#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P12620 uniprotkb:P48787 intact:EBI-1042018|uniprotkb:P12618|uniprotkb:P12619|uniprotkb:P12621 intact:EBI-299254|ensembl:ENSMUSP00000096458 psi-mi:tnnt3_chick(display_long)|uniprotkb:TNNT3(gene name)|psi-mi:TNNT3(display_short) psi-mi:tnni3_mouse(display_long)|uniprotkb:Tnni3(gene name)|psi-mi:Tnni3(display_short)|uniprotkb:Cardiac troponin I(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Zhang et al. (2011) pubmed:21777381|imex:IM-16758|mint:MINT-8189768|mint:fj-11-0228.r1|doi:10.1111/j.1742-4658.2011.08250 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7037333|mint:MINT-8189773|imex:IM-16758-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001978(Troponin)|rcsb pdb:1YTZ|rcsb pdb:1YV0|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Z5H|refseq:XP_015142056.1|refseq:XP_015142059.1|refseq:XP_015142062.1|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005861"(troponin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0030172"(troponin C binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0045214"(sarcomere organization)|interpro:IPR027707|interpro:IPR027708|interpro:IPR038077|mint:MINT-8189979(identity) ensembl:ENSMUSG00000035458(gene)|ensembl:ENSMUST00000098859(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001980"(regulation of systemic arterial blood pressure by ischemic conditions)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005861"(troponin complex)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030016"(myofibril)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR001978(Troponin)|go:"GO:0030017"(sarcomere)|go:"GO:0030172"(troponin C binding)|interpro:IPR021666|interpro:IPR038077|go:"GO:0031014"(troponin T binding)|mint:P48787|rcsb pdb:2JPW|rcsb pdb:6KLT|rcsb pdb:6KLU|go:"GO:0032780"(negative regulation of ATP-dependent activity)|reactome:R-MMU-390522|go:"GO:0043292"(contractile fiber)|reactome:R-MMU-5578775|go:"GO:0046872"(metal ion binding)|refseq:NP_033432.1|mint:MINT-8189775(identity) - - - figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/28 2014/10/16 rogid:4E36cCGtkNXe81Xmfq9X4WoPXx09031 rogid:3woV/hrSVgUqPG+eAf3AHNXrQS810090 intact-crc:29F4D94392968B1F|rigid:HhUll8hUvkL0vHaaVrXZS8NQMek false - binding-associated region:29-211(MINT-8189778) - - psi-mi:"MI:0411"(enzyme linked immunosorbent assay) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13789 uniprotkb:P48787 intact:EBI-7037369|uniprotkb:P13790|intact:MINT-8189921 intact:EBI-299254|ensembl:ENSMUSP00000096458 psi-mi:tnnt2_bovin(display_long)|uniprotkb:TNNT2(gene name)|psi-mi:TNNT2(display_short)|uniprotkb:Cardiac muscle troponin T(gene name synonym) psi-mi:tnni3_mouse(display_long)|uniprotkb:Tnni3(gene name)|psi-mi:Tnni3(display_short)|uniprotkb:Cardiac troponin I(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Zhang et al. (2011) pubmed:21777381|imex:IM-16758|mint:MINT-8189768|mint:fj-11-0228.r1|doi:10.1111/j.1742-4658.2011.08250 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7037364|mint:MINT-8189781|imex:IM-16758-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005523"(tropomyosin binding)|go:"GO:0005861"(troponin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0030172"(troponin C binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR027707|interpro:IPR038077|interpro:IPR001978(Troponin)|mint:MINT-8189982(identity) ensembl:ENSMUSG00000035458(gene)|ensembl:ENSMUST00000098859(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001980"(regulation of systemic arterial blood pressure by ischemic conditions)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005861"(troponin complex)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030016"(myofibril)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR001978(Troponin)|go:"GO:0030017"(sarcomere)|go:"GO:0030172"(troponin C binding)|interpro:IPR021666|interpro:IPR038077|go:"GO:0031014"(troponin T binding)|mint:P48787|rcsb pdb:2JPW|rcsb pdb:6KLT|rcsb pdb:6KLU|go:"GO:0032780"(negative regulation of ATP-dependent activity)|reactome:R-MMU-390522|go:"GO:0043292"(contractile fiber)|reactome:R-MMU-5578775|go:"GO:0046872"(metal ion binding)|refseq:NP_033432.1|mint:MINT-8189783(identity) - comment:mint - figure legend:f3c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/28 2014/10/16 rogid:fgAnQCUg02x0oIzM+R6p+DRGocc9913 rogid:3woV/hrSVgUqPG+eAf3AHNXrQS810090 intact-crc:8E0C3DAF9DD32267|rigid:qXi3rr8UAcV4vDrVAIgZTVN1pPU false - binding-associated region:29-211(MINT-8189784) - - psi-mi:"MI:0411"(enzyme linked immunosorbent assay) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48787 uniprotkb:P50752 intact:EBI-299254|ensembl:ENSMUSP00000096458 intact:EBI-7037406|ensembl:ENSMUSP00000107717|intact:MINT-4138660|uniprotkb:Q64377|uniprotkb:Q64360 psi-mi:tnni3_mouse(display_long)|uniprotkb:Tnni3(gene name)|psi-mi:Tnni3(display_short)|uniprotkb:Cardiac troponin I(gene name synonym) psi-mi:tnnt2_mouse(display_long)|uniprotkb:Tnnt2(gene name)|psi-mi:Tnnt2(display_short)|uniprotkb:Cardiac muscle troponin T(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Zhang et al. (2011) pubmed:21777381|imex:IM-16758|mint:MINT-8189768|mint:fj-11-0228.r1|doi:10.1111/j.1742-4658.2011.08250 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7037442|mint:MINT-8190639|imex:IM-16758-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000035458(gene)|ensembl:ENSMUST00000098859(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001980"(regulation of systemic arterial blood pressure by ischemic conditions)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005861"(troponin complex)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030016"(myofibril)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR001978(Troponin)|go:"GO:0030017"(sarcomere)|go:"GO:0030172"(troponin C binding)|interpro:IPR021666|interpro:IPR038077|go:"GO:0031014"(troponin T binding)|mint:P48787|rcsb pdb:2JPW|rcsb pdb:6KLT|rcsb pdb:6KLU|go:"GO:0032780"(negative regulation of ATP-dependent activity)|reactome:R-MMU-390522|go:"GO:0043292"(contractile fiber)|reactome:R-MMU-5578775|go:"GO:0046872"(metal ion binding)|refseq:NP_033432.1|mint:MINT-8190641(identity) refseq:XP_006529456.1|refseq:XP_006529457.1|refseq:XP_006529458.1|ensembl:ENSMUSG00000026414(gene)|ensembl:ENSMUST00000112087(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005861"(troponin complex)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030172"(troponin C binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0031013"(troponin I binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032972"(regulation of muscle filament sliding speed)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR001978(Troponin)|interpro:IPR027707|interpro:IPR038077|mint:P50752|rcsb pdb:6KLT|rcsb pdb:6KLU|reactome:R-MMU-390522|refseq:NP_001123651.4|refseq:NP_001123652.1|refseq:NP_035749.1|refseq:NP_001123650.1|refseq:NP_001123648.1|refseq:NP_001123653.4|mint:MINT-8190642(identity) - - comment:mint|function:Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity figure legend:f5a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/28 2014/10/16 rogid:3woV/hrSVgUqPG+eAf3AHNXrQS810090 rogid:Qaf6kFbJOB+rcI/aukloHa9LSCE10090 intact-crc:FABE6DF1D3D89B81|rigid:bScuUAqokHMk/lAmT1Jv9H7KwnI false binding-associated region:29-192(MINT-8191063) binding-associated region:248-301(MINT-8191107) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48787 uniprotkb:Q5KR49 intact:EBI-299254|ensembl:ENSMUSP00000096458 intact:EBI-1221372|ensembl:ENSBTAP00000042255 psi-mi:tnni3_mouse(display_long)|uniprotkb:Tnni3(gene name)|psi-mi:Tnni3(display_short)|uniprotkb:Cardiac troponin I(gene name synonym) psi-mi:tpm1_bovin(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Zhang et al. (2011) pubmed:21777381|imex:IM-16758|mint:MINT-8189768|mint:fj-11-0228.r1|doi:10.1111/j.1742-4658.2011.08250 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7037442|mint:MINT-8190639|imex:IM-16758-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000035458(gene)|ensembl:ENSMUST00000098859(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001980"(regulation of systemic arterial blood pressure by ischemic conditions)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005861"(troponin complex)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030016"(myofibril)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR001978(Troponin)|go:"GO:0030017"(sarcomere)|go:"GO:0030172"(troponin C binding)|interpro:IPR021666|interpro:IPR038077|go:"GO:0031014"(troponin T binding)|mint:P48787|rcsb pdb:2JPW|rcsb pdb:6KLT|rcsb pdb:6KLU|go:"GO:0032780"(negative regulation of ATP-dependent activity)|reactome:R-MMU-390522|go:"GO:0043292"(contractile fiber)|reactome:R-MMU-5578775|go:"GO:0046872"(metal ion binding)|refseq:NP_033432.1|mint:MINT-8190641(identity) refseq:NP_001013608.1|ensembl:ENSBTAG00000005373(gene)|ensembl:ENSBTAT00000044796(transcript)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000533(Tropomyosin)|mint:MINT-8190643(identity) - - - figure legend:f5a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/28 2014/10/16 rogid:3woV/hrSVgUqPG+eAf3AHNXrQS810090 rogid:9/rJRuvRYf5qg6Mw0XmopWVtdHE9913 intact-crc:FABE6DF1D3D89B81|rigid:bScuUAqokHMk/lAmT1Jv9H7KwnI false binding-associated region:29-192(MINT-8191063) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) uniprotkb:P50752 uniprotkb:Q5KR49 intact:EBI-7037406|ensembl:ENSMUSP00000107717|intact:MINT-4138660|uniprotkb:Q64377|uniprotkb:Q64360 intact:EBI-1221372|ensembl:ENSBTAP00000042255 psi-mi:tnnt2_mouse(display_long)|uniprotkb:Tnnt2(gene name)|psi-mi:Tnnt2(display_short)|uniprotkb:Cardiac muscle troponin T(gene name synonym) psi-mi:tpm1_bovin(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Zhang et al. (2011) pubmed:21777381|imex:IM-16758|mint:MINT-8189768|mint:fj-11-0228.r1|doi:10.1111/j.1742-4658.2011.08250 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7037463|mint:MINT-8191176|imex:IM-16758-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006529456.1|refseq:XP_006529457.1|refseq:XP_006529458.1|ensembl:ENSMUSG00000026414(gene)|ensembl:ENSMUST00000112087(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005861"(troponin complex)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030172"(troponin C binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0031013"(troponin I binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032972"(regulation of muscle filament sliding speed)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR001978(Troponin)|interpro:IPR027707|interpro:IPR038077|mint:P50752|rcsb pdb:6KLT|rcsb pdb:6KLU|reactome:R-MMU-390522|refseq:NP_001123651.4|refseq:NP_001123652.1|refseq:NP_035749.1|refseq:NP_001123650.1|refseq:NP_001123648.1|refseq:NP_001123653.4|mint:MINT-8191178(identity) refseq:NP_001013608.1|ensembl:ENSBTAG00000005373(gene)|ensembl:ENSBTAT00000044796(transcript)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000533(Tropomyosin)|mint:MINT-8191179(identity) - comment:mint|function:Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity - figure legend:f5b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/28 2014/10/16 rogid:Qaf6kFbJOB+rcI/aukloHa9LSCE10090 rogid:9/rJRuvRYf5qg6Mw0XmopWVtdHE9913 intact-crc:9E440546E781F2F2|rigid:AxlXBtNeaTYkEZx4xlksqYOrI4c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0411"(enzyme linked immunosorbent assay)