#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9WVE0 uniprotkb:P48316 intact:EBI-3835567|ensembl:ENSMUSP00000040524 intact:EBI-4394230|ensembl:ENSMUSP00000044034 psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:ga45a_mouse(display_long)|uniprotkb:Gadd45a(gene name)|psi-mi:Gadd45a(display_short)|uniprotkb:Ddit1(gene name synonym)|uniprotkb:Gadd45(gene name synonym)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4394246|imex:IM-16563-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus) refseq:NP_031862.1|ensembl:ENSMUSG00000036390(gene)|ensembl:ENSMUST00000043098(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|reactome:R-MMU-6804114 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6F|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-p19)|taxid:10090(Mus musculus embryonic teratocarcinoma cell line, epithelial-like, induced by retinoic acid) - 2011/08/03 2014/10/16 rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090 rogid:SVeihu3cCuOXE4SFl8CB2A8XEwE10090 intact-crc:F885E9BC164AE2B4|rigid:YrwjkepFUubhorRNFrrkIq8EcTE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WVE0 uniprotkb:P56581 intact:EBI-3835567|ensembl:ENSMUSP00000040524 intact:EBI-4320525|uniprotkb:Q3TPW4|uniprotkb:Q542A9|uniprotkb:Q5U3M4|uniprotkb:Q5U3M5|uniprotkb:Q6PJW4|uniprotkb:Q8BPK0|ensembl:ENSMUSP00000121000 psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:tdg_mouse(display_long)|uniprotkb:Tdg(gene name)|psi-mi:Tdg(display_short)|uniprotkb:C-JUN leucine zipper interactive protein JZA-3(gene name synonym)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4394246|imex:IM-16563-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus) refseq:NP_035691.2|refseq:NP_766140.2|ensembl:ENSMUSG00000034674(gene)|ensembl:ENSMUST00000151390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0016605"(PML body)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|reactome:R-MMU-110329|reactome:R-MMU-110357|reactome:R-MMU-3108214|reactome:R-MMU-5221030|go:"GO:0003677"(DNA binding)|dip:DIP-216N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6F|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-p19)|taxid:10090(Mus musculus embryonic teratocarcinoma cell line, epithelial-like, induced by retinoic acid) - 2011/08/03 2014/10/16 rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090 rogid:zR76gYnkGSSFMFlHrLeYV5zuxz810090 intact-crc:F885E9BC164AE2B4|rigid:YrwjkepFUubhorRNFrrkIq8EcTE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P24522 uniprotkb:Q9GZX7 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335 psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320710|imex:IM-16563-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6D|comment:Cells do not express endogenous TDG.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u251)|taxid:9606(Homo sapiens) - 2011/08/03 2014/10/16 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606 intact-crc:3CBE8AE57A06948D|rigid:HpFbckMupbuVCyigVWjVqe95oak false myc tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9GZX7 uniprotkb:Q13569 intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335 intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3 psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320708|imex:IM-16563-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1 ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6D|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u251)|taxid:9606(Homo sapiens) - 2011/08/03 2014/10/16 rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606 rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606 intact-crc:D191115A092223CB|rigid:khegyOU4qH7m00MjYmfFIRqzUUk false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9GZX7 uniprotkb:P24522 intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320708|imex:IM-16563-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1 refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6D|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u251)|taxid:9606(Homo sapiens) - 2011/08/03 2014/10/16 rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 intact-crc:D191115A092223CB|rigid:khegyOU4qH7m00MjYmfFIRqzUUk false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) ensembl:ENSMUSG00000046402 uniprotkb:P56581 intact:EBI-4320506 intact:EBI-4320525|uniprotkb:Q3TPW4|uniprotkb:Q542A9|uniprotkb:Q5U3M4|uniprotkb:Q5U3M5|uniprotkb:Q6PJW4|uniprotkb:Q8BPK0|ensembl:ENSMUSP00000121000 psi-mi:ret1_mouse_gene(display_short)|psi-mi:ENSMUSG00000046402(display_long) psi-mi:tdg_mouse(display_long)|uniprotkb:Tdg(gene name)|psi-mi:Tdg(display_short)|uniprotkb:C-JUN leucine zipper interactive protein JZA-3(gene name synonym)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320524|imex:IM-16563-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_035691.2|refseq:NP_766140.2|ensembl:ENSMUSG00000034674(gene)|ensembl:ENSMUST00000151390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0016605"(PML body)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|reactome:R-MMU-110329|reactome:R-MMU-110357|reactome:R-MMU-3108214|reactome:R-MMU-5221030|go:"GO:0003677"(DNA binding)|dip:DIP-216N - - - figure legend:Fig. 2D|comment:TDG binds directly to the promoter of Ret1|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2011/08/03 2014/10/16 - rogid:zR76gYnkGSSFMFlHrLeYV5zuxz810090 intact-crc:88F234B8A54AFDC8 false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:P56581 ensembl:ENSMUSG00000004885 intact:EBI-4320525|uniprotkb:Q3TPW4|uniprotkb:Q542A9|uniprotkb:Q5U3M4|uniprotkb:Q5U3M5|uniprotkb:Q6PJW4|uniprotkb:Q8BPK0|ensembl:ENSMUSP00000121000 intact:EBI-4320504 psi-mi:tdg_mouse(display_long)|uniprotkb:Tdg(gene name)|psi-mi:Tdg(display_short)|uniprotkb:C-JUN leucine zipper interactive protein JZA-3(gene name synonym)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:rabp2_mouse_gene(display_short)|psi-mi:ENSMUSG00000004885(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320542|imex:IM-16563-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_035691.2|refseq:NP_766140.2|ensembl:ENSMUSG00000034674(gene)|ensembl:ENSMUST00000151390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0016605"(PML body)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|reactome:R-MMU-110329|reactome:R-MMU-110357|reactome:R-MMU-3108214|reactome:R-MMU-5221030|go:"GO:0003677"(DNA binding)|dip:DIP-216N - - - - figure legend:Fig. 2D|comment:TDG binds directly to the promoter of Rabp2.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2011/08/03 2014/10/16 rogid:zR76gYnkGSSFMFlHrLeYV5zuxz810090 - intact-crc:68E7D684190EA77B false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000046402 uniprotkb:B2RWS6 intact:EBI-4320506 intact:EBI-3953360|ensembl:ENSMUSP00000066789|uniprotkb:E9PYJ8 psi-mi:ret1_mouse_gene(display_short)|psi-mi:ENSMUSG00000046402(display_long) psi-mi:ep300_mouse(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:Ep300(gene name)|psi-mi:Ep300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4373543|imex:IM-16563-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003823"(antigen binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000055024(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|ensembl:ENSMUST00000068387(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0009749"(response to glucose)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010560"(positive regulation of glycoprotein biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031325"(positive regulation of cellular metabolic process)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036268"(swimming)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031324"(negative regulation of cellular metabolic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0140067"(peptidyl-lysine butyrylation)|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000629"(negative regulation of miRNA metabolic process)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-3899300|reactome:R-MMU-5250924|reactome:R-MMU-5621575|reactome:R-MMU-5689901|reactome:R-MMU-6781823|reactome:R-MMU-6782210|reactome:R-MMU-6804758|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-8866907|reactome:R-MMU-8936459|reactome:R-MMU-8939243|reactome:R-MMU-8941856|reactome:R-MMU-8941858|reactome:R-MMU-8951936|reactome:R-MMU-9018519|reactome:R-MMU-9029569|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-6782135|refseq:NP_808489.4|dip:DIP-60610N - - - figure legend:Fig. 2D|comment:Recruitment of ep300 to Ret1 is dependent of the binding of TDG.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2011/08/03 2014/10/16 - rogid:+i8zWNbBTzr6QvuKBIIPiIDIxQg10090 intact-crc:3157BA85BC98515D false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000004885 uniprotkb:B2RWS6 intact:EBI-4320504 intact:EBI-3953360|ensembl:ENSMUSP00000066789|uniprotkb:E9PYJ8 psi-mi:rabp2_mouse_gene(display_short)|psi-mi:ENSMUSG00000004885(display_long) psi-mi:ep300_mouse(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:Ep300(gene name)|psi-mi:Ep300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4373548|imex:IM-16563-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003823"(antigen binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000055024(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|ensembl:ENSMUST00000068387(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0009749"(response to glucose)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010560"(positive regulation of glycoprotein biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031325"(positive regulation of cellular metabolic process)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036268"(swimming)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031324"(negative regulation of cellular metabolic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0140067"(peptidyl-lysine butyrylation)|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000629"(negative regulation of miRNA metabolic process)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-3899300|reactome:R-MMU-5250924|reactome:R-MMU-5621575|reactome:R-MMU-5689901|reactome:R-MMU-6781823|reactome:R-MMU-6782210|reactome:R-MMU-6804758|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-8866907|reactome:R-MMU-8936459|reactome:R-MMU-8939243|reactome:R-MMU-8941856|reactome:R-MMU-8941858|reactome:R-MMU-8951936|reactome:R-MMU-9018519|reactome:R-MMU-9029569|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-6782135|refseq:NP_808489.4|dip:DIP-60610N - - - figure legend:Fig. 2D|comment:Recruitment of ep300 to Rabp2 is dependent of the binding of TDG.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2011/08/03 2014/10/16 - rogid:+i8zWNbBTzr6QvuKBIIPiIDIxQg10090 intact-crc:3B4EB155D7065131 false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:P24522 uniprotkb:Q9GZX7 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335 psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320634|imex:IM-16563-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/03 2014/10/16 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606 intact-crc:2EA0A138488D165B|rigid:HpFbckMupbuVCyigVWjVqe95oak false myc tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9GZX7 uniprotkb:Q13569 intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335 intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3 psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320570|imex:IM-16563-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1 ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/03 2014/10/16 rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606 rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606 intact-crc:8B147DA5FBDB060F|rigid:OoUzLEfKinB2gKSKqwDZ1FN61UA false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P24522 uniprotkb:Q13569 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3 psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320600|imex:IM-16563-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/03 2014/10/16 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606 intact-crc:1B29D22F8A6CD387|rigid:hLxLBnZvJ6BUpAksURCGR7lohoM false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13569 uniprotkb:Q9GZX7 intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3 intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335 psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320642|imex:IM-16563-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/03 2014/10/16 rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606 rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606 intact-crc:9ACA7462FE8B307A|rigid:OoUzLEfKinB2gKSKqwDZ1FN61UA false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P24522 uniprotkb:Q13569 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3 psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320650|imex:IM-16563-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/03 2014/10/16 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606 intact-crc:26E09C00D9A830D0|rigid:hLxLBnZvJ6BUpAksURCGR7lohoM false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9GZX7 uniprotkb:Q13569 intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335 intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3 psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320620|imex:IM-16563-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1 ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/03 2014/10/16 rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606 rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606 intact-crc:B79CE3034FFB67F1|rigid:OoUzLEfKinB2gKSKqwDZ1FN61UA false flag tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13569 uniprotkb:P24522 intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320618|imex:IM-16563-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/03 2014/10/16 rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 intact-crc:EC4FD08752A695B1|rigid:hLxLBnZvJ6BUpAksURCGR7lohoM false - flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9GZX7 uniprotkb:Q13569 intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335 intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3 psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320679|imex:IM-16563-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1 ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6D|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2011/08/03 2014/10/16 rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606 rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606 intact-crc:A752C58346B7928D|rigid:khegyOU4qH7m00MjYmfFIRqzUUk false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9GZX7 uniprotkb:P24522 intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320679|imex:IM-16563-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1 refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6D|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2011/08/03 2014/10/16 rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 intact-crc:A752C58346B7928D|rigid:khegyOU4qH7m00MjYmfFIRqzUUk false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9GZX7 uniprotkb:P24522 intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym) psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cortellino et al. (2011) pubmed:21722948|imex:IM-16563 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320690|imex:IM-16563-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1 refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6D|comment:Cells do not express endogenous TDG.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2011/08/03 2014/10/16 rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 intact-crc:8BA627640194A396|rigid:HpFbckMupbuVCyigVWjVqe95oak false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)