#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q91VJ4 uniprotkb:Q8VDP3 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4395022|imex:IM-17198-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY - - - figure legend:1c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-l cells)|taxid:10090(Mus musculus embryo fibroblast, Moloney Sarcoma Virus transformed) - 2011/08/31 2014/10/16 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 intact-crc:BA05C0FD8F12E200|rigid:Q8FN69J5DIQM7Ql2a8O1SfCVP7I false - ha tag:c-c|flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8VDP3 uniprotkb:Q8VDP3 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4394960|imex:IM-17198-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY - - - figure legend:table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-l cells)|taxid:10090(Mus musculus embryo fibroblast, Moloney Sarcoma Virus transformed) - 2011/08/31 2014/10/16 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 intact-crc:6ECB861968E845E1|rigid:jBnDcYLWChTal/ltBuSe3AspCGc false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8VDP3 uniprotkb:P42209 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 intact:EBI-4394915|uniprotkb:B2RU74|ensembl:ENSMUSP00000101921 psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:sept1_mouse(display_long)|uniprotkb:Diff6(gene name synonym)|uniprotkb:Differentiation protein 6(gene name synonym)|uniprotkb:Peanut-like protein 3(gene name synonym)|uniprotkb:Pnutl3(gene name synonym)|uniprotkb:Sept1(gene name synonym)|uniprotkb:Septin1(gene name)|psi-mi:Septin1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4394960|imex:IM-17198-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY refseq:NP_059489.2|ensembl:ENSMUSG00000000486(gene)|ensembl:ENSMUST00000106314(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005940"(septin ring)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051311"(meiotic metaphase plate congression)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072687"(meiotic spindle)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0061640"(cytoskeleton-dependent cytokinesis) - - - figure legend:table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-l cells)|taxid:10090(Mus musculus embryo fibroblast, Moloney Sarcoma Virus transformed) - 2011/08/31 2014/10/16 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 rogid:icR44nnnElSnXUfA6yxeQqpLSns10090 intact-crc:6ECB861968E845E1|rigid:jBnDcYLWChTal/ltBuSe3AspCGc false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8VDP3 uniprotkb:Q91VJ4 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4394960|imex:IM-17198-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 - - - figure legend:table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-l cells)|taxid:10090(Mus musculus embryo fibroblast, Moloney Sarcoma Virus transformed) - 2011/08/31 2014/10/16 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 intact-crc:6ECB861968E845E1|rigid:jBnDcYLWChTal/ltBuSe3AspCGc false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8VDP3 uniprotkb:Q80X90 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 intact:EBI-688023|intact:EBI-777273|uniprotkb:E9QNV9|uniprotkb:Q8VHX4|uniprotkb:Q8VHX7|uniprotkb:Q99KY3|ensembl:ENSMUSP00000052020 psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:flnb_mouse(display_long)|uniprotkb:Flnb(gene name)|psi-mi:Flnb(display_short)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4394960|imex:IM-17198-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY refseq:NP_001074896.1|ensembl:ENSMUSG00000025278(gene)|ensembl:ENSMUST00000052678(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:Q80X90|reactome:R-MMU-1169408|go:"GO:0005737"(cytoplasm) - - - figure legend:table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-l cells)|taxid:10090(Mus musculus embryo fibroblast, Moloney Sarcoma Virus transformed) - 2011/08/31 2014/10/16 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 rogid:A5bnyO/GwzIgn56NbxZGMkAWYk410090 intact-crc:6ECB861968E845E1|rigid:jBnDcYLWChTal/ltBuSe3AspCGc false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q91VJ4 uniprotkb:Q8VDP3 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4395342|imex:IM-17198-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY - - - figure legend:2e and 2f|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/31 2014/10/16 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 intact-crc:202F786708348257|rigid:Q8FN69J5DIQM7Ql2a8O1SfCVP7I false sufficient binding region:83-465|flag tag:n-n|necessary binding region:381-465(IPR000961) ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q91VJ4 uniprotkb:Q8VDP3 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4395071|imex:IM-17198-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY - - - figure legend:1d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/31 2014/10/16 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 intact-crc:5BA4DB9B9112CA42|rigid:Q8FN69J5DIQM7Ql2a8O1SfCVP7I false flag tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q91VJ4 uniprotkb:Q13043 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4395384|imex:IM-17198-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N - - - figure legend:7a|comment:"Binding of mical1 reduces phosphorylation of ndr1 (fig. 7b)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/31 2014/10/16 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 intact-crc:B9BF99298FBC0DFE|rigid:taURpA51olEJITrvJS4XRdcV8XI false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q91VJ4 uniprotkb:Q8VDP3 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4395384|imex:IM-17198-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY - - - figure legend:7a|comment:"Binding of mical1 reduces phosphorylation of ndr1 (fig. 7b)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/31 2014/10/16 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 intact-crc:B9BF99298FBC0DFE|rigid:taURpA51olEJITrvJS4XRdcV8XI false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8VDP3 uniprotkb:Q91VJ4 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4395318|imex:IM-17198-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 - - - figure legend:2b and 2c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/31 2014/10/16 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 intact-crc:BE9697F9FB4974E1|rigid:Q8FN69J5DIQM7Ql2a8O1SfCVP7I false ha tag:n-n|sufficient binding region:627-746(IPR001781)|sufficient binding region:747-1048 flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A4GW50 uniprotkb:Q8VDP3 intact:EBI-4404035|uniprotkb:D4AA09|ensembl:ENSRNOP00000002502|ensembl:ENSRNOP00000068621 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 psi-mi:a4gw50_rat(display_long)|uniprotkb:Stk38l(gene name)|psi-mi:Stk38l(display_short)|uniprotkb:rCG_29601(orf name) psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4395079|imex:IM-17198-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1564793|refseq:NP_001076805.1|refseq:XP_017448391.1|ensembl:ENSRNOG00000001828(gene)|ensembl:ENSRNOT00000002502(transcript)|ensembl:ENSRNOT00000086813(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051128"(regulation of cellular component organization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892 refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY - note:"This is NDR2 (serine-threonine kinase 38 like protein). Inferred from similarity with the mouse homolog." - figure legend:1e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/31 2014/10/16 rogid:CvCno16gHKhQa85EaskK8UJGwWI10116 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 intact-crc:00C585744F55D836|rigid:7sCSPW9198NEqa05sjah+zReTf8 false flag tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q91VJ4 uniprotkb:Q8VDP3 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4395370|imex:IM-17198-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY - - - figure legend:5a and 5b|comment:Binding of mical1 reduces phosphorylation of ndr1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/31 2014/10/16 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 intact-crc:A5D6F84640A8AF37|rigid:Q8FN69J5DIQM7Ql2a8O1SfCVP7I false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A4GW50 uniprotkb:Q8VDP3 intact:EBI-4404035|uniprotkb:D4AA09|ensembl:ENSRNOP00000002502|ensembl:ENSRNOP00000068621 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 psi-mi:a4gw50_rat(display_long)|uniprotkb:Stk38l(gene name)|psi-mi:Stk38l(display_short)|uniprotkb:rCG_29601(orf name) psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4395133|imex:IM-17198-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1564793|refseq:NP_001076805.1|refseq:XP_017448391.1|ensembl:ENSRNOG00000001828(gene)|ensembl:ENSRNOT00000002502(transcript)|ensembl:ENSRNOT00000086813(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051128"(regulation of cellular component organization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892 refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY - note:"This is NDR2 (serine-threonine kinase 38 like protein). Inferred from similarity with the mouse homolog." - figure legend:1f and 1g|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/08/31 2014/10/16 rogid:CvCno16gHKhQa85EaskK8UJGwWI10116 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 intact-crc:DBAF939F53F2FBB1|rigid:7sCSPW9198NEqa05sjah+zReTf8 false glutathione s tranferase tag:n-n ha tag:n-n|sufficient binding region:747-1048 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8VDP3 uniprotkb:Q91VJ4 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4395314|imex:IM-17198-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 - - - figure legend:1h|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-l cells)|taxid:10090(Mus musculus embryo fibroblast, Moloney Sarcoma Virus transformed) - 2011/08/31 2014/10/16 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 intact-crc:D27AD374F9AE52FD|rigid:Q8FN69J5DIQM7Ql2a8O1SfCVP7I false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8VDP3 uniprotkb:Q91VJ4 intact:EBI-4394891|uniprotkb:D3Z4C6|uniprotkb:E9PXR1|uniprotkb:Q3TB77|uniprotkb:Q3TBH9|uniprotkb:Q3TX89|ensembl:ENSMUSP00000019967 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 psi-mi:mica1_mouse(display_long)|uniprotkb:Mical1(gene name)|psi-mi:Mical1(display_short)|uniprotkb:Mical(gene name synonym)|uniprotkb:Nical(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 1(gene name synonym)|uniprotkb:NEDD9-interacting protein with calponin homology and LIM domains(gene name synonym) psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4396006|imex:IM-17198-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612188.1|refseq:XP_011241439.1|refseq:NP_001157905.1|ensembl:ENSMUSG00000019823(gene)|ensembl:ENSMUST00000019967(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019417"(sulfur oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1990026"(hippocampal mossy fiber expansion)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2C4C|rcsb pdb:4TXI|rcsb pdb:4TXK|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2BRA|rcsb pdb:2BRY go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 - - - figure legend:1h|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-l cells)|taxid:10090(Mus musculus embryo fibroblast, Moloney Sarcoma Virus transformed) - 2011/08/31 2014/10/16 rogid:opn3mhSuO/pNvsxBHz04UOqCuK810090 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 intact-crc:3AEEEBC3292B2D45|rigid:Q8FN69J5DIQM7Ql2a8O1SfCVP7I false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4GW50 - intact:EBI-4404035|uniprotkb:D4AA09|ensembl:ENSRNOP00000002502|ensembl:ENSRNOP00000068621 - psi-mi:a4gw50_rat(display_long)|uniprotkb:Stk38l(gene name)|psi-mi:Stk38l(display_short)|uniprotkb:rCG_29601(orf name) - psi-mi:"MI:0424"(protein kinase assay) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4404069|imex:IM-17198-13 - - psi-mi:"MI:0898"(putative self) - psi-mi:"MI:0898"(putative self) - psi-mi:"MI:0326"(protein) - rgd:1564793|refseq:NP_001076805.1|refseq:XP_017448391.1|ensembl:ENSRNOG00000001828(gene)|ensembl:ENSRNOT00000002502(transcript)|ensembl:ENSRNOT00000086813(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051128"(regulation of cellular component organization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892 - go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity) - - figure legend:4b|resulting-ptm:"Autophosphorylation of stk38l (NDR2)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/08/31 2014/10/16 rogid:CvCno16gHKhQa85EaskK8UJGwWI10116 - intact-crc:FCE2F0F024569358 false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0833"(autoradiography) - uniprotkb:Q91VJ4 uniprotkb:Q13043 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4404116|imex:IM-17198-12 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity) - - figure legend:6c|resulting-ptm:"Autophosphorylation of STK38 (NDR1)"|comment:Stk38 is kinase-dead.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/08/31 2014/10/16 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 intact-crc:B550A8C5AA9C18E6|rigid:CU/2zqbde9lmn1QlKMhN7TWKei8 false ha tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q13043 - intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 - psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) - psi-mi:"MI:0424"(protein kinase assay) Zhou et al. (2011) pubmed:21730291|imex:IM-17198 taxid:9606(human)|taxid:9606(Homo sapiens) - psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4404078|imex:IM-17198-14 - - psi-mi:"MI:0898"(putative self) - psi-mi:"MI:0898"(putative self) - psi-mi:"MI:0326"(protein) - ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N - go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity) - - figure legend:6c|resulting-ptm:"Autophosphorylation of stk4 (MST1)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/08/31 2014/10/16 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 - intact-crc:EA0ECAD8F396406C false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0833"(autoradiography) -