#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5SJ83 uniprotkb:Q5SJ83 intact:EBI-7080155|ensemblbacteria:BAD70954|intact:MINT-8299766 intact:EBI-7080155|ensemblbacteria:BAD70954|intact:MINT-8299766 psi-mi:q5sj83_thet8(display_long)|uniprotkb:TTHA1131(locus name) psi-mi:q5sj83_thet8(display_long)|uniprotkb:TTHA1131(locus name) psi-mi:"MI:0114"(x-ray crystallography) Miertzschke et al. (2011) doi:10.1038/emboj.2011.291|pubmed:21847100|imex:IM-16684|mint:MINT-8296294 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7080176|mint:MINT-8299540|imex:IM-16684-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011228460.1|ensemblbacteria:BAD70954(gene)|ensemblbacteria:BAD70954(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060090"(molecular adaptor activity)|rcsb pdb:3T12|rcsb pdb:3T1R|rcsb pdb:3T1X|rcsb pdb:3T1Q|interpro:IPR004942(Dynein light chain-related)|rcsb pdb:3T1S|refseq:YP_144397.1|interpro:IPR037587|mint:MINT-8299543(identity) refseq:WP_011228460.1|ensemblbacteria:BAD70954(gene)|ensemblbacteria:BAD70954(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060090"(molecular adaptor activity)|rcsb pdb:3T12|rcsb pdb:3T1R|rcsb pdb:3T1X|rcsb pdb:3T1Q|interpro:IPR004942(Dynein light chain-related)|rcsb pdb:3T1S|refseq:YP_144397.1|interpro:IPR037587|mint:MINT-8299543(identity) - comment:mint|comment:"Stoichiometry: 2.0" comment:mint|comment:"Stoichiometry: 2.0" comment:mint|figure legend:st1 st2 sf3b sf4 f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/16 2014/10/16 rogid:KhBKIAFrmcrSbj87wTsoBE0fDgY300852 rogid:KhBKIAFrmcrSbj87wTsoBE0fDgY300852 intact-crc:C78D7F9F5CBD04EF|rigid:eRzqn4j7wO1fXicpQcjWJIjq2FM false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5SJ82 uniprotkb:Q5SJ83 intact:EBI-7080132|ensemblbacteria:BAD70955|intact:MINT-8299764 intact:EBI-7080155|ensemblbacteria:BAD70954|intact:MINT-8299766 psi-mi:q5sj82_thet8(display_long)|uniprotkb:TTHA1132(locus name) psi-mi:q5sj83_thet8(display_long)|uniprotkb:TTHA1131(locus name) psi-mi:"MI:0114"(x-ray crystallography) Miertzschke et al. (2011) doi:10.1038/emboj.2011.291|pubmed:21847100|imex:IM-16684|mint:MINT-8296294 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7080149|mint:MINT-8299535|imex:IM-16684-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011228461.1|ensemblbacteria:BAD70955(gene)|ensemblbacteria:BAD70955(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|rcsb pdb:3T1V|interpro:IPR027417|interpro:IPR006689(ARF/SAR superfamily)|rcsb pdb:3T1T|rcsb pdb:3T12|rcsb pdb:3T1O|refseq:YP_144398.1|rcsb pdb:3T1Q|mint:MINT-8299537(identity) refseq:WP_011228460.1|ensemblbacteria:BAD70954(gene)|ensemblbacteria:BAD70954(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060090"(molecular adaptor activity)|rcsb pdb:3T12|rcsb pdb:3T1R|rcsb pdb:3T1X|rcsb pdb:3T1Q|interpro:IPR004942(Dynein light chain-related)|rcsb pdb:3T1S|refseq:YP_144397.1|interpro:IPR037587|mint:MINT-8299538(identity) - comment:mint|comment:"Stoichiometry: 1.2" comment:mint|comment:"Stoichiometry: 2.1" comment:mint|figure legend:f3a sf1 sf3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/16 2022/01/21 rogid:G2QmsiUZkR/iAPkZUqrwqbpjSRI300852 rogid:KhBKIAFrmcrSbj87wTsoBE0fDgY300852 intact-crc:AD3CE2BFA53A9FBC|rigid:IOZx7lzs5TVo1dlDhxP5DLGWd+4 false - - 1 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5SJ83 uniprotkb:Q5SJ83 intact:EBI-7080155|ensemblbacteria:BAD70954|intact:MINT-8299766 intact:EBI-7080155|ensemblbacteria:BAD70954|intact:MINT-8299766 psi-mi:q5sj83_thet8(display_long)|uniprotkb:TTHA1131(locus name) psi-mi:q5sj83_thet8(display_long)|uniprotkb:TTHA1131(locus name) psi-mi:"MI:0114"(x-ray crystallography) Miertzschke et al. (2011) doi:10.1038/emboj.2011.291|pubmed:21847100|imex:IM-16684|mint:MINT-8296294 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7080196|mint:MINT-8299563|imex:IM-16684-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011228460.1|ensemblbacteria:BAD70954(gene)|ensemblbacteria:BAD70954(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060090"(molecular adaptor activity)|rcsb pdb:3T12|rcsb pdb:3T1R|rcsb pdb:3T1X|rcsb pdb:3T1Q|interpro:IPR004942(Dynein light chain-related)|rcsb pdb:3T1S|refseq:YP_144397.1|interpro:IPR037587|mint:MINT-8299565(identity) refseq:WP_011228460.1|ensemblbacteria:BAD70954(gene)|ensemblbacteria:BAD70954(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060090"(molecular adaptor activity)|rcsb pdb:3T12|rcsb pdb:3T1R|rcsb pdb:3T1X|rcsb pdb:3T1Q|interpro:IPR004942(Dynein light chain-related)|rcsb pdb:3T1S|refseq:YP_144397.1|interpro:IPR037587|mint:MINT-8299565(identity) - comment:mint|comment:"Stoichiometry: 4.0" comment:mint|comment:"Stoichiometry: 4.0" comment:mint|figure legend:st1 st2 sf3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/16 2014/10/16 rogid:KhBKIAFrmcrSbj87wTsoBE0fDgY300852 rogid:KhBKIAFrmcrSbj87wTsoBE0fDgY300852 intact-crc:F4A6F7C9317122DE|rigid:eRzqn4j7wO1fXicpQcjWJIjq2FM false - - 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5SJ82 uniprotkb:Q5SJ82 intact:EBI-7080132|ensemblbacteria:BAD70955|intact:MINT-8299764 intact:EBI-7080132|ensemblbacteria:BAD70955|intact:MINT-8299764 psi-mi:q5sj82_thet8(display_long)|uniprotkb:TTHA1132(locus name) psi-mi:q5sj82_thet8(display_long)|uniprotkb:TTHA1132(locus name) psi-mi:"MI:0114"(x-ray crystallography) Miertzschke et al. (2011) doi:10.1038/emboj.2011.291|pubmed:21847100|imex:IM-16684|mint:MINT-8296294 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7080186|mint:MINT-8299545|imex:IM-16684-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011228461.1|ensemblbacteria:BAD70955(gene)|ensemblbacteria:BAD70955(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|rcsb pdb:3T1V|interpro:IPR027417|interpro:IPR006689(ARF/SAR superfamily)|rcsb pdb:3T1T|rcsb pdb:3T12|rcsb pdb:3T1O|refseq:YP_144398.1|rcsb pdb:3T1Q|mint:MINT-8299547(identity) refseq:WP_011228461.1|ensemblbacteria:BAD70955(gene)|ensemblbacteria:BAD70955(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|rcsb pdb:3T1V|interpro:IPR027417|interpro:IPR006689(ARF/SAR superfamily)|rcsb pdb:3T1T|rcsb pdb:3T12|rcsb pdb:3T1O|refseq:YP_144398.1|rcsb pdb:3T1Q|mint:MINT-8299547(identity) - comment:mint|comment:"Stoichiometry: 2.0" comment:mint|comment:"Stoichiometry: 2.0" comment:mint|figure legend:sf1 st1 st2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/16 2014/10/16 rogid:G2QmsiUZkR/iAPkZUqrwqbpjSRI300852 rogid:G2QmsiUZkR/iAPkZUqrwqbpjSRI300852 intact-crc:15925DD8E24511AD|rigid:huAHejHWJFfiU7mQWJvM3VVbeO8 false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5SJ82 uniprotkb:Q5SJ83 intact:EBI-7080132|ensemblbacteria:BAD70955|intact:MINT-8299764 intact:EBI-7080155|ensemblbacteria:BAD70954|intact:MINT-8299766 psi-mi:q5sj82_thet8(display_long)|uniprotkb:TTHA1132(locus name) psi-mi:q5sj83_thet8(display_long)|uniprotkb:TTHA1131(locus name) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Miertzschke et al. (2011) doi:10.1038/emboj.2011.291|pubmed:21847100|imex:IM-16684|mint:MINT-8296294 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7080216|mint:MINT-8299591|imex:IM-16684-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011228461.1|ensemblbacteria:BAD70955(gene)|ensemblbacteria:BAD70955(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|rcsb pdb:3T1V|interpro:IPR027417|interpro:IPR006689(ARF/SAR superfamily)|rcsb pdb:3T1T|rcsb pdb:3T12|rcsb pdb:3T1O|refseq:YP_144398.1|rcsb pdb:3T1Q|mint:MINT-8299593(identity) refseq:WP_011228460.1|ensemblbacteria:BAD70954(gene)|ensemblbacteria:BAD70954(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060090"(molecular adaptor activity)|rcsb pdb:3T12|rcsb pdb:3T1R|rcsb pdb:3T1X|rcsb pdb:3T1Q|interpro:IPR004942(Dynein light chain-related)|rcsb pdb:3T1S|refseq:YP_144397.1|interpro:IPR037587|mint:MINT-8299595(identity) - comment:mint|comment:"Stoichiometry: 1.2" comment:mint|comment:"Stoichiometry: 2.1" comment:mint|figure legend:f3b f5 f7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) temp interaction:3.0x10^-6(molar) 2011/12/16 2022/01/21 rogid:G2QmsiUZkR/iAPkZUqrwqbpjSRI300852 rogid:KhBKIAFrmcrSbj87wTsoBE0fDgY300852 intact-crc:21BC1A9CCA23CEAA|rigid:IOZx7lzs5TVo1dlDhxP5DLGWd+4 false - - 1 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5SJ82 uniprotkb:Q5SJ83 intact:EBI-7080132|ensemblbacteria:BAD70955|intact:MINT-8299764 intact:EBI-7080155|ensemblbacteria:BAD70954|intact:MINT-8299766 psi-mi:q5sj82_thet8(display_long)|uniprotkb:TTHA1132(locus name) psi-mi:q5sj83_thet8(display_long)|uniprotkb:TTHA1131(locus name) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Miertzschke et al. (2011) doi:10.1038/emboj.2011.291|pubmed:21847100|imex:IM-16684|mint:MINT-8296294 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7080247|mint:MINT-8299622|imex:IM-16684-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011228461.1|ensemblbacteria:BAD70955(gene)|ensemblbacteria:BAD70955(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|rcsb pdb:3T1V|interpro:IPR027417|interpro:IPR006689(ARF/SAR superfamily)|rcsb pdb:3T1T|rcsb pdb:3T12|rcsb pdb:3T1O|refseq:YP_144398.1|rcsb pdb:3T1Q|mint:MINT-8299625(identity) refseq:WP_011228460.1|ensemblbacteria:BAD70954(gene)|ensemblbacteria:BAD70954(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060090"(molecular adaptor activity)|rcsb pdb:3T12|rcsb pdb:3T1R|rcsb pdb:3T1X|rcsb pdb:3T1Q|interpro:IPR004942(Dynein light chain-related)|rcsb pdb:3T1S|refseq:YP_144397.1|interpro:IPR037587|mint:MINT-8299627(identity) - comment:mint|comment:"Stoichiometry: 1.2" comment:mint|comment:"Stoichiometry: 2.1" comment:mint|figure legend:f3b f5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) temp interaction:35.0x10^-6(molar) 2011/12/16 2022/01/21 rogid:G2QmsiUZkR/iAPkZUqrwqbpjSRI300852 rogid:KhBKIAFrmcrSbj87wTsoBE0fDgY300852 intact-crc:1EAF136E98C03407|rigid:IOZx7lzs5TVo1dlDhxP5DLGWd+4 false - mutation decreasing interaction:72-72(MINT-8299635)|mutation decreasing interaction:68-68(MINT-8299632) 1 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5SJ82 uniprotkb:Q5SJ83 intact:EBI-7080132|ensemblbacteria:BAD70955|intact:MINT-8299764 intact:EBI-7080155|ensemblbacteria:BAD70954|intact:MINT-8299766 psi-mi:q5sj82_thet8(display_long)|uniprotkb:TTHA1132(locus name) psi-mi:q5sj83_thet8(display_long)|uniprotkb:TTHA1131(locus name) psi-mi:"MI:0071"(molecular sieving) Miertzschke et al. (2011) doi:10.1038/emboj.2011.291|pubmed:21847100|imex:IM-16684|mint:MINT-8296294 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7080281|mint:MINT-8299603|imex:IM-16684-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011228461.1|ensemblbacteria:BAD70955(gene)|ensemblbacteria:BAD70955(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|rcsb pdb:3T1V|interpro:IPR027417|interpro:IPR006689(ARF/SAR superfamily)|rcsb pdb:3T1T|rcsb pdb:3T12|rcsb pdb:3T1O|refseq:YP_144398.1|rcsb pdb:3T1Q|mint:MINT-8299605(identity) refseq:WP_011228460.1|ensemblbacteria:BAD70954(gene)|ensemblbacteria:BAD70954(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060090"(molecular adaptor activity)|rcsb pdb:3T12|rcsb pdb:3T1R|rcsb pdb:3T1X|rcsb pdb:3T1Q|interpro:IPR004942(Dynein light chain-related)|rcsb pdb:3T1S|refseq:YP_144397.1|interpro:IPR037587|mint:MINT-8299607(identity) - comment:mint|comment:"Stoichiometry: 1.2" comment:mint|comment:"Stoichiometry: 2.1" comment:mint|figure legend:f3c f3d sf2c sf5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/16 2022/01/21 rogid:G2QmsiUZkR/iAPkZUqrwqbpjSRI300852 rogid:KhBKIAFrmcrSbj87wTsoBE0fDgY300852 intact-crc:602C543DA0F4E957|rigid:IOZx7lzs5TVo1dlDhxP5DLGWd+4 false - mutation decreasing interaction:68-68(MINT-8299642)|mutation decreasing interaction:72-72(MINT-8299644) 1 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)