLCN54gK8DZQyc4OqfNDwAs9606 intact-crc:3BE7F29566C70314|rigid:hQ6G9SGp5TWD9pVdKa+WAw8RUDU false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96GS6 uniprotkb:P09022 intact:EBI-2870273|uniprotkb:Q6PJU2|uniprotkb:A8K0G8|uniprotkb:Q9BWL0|uniprotkb:Q8WUH9|uniprotkb:Q9H7Q9|uniprotkb:D6W5Z9|ensembl:ENSP00000292577|ensembl:ENSP00000504042 intact:EBI-3957603|uniprotkb:P15463 psi-mi:ab17a_human(display_long)|uniprotkb:ABHD17A(gene name)|psi-mi:ABHD17A(display_short)|uniprotkb:C19orf27(gene name synonym)|uniprotkb:FAM108A1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0096"(pull down) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958268|imex:IM-15418-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011526640.1|refseq:XP_016882830.1|refseq:NP_001123583.1|refseq:NP_112490.3|ensembl:ENSG00000129968(gene)|ensembl:ENST00000292577(transcript)|ensembl:ENST00000676686(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0010008"(endosome membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099033"(anchored component of postsynaptic recycling endosome membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1905668"(positive regulation of protein localization to endosome)|interpro:IPR022742|interpro:IPR029058|mint:Q96GS6|reactome:R-HSA-9648002|go:"GO:0016020"(membrane) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/07 2014/10/16 rogid:eZ6J8YENMgDhwA9IrEscvsGst+w9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:9322B772616B7DA3|rigid:EzEjx6c5pAJw6ZVoRW6/PSNmZvo false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P31249 uniprotkb:P09022 intact:EBI-3957655|ensembl:ENSP00000249440|ensembl:ENSP00000386498|ensembl:ENSP00000507129|uniprotkb:Q99955|uniprotkb:Q9BSC5 intact:EBI-3957603|uniprotkb:P15463 psi-mi:hxd3_human(display_long)|uniprotkb:HOXD3(gene name)|psi-mi:HOXD3(display_short)|uniprotkb:HOX1D(gene name synonym)|uniprotkb:HOX4A(gene name synonym)|uniprotkb:Homeobox protein Hox-4A(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958711|imex:IM-15418-120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128652(gene)|ensembl:ENST00000249440(transcript)|ensembl:ENST00000410016(transcript)|ensembl:ENST00000683222(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011509367.1|refseq:XP_011509368.1|refseq:NP_008829.3|refseq:XP_005246566.1|refseq:XP_005246567.1|refseq:XP_005246568.1|refseq:XP_005246570.1|refseq:XP_006712540.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:6egSlcCWXDnEWbOnwNGI/0ZxBM49606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:4471B03F2B7CDEA5|rigid:FJfa1SPJXQxuwxi6e5KExlh5W7U false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q9NR12 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-350517|uniprotkb:Q14250|uniprotkb:Q5XG82|uniprotkb:Q6NVZ5|uniprotkb:Q96C91|uniprotkb:Q9BXB8|uniprotkb:Q9BXB9|intact:EBI-2556830|ensembl:ENSP00000348099 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pdli7_human(display_long)|uniprotkb:LIM mineralization protein(gene name synonym)|uniprotkb:Protein enigma(gene name synonym)|uniprotkb:PDLIM7(gene name)|psi-mi:PDLIM7(display_short)|uniprotkb:ENIGMA(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958735|imex:IM-15418-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_976227.1|refseq:NP_998801.1|refseq:NP_005442.2|ensembl:ENST00000355572|ensembl:ENSP00000347776|ensembl:ENSP00000348099|ensembl:ENST00000359895|ensembl:ENSP00000352964|ensembl:ENST00000393551|ensembl:ENSP00000377182|ensembl:ENST00000486828|ensembl:ENSP00000439157|ensembl:ENST00000493815|ensembl:ENSP00000431236|ensembl:ENSG00000196923(gene)|ensembl:ENST00000355841(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031941"(filamentous actin)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036034|rcsb pdb:2Q3G|reactome:R-HSA-8853659 go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:XBVF0Y1DFqIYbnt/e/rYqS/m4d09606 intact-crc:10423484AC3552BB|rigid:rIzwGyqxbX4jKGWe5JqgVRGr7y8 false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q3V5L5 uniprotkb:P09022 intact:EBI-3957727|uniprotkb:Q6P3S8|uniprotkb:Q6P6B3|uniprotkb:Q766X5|uniprotkb:Q76D04|uniprotkb:Q96LS2|ensembl:ENSP00000456037 intact:EBI-3957603|uniprotkb:P15463 psi-mi:mgt5b_human(display_long)|uniprotkb:MGAT5B(gene name)|psi-mi:MGAT5B(display_short)|uniprotkb:KIAA2008(gene name synonym)|uniprotkb:Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B(gene name synonym)|uniprotkb:GlcNAc-T Vb(gene name synonym)|uniprotkb:Mannoside acetylglucosaminyltransferase 5B(gene name synonym)|uniprotkb:N-acetylglucosaminyl-transferase Vb(gene name synonym)|uniprotkb:N-acetylglucosaminyltransferase IX(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958739|imex:IM-15418-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186101.1|refseq:NP_653278.2|refseq:NP_945193.1|ensembl:ENSG00000167889(gene)|ensembl:ENST00000569840(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018242"(protein O-linked glycosylation via serine)|go:"GO:0030144"(alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0030145"(manganese ion binding)|interpro:IPR026116 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:YQ7JoeC1hwjfy03NcnLBLmdZhxc9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:5DF4C3ECAC48A8E3|rigid:CVWhx0g1rwyzvX5fY7DlXsWQpbg false nYFP:?-? cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q6UY14 uniprotkb:P09022 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 intact:EBI-3957603|uniprotkb:P15463 psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958721|imex:IM-15418-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:9AE94FAAC7FFA800|rigid:o/xg+wr5ecYpgLNUx2n2fFZxP54 false nYFP:?-? cYFP:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q6PEX3 uniprotkb:P09022 intact:EBI-3957672|ensembl:ENSP00000353742|uniprotkb:B0RZD3 intact:EBI-3957603|uniprotkb:P15463 psi-mi:kr261_human(display_long)|uniprotkb:KRTAP26-1(gene name)|psi-mi:KRTAP26-1(display_short)|uniprotkb:KAP26.1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958701|imex:IM-15418-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197683(gene)|ensembl:ENST00000360542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|refseq:NP_981950.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:VKgQPRg2qO2FXQx0fQ/dd/5kMws9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:A0BBD002097424B1|rigid:+tRqTru/+wWQvtNEztE7QbHEDaY false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q5JSZ5 uniprotkb:P09022 intact:EBI-744891|uniprotkb:Q66VZ2|uniprotkb:Q9H683|uniprotkb:Q5JSZ7|uniprotkb:O60270|intact:EBI-2512629|intact:EBI-947989|uniprotkb:Q68CR0|intact:EBI-2559356|uniprotkb:Q96EI9|ensembl:ENSP00000508005|ensembl:ENSP00000508048 intact:EBI-3957603|uniprotkb:P15463 psi-mi:prc2b_human(display_long)|uniprotkb:PRRC2B(gene name)|psi-mi:PRRC2B(display_short)|uniprotkb:HLA-B-associated transcript 2-like 1(gene name synonym)|uniprotkb:KIAA0515(gene name synonym)|uniprotkb:BAT2L(gene name synonym)|uniprotkb:BAT2L1(gene name synonym)|uniprotkb:Proline-rich coiled-coil protein 2B(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958767|imex:IM-15418-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037450.2|ensembl:ENST00000682501|ensembl:ENSP00000508073|ensembl:ENSP00000508048|ensembl:ENSP00000508005|ensembl:ENSG00000288701(gene)|ensembl:ENST00000683519(transcript)|ensembl:ENST00000684596(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:Q5JSZ5 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:N1MgJl3k+WJTF+XUf5VFIB06B909606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:49E1D23BA0A69176|rigid:+H83/W9rM/ryTyGwtQDdQtO/9cU false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q6P1W5 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958723|imex:IM-15418-126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496 - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 intact-crc:49E556AC8817C7B3|rigid:JA6v6Nq+/PiH5MIpGCqvJ36GMts false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q8N448 uniprotkb:P09022 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 intact:EBI-3957603|uniprotkb:P15463 psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958759|imex:IM-15418-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:B3E9D9BF5C6ABCAB|rigid:WPlOS7yj6az6g2bDYymm9av5md4 false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P49639 uniprotkb:P09022 intact:EBI-740785|uniprotkb:O43363|uniprotkb:B2R8U7|uniprotkb:A4D184 intact:EBI-3957603|uniprotkb:P15463 psi-mi:hxa1_human(display_long)|uniprotkb:Homeobox protein Hox-1F(gene name synonym)|uniprotkb:HOXA1(gene name)|psi-mi:HOXA1(display_short)|uniprotkb:HOX1F(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958715|imex:IM-15418-122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005513.1|refseq:NP_705873.2|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|reactome:R-HSA-5617472|mint:P49639 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:QjQVU0uonSpj5vQU0pgzXuXmW3Y9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:EF47E279B0B15EB9|rigid:DI8lXIALke+tL4XULOfKvdXbXuc false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q9BSW2 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-739773|uniprotkb:B4E1X0|uniprotkb:B9EK63|ensembl:ENSP00000409382 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:efc4b_human(display_long)|uniprotkb:CRACR2A(gene name)|psi-mi:CRACR2A(display_short)|uniprotkb:Calcium release-activated calcium channel regulator 2A(gene name synonym)|uniprotkb:Calcium release-activated channel regulator 2A(gene name synonym)|uniprotkb:EFCAB4B(gene name synonym)|uniprotkb:RAB46(gene name synonym)|uniprotkb:Ras-related protein Rab-46(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958769|imex:IM-15418-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001138430.1|refseq:NP_116069.1|ensembl:ENSG00000130038(gene)|ensembl:ENST00000440314(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001772"(immunological synapse)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031982"(vesicle)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0034776"(response to histamine)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051928"(positive regulation of calcium ion transport)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:6PSD|reactome:R-HSA-6798695|interpro:IPR027417 go:"GO:0005634"(nucleus)|go:"GO:0031982"(vesicle) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2021/04/12 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:IjhHTze6Dftzv9JltvNQgdATG+89606 intact-crc:10ED0B6BA4072D2B|rigid:IEIDvypss8pGlp9+6hY5OkcNJ9I false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q9UHV8 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3957707|ensembl:ENSP00000221797|uniprotkb:C5HZ15 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pp13_human(display_long)|uniprotkb:LGALS13(gene name)|psi-mi:LGALS13(display_short)|uniprotkb:PLAC8(gene name synonym)|uniprotkb:Galectin-13(gene name synonym)|uniprotkb:Placental tissue protein 13(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958725|imex:IM-15418-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000105198(gene)|ensembl:ENST00000221797(transcript)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030653|interpro:IPR044156|rcsb pdb:1F87|rcsb pdb:5XG7|rcsb pdb:5XG8|rcsb pdb:5Y03|rcsb pdb:6A62|rcsb pdb:6A63|rcsb pdb:6A64|rcsb pdb:6A65|rcsb pdb:6A66|rcsb pdb:6KJW|rcsb pdb:6KJX|rcsb pdb:6KJY|refseq:NP_037400.1 go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031982"(vesicle) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:V4UZbFLEBFoDqXzyLe4a0O+PO3g9606 intact-crc:109683EC0C58558D|rigid:/ug9MNxOYCTG7fXkVqdP+Ukh+Rc false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:O15294 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958771|imex:IM-15418-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 intact-crc:783A4486E19FE550|rigid:dzvvtyqbeRiuPlX45MnfkofUxMg false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q8IYX7 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958743|imex:IM-15418-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1 go:"GO:0031982"(vesicle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606 intact-crc:A2D6A2BD41563B0D|rigid:MzOQaB/yKNHRVVYNRKGj9ShgCK4 false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:O60711 uniprotkb:P09022 intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512 intact:EBI-3957603|uniprotkb:P15463 psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958791|imex:IM-15418-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137467.1|refseq:NP_001294880.1|refseq:NP_004802.1|ensembl:ENSG00000110031(gene)|ensembl:ENST00000395074(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042995"(cell projection)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050859"(negative regulation of B cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0031982"(vesicle)|go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:B807F25C65142CB5|rigid:PZp9VeX4JXOQHLdoeUjYd7h9R04 false nYFP:?-? cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q92802 uniprotkb:P09022 intact:EBI-2514973|uniprotkb:A3KME8|ensembl:ENSP00000267068|ensembl:ENSP00000501416|ensembl:ENSP00000501516|ensembl:ENSP00000501518|ensembl:ENSP00000501537 intact:EBI-3957603|uniprotkb:P15463 psi-mi:n42l2_human(display_long)|uniprotkb:N4BP2L2(gene name)|psi-mi:N4BP2L2(display_short)|uniprotkb:CG005(gene name synonym)|uniprotkb:PFAAP5(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 5(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958789|imex:IM-15418-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016875836.1|refseq:XP_016875837.1|refseq:XP_016875838.1|refseq:NP_055702.1|ensembl:ENSG00000244754(gene)|ensembl:ENST00000267068(transcript)|ensembl:ENST00000674349(transcript)|ensembl:ENST00000674421(transcript)|ensembl:ENST00000674465(transcript)|ensembl:ENST00000674484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001824"(blastocyst development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|interpro:IPR026302|interpro:IPR026568|interpro:IPR027417|mint:Q92802 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:a7wRNCzoB/ImcDT7U8E5355qX1A9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:BA9799538AF273EA|rigid:C3qs3hvRC9NhKAXx0BgYB2VwXmE false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q5TD97 uniprotkb:P09022 intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357 intact:EBI-3957603|uniprotkb:P15463 psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958717|imex:IM-15418-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:7AE0957FCE89F3E9|rigid:19VluwKsHUOkVToriC65dzZh9hM false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:O15162 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958765|imex:IM-15418-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1 go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 intact-crc:CF53CB7B8D701ABA|rigid:dQLrrmwZjqps8IQmsWKrnhcZkyA false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9NRQ2 uniprotkb:P09022 intact:EBI-769257|uniprotkb:Q2TTR3|uniprotkb:Q658L3|uniprotkb:Q7Z505|uniprotkb:A8K2E9|uniprotkb:Q6ZR73|ensembl:ENSP00000347038|ensembl:ENSP00000399315|ensembl:ENSP00000419040 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pls4_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 4"(gene name synonym)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 43 protein(gene name synonym)|uniprotkb:PLSCR4(gene name)|psi-mi:PLSCR4(display_short)|uniprotkb:GIG43(orf name) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958747|imex:IM-15418-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005247711.1|refseq:XP_005247712.1|refseq:NP_001121778.1|refseq:NP_001170775.1|refseq:NP_065086.2|refseq:NP_001121776.1|refseq:NP_001121777.1|refseq:XP_011511333.1|ensembl:ENSP00000347038|ensembl:ENST00000433593|ensembl:ENSP00000415605|ensembl:ENSP00000399315|ensembl:ENSP00000419040|ensembl:ENSG00000114698(gene)|ensembl:ENST00000354952(transcript)|ensembl:ENST00000446574(transcript)|ensembl:ENST00000493382(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR005552(Scramblase)|rcsb pdb:3Q5U go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:bqEhBoGZZebMZn4JWpg/X0qU49A9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:CB97018B37AD0EA1|rigid:YFq+B+CkMVK7CIIWWxAzw2sQLK0 false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9GZV8 uniprotkb:P09022 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-3957603|uniprotkb:P15463 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958773|imex:IM-15418-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031982"(vesicle) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:3F864F8121A9F562|rigid:Rpzld7W5kF8OR3Tyo1PaN5Cltbw false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9BYM8 uniprotkb:P09022 intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632 intact:EBI-3957603|uniprotkb:P15463 psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958757|imex:IM-15418-140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0031982"(vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:E5A405CB083F0369|rigid:zMfgpRgt74lZ2ez3i2DrL/OSDu8 false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q93062 uniprotkb:P09022 intact:EBI-740322|uniprotkb:Q92516|uniprotkb:Q92517|uniprotkb:Q92518|uniprotkb:Q96J26|uniprotkb:D3DSU9|ensembl:ENSP00000318102|ensembl:ENSP00000380486 intact:EBI-3957603|uniprotkb:P15463 psi-mi:rbpms_human(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958763|imex:IM-15418-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008710.1|refseq:NP_001008711.1|refseq:NP_001008712.1|refseq:NP_006858.1|ensembl:ENSG00000157110(gene)|ensembl:ENST00000320203(transcript)|ensembl:ENST00000397323(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q93062|rcsb pdb:1BNY|rcsb pdb:5CYJ|rcsb pdb:5DET|refseq:XP_016868475.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0031982"(vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:3PsLJDzqs+19eVFeQlN+yLielYM9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:B8C67CC4DA2F516C|rigid:0yldLlCXvM+RYIG6O/Tv5XAaOwo false nYFP:?-? cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:O76081 uniprotkb:P09022 intact:EBI-1052678|uniprotkb:Q96BG9|ensembl:ENSP00000297313 intact:EBI-3957603|uniprotkb:P15463 psi-mi:rgs20_human(display_long)|uniprotkb:Regulator of Gz-selective protein signaling 1(gene name synonym)|uniprotkb:Gz-selective GTPase-activating protein(gene name synonym)|uniprotkb:RGS20(gene name)|psi-mi:RGS20(display_short)|uniprotkb:RGSZ1(gene name synonym)|uniprotkb:ZGAP1(gene name synonym)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958709|imex:IM-15418-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003693.2|refseq:NP_733466.1|refseq:NP_001273602.1|refseq:NP_001273603.1|refseq:NP_001273604.1|ensembl:ENSG00000147509(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036305|mint:O76081|reactome:R-HSA-418594|reactome:R-HSA-418597|ensembl:ENST00000297313(transcript)|refseq:XP_011515924.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:ZGGorrcKaXGhS8ds2O+UE5TY13Y9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:E2E5BB78F42E65A1|rigid:CtKeXQ9B6wUi0/zDPZB9OgEmHuE false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:O43609 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3866665|uniprotkb:Q6PNE0|uniprotkb:D3DNX6|ensembl:ENSP00000343785|ensembl:ENSP00000377871|ensembl:ENSP00000480540|ensembl:ENSP00000481675|ensembl:ENSP00000498292 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:spy1_human(display_long)|uniprotkb:SPRY1(gene name)|psi-mi:SPRY1(display_short) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958737|imex:IM-15418-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_005832.1|refseq:NP_955359.1|refseq:NP_001244967.1|refseq:NP_001244968.1|refseq:XP_005262743.1|ensembl:ENSG00000164056(gene)|ensembl:ENST00000339241(transcript)|ensembl:ENST00000394339(transcript)|ensembl:ENST00000610581(transcript)|ensembl:ENST00000622283(transcript)|ensembl:ENST00000651917(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001759"(organ induction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR007875(Sprouty)|interpro:IPR030783|mint:O43609|reactome:R-HSA-182971|refseq:XP_016863124.1 go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|go:"GO:0031982"(vesicle) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:tbucIEQYibDQbBC1xVIZVDH2nIY9606 intact-crc:6B180DA08AC23C2D|rigid:17hz9c6JSYPpHbODvpoexfAcMAE false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q13077 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958707|imex:IM-15418-118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956 go:"GO:0031982"(vesicle)|go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606 intact-crc:54B367CC628608EF|rigid:sYRqrzAd2DAJAePs/4hW68X8kUg false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q12933 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958755|imex:IM-15418-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N go:"GO:0031982"(vesicle)|go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 intact-crc:4A72882948E36F82|rigid:nWSG5dOw+fIqrzwbTd5yjJhVlGI false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q05516 uniprotkb:P09022 intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4 intact:EBI-3957603|uniprotkb:P15463 psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958741|imex:IM-15418-134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus)|go:"GO:0031982"(vesicle) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:DFD46B9C6362F91B|rigid:VHydg89Xjz1vQWvxhClE7OVMx+M false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9Y2Y4 uniprotkb:P09022 intact:EBI-954098|ensembl:ENSP00000376035|ensembl:ENSP00000262630|uniprotkb:Q8WVP2 intact:EBI-3957603|uniprotkb:P15463 psi-mi:zbt32_human(display_long)|uniprotkb:Fanconi anemia zinc finger protein(gene name synonym)|uniprotkb:Testis zinc finger protein(gene name synonym)|uniprotkb:FANCC-interacting protein(gene name synonym)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)|uniprotkb:FAZF(gene name synonym)|uniprotkb:TZFP(gene name synonym)|uniprotkb:ZNF538(gene name synonym)|uniprotkb:Zinc finger protein 538(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958779|imex:IM-15418-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000262630(transcript)|ensembl:ENST00000392197(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:3M5B|ensembl:ENSG00000011590(gene)|refseq:NP_055198.1|refseq:NP_001303831.1|refseq:NP_001303832.1|refseq:XP_011525020.1|refseq:XP_016882078.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:gAas4U/RF96mVnqIK9dlhZ55zEY9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:A6D66233C9ADE1EF|rigid:Tt1gQtQdFKmzZI8wdl9FVfxQCG0 false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q15654 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958745|imex:IM-15418-136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:B350FD041504BA93|rigid:1rY6hGt3dCeM1tjWrvEWY5WudgE false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q9BYR7 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-751260|ensembl:ENSP00000375429|ensembl:ENSP00000459215 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:kra32_human(display_long)|uniprotkb:Keratin-associated protein 3.2(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 3.2(gene name synonym)|uniprotkb:KRTAP3-2(gene name)|psi-mi:KRTAP3-2(display_short)|uniprotkb:KAP3.2(gene name synonym)|uniprotkb:KRTAP3.2(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958753|imex:IM-15418-138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_114165.1|ensembl:ENSG00000212900(gene)|ensembl:ENSG00000263296(gene)|ensembl:ENST00000391587(transcript)|ensembl:ENST00000575409(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR007659(Keratin, high-sulphur matrix protein)|reactome:R-HSA-6805567 go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:2AFUGT7g1vlyF9kv3x5NYu/bv9c9606 intact-crc:DC2727DDFC40B93B|rigid:7bWj7H0z/0AHInJVwHS+cc+P93M false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:O75865 uniprotkb:P09022 intact:EBI-743573|uniprotkb:Q9BQ45|uniprotkb:Q9P092|uniprotkb:K7ERB1|uniprotkb:K7ERQ4|ensembl:ENSP00000468612 intact:EBI-3957603|uniprotkb:P15463 psi-mi:tpc6a_human(display_long)|uniprotkb:TRAPPC6A(gene name)|psi-mi:TRAPPC6A(display_short)|uniprotkb:HSPC289(orf name) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958713|imex:IM-15418-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077013.1|refseq:NP_001257821.1|refseq:NP_001257822.1|refseq:NP_001257820.1|ensembl:ENSG00000007255(gene)|ensembl:ENST00000585934(transcript)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR037992|mint:O75865|rcsb pdb:2C0J|rcsb pdb:2J3T|reactome:R-HSA-204005|reactome:R-HSA-8876198|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:1903232"(melanosome assembly)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR024096|dip:DIP-37869N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:fj7bq0NxA91fevb0Iu/0+Hx05Tk9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:D76C8D233F08656A|rigid:48mP1BP/ijxEz8fLaNfpanLI4NI false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9UKS7 uniprotkb:P09022 intact:EBI-3893057|uniprotkb:Q53YJ5|uniprotkb:Q6PQC5|uniprotkb:Q6PQC6|uniprotkb:Q6PQC7|uniprotkb:Q6PQC8|uniprotkb:Q6PQD0|uniprotkb:Q6PQD1|uniprotkb:Q8N6S1|ensembl:ENSP00000412869 intact:EBI-3957603|uniprotkb:P15463 psi-mi:ikzf2_human(display_long)|uniprotkb:IKZF2(gene name)|psi-mi:IKZF2(display_short)|uniprotkb:HELIOS(gene name synonym)|uniprotkb:ZNFN1A2(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 2(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958719|imex:IM-15418-124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016859078.1|refseq:XP_016859079.1|refseq:XP_011509116.1|refseq:NP_001072994.1|refseq:NP_057344.2|refseq:XP_005246441.1|refseq:XP_005246442.1|ensembl:ENSG00000030419(gene)|ensembl:ENST00000434687(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:7LPS go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:2NKseBTmX2D5I+x4feYj+RdpPIc9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:325BDE800FE0D1D9|rigid:PR/PlNuNdJl38am3yoCRRlqfPvk false nYFP:?-? cYFP:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q14533 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-739648|uniprotkb:Q14846|uniprotkb:Q16274|uniprotkb:Q8WU52|uniprotkb:Q9BR74|uniprotkb:Q17R48|ensembl:ENSP00000369349 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:krt81_human(display_long)|uniprotkb:Type II hair keratin Hb1(gene name synonym)|uniprotkb:ghHKb1(gene name synonym)|uniprotkb:Keratin-81(gene name synonym)|uniprotkb:Type-II keratin Kb21(gene name synonym)|uniprotkb:Hair keratin K2.9(gene name synonym)|uniprotkb:KRT81(gene name)|psi-mi:KRT81(display_short)|uniprotkb:KRTHB1(gene name synonym)|uniprotkb:MLN137(gene name synonym)|uniprotkb:Keratin, hair, basic, 1(gene name synonym)|uniprotkb:Metastatic lymph node 137 gene protein(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958731|imex:IM-15418-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_002272.2|ensembl:ENST00000327741(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR003054(Type II keratin)|ensembl:ENSG00000205426(gene)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:Y/1YhLCN54gK8DZQyc4OqfNDwAs9606 intact-crc:BD27C73E6E9D28D9|rigid:hQ6G9SGp5TWD9pVdKa+WAw8RUDU false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q99697 uniprotkb:P09022 intact:EBI-1175211|uniprotkb:O60578|uniprotkb:O60579|uniprotkb:O60580|uniprotkb:Q9BY17|ensembl:ENSP00000347004|ensembl:ENSP00000378095|ensembl:ENSP00000481951|ensembl:ENSP00000484763|uniprotkb:B2RA02|uniprotkb:B3KXS0|uniprotkb:Q3KQX9|uniprotkb:A8K6C6 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pitx2_human(display_long)|uniprotkb:RIEG bicoid-related homeobox transcription factor(gene name synonym)|uniprotkb:Solurshin(gene name synonym)|uniprotkb:ALL1-responsive protein ARP1(gene name synonym)|uniprotkb:PITX2(gene name)|psi-mi:PITX2(display_short)|uniprotkb:ARP1(gene name synonym)|uniprotkb:RGS(gene name synonym)|uniprotkb:RIEG(gene name synonym)|uniprotkb:RIEG1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 2(gene name synonym)|uniprotkb:Homeobox protein PITX2(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958787|imex:IM-15418-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164093(gene)|ensembl:ENST00000354925(transcript)|ensembl:ENST00000394595(transcript)|ensembl:ENST00000613094(transcript)|ensembl:ENST00000614423(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_000316.2|refseq:NP_001191326.1|refseq:NP_001191327.1|refseq:NP_001191328.1|refseq:NP_700475.1|refseq:NP_700476.1|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035993"(deltoid tuberosity development)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060126"(somatotropin secreting cell differentiation)|go:"GO:0060127"(prolactin secreting cell differentiation)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061325"(cell proliferation involved in outflow tract morphogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0070986"(left/right axis specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|mint:Q99697|rcsb pdb:2L7F|rcsb pdb:2L7M|rcsb pdb:2LKX|reactome:R-HSA-8866906|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|refseq:XP_011530329.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:JWKFsTNDJOefVhq9VKgHa4A1C8g9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:A5E7BDD755600F56|rigid:1fnsUKyWcmsZXI0ypmDSG82nkTs false nYFP:c-c cYFP:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q14088 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-744685|uniprotkb:Q5JUZ6|uniprotkb:Q92465|ensembl:ENSP00000257017 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:rb33a_human(display_long)|uniprotkb:Small GTP-binding protein S10(gene name synonym)|uniprotkb:RAB33A(gene name)|psi-mi:RAB33A(display_short)|uniprotkb:RABS10(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958703|imex:IM-15418-116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_004785.1|interpro:IPR041822|reactome:R-HSA-8854214|reactome:R-HSA-8873719|interpro:IPR027417|ensembl:ENSG00000134594(gene)|ensembl:ENST00000257017(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0032482"(Rab protein signal transduction)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein) go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:E97stXWvkGPUamSzsiejNoY4S789606 intact-crc:58F1E645CC3F4C70|rigid:pnAZJByddiNUTUZOKZZkeBdSYlY false cYFP:c-c nYFP:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q99750 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958727|imex:IM-15418-128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 go:"GO:0005737"(cytoplasm)|go:"GO:0031982"(vesicle)|go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:5CEA3CC2C0B2BE63|rigid:at9hvSvvP0EwtxLD5KgIEI02V9w false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P48059 uniprotkb:P09022 intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907 intact:EBI-3957603|uniprotkb:P15463 psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958761|imex:IM-15418-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005634"(nucleus) - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:C92DC42F12C542B1|rigid:/JqGGP3ZdwXBQr9+opRFwGb3R8A false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q8WUM4 uniprotkb:P09022 intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290 intact:EBI-3957603|uniprotkb:P15463 psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958777|imex:IM-15418-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:001146A7F0BA0457|rigid:SlWyiNr6IgXrL0SAA+W3ojdASy8 false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:P26371 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-3958099|ensembl:ENSP00000431443|uniprotkb:Q14564|uniprotkb:Q3MIP8 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:kra59_human(display_long)|uniprotkb:KRTAP5-9(gene name)|psi-mi:KRTAP5-9(display_short)|uniprotkb:KAP5.9(gene name synonym)|uniprotkb:KRN1(gene name synonym)|uniprotkb:KRTAP5.9(gene name synonym)|uniprotkb:UHSK1(gene name synonym)|uniprotkb:Keratin, cuticle, ultrahigh sulfur 1(gene name synonym)|uniprotkb:Keratin, ultra high-sulfur matrix protein A(gene name synonym)|uniprotkb:Keratin-associated protein 5.9(gene name synonym)|uniprotkb:UHS keratin A(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 5.9(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958785|imex:IM-15418-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N ensembl:ENSG00000254997(gene)|ensembl:ENST00000528743(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|mint:P26371|reactome:R-HSA-6805567|refseq:NP_005544.4 go:"GO:0031982"(vesicle)|go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:B6s6+/WKO8MfrhEgj4xz7BH/jqE9606 intact-crc:E34541F7FF48BF31|rigid:q2Fk9tSUOmpCl2nbQPkTNcd1SBM false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9BQ66 uniprotkb:P09022 intact:EBI-739863|uniprotkb:A3KMC5|uniprotkb:Q495I0|ensembl:ENSP00000377582|ensembl:ENSP00000458979 intact:EBI-3957603|uniprotkb:P15463 psi-mi:kr412_human(display_long)|uniprotkb:KRTAP4-12(gene name)|psi-mi:KRTAP4-12(display_short)|uniprotkb:KAP4.12(gene name synonym)|uniprotkb:KRTAP4.12(gene name synonym)|uniprotkb:Keratin-associated protein 4.12(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.12(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958729|imex:IM-15418-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_114060.1|ensembl:ENSG00000213416(gene)|ensembl:ENSG00000263236(gene)|ensembl:ENST00000394014(transcript)|ensembl:ENST00000571271(transcript)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:XLiYOwNd549kn287BJWgx5zmDCY9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:20023FB690080D2B|rigid:Pp8J7VVSdTbDv3iuHVR1MspOhUc false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P09022 uniprotkb:Q8IYH5 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958705|imex:IM-15418-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 intact-crc:529C73827B72CCDF|rigid:DoCgQ9Ez3pkuQbvtnJxZNOBOF8g false cYFP:c-c nYFP:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q96GS6 uniprotkb:P09022 intact:EBI-2870273|uniprotkb:Q6PJU2|uniprotkb:A8K0G8|uniprotkb:Q9BWL0|uniprotkb:Q8WUH9|uniprotkb:Q9H7Q9|uniprotkb:D6W5Z9|ensembl:ENSP00000292577|ensembl:ENSP00000504042 intact:EBI-3957603|uniprotkb:P15463 psi-mi:ab17a_human(display_long)|uniprotkb:ABHD17A(gene name)|psi-mi:ABHD17A(display_short)|uniprotkb:C19orf27(gene name synonym)|uniprotkb:FAM108A1(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3958783|imex:IM-15418-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011526640.1|refseq:XP_016882830.1|refseq:NP_001123583.1|refseq:NP_112490.3|ensembl:ENSG00000129968(gene)|ensembl:ENST00000292577(transcript)|ensembl:ENST00000676686(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0010008"(endosome membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099033"(anchored component of postsynaptic recycling endosome membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1905668"(positive regulation of protein localization to endosome)|interpro:IPR022742|interpro:IPR029058|mint:Q96GS6|reactome:R-HSA-9648002|go:"GO:0016020"(membrane) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:eZ6J8YENMgDhwA9IrEscvsGst+w9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:0BDCE23544268138|rigid:EzEjx6c5pAJw6ZVoRW6/PSNmZvo false nYFP:c-c cYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q13077 uniprotkb:P09022 intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183 intact:EBI-3957603|uniprotkb:P15463 psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym) psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6384519|imex:IM-15418-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N go:"GO:0031982"(vesicle)|go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2011/06/07 2014/10/16 rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 intact-crc:DC069BBBC37B00D1|rigid:sYRqrzAd2DAJAePs/4hW68X8kUg false glutathione s tranferase tag:?-? - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P09022 uniprotkb:P40424 intact:EBI-3957603|uniprotkb:P15463 intact:EBI-301611|uniprotkb:Q5T488|ensembl:ENSP00000405890|uniprotkb:B4DSC1|uniprotkb:F5H4U9 psi-mi:hxa1_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short)|uniprotkb:Era-1(gene name synonym)|uniprotkb:Hox-1.6(gene name synonym)|uniprotkb:Hoxa-1(gene name synonym)|uniprotkb:Early retinoic acid 1(gene name synonym)|uniprotkb:Homeobox protein Hox-1.6(gene name synonym)|uniprotkb:Homeoboxless protein ERA-1-399(gene name synonym)|uniprotkb:Homeotic protein ERA-1-993(gene name synonym) psi-mi:pbx1_human(display_long)|uniprotkb:PBX1(gene name)|psi-mi:PBX1(display_short)|uniprotkb:PRL(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)|uniprotkb:Homeobox protein PRL(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Lambert et al. (2012) imex:IM-15418|pubmed:23088713 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6384190|imex:IM-15418-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050890"(cognition)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060840"(artery development)|go:"GO:0060876"(semicircular canal formation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-59869N refseq:NP_001191892.1|refseq:NP_002576.1|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B72|go:"GO:0005634"(nucleus)|rcsb pdb:1PUF|reactome:R-HSA-452723|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|reactome:R-HSA-5617472|reactome:R-HSA-9013508|ensembl:ENSG00000185630(gene)|ensembl:ENST00000420696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|refseq:XP_005245286.1 go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031982"(vesicle) - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/06/07 2014/10/16 rogid:7acQzG5WkQgd2Iz1O5PGLrJOkXI10090 rogid:YViNj+q9A6e+VCAkMUQowMzvowE9606 intact-crc:93FB9B088FD273EF|rigid:ZLM4N30dnGpz3sXkgAVn1qcbcls false cYFP:c-c nYFP:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)