#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9JHG7	uniprotkb:P35969	intact:EBI-644372|uniprotkb:Q80V09|ensembl:ENSMUSP00000062864|ensembl:ENSMUSP00000082596|ensembl:ENSMUSP00000123539|ensembl:ENSMUSP00000151400	intact:EBI-1554752|uniprotkb:O55094|uniprotkb:Q61517	psi-mi:pk3cg_mouse(display_long)|uniprotkb:p120-PI3K(gene name synonym)|uniprotkb:Pik3cg(gene name)|psi-mi:Pik3cg(display_short)|uniprotkb:Pi3kg1(gene name synonym)|uniprotkb:Phosphoinositide-3-kinase catalytic gamma polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CG(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma(gene name synonym)	psi-mi:vgfr1_mouse(display_long)|uniprotkb:Tyrosine-protein kinase receptor FLT(gene name synonym)|uniprotkb:Fms-like tyrosine kinase 1(gene name synonym)|uniprotkb:Embryonic receptor kinase 2(gene name synonym)|uniprotkb:Flt1(gene name)|psi-mi:Flt1(display_short)|uniprotkb:Emrk2(gene name synonym)|uniprotkb:Flt(gene name synonym)|uniprotkb:Vegfr1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schmid et al. (2011)	pubmed:21665146|imex:IM-15815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4303889|imex:IM-15815-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139672.1|refseq:NP_001139673.1|refseq:NP_064668.2|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|ensembl:ENSMUSG00000020573(gene)|ensembl:ENSMUST00000053215(transcript)|ensembl:ENSMUST00000085469(transcript)|ensembl:ENSMUST00000156904(transcript)|ensembl:ENSMUST00000220366(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0032252"(secretory granule localization)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|reactome:R-MMU-114604|reactome:R-MMU-1660499|reactome:R-MMU-392451|reactome:R-MMU-9027276|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|refseq:XP_006515175.1|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|dip:DIP-41862N	refseq:NP_034358.2|mint:P35969|dip:DIP-39359N|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005021"(vascular endothelial growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036323"(vascular endothelial growth factor receptor-1 signaling pathway)|go:"GO:0036332"(placental growth factor-activated receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009135(Vascular endothelial growth factor receptor 1, VEGFR1, N-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|interpro:IPR041348|reactome:R-MMU-194306|reactome:R-MMU-195399	psi-mi:"MI:0469"(intact)	-	-	figure legend:5D, S5B.|antagonist:SDF-1alpha|agonist:VEGF-A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bone-marrow)|taxid:10090(Mouse bone marrow)	-	2011/07/13	2014/10/16	rogid:SV/AI6H65Utm5ENkfXkXQ4lqaao10090	rogid:h8ZisQ4hFcNEoJwYpnhQ9OCMvcY10090	intact-crc:6CCED0E31285F687|rigid:HiikJ5291VLyzc10d+101fpQ9mg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JHG7	uniprotkb:P70658	intact:EBI-644372|uniprotkb:Q80V09|ensembl:ENSMUSP00000062864|ensembl:ENSMUSP00000082596|ensembl:ENSMUSP00000123539|ensembl:ENSMUSP00000151400	intact:EBI-4303896|uniprotkb:O09059|uniprotkb:O09062|uniprotkb:P70233|uniprotkb:P70346|uniprotkb:Q4KMW1	psi-mi:pk3cg_mouse(display_long)|uniprotkb:p120-PI3K(gene name synonym)|uniprotkb:Pik3cg(gene name)|psi-mi:Pik3cg(display_short)|uniprotkb:Pi3kg1(gene name synonym)|uniprotkb:Phosphoinositide-3-kinase catalytic gamma polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CG(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma(gene name synonym)	psi-mi:cxcr4_mouse(display_long)|uniprotkb:Cxcr4(gene name)|psi-mi:Cxcr4(display_short)|uniprotkb:Cmkar4(gene name synonym)|uniprotkb:Lestr(gene name synonym)|uniprotkb:Sdf1r(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:Pre-B-cell-derived chemokine receptor(gene name synonym)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schmid et al. (2011)	pubmed:21665146|imex:IM-15815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4303893|imex:IM-15815-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139672.1|refseq:NP_001139673.1|refseq:NP_064668.2|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|ensembl:ENSMUSG00000020573(gene)|ensembl:ENSMUST00000053215(transcript)|ensembl:ENSMUST00000085469(transcript)|ensembl:ENSMUST00000156904(transcript)|ensembl:ENSMUST00000220366(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0032252"(secretory granule localization)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|reactome:R-MMU-114604|reactome:R-MMU-1660499|reactome:R-MMU-392451|reactome:R-MMU-9027276|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|refseq:XP_006515175.1|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|dip:DIP-41862N	refseq:NP_034041.2|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|interpro:IPR022726|interpro:IPR000355(Chemokine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0035904"(aorta development)|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043217"(myelin maintenance)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048699"(generation of neurons)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0001822"(kidney development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007281"(germ cell development)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008354"(germ cell migration)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|reactome:R-MMU-376176|reactome:R-MMU-380108|reactome:R-MMU-418594	psi-mi:"MI:0469"(intact)	-	-	figure legend:5D|antagonist:VEGF-A|agonist:SDF-1alpha|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bone-marrow)|taxid:10090(Mouse bone marrow)	-	2011/07/13	2014/10/16	rogid:SV/AI6H65Utm5ENkfXkXQ4lqaao10090	rogid:e8jWbjKMZ36DKVNFLM1MOy2QXHA10090	intact-crc:932E9634D5C04872|rigid:ZQ0QaqJQCGxdeSZHAZiRim80MLg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JHG7	uniprotkb:Q3U6Q4	intact:EBI-644372|uniprotkb:Q80V09|ensembl:ENSMUSP00000062864|ensembl:ENSMUSP00000082596|ensembl:ENSMUSP00000123539|ensembl:ENSMUSP00000151400	intact:EBI-4303950|uniprotkb:Q3UAY4|uniprotkb:Q8K323|uniprotkb:Q3TBT5|ensembl:ENSMUSP00000052522	psi-mi:pk3cg_mouse(display_long)|uniprotkb:p120-PI3K(gene name synonym)|uniprotkb:Pik3cg(gene name)|psi-mi:Pik3cg(display_short)|uniprotkb:Pi3kg1(gene name synonym)|uniprotkb:Phosphoinositide-3-kinase catalytic gamma polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CG(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma(gene name synonym)	psi-mi:pi3r6_mouse(display_long)|uniprotkb:Pik3r6(gene name)|psi-mi:Pik3r6(display_short)|uniprotkb:Phosphoinositide 3-kinase gamma adapter protein of 87 kDa(gene name synonym)|uniprotkb:p87 PI3K adapter protein(gene name synonym)|uniprotkb:p84 PI3K adapter protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schmid et al. (2011)	pubmed:21665146|imex:IM-15815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4303944|imex:IM-15815-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139672.1|refseq:NP_001139673.1|refseq:NP_064668.2|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|ensembl:ENSMUSG00000020573(gene)|ensembl:ENSMUST00000053215(transcript)|ensembl:ENSMUST00000085469(transcript)|ensembl:ENSMUST00000156904(transcript)|ensembl:ENSMUST00000220366(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0032252"(secretory granule localization)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|reactome:R-MMU-114604|reactome:R-MMU-1660499|reactome:R-MMU-392451|reactome:R-MMU-9027276|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|refseq:XP_006515175.1|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|dip:DIP-41862N	refseq:NP_001004435.1|refseq:NP_001075035.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0042269"(regulation of natural killer cell mediated cytotoxicity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR019522|reactome:R-MMU-114604|reactome:R-MMU-1660499|reactome:R-MMU-392451|ensembl:ENSMUSG00000046207(gene)|ensembl:ENSMUST00000060441(transcript)|go:"GO:0001525"(angiogenesis)|dip:DIP-60179N	psi-mi:"MI:0469"(intact)	-	-	figure legend:5E|agonist:VEGF-A- for the p100gamma/p87 interaction  SDF-1alpha for the -p100gamma/p101 interaction|antagonist:SDF-1alpha for the -p100gamma/p87 interaction  VEGF-A  for the -p100gamma/p101 interaction|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bone-marrow)|taxid:10090(Mouse bone marrow)	-	2011/07/13	2014/10/16	rogid:SV/AI6H65Utm5ENkfXkXQ4lqaao10090	rogid:poDoOV1PYQoviR5fRo/2ipnGjKs10090	intact-crc:CEE754C2A18A3C39|rigid:qlqUC+Wb00yyHQeT9sUfXolFufY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JHG7	uniprotkb:Q5SW28	intact:EBI-644372|uniprotkb:Q80V09|ensembl:ENSMUSP00000062864|ensembl:ENSMUSP00000082596|ensembl:ENSMUSP00000123539|ensembl:ENSMUSP00000151400	intact:EBI-4303969|uniprotkb:Q3TU01|uniprotkb:Q3UDZ2|uniprotkb:Q8C215|uniprotkb:Q8CGQ7|ensembl:ENSMUSP00000021283	psi-mi:pk3cg_mouse(display_long)|uniprotkb:p120-PI3K(gene name synonym)|uniprotkb:Pik3cg(gene name)|psi-mi:Pik3cg(display_short)|uniprotkb:Pi3kg1(gene name synonym)|uniprotkb:Phosphoinositide-3-kinase catalytic gamma polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CG(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma(gene name synonym)	psi-mi:pi3r5_mouse(display_long)|uniprotkb:Pik3r5(gene name)|psi-mi:Pik3r5(display_short)|uniprotkb:PI3-kinase p101 subunit(gene name synonym)|uniprotkb:PtdIns-3-kinase p101(gene name synonym)|uniprotkb:p101-PI3K(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schmid et al. (2011)	pubmed:21665146|imex:IM-15815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4303944|imex:IM-15815-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139672.1|refseq:NP_001139673.1|refseq:NP_064668.2|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|ensembl:ENSMUSG00000020573(gene)|ensembl:ENSMUST00000053215(transcript)|ensembl:ENSMUST00000085469(transcript)|ensembl:ENSMUST00000156904(transcript)|ensembl:ENSMUST00000220366(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0032252"(secretory granule localization)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|reactome:R-MMU-114604|reactome:R-MMU-1660499|reactome:R-MMU-392451|reactome:R-MMU-9027276|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|refseq:XP_006515175.1|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|dip:DIP-41862N	refseq:NP_796294.2|refseq:XP_006533611.1|reactome:R-MMU-392451|reactome:R-MMU-9027276|ensembl:ENSMUSG00000020901(gene)|ensembl:ENSMUST00000021283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|interpro:IPR019522|reactome:R-MMU-114604|reactome:R-MMU-1660499	psi-mi:"MI:0469"(intact)	-	-	figure legend:5E|agonist:VEGF-A- for the p100gamma/p87 interaction  SDF-1alpha for the -p100gamma/p101 interaction|antagonist:SDF-1alpha for the -p100gamma/p87 interaction  VEGF-A  for the -p100gamma/p101 interaction|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bone-marrow)|taxid:10090(Mouse bone marrow)	-	2011/07/13	2014/10/16	rogid:SV/AI6H65Utm5ENkfXkXQ4lqaao10090	rogid:zQMWsyVX4qcX4jkZoQPnlsmJgJA10090	intact-crc:CEE754C2A18A3C39|rigid:qlqUC+Wb00yyHQeT9sUfXolFufY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)