#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P50106 uniprotkb:P46669 intact:EBI-15750|uniprotkb:D6VSD7|ensemblfungi:YDR156W intact:EBI-15745|uniprotkb:Q99187|uniprotkb:D6W335|ensemblfungi:YOR340C psi-mi:rpa14_yeast(display_long)|uniprotkb:RPA14(gene name)|psi-mi:RPA14(display_short)|uniprotkb:YDR156W(locus name)|uniprotkb:YD8358.11(orf name)|uniprotkb:DNA-directed RNA polymerase I 14 kDa polypeptide(gene name synonym) psi-mi:rpa43_yeast(display_long)|uniprotkb:RPA43(gene name)|psi-mi:RPA43(display_short)|uniprotkb:RRN12(gene name synonym)|uniprotkb:YOR340C(locus name)|uniprotkb:O6271(orf name)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 36 kDa polypeptide(gene name synonym) psi-mi:"MI:0018"(two hybrid) Beckouët et al. (2011) pubmed:21983101|imex:IM-16782|mint:MINT-8203608|doi:10.1016/j.febslet.2011.09.011 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7468040|mint:MINT-8203618|imex:IM-16782-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010440.1|sgd:S000002563|ensemblfungi:YDR156W(gene)|ensemblfungi:YDR156W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0008361"(regulation of cell size)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013239(RNA polymerase I, subunit RPA14, fungi)|rcsb pdb:2RF4|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:6RWE|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6TPS|dip:DIP-2053N|mint:P50106|mint:MINT-8203621(identity) refseq:NP_014985.1|sgd:S000005867|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|ensemblfungi:YOR340C(gene)|ensemblfungi:YOR340C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR036898|interpro:IPR041178|interpro:IPR041901|rcsb pdb:2RF4|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|dip:DIP-5405N|mint:P46669|mint:MINT-8203620(identity) - crc64:D2318636ABDE68B9 crc64:0CC6421AC3BBC641 comment:mint|figure legend:f3 f4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/09/07 2014/10/16 rogid:fIDAOOpJrLwSXy7vygwP4Cu96Ww559292 rogid:I8xMWRrEe0PhCstGStK44rQD30Q559292 intact-crc:C52CF9C992759DC9|rigid:wtYjcjCzrESMphS3kiuX4gt1uvg false fusion protein:?-?(MINT-8203627) fusion protein:?-?(MINT-8203623) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46669 uniprotkb:P27692 intact:EBI-15745|uniprotkb:Q99187|uniprotkb:D6W335|ensemblfungi:YOR340C intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:rpa43_yeast(display_long)|uniprotkb:RPA43(gene name)|psi-mi:RPA43(display_short)|uniprotkb:RRN12(gene name synonym)|uniprotkb:YOR340C(locus name)|uniprotkb:O6271(orf name)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 36 kDa polypeptide(gene name synonym) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Beckouët et al. (2011) pubmed:21983101|imex:IM-16782|mint:MINT-8203608|doi:10.1016/j.febslet.2011.09.011 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7468162|mint:MINT-8203705|imex:IM-16782-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014985.1|sgd:S000005867|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|ensemblfungi:YOR340C(gene)|ensemblfungi:YOR340C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR036898|interpro:IPR041178|interpro:IPR041901|rcsb pdb:2RF4|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|dip:DIP-5405N|mint:P46669|mint:MINT-8203707(identity) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8203713(identity) - crc64:0CC6421AC3BBC641 crc64:E4324DB6B1E4721A figure legend:f4a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/09/07 2014/10/16 rogid:I8xMWRrEe0PhCstGStK44rQD30Q559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:4585A577310F405E|rigid:/oCFeT14+cImhgjawKcUqQT3h9g false fusion protein:?-?(MINT-8203710) binding-associated region:551-614(MINT-8203714)|fusion protein:?-?(MINT-8203716) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P46669 uniprotkb:P23615 intact:EBI-15745|uniprotkb:Q99187|uniprotkb:D6W335|ensemblfungi:YOR340C intact:EBI-17947|uniprotkb:D6VUP7|ensemblfungi:YGR116W psi-mi:rpa43_yeast(display_long)|uniprotkb:RPA43(gene name)|psi-mi:RPA43(display_short)|uniprotkb:RRN12(gene name synonym)|uniprotkb:YOR340C(locus name)|uniprotkb:O6271(orf name)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 36 kDa polypeptide(gene name synonym) psi-mi:spt6_yeast(display_long)|uniprotkb:CRE2(gene name synonym)|uniprotkb:SPT6(gene name)|psi-mi:SPT6(display_short)|uniprotkb:SSN20(gene name synonym)|uniprotkb:YGR116W(locus name)|uniprotkb:G6169(orf name)|uniprotkb:Chromatin elongation factor SPT6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Beckouët et al. (2011) pubmed:21983101|imex:IM-16782|mint:MINT-8203608|doi:10.1016/j.febslet.2011.09.011 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7468110|mint:MINT-8203632|imex:IM-16782-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014985.1|sgd:S000005867|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|ensemblfungi:YOR340C(gene)|ensemblfungi:YOR340C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR036898|interpro:IPR041178|interpro:IPR041901|rcsb pdb:2RF4|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|dip:DIP-5405N|mint:P46669|mint:MINT-8203634(identity) refseq:NP_011631.1|sgd:S000003348|ensemblfungi:YGR116W(gene)|ensemblfungi:YGR116W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000414"(regulation of histone H3-K36 methylation)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0001073"(transcription antitermination factor activity, DNA binding)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070827"(obsolete chromatin maintenance)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR000980(SH2 motif)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR023319|interpro:IPR023323|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR042066|rcsb pdb:2L3T|rcsb pdb:3OAK|rcsb pdb:3PSF|rcsb pdb:3PSI|rcsb pdb:3PSJ|rcsb pdb:3PSK|rcsb pdb:5VKL|rcsb pdb:5VKO|reactome:R-SCE-674695|reactome:R-SCE-75955|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031564"(transcription antitermination)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|dip:DIP-2630N|mint:P23615|mint:MINT-8203638(identity) - crc64:0CC6421AC3BBC641 crc64:0BE9922A59BD0483 figure legend:f4a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/09/07 2014/10/16 rogid:I8xMWRrEe0PhCstGStK44rQD30Q559292 rogid:P9a7UCjdCVTSPp8jVc5NjDP4FZk559292 intact-crc:33AF0BF1C908E107|rigid:db1I6FAH2sNErKWT37SJZyVY9gA false fusion protein:?-?(MINT-8203635)|binding-associated region:36-280(MINT-8203648) fusion protein:?-?(MINT-8203639)|binding-associated region:1224-1423(MINT-8203645) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03973 uniprotkb:P27692 intact:EBI-33047|uniprotkb:D6VSF6|ensemblfungi:YDR174W intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:hmo1_yeast(display_long)|uniprotkb:HMO1(gene name)|psi-mi:HMO1(display_short)|uniprotkb:High spontaneous mutagenesis protein 2(gene name synonym)|uniprotkb:HSM2(gene name synonym)|uniprotkb:YD9395.07(orf name)|uniprotkb:YDR174W(locus name) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Beckouët et al. (2011) pubmed:21983101|imex:IM-16782|mint:MINT-8203608|doi:10.1016/j.febslet.2011.09.011 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7468226|mint:MINT-8203653|imex:IM-16782-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010459.1|sgd:S000002581|mint:Q03973|dip:DIP-1687N|ensemblfungi:YDR174W(gene)|ensemblfungi:YDR174W_mRNA(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0006323"(DNA packaging)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0060962"(regulation of ribosomal protein gene transcription by RNA polymerase II)|go:"GO:0070550"(rDNA condensation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|mint:MINT-8203655(identity) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8203661(identity) go:"GO:0005730"(nucleolus) crc64:3D6DCD56A28B7D77 crc64:E4324DB6B1E4721A figure legend:f4b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/09/07 2014/10/16 rogid:9sHGPuUbReXRmvQYqKvnd4fWBd4559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:63AE3361E7FCE620|rigid:uqHlPQCYRy+sNgROlgqZR0bu9hI false cyan fluorescent protein tag:?-?(MINT-8203658) trapping mutant:?-?(MINT-8203852)|yellow fluorescent protein tag:?-?(MINT-8203664) - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q03973 uniprotkb:P23615 intact:EBI-33047|uniprotkb:D6VSF6|ensemblfungi:YDR174W intact:EBI-17947|uniprotkb:D6VUP7|ensemblfungi:YGR116W psi-mi:hmo1_yeast(display_long)|uniprotkb:HMO1(gene name)|psi-mi:HMO1(display_short)|uniprotkb:High spontaneous mutagenesis protein 2(gene name synonym)|uniprotkb:HSM2(gene name synonym)|uniprotkb:YD9395.07(orf name)|uniprotkb:YDR174W(locus name) psi-mi:spt6_yeast(display_long)|uniprotkb:CRE2(gene name synonym)|uniprotkb:SPT6(gene name)|psi-mi:SPT6(display_short)|uniprotkb:SSN20(gene name synonym)|uniprotkb:YGR116W(locus name)|uniprotkb:G6169(orf name)|uniprotkb:Chromatin elongation factor SPT6(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Beckouët et al. (2011) pubmed:21983101|imex:IM-16782|mint:MINT-8203608|doi:10.1016/j.febslet.2011.09.011 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7468248|mint:MINT-8203677|imex:IM-16782-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010459.1|sgd:S000002581|mint:Q03973|dip:DIP-1687N|ensemblfungi:YDR174W(gene)|ensemblfungi:YDR174W_mRNA(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0006323"(DNA packaging)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0060962"(regulation of ribosomal protein gene transcription by RNA polymerase II)|go:"GO:0070550"(rDNA condensation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|mint:MINT-8203684(identity) refseq:NP_011631.1|sgd:S000003348|ensemblfungi:YGR116W(gene)|ensemblfungi:YGR116W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000414"(regulation of histone H3-K36 methylation)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0001073"(transcription antitermination factor activity, DNA binding)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070827"(obsolete chromatin maintenance)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR000980(SH2 motif)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR023319|interpro:IPR023323|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR042066|rcsb pdb:2L3T|rcsb pdb:3OAK|rcsb pdb:3PSF|rcsb pdb:3PSI|rcsb pdb:3PSJ|rcsb pdb:3PSK|rcsb pdb:5VKL|rcsb pdb:5VKO|reactome:R-SCE-674695|reactome:R-SCE-75955|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031564"(transcription antitermination)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|dip:DIP-2630N|mint:P23615|mint:MINT-8203680(identity) go:"GO:0005730"(nucleolus) crc64:3D6DCD56A28B7D77 crc64:0BE9922A59BD0483 figure legend:f4b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/09/07 2014/10/16 rogid:9sHGPuUbReXRmvQYqKvnd4fWBd4559292 rogid:P9a7UCjdCVTSPp8jVc5NjDP4FZk559292 intact-crc:3658476F2BBC4C5A|rigid:Tj8c9SP7p+i4+vXwRAesmAq8Avk false cyan fluorescent protein tag:?-?(MINT-8203685) yellow fluorescent protein tag:?-?(MINT-8203690) - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)