#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P35235	uniprotkb:P28776	intact:EBI-397236|uniprotkb:Q3TQ84|uniprotkb:Q64509|uniprotkb:Q6PCL5|ensembl:ENSMUSP00000098333	intact:EBI-4410822|ensembl:ENSMUSP00000033956	psi-mi:ptn11_mouse(display_long)|uniprotkb:Ptpn11(gene name)|psi-mi:Ptpn11(display_short)|uniprotkb:Protein-tyrosine phosphatase SYP(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:i23o1_mouse(display_long)|uniprotkb:Ido1(gene name)|psi-mi:Ido1(display_short)|uniprotkb:Ido(gene name synonym)|uniprotkb:Indo(gene name synonym)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pallotta et al. (2011)	pubmed:21804557|imex:IM-17624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-4410858|imex:IM-17624-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001103462.1|refseq:NP_035332.1|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P35235|rcsb pdb:1AYA|rcsb pdb:1AYB|rcsb pdb:1AYC|rcsb pdb:1AYD|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|reactome:R-MMU-1059683|reactome:R-MMU-109704|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|reactome:R-MMU-110056|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|reactome:R-MMU-112411|reactome:R-MMU-114604|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|reactome:R-MMU-1257604|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-210990|reactome:R-MMU-210993|reactome:R-MMU-388841|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5654689|reactome:R-MMU-8854691|reactome:R-MMU-8865999|reactome:R-MMU-8934593|reactome:R-MMU-909733|reactome:R-MMU-912694|reactome:R-MMU-936964|reactome:R-MMU-9674555|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654700|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-6811558|reactome:R-MMU-8853659|ensembl:ENSMUSG00000043733(gene)|ensembl:ENSMUST00000100770(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046888"(negative regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|dip:DIP-29669N	refseq:NP_001280619.1|refseq:NP_032350.1|dip:DIP-48663N|ensembl:ENSMUSG00000031551(gene)|ensembl:ENSMUST00000033956(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002678"(positive regulation of chronic inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0033754"(indoleamine 2,3-dioxygenase activity)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0036269"(swimming behavior)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|reactome:R-MMU-71240	-	-	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2011/09/23	2020/01/07	rogid:KL26Wt9vwG525fZ5SfvLc71Wsng10090	rogid:j/YVytdSfen0fshqesDab1Te66Y10090	intact-crc:30FA5AE8116A9991|rigid:AebulAvfbViuD4JNikk3aT5rD6A	false	-	biotin tag:?-?|O4'-phospho-L-tyrosine:253-253|sufficient binding region:248-258	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P28776	uniprotkb:P35235	intact:EBI-4410822|ensembl:ENSMUSP00000033956	intact:EBI-397236|uniprotkb:Q3TQ84|uniprotkb:Q64509|uniprotkb:Q6PCL5|ensembl:ENSMUSP00000098333	psi-mi:i23o1_mouse(display_long)|uniprotkb:Ido1(gene name)|psi-mi:Ido1(display_short)|uniprotkb:Ido(gene name synonym)|uniprotkb:Indo(gene name synonym)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)	psi-mi:ptn11_mouse(display_long)|uniprotkb:Ptpn11(gene name)|psi-mi:Ptpn11(display_short)|uniprotkb:Protein-tyrosine phosphatase SYP(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pallotta et al. (2011)	pubmed:21804557|imex:IM-17624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-4410820|imex:IM-17624-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001280619.1|refseq:NP_032350.1|dip:DIP-48663N|ensembl:ENSMUSG00000031551(gene)|ensembl:ENSMUST00000033956(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002678"(positive regulation of chronic inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0033754"(indoleamine 2,3-dioxygenase activity)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0036269"(swimming behavior)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|reactome:R-MMU-71240	refseq:NP_001103462.1|refseq:NP_035332.1|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P35235|rcsb pdb:1AYA|rcsb pdb:1AYB|rcsb pdb:1AYC|rcsb pdb:1AYD|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|reactome:R-MMU-1059683|reactome:R-MMU-109704|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|reactome:R-MMU-110056|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|reactome:R-MMU-112411|reactome:R-MMU-114604|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|reactome:R-MMU-1257604|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-210990|reactome:R-MMU-210993|reactome:R-MMU-388841|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5654689|reactome:R-MMU-8854691|reactome:R-MMU-8865999|reactome:R-MMU-8934593|reactome:R-MMU-909733|reactome:R-MMU-912694|reactome:R-MMU-936964|reactome:R-MMU-9674555|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654700|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-6811558|reactome:R-MMU-8853659|ensembl:ENSMUSG00000043733(gene)|ensembl:ENSMUST00000100770(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046888"(negative regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|dip:DIP-29669N	-	-	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2011/09/23	2020/01/07	rogid:j/YVytdSfen0fshqesDab1Te66Y10090	rogid:KL26Wt9vwG525fZ5SfvLc71Wsng10090	intact-crc:2B5AEBAF3AB768F1|rigid:0L6skzczWEEF9dMCMfYbmCWIu14	false	biotin tag:?-?|sufficient binding region:110-120|O4'-phospho-L-tyrosine:115-115	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P28776	uniprotkb:P29351	intact:EBI-4410822|ensembl:ENSMUSP00000033956	intact:EBI-2620699|uniprotkb:Q9QVA8|uniprotkb:Q9R0V6|uniprotkb:O35128|uniprotkb:Q63872|uniprotkb:Q63873|uniprotkb:Q63874|uniprotkb:Q921G3|uniprotkb:Q9QVA6|uniprotkb:Q9QVA7|ensembl:ENSMUSP00000108103	psi-mi:i23o1_mouse(display_long)|uniprotkb:Ido1(gene name)|psi-mi:Ido1(display_short)|uniprotkb:Ido(gene name synonym)|uniprotkb:Indo(gene name synonym)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)	psi-mi:ptn6_mouse(display_long)|uniprotkb:Ptpn6(gene name)|psi-mi:Ptpn6(display_short)|uniprotkb:Hcp(gene name synonym)|uniprotkb:Hcph(gene name synonym)|uniprotkb:Ptp1C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:70Z-SHP(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:PTPTY-42(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pallotta et al. (2011)	pubmed:21804557|imex:IM-17624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-4410820|imex:IM-17624-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001280619.1|refseq:NP_032350.1|dip:DIP-48663N|ensembl:ENSMUSG00000031551(gene)|ensembl:ENSMUST00000033956(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002678"(positive regulation of chronic inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0033754"(indoleamine 2,3-dioxygenase activity)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0036269"(swimming behavior)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|reactome:R-MMU-71240	refseq:NP_001071173.1|refseq:NP_038573.2|ensembl:ENSMUSG00000004266(gene)|ensembl:ENSMUST00000112484(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29351|reactome:R-MMU-114604|reactome:R-MMU-1433559|reactome:R-MMU-210990|reactome:R-MMU-388841|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5690714|reactome:R-MMU-6798695|reactome:R-MMU-877300|reactome:R-MMU-909733|reactome:R-MMU-912526|reactome:R-MMU-912694|reactome:R-MMU-983695|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|dip:DIP-41455N	-	-	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2011/09/23	2020/01/07	rogid:j/YVytdSfen0fshqesDab1Te66Y10090	rogid:7dtH2jT68TwvCkZu9rqVowIrEK010090	intact-crc:2B5AEBAF3AB768F1|rigid:0L6skzczWEEF9dMCMfYbmCWIu14	false	biotin tag:?-?|sufficient binding region:110-120|O4'-phospho-L-tyrosine:115-115	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P28776	uniprotkb:P35235	intact:EBI-4410822|ensembl:ENSMUSP00000033956	intact:EBI-397236|uniprotkb:Q3TQ84|uniprotkb:Q64509|uniprotkb:Q6PCL5|ensembl:ENSMUSP00000098333	psi-mi:i23o1_mouse(display_long)|uniprotkb:Ido1(gene name)|psi-mi:Ido1(display_short)|uniprotkb:Ido(gene name synonym)|uniprotkb:Indo(gene name synonym)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)	psi-mi:ptn11_mouse(display_long)|uniprotkb:Ptpn11(gene name)|psi-mi:Ptpn11(display_short)|uniprotkb:Protein-tyrosine phosphatase SYP(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pallotta et al. (2011)	pubmed:21804557|imex:IM-17624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-4410909|imex:IM-17624-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001280619.1|refseq:NP_032350.1|dip:DIP-48663N|ensembl:ENSMUSG00000031551(gene)|ensembl:ENSMUST00000033956(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002678"(positive regulation of chronic inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0033754"(indoleamine 2,3-dioxygenase activity)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0036269"(swimming behavior)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|reactome:R-MMU-71240	refseq:NP_001103462.1|refseq:NP_035332.1|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P35235|rcsb pdb:1AYA|rcsb pdb:1AYB|rcsb pdb:1AYC|rcsb pdb:1AYD|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|reactome:R-MMU-1059683|reactome:R-MMU-109704|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|reactome:R-MMU-110056|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|reactome:R-MMU-112411|reactome:R-MMU-114604|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|reactome:R-MMU-1257604|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-210990|reactome:R-MMU-210993|reactome:R-MMU-388841|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5654689|reactome:R-MMU-8854691|reactome:R-MMU-8865999|reactome:R-MMU-8934593|reactome:R-MMU-909733|reactome:R-MMU-912694|reactome:R-MMU-936964|reactome:R-MMU-9674555|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654700|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-6811558|reactome:R-MMU-8853659|ensembl:ENSMUSG00000043733(gene)|ensembl:ENSMUST00000100770(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046888"(negative regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|dip:DIP-29669N	-	-	-	figure legend:Fig. 3C|agonist:TGF-beta|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-pdc)|taxid:10090(Mouse-Plasmacytoid Dendritic Cells)	-	2011/09/23	2020/01/07	rogid:j/YVytdSfen0fshqesDab1Te66Y10090	rogid:KL26Wt9vwG525fZ5SfvLc71Wsng10090	intact-crc:F43E497733A300EC|rigid:0L6skzczWEEF9dMCMfYbmCWIu14	false	O4'-phospho-L-tyrosine:253-253|sufficient binding region:248-258|biotin tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P28776	uniprotkb:P29351	intact:EBI-4410822|ensembl:ENSMUSP00000033956	intact:EBI-2620699|uniprotkb:Q9QVA8|uniprotkb:Q9R0V6|uniprotkb:O35128|uniprotkb:Q63872|uniprotkb:Q63873|uniprotkb:Q63874|uniprotkb:Q921G3|uniprotkb:Q9QVA6|uniprotkb:Q9QVA7|ensembl:ENSMUSP00000108103	psi-mi:i23o1_mouse(display_long)|uniprotkb:Ido1(gene name)|psi-mi:Ido1(display_short)|uniprotkb:Ido(gene name synonym)|uniprotkb:Indo(gene name synonym)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)	psi-mi:ptn6_mouse(display_long)|uniprotkb:Ptpn6(gene name)|psi-mi:Ptpn6(display_short)|uniprotkb:Hcp(gene name synonym)|uniprotkb:Hcph(gene name synonym)|uniprotkb:Ptp1C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:70Z-SHP(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:PTPTY-42(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pallotta et al. (2011)	pubmed:21804557|imex:IM-17624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-4410909|imex:IM-17624-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001280619.1|refseq:NP_032350.1|dip:DIP-48663N|ensembl:ENSMUSG00000031551(gene)|ensembl:ENSMUST00000033956(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002678"(positive regulation of chronic inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0033754"(indoleamine 2,3-dioxygenase activity)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0036269"(swimming behavior)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|reactome:R-MMU-71240	refseq:NP_001071173.1|refseq:NP_038573.2|ensembl:ENSMUSG00000004266(gene)|ensembl:ENSMUST00000112484(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29351|reactome:R-MMU-114604|reactome:R-MMU-1433559|reactome:R-MMU-210990|reactome:R-MMU-388841|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5690714|reactome:R-MMU-6798695|reactome:R-MMU-877300|reactome:R-MMU-909733|reactome:R-MMU-912526|reactome:R-MMU-912694|reactome:R-MMU-983695|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|dip:DIP-41455N	-	-	-	figure legend:Fig. 3C|agonist:TGF-beta|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-pdc)|taxid:10090(Mouse-Plasmacytoid Dendritic Cells)	-	2011/09/23	2020/01/07	rogid:j/YVytdSfen0fshqesDab1Te66Y10090	rogid:7dtH2jT68TwvCkZu9rqVowIrEK010090	intact-crc:F43E497733A300EC|rigid:0L6skzczWEEF9dMCMfYbmCWIu14	false	O4'-phospho-L-tyrosine:253-253|sufficient binding region:248-258|biotin tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P28776	uniprotkb:P35235	intact:EBI-4410822|ensembl:ENSMUSP00000033956	intact:EBI-397236|uniprotkb:Q3TQ84|uniprotkb:Q64509|uniprotkb:Q6PCL5|ensembl:ENSMUSP00000098333	psi-mi:i23o1_mouse(display_long)|uniprotkb:Ido1(gene name)|psi-mi:Ido1(display_short)|uniprotkb:Ido(gene name synonym)|uniprotkb:Indo(gene name synonym)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)	psi-mi:ptn11_mouse(display_long)|uniprotkb:Ptpn11(gene name)|psi-mi:Ptpn11(display_short)|uniprotkb:Protein-tyrosine phosphatase SYP(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pallotta et al. (2011)	pubmed:21804557|imex:IM-17624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-4410931|imex:IM-17624-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001280619.1|refseq:NP_032350.1|dip:DIP-48663N|ensembl:ENSMUSG00000031551(gene)|ensembl:ENSMUST00000033956(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002678"(positive regulation of chronic inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0033754"(indoleamine 2,3-dioxygenase activity)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0036269"(swimming behavior)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|reactome:R-MMU-71240	refseq:NP_001103462.1|refseq:NP_035332.1|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P35235|rcsb pdb:1AYA|rcsb pdb:1AYB|rcsb pdb:1AYC|rcsb pdb:1AYD|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|reactome:R-MMU-1059683|reactome:R-MMU-109704|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|reactome:R-MMU-110056|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|reactome:R-MMU-112411|reactome:R-MMU-114604|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|reactome:R-MMU-1257604|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-210990|reactome:R-MMU-210993|reactome:R-MMU-388841|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5654689|reactome:R-MMU-8854691|reactome:R-MMU-8865999|reactome:R-MMU-8934593|reactome:R-MMU-909733|reactome:R-MMU-912694|reactome:R-MMU-936964|reactome:R-MMU-9674555|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654700|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-6811558|reactome:R-MMU-8853659|ensembl:ENSMUSG00000043733(gene)|ensembl:ENSMUST00000100770(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046888"(negative regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|dip:DIP-29669N	-	-	-	figure legend:Fig. 3C|agonist:TGF-beta|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-pdc)|taxid:10090(Mouse-Plasmacytoid Dendritic Cells)	-	2011/09/23	2020/01/07	rogid:j/YVytdSfen0fshqesDab1Te66Y10090	rogid:KL26Wt9vwG525fZ5SfvLc71Wsng10090	intact-crc:E00F4D6ADFED90B5|rigid:0L6skzczWEEF9dMCMfYbmCWIu14	false	biotin tag:?-?|sufficient binding region:110-120|O4'-phospho-L-tyrosine:115-115	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P28776	uniprotkb:P29351	intact:EBI-4410822|ensembl:ENSMUSP00000033956	intact:EBI-2620699|uniprotkb:Q9QVA8|uniprotkb:Q9R0V6|uniprotkb:O35128|uniprotkb:Q63872|uniprotkb:Q63873|uniprotkb:Q63874|uniprotkb:Q921G3|uniprotkb:Q9QVA6|uniprotkb:Q9QVA7|ensembl:ENSMUSP00000108103	psi-mi:i23o1_mouse(display_long)|uniprotkb:Ido1(gene name)|psi-mi:Ido1(display_short)|uniprotkb:Ido(gene name synonym)|uniprotkb:Indo(gene name synonym)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)	psi-mi:ptn6_mouse(display_long)|uniprotkb:Ptpn6(gene name)|psi-mi:Ptpn6(display_short)|uniprotkb:Hcp(gene name synonym)|uniprotkb:Hcph(gene name synonym)|uniprotkb:Ptp1C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:70Z-SHP(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:PTPTY-42(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pallotta et al. (2011)	pubmed:21804557|imex:IM-17624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-4410931|imex:IM-17624-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001280619.1|refseq:NP_032350.1|dip:DIP-48663N|ensembl:ENSMUSG00000031551(gene)|ensembl:ENSMUST00000033956(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002678"(positive regulation of chronic inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0033754"(indoleamine 2,3-dioxygenase activity)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0036269"(swimming behavior)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|reactome:R-MMU-71240	refseq:NP_001071173.1|refseq:NP_038573.2|ensembl:ENSMUSG00000004266(gene)|ensembl:ENSMUST00000112484(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29351|reactome:R-MMU-114604|reactome:R-MMU-1433559|reactome:R-MMU-210990|reactome:R-MMU-388841|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5690714|reactome:R-MMU-6798695|reactome:R-MMU-877300|reactome:R-MMU-909733|reactome:R-MMU-912526|reactome:R-MMU-912694|reactome:R-MMU-983695|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|dip:DIP-41455N	-	-	-	figure legend:Fig. 3C|agonist:TGF-beta|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-pdc)|taxid:10090(Mouse-Plasmacytoid Dendritic Cells)	-	2011/09/23	2020/01/07	rogid:j/YVytdSfen0fshqesDab1Te66Y10090	rogid:7dtH2jT68TwvCkZu9rqVowIrEK010090	intact-crc:E00F4D6ADFED90B5|rigid:0L6skzczWEEF9dMCMfYbmCWIu14	false	biotin tag:?-?|sufficient binding region:110-120|O4'-phospho-L-tyrosine:115-115	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P28776	uniprotkb:P29351	intact:EBI-4410822|ensembl:ENSMUSP00000033956	intact:EBI-2620699|uniprotkb:Q9QVA8|uniprotkb:Q9R0V6|uniprotkb:O35128|uniprotkb:Q63872|uniprotkb:Q63873|uniprotkb:Q63874|uniprotkb:Q921G3|uniprotkb:Q9QVA6|uniprotkb:Q9QVA7|ensembl:ENSMUSP00000108103	psi-mi:i23o1_mouse(display_long)|uniprotkb:Ido1(gene name)|psi-mi:Ido1(display_short)|uniprotkb:Ido(gene name synonym)|uniprotkb:Indo(gene name synonym)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)	psi-mi:ptn6_mouse(display_long)|uniprotkb:Ptpn6(gene name)|psi-mi:Ptpn6(display_short)|uniprotkb:Hcp(gene name synonym)|uniprotkb:Hcph(gene name synonym)|uniprotkb:Ptp1C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:70Z-SHP(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:PTPTY-42(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Pallotta et al. (2011)	pubmed:21804557|imex:IM-17624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-4410955|imex:IM-17624-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001280619.1|refseq:NP_032350.1|dip:DIP-48663N|ensembl:ENSMUSG00000031551(gene)|ensembl:ENSMUST00000033956(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002678"(positive regulation of chronic inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0033754"(indoleamine 2,3-dioxygenase activity)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0036269"(swimming behavior)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|reactome:R-MMU-71240	refseq:NP_001071173.1|refseq:NP_038573.2|ensembl:ENSMUSG00000004266(gene)|ensembl:ENSMUST00000112484(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29351|reactome:R-MMU-114604|reactome:R-MMU-1433559|reactome:R-MMU-210990|reactome:R-MMU-388841|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5690714|reactome:R-MMU-6798695|reactome:R-MMU-877300|reactome:R-MMU-909733|reactome:R-MMU-912526|reactome:R-MMU-912694|reactome:R-MMU-983695|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|dip:DIP-41455N	-	-	-	figure legend:Fig. 3D|agonist:TGF-B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-pdc)|taxid:10090(Mouse-Plasmacytoid Dendritic Cells)	-	2011/09/23	2020/01/07	rogid:j/YVytdSfen0fshqesDab1Te66Y10090	rogid:7dtH2jT68TwvCkZu9rqVowIrEK010090	intact-crc:DE6983A12225C244|rigid:0L6skzczWEEF9dMCMfYbmCWIu14	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P28776	uniprotkb:P35235	intact:EBI-4410822|ensembl:ENSMUSP00000033956	intact:EBI-397236|uniprotkb:Q3TQ84|uniprotkb:Q64509|uniprotkb:Q6PCL5|ensembl:ENSMUSP00000098333	psi-mi:i23o1_mouse(display_long)|uniprotkb:Ido1(gene name)|psi-mi:Ido1(display_short)|uniprotkb:Ido(gene name synonym)|uniprotkb:Indo(gene name synonym)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)	psi-mi:ptn11_mouse(display_long)|uniprotkb:Ptpn11(gene name)|psi-mi:Ptpn11(display_short)|uniprotkb:Protein-tyrosine phosphatase SYP(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Pallotta et al. (2011)	pubmed:21804557|imex:IM-17624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-4410955|imex:IM-17624-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001280619.1|refseq:NP_032350.1|dip:DIP-48663N|ensembl:ENSMUSG00000031551(gene)|ensembl:ENSMUST00000033956(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002678"(positive regulation of chronic inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0033754"(indoleamine 2,3-dioxygenase activity)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0036269"(swimming behavior)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|reactome:R-MMU-71240	refseq:NP_001103462.1|refseq:NP_035332.1|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P35235|rcsb pdb:1AYA|rcsb pdb:1AYB|rcsb pdb:1AYC|rcsb pdb:1AYD|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|reactome:R-MMU-1059683|reactome:R-MMU-109704|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|reactome:R-MMU-110056|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|reactome:R-MMU-112411|reactome:R-MMU-114604|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|reactome:R-MMU-1257604|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-210990|reactome:R-MMU-210993|reactome:R-MMU-388841|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5654689|reactome:R-MMU-8854691|reactome:R-MMU-8865999|reactome:R-MMU-8934593|reactome:R-MMU-909733|reactome:R-MMU-912694|reactome:R-MMU-936964|reactome:R-MMU-9674555|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654700|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-6811558|reactome:R-MMU-8853659|ensembl:ENSMUSG00000043733(gene)|ensembl:ENSMUST00000100770(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046888"(negative regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|dip:DIP-29669N	-	-	-	figure legend:Fig. 3D|agonist:TGF-B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-pdc)|taxid:10090(Mouse-Plasmacytoid Dendritic Cells)	-	2011/09/23	2020/01/07	rogid:j/YVytdSfen0fshqesDab1Te66Y10090	rogid:KL26Wt9vwG525fZ5SfvLc71Wsng10090	intact-crc:DE6983A12225C244|rigid:0L6skzczWEEF9dMCMfYbmCWIu14	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29351	uniprotkb:P28776	intact:EBI-2620699|uniprotkb:Q9QVA8|uniprotkb:Q9R0V6|uniprotkb:O35128|uniprotkb:Q63872|uniprotkb:Q63873|uniprotkb:Q63874|uniprotkb:Q921G3|uniprotkb:Q9QVA6|uniprotkb:Q9QVA7|ensembl:ENSMUSP00000108103	intact:EBI-4410822|ensembl:ENSMUSP00000033956	psi-mi:ptn6_mouse(display_long)|uniprotkb:Ptpn6(gene name)|psi-mi:Ptpn6(display_short)|uniprotkb:Hcp(gene name synonym)|uniprotkb:Hcph(gene name synonym)|uniprotkb:Ptp1C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:70Z-SHP(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:PTPTY-42(gene name synonym)	psi-mi:i23o1_mouse(display_long)|uniprotkb:Ido1(gene name)|psi-mi:Ido1(display_short)|uniprotkb:Ido(gene name synonym)|uniprotkb:Indo(gene name synonym)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Pallotta et al. (2011)	pubmed:21804557|imex:IM-17624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-4410977|imex:IM-17624-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001071173.1|refseq:NP_038573.2|ensembl:ENSMUSG00000004266(gene)|ensembl:ENSMUST00000112484(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29351|reactome:R-MMU-114604|reactome:R-MMU-1433559|reactome:R-MMU-210990|reactome:R-MMU-388841|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5690714|reactome:R-MMU-6798695|reactome:R-MMU-877300|reactome:R-MMU-909733|reactome:R-MMU-912526|reactome:R-MMU-912694|reactome:R-MMU-983695|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|dip:DIP-41455N	refseq:NP_001280619.1|refseq:NP_032350.1|dip:DIP-48663N|ensembl:ENSMUSG00000031551(gene)|ensembl:ENSMUST00000033956(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002678"(positive regulation of chronic inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0033754"(indoleamine 2,3-dioxygenase activity)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0036269"(swimming behavior)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|reactome:R-MMU-71240	go:"GO:0005829"(cytosol)	-	-	figure legend:Fig. 3G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2011/09/23	2014/10/16	rogid:7dtH2jT68TwvCkZu9rqVowIrEK010090	rogid:j/YVytdSfen0fshqesDab1Te66Y10090	intact-crc:530DCD8993A22CF3|rigid:922N63dNkD80toXzRHuw/5PYEMY	false	-	mutation decreasing interaction:115-115,253-253	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)