#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NQG6 uniprotkb:O14925 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-1047996|uniprotkb:Q53FF8|uniprotkb:Q6P5S5|uniprotkb:Q5T1E6|ensembl:ENSP00000464522 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:tim23_human(display_long)|uniprotkb:TIMM23(gene name)|psi-mi:TIMM23(display_short)|uniprotkb:TIM23(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6993550|mint:MINT-8212736|imex:IM-16261-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212738(identity) refseq:NP_006318.1|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005681(Mitochondrial import inner membrane translocase, subunit Tim23)|mint:O14925|reactome:R-HSA-1268020|ensembl:ENSG00000265354(gene)|ensembl:ENST00000580018(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|mint:MINT-8212739(identity) go:"GO:0005741"(mitochondrial outer membrane) - - comment:homomint|comment:mint|figure legend:f1f f1g f1h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:Hmu/kwfaPLGFGYBJH0oue7JDYqM9606 intact-crc:86C08A5801713AAE|rigid:ApKh2M12bf1Sq70p6YtSmrG+YlM false v5 tag:?-?(MINT-8212743) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NQG6 uniprotkb:Q15388 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-711636|uniprotkb:A8K195|uniprotkb:Q498B3|uniprotkb:Q6IBT4|ensembl:ENSP00000355566 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:tom20_human(display_long)|uniprotkb:Outer mitochondrial membrane receptor Tom20(gene name synonym)|uniprotkb:TOMM20(gene name)|psi-mi:TOMM20(display_short)|uniprotkb:KIAA0016(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6993550|mint:MINT-8212736|imex:IM-16261-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212738(identity) refseq:NP_055580.1|dip:DIP-46735N|ensembl:ENSG00000173726(gene)|ensembl:ENST00000366607(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905242"(response to 3,3',5-triiodo-L-thyronine)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR022422|interpro:IPR023392|rcsb pdb:4APO|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|mint:MINT-8212777(identity) go:"GO:0005741"(mitochondrial outer membrane) - - comment:homomint|comment:mint|figure legend:f1f f1g f1h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:+wNh1qTU0NtgQekYJjhfj6O3UoA9606 intact-crc:86C08A5801713AAE|rigid:ApKh2M12bf1Sq70p6YtSmrG+YlM false v5 tag:?-?(MINT-8212743) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NQG6 uniprotkb:Q9NQG6 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6993594|mint:MINT-8212755|imex:IM-16261-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212758(identity) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212758(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" comment:mint|figure legend:f3h f3k|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 intact-crc:D01458B65F8AC6D3|rigid:3h0uPIQAbYks/9M0HEHkZIv1SG0 false binding-associated region:49-195(MINT-8212772)|v5 tag:?-?(MINT-8212759) binding-associated region:49-195(MINT-8212772)|v5 tag:?-?(MINT-8212759) 2 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O00429 uniprotkb:O00429 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6993609|mint:MINT-8212999|imex:IM-16261-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8213001(identity) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8213007(identity) - crc64:F9521A376B785B71 crc64:F9521A376B785B71 figure legend:f7e|comment:homomint|comment:mint|comment:Drp1 forms oligomers|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 intact-crc:76F60D00BBA3BF58|rigid:7PC0C/lIptSW1S/MkFiH+lo+D2E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NQG6 uniprotkb:Q9NQG6 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6993649|mint:MINT-8212789|imex:IM-16261-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212791(identity) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212798(identity) - - - comment:homomint|comment:mint|figure legend:f3i|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 intact-crc:184D1B2524240722|rigid:di5g0UMYeyBhFaWDHtrCP6tCVKE false v5 tag:?-?(MINT-8212794) ha tag:?-?(MINT-8212800) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NQG6 uniprotkb:O00429 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6993684|mint:MINT-8212806|imex:IM-16261-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212808(identity) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8212812(identity) - - crc64:F9521A376B785B71 comment:homomint|comment:mint|figure legend:f4d f6a f8b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 intact-crc:BEE6E8D7CB34B1C1|rigid:T2OvvVot46treLPJe7t9p0Mi8fw false v5 tag:?-?(MINT-8212809)|mutation disrupting interaction:160-169(MINT-8212877) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NQG6 uniprotkb:O00429 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6993703|mint:MINT-8212819|imex:IM-16261-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212821(identity) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8212825(identity) - - crc64:F9521A376B785B71 figure legend:f5f|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 intact-crc:BC2AE870B70840AF|rigid:T2OvvVot46treLPJe7t9p0Mi8fw false v5 tag:?-?(MINT-8212822) ha tag:?-?(MINT-8212829)|mutation disrupting interaction:38-38(MINT-8212831) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NQG6 uniprotkb:O00429 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6993725|mint:MINT-8212881|imex:IM-16261-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212883(identity) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8212889(identity) - - crc64:F9521A376B785B71 comment:homomint|comment:mint|figure legend:f4d f6a f8b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 intact-crc:2590CFB3BEE75104|rigid:T2OvvVot46treLPJe7t9p0Mi8fw false mutation decreasing interaction:431-463(MINT-8212884)|v5 tag:?-?(MINT-8212886) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NQG6 uniprotkb:Q9Y3D6 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-3385283|ensembl:ENSP00000223136|uniprotkb:Q9BTP3 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:fis1_human(display_long)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:TTC11(gene name synonym)|uniprotkb:FIS1 homolog(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 11(gene name synonym)|uniprotkb:CGI-135(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-6993764|mint:MINT-8212925|imex:IM-16261-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212927(identity) ensembl:ENSG00000214253(gene)|ensembl:ENST00000223136(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902617"(response to fluoride)|go:"GO:1903579"(negative regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000192"(negative regulation of fatty acid transport)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|mint:Q9Y3D6|rcsb pdb:1NZN|rcsb pdb:1PC2|reactome:R-HSA-9603798|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|refseq:NP_057152.2|mint:MINT-8212938(identity) - - - comment:homomint|comment:mint|figure legend:f8b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:5YzrFokAQLKvMCqzS12qalQtu489606 intact-crc:08B4D4BA5AE82F08|rigid:zNpq1u3LV2s90ZHHolGo5/ksWho false v5 tag:?-?(MINT-8212930) myc tag:?-?(MINT-8293132) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NQG6 uniprotkb:O00429 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-6993764|mint:MINT-8212925|imex:IM-16261-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212927(identity) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8212933(identity) - - crc64:F9521A376B785B71 comment:homomint|comment:mint|figure legend:f8b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 intact-crc:08B4D4BA5AE82F08|rigid:zNpq1u3LV2s90ZHHolGo5/ksWho false v5 tag:?-?(MINT-8212930) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NQG6 uniprotkb:O00429 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6993744|mint:MINT-8212912|imex:IM-16261-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212914(identity) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8212920(identity) - - crc64:F9521A376B785B71 comment:homomint|comment:mint|figure legend:f8b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 intact-crc:325E67CED0A5A009|rigid:T2OvvVot46treLPJe7t9p0Mi8fw false v5 tag:?-?(MINT-8212917)|mutation disrupting interaction:1-48(MINT-8212915) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y3D6 uniprotkb:Q9NQG6 intact:EBI-3385283|ensembl:ENSP00000223136|uniprotkb:Q9BTP3 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 psi-mi:fis1_human(display_long)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:TTC11(gene name synonym)|uniprotkb:FIS1 homolog(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 11(gene name synonym)|uniprotkb:CGI-135(orf name) psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6993803|mint:MINT-8212968|imex:IM-16261-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000214253(gene)|ensembl:ENST00000223136(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902617"(response to fluoride)|go:"GO:1903579"(negative regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000192"(negative regulation of fatty acid transport)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|mint:Q9Y3D6|rcsb pdb:1NZN|rcsb pdb:1PC2|reactome:R-HSA-9603798|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|refseq:NP_057152.2|mint:MINT-8212974(identity) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212970(identity) - - - comment:homomint|comment:mint|figure legend:f8c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:5YzrFokAQLKvMCqzS12qalQtu489606 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 intact-crc:E046D11A3B58E69C|rigid:oMwmcjYsj7MWyyzTuJ911Gomlvg false myc tag:?-?(MINT-8212975) v5 tag:?-?(MINT-8212971) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NQG6 uniprotkb:Q9Y3D6 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-3385283|ensembl:ENSP00000223136|uniprotkb:Q9BTP3 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:fis1_human(display_long)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:TTC11(gene name synonym)|uniprotkb:FIS1 homolog(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 11(gene name synonym)|uniprotkb:CGI-135(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6993785|mint:MINT-8212955|imex:IM-16261-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212957(identity) ensembl:ENSG00000214253(gene)|ensembl:ENST00000223136(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902617"(response to fluoride)|go:"GO:1903579"(negative regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000192"(negative regulation of fatty acid transport)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|mint:Q9Y3D6|rcsb pdb:1NZN|rcsb pdb:1PC2|reactome:R-HSA-9603798|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|refseq:NP_057152.2|mint:MINT-8212961(identity) - - - comment:homomint|comment:mint|figure legend:f8a f8b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:5YzrFokAQLKvMCqzS12qalQtu489606 intact-crc:42933274B5300100|rigid:oMwmcjYsj7MWyyzTuJ911Gomlvg false v5 tag:?-?(MINT-8212958) myc tag:?-?(MINT-8212964) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O00429 uniprotkb:Q9NQG6 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6993837|mint:MINT-8212983|imex:IM-16261-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8212991(identity) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212985(identity) - crc64:F9521A376B785B71 - comment:homomint|comment:mint|figure legend:sf4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 intact-crc:8C6133543EB30085|rigid:T2OvvVot46treLPJe7t9p0Mi8fw false myc tag:?-?(MINT-8212996) v5 tag:?-?(MINT-8212986) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O00429 uniprotkb:Q9NQG6 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6994040|mint:MINT-8293107|imex:IM-16261-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8293114(identity) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8293110(identity) go:"GO:0005739"(mitochondrion) crc64:F9521A376B785B71 - figure legend:f4c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 intact-crc:1C72E2D3F779F43C|rigid:T2OvvVot46treLPJe7t9p0Mi8fw false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O00429 uniprotkb:Q9NQG6 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6994001|mint:MINT-8212834|imex:IM-16261-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8212840(identity) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212836(identity) go:"GO:0005739"(mitochondrion) crc64:F9521A376B785B71 - comment:homomint|comment:mint|figure legend:sf3 f6d f4a f5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 intact-crc:22D850610E8B33B7|rigid:T2OvvVot46treLPJe7t9p0Mi8fw false - v5 tag:?-?(MINT-8212837)|mutation disrupting interaction:1-48(MINT-8212851) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9NQG6 uniprotkb:O00429 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6994021|mint:MINT-8212858|imex:IM-16261-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8212861(identity) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N|mint:MINT-8212867(identity) go:"GO:0005739"(mitochondrion) - crc64:F9521A376B785B71 figure legend:f4b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 intact-crc:9F1130006AC7521E|rigid:T2OvvVot46treLPJe7t9p0Mi8fw false v5 tag:?-?(MINT-8212864) ha tag:?-?(MINT-8212872) - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9Y3D6 uniprotkb:Q9NQG6 intact:EBI-3385283|ensembl:ENSP00000223136|uniprotkb:Q9BTP3 intact:EBI-740987|ensembl:ENSP00000327124|ensembl:ENSP00000385191|uniprotkb:Q9BUI3|uniprotkb:Q7L890 psi-mi:fis1_human(display_long)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:TTC11(gene name synonym)|uniprotkb:FIS1 homolog(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 11(gene name synonym)|uniprotkb:CGI-135(orf name) psi-mi:mid51_human(display_long)|uniprotkb:MIEF1(gene name)|psi-mi:MIEF1(display_short)|uniprotkb:MID51(gene name synonym)|uniprotkb:Mitochondrial elongation factor 1(gene name synonym)|uniprotkb:SMCR7L(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 51 kDa(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Zhao et al. (2011) pubmed:21701560|imex:IM-16261|mint:MINT-8212727|doi:10.1038/emboj.2011.198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6994053|mint:MINT-8293136|imex:IM-16261-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000214253(gene)|ensembl:ENST00000223136(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902617"(response to fluoride)|go:"GO:1903579"(negative regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000192"(negative regulation of fatty acid transport)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|mint:Q9Y3D6|rcsb pdb:1NZN|rcsb pdb:1PC2|reactome:R-HSA-9603798|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|refseq:NP_057152.2|mint:MINT-8293142(identity) refseq:NP_061881.2|rcsb pdb:5X9B|rcsb pdb:5X9C|rcsb pdb:4NXX|rcsb pdb:4NXT|rcsb pdb:4NXU|rcsb pdb:4NXV|ensembl:ENSG00000100335(gene)|ensembl:ENST00000325301(transcript)|ensembl:ENST00000404569(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:4NXW|refseq:XP_016884327.1|refseq:NP_001291493.1|refseq:XP_011528538.1|refseq:XP_011528539.1|refseq:XP_011528540.1|mint:MINT-8293138(identity) go:"GO:0005739"(mitochondrion) - - comment:homomint|comment:mint|figure legend:f8g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/10/06 2014/10/16 rogid:5YzrFokAQLKvMCqzS12qalQtu489606 rogid:w9n3VA1Bnf/aABCbUaypoysRkVc9606 intact-crc:10D9D75074E79360|rigid:oMwmcjYsj7MWyyzTuJ911Gomlvg false myc tag:?-?(MINT-8293143) v5 tag:?-?(MINT-8293139) - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)