#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43463	uniprotkb:O00257	intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym)	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:"MI:0515"(methyltransferase assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277008|imex:IM-16600-1	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0006479"(protein methylation)	-	-	figure legend:Fig. 1A, B, D|comment:"A Suv39h1 hyperactive mutant (H320R) further enhanced the methylation of CBX4, whereas an enzymatically inactive Suv39h1 mutant (H324L)   failed to use Pc2 as substrate. A Lys191Arg mutation of CBX4 prevented phosphorylation of CBX4."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/29	2014/10/16	rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	intact-crc:5971F035752DDFC3|rigid:V8kFJc/3ot463uK1EgQCwa+b9S0	false	glutathione s tranferase tag:?-?|mutation:320-320|mutation:324-324	his tag:?-?|mutation:191-191	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:O00257	uniprotkb:Q9H3R0	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:"MI:0870"(demethylase assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0871"(demethylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277045|imex:IM-16600-4	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	go:"GO:0032451"(demethylase activity)|go:"GO:0006482"(protein demethylation)	-	-	figure legend:Fig. 2A, 2B|comment:The enzymatically inactive KDM4C-His190Gly/Glu192Aala mutant  failed to demethylate CBX4 Lys191me2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	intact-crc:BE96138F4B9749DF|rigid:Z72LW1PY1k1Ort8Pp7feM4vub0I	false	methylated lysine:191-191|his tag:?-?	mutation:190-190,192-192|flag tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:O00257	uniprotkb:P31946	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277169|imex:IM-16600-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	intact-crc:A17AEEFE12FCD378|rigid:aSLoxicIJl+2JwgFEHE9RfainTI	false	N6-methyl-L-lysine:191-191	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00257	uniprotkb:P31946	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277175|imex:IM-16600-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	intact-crc:EE3FD137C6410F8D|rigid:fjZLVvVJ0M3YMCZ46oyq9LH2+JU	false	N6,N6-dimethyl-L-lysine:191-191	N6-methyl-L-lysine:191-191	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00257	uniprotkb:P35226	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277175|imex:IM-16600-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606	intact-crc:EE3FD137C6410F8D|rigid:fjZLVvVJ0M3YMCZ46oyq9LH2+JU	false	N6,N6-dimethyl-L-lysine:191-191	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00257	uniprotkb:P78364	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277175|imex:IM-16600-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606	intact-crc:EE3FD137C6410F8D|rigid:fjZLVvVJ0M3YMCZ46oyq9LH2+JU	false	N6,N6-dimethyl-L-lysine:191-191	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00257	uniprotkb:Q06587	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277175|imex:IM-16600-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606	intact-crc:EE3FD137C6410F8D|rigid:fjZLVvVJ0M3YMCZ46oyq9LH2+JU	false	N6,N6-dimethyl-L-lysine:191-191	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
ensembl:ENSG00000094804	uniprotkb:Q9H3R0	intact:EBI-5277733	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	psi-mi:cdc6_human_gene(display_short)|psi-mi:ENSG00000094804(display_long)	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278019|imex:IM-16600-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	figure legend:Fig. 2D|agonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	intact-crc:256AB9418398D78F	false	binding-associated region:?-?	flag tag:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000105996	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277728	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:hxa2_human_gene(display_short)|psi-mi:ENSG00000105996(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277771|imex:IM-16600-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:D2A49F54EACFA1C4	false	N6,N6-dimethyl-L-lysine:191-191	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q9H3R0	ensembl:ENSG00000105173	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	intact:EBI-1265562	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:ccne1_human_gene(display_short)|psi-mi:ENSG00000105173(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278002|imex:IM-16600-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	-	figure legend:Fig. 2E, F|agonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	-	intact-crc:3CCDD863D2D8ACE1	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000228716	uniprotkb:Q96GN5	intact:EBI-5277737	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	psi-mi:dyr_human_gene(display_short)|psi-mi:ENSG00000228716(display_long)	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278824|imex:IM-16600-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	intact-crc:6786D0CEFC649471	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q96GN5	ensembl:ENSG00000112118	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	intact:EBI-5277739	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:mcm3_human_gene(display_short)|psi-mi:ENSG00000112118(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278833|imex:IM-16600-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	-	figure legend:Fig. 7C|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	-	intact-crc:C64D42966002F4EB	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000112118	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277739	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:mcm3_human_gene(display_short)|psi-mi:ENSG00000112118(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277923|imex:IM-16600-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|agonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:DCC3AF2F1B0239DF	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q9H3R0	ensembl:ENSG00000080839	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	intact:EBI-5277760	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:rbl1_human_gene(display_short)|psi-mi:ENSG00000080839(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277962|imex:IM-16600-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	-	figure legend:Fig. 2E, F|antagonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	-	intact-crc:43713F629A137C0D	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000228716	uniprotkb:Q9H3R0	intact:EBI-5277737	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	psi-mi:dyr_human_gene(display_short)|psi-mi:ENSG00000228716(display_long)	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278036|imex:IM-16600-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	figure legend:Fig. 2E, F|agonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	intact-crc:9DA897A2F0B1F832	false	binding-associated region:?-?	flag tag:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000101868	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277747	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:dpola_human_gene(display_short)|psi-mi:ENSG00000101868(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277955|imex:IM-16600-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|agonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:6D369395658B3080	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000134057	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277735	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:ccnb1_human_gene(display_short)|psi-mi:ENSG00000134057(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277908|imex:IM-16600-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|agonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:CCE71C24D092C653	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q96GN5	ensembl:ENSG00000080839	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	intact:EBI-5277760	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:rbl1_human_gene(display_short)|psi-mi:ENSG00000080839(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278921|imex:IM-16600-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	-	figure legend:Fig. 7C|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	-	intact-crc:5E46788A810BEAE9	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q96GN5	ensembl:ENSG00000101868	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	intact:EBI-5277747	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:dpola_human_gene(display_short)|psi-mi:ENSG00000101868(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278896|imex:IM-16600-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	-	figure legend:Fig. 7C|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	-	intact-crc:77B87E2C1E8BFDB4	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q96GN5	ensembl:ENSG00000132646	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	intact:EBI-5277745	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:pcna_human_gene(display_short)|psi-mi:ENSG00000132646(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278885|imex:IM-16600-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	-	figure legend:Fig. 7C|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	-	intact-crc:D9E82627BB78CDA6	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q96GN5	ensembl:ENSG00000132646	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	intact:EBI-5277745	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:pcna_human_gene(display_short)|psi-mi:ENSG00000132646(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278870|imex:IM-16600-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	-	figure legend:Fig. 7C|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	-	intact-crc:D9E82627BB78CDA6	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q96GN5	ensembl:ENSG00000134057	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	intact:EBI-5277735	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:ccnb1_human_gene(display_short)|psi-mi:ENSG00000134057(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278813|imex:IM-16600-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	-	figure legend:Fig. 7C|agonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	-	intact-crc:7969F19DAB920B65	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000094804	uniprotkb:Q96GN5	intact:EBI-5277733	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	psi-mi:cdc6_human_gene(display_short)|psi-mi:ENSG00000094804(display_long)	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278802|imex:IM-16600-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	figure legend:Fig. 7C|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	intact-crc:31802D3BFAD366D1	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q96GN5	ensembl:ENSG00000105173	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	intact:EBI-1265562	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:ccne1_human_gene(display_short)|psi-mi:ENSG00000105173(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278793|imex:IM-16600-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	-	figure legend:Fig. 7C|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	-	intact-crc:1F4592E6D3DF503F	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000228716	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277737	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:dyr_human_gene(display_short)|psi-mi:ENSG00000228716(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277915|imex:IM-16600-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|agonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:DBEE8D7787645943	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q96GN5	ensembl:ENSG00000085840	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	intact:EBI-5277743	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:orc1_human_gene(display_short)|psi-mi:ENSG00000085840(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278859|imex:IM-16600-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	-	figure legend:Fig. 7C|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	-	intact-crc:2960B42F6ED4BFD5	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000164045	uniprotkb:O00257	intact:EBI-5277731	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	psi-mi:mpip1_human_gene(display_short)|psi-mi:ENSG00000164045(display_long)	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277893|imex:IM-16600-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	figure legend:Fig. 2D|agonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	intact-crc:0C195A65DBC9CEAC	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000132646	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277745	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:pcna_human_gene(display_short)|psi-mi:ENSG00000132646(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277851|imex:IM-16600-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:0A55944032C3A0C5	false	N6,N6-dimethyl-L-lysine:191-191	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000228716	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277737	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:dyr_human_gene(display_short)|psi-mi:ENSG00000228716(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277815|imex:IM-16600-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:E9007D6E6AC39B5B	false	N6,N6-dimethyl-L-lysine:191-191	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000134057	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277735	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:ccnb1_human_gene(display_short)|psi-mi:ENSG00000134057(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277806|imex:IM-16600-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:F61C8FABC94FF1D0	false	N6,N6-dimethyl-L-lysine:191-191	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000095002	uniprotkb:Q96GN5	intact:EBI-5277741	intact:EBI-5278764|uniprotkb:A4D141|uniprotkb:A6NF50|uniprotkb:Q6PIL4|uniprotkb:Q86YT0|uniprotkb:Q8IXN5|uniprotkb:Q96C70|uniprotkb:Q9H9A2|uniprotkb:Q9NPV2|uniprotkb:B3KTR5|uniprotkb:B4DUT3|uniprotkb:C9K0Y1|intact:EBI-10968052|ensembl:ENSP00000383986	psi-mi:msh2_human_gene(display_short)|psi-mi:ENSG00000095002(display_long)	psi-mi:cda7l_human(display_long)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278850|imex:IM-16600-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001120842.1|refseq:NP_001120843.1|refseq:NP_061189.2|dip:DIP-61218N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018866|ensembl:ENSG00000164649(gene)|ensembl:ENST00000406877(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|interpro:IPR033578|interpro:IPR040221|mint:Q96GN5|rcsb pdb:5YI9|rcsb pdb:6EMO	-	-	-	figure legend:Fig. 7C|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:M/W5AlZrKjprYMUT3f8BDfdZXrY9606	intact-crc:2D02BE01FB5DDA8F	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000080839	uniprotkb:Q9H3R0	intact:EBI-5277760	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	psi-mi:rbl1_human_gene(display_short)|psi-mi:ENSG00000080839(display_long)	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277971|imex:IM-16600-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	figure legend:Fig. 2D|agonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	intact-crc:07B8554C1CBE9AFA	false	binding-associated region:?-?	flag tag:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q9H3R0	ensembl:ENSG00000101868	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	intact:EBI-5277747	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:dpola_human_gene(display_short)|psi-mi:ENSG00000101868(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278078|imex:IM-16600-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	-	figure legend:Fig. 2E, F|agonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	-	intact-crc:D8C003F5174DA078	false	flag tag:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000085840	uniprotkb:Q9H3R0	intact:EBI-5277743	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	psi-mi:orc1_human_gene(display_short)|psi-mi:ENSG00000085840(display_long)	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278062|imex:IM-16600-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	figure legend:Fig. 2E, F|antagonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	intact-crc:B2C611306E3B8C46	false	binding-associated region:?-?	flag tag:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q9H3R0	ensembl:ENSG00000095002	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	intact:EBI-5277741	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:msh2_human_gene(display_short)|psi-mi:ENSG00000095002(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278053|imex:IM-16600-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	-	figure legend:Fig. 2E, F|antagonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	-	intact-crc:2258537A7F2C3615	false	flag tag:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000112118	uniprotkb:Q9H3R0	intact:EBI-5277739	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	psi-mi:mcm3_human_gene(display_short)|psi-mi:ENSG00000112118(display_long)	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278044|imex:IM-16600-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	figure legend:Fig. 2E, F|agonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	intact-crc:7725700E9241A447	false	binding-associated region:?-?	flag tag:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000134057	uniprotkb:Q9H3R0	intact:EBI-5277735	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	psi-mi:ccnb1_human_gene(display_short)|psi-mi:ENSG00000134057(display_long)	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278027|imex:IM-16600-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	figure legend:Fig. 2E, F|agonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	intact-crc:D5FAAF400B95C567	false	binding-associated region:?-?	flag tag:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q9H3R0	ensembl:ENSG00000132646	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	intact:EBI-5277745	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:pcna_human_gene(display_short)|psi-mi:ENSG00000132646(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278070|imex:IM-16600-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	-	figure legend:Fig. 2E, F|antagonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	-	intact-crc:C5E19D826A49D8B0	false	flag tag:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q9H3R0	ensembl:ENSG00000105173	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	intact:EBI-1265562	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:ccne1_human_gene(display_short)|psi-mi:ENSG00000105173(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277994|imex:IM-16600-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	-	figure legend:Fig. 2E, F|agonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	-	intact-crc:3CCDD863D2D8ACE1	false	flag tag:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000132646	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277745	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:pcna_human_gene(display_short)|psi-mi:ENSG00000132646(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277945|imex:IM-16600-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:6C66CB9EC0780090	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000085840	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277743	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:orc1_human_gene(display_short)|psi-mi:ENSG00000085840(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277938|imex:IM-16600-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:9CEE599615D472E3	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000105173	uniprotkb:O00257	intact:EBI-1265562	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	psi-mi:ccne1_human_gene(display_short)|psi-mi:ENSG00000105173(display_long)	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277885|imex:IM-16600-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	figure legend:Fig. 2D|agonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	intact-crc:AACB7F5FA8DF9D09	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000095002	uniprotkb:O00257	intact:EBI-5277741	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	psi-mi:msh2_human_gene(display_short)|psi-mi:ENSG00000095002(display_long)	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277931|imex:IM-16600-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	intact-crc:988C53B8805D17B9	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000094804	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277733	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:cdc6_human_gene(display_short)|psi-mi:ENSG00000094804(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277901|imex:IM-16600-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|agonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:2B0EC08281D3ABE5	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000080839	uniprotkb:O00257	intact:EBI-5277760	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	psi-mi:rbl1_human_gene(display_short)|psi-mi:ENSG00000080839(display_long)	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277869|imex:IM-16600-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	intact-crc:DC8A138A5FC6FCEA	false	binding-associated region:?-?	N6,N6-dimethyl-L-lysine:191-191	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000101868	uniprotkb:O00257	intact:EBI-5277747	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	psi-mi:dpola_human_gene(display_short)|psi-mi:ENSG00000101868(display_long)	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277860|imex:IM-16600-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	-	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	intact-crc:B602EECF8B285DDD	false	binding-associated region:?-?	N6,N6-dimethyl-L-lysine:191-191	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000085840	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277743	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:orc1_human_gene(display_short)|psi-mi:ENSG00000085840(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277842|imex:IM-16600-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:3C80D42D1A56A2E6	false	N6,N6-dimethyl-L-lysine:191-191	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000095002	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277741	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:msh2_human_gene(display_short)|psi-mi:ENSG00000095002(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277833|imex:IM-16600-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:B819BAF3FEF2CFEF	false	N6,N6-dimethyl-L-lysine:191-191	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000094804	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277733	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:cdc6_human_gene(display_short)|psi-mi:ENSG00000094804(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277797|imex:IM-16600-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:9E821B001F9211D0	false	N6,N6-dimethyl-L-lysine:191-191	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000164045	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277731	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:mpip1_human_gene(display_short)|psi-mi:ENSG00000164045(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277788|imex:IM-16600-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:818DC6667667ACC0	false	N6,N6-dimethyl-L-lysine:191-191	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000112118	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-5277739	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:mcm3_human_gene(display_short)|psi-mi:ENSG00000112118(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277824|imex:IM-16600-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:812CB87422DC6193	false	N6,N6-dimethyl-L-lysine:191-191	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O00257	ensembl:ENSG00000105173	intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397	intact:EBI-1265562	psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short)	psi-mi:ccne1_human_gene(display_short)|psi-mi:ENSG00000105173(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5277779|imex:IM-16600-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724	-	-	-	-	figure legend:Fig. 2D|antagonist:Serum|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606	-	intact-crc:96119735D5A979FA	false	N6,N6-dimethyl-L-lysine:191-191	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q9H3R0	ensembl:ENSG00000164045	intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710	intact:EBI-5277731	psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)	psi-mi:mpip1_human_gene(display_short)|psi-mi:ENSG00000164045(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Yang et al. (2011)	pubmed:22078878|imex:IM-16600	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5278010|imex:IM-16600-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886	-	-	-	-	figure legend:Fig. 2D|agonist:Serum|comment:Serum stimulation resulted in increased recruitment of   KDM4C on   target gene promoters   which correlated  with a decreased CBX4 Lys-191me2 level .The  KDM4C-His190Gly/Glu192Ala mutant largely inhibited CBX2 Lys-191me2 demethylation, despite being equally recruited on the same set of promoters|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/11/29	2014/10/16	rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606	-	intact-crc:DEF726D83AA94E42	false	flag tag:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)