#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6IT96	uniprotkb:Q66K89	intact:EBI-6979193|intact:UNK-5476148|uniprotkb:D3DPP9	intact:EBI-1227043|uniprotkb:A8K2R4|uniprotkb:O00146|ensembl:ENSP00000301727	psi-mi:q6it96_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:hCG_41610(orf name)	psi-mi:e4f1_human(display_long)|uniprotkb:E4F1(gene name)|psi-mi:E4F1(display_short)|uniprotkb:E4F(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:p50E4F(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979215|mint:MINT-8201110|imex:IM-16054-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007492"(endoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0070888"(E-box binding)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|refseq:NP_004955.2|interpro:IPR023801|interpro:IPR023696|interpro:IPR037138|mint:MINT-8201112(identity)	refseq:NP_001275705.1|refseq:NP_001275707.1|refseq:NP_004415.3|ensembl:ENSP00000301727|ensembl:ENSG00000167967(gene)|ensembl:ENST00000301727(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q66K89|mint:MINT-8201113(identity)	-	comment:mint|comment:homomint	-	figure legend:f6a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606	rogid:WkZmCgVg25mO8Gd8Bl0Nax4dVXE9606	intact-crc:DDA881297F19A0C6|rigid:lMj5tCz/VkA/1CdhTLR634d41yg	false	-	flag tag:?-?(MINT-8201117)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6IT96	uniprotkb:Q04726	intact:EBI-6979193|intact:UNK-5476148|uniprotkb:D3DPP9	intact:EBI-1052057|uniprotkb:Q8IVV6|uniprotkb:Q8WVR2|uniprotkb:Q9HCM5|uniprotkb:B4DPT0|uniprotkb:F8W964|uniprotkb:E9PD64|ensembl:ENSP00000452871|uniprotkb:Q6PI57	psi-mi:q6it96_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:hCG_41610(orf name)	psi-mi:tle3_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 3(gene name synonym)|uniprotkb:TLE3(gene name)|psi-mi:TLE3(display_short)|uniprotkb:KIAA1547(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979230|mint:MINT-8201121|imex:IM-16054-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007492"(endoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0070888"(E-box binding)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|refseq:NP_004955.2|interpro:IPR023801|interpro:IPR023696|interpro:IPR037138|mint:MINT-8201123(identity)	refseq:NP_001098662.1|refseq:NP_005069.2|refseq:NP_065959.1|refseq:NP_001269908.1|refseq:NP_001269909.1|refseq:NP_001269910.1|refseq:NP_001269911.1|ensembl:ENSG00000140332(gene)|ensembl:ENST00000558939(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q04726|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|reactome:R-HSA-9018519|dip:DIP-36666N|mint:MINT-8201125(identity)	-	comment:mint|comment:homomint	-	figure legend:f6b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606	rogid:lbsBYgdnyUWioqJ5euhotXA84Xg9606	intact-crc:4954D2BE76455755|rigid:IbLDXm7PkrIMNAH/GLft7B4uef4	false	-	ha tag:?-?(MINT-8201126)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A4VCF7	uniprotkb:Q6IT96	intact:EBI-6979266|ensembl:ENSDARP00000096499|ensembl:ENSDARP00000146281|intact:MINT-8202486	intact:EBI-6979193|intact:UNK-5476148|uniprotkb:D3DPP9	psi-mi:a4vcf7_danre(display_long)|uniprotkb:"zgc:85925"(gene name synonym)|uniprotkb:lnx2b(gene name)|psi-mi:lnx2b(display_short)|uniprotkb:lnxL(gene name synonym)	psi-mi:q6it96_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:hCG_41610(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979261|mint:MINT-8207141|imex:IM-16054-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSDARG00000071478(gene)|ensembl:ENSDART00000105721(transcript)|ensembl:ENSDART00000182867(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0046872"(metal ion binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|refseq:NP_998105.2|refseq:XP_005173309.1|refseq:XP_005173310.1|mint:MINT-8207145(identity)	go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007492"(endoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0070888"(E-box binding)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|refseq:NP_004955.2|interpro:IPR023801|interpro:IPR023696|interpro:IPR037138|mint:MINT-8207143(identity)	-	comment:mint	comment:mint|comment:homomint	comment:mint|figure legend:f6a f6c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:RNlQtaFaZtIJVRiKqTihjLwES+w7955	rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606	intact-crc:9AF6AACC5A871BBA|rigid:+ANKZKWZl0gWyXWVWdNX/Rb1+KQ	false	flag tag:?-?(MINT-8207146)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9YHE8	uniprotkb:A4VCF7	intact:EBI-6979298|ensembl:ENSDARP00000090035|intact:MINT-8202507	intact:EBI-6979266|ensembl:ENSDARP00000096499|ensembl:ENSDARP00000146281|intact:MINT-8202486	psi-mi:t7l1a_danre(display_long)|uniprotkb:tcf7l1a(gene name)|psi-mi:tcf7l1a(display_short)|uniprotkb:HMG box transcription factor 3-A(gene name synonym)|uniprotkb:Protein headless(gene name synonym)|uniprotkb:hdl(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3a(gene name synonym)	psi-mi:a4vcf7_danre(display_long)|uniprotkb:"zgc:85925"(gene name synonym)|uniprotkb:lnx2b(gene name)|psi-mi:lnx2b(display_short)|uniprotkb:lnxL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979293|mint:MINT-8207151|imex:IM-16054-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSDARG00000038159(gene)|ensembl:ENSDART00000099262(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010456"(cell proliferation in dorsal spinal cord)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060829"(negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation)|go:"GO:0060847"(endothelial cell fate specification)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000054"(negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028778|interpro:IPR036910|reactome:R-DRE-201722|reactome:R-DRE-3769402|reactome:R-DRE-4086398|reactome:R-DRE-4641265|reactome:R-DRE-8853884|reactome:R-DRE-8951430|refseq:NP_571344.1|mint:MINT-8207153(identity)	ensembl:ENSDARG00000071478(gene)|ensembl:ENSDART00000105721(transcript)|ensembl:ENSDART00000182867(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0046872"(metal ion binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|refseq:NP_998105.2|refseq:XP_005173309.1|refseq:XP_005173310.1|mint:MINT-8207155(identity)	-	comment:mint	comment:mint	figure legend:f6a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:5o2KHWGGoX9P83U4ZyfPjAoaiYs7955	rogid:RNlQtaFaZtIJVRiKqTihjLwES+w7955	intact-crc:59484AD68AB60949|rigid:q2nURJBMYVk/GUa5XH7ZHUI1pN0	false	myc tag:?-?(MINT-8207160)	flag tag:?-?(MINT-8207156)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9YHE8	uniprotkb:Q66K89	intact:EBI-6979298|ensembl:ENSDARP00000090035|intact:MINT-8202507	intact:EBI-1227043|uniprotkb:A8K2R4|uniprotkb:O00146|ensembl:ENSP00000301727	psi-mi:t7l1a_danre(display_long)|uniprotkb:tcf7l1a(gene name)|psi-mi:tcf7l1a(display_short)|uniprotkb:HMG box transcription factor 3-A(gene name synonym)|uniprotkb:Protein headless(gene name synonym)|uniprotkb:hdl(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3a(gene name synonym)	psi-mi:e4f1_human(display_long)|uniprotkb:E4F1(gene name)|psi-mi:E4F1(display_short)|uniprotkb:E4F(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:p50E4F(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979346|mint:MINT-8207163|imex:IM-16054-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSDARG00000038159(gene)|ensembl:ENSDART00000099262(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010456"(cell proliferation in dorsal spinal cord)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060829"(negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation)|go:"GO:0060847"(endothelial cell fate specification)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000054"(negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028778|interpro:IPR036910|reactome:R-DRE-201722|reactome:R-DRE-3769402|reactome:R-DRE-4086398|reactome:R-DRE-4641265|reactome:R-DRE-8853884|reactome:R-DRE-8951430|refseq:NP_571344.1|mint:MINT-8207165(identity)	refseq:NP_001275705.1|refseq:NP_001275707.1|refseq:NP_004415.3|ensembl:ENSP00000301727|ensembl:ENSG00000167967(gene)|ensembl:ENST00000301727(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q66K89|mint:MINT-8207167(identity)	-	comment:mint	-	comment:mint|figure legend:f6a sf11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:5o2KHWGGoX9P83U4ZyfPjAoaiYs7955	rogid:WkZmCgVg25mO8Gd8Bl0Nax4dVXE9606	intact-crc:8D5B0D6FBCBF9B4C|rigid:xU44NieaOge607dh1fA23aOlv5g	false	binding-associated region:112-398(MINT-8207382)|myc tag:?-?(MINT-8207173)	flag tag:?-?(MINT-8207168)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A4VCF7	uniprotkb:Q04726	intact:EBI-6979266|ensembl:ENSDARP00000096499|ensembl:ENSDARP00000146281|intact:MINT-8202486	intact:EBI-1052057|uniprotkb:Q8IVV6|uniprotkb:Q8WVR2|uniprotkb:Q9HCM5|uniprotkb:B4DPT0|uniprotkb:F8W964|uniprotkb:E9PD64|ensembl:ENSP00000452871|uniprotkb:Q6PI57	psi-mi:a4vcf7_danre(display_long)|uniprotkb:"zgc:85925"(gene name synonym)|uniprotkb:lnx2b(gene name)|psi-mi:lnx2b(display_short)|uniprotkb:lnxL(gene name synonym)	psi-mi:tle3_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 3(gene name synonym)|uniprotkb:TLE3(gene name)|psi-mi:TLE3(display_short)|uniprotkb:KIAA1547(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979366|mint:MINT-8207178|imex:IM-16054-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSDARG00000071478(gene)|ensembl:ENSDART00000105721(transcript)|ensembl:ENSDART00000182867(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0046872"(metal ion binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|refseq:NP_998105.2|refseq:XP_005173309.1|refseq:XP_005173310.1|mint:MINT-8207182(identity)	refseq:NP_001098662.1|refseq:NP_005069.2|refseq:NP_065959.1|refseq:NP_001269908.1|refseq:NP_001269909.1|refseq:NP_001269910.1|refseq:NP_001269911.1|ensembl:ENSG00000140332(gene)|ensembl:ENST00000558939(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q04726|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|reactome:R-HSA-9018519|dip:DIP-36666N|mint:MINT-8207180(identity)	-	comment:mint	-	comment:mint|figure legend:f6a f6c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:RNlQtaFaZtIJVRiKqTihjLwES+w7955	rogid:lbsBYgdnyUWioqJ5euhotXA84Xg9606	intact-crc:27DAB1D2CB9F5295|rigid:ivGeBwdjlV7AOjT7Gf0blYyWA8A	false	flag tag:?-?(MINT-8207183)	ha tag:?-?(MINT-8207187)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6IT96	uniprotkb:Q9YHE8	intact:EBI-6979193|intact:UNK-5476148|uniprotkb:D3DPP9	intact:EBI-6979298|ensembl:ENSDARP00000090035|intact:MINT-8202507	psi-mi:q6it96_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:hCG_41610(orf name)	psi-mi:t7l1a_danre(display_long)|uniprotkb:tcf7l1a(gene name)|psi-mi:tcf7l1a(display_short)|uniprotkb:HMG box transcription factor 3-A(gene name synonym)|uniprotkb:Protein headless(gene name synonym)|uniprotkb:hdl(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979383|mint:MINT-8207190|imex:IM-16054-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007492"(endoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0070888"(E-box binding)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|refseq:NP_004955.2|interpro:IPR023801|interpro:IPR023696|interpro:IPR037138|mint:MINT-8207192(identity)	ensembl:ENSDARG00000038159(gene)|ensembl:ENSDART00000099262(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010456"(cell proliferation in dorsal spinal cord)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060829"(negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation)|go:"GO:0060847"(endothelial cell fate specification)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000054"(negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028778|interpro:IPR036910|reactome:R-DRE-201722|reactome:R-DRE-3769402|reactome:R-DRE-4086398|reactome:R-DRE-4641265|reactome:R-DRE-8853884|reactome:R-DRE-8951430|refseq:NP_571344.1|mint:MINT-8207196(identity)	-	comment:mint|comment:homomint	comment:mint	figure legend:f6c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606	rogid:5o2KHWGGoX9P83U4ZyfPjAoaiYs7955	intact-crc:F73ADCC39B3CB266|rigid:dNbVrS3NWW1zljBXOXlklnh7VAE	false	-	myc tag:?-?(MINT-8207197)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6IT96	uniprotkb:Q66K89	intact:EBI-6979193|intact:UNK-5476148|uniprotkb:D3DPP9	intact:EBI-1227043|uniprotkb:A8K2R4|uniprotkb:O00146|ensembl:ENSP00000301727	psi-mi:q6it96_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:hCG_41610(orf name)	psi-mi:e4f1_human(display_long)|uniprotkb:E4F1(gene name)|psi-mi:E4F1(display_short)|uniprotkb:E4F(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:p50E4F(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979431|mint:MINT-8207218|imex:IM-16054-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007492"(endoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0070888"(E-box binding)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|refseq:NP_004955.2|interpro:IPR023801|interpro:IPR023696|interpro:IPR037138|mint:MINT-8207224(identity)	refseq:NP_001275705.1|refseq:NP_001275707.1|refseq:NP_004415.3|ensembl:ENSP00000301727|ensembl:ENSG00000167967(gene)|ensembl:ENST00000301727(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q66K89|mint:MINT-8207220(identity)	-	comment:mint|comment:homomint	-	figure legend:f6c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606	rogid:WkZmCgVg25mO8Gd8Bl0Nax4dVXE9606	intact-crc:45F428309BF1CD60|rigid:lMj5tCz/VkA/1CdhTLR634d41yg	false	-	t7 tag:?-?(MINT-8207221)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9YHE8	uniprotkb:Q04726	intact:EBI-6979298|ensembl:ENSDARP00000090035|intact:MINT-8202507	intact:EBI-1052057|uniprotkb:Q8IVV6|uniprotkb:Q8WVR2|uniprotkb:Q9HCM5|uniprotkb:B4DPT0|uniprotkb:F8W964|uniprotkb:E9PD64|ensembl:ENSP00000452871|uniprotkb:Q6PI57	psi-mi:t7l1a_danre(display_long)|uniprotkb:tcf7l1a(gene name)|psi-mi:tcf7l1a(display_short)|uniprotkb:HMG box transcription factor 3-A(gene name synonym)|uniprotkb:Protein headless(gene name synonym)|uniprotkb:hdl(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3a(gene name synonym)	psi-mi:tle3_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 3(gene name synonym)|uniprotkb:TLE3(gene name)|psi-mi:TLE3(display_short)|uniprotkb:KIAA1547(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979413|mint:MINT-8207205|imex:IM-16054-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSDARG00000038159(gene)|ensembl:ENSDART00000099262(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010456"(cell proliferation in dorsal spinal cord)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060829"(negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation)|go:"GO:0060847"(endothelial cell fate specification)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000054"(negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028778|interpro:IPR036910|reactome:R-DRE-201722|reactome:R-DRE-3769402|reactome:R-DRE-4086398|reactome:R-DRE-4641265|reactome:R-DRE-8853884|reactome:R-DRE-8951430|refseq:NP_571344.1|mint:MINT-8207207(identity)	refseq:NP_001098662.1|refseq:NP_005069.2|refseq:NP_065959.1|refseq:NP_001269908.1|refseq:NP_001269909.1|refseq:NP_001269910.1|refseq:NP_001269911.1|ensembl:ENSG00000140332(gene)|ensembl:ENST00000558939(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q04726|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|reactome:R-HSA-9018519|dip:DIP-36666N|mint:MINT-8207211(identity)	-	comment:mint	-	figure legend:f6c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:5o2KHWGGoX9P83U4ZyfPjAoaiYs7955	rogid:lbsBYgdnyUWioqJ5euhotXA84Xg9606	intact-crc:43F9AE0C3A66356B|rigid:+20AlbzwfIJjnngYcvF4bFV+PRc	false	myc tag:?-?(MINT-8207208)	ha tag:?-?(MINT-8207214)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A4VCF7	uniprotkb:Q66K89	intact:EBI-6979266|ensembl:ENSDARP00000096499|ensembl:ENSDARP00000146281|intact:MINT-8202486	intact:EBI-1227043|uniprotkb:A8K2R4|uniprotkb:O00146|ensembl:ENSP00000301727	psi-mi:a4vcf7_danre(display_long)|uniprotkb:"zgc:85925"(gene name synonym)|uniprotkb:lnx2b(gene name)|psi-mi:lnx2b(display_short)|uniprotkb:lnxL(gene name synonym)	psi-mi:e4f1_human(display_long)|uniprotkb:E4F1(gene name)|psi-mi:E4F1(display_short)|uniprotkb:E4F(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:p50E4F(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979465|mint:MINT-8207302|imex:IM-16054-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSDARG00000071478(gene)|ensembl:ENSDART00000105721(transcript)|ensembl:ENSDART00000182867(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0046872"(metal ion binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|refseq:NP_998105.2|refseq:XP_005173309.1|refseq:XP_005173310.1|mint:MINT-8207306(identity)	refseq:NP_001275705.1|refseq:NP_001275707.1|refseq:NP_004415.3|ensembl:ENSP00000301727|ensembl:ENSG00000167967(gene)|ensembl:ENST00000301727(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q66K89|mint:MINT-8207304(identity)	-	comment:mint	-	figure legend:sf1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:RNlQtaFaZtIJVRiKqTihjLwES+w7955	rogid:WkZmCgVg25mO8Gd8Bl0Nax4dVXE9606	intact-crc:972669025313087D|rigid:Ux0N0Yya2ve4mwMFQapJ++uHrxk	false	mutation increasing interaction:1-83(MINT-8207325)|flag tag:?-?(MINT-8207307)	t7 tag:?-?(MINT-8207320)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9YHE8	uniprotkb:Q66K89	intact:EBI-6979298|ensembl:ENSDARP00000090035|intact:MINT-8202507	intact:EBI-1227043|uniprotkb:A8K2R4|uniprotkb:O00146|ensembl:ENSP00000301727	psi-mi:t7l1a_danre(display_long)|uniprotkb:tcf7l1a(gene name)|psi-mi:tcf7l1a(display_short)|uniprotkb:HMG box transcription factor 3-A(gene name synonym)|uniprotkb:Protein headless(gene name synonym)|uniprotkb:hdl(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3a(gene name synonym)	psi-mi:e4f1_human(display_long)|uniprotkb:E4F1(gene name)|psi-mi:E4F1(display_short)|uniprotkb:E4F(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:p50E4F(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979447|mint:MINT-8207228|imex:IM-16054-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSDARG00000038159(gene)|ensembl:ENSDART00000099262(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010456"(cell proliferation in dorsal spinal cord)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060829"(negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation)|go:"GO:0060847"(endothelial cell fate specification)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000054"(negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028778|interpro:IPR036910|reactome:R-DRE-201722|reactome:R-DRE-3769402|reactome:R-DRE-4086398|reactome:R-DRE-4641265|reactome:R-DRE-8853884|reactome:R-DRE-8951430|refseq:NP_571344.1|mint:MINT-8207230(identity)	refseq:NP_001275705.1|refseq:NP_001275707.1|refseq:NP_004415.3|ensembl:ENSP00000301727|ensembl:ENSG00000167967(gene)|ensembl:ENST00000301727(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q66K89|mint:MINT-8207232(identity)	-	comment:mint	-	figure legend:f6c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:5o2KHWGGoX9P83U4ZyfPjAoaiYs7955	rogid:WkZmCgVg25mO8Gd8Bl0Nax4dVXE9606	intact-crc:1E552C5FF6AF9282|rigid:xU44NieaOge607dh1fA23aOlv5g	false	myc tag:?-?(MINT-8207238)	t7 tag:?-?(MINT-8207233)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A4VCF7	uniprotkb:Q66K89	intact:EBI-6979266|ensembl:ENSDARP00000096499|ensembl:ENSDARP00000146281|intact:MINT-8202486	intact:EBI-1227043|uniprotkb:A8K2R4|uniprotkb:O00146|ensembl:ENSP00000301727	psi-mi:a4vcf7_danre(display_long)|uniprotkb:"zgc:85925"(gene name synonym)|uniprotkb:lnx2b(gene name)|psi-mi:lnx2b(display_short)|uniprotkb:lnxL(gene name synonym)	psi-mi:e4f1_human(display_long)|uniprotkb:E4F1(gene name)|psi-mi:E4F1(display_short)|uniprotkb:E4F(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:p50E4F(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979502|mint:MINT-8207329|imex:IM-16054-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSDARG00000071478(gene)|ensembl:ENSDART00000105721(transcript)|ensembl:ENSDART00000182867(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0046872"(metal ion binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|refseq:NP_998105.2|refseq:XP_005173309.1|refseq:XP_005173310.1|mint:MINT-8207331(identity)	refseq:NP_001275705.1|refseq:NP_001275707.1|refseq:NP_004415.3|ensembl:ENSP00000301727|ensembl:ENSG00000167967(gene)|ensembl:ENST00000301727(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q66K89|mint:MINT-8207337(identity)	-	comment:mint	-	figure legend:sf1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:RNlQtaFaZtIJVRiKqTihjLwES+w7955	rogid:WkZmCgVg25mO8Gd8Bl0Nax4dVXE9606	intact-crc:AB1A009205FB2619|rigid:Ux0N0Yya2ve4mwMFQapJ++uHrxk	false	flag tag:?-?(MINT-8207334)|mutation increasing interaction:63-63(MINT-8207343)|mutation increasing interaction:66-66(MINT-8207332)	t7 tag:?-?(MINT-8207338)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8TBB1	uniprotkb:Q66K89	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	intact:EBI-1227043|uniprotkb:A8K2R4|uniprotkb:O00146|ensembl:ENSP00000301727	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:e4f1_human(display_long)|uniprotkb:E4F1(gene name)|psi-mi:E4F1(display_short)|uniprotkb:E4F(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:p50E4F(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979528|mint:MINT-8207347|imex:IM-16054-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168|mint:MINT-8207349(identity)	refseq:NP_001275705.1|refseq:NP_001275707.1|refseq:NP_004415.3|ensembl:ENSP00000301727|ensembl:ENSG00000167967(gene)|ensembl:ENST00000301727(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q66K89|mint:MINT-8207357(identity)	-	-	-	figure legend:sf1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	rogid:WkZmCgVg25mO8Gd8Bl0Nax4dVXE9606	intact-crc:24587AD10F0373B2|rigid:FFqrSGgFF4r60ZlYLRIWdYT5HEk	false	flag tag:?-?(MINT-8207354)	myc tag:?-?(MINT-8207358)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q66K89	uniprotkb:Q8N448	intact:EBI-1227043|uniprotkb:A8K2R4|uniprotkb:O00146|ensembl:ENSP00000301727	intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224	psi-mi:e4f1_human(display_long)|uniprotkb:E4F1(gene name)|psi-mi:E4F1(display_short)|uniprotkb:E4F(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:p50E4F(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym)	psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979546|mint:MINT-8207368|imex:IM-16054-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001275705.1|refseq:NP_001275707.1|refseq:NP_004415.3|ensembl:ENSP00000301727|ensembl:ENSG00000167967(gene)|ensembl:ENST00000301727(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q66K89|mint:MINT-8207370(identity)	refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22|mint:MINT-8207374(identity)	-	-	-	figure legend:sf1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/07/25	2014/10/16	rogid:WkZmCgVg25mO8Gd8Bl0Nax4dVXE9606	rogid:cIS5t4XkbnIgelDlUc692nI285g9606	intact-crc:C15ACDADA40BB7A5|rigid:+WWM99bjVTiWrSCybdnGyIVzzm0	false	myc tag:?-?(MINT-8207371)	flag tag:?-?(MINT-8207375)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A4VCF7	uniprotkb:Q66K89	intact:EBI-6979266|ensembl:ENSDARP00000096499|ensembl:ENSDARP00000146281|intact:MINT-8202486	intact:EBI-1227043|uniprotkb:A8K2R4|uniprotkb:O00146|ensembl:ENSP00000301727	psi-mi:a4vcf7_danre(display_long)|uniprotkb:"zgc:85925"(gene name synonym)|uniprotkb:lnx2b(gene name)|psi-mi:lnx2b(display_short)|uniprotkb:lnxL(gene name synonym)	psi-mi:e4f1_human(display_long)|uniprotkb:E4F1(gene name)|psi-mi:E4F1(display_short)|uniprotkb:E4F(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:p50E4F(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ro et al. (2011)	pubmed:21666599|imex:IM-16054|mint:MINT-8201084|doi:10.1038/emboj.2011.184	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-6979573|mint:MINT-8207245|imex:IM-16054-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSDARG00000071478(gene)|ensembl:ENSDART00000105721(transcript)|ensembl:ENSDART00000182867(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0046872"(metal ion binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|refseq:NP_998105.2|refseq:XP_005173309.1|refseq:XP_005173310.1|mint:MINT-8207249(identity)	refseq:NP_001275705.1|refseq:NP_001275707.1|refseq:NP_004415.3|ensembl:ENSP00000301727|ensembl:ENSG00000167967(gene)|ensembl:ENST00000301727(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q66K89|mint:MINT-8207247(identity)	-	comment:mint	-	figure legend:sf1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/07/25	2014/10/16	rogid:RNlQtaFaZtIJVRiKqTihjLwES+w7955	rogid:WkZmCgVg25mO8Gd8Bl0Nax4dVXE9606	intact-crc:FFEB609E5AF64750|rigid:Ux0N0Yya2ve4mwMFQapJ++uHrxk	false	tag:?-?(MINT-8207250)	glutathione s tranferase tag:?-?(MINT-8207257)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)