#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P05205 uniprotkb:Q9V629 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 intact:EBI-185996|uniprotkb:Q29QR5|ensemblmetazoa:FBpp0087141 psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:cuff_drome(display_long)|uniprotkb:CG13190(orf name)|uniprotkb:cuff(gene name)|psi-mi:cuff(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Pane et al. (2011) pubmed:21952049|imex:IM-16669|mint:MINT-8300380|doi:10.1038/emboj.2011.334 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7453821|mint:MINT-8300387|imex:IM-16669-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA|mint:MINT-8300390(identity) refseq:NP_610709.1|flybase:FBgn0260932|ensemblmetazoa:FBgn0260932(gene)|ensemblmetazoa:FBtr0088034(transcript)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0030719"(P granule organization)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0110155"(NAD-cap decapping)|interpro:IPR013961(RAI1 like)|interpro:IPR039039|mint:MINT-8300389(identity) go:"GO:0000792"(heterochromatin) - - comment:homomint|comment:mint|figure legend:f2 sf2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2011/12/20 2014/10/16 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 rogid:7h0b7p+nuHAaGQlxd5Zdmif2FE87227 intact-crc:59526568D517215D|rigid:6d8cbDZTWykJy5LB+qTH38PHgkc false - green fluorescent protein tag:?-?(MINT-8300453) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9V629 uniprotkb:Q7JXA8 intact:EBI-185996|uniprotkb:Q29QR5|ensemblmetazoa:FBpp0087141 intact:EBI-149916|intact:EBI-3435595|ensemblmetazoa:FBpp0086056 psi-mi:cuff_drome(display_long)|uniprotkb:CG13190(orf name)|uniprotkb:cuff(gene name)|psi-mi:cuff(display_short) psi-mi:q7jxa8_drome(display_long)|uniprotkb:rhi(gene name)|psi-mi:rhi(display_short)|uniprotkb:rhino(gene name synonym)|uniprotkb:hp1d(gene name synonym)|uniprotkb:Dmel\CG10683(gene name synonym)|uniprotkb:HP1(gene name synonym)|uniprotkb:HP1D(gene name synonym)|uniprotkb:HP1d(gene name synonym)|uniprotkb:RHI(gene name synonym)|uniprotkb:Rhi(gene name synonym)|uniprotkb:Rhino(gene name synonym)|uniprotkb:rno(gene name synonym)|uniprotkb:CG10683(orf name)|uniprotkb:Dmel_CG10683(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Pane et al. (2011) pubmed:21952049|imex:IM-16669|mint:MINT-8300380|doi:10.1038/emboj.2011.334 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7453870|mint:MINT-8300426|imex:IM-16669-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610709.1|flybase:FBgn0260932|ensemblmetazoa:FBgn0260932(gene)|ensemblmetazoa:FBtr0088034(transcript)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0030719"(P granule organization)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0110155"(NAD-cap decapping)|interpro:IPR013961(RAI1 like)|interpro:IPR039039|mint:MINT-8300428(identity) refseq:NP_536794.1|flybase:FBgn0004400|rcsb pdb:4U68|rcsb pdb:5XYV|ensemblmetazoa:FBgn0004400(gene)|ensemblmetazoa:FBtr0086897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051276"(chromosome organization)|go:"GO:1990511"(piRNA biosynthetic process)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|rcsb pdb:4QUC|rcsb pdb:4QUF|mint:MINT-8300432(identity) go:"GO:0005634"(nucleus) - - figure legend:f6c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2011/12/20 2014/10/16 rogid:7h0b7p+nuHAaGQlxd5Zdmif2FE87227 rogid:ZGKMauV68YqFryuQChiply4lsRU7227 intact-crc:5B787C56BA88A02A|rigid:cnO09/WiBwLtT33dp7+G+CoIbb8 false green fluorescent protein tag:?-?(MINT-8300429) - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9V6Q2 uniprotkb:Q9V629 intact:EBI-129287|uniprotkb:Q7YUD4|uniprotkb:Q7YUD5|uniprotkb:Q8MQP5|uniprotkb:Q9NG62|ensemblmetazoa:FBpp0086787 intact:EBI-185996|uniprotkb:Q29QR5|ensemblmetazoa:FBpp0087141 psi-mi:cid_drome(display_long)|uniprotkb:cid(gene name)|psi-mi:cid(display_short)|uniprotkb:CG13329(orf name)|uniprotkb:Centromere identifier protein(gene name synonym)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:CENP-A(gene name synonym) psi-mi:cuff_drome(display_long)|uniprotkb:CG13190(orf name)|uniprotkb:cuff(gene name)|psi-mi:cuff(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Pane et al. (2011) pubmed:21952049|imex:IM-16669|mint:MINT-8300380|doi:10.1038/emboj.2011.334 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7453853|mint:MINT-8300391|imex:IM-16669-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523730.2|flybase:FBgn0040477|ensemblmetazoa:FBgn0040477(gene)|ensemblmetazoa:FBtr0087667(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000939"(inner kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:6XWS|rcsb pdb:6XWT|dip:DIP-29506N|mint:MINT-8300394(identity) refseq:NP_610709.1|flybase:FBgn0260932|ensemblmetazoa:FBgn0260932(gene)|ensemblmetazoa:FBtr0088034(transcript)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0030719"(P granule organization)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0110155"(NAD-cap decapping)|interpro:IPR013961(RAI1 like)|interpro:IPR039039|mint:MINT-8300393(identity) go:"GO:0000775"(chromosome, centromeric region) - - comment:homomint|comment:mint|figure legend:f2 sf2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2011/12/20 2014/10/16 rogid:TReqSvDFVumKoiYPMe0tMrxzcEA7227 rogid:7h0b7p+nuHAaGQlxd5Zdmif2FE87227 intact-crc:0F90FD0EB553BFBB|rigid:jvK5RyhDT/MjEx+W+NdFfqo352U false - green fluorescent protein tag:?-?(MINT-8300444) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9V629 uniprotkb:Q7JXA8 intact:EBI-185996|uniprotkb:Q29QR5|ensemblmetazoa:FBpp0087141 intact:EBI-149916|intact:EBI-3435595|ensemblmetazoa:FBpp0086056 psi-mi:cuff_drome(display_long)|uniprotkb:CG13190(orf name)|uniprotkb:cuff(gene name)|psi-mi:cuff(display_short) psi-mi:q7jxa8_drome(display_long)|uniprotkb:rhi(gene name)|psi-mi:rhi(display_short)|uniprotkb:rhino(gene name synonym)|uniprotkb:hp1d(gene name synonym)|uniprotkb:Dmel\CG10683(gene name synonym)|uniprotkb:HP1(gene name synonym)|uniprotkb:HP1D(gene name synonym)|uniprotkb:HP1d(gene name synonym)|uniprotkb:RHI(gene name synonym)|uniprotkb:Rhi(gene name synonym)|uniprotkb:Rhino(gene name synonym)|uniprotkb:rno(gene name synonym)|uniprotkb:CG10683(orf name)|uniprotkb:Dmel_CG10683(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pane et al. (2011) pubmed:21952049|imex:IM-16669|mint:MINT-8300380|doi:10.1038/emboj.2011.334 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7453895|mint:MINT-8300412|imex:IM-16669-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610709.1|flybase:FBgn0260932|ensemblmetazoa:FBgn0260932(gene)|ensemblmetazoa:FBtr0088034(transcript)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0030719"(P granule organization)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0110155"(NAD-cap decapping)|interpro:IPR013961(RAI1 like)|interpro:IPR039039|mint:MINT-8300414(identity) refseq:NP_536794.1|flybase:FBgn0004400|rcsb pdb:4U68|rcsb pdb:5XYV|ensemblmetazoa:FBgn0004400(gene)|ensemblmetazoa:FBtr0086897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051276"(chromosome organization)|go:"GO:1990511"(piRNA biosynthetic process)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|rcsb pdb:4QUC|rcsb pdb:4QUF|mint:MINT-8300415(identity) - - - figure legend:f6d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2011/12/20 2014/10/16 rogid:7h0b7p+nuHAaGQlxd5Zdmif2FE87227 rogid:ZGKMauV68YqFryuQChiply4lsRU7227 intact-crc:74C21F64AAF7BD09|rigid:cnO09/WiBwLtT33dp7+G+CoIbb8 false green fluorescent protein tag:?-?(MINT-8300421) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot)