#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P35561	uniprotkb:P35561	intact:EBI-703793|ensembl:ENSMUSP00000037192	intact:EBI-703793|ensembl:ENSMUSP00000037192	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4318867|imex:IM-16554-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	go:"GO:0005794"(Golgi apparatus)	-	-	figure legend:Supp. Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2011/08/02	2014/10/16	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	intact-crc:555C30BBEDEF22EB|rigid:FqJe12RU71e13XefqMHluf/heL8	false	ha tag:?-?|sufficient binding region:62-428|mutation disrupting interaction:314-315	sufficient binding region:1-65|green fluorescent protein tag:n-n|mutation decreasing interaction:44-44,46-46	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:P35561	intact:EBI-4319122	intact:EBI-703793|ensembl:ENSMUSP00000037192	-	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:ap1g1_cerae_protein(display_short)|psi-mi:EBI-4319122(display_long)	psi-mi:"MI:0663"(confocal microscopy)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4374403|imex:IM-16554-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	-	go:"GO:0005802"(trans-Golgi network)	-	comment:Similar to P22892	figure legend:Figs. 6F, 6G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2011/08/02	2014/10/16	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	-	intact-crc:9152E87F770B2CF1	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:P35561	uniprotkb:P35561	intact:EBI-703793|ensembl:ENSMUSP00000037192	intact:EBI-703793|ensembl:ENSMUSP00000037192	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4318851|imex:IM-16554-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	go:"GO:0005794"(Golgi apparatus)	-	-	figure legend:Supp. Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2011/08/02	2014/10/16	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	intact-crc:EB7181C82B5C8C59|rigid:FqJe12RU71e13XefqMHluf/heL8	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:P35561	uniprotkb:P35561	intact:EBI-703793|ensembl:ENSMUSP00000037192	intact:EBI-703793|ensembl:ENSMUSP00000037192	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4318891|imex:IM-16554-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2011/08/02	2014/10/16	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	intact-crc:4444ABE37A9F8916|rigid:FqJe12RU71e13XefqMHluf/heL8	false	glutathione s tranferase tag:?-?|sufficient binding region:1-65	ha tag:?-?|sufficient binding region:189-428	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35561	uniprotkb:P35561	intact:EBI-703793|ensembl:ENSMUSP00000037192	intact:EBI-703793|ensembl:ENSMUSP00000037192	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4318836|imex:IM-16554-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2011/08/02	2014/10/16	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	intact-crc:761C44B35327F902|rigid:FqJe12RU71e13XefqMHluf/heL8	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
intact:EBI-4319122	uniprotkb:P35561	-	intact:EBI-703793|ensembl:ENSMUSP00000037192	psi-mi:ap1g1_cerae_protein(display_short)|psi-mi:EBI-4319122(display_long)	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4319124|imex:IM-16554-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	psi-mi:"MI:0469"(intact)	comment:Similar to P22892	-	figure legend:Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2011/08/02	2014/10/16	-	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	intact-crc:DA5290A66FD63A27	false	-	necessary binding region:314-315|ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35561	uniprotkb:Q792I0	intact:EBI-703793|ensembl:ENSMUSP00000037192	intact:EBI-704626|ensembl:ENSRNOP00000065941	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:lin7c_rat(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:Lin7c(gene name)|psi-mi:Lin7c(display_short)|uniprotkb:Mals3(gene name synonym)|uniprotkb:Veli3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4319026|imex:IM-16554-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	rgd:621164|refseq:NP_068623.1|ensembl:ENSRNOG00000045698(gene)|ensembl:ENSRNOT00000073258(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6B|comment:Deletion of residues 314-315 abrogated AP1 binding without altering interaction with Lin-7, CASK, or Filamin A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/08/02	2014/10/16	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	rogid:F2rasaJ64Olc9qScN79LJRqsUEE10116	intact-crc:6E55C92D6BC5BDE5|rigid:Y4wU1YnPL+Fzz2LSwxOIIGHsTW0	false	sufficient binding region:179..179-428,1-81..81|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35561	uniprotkb:Q62915	intact:EBI-703793|ensembl:ENSMUSP00000037192	intact:EBI-704635	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:cskp_rat(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short)	psi-mi:"MI:0096"(pull down)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4319026|imex:IM-16554-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	rgd:62004|refseq:NP_071520.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|rcsb pdb:1RSO|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|reactome:R-RNO-6794361|rcsb pdb:6LNM|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6B|comment:Deletion of residues 314-315 abrogated AP1 binding without altering interaction with Lin-7, CASK, or Filamin A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/08/02	2014/10/16	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	rogid:S7T42QMExgUKMZpBQEJNjQeR9ZE10116	intact-crc:6E55C92D6BC5BDE5|rigid:Y4wU1YnPL+Fzz2LSwxOIIGHsTW0	false	sufficient binding region:179..179-428,1-81..81|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35561	uniprotkb:C0JPT7	intact:EBI-703793|ensembl:ENSMUSP00000037192	intact:EBI-4318987|ensembl:ENSRNOP00000070703	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:c0jpt7_rat(display_long)|uniprotkb:Flna(gene name)|psi-mi:Flna(display_short)|uniprotkb:Flna_predicted(gene name synonym)|uniprotkb:rCG_43821(orf name)	psi-mi:"MI:0096"(pull down)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4319026|imex:IM-16554-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	rgd:1560614|refseq:NP_001128071.1|refseq:XP_006229632.1|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|ensembl:ENSRNOG00000054890(gene)|ensembl:ENSRNOT00000079889(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-RNO-114608|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|reactome:R-RNO-430116|reactome:R-RNO-446353|reactome:R-RNO-5627123	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6B|comment:Deletion of residues 314-315 abrogated AP1 binding without altering interaction with Lin-7, CASK, or Filamin A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/08/02	2014/10/16	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	rogid:C/PtCOXLaBiFq1JySyQSz/U9yyw10116	intact-crc:6E55C92D6BC5BDE5|rigid:Y4wU1YnPL+Fzz2LSwxOIIGHsTW0	false	sufficient binding region:179..179-428,1-81..81|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35561	uniprotkb:B2RYN6	intact:EBI-703793|ensembl:ENSMUSP00000037192	intact:EBI-4319005	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:b2ryn6_rat(display_long)|uniprotkb:Ap1g1(gene name)|psi-mi:Ap1g1(display_short)|uniprotkb:rCG_51678(orf name)	psi-mi:"MI:0096"(pull down)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4319026|imex:IM-16554-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	refseq:NP_604455.1|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|rgd:619785|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005518"(collagen binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0019894"(kinesin binding)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0098793"(presynapse)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6B|comment:Deletion of residues 314-315 abrogated AP1 binding without altering interaction with Lin-7, CASK, or Filamin A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/08/02	2014/10/16	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	rogid:uc70MdCStso/6h91OQOITtSyNKE10116	intact-crc:6E55C92D6BC5BDE5|rigid:Y4wU1YnPL+Fzz2LSwxOIIGHsTW0	false	sufficient binding region:179..179-428,1-81..81|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2RYN6	uniprotkb:P35561	intact:EBI-4319005	intact:EBI-703793|ensembl:ENSMUSP00000037192	psi-mi:b2ryn6_rat(display_long)|uniprotkb:Ap1g1(gene name)|psi-mi:Ap1g1(display_short)|uniprotkb:rCG_51678(orf name)	psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ma et al. (2011)	pubmed:21703452|imex:IM-16554	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4319050|imex:IM-16554-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_604455.1|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|rgd:619785|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005518"(collagen binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0019894"(kinesin binding)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0098793"(presynapse)	refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/08/02	2014/10/16	rogid:uc70MdCStso/6h91OQOITtSyNKE10116	rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090	intact-crc:664C08C759D8CB09|rigid:MybKURrjlbMfx87TDd9dIwBJ5nw	false	-	mutation disrupting interaction:320-320|sufficient binding region:179..179-428,1-81..81|glutathione s tranferase tag:?-?|necessary binding region:314-315|mutation disrupting interaction:319-319|mutation disrupting interaction:322-322	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)