#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:A7GBG3	uniprotkb:P63027	intact:EBI-7604673|intact:MINT-8297602|ensemblbacteria:ABS41202|uniprotkb:Q79AH9	intact:EBI-520113|uniprotkb:P19065|ensembl:ENSP00000314214|uniprotkb:Q9BUC2	psi-mi:bxf_clobl(display_long)|uniprotkb:F(gene name)|psi-mi:F(display_short)|uniprotkb:Bontoxilysin-F(gene name synonym)|uniprotkb:boNT/F(gene name synonym)|uniprotkb:bont(gene name synonym)|uniprotkb:CLI_0851(locus name)	psi-mi:vamp2_human(display_long)|uniprotkb:Synaptobrevin-2(gene name synonym)|uniprotkb:VAMP2(gene name)|psi-mi:VAMP2(display_short)|uniprotkb:SYB2(gene name synonym)	psi-mi:"MI:0435"(protease assay)	Kalb et al. (2012)	pubmed:22172278|imex:IM-16752|mint:MINT-8297613|doi:10.1016/j.febslet.2011.11.033	taxid:441772(clobl)|taxid:441772("Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0194"(cleavage reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7604668|mint:MINT-8297663|imex:IM-16752-1	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011987710.1|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR012500(Clostridium neurotoxin, translocation)|ensemblbacteria:ABS41202(transcript)|ensemblbacteria:CLI_0851(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0044156"(host cell junction)|go:"GO:0044161"(host cell cytoplasmic vesicle)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044231"(host cell presynaptic membrane)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0090729"(toxin activity)|interpro:IPR036248|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3FUQ|rcsb pdb:3RSJ|mint:MINT-8297665(identity)	refseq:NP_055047.2|ensembl:ENSG00000220205(gene)|ensembl:ENST00000316509(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043621"(protein self-association)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061025"(membrane fusion)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070083"(clathrin-sculpted monoamine transport vesicle membrane)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855|mint:P63027|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|reactome:R-HSA-1445148|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-199992|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-449836|reactome:R-HSA-5250955|reactome:R-HSA-5250958|reactome:R-HSA-5250981|reactome:R-HSA-5250982|reactome:R-HSA-5250989|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|dip:DIP-39072N|mint:MINT-8297666(identity)	-	comment:mint	-	figure legend:f1a f1b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:PUSLjCpFP271xW5Us+YdTAAnC/8441772	rogid:uuuJXsI5sr7fzjxuBhSYDHJZp9M9606	intact-crc:4D6CA741091DA454|rigid:t1/kceteUm9Je77UKWw96yRik4Y	false	glutathione s tranferase tag:?-?(MINT-8297668)	uncategorized protein modification:58-59(MINT-8297675)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:D2KHQ9	uniprotkb:P63027	intact:EBI-7604762|intact:MINT-8297604	intact:EBI-520113|uniprotkb:P19065|ensembl:ENSP00000314214|uniprotkb:Q9BUC2	psi-mi:d2khq9_clobo(display_long)	psi-mi:vamp2_human(display_long)|uniprotkb:Synaptobrevin-2(gene name synonym)|uniprotkb:VAMP2(gene name)|psi-mi:VAMP2(display_short)|uniprotkb:SYB2(gene name synonym)	psi-mi:"MI:0435"(protease assay)	Kalb et al. (2012)	pubmed:22172278|imex:IM-16752|mint:MINT-8297613|doi:10.1016/j.febslet.2011.11.033	taxid:1491(clobo)|taxid:1491(Clostridium botulinum)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0194"(cleavage reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7604813|mint:MINT-8297699|imex:IM-16752-3	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_021107080.1|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR012500(Clostridium neurotoxin, translocation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0090729"(toxin activity)|interpro:IPR036248|mint:MINT-8297705(identity)	refseq:NP_055047.2|ensembl:ENSG00000220205(gene)|ensembl:ENST00000316509(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043621"(protein self-association)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061025"(membrane fusion)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070083"(clathrin-sculpted monoamine transport vesicle membrane)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855|mint:P63027|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|reactome:R-HSA-1445148|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-199992|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-449836|reactome:R-HSA-5250955|reactome:R-HSA-5250958|reactome:R-HSA-5250981|reactome:R-HSA-5250982|reactome:R-HSA-5250989|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|dip:DIP-39072N|mint:MINT-8297701(identity)	-	comment:mint	-	comment:mint|figure legend:f2c f2d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:quu0HvEq0TNppW93skiJ98mmLmw1491	rogid:uuuJXsI5sr7fzjxuBhSYDHJZp9M9606	intact-crc:972ED9F799554182|rigid:5SE7JUCetv+tn0JD/NahXy85d3A	false	glutathione s tranferase tag:?-?(MINT-8297706)	binding-associated region:32-70(MINT-8297712)|uncategorized protein modification:58-59(MINT-8297702)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:D2KHQ9	uniprotkb:P63027	intact:EBI-7604762|intact:MINT-8297604	intact:EBI-520113|uniprotkb:P19065|ensembl:ENSP00000314214|uniprotkb:Q9BUC2	psi-mi:d2khq9_clobo(display_long)	psi-mi:vamp2_human(display_long)|uniprotkb:Synaptobrevin-2(gene name synonym)|uniprotkb:VAMP2(gene name)|psi-mi:VAMP2(display_short)|uniprotkb:SYB2(gene name synonym)	psi-mi:"MI:0435"(protease assay)	Kalb et al. (2012)	pubmed:22172278|imex:IM-16752|mint:MINT-8297613|doi:10.1016/j.febslet.2011.11.033	taxid:1491(clobo)|taxid:1491(Clostridium botulinum)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0194"(cleavage reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7604757|mint:MINT-8297679|imex:IM-16752-2	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_021107080.1|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR012500(Clostridium neurotoxin, translocation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0090729"(toxin activity)|interpro:IPR036248|mint:MINT-8297681(identity)	refseq:NP_055047.2|ensembl:ENSG00000220205(gene)|ensembl:ENST00000316509(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043621"(protein self-association)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061025"(membrane fusion)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070083"(clathrin-sculpted monoamine transport vesicle membrane)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855|mint:P63027|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|reactome:R-HSA-1445148|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-199992|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-449836|reactome:R-HSA-5250955|reactome:R-HSA-5250958|reactome:R-HSA-5250981|reactome:R-HSA-5250982|reactome:R-HSA-5250989|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|dip:DIP-39072N|mint:MINT-8297685(identity)	-	comment:mint	-	figure legend:f2a f2b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:quu0HvEq0TNppW93skiJ98mmLmw1491	rogid:uuuJXsI5sr7fzjxuBhSYDHJZp9M9606	intact-crc:FF878DA94967169E|rigid:5SE7JUCetv+tn0JD/NahXy85d3A	false	glutathione s tranferase tag:?-?(MINT-8297682)	uncategorized protein modification:58-59(MINT-8297686)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:A7GBG3	uniprotkb:P63027	intact:EBI-7604673|intact:MINT-8297602|ensemblbacteria:ABS41202|uniprotkb:Q79AH9	intact:EBI-520113|uniprotkb:P19065|ensembl:ENSP00000314214|uniprotkb:Q9BUC2	psi-mi:bxf_clobl(display_long)|uniprotkb:F(gene name)|psi-mi:F(display_short)|uniprotkb:Bontoxilysin-F(gene name synonym)|uniprotkb:boNT/F(gene name synonym)|uniprotkb:bont(gene name synonym)|uniprotkb:CLI_0851(locus name)	psi-mi:vamp2_human(display_long)|uniprotkb:Synaptobrevin-2(gene name synonym)|uniprotkb:VAMP2(gene name)|psi-mi:VAMP2(display_short)|uniprotkb:SYB2(gene name synonym)	psi-mi:"MI:0435"(protease assay)	Kalb et al. (2012)	pubmed:22172278|imex:IM-16752|mint:MINT-8297613|doi:10.1016/j.febslet.2011.11.033	taxid:441772(clobl)|taxid:441772("Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0194"(cleavage reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7604871|mint:MINT-8297715|imex:IM-16752-4	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011987710.1|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR012500(Clostridium neurotoxin, translocation)|ensemblbacteria:ABS41202(transcript)|ensemblbacteria:CLI_0851(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0044156"(host cell junction)|go:"GO:0044161"(host cell cytoplasmic vesicle)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044231"(host cell presynaptic membrane)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0090729"(toxin activity)|interpro:IPR036248|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3FUQ|rcsb pdb:3RSJ|mint:MINT-8297723(identity)	refseq:NP_055047.2|ensembl:ENSG00000220205(gene)|ensembl:ENST00000316509(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043621"(protein self-association)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061025"(membrane fusion)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070083"(clathrin-sculpted monoamine transport vesicle membrane)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855|mint:P63027|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|reactome:R-HSA-1445148|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-199992|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-449836|reactome:R-HSA-5250955|reactome:R-HSA-5250958|reactome:R-HSA-5250981|reactome:R-HSA-5250982|reactome:R-HSA-5250989|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|dip:DIP-39072N|mint:MINT-8297717(identity)	-	comment:mint	-	figure legend:f1c f1d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:PUSLjCpFP271xW5Us+YdTAAnC/8441772	rogid:uuuJXsI5sr7fzjxuBhSYDHJZp9M9606	intact-crc:D87A0292C7524316|rigid:t1/kceteUm9Je77UKWw96yRik4Y	false	glutathione s tranferase tag:?-?(MINT-8297724)	binding-associated region:32-70(MINT-8297718)|uncategorized protein modification:58-59(MINT-8297720)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)