#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q06163 uniprotkb:Q12464 intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W intact:EBI-31814|uniprotkb:D6W3D5|ensemblfungi:YPL235W psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name) psi-mi:ruvb2_yeast(display_long)|uniprotkb:TIP49-homology protein 2(gene name synonym)|uniprotkb:TIP49b homolog(gene name synonym)|uniprotkb:RVB2(gene name)|psi-mi:RVB2(display_short)|uniprotkb:TIH2(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:YPL235W(locus name)|uniprotkb:P1060(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Grandin et al. (2011) pubmed:22100294|imex:IM-16736|mint:MINT-8289395|doi:10.1016/j.febslet.2011.11.013 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7564024|mint:MINT-8289408|imex:IM-16736-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891|mint:MINT-8289411(identity) refseq:NP_015089.1|sgd:S000006156|dip:DIP-5207N|mint:Q12464|ensemblfungi:YPL235W(gene)|ensemblfungi:YPL235W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|rcsb pdb:5OUN|rcsb pdb:6GEJ|rcsb pdb:6GEN|mint:MINT-8289410(identity) - crc64:84540735E3CD40F5 crc64:0D8EFBA7EC711AB8 comment:homomint|comment:domino|comment:mint|figure legend:f1a f1b f1c f1d f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/11/09 2014/10/16 rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292 rogid:+msMK6AgZ+aJt0cpuIV7g6JtWr4559292 intact-crc:1E289AE0A2C1B4B0|rigid:E62YFhxqaIeDHryHKe2lVtLh8x0 false myc tag:?-?(MINT-8289424)|binding-associated region:420-740(MINT-8289427) ha tag:?-?(MINT-8289420) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32797 uniprotkb:Q12464 intact:EBI-4187|uniprotkb:Q07650|uniprotkb:D6VRD4|ensemblfungi:YDL220C intact:EBI-31814|uniprotkb:D6W3D5|ensemblfungi:YPL235W psi-mi:cdc13_yeast(display_long)|uniprotkb:CDC13(gene name)|psi-mi:CDC13(display_short)|uniprotkb:YDL220C(locus name) psi-mi:ruvb2_yeast(display_long)|uniprotkb:TIP49-homology protein 2(gene name synonym)|uniprotkb:TIP49b homolog(gene name synonym)|uniprotkb:RVB2(gene name)|psi-mi:RVB2(display_short)|uniprotkb:TIH2(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:YPL235W(locus name)|uniprotkb:P1060(orf name) psi-mi:"MI:0030"(cross-linking study) Grandin et al. (2011) pubmed:22100294|imex:IM-16736|mint:MINT-8289395|doi:10.1016/j.febslet.2011.11.013 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7564077|mint:MINT-8289434|imex:IM-16736-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010061.1|sgd:S000002379|dip:DIP-1229N|mint:P32797|ensemblfungi:YDL220C(gene)|ensemblfungi:YDL220C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007049"(cell cycle)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0016233"(telomere capping)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061770"(translation elongation factor binding)|go:"GO:0071166"(ribonucleoprotein complex localization)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1990879"(CST complex)|interpro:IPR011564(Telomere end binding protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028389|interpro:IPR031749|interpro:IPR040650|interpro:IPR041028|rcsb pdb:1KXL|rcsb pdb:1S40|rcsb pdb:3NWS|rcsb pdb:3NWT|rcsb pdb:3OIP|rcsb pdb:3OIQ|rcsb pdb:4HCE|mint:MINT-8289440(identity) refseq:NP_015089.1|sgd:S000006156|dip:DIP-5207N|mint:Q12464|ensemblfungi:YPL235W(gene)|ensemblfungi:YPL235W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|rcsb pdb:5OUN|rcsb pdb:6GEJ|rcsb pdb:6GEN|mint:MINT-8289436(identity) - crc64:9FE0AD08520A6F8A crc64:0D8EFBA7EC711AB8 figure legend:f2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/11/09 2014/10/16 rogid:gEY0/HOYDHm74lrl6CSs1ZGNpkA559292 rogid:+msMK6AgZ+aJt0cpuIV7g6JtWr4559292 intact-crc:F5AF4842342D296F|rigid:60enaEfrhIY0u3YW87K5lb9J5Zk false myc tag:?-?(MINT-8289444) ha tag:?-?(MINT-8289437) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)