#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P08152 uniprotkb:P63280 intact:EBI-7070449|ensembl:ENSMUSP00000041053|intact:MINT-2828823 intact:EBI-80180|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q6RUT3|uniprotkb:Q86VB3|ensembl:ENSMUSP00000055714|ensembl:ENSMUSP00000134169|ensembl:ENSMUSP00000134261|ensembl:ENSMUSP00000134350|ensembl:ENSMUSP00000134450|ensembl:ENSMUSP00000134491 psi-mi:egr2_mouse(display_long)|uniprotkb:Egr2(gene name)|psi-mi:Egr2(display_short)|uniprotkb:Egr-2(gene name synonym)|uniprotkb:Krox-20(gene name synonym)|uniprotkb:Zfp-25(gene name synonym)|uniprotkb:Zinc finger protein Krox-20(gene name synonym)|uniprotkb:Early growth response protein 2(gene name synonym)|uniprotkb:E3 SUMO-protein transferase ERG2(gene name synonym) psi-mi:ubc9_mouse(display_long)|uniprotkb:Ube2i(gene name)|psi-mi:Ube2i(display_short)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:Ubce9(gene name synonym)|uniprotkb:Ubce2i(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:"MI:0018"(two hybrid) García-Gutiérrez et al. (2011) doi:10.1038/embor.2011.152|pubmed:21836637|imex:IM-16504|mint:MINT-8298166 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7070497|mint:MINT-8298184|imex:IM-16504-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001334387.1|refseq:XP_011241670.1|refseq:XP_006513272.1|refseq:XP_006513273.1|refseq:XP_006513274.1|refseq:XP_006513276.1|ensembl:ENSMUSG00000037868(gene)|ensembl:ENSMUST00000048289(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007611"(learning or memory)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010467"(gene expression)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021659"(rhombomere 3 structural organization)|go:"GO:0021660"(rhombomere 3 formation)|go:"GO:0021665"(rhombomere 5 structural organization)|go:"GO:0021666"(rhombomere 5 formation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032868"(response to insulin)|go:"GO:0035284"(brain segmentation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR021849|interpro:IPR036236|mint:P08152|reactome:R-MMU-9031628|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042552"(myelination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:NP_034248.2|mint:MINT-8298187(identity) refseq:NP_001171080.1|refseq:NP_001171081.1|refseq:NP_035795.1|ensembl:ENSMUSG00000015120(gene)|ensembl:ENSMUST00000049911(transcript)|ensembl:ENSMUST00000172618(transcript)|ensembl:ENSMUST00000173084(transcript)|ensembl:ENSMUST00000173713(transcript)|ensembl:ENSMUST00000174001(transcript)|ensembl:ENSMUST00000174031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990234"(transferase complex)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63280|rcsb pdb:1U9A|rcsb pdb:1U9B|rcsb pdb:2UYZ|rcsb pdb:2VRR|reactome:R-MMU-196791|reactome:R-MMU-3065678|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-4655427|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-8866904|reactome:R-MMU-9615933|refseq:XP_006524111.1|refseq:XP_006524112.1|dip:DIP-29276N|mint:MINT-8298186(identity) - comment:mint|comment:homomint|function:Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes - comment:homomint|figure legend:f1a f1c|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/12/13 2014/10/16 rogid:iKWeovUpB1gUsXGstJX/kSanYy410090 rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo10090 intact-crc:1C8A895A547B5BCA|rigid:X51ZuL5Z7Va3WPMQ0Nnwo4GSAxs false binding-associated region:329-425(MINT-8298206)|fusion protein:?-?(MINT-8298203) fusion protein:?-?(MINT-8298214) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08152 uniprotkb:Q61127 intact:EBI-7070449|ensembl:ENSMUSP00000041053|intact:MINT-2828823 intact:EBI-2366420|uniprotkb:Q80VR9|ensembl:ENSMUSP00000026469 psi-mi:egr2_mouse(display_long)|uniprotkb:Egr2(gene name)|psi-mi:Egr2(display_short)|uniprotkb:Egr-2(gene name synonym)|uniprotkb:Krox-20(gene name synonym)|uniprotkb:Zfp-25(gene name synonym)|uniprotkb:Zinc finger protein Krox-20(gene name synonym)|uniprotkb:Early growth response protein 2(gene name synonym)|uniprotkb:E3 SUMO-protein transferase ERG2(gene name synonym) psi-mi:nab2_mouse(display_long)|uniprotkb:Nab2(gene name)|psi-mi:Nab2(display_short)|uniprotkb:EGR-1-binding protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) García-Gutiérrez et al. (2011) doi:10.1038/embor.2011.152|pubmed:21836637|imex:IM-16504|mint:MINT-8298166 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7070609|mint:MINT-8298266|imex:IM-16504-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001334387.1|refseq:XP_011241670.1|refseq:XP_006513272.1|refseq:XP_006513273.1|refseq:XP_006513274.1|refseq:XP_006513276.1|ensembl:ENSMUSG00000037868(gene)|ensembl:ENSMUST00000048289(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007611"(learning or memory)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010467"(gene expression)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021659"(rhombomere 3 structural organization)|go:"GO:0021660"(rhombomere 3 formation)|go:"GO:0021665"(rhombomere 5 structural organization)|go:"GO:0021666"(rhombomere 5 formation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032868"(response to insulin)|go:"GO:0035284"(brain segmentation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR021849|interpro:IPR036236|mint:P08152|reactome:R-MMU-9031628|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042552"(myelination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:NP_034248.2|mint:MINT-8298269(identity) refseq:NP_001116367.1|refseq:NP_032694.2|ensembl:ENSMUSG00000025402(gene)|ensembl:ENSMUST00000026469(transcript)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR006989(Nab, central region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038398|interpro:IPR039040|mint:Q61127|reactome:R-MMU-9031628|mint:MINT-8298268(identity) - comment:mint|comment:homomint|function:Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes - figure legend:sf2b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/12/13 2014/10/16 rogid:iKWeovUpB1gUsXGstJX/kSanYy410090 rogid:rf3ukqRbH6FRLzgfVxvpwEl9Kvc10090 intact-crc:6F212CCA3FE7D3FF|rigid:5EvDg6yYsivmmNz9PYPx9VPrWj4 false fusion protein:?-?(MINT-8298271) fusion protein:?-?(MINT-8298275) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08152 uniprotkb:P63280 intact:EBI-7070449|ensembl:ENSMUSP00000041053|intact:MINT-2828823 intact:EBI-80180|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q6RUT3|uniprotkb:Q86VB3|ensembl:ENSMUSP00000055714|ensembl:ENSMUSP00000134169|ensembl:ENSMUSP00000134261|ensembl:ENSMUSP00000134350|ensembl:ENSMUSP00000134450|ensembl:ENSMUSP00000134491 psi-mi:egr2_mouse(display_long)|uniprotkb:Egr2(gene name)|psi-mi:Egr2(display_short)|uniprotkb:Egr-2(gene name synonym)|uniprotkb:Krox-20(gene name synonym)|uniprotkb:Zfp-25(gene name synonym)|uniprotkb:Zinc finger protein Krox-20(gene name synonym)|uniprotkb:Early growth response protein 2(gene name synonym)|uniprotkb:E3 SUMO-protein transferase ERG2(gene name synonym) psi-mi:ubc9_mouse(display_long)|uniprotkb:Ube2i(gene name)|psi-mi:Ube2i(display_short)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:Ubce9(gene name synonym)|uniprotkb:Ubce2i(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:"MI:0096"(pull down) García-Gutiérrez et al. (2011) doi:10.1038/embor.2011.152|pubmed:21836637|imex:IM-16504|mint:MINT-8298166 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7070678|mint:MINT-8298226|imex:IM-16504-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001334387.1|refseq:XP_011241670.1|refseq:XP_006513272.1|refseq:XP_006513273.1|refseq:XP_006513274.1|refseq:XP_006513276.1|ensembl:ENSMUSG00000037868(gene)|ensembl:ENSMUST00000048289(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007611"(learning or memory)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010467"(gene expression)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021659"(rhombomere 3 structural organization)|go:"GO:0021660"(rhombomere 3 formation)|go:"GO:0021665"(rhombomere 5 structural organization)|go:"GO:0021666"(rhombomere 5 formation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032868"(response to insulin)|go:"GO:0035284"(brain segmentation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR021849|interpro:IPR036236|mint:P08152|reactome:R-MMU-9031628|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042552"(myelination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:NP_034248.2|mint:MINT-8298228(identity) refseq:NP_001171080.1|refseq:NP_001171081.1|refseq:NP_035795.1|ensembl:ENSMUSG00000015120(gene)|ensembl:ENSMUST00000049911(transcript)|ensembl:ENSMUST00000172618(transcript)|ensembl:ENSMUST00000173084(transcript)|ensembl:ENSMUST00000173713(transcript)|ensembl:ENSMUST00000174001(transcript)|ensembl:ENSMUST00000174031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990234"(transferase complex)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63280|rcsb pdb:1U9A|rcsb pdb:1U9B|rcsb pdb:2UYZ|rcsb pdb:2VRR|reactome:R-MMU-196791|reactome:R-MMU-3065678|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-4655427|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-8866904|reactome:R-MMU-9615933|refseq:XP_006524111.1|refseq:XP_006524112.1|dip:DIP-29276N|mint:MINT-8298229(identity) - comment:mint|comment:homomint|function:Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes - figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/13 2014/10/16 rogid:iKWeovUpB1gUsXGstJX/kSanYy410090 rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo10090 intact-crc:C356E81A41721739|rigid:X51ZuL5Z7Va3WPMQ0Nnwo4GSAxs false - glutathione s tranferase tag:?-?(MINT-8298231) - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61127 uniprotkb:P11161 intact:EBI-2366420|uniprotkb:Q80VR9|ensembl:ENSMUSP00000026469 intact:EBI-625282|uniprotkb:Q68CZ5|uniprotkb:Q8IV26|uniprotkb:Q9UNA6|uniprotkb:B3KRD7|uniprotkb:B2R724|ensembl:ENSP00000242480 psi-mi:nab2_mouse(display_long)|uniprotkb:Nab2(gene name)|psi-mi:Nab2(display_short)|uniprotkb:EGR-1-binding protein 2(gene name synonym) psi-mi:egr2_human(display_long)|uniprotkb:Zinc finger protein Krox-20(gene name synonym)|uniprotkb:AT591(gene name synonym)|uniprotkb:EGR2(gene name)|psi-mi:EGR2(display_short)|uniprotkb:KROX20(gene name synonym)|uniprotkb:E3 SUMO-protein transferase ERG2(gene name synonym)|uniprotkb:Early growth response protein 2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) García-Gutiérrez et al. (2011) doi:10.1038/embor.2011.152|pubmed:21836637|imex:IM-16504|mint:MINT-8298166 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7070760|mint:MINT-8298254|imex:IM-16504-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116367.1|refseq:NP_032694.2|ensembl:ENSMUSG00000025402(gene)|ensembl:ENSMUST00000026469(transcript)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR006989(Nab, central region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038398|interpro:IPR039040|mint:Q61127|reactome:R-MMU-9031628|mint:MINT-8298257(identity) refseq:NP_001307966.1|refseq:NP_000390.2|refseq:NP_001129651.1|refseq:NP_001129649.1|refseq:NP_001129650.1|ensembl:ENSP00000242480|ensembl:ENST00000411732|ensembl:ENSP00000387634|ensembl:ENSG00000122877(gene)|ensembl:ENST00000242480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010467"(gene expression)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021659"(rhombomere 3 structural organization)|go:"GO:0021660"(rhombomere 3 formation)|go:"GO:0021665"(rhombomere 5 structural organization)|go:"GO:0021666"(rhombomere 5 formation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032868"(response to insulin)|go:"GO:0035284"(brain segmentation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042552"(myelination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR021849|interpro:IPR036236|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-9031628|reactome:R-HSA-9619665|mint:MINT-8298256(identity) go:"GO:0005634"(nucleus) - - figure legend:sf2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/12/13 2014/10/16 rogid:rf3ukqRbH6FRLzgfVxvpwEl9Kvc10090 rogid:J2XtPrvkDyR6kAQRiWzY2AUL0+49606 intact-crc:52BF7928CCFB7403|rigid:DJ8Q4rb+xgCTHRKAuLaIUQLqvhU false flag tag:?-?(MINT-8298262) - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q6PDQ2 uniprotkb:Q61127 intact:EBI-3043852|ensembl:ENSMUSP00000060054 intact:EBI-2366420|uniprotkb:Q80VR9|ensembl:ENSMUSP00000026469 psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:nab2_mouse(display_long)|uniprotkb:Nab2(gene name)|psi-mi:Nab2(display_short)|uniprotkb:EGR-1-binding protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) García-Gutiérrez et al. (2011) doi:10.1038/embor.2011.152|pubmed:21836637|imex:IM-16504|mint:MINT-8298166 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7070851|mint:MINT-8298296|imex:IM-16504-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N|mint:MINT-8298299(identity) refseq:NP_001116367.1|refseq:NP_032694.2|ensembl:ENSMUSG00000025402(gene)|ensembl:ENSMUST00000026469(transcript)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR006989(Nab, central region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038398|interpro:IPR039040|mint:Q61127|reactome:R-MMU-9031628|mint:MINT-8298298(identity) - - - figure legend:sf1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/12/13 2014/10/16 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 rogid:rf3ukqRbH6FRLzgfVxvpwEl9Kvc10090 intact-crc:4F1D01BDF6002449|rigid:JHG8IBzP52TzCLOBQyPpOUm93CI false ha tag:?-?(MINT-8298305) flag tag:?-?(MINT-8298301) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)