#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P24456	uniprotkb:P50172	intact:EBI-4320946|uniprotkb:Q64490|ensembl:ENSMUSP00000072555	intact:EBI-4320920|ensembl:ENSMUSP00000016338|ensembl:ENSMUSP00000125620	psi-mi:cp2da_mouse(display_long)|uniprotkb:Cyp2d10(gene name)|psi-mi:Cyp2d10(display_short)|uniprotkb:Cyp2d-10(gene name synonym)|uniprotkb:CYPIID10(gene name synonym)|uniprotkb:Cytochrome P450-16-alpha(gene name synonym)|uniprotkb:Cytochrome P450CB(gene name synonym)|uniprotkb:Testosterone 16-alpha hydroxylase(gene name synonym)	psi-mi:dhi1_mouse(display_long)|uniprotkb:Hsd11b1(gene name)|psi-mi:Hsd11b1(display_short)|uniprotkb:Hsd11(gene name synonym)|uniprotkb:11-beta-hydroxysteroid dehydrogenase 1(gene name synonym)|uniprotkb:11beta-HSD1A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4324015|imex:IM-16547-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034135.2|ensembl:ENSMUSG00000094806(gene)|ensembl:ENSMUST00000072776(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR036396|mint:P24456|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008069(Cytochrome P450, E-class, group I, CYP2D-like)|interpro:IPR017972	refseq:NP_001038216.1|refseq:NP_032314.2|ensembl:ENSMUSG00000016194(gene)|ensembl:ENSMUST00000016338(transcript)|ensembl:ENSMUST00000161737(transcript)|go:"GO:0003845"("11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030324"(lung development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045177"(apical part of cell)|go:"GO:0050661"(NADP binding)|go:"GO:0070524"("11-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P50172|rcsb pdb:1Y5M|rcsb pdb:1Y5R|rcsb pdb:3GMD|rcsb pdb:4K26|rcsb pdb:4NMH|rcsb pdb:5PGZ|rcsb pdb:5QIJ|reactome:R-MMU-194002|go:"GO:0043231"(intracellular membrane-bounded organelle)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B-5|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:wLRneXE7gasseBnmpNLCypVQWPc10090	rogid:vciyVfWedFkHfdzWngUbBdRK/J010090	intact-crc:4DA54FDAB1E55EBF|rigid:DjgTI+bhhH8Kav2MuM6Tga2mKvE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P50172	uniprotkb:P97872	intact:EBI-4320920|ensembl:ENSMUSP00000016338|ensembl:ENSMUSP00000125620	intact:EBI-4320824|uniprotkb:Q8R1W6|ensembl:ENSMUSP00000029729|ensembl:ENSMUSP00000102664|ensembl:ENSMUSP00000102665	psi-mi:dhi1_mouse(display_long)|uniprotkb:Hsd11b1(gene name)|psi-mi:Hsd11b1(display_short)|uniprotkb:Hsd11(gene name synonym)|uniprotkb:11-beta-hydroxysteroid dehydrogenase 1(gene name synonym)|uniprotkb:11beta-HSD1A(gene name synonym)	psi-mi:fmo5_mouse(display_long)|uniprotkb:Fmo5(gene name)|psi-mi:Fmo5(display_short)|uniprotkb:Dimethylaniline oxidase 5(gene name synonym)|uniprotkb:Hepatic flavin-containing monooxygenase 5(gene name synonym)|uniprotkb:Dimethylaniline monooxygenase [N-oxide-forming] 5(gene name synonym)|uniprotkb:NAPDH oxidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4323965|imex:IM-16547-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001038216.1|refseq:NP_032314.2|ensembl:ENSMUSG00000016194(gene)|ensembl:ENSMUST00000016338(transcript)|ensembl:ENSMUST00000161737(transcript)|go:"GO:0003845"("11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030324"(lung development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045177"(apical part of cell)|go:"GO:0050661"(NADP binding)|go:"GO:0070524"("11-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P50172|rcsb pdb:1Y5M|rcsb pdb:1Y5R|rcsb pdb:3GMD|rcsb pdb:4K26|rcsb pdb:4NMH|rcsb pdb:5PGZ|rcsb pdb:5QIJ|reactome:R-MMU-194002|go:"GO:0043231"(intracellular membrane-bounded organelle)	refseq:NP_001155235.1|refseq:NP_001155237.1|refseq:NP_034362.2|refseq:XP_006501058.1|ensembl:ENSMUSG00000028088(gene)|ensembl:ENSMUST00000029729(transcript)|ensembl:ENSMUST00000107049(transcript)|ensembl:ENSMUST00000107050(transcript)|go:"GO:0004031"(aldehyde oxidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004499"(N,N-dimethylaniline monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017144"|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR002257("Flavin-containing monooxygenase (FMO) 5")|interpro:IPR020946|interpro:IPR036188|mint:P97872	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B-3|comment:PGRMC1  selectively coimmunoprecipitated in the M2-bound fraction compared with the M2-unbound fraction, whereas FMO5 and Cyp3a11 did not coimmunoprecipitate efficiently in the M2-bound fraction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:vciyVfWedFkHfdzWngUbBdRK/J010090	rogid:Z4EY0BHh+YUL6cKmVZgayGIouUA10090	intact-crc:F68F463C7C3942CA|rigid:ztJgaVef0k6f4PRzUGUUbnSuxNc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P50172	uniprotkb:O55022	intact:EBI-4320920|ensembl:ENSMUSP00000016338|ensembl:ENSMUSP00000125620	intact:EBI-770756|uniprotkb:Q99JN0|ensembl:ENSMUSP00000073061	psi-mi:dhi1_mouse(display_long)|uniprotkb:Hsd11b1(gene name)|psi-mi:Hsd11b1(display_short)|uniprotkb:Hsd11(gene name synonym)|uniprotkb:11-beta-hydroxysteroid dehydrogenase 1(gene name synonym)|uniprotkb:11beta-HSD1A(gene name synonym)	psi-mi:pgrc1_mouse(display_long)|uniprotkb:Pgrmc1(gene name)|psi-mi:Pgrmc1(display_short)|uniprotkb:Pgrmc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4323965|imex:IM-16547-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001038216.1|refseq:NP_032314.2|ensembl:ENSMUSG00000016194(gene)|ensembl:ENSMUST00000016338(transcript)|ensembl:ENSMUST00000161737(transcript)|go:"GO:0003845"("11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030324"(lung development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045177"(apical part of cell)|go:"GO:0050661"(NADP binding)|go:"GO:0070524"("11-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P50172|rcsb pdb:1Y5M|rcsb pdb:1Y5R|rcsb pdb:3GMD|rcsb pdb:4K26|rcsb pdb:4NMH|rcsb pdb:5PGZ|rcsb pdb:5QIJ|reactome:R-MMU-194002|go:"GO:0043231"(intracellular membrane-bounded organelle)	refseq:NP_058063.2|ensembl:ENSMUSG00000006373(gene)|ensembl:ENSMUST00000073339(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0007613"(memory)|go:"GO:0008306"(associative learning)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905809"(negative regulation of synapse organization)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O55022|reactome:R-MMU-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B-3|comment:PGRMC1  selectively coimmunoprecipitated in the M2-bound fraction compared with the M2-unbound fraction, whereas FMO5 and Cyp3a11 did not coimmunoprecipitate efficiently in the M2-bound fraction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:vciyVfWedFkHfdzWngUbBdRK/J010090	rogid:JJb2/xwky1pSXG+DPfq5+XVmbcw10090	intact-crc:F68F463C7C3942CA|rigid:ztJgaVef0k6f4PRzUGUUbnSuxNc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P50172	uniprotkb:P24456	intact:EBI-4320920|ensembl:ENSMUSP00000016338|ensembl:ENSMUSP00000125620	intact:EBI-4320946|uniprotkb:Q64490|ensembl:ENSMUSP00000072555	psi-mi:dhi1_mouse(display_long)|uniprotkb:Hsd11b1(gene name)|psi-mi:Hsd11b1(display_short)|uniprotkb:Hsd11(gene name synonym)|uniprotkb:11-beta-hydroxysteroid dehydrogenase 1(gene name synonym)|uniprotkb:11beta-HSD1A(gene name synonym)	psi-mi:cp2da_mouse(display_long)|uniprotkb:Cyp2d10(gene name)|psi-mi:Cyp2d10(display_short)|uniprotkb:Cyp2d-10(gene name synonym)|uniprotkb:CYPIID10(gene name synonym)|uniprotkb:Cytochrome P450-16-alpha(gene name synonym)|uniprotkb:Cytochrome P450CB(gene name synonym)|uniprotkb:Testosterone 16-alpha hydroxylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4323965|imex:IM-16547-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001038216.1|refseq:NP_032314.2|ensembl:ENSMUSG00000016194(gene)|ensembl:ENSMUST00000016338(transcript)|ensembl:ENSMUST00000161737(transcript)|go:"GO:0003845"("11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030324"(lung development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045177"(apical part of cell)|go:"GO:0050661"(NADP binding)|go:"GO:0070524"("11-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P50172|rcsb pdb:1Y5M|rcsb pdb:1Y5R|rcsb pdb:3GMD|rcsb pdb:4K26|rcsb pdb:4NMH|rcsb pdb:5PGZ|rcsb pdb:5QIJ|reactome:R-MMU-194002|go:"GO:0043231"(intracellular membrane-bounded organelle)	refseq:NP_034135.2|ensembl:ENSMUSG00000094806(gene)|ensembl:ENSMUST00000072776(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR036396|mint:P24456|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008069(Cytochrome P450, E-class, group I, CYP2D-like)|interpro:IPR017972	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B-3|comment:PGRMC1  selectively coimmunoprecipitated in the M2-bound fraction compared with the M2-unbound fraction, whereas FMO5 and Cyp3a11 did not coimmunoprecipitate efficiently in the M2-bound fraction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:vciyVfWedFkHfdzWngUbBdRK/J010090	rogid:wLRneXE7gasseBnmpNLCypVQWPc10090	intact-crc:F68F463C7C3942CA|rigid:ztJgaVef0k6f4PRzUGUUbnSuxNc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97872	uniprotkb:Q64459	intact:EBI-4320824|uniprotkb:Q8R1W6|ensembl:ENSMUSP00000029729|ensembl:ENSMUSP00000102664|ensembl:ENSMUSP00000102665	intact:EBI-4320900|ensembl:ENSMUSP00000037665	psi-mi:fmo5_mouse(display_long)|uniprotkb:Fmo5(gene name)|psi-mi:Fmo5(display_short)|uniprotkb:Dimethylaniline oxidase 5(gene name synonym)|uniprotkb:Hepatic flavin-containing monooxygenase 5(gene name synonym)|uniprotkb:Dimethylaniline monooxygenase [N-oxide-forming] 5(gene name synonym)|uniprotkb:NAPDH oxidase(gene name synonym)	psi-mi:cp3ab_mouse(display_long)|uniprotkb:Cyp3a11(gene name)|psi-mi:Cyp3a11(display_short)|uniprotkb:Cyp3a-11(gene name synonym)|uniprotkb:CYPIIIA11(gene name synonym)|uniprotkb:Cytochrome P-450IIIAM1(gene name synonym)|uniprotkb:Cytochrome P-450UT(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321608|imex:IM-16547-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001155235.1|refseq:NP_001155237.1|refseq:NP_034362.2|refseq:XP_006501058.1|ensembl:ENSMUSG00000028088(gene)|ensembl:ENSMUST00000029729(transcript)|ensembl:ENSMUST00000107049(transcript)|ensembl:ENSMUST00000107050(transcript)|go:"GO:0004031"(aldehyde oxidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004499"(N,N-dimethylaniline monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017144"|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR002257("Flavin-containing monooxygenase (FMO) 5")|interpro:IPR020946|interpro:IPR036188|mint:P97872	refseq:NP_031844.1|ensembl:ENSMUSG00000056035(gene)|ensembl:ENSMUST00000035918(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0008401"(retinoic acid 4-hydroxylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|go:"GO:0032451"(demethylase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0101020"(estrogen 16-alpha-hydroxylase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002402(Cytochrome P450, E-class, group II)|interpro:IPR008072(Cytochrome P450, E-class, CYP3A)|interpro:IPR017972|interpro:IPR036396|mint:Q64459|reactome:R-MMU-211981|reactome:R-MMU-5423646|reactome:R-MMU-9027307|go:"GO:0050649"(testosterone 6-beta-hydroxylase activity)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B|comment:The fraction of PGRMC1 and mEH coprecipitating from the M2-bound fractions was much greater than from the M2-unbound fraction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:Z4EY0BHh+YUL6cKmVZgayGIouUA10090	rogid:HzIYdf39IckB+AWc8HXa7nSAj6M10090	intact-crc:ED58CCA5D1FB2AA4|rigid:4VcRgFhQu6HDCTZ0hiUlYSZVo8A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97872	uniprotkb:P50172	intact:EBI-4320824|uniprotkb:Q8R1W6|ensembl:ENSMUSP00000029729|ensembl:ENSMUSP00000102664|ensembl:ENSMUSP00000102665	intact:EBI-4320920|ensembl:ENSMUSP00000016338|ensembl:ENSMUSP00000125620	psi-mi:fmo5_mouse(display_long)|uniprotkb:Fmo5(gene name)|psi-mi:Fmo5(display_short)|uniprotkb:Dimethylaniline oxidase 5(gene name synonym)|uniprotkb:Hepatic flavin-containing monooxygenase 5(gene name synonym)|uniprotkb:Dimethylaniline monooxygenase [N-oxide-forming] 5(gene name synonym)|uniprotkb:NAPDH oxidase(gene name synonym)	psi-mi:dhi1_mouse(display_long)|uniprotkb:Hsd11b1(gene name)|psi-mi:Hsd11b1(display_short)|uniprotkb:Hsd11(gene name synonym)|uniprotkb:11-beta-hydroxysteroid dehydrogenase 1(gene name synonym)|uniprotkb:11beta-HSD1A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321608|imex:IM-16547-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001155235.1|refseq:NP_001155237.1|refseq:NP_034362.2|refseq:XP_006501058.1|ensembl:ENSMUSG00000028088(gene)|ensembl:ENSMUST00000029729(transcript)|ensembl:ENSMUST00000107049(transcript)|ensembl:ENSMUST00000107050(transcript)|go:"GO:0004031"(aldehyde oxidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004499"(N,N-dimethylaniline monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017144"|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR002257("Flavin-containing monooxygenase (FMO) 5")|interpro:IPR020946|interpro:IPR036188|mint:P97872	refseq:NP_001038216.1|refseq:NP_032314.2|ensembl:ENSMUSG00000016194(gene)|ensembl:ENSMUST00000016338(transcript)|ensembl:ENSMUST00000161737(transcript)|go:"GO:0003845"("11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030324"(lung development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045177"(apical part of cell)|go:"GO:0050661"(NADP binding)|go:"GO:0070524"("11-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P50172|rcsb pdb:1Y5M|rcsb pdb:1Y5R|rcsb pdb:3GMD|rcsb pdb:4K26|rcsb pdb:4NMH|rcsb pdb:5PGZ|rcsb pdb:5QIJ|reactome:R-MMU-194002|go:"GO:0043231"(intracellular membrane-bounded organelle)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B|comment:The fraction of PGRMC1 and mEH coprecipitating from the M2-bound fractions was much greater than from the M2-unbound fraction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:Z4EY0BHh+YUL6cKmVZgayGIouUA10090	rogid:vciyVfWedFkHfdzWngUbBdRK/J010090	intact-crc:ED58CCA5D1FB2AA4|rigid:4VcRgFhQu6HDCTZ0hiUlYSZVo8A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97872	uniprotkb:Q9D379	intact:EBI-4320824|uniprotkb:Q8R1W6|ensembl:ENSMUSP00000029729|ensembl:ENSMUSP00000102664|ensembl:ENSMUSP00000102665	intact:EBI-4320880|uniprotkb:P97869|ensembl:ENSMUSP00000047551	psi-mi:fmo5_mouse(display_long)|uniprotkb:Fmo5(gene name)|psi-mi:Fmo5(display_short)|uniprotkb:Dimethylaniline oxidase 5(gene name synonym)|uniprotkb:Hepatic flavin-containing monooxygenase 5(gene name synonym)|uniprotkb:Dimethylaniline monooxygenase [N-oxide-forming] 5(gene name synonym)|uniprotkb:NAPDH oxidase(gene name synonym)	psi-mi:hyep_mouse(display_long)|uniprotkb:Ephx1(gene name)|psi-mi:Ephx1(display_short)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321608|imex:IM-16547-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001155235.1|refseq:NP_001155237.1|refseq:NP_034362.2|refseq:XP_006501058.1|ensembl:ENSMUSG00000028088(gene)|ensembl:ENSMUST00000029729(transcript)|ensembl:ENSMUST00000107049(transcript)|ensembl:ENSMUST00000107050(transcript)|go:"GO:0004031"(aldehyde oxidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004499"(N,N-dimethylaniline monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017144"|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR002257("Flavin-containing monooxygenase (FMO) 5")|interpro:IPR020946|interpro:IPR036188|mint:P97872	refseq:NP_034275.1|refseq:NP_001299847.1|ensembl:ENSMUSG00000038776(gene)|ensembl:ENSMUST00000036928(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0034312"(diol biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR010497(Epoxide hydrolase, N-terminal)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|mint:Q9D379|reactome:R-MMU-211945|go:"GO:0097176"(epoxide metabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B|comment:The fraction of PGRMC1 and mEH coprecipitating from the M2-bound fractions was much greater than from the M2-unbound fraction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:Z4EY0BHh+YUL6cKmVZgayGIouUA10090	rogid:Ha5pbdo0GK7HPNskQw6y0dJjgBg10090	intact-crc:ED58CCA5D1FB2AA4|rigid:4VcRgFhQu6HDCTZ0hiUlYSZVo8A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97872	uniprotkb:O55022	intact:EBI-4320824|uniprotkb:Q8R1W6|ensembl:ENSMUSP00000029729|ensembl:ENSMUSP00000102664|ensembl:ENSMUSP00000102665	intact:EBI-770756|uniprotkb:Q99JN0|ensembl:ENSMUSP00000073061	psi-mi:fmo5_mouse(display_long)|uniprotkb:Fmo5(gene name)|psi-mi:Fmo5(display_short)|uniprotkb:Dimethylaniline oxidase 5(gene name synonym)|uniprotkb:Hepatic flavin-containing monooxygenase 5(gene name synonym)|uniprotkb:Dimethylaniline monooxygenase [N-oxide-forming] 5(gene name synonym)|uniprotkb:NAPDH oxidase(gene name synonym)	psi-mi:pgrc1_mouse(display_long)|uniprotkb:Pgrmc1(gene name)|psi-mi:Pgrmc1(display_short)|uniprotkb:Pgrmc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321608|imex:IM-16547-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001155235.1|refseq:NP_001155237.1|refseq:NP_034362.2|refseq:XP_006501058.1|ensembl:ENSMUSG00000028088(gene)|ensembl:ENSMUST00000029729(transcript)|ensembl:ENSMUST00000107049(transcript)|ensembl:ENSMUST00000107050(transcript)|go:"GO:0004031"(aldehyde oxidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004499"(N,N-dimethylaniline monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017144"|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR002257("Flavin-containing monooxygenase (FMO) 5")|interpro:IPR020946|interpro:IPR036188|mint:P97872	refseq:NP_058063.2|ensembl:ENSMUSG00000006373(gene)|ensembl:ENSMUST00000073339(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0007613"(memory)|go:"GO:0008306"(associative learning)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905809"(negative regulation of synapse organization)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O55022|reactome:R-MMU-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B|comment:The fraction of PGRMC1 and mEH coprecipitating from the M2-bound fractions was much greater than from the M2-unbound fraction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:Z4EY0BHh+YUL6cKmVZgayGIouUA10090	rogid:JJb2/xwky1pSXG+DPfq5+XVmbcw10090	intact-crc:ED58CCA5D1FB2AA4|rigid:4VcRgFhQu6HDCTZ0hiUlYSZVo8A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9D379	uniprotkb:P24456	intact:EBI-4320880|uniprotkb:P97869|ensembl:ENSMUSP00000047551	intact:EBI-4320946|uniprotkb:Q64490|ensembl:ENSMUSP00000072555	psi-mi:hyep_mouse(display_long)|uniprotkb:Ephx1(gene name)|psi-mi:Ephx1(display_short)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	psi-mi:cp2da_mouse(display_long)|uniprotkb:Cyp2d10(gene name)|psi-mi:Cyp2d10(display_short)|uniprotkb:Cyp2d-10(gene name synonym)|uniprotkb:CYPIID10(gene name synonym)|uniprotkb:Cytochrome P450-16-alpha(gene name synonym)|uniprotkb:Cytochrome P450CB(gene name synonym)|uniprotkb:Testosterone 16-alpha hydroxylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4323990|imex:IM-16547-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034275.1|refseq:NP_001299847.1|ensembl:ENSMUSG00000038776(gene)|ensembl:ENSMUST00000036928(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0034312"(diol biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR010497(Epoxide hydrolase, N-terminal)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|mint:Q9D379|reactome:R-MMU-211945|go:"GO:0097176"(epoxide metabolic process)	refseq:NP_034135.2|ensembl:ENSMUSG00000094806(gene)|ensembl:ENSMUST00000072776(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR036396|mint:P24456|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008069(Cytochrome P450, E-class, group I, CYP2D-like)|interpro:IPR017972	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B-4|comment:mEH  coimmunoprecipitated in the M2-bound fraction with PGRMC1 and Cyp2d10, but not with Cyp3a11.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:Ha5pbdo0GK7HPNskQw6y0dJjgBg10090	rogid:wLRneXE7gasseBnmpNLCypVQWPc10090	intact-crc:968C88AF1405E6FE|rigid:hoqMpsIA79XB5cVtzjv9VGFX0so	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9D379	uniprotkb:O55022	intact:EBI-4320880|uniprotkb:P97869|ensembl:ENSMUSP00000047551	intact:EBI-770756|uniprotkb:Q99JN0|ensembl:ENSMUSP00000073061	psi-mi:hyep_mouse(display_long)|uniprotkb:Ephx1(gene name)|psi-mi:Ephx1(display_short)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	psi-mi:pgrc1_mouse(display_long)|uniprotkb:Pgrmc1(gene name)|psi-mi:Pgrmc1(display_short)|uniprotkb:Pgrmc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4323990|imex:IM-16547-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034275.1|refseq:NP_001299847.1|ensembl:ENSMUSG00000038776(gene)|ensembl:ENSMUST00000036928(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0034312"(diol biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR010497(Epoxide hydrolase, N-terminal)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|mint:Q9D379|reactome:R-MMU-211945|go:"GO:0097176"(epoxide metabolic process)	refseq:NP_058063.2|ensembl:ENSMUSG00000006373(gene)|ensembl:ENSMUST00000073339(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0007613"(memory)|go:"GO:0008306"(associative learning)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905809"(negative regulation of synapse organization)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O55022|reactome:R-MMU-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B-4|comment:mEH  coimmunoprecipitated in the M2-bound fraction with PGRMC1 and Cyp2d10, but not with Cyp3a11.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:Ha5pbdo0GK7HPNskQw6y0dJjgBg10090	rogid:JJb2/xwky1pSXG+DPfq5+XVmbcw10090	intact-crc:968C88AF1405E6FE|rigid:hoqMpsIA79XB5cVtzjv9VGFX0so	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41216	uniprotkb:O55022	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-770756|uniprotkb:Q99JN0|ensembl:ENSMUSP00000073061	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:pgrc1_mouse(display_long)|uniprotkb:Pgrmc1(gene name)|psi-mi:Pgrmc1(display_short)|uniprotkb:Pgrmc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4323939|imex:IM-16547-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	refseq:NP_058063.2|ensembl:ENSMUSG00000006373(gene)|ensembl:ENSMUST00000073339(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0007613"(memory)|go:"GO:0008306"(associative learning)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905809"(negative regulation of synapse organization)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O55022|reactome:R-MMU-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B-2|comment:Coimmunoprecipitation  with ACSL1 of PGRMC1 and mEH occurs, but not  with 11beta-HSD1 in the M2-bound fraction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:JJb2/xwky1pSXG+DPfq5+XVmbcw10090	intact-crc:198A15A19A9CD6E2|rigid:STITfhm0a1aX3bpJ/kWUDWpHDmg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41216	uniprotkb:Q9D379	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-4320880|uniprotkb:P97869|ensembl:ENSMUSP00000047551	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:hyep_mouse(display_long)|uniprotkb:Ephx1(gene name)|psi-mi:Ephx1(display_short)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4323939|imex:IM-16547-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	refseq:NP_034275.1|refseq:NP_001299847.1|ensembl:ENSMUSG00000038776(gene)|ensembl:ENSMUST00000036928(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0034312"(diol biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR010497(Epoxide hydrolase, N-terminal)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|mint:Q9D379|reactome:R-MMU-211945|go:"GO:0097176"(epoxide metabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 4B-2|comment:Coimmunoprecipitation  with ACSL1 of PGRMC1 and mEH occurs, but not  with 11beta-HSD1 in the M2-bound fraction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:Ha5pbdo0GK7HPNskQw6y0dJjgBg10090	intact-crc:198A15A19A9CD6E2|rigid:STITfhm0a1aX3bpJ/kWUDWpHDmg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:Q80XN0	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-773084|uniprotkb:Q3UL45|uniprotkb:Q3UJS9|uniprotkb:Q8BK53|uniprotkb:Q8R0C8|ensembl:ENSMUSP00000087192|ensembl:ENSMUSP00000110881|ensembl:ENSMUSP00000110882	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:bdh_mouse(display_long)|uniprotkb:3-hydroxybutyrate dehydrogenase(gene name synonym)|uniprotkb:Bdh1(gene name)|psi-mi:Bdh1(display_short)|uniprotkb:Bdh(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_001116155.1|refseq:NP_780386.3|ensembl:ENSMUSG00000046598(gene)|ensembl:ENSMUST00000089759(transcript)|ensembl:ENSMUST00000115226(transcript)|ensembl:ENSMUST00000115227(transcript)|go:"GO:0003858"(3-hydroxybutyrate dehydrogenase activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008152"(metabolic process)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q80XN0|reactome:R-MMU-77108|reactome:R-MMU-77111	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:E1f2/RUOR/OJHukOHXp5RolO7Kw10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:P19157	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-2309446|uniprotkb:Q8BNY4|ensembl:ENSMUSP00000129565	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:gstp1_mouse(display_long)|uniprotkb:Gstp1(gene name)|psi-mi:Gstp1(display_short)|uniprotkb:Gstpib(gene name synonym)|uniprotkb:GST YF-YF(gene name synonym)|uniprotkb:GST-piB(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:Preadipocyte growth factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_038569.1|ensembl:ENSMUSG00000060803(gene)|ensembl:ENSMUST00000169613(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:2000429"(negative regulation of neutrophil aggregation)|go:"GO:2000469"(negative regulation of peroxidase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|mint:P19157|rcsb pdb:1BAY|rcsb pdb:1GLP|rcsb pdb:1GLQ|rcsb pdb:1GSY|rcsb pdb:1GTI|rcsb pdb:2GLR|rcsb pdb:2OA7|rcsb pdb:2OAC|rcsb pdb:2OAD|rcsb pdb:3O76|reactome:R-MMU-156590|reactome:R-MMU-3299685|reactome:R-MMU-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:hJoMh/r+TgFJqQL95dBmcBsAVn810090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:Q8VCR2	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4321116|uniprotkb:A8Y5N6|uniprotkb:Q8CIU2|ensembl:ENSMUSP00000046772	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:dhb13_mouse(display_long)|uniprotkb:Hsd17b13(gene name)|psi-mi:Hsd17b13(display_short)|uniprotkb:Alcohol dehydrogenase PAN1B-like(gene name synonym)|uniprotkb:Scdr9(gene name synonym)|uniprotkb:Short-chain dehydrogenase/reductase 9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	uniprotkb:A8Y5N5(uniprot-removed-ac)|refseq:NP_001156958.1|refseq:NP_932147.2|ensembl:ENSMUSG00000034528(gene)|ensembl:ENSMUST00000048118(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0016229"(steroid dehydrogenase activity)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|reactome:R-MMU-8964572	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:EkCxd/wrSWEOEzw+PnSrlBZ3Sfc10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:P41216	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:P63017	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:Q9D379	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320880|uniprotkb:P97869|ensembl:ENSMUSP00000047551	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:hyep_mouse(display_long)|uniprotkb:Ephx1(gene name)|psi-mi:Ephx1(display_short)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_034275.1|refseq:NP_001299847.1|ensembl:ENSMUSG00000038776(gene)|ensembl:ENSMUST00000036928(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0034312"(diol biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR010497(Epoxide hydrolase, N-terminal)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|mint:Q9D379|reactome:R-MMU-211945|go:"GO:0097176"(epoxide metabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:Ha5pbdo0GK7HPNskQw6y0dJjgBg10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:Q811M6	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320815	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:q811m6_mouse(display_long)|uniprotkb:Igtp(gene name)|psi-mi:Igtp(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	interpro:IPR007743(Interferon-inducible GTPase)|interpro:IPR030385|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0035458"(cellular response to interferon-beta)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:IPjV5zlqpxOM+kCKnbZmzGiPk8Q10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:Q3UNW2	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320978	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:q3unw2_mouse(display_long)|uniprotkb:Cyp2d9(gene name)|psi-mi:Cyp2d9(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008069(Cytochrome P450, E-class, group I, CYP2D-like)|refseq:NP_034136.2|interpro:IPR036396|go:"GO:0005506"(iron ion binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:/uLVadRU7lGSdo9R75gslmMX83k10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:P20029	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:Q9ES97	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-643369|uniprotkb:Q3UF62|uniprotkb:Q544J1|uniprotkb:Q68FE4|uniprotkb:Q6IM69|uniprotkb:Q6R8K6|uniprotkb:Q6R8K7|uniprotkb:Q6T929|uniprotkb:Q8C6D5|uniprotkb:Q8CCU2|ensembl:ENSMUSP00000065810	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:rtn3_mouse(display_long)|uniprotkb:Rtn3(gene name)|psi-mi:Rtn3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_001003933.1|refseq:NP_001003934.1|refseq:NP_444306.1|refseq:NP_001258415.1|refseq:NP_001258416.1|ensembl:ENSMUSG00000024758(gene)|ensembl:ENSMUST00000065304(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045202"(synapse)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:Q9ES97|reactome:R-MMU-8849932	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:6FGasKiLqE0qkcxmPiyTcBrk2ek10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:O55022	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-770756|uniprotkb:Q99JN0|ensembl:ENSMUSP00000073061	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:pgrc1_mouse(display_long)|uniprotkb:Pgrmc1(gene name)|psi-mi:Pgrmc1(display_short)|uniprotkb:Pgrmc(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_058063.2|ensembl:ENSMUSG00000006373(gene)|ensembl:ENSMUST00000073339(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0007613"(memory)|go:"GO:0008306"(associative learning)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905809"(negative regulation of synapse organization)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O55022|reactome:R-MMU-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:JJb2/xwky1pSXG+DPfq5+XVmbcw10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:P50172	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320920|ensembl:ENSMUSP00000016338|ensembl:ENSMUSP00000125620	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:dhi1_mouse(display_long)|uniprotkb:Hsd11b1(gene name)|psi-mi:Hsd11b1(display_short)|uniprotkb:Hsd11(gene name synonym)|uniprotkb:11-beta-hydroxysteroid dehydrogenase 1(gene name synonym)|uniprotkb:11beta-HSD1A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_001038216.1|refseq:NP_032314.2|ensembl:ENSMUSG00000016194(gene)|ensembl:ENSMUST00000016338(transcript)|ensembl:ENSMUST00000161737(transcript)|go:"GO:0003845"("11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030324"(lung development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045177"(apical part of cell)|go:"GO:0050661"(NADP binding)|go:"GO:0070524"("11-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P50172|rcsb pdb:1Y5M|rcsb pdb:1Y5R|rcsb pdb:3GMD|rcsb pdb:4K26|rcsb pdb:4NMH|rcsb pdb:5PGZ|rcsb pdb:5QIJ|reactome:R-MMU-194002|go:"GO:0043231"(intracellular membrane-bounded organelle)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:vciyVfWedFkHfdzWngUbBdRK/J010090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:Q64459	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320900|ensembl:ENSMUSP00000037665	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:cp3ab_mouse(display_long)|uniprotkb:Cyp3a11(gene name)|psi-mi:Cyp3a11(display_short)|uniprotkb:Cyp3a-11(gene name synonym)|uniprotkb:CYPIIIA11(gene name synonym)|uniprotkb:Cytochrome P-450IIIAM1(gene name synonym)|uniprotkb:Cytochrome P-450UT(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_031844.1|ensembl:ENSMUSG00000056035(gene)|ensembl:ENSMUST00000035918(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0008401"(retinoic acid 4-hydroxylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|go:"GO:0032451"(demethylase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0101020"(estrogen 16-alpha-hydroxylase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002402(Cytochrome P450, E-class, group II)|interpro:IPR008072(Cytochrome P450, E-class, CYP3A)|interpro:IPR017972|interpro:IPR036396|mint:Q64459|reactome:R-MMU-211981|reactome:R-MMU-5423646|reactome:R-MMU-9027307|go:"GO:0050649"(testosterone 6-beta-hydroxylase activity)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:HzIYdf39IckB+AWc8HXa7nSAj6M10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:O88451	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320845|ensembl:ENSMUSP00000039252	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:rdh7_mouse(display_long)|uniprotkb:Rdh7(gene name)|psi-mi:Rdh7(display_short)|uniprotkb:Crad2(gene name synonym)|uniprotkb:Cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme 2(gene name synonym)|uniprotkb:Cis-retinol/androgen dehydrogenase type 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_001144221.1|refseq:NP_059501.1|ensembl:ENSMUSG00000040134(gene)|ensembl:ENSMUST00000047199(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004745"(NAD-retinol dehydrogenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0042572"(retinol metabolic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:sGfo1le/T5P7fT+2jyNi+1+qiv410090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:Q8CIM7	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4321011|uniprotkb:Q9DBJ5	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:cp2dq_mouse(display_long)|uniprotkb:Cyp2d26(gene name)|psi-mi:Cyp2d26(display_short)|uniprotkb:Cyp2d-26(gene name synonym)|uniprotkb:CYPIID26(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_083838.1|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008069(Cytochrome P450, E-class, group I, CYP2D-like)|interpro:IPR036396|mint:Q8CIM7|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0042493"|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:qwToD4eWmOx0/+RIx1MPpkfNuCw10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:Q9DD20	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320968|uniprotkb:Q78ID2|ensembl:ENSMUSP00000026398	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:met7b_mouse(display_long)|uniprotkb:Mettl7b(gene name)|psi-mi:Mettl7b(display_short)|uniprotkb:Methyltransferase-like protein 7B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_082129.2|ensembl:ENSMUSG00000025347(gene)|ensembl:ENSMUST00000026398(transcript)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018708"(thiol S-methyltransferase activity)|go:"GO:0032259"(methylation)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q9DD20	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:8mQjke9g31iMlXsPyXARQqQHKs810090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:P08226	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-1634131|ensembl:ENSMUSP00000003066|ensembl:ENSMUSP00000133302|ensembl:ENSMUSP00000133371|ensembl:ENSMUSP00000134160	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:apoe_mouse(display_long)|uniprotkb:Apoe(gene name)|psi-mi:Apoe(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_001292748.1|refseq:NP_001292772.1|refseq:NP_001292773.1|refseq:NP_033826.2|ensembl:ENSMUSG00000002985(gene)|ensembl:ENSMUST00000003066(transcript)|ensembl:ENSMUST00000173739(transcript)|ensembl:ENSMUST00000174064(transcript)|ensembl:ENSMUST00000174355(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010877"(lipid transport involved in lipid storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016209"(antioxidant activity)|go:"GO:0017038"(protein import)|go:"GO:0019068"(virion assembly)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030425"(dendrite)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032805"(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034447"(very-low-density lipoprotein particle clearance)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046848"(hydroxyapatite binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0046911"(metal chelating activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0051651"(maintenance of location in cell)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061771"(response to caloric restriction)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0071830"(triglyceride-rich lipoprotein particle clearance)|go:"GO:0071831"(intermediate-density lipoprotein particle clearance)|go:"GO:0072359"(circulatory system development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0090209"(negative regulation of triglyceride metabolic process)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901627"(negative regulation of postsynaptic membrane organization)|go:"GO:1901631"(positive regulation of presynaptic membrane organization)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1902999"(negative regulation of phospholipid efflux)|go:"GO:1903001"(negative regulation of lipid transport across blood-brain barrier)|go:"GO:1903002"(positive regulation of lipid transport across blood-brain barrier)|go:"GO:1905855"(positive regulation of heparan sulfate binding)|go:"GO:1905860"(positive regulation of heparan sulfate proteoglycan binding)|go:"GO:1905890"(regulation of cellular response to very-low-density lipoprotein particle stimulus)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1990777"(lipoprotein particle)|go:"GO:2000822"(regulation of behavioral fear response)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P08226|rcsb pdb:1YA9|reactome:R-MMU-3000480|reactome:R-MMU-381426|reactome:R-MMU-8957275|reactome:R-MMU-8963888|reactome:R-MMU-8963901|reactome:R-MMU-8964026|reactome:R-MMU-8964058|reactome:R-MMU-975634	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:fJDvqSxzmdZmV8t1M4yp9jw1jvU10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:P97872	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320824|uniprotkb:Q8R1W6|ensembl:ENSMUSP00000029729|ensembl:ENSMUSP00000102664|ensembl:ENSMUSP00000102665	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:fmo5_mouse(display_long)|uniprotkb:Fmo5(gene name)|psi-mi:Fmo5(display_short)|uniprotkb:Dimethylaniline oxidase 5(gene name synonym)|uniprotkb:Hepatic flavin-containing monooxygenase 5(gene name synonym)|uniprotkb:Dimethylaniline monooxygenase [N-oxide-forming] 5(gene name synonym)|uniprotkb:NAPDH oxidase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_001155235.1|refseq:NP_001155237.1|refseq:NP_034362.2|refseq:XP_006501058.1|ensembl:ENSMUSG00000028088(gene)|ensembl:ENSMUST00000029729(transcript)|ensembl:ENSMUST00000107049(transcript)|ensembl:ENSMUST00000107050(transcript)|go:"GO:0004031"(aldehyde oxidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004499"(N,N-dimethylaniline monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017144"|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR002257("Flavin-containing monooxygenase (FMO) 5")|interpro:IPR020946|interpro:IPR036188|mint:P97872	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:Z4EY0BHh+YUL6cKmVZgayGIouUA10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:P24456	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320946|uniprotkb:Q64490|ensembl:ENSMUSP00000072555	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:cp2da_mouse(display_long)|uniprotkb:Cyp2d10(gene name)|psi-mi:Cyp2d10(display_short)|uniprotkb:Cyp2d-10(gene name synonym)|uniprotkb:CYPIID10(gene name synonym)|uniprotkb:Cytochrome P450-16-alpha(gene name synonym)|uniprotkb:Cytochrome P450CB(gene name synonym)|uniprotkb:Testosterone 16-alpha hydroxylase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_034135.2|ensembl:ENSMUSG00000094806(gene)|ensembl:ENSMUST00000072776(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR036396|mint:P24456|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008069(Cytochrome P450, E-class, group I, CYP2D-like)|interpro:IPR017972	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:wLRneXE7gasseBnmpNLCypVQWPc10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P00181	uniprotkb:Q62452	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320992|uniprotkb:E9QN27|uniprotkb:Q6XL44|uniprotkb:A6H6W3|ensembl:ENSMUSP00000073444	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:ud19_mouse(display_long)|uniprotkb:Ugt1a9(gene name)|psi-mi:Ugt1a9(display_short)|uniprotkb:Ugt1(gene name synonym)|uniprotkb:Ugt1a12(gene name synonym)|uniprotkb:UDP-glucuronosyltransferase 1-7(gene name synonym)|uniprotkb:UGT1A12(gene name synonym)|uniprotkb:UGTP4(gene name synonym)|uniprotkb:UDP-glucuronosyltransferase 1-9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4320575|imex:IM-16547-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_964006.2|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0052696"(flavonoid glucuronidation)|go:"GO:0052697"(xenobiotic glucuronidation)|interpro:IPR002213(UDP-glucuronosyl/UDP-glucosyltransferase)|interpro:IPR035595|mint:Q62452|reactome:R-MMU-156588|ensembl:ENSMUSG00000090175(gene)|ensembl:ENSMUST00000073772(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005496"(steroid binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1,  Table 1 ,  Supplementary Table S1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:9wRlHmQ+YqLIbjAr/6ErGdEfxeo10090	intact-crc:76E22F6AC7527EFC|rigid:OS+3lT2qSFot7+7dGIKoBRqPats	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P41216	uniprotkb:Q61335	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-4321208|uniprotkb:Q9D0E9|uniprotkb:Q9D8G7|uniprotkb:A2ALM8|ensembl:ENSMUSP00000002091	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:bap31_mouse(display_long)|uniprotkb:Bcap31(gene name)|psi-mi:Bcap31(display_short)|uniprotkb:Bap31(gene name synonym)|uniprotkb:p28(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321412|imex:IM-16547-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	refseq:XP_011245902.1|refseq:NP_036190.2|refseq:NP_001300627.1|refseq:XP_006528111.1|ensembl:ENSMUSG00000002015(gene)|ensembl:ENSMUST00000002091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:Q61335|reactome:R-MMU-111465|reactome:R-MMU-75153|reactome:R-MMU-8980692|reactome:R-MMU-983170|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:Bznhime2O4T70teBrviYu3Xrq5U10090	intact-crc:D7B92C0907026C7D|rigid:3RL3kp2vD99/N2cpcitLCyq+d6w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41216	uniprotkb:P00181	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-4320576|uniprotkb:Q28683	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321412|imex:IM-16547-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	intact-crc:D7B92C0907026C7D|rigid:3RL3kp2vD99/N2cpcitLCyq+d6w	false	-	flag tag:?-?|his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41216	uniprotkb:P24456	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-4320946|uniprotkb:Q64490|ensembl:ENSMUSP00000072555	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:cp2da_mouse(display_long)|uniprotkb:Cyp2d10(gene name)|psi-mi:Cyp2d10(display_short)|uniprotkb:Cyp2d-10(gene name synonym)|uniprotkb:CYPIID10(gene name synonym)|uniprotkb:Cytochrome P450-16-alpha(gene name synonym)|uniprotkb:Cytochrome P450CB(gene name synonym)|uniprotkb:Testosterone 16-alpha hydroxylase(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321412|imex:IM-16547-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	refseq:NP_034135.2|ensembl:ENSMUSG00000094806(gene)|ensembl:ENSMUST00000072776(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR036396|mint:P24456|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008069(Cytochrome P450, E-class, group I, CYP2D-like)|interpro:IPR017972	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:wLRneXE7gasseBnmpNLCypVQWPc10090	intact-crc:D7B92C0907026C7D|rigid:3RL3kp2vD99/N2cpcitLCyq+d6w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41216	uniprotkb:Q64459	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-4320900|ensembl:ENSMUSP00000037665	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:cp3ab_mouse(display_long)|uniprotkb:Cyp3a11(gene name)|psi-mi:Cyp3a11(display_short)|uniprotkb:Cyp3a-11(gene name synonym)|uniprotkb:CYPIIIA11(gene name synonym)|uniprotkb:Cytochrome P-450IIIAM1(gene name synonym)|uniprotkb:Cytochrome P-450UT(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321412|imex:IM-16547-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	refseq:NP_031844.1|ensembl:ENSMUSG00000056035(gene)|ensembl:ENSMUST00000035918(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0008401"(retinoic acid 4-hydroxylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|go:"GO:0032451"(demethylase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0101020"(estrogen 16-alpha-hydroxylase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002402(Cytochrome P450, E-class, group II)|interpro:IPR008072(Cytochrome P450, E-class, CYP3A)|interpro:IPR017972|interpro:IPR036396|mint:Q64459|reactome:R-MMU-211981|reactome:R-MMU-5423646|reactome:R-MMU-9027307|go:"GO:0050649"(testosterone 6-beta-hydroxylase activity)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:HzIYdf39IckB+AWc8HXa7nSAj6M10090	intact-crc:D7B92C0907026C7D|rigid:3RL3kp2vD99/N2cpcitLCyq+d6w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41216	uniprotkb:P50172	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-4320920|ensembl:ENSMUSP00000016338|ensembl:ENSMUSP00000125620	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:dhi1_mouse(display_long)|uniprotkb:Hsd11b1(gene name)|psi-mi:Hsd11b1(display_short)|uniprotkb:Hsd11(gene name synonym)|uniprotkb:11-beta-hydroxysteroid dehydrogenase 1(gene name synonym)|uniprotkb:11beta-HSD1A(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321412|imex:IM-16547-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	refseq:NP_001038216.1|refseq:NP_032314.2|ensembl:ENSMUSG00000016194(gene)|ensembl:ENSMUST00000016338(transcript)|ensembl:ENSMUST00000161737(transcript)|go:"GO:0003845"("11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030324"(lung development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045177"(apical part of cell)|go:"GO:0050661"(NADP binding)|go:"GO:0070524"("11-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P50172|rcsb pdb:1Y5M|rcsb pdb:1Y5R|rcsb pdb:3GMD|rcsb pdb:4K26|rcsb pdb:4NMH|rcsb pdb:5PGZ|rcsb pdb:5QIJ|reactome:R-MMU-194002|go:"GO:0043231"(intracellular membrane-bounded organelle)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:vciyVfWedFkHfdzWngUbBdRK/J010090	intact-crc:D7B92C0907026C7D|rigid:3RL3kp2vD99/N2cpcitLCyq+d6w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41216	uniprotkb:P97872	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-4320824|uniprotkb:Q8R1W6|ensembl:ENSMUSP00000029729|ensembl:ENSMUSP00000102664|ensembl:ENSMUSP00000102665	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:fmo5_mouse(display_long)|uniprotkb:Fmo5(gene name)|psi-mi:Fmo5(display_short)|uniprotkb:Dimethylaniline oxidase 5(gene name synonym)|uniprotkb:Hepatic flavin-containing monooxygenase 5(gene name synonym)|uniprotkb:Dimethylaniline monooxygenase [N-oxide-forming] 5(gene name synonym)|uniprotkb:NAPDH oxidase(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321412|imex:IM-16547-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	refseq:NP_001155235.1|refseq:NP_001155237.1|refseq:NP_034362.2|refseq:XP_006501058.1|ensembl:ENSMUSG00000028088(gene)|ensembl:ENSMUST00000029729(transcript)|ensembl:ENSMUST00000107049(transcript)|ensembl:ENSMUST00000107050(transcript)|go:"GO:0004031"(aldehyde oxidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004499"(N,N-dimethylaniline monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017144"|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR002257("Flavin-containing monooxygenase (FMO) 5")|interpro:IPR020946|interpro:IPR036188|mint:P97872	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:Z4EY0BHh+YUL6cKmVZgayGIouUA10090	intact-crc:D7B92C0907026C7D|rigid:3RL3kp2vD99/N2cpcitLCyq+d6w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41216	uniprotkb:Q9D379	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-4320880|uniprotkb:P97869|ensembl:ENSMUSP00000047551	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:hyep_mouse(display_long)|uniprotkb:Ephx1(gene name)|psi-mi:Ephx1(display_short)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321412|imex:IM-16547-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	refseq:NP_034275.1|refseq:NP_001299847.1|ensembl:ENSMUSG00000038776(gene)|ensembl:ENSMUST00000036928(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0034312"(diol biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR010497(Epoxide hydrolase, N-terminal)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|mint:Q9D379|reactome:R-MMU-211945|go:"GO:0097176"(epoxide metabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:Ha5pbdo0GK7HPNskQw6y0dJjgBg10090	intact-crc:D7B92C0907026C7D|rigid:3RL3kp2vD99/N2cpcitLCyq+d6w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41216	uniprotkb:Q9DCN2	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-4321444|ensembl:ENSMUSP00000018186	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:nb5r3_mouse(display_long)|uniprotkb:Cyb5r3(gene name)|psi-mi:Cyb5r3(display_short)|uniprotkb:Dia1(gene name synonym)|uniprotkb:Diaphorase-1(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321412|imex:IM-16547-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	refseq:NP_084063.1|refseq:XP_006520346.1|ensembl:ENSMUSG00000018042(gene)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|ensembl:ENSMUST00000018186(transcript)|go:"GO:0071949"(FAD binding)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|go:"GO:0051287"(NAD binding)|mint:Q9DCN2|reactome:R-MMU-196836|reactome:R-MMU-211945|reactome:R-MMU-6798695|dip:DIP-57517N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:72QkmF4NeAFyp0tOl6Vxsol0Z6410090	intact-crc:D7B92C0907026C7D|rigid:3RL3kp2vD99/N2cpcitLCyq+d6w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41216	uniprotkb:O55022	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	intact:EBI-770756|uniprotkb:Q99JN0|ensembl:ENSMUSP00000073061	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:pgrc1_mouse(display_long)|uniprotkb:Pgrmc1(gene name)|psi-mi:Pgrmc1(display_short)|uniprotkb:Pgrmc(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321412|imex:IM-16547-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	refseq:NP_058063.2|ensembl:ENSMUSG00000006373(gene)|ensembl:ENSMUST00000073339(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0007613"(memory)|go:"GO:0008306"(associative learning)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905809"(negative regulation of synapse organization)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O55022|reactome:R-MMU-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rogid:JJb2/xwky1pSXG+DPfq5+XVmbcw10090	intact-crc:D7B92C0907026C7D|rigid:3RL3kp2vD99/N2cpcitLCyq+d6w	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:Q9D379	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320880|uniprotkb:P97869|ensembl:ENSMUSP00000047551	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:hyep_mouse(display_long)|uniprotkb:Ephx1(gene name)|psi-mi:Ephx1(display_short)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321193|imex:IM-16547-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_034275.1|refseq:NP_001299847.1|ensembl:ENSMUSG00000038776(gene)|ensembl:ENSMUST00000036928(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0034312"(diol biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR010497(Epoxide hydrolase, N-terminal)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|mint:Q9D379|reactome:R-MMU-211945|go:"GO:0097176"(epoxide metabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:Ha5pbdo0GK7HPNskQw6y0dJjgBg10090	intact-crc:721102E483558F9A|rigid:MnIUSJxuWOZyov/5ROOQsmE/+4c	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:P97872	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320824|uniprotkb:Q8R1W6|ensembl:ENSMUSP00000029729|ensembl:ENSMUSP00000102664|ensembl:ENSMUSP00000102665	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:fmo5_mouse(display_long)|uniprotkb:Fmo5(gene name)|psi-mi:Fmo5(display_short)|uniprotkb:Dimethylaniline oxidase 5(gene name synonym)|uniprotkb:Hepatic flavin-containing monooxygenase 5(gene name synonym)|uniprotkb:Dimethylaniline monooxygenase [N-oxide-forming] 5(gene name synonym)|uniprotkb:NAPDH oxidase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321193|imex:IM-16547-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_001155235.1|refseq:NP_001155237.1|refseq:NP_034362.2|refseq:XP_006501058.1|ensembl:ENSMUSG00000028088(gene)|ensembl:ENSMUST00000029729(transcript)|ensembl:ENSMUST00000107049(transcript)|ensembl:ENSMUST00000107050(transcript)|go:"GO:0004031"(aldehyde oxidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004499"(N,N-dimethylaniline monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017144"|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR002257("Flavin-containing monooxygenase (FMO) 5")|interpro:IPR020946|interpro:IPR036188|mint:P97872	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:Z4EY0BHh+YUL6cKmVZgayGIouUA10090	intact-crc:721102E483558F9A|rigid:MnIUSJxuWOZyov/5ROOQsmE/+4c	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:Q61595	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-775369|uniprotkb:Q8BG49|uniprotkb:Q8BHF4|uniprotkb:Q8BHM8|uniprotkb:Q8C9Y5|uniprotkb:Q8CG51|uniprotkb:Q8CG52|uniprotkb:Q8CG53|uniprotkb:Q8CG54|uniprotkb:Q8CG55|uniprotkb:Q8CG56|uniprotkb:Q8CG57|uniprotkb:Q8CG58|uniprotkb:Q8CG59|uniprotkb:Q8CG60|uniprotkb:Q8CG61|uniprotkb:Q8CG62|uniprotkb:Q8CG63	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:ktn1_mouse(display_long)|uniprotkb:Ktn1(gene name)|psi-mi:Ktn1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321193|imex:IM-16547-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_032503.2|refseq:NP_001280564.1|refseq:NP_001280565.1|interpro:IPR024854|refseq:NP_001334448.1|refseq:NP_001334449.1|refseq:NP_001334450.1|refseq:NP_001334452.1|refseq:NP_001334453.1|refseq:NP_001334454.1|refseq:NP_001334455.1|refseq:NP_001334456.1|refseq:NP_001334457.1|mint:Q61595|interpro:IPR007794(Ribosome receptor lysine or proline rich)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|reactome:R-MMU-381426|reactome:R-MMU-5625970|reactome:R-MMU-8957275|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013408|reactome:R-MMU-9696264|reactome:R-MMU-9696270	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:xgS8/yfp5yj+gPyaC6a/gmSrxTA10090	intact-crc:721102E483558F9A|rigid:MnIUSJxuWOZyov/5ROOQsmE/+4c	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:Q61335	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4321208|uniprotkb:Q9D0E9|uniprotkb:Q9D8G7|uniprotkb:A2ALM8|ensembl:ENSMUSP00000002091	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:bap31_mouse(display_long)|uniprotkb:Bcap31(gene name)|psi-mi:Bcap31(display_short)|uniprotkb:Bap31(gene name synonym)|uniprotkb:p28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321193|imex:IM-16547-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:XP_011245902.1|refseq:NP_036190.2|refseq:NP_001300627.1|refseq:XP_006528111.1|ensembl:ENSMUSG00000002015(gene)|ensembl:ENSMUST00000002091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:Q61335|reactome:R-MMU-111465|reactome:R-MMU-75153|reactome:R-MMU-8980692|reactome:R-MMU-983170|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:Bznhime2O4T70teBrviYu3Xrq5U10090	intact-crc:721102E483558F9A|rigid:MnIUSJxuWOZyov/5ROOQsmE/+4c	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:P41216	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321193|imex:IM-16547-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	intact-crc:721102E483558F9A|rigid:MnIUSJxuWOZyov/5ROOQsmE/+4c	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:P50172	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320920|ensembl:ENSMUSP00000016338|ensembl:ENSMUSP00000125620	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:dhi1_mouse(display_long)|uniprotkb:Hsd11b1(gene name)|psi-mi:Hsd11b1(display_short)|uniprotkb:Hsd11(gene name synonym)|uniprotkb:11-beta-hydroxysteroid dehydrogenase 1(gene name synonym)|uniprotkb:11beta-HSD1A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321193|imex:IM-16547-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_001038216.1|refseq:NP_032314.2|ensembl:ENSMUSG00000016194(gene)|ensembl:ENSMUST00000016338(transcript)|ensembl:ENSMUST00000161737(transcript)|go:"GO:0003845"("11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030324"(lung development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045177"(apical part of cell)|go:"GO:0050661"(NADP binding)|go:"GO:0070524"("11-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P50172|rcsb pdb:1Y5M|rcsb pdb:1Y5R|rcsb pdb:3GMD|rcsb pdb:4K26|rcsb pdb:4NMH|rcsb pdb:5PGZ|rcsb pdb:5QIJ|reactome:R-MMU-194002|go:"GO:0043231"(intracellular membrane-bounded organelle)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:vciyVfWedFkHfdzWngUbBdRK/J010090	intact-crc:721102E483558F9A|rigid:MnIUSJxuWOZyov/5ROOQsmE/+4c	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:Q62452	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320992|uniprotkb:E9QN27|uniprotkb:Q6XL44|uniprotkb:A6H6W3|ensembl:ENSMUSP00000073444	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:ud19_mouse(display_long)|uniprotkb:Ugt1a9(gene name)|psi-mi:Ugt1a9(display_short)|uniprotkb:Ugt1(gene name synonym)|uniprotkb:Ugt1a12(gene name synonym)|uniprotkb:UDP-glucuronosyltransferase 1-7(gene name synonym)|uniprotkb:UGT1A12(gene name synonym)|uniprotkb:UGTP4(gene name synonym)|uniprotkb:UDP-glucuronosyltransferase 1-9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321193|imex:IM-16547-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_964006.2|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0052696"(flavonoid glucuronidation)|go:"GO:0052697"(xenobiotic glucuronidation)|interpro:IPR002213(UDP-glucuronosyl/UDP-glucosyltransferase)|interpro:IPR035595|mint:Q62452|reactome:R-MMU-156588|ensembl:ENSMUSG00000090175(gene)|ensembl:ENSMUST00000073772(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005496"(steroid binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:9wRlHmQ+YqLIbjAr/6ErGdEfxeo10090	intact-crc:721102E483558F9A|rigid:MnIUSJxuWOZyov/5ROOQsmE/+4c	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:Q64459	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320900|ensembl:ENSMUSP00000037665	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:cp3ab_mouse(display_long)|uniprotkb:Cyp3a11(gene name)|psi-mi:Cyp3a11(display_short)|uniprotkb:Cyp3a-11(gene name synonym)|uniprotkb:CYPIIIA11(gene name synonym)|uniprotkb:Cytochrome P-450IIIAM1(gene name synonym)|uniprotkb:Cytochrome P-450UT(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321193|imex:IM-16547-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_031844.1|ensembl:ENSMUSG00000056035(gene)|ensembl:ENSMUST00000035918(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0008401"(retinoic acid 4-hydroxylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|go:"GO:0032451"(demethylase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0101020"(estrogen 16-alpha-hydroxylase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002402(Cytochrome P450, E-class, group II)|interpro:IPR008072(Cytochrome P450, E-class, CYP3A)|interpro:IPR017972|interpro:IPR036396|mint:Q64459|reactome:R-MMU-211981|reactome:R-MMU-5423646|reactome:R-MMU-9027307|go:"GO:0050649"(testosterone 6-beta-hydroxylase activity)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:HzIYdf39IckB+AWc8HXa7nSAj6M10090	intact-crc:721102E483558F9A|rigid:MnIUSJxuWOZyov/5ROOQsmE/+4c	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:P24456	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-4320946|uniprotkb:Q64490|ensembl:ENSMUSP00000072555	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:cp2da_mouse(display_long)|uniprotkb:Cyp2d10(gene name)|psi-mi:Cyp2d10(display_short)|uniprotkb:Cyp2d-10(gene name synonym)|uniprotkb:CYPIID10(gene name synonym)|uniprotkb:Cytochrome P450-16-alpha(gene name synonym)|uniprotkb:Cytochrome P450CB(gene name synonym)|uniprotkb:Testosterone 16-alpha hydroxylase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321193|imex:IM-16547-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_034135.2|ensembl:ENSMUSG00000094806(gene)|ensembl:ENSMUST00000072776(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR036396|mint:P24456|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008069(Cytochrome P450, E-class, group I, CYP2D-like)|interpro:IPR017972	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:wLRneXE7gasseBnmpNLCypVQWPc10090	intact-crc:721102E483558F9A|rigid:MnIUSJxuWOZyov/5ROOQsmE/+4c	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00181	uniprotkb:P37040	intact:EBI-4320576|uniprotkb:Q28683	intact:EBI-647134|ensembl:ENSMUSP00000005651	psi-mi:cp2c2_rabit(display_long)|uniprotkb:CYP2C2(gene name)|psi-mi:CYP2C2(display_short)|uniprotkb:CYPIIC2(gene name synonym)|uniprotkb:Cytochrome P450 PBc2(gene name synonym)|uniprotkb:Cytochrome P450 PHP2(gene name synonym)|uniprotkb:Laurate omega-1 hydroxylase(gene name synonym)	psi-mi:ncpr_mouse(display_long)|uniprotkb:Por(gene name)|psi-mi:Por(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2011)	pubmed:21751364|imex:IM-16547	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4321193|imex:IM-16547-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036396|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|refseq:NP_001164584.1|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	refseq:NP_032924.1|refseq:XP_006504461.1|refseq:XP_006504462.1|ensembl:ENSMUSG00000005514(gene)|ensembl:ENSMUST00000005651(transcript)|go:"GO:0003420"(regulation of growth plate cartilage chondrocyte proliferation)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007584"(response to nutrient)|go:"GO:0008941"(nitric oxide dioxygenase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009725"(response to hormone)|go:"GO:0009812"(flavonoid metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0016787"(hydrolase activity)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019899"(enzyme binding)|go:"GO:0022900"(electron transport chain)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032770"(positive regulation of monooxygenase activity)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043602"(nitrate catabolic process)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046210"(nitric oxide catabolic process)|go:"GO:0047726"(iron-cytochrome-c reductase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0070988"(demethylation)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090031"(positive regulation of steroid hormone biosynthetic process)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090346"(cellular organofluorine metabolic process)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR029039|interpro:IPR039261|mint:P37040	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2011/08/03	2014/10/16	rogid:nHbsBzEexhQa7Nx5Qda9Lfs30q49986	rogid:vAbEMJjVNV+LFIFubNftcQVxDHQ10090	intact-crc:721102E483558F9A|rigid:MnIUSJxuWOZyov/5ROOQsmE/+4c	false	his tag:?-?|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)