#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y4E8	uniprotkb:Q9Y4E8	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Elliott et al. (2011)	pubmed:22001210|imex:IM-16797|mint:MINT-8208794|doi:10.1016/j.febslet.2011.09.040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7479199|mint:MINT-8208947|imex:IM-16797-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N|mint:MINT-8208949(identity)	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N|mint:MINT-8208949(identity)	-	comment:"Stoichiometry: 4.0"	comment:"Stoichiometry: 4.0"	figure legend:sf1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/29	2014/10/16	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	intact-crc:E8302293B373F823|rigid:wzV8wyZ07mRM2OeArKl/VNs0fEo	false	binding-associated region:1-223(MINT-8208950)	binding-associated region:1-223(MINT-8208950)	4	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y4E8	uniprotkb:Q9Y4E8	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Elliott et al. (2011)	pubmed:22001210|imex:IM-16797|mint:MINT-8208794|doi:10.1016/j.febslet.2011.09.040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7479154|mint:MINT-8208873|imex:IM-16797-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N|mint:MINT-8208875(identity)	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N|mint:MINT-8208875(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	comment:mint|figure legend:f1b sf1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/29	2014/10/16	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	intact-crc:1A1BC7D30B8CE788|rigid:wzV8wyZ07mRM2OeArKl/VNs0fEo	false	binding-associated region:1-223(MINT-8208897)	binding-associated region:1-223(MINT-8208897)	2	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13107	uniprotkb:Q13107	intact:EBI-723290|uniprotkb:O43452|uniprotkb:O43453|uniprotkb:Q08AK8|ensembl:ENSP00000265560|uniprotkb:A8K6Y0|uniprotkb:C9IY91	intact:EBI-723290|uniprotkb:O43452|uniprotkb:O43453|uniprotkb:Q08AK8|ensembl:ENSP00000265560|uniprotkb:A8K6Y0|uniprotkb:C9IY91	psi-mi:ubp4_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Ubiquitous nuclear protein homolog(gene name synonym)|uniprotkb:USP4(gene name)|psi-mi:USP4(display_short)|uniprotkb:UNP(gene name synonym)|uniprotkb:UNPH(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)	psi-mi:ubp4_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Ubiquitous nuclear protein homolog(gene name synonym)|uniprotkb:USP4(gene name)|psi-mi:USP4(display_short)|uniprotkb:UNP(gene name synonym)|uniprotkb:UNPH(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Elliott et al. (2011)	pubmed:22001210|imex:IM-16797|mint:MINT-8208794|doi:10.1016/j.febslet.2011.09.040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7479291|mint:MINT-8209036|imex:IM-16797-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003354.2|refseq:NP_955475.1|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031685"(adenosine receptor binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR035927|interpro:IPR038765|mint:Q13107|rcsb pdb:2Y6E|rcsb pdb:5CTR|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|ensembl:ENSG00000114316(gene)|ensembl:ENST00000265560(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031397"(negative regulation of protein ubiquitination)|refseq:NP_001238806.1|mint:MINT-8209038(identity)	refseq:NP_003354.2|refseq:NP_955475.1|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031685"(adenosine receptor binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR035927|interpro:IPR038765|mint:Q13107|rcsb pdb:2Y6E|rcsb pdb:5CTR|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|ensembl:ENSG00000114316(gene)|ensembl:ENST00000265560(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031397"(negative regulation of protein ubiquitination)|refseq:NP_001238806.1|mint:MINT-8209038(identity)	-	comment:"Stoichiometry: 4.0"	comment:"Stoichiometry: 4.0"	figure legend:sf1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/29	2014/10/16	rogid:uVbfLYa5ruPa6HBQehcQfXqI22w9606	rogid:uVbfLYa5ruPa6HBQehcQfXqI22w9606	intact-crc:BBBBAD0DA2FE8E33|rigid:jUDf9MeULTX/gGn/S1TFL3RW7uw	false	binding-associated region:1-226(MINT-8209039)	binding-associated region:1-226(MINT-8209039)	4	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13107	uniprotkb:Q13107	intact:EBI-723290|uniprotkb:O43452|uniprotkb:O43453|uniprotkb:Q08AK8|ensembl:ENSP00000265560|uniprotkb:A8K6Y0|uniprotkb:C9IY91	intact:EBI-723290|uniprotkb:O43452|uniprotkb:O43453|uniprotkb:Q08AK8|ensembl:ENSP00000265560|uniprotkb:A8K6Y0|uniprotkb:C9IY91	psi-mi:ubp4_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Ubiquitous nuclear protein homolog(gene name synonym)|uniprotkb:USP4(gene name)|psi-mi:USP4(display_short)|uniprotkb:UNP(gene name synonym)|uniprotkb:UNPH(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)	psi-mi:ubp4_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Ubiquitous nuclear protein homolog(gene name synonym)|uniprotkb:USP4(gene name)|psi-mi:USP4(display_short)|uniprotkb:UNP(gene name synonym)|uniprotkb:UNPH(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Elliott et al. (2011)	pubmed:22001210|imex:IM-16797|mint:MINT-8208794|doi:10.1016/j.febslet.2011.09.040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7479253|mint:MINT-8209008|imex:IM-16797-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003354.2|refseq:NP_955475.1|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031685"(adenosine receptor binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR035927|interpro:IPR038765|mint:Q13107|rcsb pdb:2Y6E|rcsb pdb:5CTR|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|ensembl:ENSG00000114316(gene)|ensembl:ENST00000265560(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031397"(negative regulation of protein ubiquitination)|refseq:NP_001238806.1|mint:MINT-8209010(identity)	refseq:NP_003354.2|refseq:NP_955475.1|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031685"(adenosine receptor binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR035927|interpro:IPR038765|mint:Q13107|rcsb pdb:2Y6E|rcsb pdb:5CTR|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|ensembl:ENSG00000114316(gene)|ensembl:ENST00000265560(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031397"(negative regulation of protein ubiquitination)|refseq:NP_001238806.1|mint:MINT-8209010(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	comment:mint|figure legend:sf1 f1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/29	2014/10/16	rogid:uVbfLYa5ruPa6HBQehcQfXqI22w9606	rogid:uVbfLYa5ruPa6HBQehcQfXqI22w9606	intact-crc:7FB07FB7C1C8C9DB|rigid:jUDf9MeULTX/gGn/S1TFL3RW7uw	false	binding-associated region:1-226(MINT-8209011)	binding-associated region:1-226(MINT-8209011)	2	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P51784	uniprotkb:P51784	intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348	intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348	psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym)	psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Elliott et al. (2011)	pubmed:22001210|imex:IM-16797|mint:MINT-8208794|doi:10.1016/j.febslet.2011.09.040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7479372|mint:MINT-8209165|imex:IM-16797-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102226(gene)|ensembl:ENST00000218348(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:NP_004642.2|refseq:XP_011542290.1|refseq:XP_005272731.1|dip:DIP-27567N|mint:MINT-8209167(identity)	ensembl:ENSG00000102226(gene)|ensembl:ENST00000218348(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:NP_004642.2|refseq:XP_011542290.1|refseq:XP_005272731.1|dip:DIP-27567N|mint:MINT-8209167(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:sf1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/29	2014/10/16	rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606	rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606	intact-crc:8B5796A445B286B9|rigid:uZZMk6YxAV4ws501m8aOjY9axZ4	false	binding-associated region:65-286(MINT-8209168)	binding-associated region:65-286(MINT-8209168)	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y4E8	uniprotkb:Q9Y4E8	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Elliott et al. (2011)	pubmed:22001210|imex:IM-16797|mint:MINT-8208794|doi:10.1016/j.febslet.2011.09.040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7479305|mint:MINT-8209060|imex:IM-16797-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N|mint:MINT-8209062(identity)	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N|mint:MINT-8209062(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:f3b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/29	2014/10/16	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	intact-crc:5EE3FAB9B0641BE7|rigid:wzV8wyZ07mRM2OeArKl/VNs0fEo	false	-	-	2	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y4E8	uniprotkb:Q9Y4E8	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Elliott et al. (2011)	pubmed:22001210|imex:IM-16797|mint:MINT-8208794|doi:10.1016/j.febslet.2011.09.040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7479413|mint:MINT-8209174|imex:IM-16797-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N|mint:MINT-8209176(identity)	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N|mint:MINT-8209176(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	comment:mint|figure legend:t1 f1d sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/29	2014/10/16	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	intact-crc:C830D9CAEB5E293C|rigid:wzV8wyZ07mRM2OeArKl/VNs0fEo	false	binding-associated region:1-223(MINT-8209177)	binding-associated region:1-223(MINT-8209177)	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y4E8	uniprotkb:Q9Y4E8	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Elliott et al. (2011)	pubmed:22001210|imex:IM-16797|mint:MINT-8208794|doi:10.1016/j.febslet.2011.09.040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7479496|mint:MINT-8209187|imex:IM-16797-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N|mint:MINT-8209189(identity)	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N|mint:MINT-8209189(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:sf3b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/29	2014/10/16	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	intact-crc:B073803028B9184B|rigid:wzV8wyZ07mRM2OeArKl/VNs0fEo	false	binding-associated region:1-223(MINT-8209190)	binding-associated region:1-223(MINT-8209190)	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13107	uniprotkb:Q13107	intact:EBI-723290|uniprotkb:O43452|uniprotkb:O43453|uniprotkb:Q08AK8|ensembl:ENSP00000265560|uniprotkb:A8K6Y0|uniprotkb:C9IY91	intact:EBI-723290|uniprotkb:O43452|uniprotkb:O43453|uniprotkb:Q08AK8|ensembl:ENSP00000265560|uniprotkb:A8K6Y0|uniprotkb:C9IY91	psi-mi:ubp4_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Ubiquitous nuclear protein homolog(gene name synonym)|uniprotkb:USP4(gene name)|psi-mi:USP4(display_short)|uniprotkb:UNP(gene name synonym)|uniprotkb:UNPH(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)	psi-mi:ubp4_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Ubiquitous nuclear protein homolog(gene name synonym)|uniprotkb:USP4(gene name)|psi-mi:USP4(display_short)|uniprotkb:UNP(gene name synonym)|uniprotkb:UNPH(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Elliott et al. (2011)	pubmed:22001210|imex:IM-16797|mint:MINT-8208794|doi:10.1016/j.febslet.2011.09.040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7479567|mint:MINT-8209199|imex:IM-16797-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003354.2|refseq:NP_955475.1|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031685"(adenosine receptor binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR035927|interpro:IPR038765|mint:Q13107|rcsb pdb:2Y6E|rcsb pdb:5CTR|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|ensembl:ENSG00000114316(gene)|ensembl:ENST00000265560(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031397"(negative regulation of protein ubiquitination)|refseq:NP_001238806.1|mint:MINT-8209208(identity)	refseq:NP_003354.2|refseq:NP_955475.1|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031685"(adenosine receptor binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR035927|interpro:IPR038765|mint:Q13107|rcsb pdb:2Y6E|rcsb pdb:5CTR|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|ensembl:ENSG00000114316(gene)|ensembl:ENST00000265560(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031397"(negative regulation of protein ubiquitination)|refseq:NP_001238806.1|mint:MINT-8209201(identity)	-	-	-	comment:homomint|comment:mint|figure legend:sf4b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/29	2014/10/16	rogid:uVbfLYa5ruPa6HBQehcQfXqI22w9606	rogid:uVbfLYa5ruPa6HBQehcQfXqI22w9606	intact-crc:FA807DF3C931A69E|rigid:AmpGEJpRo1cUfoSzgrtHzPB+bco	false	binding-associated region:1-226(MINT-8209211)	binding-associated region:1-226(MINT-8209202)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)