#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P59103 uniprotkb:O35078 intact:EBI-7465779|intact:MINT-8204618|uniprotkb:A6NKG7|uniprotkb:Q5VX59|uniprotkb:Q8IWM4|uniprotkb:Q86Y17|uniprotkb:Q0VAE6|ensembl:ENSP00000365103|ensembl:ENSP00000483757 intact:EBI-7465746|intact:MINT-4582363 psi-mi:daoa_human(display_long)|uniprotkb:DAOA(gene name)|psi-mi:DAOA(display_short)|uniprotkb:G72(gene name synonym)|uniprotkb:Protein G72(gene name synonym) psi-mi:oxda_rat(display_long)|uniprotkb:Dao(gene name)|psi-mi:Dao(display_short)|uniprotkb:Dao1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Frattini et al. (2011) pubmed:21981077|imex:IM-16784|mint:MINT-8204578|doi:10.1111/j.1742-4658.2011.08354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7465772|mint:MINT-8204583|imex:IM-16784-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_758958.3|refseq:NP_001155286.1|refseq:NP_001155284.1|refseq:XP_005254099.1|ensembl:ENSG00000182346(gene)|ensembl:ENST00000375936(transcript)|ensembl:ENST00000618629(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1900758"(negative regulation of D-amino-acid oxidase activity)|interpro:IPR027929|mint:MINT-8204633(identity) refseq:NP_446078.1|interpro:IPR023209|rgd:621138|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR006181(D-amino acid oxidase, conserved site)|go:"GO:0003884"(D-amino-acid oxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006551"(leucine metabolic process)|go:"GO:0006562"(proline catabolic process)|go:"GO:0019478"(D-amino acid catabolic process)|go:"GO:0036088"(D-serine catabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055130"(D-alanine catabolic process)|go:"GO:0070178"(D-serine metabolic process)|go:"GO:0071949"(FAD binding)|reactome:R-RNO-389661|reactome:R-RNO-9033241|mint:MINT-8204585(identity) - comment:mint comment:mint|function:Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids figure legend:f2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/09/13 2014/10/16 rogid:hjJHMslHP0dXgDZSbDEOQScXZME9606 rogid:/ZsAE+5nFCnoUmQ1A75Ic1zBeIo10116 intact-crc:131A32FB5AF3945E|rigid:eM5Tgm/ACdRJOpJyqiaCtAfwrOk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)