#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q07817-1	uniprotkb:P48558	intact:EBI-287195|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|intact:EBI-8058735|intact:MINT-89566|intact:EBI-8058554|intact:EBI-8058512|intact:EBI-8058443	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	psi-mi:q07817-1(display_long)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:Bcl-xL(isoform synonym)	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275391|imex:IM-15826-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78035(bclx_human)|ensembl:ENSG00000171552(gene)|ensembl:ENST00000678563(transcript)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	-	-	-	figure legend:2c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	intact-crc:05D2C8BC7382CE24|rigid:IWmZRTdxrQ3hkqjUJIN222DRnKo	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48558	uniprotkb:P07256	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-19922|uniprotkb:D6VPV3|ensemblfungi:YBL045C	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:qcr1_yeast(display_long)|uniprotkb:COR1(gene name)|psi-mi:COR1(display_short)|uniprotkb:QCR1(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c oxidoreductase core protein 1(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase 44 kDa protein(gene name synonym)|uniprotkb:YBL0403(orf name)|uniprotkb:YBL045C(locus name)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:Core protein I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275413|imex:IM-15826-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	refseq:NP_009508.1|sgd:S000000141|ensemblfungi:YBL045C(gene)|ensemblfungi:YBL045C_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022900"(electron transport chain)|go:"GO:0046872"(metal ion binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|rcsb pdb:1EZV|rcsb pdb:1KB9|rcsb pdb:1KYO|rcsb pdb:1P84|rcsb pdb:2IBZ|rcsb pdb:3CX5|rcsb pdb:3CXH|rcsb pdb:4PD4|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|reactome:R-SCE-611105|dip:DIP-2635N|mint:P07256	-	-	crc64:AE58739EFB695254	figure legend:table S1|agonist:H2O2 treatment was required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:fPEE0SQ86LRkL7Dco2tZ/6rPb4I559292	intact-crc:4D61B9DB8265C186|rigid:86lk6XAzT0hEecUK0aQ75TvmpgA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P23641	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-11178|uniprotkb:D6VWP7|ensemblfungi:YJR077C	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:mpcp_yeast(display_long)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:J1837(orf name)|uniprotkb:YJR077C(locus name)|uniprotkb:MIR1(gene name)|psi-mi:MIR1(display_short)|uniprotkb:mPic 1(gene name synonym)|uniprotkb:Mitochondrial import receptor(gene name synonym)|uniprotkb:p32(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275413|imex:IM-15826-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	ensemblfungi:YJR077C(gene)|ensemblfungi:YJR077C_mRNA(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|refseq:NP_012611.1|sgd:S000003838|dip:DIP-1714N	-	-	crc64:89D1D97C49A9E8F1	figure legend:table S1|agonist:H2O2 treatment was required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:kHmfGupxVg2OGqtJ1oIwqPCeY3Q559292	intact-crc:4D61B9DB8265C186|rigid:86lk6XAzT0hEecUK0aQ75TvmpgA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P07257	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-19929|uniprotkb:D6W4J1|ensemblfungi:YPR191W	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:qcr2_yeast(display_long)|uniprotkb:QCR2(gene name)|psi-mi:QCR2(display_short)|uniprotkb:Ubiquinol-cytochrome c oxidoreductase core protein 2(gene name synonym)|uniprotkb:P9677.6(orf name)|uniprotkb:YPR191W(locus name)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:COR2(gene name synonym)|uniprotkb:UCR2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275413|imex:IM-15826-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	refseq:NP_015517.1|sgd:S000006395|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0046872"(metal ion binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|rcsb pdb:1EZV|rcsb pdb:1KB9|rcsb pdb:1KYO|rcsb pdb:1P84|rcsb pdb:2IBZ|rcsb pdb:3CX5|rcsb pdb:3CXH|rcsb pdb:4PD4|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|ensemblfungi:YPR191W(gene)|ensemblfungi:YPR191W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|dip:DIP-3820N|mint:P07257	-	-	crc64:51FDE1C5DA4420D0	figure legend:table S1|agonist:H2O2 treatment was required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:KjarVU1IBv3BpBAuKqu+5dW7TbI559292	intact-crc:4D61B9DB8265C186|rigid:86lk6XAzT0hEecUK0aQ75TvmpgA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P04037	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-5039|uniprotkb:A2TBN6|uniprotkb:D6VTW7|ensemblfungi:YGL187C	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:cox4_yeast(display_long)|uniprotkb:COX4(gene name)|psi-mi:COX4(display_short)|uniprotkb:YGL187C(locus name)|uniprotkb:G1362(orf name)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275413|imex:IM-15826-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	refseq:NP_011328.1|sgd:S000003155|dip:DIP-2763N|mint:P04037|ensemblfungi:YGL187C(gene)|ensemblfungi:YGL187C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|rcsb pdb:1HR8|rcsb pdb:2ODX|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY	-	-	-	figure legend:table S1|agonist:H2O2 treatment was required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:BgFxxftKsM1hXTeVpOGK5ILmmvY559292	intact-crc:4D61B9DB8265C186|rigid:86lk6XAzT0hEecUK0aQ75TvmpgA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P50277	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-3632|uniprotkb:E9P967|uniprotkb:Q4R1J0|uniprotkb:D6W1N3|ensemblfungi:YNR058W	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:bioa_yeast(display_long)|uniprotkb:BIO3(gene name)|psi-mi:BIO3(display_short)|uniprotkb:YNR058W(locus name)|uniprotkb:N3510(orf name)|uniprotkb:Diaminopelargonic acid synthase(gene name synonym)|uniprotkb:7,8-diamino-pelargonic acid aminotransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275413|imex:IM-15826-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	refseq:NP_014456.1|sgd:S000005341|dip:DIP-4822N|mint:P50277|ensemblfungi:YNR058W(gene)|ensemblfungi:YNR058W_mRNA(transcript)|go:"GO:0004015"(adenosylmethionine-8-amino-7-oxononanoate transaminase activity)|go:"GO:0004141"(dethiobiotin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0009102"(biotin biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR005815(Adenosylmethionine--8-amino-7-oxononanoate aminotransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)	-	-	crc64:00A8BC42DCBED19A	figure legend:table S1|agonist:H2O2 treatment was required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:EaY1icGIW3Kv8zNebgFuB68GBgY559292	intact-crc:4D61B9DB8265C186|rigid:86lk6XAzT0hEecUK0aQ75TvmpgA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P00830	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-3242|uniprotkb:D6VWU0|ensemblfungi:YJR121W	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:atpb_yeast(display_long)|uniprotkb:ATP2(gene name)|psi-mi:ATP2(display_short)|uniprotkb:J2041(orf name)|uniprotkb:YJR121W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275413|imex:IM-15826-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	sgd:S000003882|refseq:NP_012655.3|dip:DIP-3028N|mint:P00830|ensemblfungi:YJR121W(gene)|ensemblfungi:YJR121W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613	-	-	crc64:EDFF256826F68F0C	figure legend:table S1|agonist:H2O2 treatment was required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:XA14lgBJ4D0nrBpMQw5tsc4aByU559292	intact-crc:4D61B9DB8265C186|rigid:86lk6XAzT0hEecUK0aQ75TvmpgA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P09435	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275413|imex:IM-15826-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129	-	-	crc64:F4B136759B7D4636	figure legend:table S1|agonist:H2O2 treatment was required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292	intact-crc:4D61B9DB8265C186|rigid:86lk6XAzT0hEecUK0aQ75TvmpgA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P18239	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-2293|uniprotkb:D6VPW9|ensemblfungi:YBL030C	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:adt2_yeast(display_long)|uniprotkb:PET9(gene name)|psi-mi:PET9(display_short)|uniprotkb:AAC2(gene name synonym)|uniprotkb:YBL030C(locus name)|uniprotkb:YBL0421(orf name)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:Petite colonies protein 9(gene name synonym)|uniprotkb:ADP/ATP translocase 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275413|imex:IM-15826-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	refseq:NP_009523.1|sgd:S000000126|dip:DIP-2917N|mint:P18239|ensemblfungi:YBL030C(gene)|ensemblfungi:YBL030C_mRNA(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009061"(anaerobic respiration)|go:"GO:0015866"(ADP transport)|go:"GO:0015867"(ATP transport)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|rcsb pdb:4C9G|rcsb pdb:4C9H|reactome:R-SCE-1268020|reactome:R-SCE-83936	-	-	crc64:A9805DC33D9E24AC	figure legend:table S1|agonist:H2O2 treatment was required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:kw16b0i/0LOlWLEs0Jcd68KNzJ4559292	intact-crc:4D61B9DB8265C186|rigid:86lk6XAzT0hEecUK0aQ75TvmpgA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P04840	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-13686|uniprotkb:D6W1C3|ensemblfungi:YNL055C	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:vdac1_yeast(display_long)|uniprotkb:POR1(gene name)|psi-mi:POR1(display_short)|uniprotkb:OMP2(gene name synonym)|uniprotkb:VDAC1(gene name synonym)|uniprotkb:YNL055C(locus name)|uniprotkb:N2441(orf name)|uniprotkb:YNL2441C(orf name)|uniprotkb:Voltage-dependent anion-selective channel protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275413|imex:IM-15826-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	refseq:NP_014343.1|sgd:S000005000|ensemblfungi:YNL055C(gene)|ensemblfungi:YNL055C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006811"(ion transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046930"(pore complex)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051027"(DNA transport)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|reactome:R-SCE-70268|mint:P04840|dip:DIP-6453N	-	-	crc64:C99D03711AF9B54D	figure legend:table S1|agonist:H2O2 treatment was required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:RzZ3bLhZ2srdAGXflOSTaAI3fpU559292	intact-crc:4D61B9DB8265C186|rigid:86lk6XAzT0hEecUK0aQ75TvmpgA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P00410	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-5024|uniprotkb:A0A0A7NYF9|ensemblfungi:Q0250	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:cox2_yeast(display_long)|uniprotkb:COX2(gene name)|psi-mi:COX2(display_short)|uniprotkb:OXI1(gene name synonym)|uniprotkb:Q0250(locus name)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275413|imex:IM-15826-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	refseq:NP_009326.1|sgd:S000007281|dip:DIP-7592N|mint:P00410|ensemblfungi:Q0250(gene)|ensemblfungi:Q0250_mRNA(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY	-	-	-	figure legend:table S1|agonist:H2O2 treatment was required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:8vmkrxr7lNbwP25gqqNijmNPY4E559292	intact-crc:4D61B9DB8265C186|rigid:86lk6XAzT0hEecUK0aQ75TvmpgA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P02829	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275405|imex:IM-15826-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N	-	-	crc64:D7C35676D668FB63	figure legend:table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292	intact-crc:B27FBC992CE634E2|rigid:fkKjFH/0JwuZH7SgACM8PF2HC8s	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P39940	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275405|imex:IM-15826-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	-	-	crc64:6F1836384479E70F	figure legend:table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	intact-crc:B27FBC992CE634E2|rigid:fkKjFH/0JwuZH7SgACM8PF2HC8s	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P48558	uniprotkb:P07256	intact:EBI-28349|uniprotkb:Q6B2Q1|uniprotkb:D6W0P0|ensemblfungi:YNL305C	intact:EBI-19922|uniprotkb:D6VPV3|ensemblfungi:YBL045C	psi-mi:bxi1_yeast(display_long)|uniprotkb:BXI1(gene name)|psi-mi:BXI1(display_short)|uniprotkb:YBH3(gene name synonym)|uniprotkb:N0405(orf name)|uniprotkb:YNL305C(locus name)|uniprotkb:BH3 domain-containing protein BXI1(gene name synonym)	psi-mi:qcr1_yeast(display_long)|uniprotkb:COR1(gene name)|psi-mi:COR1(display_short)|uniprotkb:QCR1(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c oxidoreductase core protein 1(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase 44 kDa protein(gene name synonym)|uniprotkb:YBL0403(orf name)|uniprotkb:YBL045C(locus name)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:Core protein I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Buttner et al. (2011)	pubmed:21673659|mint:MINT-8200216|imex:IM-15826	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-5275405|imex:IM-15826-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014094.1|sgd:S000005249|dip:DIP-7944N|mint:P48558|ensemblfungi:YNL305C(gene)|ensemblfungi:YNL305C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR006214(Protein of unknown function UPF0005)	refseq:NP_009508.1|sgd:S000000141|ensemblfungi:YBL045C(gene)|ensemblfungi:YBL045C_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022900"(electron transport chain)|go:"GO:0046872"(metal ion binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|rcsb pdb:1EZV|rcsb pdb:1KB9|rcsb pdb:1KYO|rcsb pdb:1P84|rcsb pdb:2IBZ|rcsb pdb:3CX5|rcsb pdb:3CXH|rcsb pdb:4PD4|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|reactome:R-SCE-611105|dip:DIP-2635N|mint:P07256	-	-	crc64:AE58739EFB695254	figure legend:table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/07/21	2014/10/16	rogid:KvjP1i20jer1kFjh2XWjZHjO5YE559292	rogid:fPEE0SQ86LRkL7Dco2tZ/6rPb4I559292	intact-crc:B27FBC992CE634E2|rigid:fkKjFH/0JwuZH7SgACM8PF2HC8s	false	flag tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)