#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q95KM6	uniprotkb:O97758	intact:EBI-6988362|ensembl:ENSCAFP00030035927|intact:MINT-8184441	intact:EBI-6988333|intact:MINT-1778189	psi-mi:cld2_canlf(display_long)|uniprotkb:CLDN2(gene name)|psi-mi:CLDN2(display_short)	psi-mi:zo1_canlf(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Maher et al. (2011)	pubmed:21689651|imex:IM-16747|mint:MINT-8184456|doi:10.1016/j.febslet.2011.05.060	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-6988379|mint:MINT-8184465|imex:IM-16747-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCAFG00030022406(gene)|ensembl:ENSCAFT00030041176(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0042802"(identical protein binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR005411(Claudin-2)|interpro:IPR006187(Claudin)|interpro:IPR017974|refseq:NP_001003089.1|mint:MINT-8184469(identity)|uniprotkb:Q95KM6(original identifier)	interpro:IPR035597|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0009986"(cell surface)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|refseq:NP_001003140.1|mint:O97758|interpro:IPR036028|interpro:IPR036034|mint:MINT-8184466(identity)|uniprotkb:O97758(original identifier)	go:"GO:0005923"(bicellular tight junction)	comment:mint	comment:mint|function:The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions	figure legend:F2B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2011/05/30	2014/10/16	rogid:tdz+uO6O26Da7tyoLK4crqPiy1A9615	rogid:ahJn9QpY395wArDFwZ2FwDxf6s89615	intact-crc:8185BB31D8888F78|rigid:aKj3piCdi/DENc53cbU+2+gLaCo	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9D563	uniprotkb:O97758	intact:EBI-6988402|ensembl:ENSMUSP00000023400|intact:MINT-8085693	intact:EBI-6988333|intact:MINT-1778189	psi-mi:tm114_mouse(display_long)|uniprotkb:Claudin-26(gene name synonym)|uniprotkb:Cldn26(gene name synonym)|uniprotkb:Tmem114(gene name)|psi-mi:Tmem114(display_short)	psi-mi:zo1_canlf(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Maher et al. (2011)	pubmed:21689651|imex:IM-16747|mint:MINT-8184456|doi:10.1016/j.febslet.2011.05.060	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-6988395|mint:MINT-8184472|imex:IM-16747-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000022715(gene)|ensembl:ENSMUST00000023400(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR039951|refseq:NP_083346.1|mint:MINT-8184476(identity)|uniprotkb:Q9D563(original identifier)	interpro:IPR035597|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0009986"(cell surface)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|refseq:NP_001003140.1|mint:O97758|interpro:IPR036028|interpro:IPR036034|mint:MINT-8184473(identity)|uniprotkb:O97758(original identifier)	go:"GO:0005886"(plasma membrane)	comment:mint	comment:mint|function:The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions	figure legend:F2B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2011/05/30	2014/10/16	rogid:zL1ABdiTZ1B4gbofVUFVnKPcapE10090	rogid:ahJn9QpY395wArDFwZ2FwDxf6s89615	intact-crc:5AFAD8A81A769A9C|rigid:QUz/BAEhN+UXTZ+Vaq20FCAvZEM	false	v5 tag:?-?(MINT-8184479)	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)