#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8BYR5 uniprotkb:Q9JKK1 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 intact:EBI-3869466|uniprotkb:Q9D3A1|uniprotkb:Q9D729|ensembl:ENSMUSP00000027743 psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:stx6_mouse(display_long)|uniprotkb:Stx6(gene name)|psi-mi:Stx6(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7569356|mint:MINT-8292315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8293078(identity) refseq:NP_067408.1|ensembl:ENSMUSG00000026470(gene)|ensembl:ENSMUST00000027743(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1903827"|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015260(Syntaxin 6, N-terminal)|mint:Q9JKK1|reactome:R-MMU-6811438|reactome:R-MMU-6811440|mint:MINT-8292317(identity) go:"GO:0005802"(trans-Golgi network) comment:mint - figure legend:f1|comment:domino|comment:mint taxid:10090(mouse-alpha t3-1)|taxid:10090(Mus musculus) - 2011/11/15 2014/10/16 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 rogid:gqo74psGPV6QSsFaqX9cLCSdAbc10090 intact-crc:6443A6F50A226C1B|rigid:iPacRBvCIhyaZghnKMujsSXvrBI false binding-associated region:491-594,370-451(IPR000008)|tandem tag:?-?(MINT-8293092) - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8BYR5 uniprotkb:Q921M4 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 intact:EBI-298519|ensembl:ENSMUSP00000109004|uniprotkb:A2AN43|uniprotkb:A2AN47 psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:goga2_mouse(display_long)|uniprotkb:Golga2(gene name)|psi-mi:Golga2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7569397|mint:MINT-8293823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8293826(identity) go:"GO:0019905"(syntaxin binding)|refseq:NP_001074437.1|ensembl:ENSMUSG00000002546(gene)|ensembl:ENSMUST00000113377(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051645"(Golgi localization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q921M4|reactome:R-MMU-162658|reactome:R-MMU-204005|reactome:R-MMU-6807878|reactome:R-MMU-9013148|reactome:R-MMU-9013405|refseq:XP_006498556.1|mint:MINT-8293825(identity) go:"GO:0005802"(trans-Golgi network) comment:mint - comment:domino|comment:mint|figure legend:sf1a sf1b sf1c taxid:10090(mouse-alpha t3-1)|taxid:10090(Mus musculus) - 2011/11/15 2014/10/16 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 rogid:GMrTr2bHQ0lyJ7MV2kNF5+7fhAk10090 intact-crc:5C7AE58F1EA679B4|rigid:WMxkNps0rqwgg5Heg0Dle1R4g2E false binding-associated region:491-594(MINT-8293836)|yellow fluorescent protein tag:?-?(MINT-8293833) - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining) uniprotkb:P84084 uniprotkb:Q9JKK1 intact:EBI-7569461|uniprotkb:P26437|intact:UNK-5383724|uniprotkb:A2RTC5|ensembl:ENSMUSP00000020717|ensembl:ENSMUSP00000127281 intact:EBI-3869466|uniprotkb:Q9D3A1|uniprotkb:Q9D729|ensembl:ENSMUSP00000027743 psi-mi:arf5_mouse(display_long)|uniprotkb:Arf5(gene name)|psi-mi:Arf5(display_short) psi-mi:stx6_mouse(display_long)|uniprotkb:Stx6(gene name)|psi-mi:Stx6(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7569455|mint:MINT-8293866 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031506.1|ensembl:ENSMUSG00000020440(gene)|ensembl:ENSMUST00000020717(transcript)|ensembl:ENSMUST00000169841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-MMU-6807878|reactome:R-MMU-6811434|mint:MINT-8293869(identity) refseq:NP_067408.1|ensembl:ENSMUSG00000026470(gene)|ensembl:ENSMUST00000027743(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1903827"|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015260(Syntaxin 6, N-terminal)|mint:Q9JKK1|reactome:R-MMU-6811438|reactome:R-MMU-6811440|mint:MINT-8293880(identity) go:"GO:0005794"(Golgi apparatus) function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint|comment:homomint - comment:homomint|comment:mint|figure legend:f8a f8b f8c taxid:10090(mouse-alpha t3-1)|taxid:10090(Mus musculus) - 2011/11/15 2014/10/16 rogid:da8exbGR3MGxZ6CPZqLvqJbyUYI10090 rogid:gqo74psGPV6QSsFaqX9cLCSdAbc10090 intact-crc:FA10E649B3C2CA67|rigid:d884FRDDreRiJ1NUyi8ukYSqEvA false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8BYR5 uniprotkb:Q9JKK1 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 intact:EBI-3869466|uniprotkb:Q9D3A1|uniprotkb:Q9D729|ensembl:ENSMUSP00000027743 psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:stx6_mouse(display_long)|uniprotkb:Stx6(gene name)|psi-mi:Stx6(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7569510|mint:MINT-8294259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8294264(identity) refseq:NP_067408.1|ensembl:ENSMUSG00000026470(gene)|ensembl:ENSMUST00000027743(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1903827"|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015260(Syntaxin 6, N-terminal)|mint:Q9JKK1|reactome:R-MMU-6811438|reactome:R-MMU-6811440|mint:MINT-8294262(identity) go:"GO:0005802"(trans-Golgi network) comment:mint - comment:mint|figure legend:f1p f1q f1r taxid:10090(mouse-alpha t3-1)|taxid:10090(Mus musculus) - 2011/11/15 2014/10/16 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 rogid:gqo74psGPV6QSsFaqX9cLCSdAbc10090 intact-crc:3EC9C50FAA950878|rigid:iPacRBvCIhyaZghnKMujsSXvrBI false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8BYR5 uniprotkb:O70480 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 intact:EBI-3871053|uniprotkb:Q9D095|ensembl:ENSMUSP00000114172|ensembl:ENSMUSP00000115133|ensembl:ENSMUSP00000116376 psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:vamp4_mouse(display_long)|uniprotkb:Vamp4(gene name)|psi-mi:Vamp4(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7569435|mint:MINT-8293847 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8293852(identity) refseq:NP_001334054.1|refseq:XP_006496997.1|ensembl:ENSMUSG00000026696(gene)|ensembl:ENSMUST00000135241(transcript)|ensembl:ENSMUST00000150040(transcript)|ensembl:ENSMUST00000155003(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042996"(regulation of Golgi to plasma membrane protein transport)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0099067"(integral component of presynaptic endosome membrane)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042855|interpro:IPR042887|mint:O70480|rcsb pdb:2NPS|reactome:R-MMU-6811440|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0071346"(cellular response to interferon-gamma)|mint:MINT-8293850(identity) go:"GO:0005802"(trans-Golgi network) comment:mint - comment:domino|comment:mint|figure legend:sf1d sf1e sf1f taxid:10090(mouse-alpha t3-1)|taxid:10090(Mus musculus) - 2011/11/15 2014/10/16 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 rogid:MYJbCkKQJuRwpXPK3kl+jsdUrjk10090 intact-crc:1288406F5BCF9F8A|rigid:XJDnZ3OARzD6DUVOW7CVkqqb0V8 false binding-associated region:491-594(MINT-8293853)|yellow fluorescent protein tag:?-?(MINT-8293855) - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8BYR5 uniprotkb:P84084 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 intact:EBI-7569461|uniprotkb:P26437|intact:UNK-5383724|uniprotkb:A2RTC5|ensembl:ENSMUSP00000020717|ensembl:ENSMUSP00000127281 psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:arf5_mouse(display_long)|uniprotkb:Arf5(gene name)|psi-mi:Arf5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7569528|mint:MINT-8293582 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8293585(identity) refseq:NP_031506.1|ensembl:ENSMUSG00000020440(gene)|ensembl:ENSMUST00000020717(transcript)|ensembl:ENSMUST00000169841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-MMU-6807878|reactome:R-MMU-6811434|mint:MINT-8293584(identity) - comment:mint function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint|comment:homomint figure legend:f3|comment:domino|comment:mint taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/11/15 2014/10/16 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 rogid:da8exbGR3MGxZ6CPZqLvqJbyUYI10090 intact-crc:5576FD906A3D9DB5|rigid:kB7bI1WjlhP3ZkjniSvfpciU5Es false binding-associated region:370-594(IPR000008)|ha tag:?-?(MINT-8293587) mutation increasing interaction:31-31(MINT-8293598)|flag tag:?-?(MINT-8293595) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BYR5 uniprotkb:P61750 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 intact:EBI-7569554|uniprotkb:Q9CXX3|uniprotkb:Q3TGC2|intact:MINT-1866425|uniprotkb:P36403|ensembl:ENSMUSP00000022429 psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:arf4_mouse(display_long)|uniprotkb:Arf4(gene name)|psi-mi:Arf4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7569625|mint:MINT-8293623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8293625(identity) refseq:NP_031505.1|ensembl:ENSMUSG00000021877(gene)|ensembl:ENSMUST00000022429(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61750|reactome:R-MMU-5620916|reactome:R-MMU-6807878|reactome:R-MMU-6811434|mint:MINT-8293633(identity) - comment:mint function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint figure legend:f3|comment:domino|comment:mint taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/11/15 2014/10/16 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 rogid:UQ8GuyD6go1ZCYpUU69uTevxoVo10090 intact-crc:CDFF8072E9187980|rigid:853VM5jtOFgulJvlqikmYutGfFA false binding-associated region:370-594(IPR000008)|ha tag:?-?(MINT-8293626) flag tag:?-?(MINT-8293636)|mutation increasing interaction:31-31(MINT-8293634) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61750 uniprotkb:Q8BYR5 intact:EBI-7569554|uniprotkb:Q9CXX3|uniprotkb:Q3TGC2|intact:MINT-1866425|uniprotkb:P36403|ensembl:ENSMUSP00000022429 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 psi-mi:arf4_mouse(display_long)|uniprotkb:Arf4(gene name)|psi-mi:Arf4(display_short) psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7569598|mint:MINT-8293603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031505.1|ensembl:ENSMUSG00000021877(gene)|ensembl:ENSMUST00000022429(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61750|reactome:R-MMU-5620916|reactome:R-MMU-6807878|reactome:R-MMU-6811434|mint:MINT-8293605(identity) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8293611(identity) - function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint comment:mint figure legend:f3|comment:domino|comment:mint taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/11/15 2014/10/16 rogid:UQ8GuyD6go1ZCYpUU69uTevxoVo10090 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 intact-crc:D79FAF4CF001DBD5|rigid:853VM5jtOFgulJvlqikmYutGfFA false flag tag:?-?(MINT-8293608)|mutation disrupting interaction:71-71(MINT-8293606) binding-associated region:370-594(IPR000008)|ha tag:?-?(MINT-8293616) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P84084 uniprotkb:Q8BYR5 intact:EBI-7569461|uniprotkb:P26437|intact:UNK-5383724|uniprotkb:A2RTC5|ensembl:ENSMUSP00000020717|ensembl:ENSMUSP00000127281 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 psi-mi:arf5_mouse(display_long)|uniprotkb:Arf5(gene name)|psi-mi:Arf5(display_short) psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7569728|mint:MINT-8293690 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031506.1|ensembl:ENSMUSG00000020440(gene)|ensembl:ENSMUST00000020717(transcript)|ensembl:ENSMUST00000169841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-MMU-6807878|reactome:R-MMU-6811434|mint:MINT-8293693(identity) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8293692(identity) - function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint|comment:homomint comment:mint figure legend:f5|comment:mint taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/11/15 2014/10/16 rogid:da8exbGR3MGxZ6CPZqLvqJbyUYI10090 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 intact-crc:B41D03490F8432CE|rigid:kB7bI1WjlhP3ZkjniSvfpciU5Es false mutation disrupting interaction:6-6(MINT-8293702)|flag tag:?-?(MINT-8293699) ha tag:?-?(MINT-8293695) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P84084 uniprotkb:Q8BYR5 intact:EBI-7569461|uniprotkb:P26437|intact:UNK-5383724|uniprotkb:A2RTC5|ensembl:ENSMUSP00000020717|ensembl:ENSMUSP00000127281 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 psi-mi:arf5_mouse(display_long)|uniprotkb:Arf5(gene name)|psi-mi:Arf5(display_short) psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7569651|mint:MINT-8293641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031506.1|ensembl:ENSMUSG00000020440(gene)|ensembl:ENSMUST00000020717(transcript)|ensembl:ENSMUST00000169841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-MMU-6807878|reactome:R-MMU-6811434|mint:MINT-8293643(identity) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8293649(identity) - function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint|comment:homomint comment:mint figure legend:f3|comment:domino|comment:mint taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/11/15 2014/10/16 rogid:da8exbGR3MGxZ6CPZqLvqJbyUYI10090 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 intact-crc:12F9D0896FED6326|rigid:kB7bI1WjlhP3ZkjniSvfpciU5Es false flag tag:?-?(MINT-8293646)|mutation disrupting interaction:71-71(MINT-8293644) ha tag:?-?(MINT-8293654)|binding-associated region:370-594(IPR000008) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BYR5 uniprotkb:P84084 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 intact:EBI-7569461|uniprotkb:P26437|intact:UNK-5383724|uniprotkb:A2RTC5|ensembl:ENSMUSP00000020717|ensembl:ENSMUSP00000127281 psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:arf5_mouse(display_long)|uniprotkb:Arf5(gene name)|psi-mi:Arf5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7569755|mint:MINT-8293663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8293666(identity) refseq:NP_031506.1|ensembl:ENSMUSG00000020440(gene)|ensembl:ENSMUST00000020717(transcript)|ensembl:ENSMUST00000169841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-MMU-6807878|reactome:R-MMU-6811434|mint:MINT-8293665(identity) - comment:mint function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint|comment:homomint figure legend:f4a|comment:mint taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2011/11/15 2014/10/16 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 rogid:da8exbGR3MGxZ6CPZqLvqJbyUYI10090 intact-crc:5DB16023A30413DD|rigid:kB7bI1WjlhP3ZkjniSvfpciU5Es false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BYR5 uniprotkb:P84084 intact:EBI-7569313|uniprotkb:Q6PCL7|uniprotkb:Q76I88|intact:MINT-8292694|uniprotkb:Q8K3K6|uniprotkb:Q80ZV8|uniprotkb:Q7TMM6|uniprotkb:Q66JM7|uniprotkb:O08903|uniprotkb:Q8BY04|uniprotkb:Q8BL25 intact:EBI-7569461|uniprotkb:P26437|intact:UNK-5383724|uniprotkb:A2RTC5|ensembl:ENSMUSP00000020717|ensembl:ENSMUSP00000127281 psi-mi:caps2_mouse(display_long)|uniprotkb:Caps2(gene name synonym)|uniprotkb:Cadps2(gene name)|psi-mi:Cadps2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym) psi-mi:arf5_mouse(display_long)|uniprotkb:Arf5(gene name)|psi-mi:Arf5(display_short) psi-mi:"MI:0096"(pull down) Sadakata et al. (2012) pubmed:22111578|mint:MINT-8292254|doi:10.1111/j.1742-4658.2011.08431 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7569786|mint:MINT-8293675 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR033227|refseq:NP_001239034.1|interpro:IPR014770(Munc13 homology 1)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990504"(dense core granule exocytosis)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|refseq:XP_006505175.1|mint:MINT-8293678(identity) refseq:NP_031506.1|ensembl:ENSMUSG00000020440(gene)|ensembl:ENSMUST00000020717(transcript)|ensembl:ENSMUST00000169841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-MMU-6807878|reactome:R-MMU-6811434|mint:MINT-8293677(identity) - comment:mint function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint|comment:homomint figure legend:f4b|comment:domino|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/11/15 2014/10/16 rogid:+1lQkMKobdSe0zpfqCQACMpj73w10090 rogid:da8exbGR3MGxZ6CPZqLvqJbyUYI10090 intact-crc:3B00BC058C392A5B|rigid:kB7bI1WjlhP3ZkjniSvfpciU5Es false glutathione s tranferase tag:?-?(MINT-8293680)|binding-associated region:491-594(IPR001849;) maltose binding protein tag:?-?(MINT-8293686) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot)