#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q80ZD7 uniprotkb:P15387 intact:EBI-7511314|intact:MINT-8298625|ensembl:ENSRNOP00000066608 intact:EBI-7511254|intact:MINT-8283237 psi-mi:amgo1_rat(display_long)|uniprotkb:Amigo1(gene name)|psi-mi:Amigo1(display_short)|uniprotkb:AMIGO-1(gene name synonym)|uniprotkb:Ali2(gene name synonym)|uniprotkb:Alivin-2(gene name synonym)|uniprotkb:Amigo(gene name synonym) psi-mi:kcnb1_rat(display_long)|uniprotkb:Kcnb1(gene name)|psi-mi:Kcnb1(display_short)|uniprotkb:Delayed rectifier potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv2.1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Peltola et al. (2011) pubmed:22056818|imex:IM-16692|mint:MINT-8298551|doi:10.1038/embor.2011.204 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7511308|mint:MINT-8298557|imex:IM-16692-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008759613.1|rgd:1303079|refseq:NP_996764.1|refseq:XP_006233202.1|ensembl:ENSRNOG00000045665(gene)|ensembl:ENSRNOT00000074725(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007409"(axonogenesis)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0106030"(neuron projection fasciculation)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1990030"(pericellular basket)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031283|interpro:IPR031284|interpro:IPR032675|interpro:IPR036179|mint:MINT-8302766(identity) interpro:IPR027359|rcsb pdb:2R9R|rcsb pdb:4JTA|interpro:IPR000210(BTB/POZ-like)|interpro:IPR005821(Ion transport)|interpro:IPR004350(Potassium channel, voltage dependent, Kv2.1)|rcsb pdb:4JTD|rcsb pdb:3LNM|rgd:2954|rcsb pdb:4JTC|interpro:IPR011333(BTB/POZ fold)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|refseq:NP_037318.1|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003973(Potassium channel, voltage dependent, Kv2)|interpro:IPR028325|go:"GO:0000149"(SNARE binding)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:2000671"(regulation of motor neuron apoptotic process)|reactome:R-RNO-1296072|reactome:R-RNO-381676|mint:MINT-8298559(identity) - comment:mint comment:mint comment:mint|figure legend:f1c sf1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-hippocampus_neuron)|taxid:10116(Rattus norvegicus) - 2011/12/14 2014/10/16 rogid:efof1KSDG83eOHvkArLF8pmcTGc10116 rogid:XskxHGYDpeOX7fADwIzU0n2gT4810116 intact-crc:AD036A0A32963291|rigid:pzHB8IDto6VwJHcXw0VUOPajbyw false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q03717 uniprotkb:Q80ZD8 intact:EBI-7511364|uniprotkb:Q8K0D1|intact:MINT-8298631|ensembl:ENSMUSP00000057981|ensembl:ENSMUSP00000147093 intact:EBI-7511393|uniprotkb:Q69ZQ0|uniprotkb:Q8R5D4|uniprotkb:Q921U9|intact:MINT-8298633|uniprotkb:A2AE40|ensembl:ENSMUSP00000061244|ensembl:ENSMUSP00000102267 psi-mi:kcnb1_mouse(display_long)|uniprotkb:Kcnb1(gene name)|psi-mi:Kcnb1(display_short)|uniprotkb:mShab(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv2.1(gene name synonym) psi-mi:amgo1_mouse(display_long)|uniprotkb:Amigo1(gene name)|psi-mi:Amigo1(display_short)|uniprotkb:AMIGO-1(gene name synonym)|uniprotkb:Ali2(gene name synonym)|uniprotkb:Alivin-2(gene name synonym)|uniprotkb:Kiaa1163(gene name synonym)|uniprotkb:Amigo(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Peltola et al. (2011) pubmed:22056818|imex:IM-16692|mint:MINT-8298551|doi:10.1038/embor.2011.204 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7511359|mint:MINT-8302786|imex:IM-16692-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032446.2|interpro:IPR004350(Potassium channel, voltage dependent, Kv2.1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-381676|refseq:XP_017171221.1|refseq:XP_017171222.1|ensembl:ENSMUSG00000050556(gene)|ensembl:ENSMUST00000059826(transcript)|ensembl:ENSMUST00000207917(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:2000671"(regulation of motor neuron apoptotic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003973(Potassium channel, voltage dependent, Kv2)|mint:MINT-8302788(identity) refseq:NP_001004293.1|refseq:NP_666249.2|ensembl:ENSMUSG00000050947(gene)|ensembl:ENSMUST00000050909(transcript)|ensembl:ENSMUST00000106656(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007409"(axonogenesis)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0106030"(neuron projection fasciculation)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1990030"(pericellular basket)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031283|interpro:IPR031284|interpro:IPR032675|interpro:IPR036179|rcsb pdb:2XOT|refseq:NP_001274022.1|mint:MINT-8302789(identity) - comment:mint comment:mint figure legend:f2a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2011/12/14 2014/10/16 rogid:bVGBUW1uvAWqGoo7whe/Oa6Wcv010090 rogid:joHgLy+rO442SPPm6IQrQSzFHNw10090 intact-crc:EE1A9359E2155FEA|rigid:LhtmH8UiIxQ0WAPM2Mee5pY9QM0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03717 uniprotkb:Q80ZD8 intact:EBI-7511364|uniprotkb:Q8K0D1|intact:MINT-8298631|ensembl:ENSMUSP00000057981|ensembl:ENSMUSP00000147093 intact:EBI-7511393|uniprotkb:Q69ZQ0|uniprotkb:Q8R5D4|uniprotkb:Q921U9|intact:MINT-8298633|uniprotkb:A2AE40|ensembl:ENSMUSP00000061244|ensembl:ENSMUSP00000102267 psi-mi:kcnb1_mouse(display_long)|uniprotkb:Kcnb1(gene name)|psi-mi:Kcnb1(display_short)|uniprotkb:mShab(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv2.1(gene name synonym) psi-mi:amgo1_mouse(display_long)|uniprotkb:Amigo1(gene name)|psi-mi:Amigo1(display_short)|uniprotkb:AMIGO-1(gene name synonym)|uniprotkb:Ali2(gene name synonym)|uniprotkb:Alivin-2(gene name synonym)|uniprotkb:Kiaa1163(gene name synonym)|uniprotkb:Amigo(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Peltola et al. (2011) pubmed:22056818|imex:IM-16692|mint:MINT-8298551|doi:10.1038/embor.2011.204 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7511435|mint:MINT-8302795|imex:IM-16692-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032446.2|interpro:IPR004350(Potassium channel, voltage dependent, Kv2.1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-381676|refseq:XP_017171221.1|refseq:XP_017171222.1|ensembl:ENSMUSG00000050556(gene)|ensembl:ENSMUST00000059826(transcript)|ensembl:ENSMUST00000207917(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:2000671"(regulation of motor neuron apoptotic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003973(Potassium channel, voltage dependent, Kv2)|mint:MINT-8302797(identity) refseq:NP_001004293.1|refseq:NP_666249.2|ensembl:ENSMUSG00000050947(gene)|ensembl:ENSMUST00000050909(transcript)|ensembl:ENSMUST00000106656(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007409"(axonogenesis)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0106030"(neuron projection fasciculation)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1990030"(pericellular basket)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031283|interpro:IPR031284|interpro:IPR032675|interpro:IPR036179|rcsb pdb:2XOT|refseq:NP_001274022.1|mint:MINT-8302799(identity) - comment:mint comment:mint figure legend:f2b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2011/12/14 2014/10/16 rogid:bVGBUW1uvAWqGoo7whe/Oa6Wcv010090 rogid:joHgLy+rO442SPPm6IQrQSzFHNw10090 intact-crc:98877A7104DF733C|rigid:LhtmH8UiIxQ0WAPM2Mee5pY9QM0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80ZD8 uniprotkb:Q03717 intact:EBI-7511393|uniprotkb:Q69ZQ0|uniprotkb:Q8R5D4|uniprotkb:Q921U9|intact:MINT-8298633|uniprotkb:A2AE40|ensembl:ENSMUSP00000061244|ensembl:ENSMUSP00000102267 intact:EBI-7511364|uniprotkb:Q8K0D1|intact:MINT-8298631|ensembl:ENSMUSP00000057981|ensembl:ENSMUSP00000147093 psi-mi:amgo1_mouse(display_long)|uniprotkb:Amigo1(gene name)|psi-mi:Amigo1(display_short)|uniprotkb:AMIGO-1(gene name synonym)|uniprotkb:Ali2(gene name synonym)|uniprotkb:Alivin-2(gene name synonym)|uniprotkb:Kiaa1163(gene name synonym)|uniprotkb:Amigo(gene name synonym) psi-mi:kcnb1_mouse(display_long)|uniprotkb:Kcnb1(gene name)|psi-mi:Kcnb1(display_short)|uniprotkb:mShab(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv2.1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Peltola et al. (2011) pubmed:22056818|imex:IM-16692|mint:MINT-8298551|doi:10.1038/embor.2011.204 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7511472|mint:MINT-8302810|imex:IM-16692-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001004293.1|refseq:NP_666249.2|ensembl:ENSMUSG00000050947(gene)|ensembl:ENSMUST00000050909(transcript)|ensembl:ENSMUST00000106656(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007409"(axonogenesis)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0106030"(neuron projection fasciculation)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1990030"(pericellular basket)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031283|interpro:IPR031284|interpro:IPR032675|interpro:IPR036179|rcsb pdb:2XOT|refseq:NP_001274022.1|mint:MINT-8302814(identity) refseq:NP_032446.2|interpro:IPR004350(Potassium channel, voltage dependent, Kv2.1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-381676|refseq:XP_017171221.1|refseq:XP_017171222.1|ensembl:ENSMUSG00000050556(gene)|ensembl:ENSMUST00000059826(transcript)|ensembl:ENSMUST00000207917(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:2000671"(regulation of motor neuron apoptotic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003973(Potassium channel, voltage dependent, Kv2)|mint:MINT-8302812(identity) - comment:mint comment:mint comment:mint|figure legend:sf4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/14 2014/10/16 rogid:joHgLy+rO442SPPm6IQrQSzFHNw10090 rogid:bVGBUW1uvAWqGoo7whe/Oa6Wcv010090 intact-crc:F905D04A7DD3B18E|rigid:LhtmH8UiIxQ0WAPM2Mee5pY9QM0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15387 uniprotkb:Q80ZD7 intact:EBI-7511254|intact:MINT-8283237 intact:EBI-7511314|intact:MINT-8298625|ensembl:ENSRNOP00000066608 psi-mi:kcnb1_rat(display_long)|uniprotkb:Kcnb1(gene name)|psi-mi:Kcnb1(display_short)|uniprotkb:Delayed rectifier potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv2.1(gene name synonym) psi-mi:amgo1_rat(display_long)|uniprotkb:Amigo1(gene name)|psi-mi:Amigo1(display_short)|uniprotkb:AMIGO-1(gene name synonym)|uniprotkb:Ali2(gene name synonym)|uniprotkb:Alivin-2(gene name synonym)|uniprotkb:Amigo(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Peltola et al. (2011) pubmed:22056818|imex:IM-16692|mint:MINT-8298551|doi:10.1038/embor.2011.204 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7511523|mint:MINT-8302836|imex:IM-16692-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027359|rcsb pdb:2R9R|rcsb pdb:4JTA|interpro:IPR000210(BTB/POZ-like)|interpro:IPR005821(Ion transport)|interpro:IPR004350(Potassium channel, voltage dependent, Kv2.1)|rcsb pdb:4JTD|rcsb pdb:3LNM|rgd:2954|rcsb pdb:4JTC|interpro:IPR011333(BTB/POZ fold)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|refseq:NP_037318.1|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003973(Potassium channel, voltage dependent, Kv2)|interpro:IPR028325|go:"GO:0000149"(SNARE binding)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:2000671"(regulation of motor neuron apoptotic process)|reactome:R-RNO-1296072|reactome:R-RNO-381676|mint:MINT-8302838(identity) refseq:XP_008759613.1|rgd:1303079|refseq:NP_996764.1|refseq:XP_006233202.1|ensembl:ENSRNOG00000045665(gene)|ensembl:ENSRNOT00000074725(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007409"(axonogenesis)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0106030"(neuron projection fasciculation)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1990030"(pericellular basket)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031283|interpro:IPR031284|interpro:IPR032675|interpro:IPR036179|mint:MINT-8302840(identity) - comment:mint comment:mint comment:mint|figure legend:sf5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-cerebral_cortica)|taxid:10116(Rattus norvegicus) - 2011/12/14 2014/10/16 rogid:XskxHGYDpeOX7fADwIzU0n2gT4810116 rogid:efof1KSDG83eOHvkArLF8pmcTGc10116 intact-crc:A2298D9F8EE6678A|rigid:pzHB8IDto6VwJHcXw0VUOPajbyw false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q03717 uniprotkb:Q80ZD8 intact:EBI-7511364|uniprotkb:Q8K0D1|intact:MINT-8298631|ensembl:ENSMUSP00000057981|ensembl:ENSMUSP00000147093 intact:EBI-7511393|uniprotkb:Q69ZQ0|uniprotkb:Q8R5D4|uniprotkb:Q921U9|intact:MINT-8298633|uniprotkb:A2AE40|ensembl:ENSMUSP00000061244|ensembl:ENSMUSP00000102267 psi-mi:kcnb1_mouse(display_long)|uniprotkb:Kcnb1(gene name)|psi-mi:Kcnb1(display_short)|uniprotkb:mShab(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv2.1(gene name synonym) psi-mi:amgo1_mouse(display_long)|uniprotkb:Amigo1(gene name)|psi-mi:Amigo1(display_short)|uniprotkb:AMIGO-1(gene name synonym)|uniprotkb:Ali2(gene name synonym)|uniprotkb:Alivin-2(gene name synonym)|uniprotkb:Kiaa1163(gene name synonym)|uniprotkb:Amigo(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Peltola et al. (2011) pubmed:22056818|imex:IM-16692|mint:MINT-8298551|doi:10.1038/embor.2011.204 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7511545|mint:MINT-8302774|imex:IM-16692-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032446.2|interpro:IPR004350(Potassium channel, voltage dependent, Kv2.1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-381676|refseq:XP_017171221.1|refseq:XP_017171222.1|ensembl:ENSMUSG00000050556(gene)|ensembl:ENSMUST00000059826(transcript)|ensembl:ENSMUST00000207917(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:2000671"(regulation of motor neuron apoptotic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003973(Potassium channel, voltage dependent, Kv2)|mint:MINT-8302776(identity) refseq:NP_001004293.1|refseq:NP_666249.2|ensembl:ENSMUSG00000050947(gene)|ensembl:ENSMUST00000050909(transcript)|ensembl:ENSMUST00000106656(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007409"(axonogenesis)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0106030"(neuron projection fasciculation)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1990030"(pericellular basket)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031283|interpro:IPR031284|interpro:IPR032675|interpro:IPR036179|rcsb pdb:2XOT|refseq:NP_001274022.1|mint:MINT-8302778(identity) - comment:mint comment:mint figure legend:f1d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/12/14 2014/10/16 rogid:bVGBUW1uvAWqGoo7whe/Oa6Wcv010090 rogid:joHgLy+rO442SPPm6IQrQSzFHNw10090 intact-crc:FB7E2CFC08399B58|rigid:LhtmH8UiIxQ0WAPM2Mee5pY9QM0 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)