#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P18481	uniprotkb:P18481	intact:EBI-5260395|uniprotkb:Q5XE68|ensemblbacteria:AAT86295	intact:EBI-5260395|uniprotkb:Q5XE68|ensemblbacteria:AAT86295	psi-mi:tee6_strp6(display_long)|uniprotkb:tee6(gene name)|psi-mi:tee6(display_short)|uniprotkb:T6 antigen(gene name synonym)|uniprotkb:M6_Spy0160(locus name)	psi-mi:tee6_strp6(display_long)|uniprotkb:tee6(gene name)|psi-mi:tee6(display_short)|uniprotkb:T6 antigen(gene name synonym)|uniprotkb:M6_Spy0160(locus name)	psi-mi:"MI:0808"(comigration in sds page)	Nakata et al. (2011)	pubmed:21880740|imex:IM-17255|mint:MINT-8293895	taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)")	taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5260412|imex:IM-17255-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_021340359.1|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032334|rcsb pdb:4P0D|interpro:IPR019931|interpro:IPR041033|interpro:IPR041184|ensemblbacteria:AAT86295(transcript)|ensemblbacteria:M6_Spy0160(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)	refseq:WP_021340359.1|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032334|rcsb pdb:4P0D|interpro:IPR019931|interpro:IPR041033|interpro:IPR041184|ensemblbacteria:AAT86295(transcript)|ensemblbacteria:M6_Spy0160(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)	go:"GO:0005618"(cell wall)	-	-	figure legend:Fig. 2, 3, 4, 5, 6, Supp. Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)")	-	2011/11/15	2014/10/16	rogid:RfvvAWUEXZdws6wQWF8kjNgl1ls286636	rogid:RfvvAWUEXZdws6wQWF8kjNgl1ls286636	intact-crc:339096B1F4AE0050|rigid:3ZLal1U/h1u/sxUalzkwfhITsYk	false	necessary binding region:505-507|mutation decreasing interaction:163-163|mutation increasing interaction:507-507	mutation increasing interaction:507-507|necessary binding region:505-507|mutation decreasing interaction:163-163	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18481	uniprotkb:Q5XE69	intact:EBI-5260395|uniprotkb:Q5XE68|ensemblbacteria:AAT86295	intact:EBI-5260633|ensemblbacteria:AAT86294	psi-mi:tee6_strp6(display_long)|uniprotkb:tee6(gene name)|psi-mi:tee6(display_short)|uniprotkb:T6 antigen(gene name synonym)|uniprotkb:M6_Spy0160(locus name)	psi-mi:q5xe69_strp6(display_long)|uniprotkb:M6_Spy0159(locus name)	psi-mi:"MI:0808"(comigration in sds page)	Nakata et al. (2011)	pubmed:21880740|imex:IM-17255|mint:MINT-8293895	taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)")	taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5260646|imex:IM-17255-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_021340359.1|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032334|rcsb pdb:4P0D|interpro:IPR019931|interpro:IPR041033|interpro:IPR041184|ensemblbacteria:AAT86295(transcript)|ensemblbacteria:M6_Spy0160(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)	interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|refseq:WP_011184102.1|interpro:IPR041033|ensemblbacteria:AAT86294(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:M6_Spy0159(gene)	go:"GO:0005618"(cell wall)	-	-	figure legend:Fig. 2, 3, 4, 5, 6, Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)")	-	2011/11/15	2014/10/16	rogid:RfvvAWUEXZdws6wQWF8kjNgl1ls286636	rogid:hV66VmcXqULTAhXFwnXRsani+qQ286636	intact-crc:15518FF6B8416A47|rigid:oOMZN0Hd9KOU+z61fXboTPlYkf8	false	mutation decreasing interaction:507-507|mutation decreasing interaction:163-163	necessary binding region:1002-1004|mutation increasing interaction:1004-1004	2	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18481	uniprotkb:Q5XE69	intact:EBI-5260395|uniprotkb:Q5XE68|ensemblbacteria:AAT86295	intact:EBI-5260633|ensemblbacteria:AAT86294	psi-mi:tee6_strp6(display_long)|uniprotkb:tee6(gene name)|psi-mi:tee6(display_short)|uniprotkb:T6 antigen(gene name synonym)|uniprotkb:M6_Spy0160(locus name)	psi-mi:q5xe69_strp6(display_long)|uniprotkb:M6_Spy0159(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nakata et al. (2011)	pubmed:21880740|imex:IM-17255|mint:MINT-8293895	taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)")	taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5260818|imex:IM-17255-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_021340359.1|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032334|rcsb pdb:4P0D|interpro:IPR019931|interpro:IPR041033|interpro:IPR041184|ensemblbacteria:AAT86295(transcript)|ensemblbacteria:M6_Spy0160(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)	interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|refseq:WP_011184102.1|interpro:IPR041033|ensemblbacteria:AAT86294(transcript)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:M6_Spy0159(gene)	go:"GO:0005618"(cell wall)	-	-	figure legend:Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:286636(strp6)|taxid:286636("Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)")	-	2011/11/15	2014/10/16	rogid:RfvvAWUEXZdws6wQWF8kjNgl1ls286636	rogid:hV66VmcXqULTAhXFwnXRsani+qQ286636	intact-crc:980EAF9F54202E68|rigid:oOMZN0Hd9KOU+z61fXboTPlYkf8	false	-	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)