#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P24869	uniprotkb:Q03898	intact:EBI-4515|uniprotkb:D6W4B8|ensemblfungi:YPR119W	intact:EBI-32941|uniprotkb:D6VSB6|ensemblfungi:YDR130C	psi-mi:cg22_yeast(display_long)|uniprotkb:CLB2(gene name)|psi-mi:CLB2(display_short)|uniprotkb:P9642.6(orf name)|uniprotkb:YPR119W(locus name)	psi-mi:fin1_yeast(display_long)|uniprotkb:FIN1(gene name)|psi-mi:FIN1(display_short)|uniprotkb:YDR130C(locus name)|uniprotkb:YD9302.05C(orf name)|uniprotkb:Filaments in between nuclei protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279094|imex:IM-16630-2	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015444.1|sgd:S000006323|mint:P24869|dip:DIP-658N|ensemblfungi:YPR119W(gene)|ensemblfungi:YPR119W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_010415.1|sgd:S000002537|mint:Q03898|dip:DIP-1342N|ensemblfungi:YDR130C(gene)|ensemblfungi:YDR130C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR035260	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	crc64:B68FF888871022A0	crc64:FD4DB73A50F50172	figure legend:Figs. 4B, 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	km:6.7x10^-6(molar)	2011/12/02	2014/10/16	rogid:9pN1AHtkN1tX8cBgI7zsFYNJFQc559292	rogid:UIP0DXEBnmyRNBjq49KcEQeDjEY559292	intact-crc:B685E0D7CFD652AA|rigid:7MbkhEvjbWHaXBVouscDj85cQE8	false	-	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P24869	uniprotkb:P38826	intact:EBI-4515|uniprotkb:D6W4B8|ensemblfungi:YPR119W	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	psi-mi:cg22_yeast(display_long)|uniprotkb:CLB2(gene name)|psi-mi:CLB2(display_short)|uniprotkb:P9642.6(orf name)|uniprotkb:YPR119W(locus name)	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279112|imex:IM-16630-1	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015444.1|sgd:S000006323|mint:P24869|dip:DIP-658N|ensemblfungi:YPR119W(gene)|ensemblfungi:YPR119W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	crc64:B68FF888871022A0	crc64:22803C70378B7E85	figure legend:Figs. 4B, 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	km:2.95x10^-6(molar)	2011/12/02	2014/10/16	rogid:9pN1AHtkN1tX8cBgI7zsFYNJFQc559292	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	intact-crc:69C8EF1EBF0023D0|rigid:uZ26m+gYozYJbADRcxK5LRLVaU4	false	his tag:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P38283	uniprotkb:P24869	intact:EBI-20842|uniprotkb:D6VQF1|ensemblfungi:YBR156C	intact:EBI-4515|uniprotkb:D6W4B8|ensemblfungi:YPR119W	psi-mi:sli15_yeast(display_long)|uniprotkb:YBR1206(orf name)|uniprotkb:YBR156C(locus name)|uniprotkb:SLI15(gene name)|psi-mi:SLI15(display_short)	psi-mi:cg22_yeast(display_long)|uniprotkb:CLB2(gene name)|psi-mi:CLB2(display_short)|uniprotkb:P9642.6(orf name)|uniprotkb:YPR119W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279106|imex:IM-16630-4	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009714.3|sgd:S000000360|mint:P38283|dip:DIP-5807N|ensemblfungi:YBR156C(gene)|ensemblfungi:YBR156C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051233"(spindle midzone)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005635(Inner centromere protein, ARK binding region)	refseq:NP_015444.1|sgd:S000006323|mint:P24869|dip:DIP-658N|ensemblfungi:YPR119W(gene)|ensemblfungi:YPR119W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	crc64:827AC2AB884BA7D1	crc64:B68FF888871022A0	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	km:1.11x10^-6(molar)	2011/12/02	2014/10/16	rogid:fMYGL1RvH57xiA7RKhOarHL9DIg559292	rogid:9pN1AHtkN1tX8cBgI7zsFYNJFQc559292	intact-crc:0281E2ECE490B817|rigid:Nh70qpJwutdUiNip7bTPnFzQcAQ	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P24869	uniprotkb:P35734	intact:EBI-4515|uniprotkb:D6W4B8|ensemblfungi:YPR119W	intact:EBI-26682|uniprotkb:Q68EC3|uniprotkb:Q6B290|uniprotkb:D6VXN5|ensemblfungi:YKL052C	psi-mi:cg22_yeast(display_long)|uniprotkb:CLB2(gene name)|psi-mi:CLB2(display_short)|uniprotkb:P9642.6(orf name)|uniprotkb:YPR119W(locus name)	psi-mi:ask1_yeast(display_long)|uniprotkb:YKL052C(locus name)|uniprotkb:YKL306(orf name)|uniprotkb:ASK1(gene name)|psi-mi:ASK1(display_short)|uniprotkb:Outer kinetochore protein ASK1(gene name synonym)|uniprotkb:Associated with spindles and kinetochores protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279100|imex:IM-16630-3	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015444.1|sgd:S000006323|mint:P24869|dip:DIP-658N|ensemblfungi:YPR119W(gene)|ensemblfungi:YPR119W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_012872.2|sgd:S000001535|mint:P35734|dip:DIP-1928N|go:"GO:0031116"(positive regulation of microtubule polymerization)|ensemblfungi:YKL052C(gene)|ensemblfungi:YKL052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0042729"(DASH complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|interpro:IPR013964(DASH complex, subunit Ask1)	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	crc64:B68FF888871022A0	-	figure legend:Figs. 4B, 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	km:3.48x10^-6(molar)	2011/12/02	2014/10/16	rogid:9pN1AHtkN1tX8cBgI7zsFYNJFQc559292	rogid:yGd7NvJLn1sfJWQVXm6gjh6mX5w559292	intact-crc:77B9C1833D4FD909|rigid:vaR22Or4S3QxuLOxSiX0SXK4eOI	false	-	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q00684	uniprotkb:P38283	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	intact:EBI-20842|uniprotkb:D6VQF1|ensemblfungi:YBR156C	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:sli15_yeast(display_long)|uniprotkb:YBR1206(orf name)|uniprotkb:YBR156C(locus name)|uniprotkb:SLI15(gene name)|psi-mi:SLI15(display_short)	psi-mi:"MI:0096"(pull down)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279279|imex:IM-16630-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	refseq:NP_009714.3|sgd:S000000360|mint:P38283|dip:DIP-5807N|ensemblfungi:YBR156C(gene)|ensemblfungi:YBR156C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051233"(spindle midzone)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005635(Inner centromere protein, ARK binding region)	psi-mi:"MI:0469"(intact)	crc64:4EB3985DFA3FD823	crc64:827AC2AB884BA7D1	figure legend:Supp. Fig. 4|comment:Binding was stronger using phosphorylated substrates, although Cdc14 clearly interacted with Sli1 independently of phosphorylation.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	rogid:fMYGL1RvH57xiA7RKhOarHL9DIg559292	intact-crc:026EE53DD8A0059C|rigid:XAae+/pnnKEPk6NFammQUKv7Z2Y	false	glutathione s tranferase tag:?-?|mutation:283-283	his tag:?-?|phosphorylated residue:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q03898	uniprotkb:Q00684	intact:EBI-32941|uniprotkb:D6VSB6|ensemblfungi:YDR130C	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:fin1_yeast(display_long)|uniprotkb:FIN1(gene name)|psi-mi:FIN1(display_short)|uniprotkb:YDR130C(locus name)|uniprotkb:YD9302.05C(orf name)|uniprotkb:Filaments in between nuclei protein 1(gene name synonym)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0096"(pull down)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279291|imex:IM-16630-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010415.1|sgd:S000002537|mint:Q03898|dip:DIP-1342N|ensemblfungi:YDR130C(gene)|ensemblfungi:YDR130C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR035260	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	psi-mi:"MI:0469"(intact)	crc64:FD4DB73A50F50172	crc64:4EB3985DFA3FD823	figure legend:Supp. Fig. 4B|comment:Binding was stronger using phosphorylated substrates, although Cdc14 clearly interacted with Fin1 independently of phosphorylation.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:UIP0DXEBnmyRNBjq49KcEQeDjEY559292	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:6E0DDF576A5887B4|rigid:Bh0U8t4mR1cymh4BuQsr7GaY8Lk	false	his tag:?-?|phosphorylated residue:?-?	mutation:283-283|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P35734	uniprotkb:Q00684	intact:EBI-26682|uniprotkb:Q68EC3|uniprotkb:Q6B290|uniprotkb:D6VXN5|ensemblfungi:YKL052C	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:ask1_yeast(display_long)|uniprotkb:YKL052C(locus name)|uniprotkb:YKL306(orf name)|uniprotkb:ASK1(gene name)|psi-mi:ASK1(display_short)|uniprotkb:Outer kinetochore protein ASK1(gene name synonym)|uniprotkb:Associated with spindles and kinetochores protein 1(gene name synonym)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0096"(pull down)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279287|imex:IM-16630-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012872.2|sgd:S000001535|mint:P35734|dip:DIP-1928N|go:"GO:0031116"(positive regulation of microtubule polymerization)|ensemblfungi:YKL052C(gene)|ensemblfungi:YKL052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0042729"(DASH complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|interpro:IPR013964(DASH complex, subunit Ask1)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	psi-mi:"MI:0469"(intact)	-	crc64:4EB3985DFA3FD823	figure legend:Supp. Fig. 4B|comment:Binding was stronger using phosphorylated substrates, although Cdc14 clearly interacted with Ask1 independently of phosphorylation.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:yGd7NvJLn1sfJWQVXm6gjh6mX5w559292	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:BF84BA15055230BB|rigid:dS2aopixKTOrhlX9vQwzytOSgRY	false	phosphorylated residue:?-?|his tag:?-?	mutation:283-283|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q00684	uniprotkb:P38826	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279283|imex:IM-16630-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	psi-mi:"MI:0469"(intact)	crc64:4EB3985DFA3FD823	crc64:22803C70378B7E85	figure legend:Supp. Fig. 4B|comment:Binding was stronger using phosphorylated substrates, although Cdc14 clearly interacted with Orc6 independently of phosphorylation.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	intact-crc:F61D5AC4F8715323|rigid:PPUL6eDrtmqYsGJ/7pE9QMVS9Fg	false	glutathione s tranferase tag:?-?|mutation:283-283	his tag:?-?|phosphorylated residue:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q03898	uniprotkb:P24869	intact:EBI-32941|uniprotkb:D6VSB6|ensemblfungi:YDR130C	intact:EBI-4515|uniprotkb:D6W4B8|ensemblfungi:YPR119W	psi-mi:fin1_yeast(display_long)|uniprotkb:FIN1(gene name)|psi-mi:FIN1(display_short)|uniprotkb:YDR130C(locus name)|uniprotkb:YD9302.05C(orf name)|uniprotkb:Filaments in between nuclei protein 1(gene name synonym)	psi-mi:cg22_yeast(display_long)|uniprotkb:CLB2(gene name)|psi-mi:CLB2(display_short)|uniprotkb:P9642.6(orf name)|uniprotkb:YPR119W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279129|imex:IM-16630-14	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010415.1|sgd:S000002537|mint:Q03898|dip:DIP-1342N|ensemblfungi:YDR130C(gene)|ensemblfungi:YDR130C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR035260	refseq:NP_015444.1|sgd:S000006323|mint:P24869|dip:DIP-658N|ensemblfungi:YPR119W(gene)|ensemblfungi:YPR119W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	crc64:FD4DB73A50F50172	crc64:B68FF888871022A0	figure legend:Supp. Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:UIP0DXEBnmyRNBjq49KcEQeDjEY559292	rogid:9pN1AHtkN1tX8cBgI7zsFYNJFQc559292	intact-crc:EADC111AB6D414D9|rigid:7MbkhEvjbWHaXBVouscDj85cQE8	false	his tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P38283	uniprotkb:P24869	intact:EBI-20842|uniprotkb:D6VQF1|ensemblfungi:YBR156C	intact:EBI-4515|uniprotkb:D6W4B8|ensemblfungi:YPR119W	psi-mi:sli15_yeast(display_long)|uniprotkb:YBR1206(orf name)|uniprotkb:YBR156C(locus name)|uniprotkb:SLI15(gene name)|psi-mi:SLI15(display_short)	psi-mi:cg22_yeast(display_long)|uniprotkb:CLB2(gene name)|psi-mi:CLB2(display_short)|uniprotkb:P9642.6(orf name)|uniprotkb:YPR119W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279137|imex:IM-16630-13	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009714.3|sgd:S000000360|mint:P38283|dip:DIP-5807N|ensemblfungi:YBR156C(gene)|ensemblfungi:YBR156C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051233"(spindle midzone)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005635(Inner centromere protein, ARK binding region)	refseq:NP_015444.1|sgd:S000006323|mint:P24869|dip:DIP-658N|ensemblfungi:YPR119W(gene)|ensemblfungi:YPR119W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	crc64:827AC2AB884BA7D1	crc64:B68FF888871022A0	figure legend:Supp. Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:fMYGL1RvH57xiA7RKhOarHL9DIg559292	rogid:9pN1AHtkN1tX8cBgI7zsFYNJFQc559292	intact-crc:E0FC349FE8A19ADC|rigid:Nh70qpJwutdUiNip7bTPnFzQcAQ	false	his tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P24869	uniprotkb:P38826	intact:EBI-4515|uniprotkb:D6W4B8|ensemblfungi:YPR119W	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	psi-mi:cg22_yeast(display_long)|uniprotkb:CLB2(gene name)|psi-mi:CLB2(display_short)|uniprotkb:P9642.6(orf name)|uniprotkb:YPR119W(locus name)	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279133|imex:IM-16630-16	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015444.1|sgd:S000006323|mint:P24869|dip:DIP-658N|ensemblfungi:YPR119W(gene)|ensemblfungi:YPR119W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	crc64:B68FF888871022A0	crc64:22803C70378B7E85	figure legend:Supp. Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:9pN1AHtkN1tX8cBgI7zsFYNJFQc559292	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	intact-crc:679067AF1DC61638|rigid:uZ26m+gYozYJbADRcxK5LRLVaU4	false	-	his tag:?-?	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P24869	uniprotkb:P35734	intact:EBI-4515|uniprotkb:D6W4B8|ensemblfungi:YPR119W	intact:EBI-26682|uniprotkb:Q68EC3|uniprotkb:Q6B290|uniprotkb:D6VXN5|ensemblfungi:YKL052C	psi-mi:cg22_yeast(display_long)|uniprotkb:CLB2(gene name)|psi-mi:CLB2(display_short)|uniprotkb:P9642.6(orf name)|uniprotkb:YPR119W(locus name)	psi-mi:ask1_yeast(display_long)|uniprotkb:YKL052C(locus name)|uniprotkb:YKL306(orf name)|uniprotkb:ASK1(gene name)|psi-mi:ASK1(display_short)|uniprotkb:Outer kinetochore protein ASK1(gene name synonym)|uniprotkb:Associated with spindles and kinetochores protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279125|imex:IM-16630-15	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015444.1|sgd:S000006323|mint:P24869|dip:DIP-658N|ensemblfungi:YPR119W(gene)|ensemblfungi:YPR119W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_012872.2|sgd:S000001535|mint:P35734|dip:DIP-1928N|go:"GO:0031116"(positive regulation of microtubule polymerization)|ensemblfungi:YKL052C(gene)|ensemblfungi:YKL052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0042729"(DASH complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|interpro:IPR013964(DASH complex, subunit Ask1)	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	crc64:B68FF888871022A0	-	figure legend:Supp. Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:9pN1AHtkN1tX8cBgI7zsFYNJFQc559292	rogid:yGd7NvJLn1sfJWQVXm6gjh6mX5w559292	intact-crc:3D6000269780E640|rigid:vaR22Or4S3QxuLOxSiX0SXK4eOI	false	-	his tag:?-?	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00684	uniprotkb:P38283	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	intact:EBI-20842|uniprotkb:D6VQF1|ensemblfungi:YBR156C	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:sli15_yeast(display_long)|uniprotkb:YBR1206(orf name)|uniprotkb:YBR156C(locus name)|uniprotkb:SLI15(gene name)|psi-mi:SLI15(display_short)	psi-mi:"MI:0434"(phosphatase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279198|imex:IM-16630-10	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	refseq:NP_009714.3|sgd:S000000360|mint:P38283|dip:DIP-5807N|ensemblfungi:YBR156C(gene)|ensemblfungi:YBR156C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051233"(spindle midzone)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005635(Inner centromere protein, ARK binding region)	go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)	crc64:4EB3985DFA3FD823	crc64:827AC2AB884BA7D1	figure legend:Fig. 6, 7A, 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	rogid:fMYGL1RvH57xiA7RKhOarHL9DIg559292	intact-crc:233D791D8B714932|rigid:XAae+/pnnKEPk6NFammQUKv7Z2Y	false	his tag:?-?	his tag:?-?|phosphorylated residue:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P35734	uniprotkb:Q00684	intact:EBI-26682|uniprotkb:Q68EC3|uniprotkb:Q6B290|uniprotkb:D6VXN5|ensemblfungi:YKL052C	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:ask1_yeast(display_long)|uniprotkb:YKL052C(locus name)|uniprotkb:YKL306(orf name)|uniprotkb:ASK1(gene name)|psi-mi:ASK1(display_short)|uniprotkb:Outer kinetochore protein ASK1(gene name synonym)|uniprotkb:Associated with spindles and kinetochores protein 1(gene name synonym)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0434"(phosphatase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279202|imex:IM-16630-9	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012872.2|sgd:S000001535|mint:P35734|dip:DIP-1928N|go:"GO:0031116"(positive regulation of microtubule polymerization)|ensemblfungi:YKL052C(gene)|ensemblfungi:YKL052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0042729"(DASH complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|interpro:IPR013964(DASH complex, subunit Ask1)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	go:"GO:0006470"(protein dephosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)	-	crc64:4EB3985DFA3FD823	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:yGd7NvJLn1sfJWQVXm6gjh6mX5w559292	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:8934EF8768B51E7B|rigid:dS2aopixKTOrhlX9vQwzytOSgRY	false	his tag:?-?|phosphorylated residue:?-?	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q00684	uniprotkb:P38826	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:"MI:0434"(phosphatase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279190|imex:IM-16630-12	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	go:"GO:0006470"(protein dephosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)	crc64:4EB3985DFA3FD823	crc64:22803C70378B7E85	figure legend:Fig. 6, &A, 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	intact-crc:801C7EF7F4B1EBB7|rigid:PPUL6eDrtmqYsGJ/7pE9QMVS9Fg	false	his tag:?-?	his tag:?-?|phosphorylated residue:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q00684	uniprotkb:Q03898	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	intact:EBI-32941|uniprotkb:D6VSB6|ensemblfungi:YDR130C	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:fin1_yeast(display_long)|uniprotkb:FIN1(gene name)|psi-mi:FIN1(display_short)|uniprotkb:YDR130C(locus name)|uniprotkb:YD9302.05C(orf name)|uniprotkb:Filaments in between nuclei protein 1(gene name synonym)	psi-mi:"MI:0434"(phosphatase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279194|imex:IM-16630-11	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	refseq:NP_010415.1|sgd:S000002537|mint:Q03898|dip:DIP-1342N|ensemblfungi:YDR130C(gene)|ensemblfungi:YDR130C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR035260	go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)	crc64:4EB3985DFA3FD823	crc64:FD4DB73A50F50172	figure legend:Fig. 6, 7A, 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	rogid:UIP0DXEBnmyRNBjq49KcEQeDjEY559292	intact-crc:6295D08A66BA7EB0|rigid:Bh0U8t4mR1cymh4BuQsr7GaY8Lk	false	his tag:?-?	his tag:?-?|phosphorylated residue:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
chebi:"CHEBI:61146"	uniprotkb:Q00684	intact:EBI-5279244	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:"4-nitrophenyl phosphate(2−)"(display_short)|psi-mi:"CHEBI:61146"(display_long)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0434"(phosphatase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279253|imex:IM-16630-17	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	go:"GO:0016791"(phosphatase activity)	-	crc64:4EB3985DFA3FD823	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	-	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:E5E68F9C24404E1C	false	-	mutation:283-283|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
chebi:"CHEBI:61146"	uniprotkb:Q00684	intact:EBI-5279244	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:"4-nitrophenyl phosphate(2−)"(display_short)|psi-mi:"CHEBI:61146"(display_long)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0434"(phosphatase assay)	Bouchoux et al. (2011)	pubmed:22078879|imex:IM-16630	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5279262|imex:IM-16630-18	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	go:"GO:0016791"(phosphatase activity)	-	crc64:4EB3985DFA3FD823	figure legend:Supp. Fig. 4A|comment:CDC14 Cys293His mutation was catalytically inactive|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2014/10/16	-	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:E5DAD0CCBA71B9C9	false	-	his tag:?-?|mutation:283-283	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)