#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P08775 ensembl:ENSMUSG00000038793 intact:EBI-2549849|ensembl:ENSMUSP00000050771|uniprotkb:Q5F298 intact:EBI-4412628 psi-mi:rpb1_mouse(display_long)|uniprotkb:Polr2a(gene name)|psi-mi:Polr2a(display_short)|uniprotkb:Rpii215(gene name synonym)|uniprotkb:Rpo2-1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym) psi-mi:lfty1_mouse_gene(display_short)|psi-mi:ENSMUSG00000038793(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4412643|imex:IM-16573-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000005198(gene)|ensembl:ENSMUST00000058470(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|mint:P08775|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|reactome:R-MMU-112382|refseq:NP_001277997.1|dip:DIP-46369N - - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 rogid:kUX/HdU6Y2VHAGjySBcOxfS08XA10090 - intact-crc:60BC058A73D62A32 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000038793 uniprotkb:Q61164 intact:EBI-4412628 intact:EBI-932785|ensembl:ENSMUSP00000005841 psi-mi:lfty1_mouse_gene(display_short)|psi-mi:ENSMUSG00000038793(display_long) psi-mi:ctcf_mouse(display_long)|uniprotkb:Ctcf(gene name)|psi-mi:Ctcf(display_short)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4412638|imex:IM-16573-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_851839.1|refseq:XP_006530711.1|dip:DIP-38020N|ensembl:ENSMUSG00000005698(gene)|ensembl:ENSMUST00000005841(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q61164|reactome:R-MMU-212436 - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 - rogid:r9BpKoiLzrCAiQttYFbIIkitePk10090 intact-crc:FC748306E80999D5 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5HZG4 ensembl:ENSMUSG00000038793 intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888 intact:EBI-4412628 psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short) psi-mi:lfty1_mouse_gene(display_short)|psi-mi:ENSMUSG00000038793(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4412630|imex:IM-16573-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042 - - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090 - intact-crc:0A5E350F3B1CED11 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000021944 uniprotkb:P20263 intact:EBI-1790676 intact:EBI-1606219|uniprotkb:Q63843|ensembl:ENSMUSP00000025271 psi-mi:gata4_mouse_gene(display_short)|psi-mi:ENSMUSG00000021944(display_long) psi-mi:po5f1_mouse(display_long)|uniprotkb:Pou5f1(gene name)|psi-mi:Pou5f1(display_short)|uniprotkb:Oct-3(gene name synonym)|uniprotkb:Oct-4(gene name synonym)|uniprotkb:Otf-3(gene name synonym)|uniprotkb:Otf3(gene name synonym)|uniprotkb:Octamer-binding transcription factor 3(gene name synonym)|uniprotkb:NF-A3(gene name synonym)|uniprotkb:Octamer-binding protein 3(gene name synonym)|uniprotkb:Octamer-binding protein 4(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4412566|imex:IM-16573-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_038661.2|ensembl:ENSMUSG00000024406(gene)|ensembl:ENSMUST00000025271(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001824"(blastocyst development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003130"(BMP signaling pathway involved in heart induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010033"(response to organic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019955"(cytokine binding)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0005730"(nucleolus)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060795"(cell fate commitment involved in formation of primary germ layer)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0005737"(cytoplasm)|go:"GO:0070974"(POU domain binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090081"(regulation of heart induction by regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090308"(regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000327(POU-specific)|go:"GO:0005739"(mitochondrion)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR015585(POU domain class 5)|interpro:IPR017970|rcsb pdb:1OCP|rcsb pdb:3L1P|rcsb pdb:6HT5|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|dip:DIP-29931N - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 - rogid:AA1LwlLApjnKYcDk+3DoqicIRlk10090 intact-crc:EFFEE62B2DFA92AE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P08775 ensembl:ENSMUSG00000021944 intact:EBI-2549849|ensembl:ENSMUSP00000050771|uniprotkb:Q5F298 intact:EBI-1790676 psi-mi:rpb1_mouse(display_long)|uniprotkb:Polr2a(gene name)|psi-mi:Polr2a(display_short)|uniprotkb:Rpii215(gene name synonym)|uniprotkb:Rpo2-1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym) psi-mi:gata4_mouse_gene(display_short)|psi-mi:ENSMUSG00000021944(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4412576|imex:IM-16573-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000005198(gene)|ensembl:ENSMUST00000058470(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|mint:P08775|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|reactome:R-MMU-112382|refseq:NP_001277997.1|dip:DIP-46369N - - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 rogid:kUX/HdU6Y2VHAGjySBcOxfS08XA10090 - intact-crc:A2817DE0BA14D135 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29037 ensembl:ENSMUSG00000038793 intact:EBI-4399956|uniprotkb:O09169|uniprotkb:Q80UL8|uniprotkb:Q8C3S1|ensembl:ENSMUSP00000014911|ensembl:ENSMUSP00000112794|ensembl:ENSMUSP00000124317 intact:EBI-4412628 psi-mi:tbp_mouse(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:Tfiid(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:lfty1_mouse_gene(display_short)|psi-mi:ENSMUSG00000038793(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4412634|imex:IM-16573-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_038712.3|dip:DIP-24197N|ensembl:ENSMUSG00000014767(gene)|ensembl:ENSMUST00000014911(transcript)|ensembl:ENSMUST00000117593(transcript)|ensembl:ENSMUST00000162505(transcript)|go:"GO:0000120"(RNA polymerase I transcription regulator complex)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045120"(pronucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-MMU-5250924|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|reactome:R-MMU-9018519 - - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 rogid:Rv5vNIOGEhlaWS1woZqBFiuf5pg10090 - intact-crc:29E8435031091282 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000021944 uniprotkb:Q5HZG4 intact:EBI-1790676 intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888 psi-mi:gata4_mouse_gene(display_short)|psi-mi:ENSMUSG00000021944(display_long) psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4412620|imex:IM-16573-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042 - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 - rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090 intact-crc:C8634D65F2DE1616 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000021944 uniprotkb:Q61164 intact:EBI-1790676 intact:EBI-932785|ensembl:ENSMUSP00000005841 psi-mi:gata4_mouse_gene(display_short)|psi-mi:ENSMUSG00000021944(display_long) psi-mi:ctcf_mouse(display_long)|uniprotkb:Ctcf(gene name)|psi-mi:Ctcf(display_short)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4412572|imex:IM-16573-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_851839.1|refseq:XP_006530711.1|dip:DIP-38020N|ensembl:ENSMUSG00000005698(gene)|ensembl:ENSMUST00000005841(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q61164|reactome:R-MMU-212436 - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 - rogid:r9BpKoiLzrCAiQttYFbIIkitePk10090 intact-crc:3E49FB6C21CB62D2 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000021944 uniprotkb:P29037 intact:EBI-1790676 intact:EBI-4399956|uniprotkb:O09169|uniprotkb:Q80UL8|uniprotkb:Q8C3S1|ensembl:ENSMUSP00000014911|ensembl:ENSMUSP00000112794|ensembl:ENSMUSP00000124317 psi-mi:gata4_mouse_gene(display_short)|psi-mi:ENSMUSG00000021944(display_long) psi-mi:tbp_mouse(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:Tfiid(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4412608|imex:IM-16573-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_038712.3|dip:DIP-24197N|ensembl:ENSMUSG00000014767(gene)|ensembl:ENSMUST00000014911(transcript)|ensembl:ENSMUST00000117593(transcript)|ensembl:ENSMUST00000162505(transcript)|go:"GO:0000120"(RNA polymerase I transcription regulator complex)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045120"(pronucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-MMU-5250924|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|reactome:R-MMU-9018519 - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 - rogid:Rv5vNIOGEhlaWS1woZqBFiuf5pg10090 intact-crc:EBD53B3AF8CBE985 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000038793 uniprotkb:P20263 intact:EBI-4412628 intact:EBI-1606219|uniprotkb:Q63843|ensembl:ENSMUSP00000025271 psi-mi:lfty1_mouse_gene(display_short)|psi-mi:ENSMUSG00000038793(display_long) psi-mi:po5f1_mouse(display_long)|uniprotkb:Pou5f1(gene name)|psi-mi:Pou5f1(display_short)|uniprotkb:Oct-3(gene name synonym)|uniprotkb:Oct-4(gene name synonym)|uniprotkb:Otf-3(gene name synonym)|uniprotkb:Otf3(gene name synonym)|uniprotkb:Octamer-binding transcription factor 3(gene name synonym)|uniprotkb:NF-A3(gene name synonym)|uniprotkb:Octamer-binding protein 3(gene name synonym)|uniprotkb:Octamer-binding protein 4(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4412647|imex:IM-16573-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_038661.2|ensembl:ENSMUSG00000024406(gene)|ensembl:ENSMUST00000025271(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001824"(blastocyst development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003130"(BMP signaling pathway involved in heart induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010033"(response to organic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019955"(cytokine binding)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0005730"(nucleolus)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060795"(cell fate commitment involved in formation of primary germ layer)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0005737"(cytoplasm)|go:"GO:0070974"(POU domain binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090081"(regulation of heart induction by regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090308"(regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000327(POU-specific)|go:"GO:0005739"(mitochondrion)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR015585(POU domain class 5)|interpro:IPR017970|rcsb pdb:1OCP|rcsb pdb:3L1P|rcsb pdb:6HT5|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|dip:DIP-29931N - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 - rogid:AA1LwlLApjnKYcDk+3DoqicIRlk10090 intact-crc:2DC39E41E43869A9 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49711 uniprotkb:Q5HZG4 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4399997|imex:IM-16573-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/09/13 2014/10/16 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090 intact-crc:DED8C59D29F01BAD|rigid:u9bkYpQBzdpsm+gWqYJXGI+u33Q false - flag tag:?-?|ha tag:?-?|sufficient binding region:501-730 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5HZG4 uniprotkb:P29037 intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888 intact:EBI-4399956|uniprotkb:O09169|uniprotkb:Q80UL8|uniprotkb:Q8C3S1|ensembl:ENSMUSP00000014911|ensembl:ENSMUSP00000112794|ensembl:ENSMUSP00000124317 psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short) psi-mi:tbp_mouse(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:Tfiid(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4399955|imex:IM-16573-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042 refseq:NP_038712.3|dip:DIP-24197N|ensembl:ENSMUSG00000014767(gene)|ensembl:ENSMUST00000014911(transcript)|ensembl:ENSMUST00000117593(transcript)|ensembl:ENSMUST00000162505(transcript)|go:"GO:0000120"(RNA polymerase I transcription regulator complex)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045120"(pronucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-MMU-5250924|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|reactome:R-MMU-9018519 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 7A|comment:Interactions occur in the absence of DNA|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090 rogid:Rv5vNIOGEhlaWS1woZqBFiuf5pg10090 intact-crc:D4D38AD984A7E6C5|rigid:pKOKOeWG2NfZUjkk6GVplparqN4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5HZG4 uniprotkb:Q61164 intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888 intact:EBI-932785|ensembl:ENSMUSP00000005841 psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short) psi-mi:ctcf_mouse(display_long)|uniprotkb:Ctcf(gene name)|psi-mi:Ctcf(display_short)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21884934|imex:IM-16573 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4399955|imex:IM-16573-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042 refseq:NP_851839.1|refseq:XP_006530711.1|dip:DIP-38020N|ensembl:ENSMUSG00000005698(gene)|ensembl:ENSMUST00000005841(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q61164|reactome:R-MMU-212436 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 7A|comment:Interactions occur in the absence of DNA|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/09/13 2014/10/16 rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090 rogid:r9BpKoiLzrCAiQttYFbIIkitePk10090 intact-crc:D4D38AD984A7E6C5|rigid:pKOKOeWG2NfZUjkk6GVplparqN4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)