#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:B3XYC5 uniprotkb:O95297 intact:EBI-4319310 intact:EBI-963338|ensembl:ENSP00000352513|uniprotkb:Q5R332|uniprotkb:Q8IX11|uniprotkb:Q9BWZ3|uniprotkb:Q9NYK4|uniprotkb:Q9UL20|uniprotkb:B2REB9|uniprotkb:B2REC0 psi-mi:b3xyc5_sollc(display_long) psi-mi:mpzl1_human(display_long)|uniprotkb:MPZL1(gene name)|psi-mi:MPZL1(display_short)|uniprotkb:PZR(gene name synonym)|uniprotkb:UNQ849/PRO1787(orf name)|uniprotkb:Protein zero-related(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) ensembl:ENSG00000197965(gene)|ensembl:ENST00000359523(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009986"(cell surface)|interpro:IPR000920(Myelin P0 protein)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029870|interpro:IPR036179|rcsb pdb:6IGO|rcsb pdb:6IGT|rcsb pdb:6IGW|refseq:NP_003944.1|refseq:NP_078845.3|refseq:NP_001139663.1 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:NdvJG6RocnCX10KdIhiJ9LmwMNs9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:O15439 intact:EBI-4319310 intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609 psi-mi:b3xyc5_sollc(display_long) psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q96NT5 intact:EBI-4319310 intact:EBI-4319513|uniprotkb:Q1HE20|uniprotkb:Q86T92|uniprotkb:Q8TEG3|uniprotkb:Q96FL0|ensembl:ENSP00000480703 psi-mi:b3xyc5_sollc(display_long) psi-mi:pcft_human(display_long)|uniprotkb:HCP1(gene name synonym)|uniprotkb:PCFT(gene name synonym)|uniprotkb:G21(gene name synonym)|uniprotkb:Heme carrier protein 1(gene name synonym)|uniprotkb:PCFT/HCP1(gene name synonym)|uniprotkb:Solute carrier family 46 member 1(gene name synonym)|uniprotkb:SLC46A1(gene name)|psi-mi:SLC46A1(display_short) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001229295.1|refseq:NP_542400.2|ensembl:ENSG00000076351(gene)|ensembl:ENST00000612814(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008517"(folic acid transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015350"(methotrexate transmembrane transporter activity)|go:"GO:0015884"(folic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0042168"(heme metabolic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0051958"(methotrexate transport)|go:"GO:0098829"(intestinal folate absorption)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904447"(folate import across plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|mint:Q96NT5|reactome:R-HSA-196757|reactome:R-HSA-917937|reactome:R-HSA-9707616 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:b0cJ4xSftwT+ZdfYSlp0ZSAol5g9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P13473 intact:EBI-4319310 intact:EBI-2907154|uniprotkb:A8K4X5|uniprotkb:Q16641|uniprotkb:Q96J30|uniprotkb:Q99534|uniprotkb:Q9UD93|uniprotkb:D3DTF0|intact:EBI-4324646|uniprotkb:Q6Q3G8|ensembl:ENSP00000200639 psi-mi:b3xyc5_sollc(display_long) psi-mi:lamp2_human(display_long)|uniprotkb:LAMP2(gene name)|psi-mi:LAMP2(display_short)|uniprotkb:CD107 antigen-like family member B(gene name synonym)|uniprotkb:LGP-96(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_002285.1|refseq:NP_054701.1|refseq:NP_001116078.1|ensembl:ENSG00000005893(gene)|ensembl:ENST00000200639(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0017038"(protein import)|go:"GO:0019899"(enzyme binding)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0044754"(autolysosome)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0061742"(chaperone-mediated autophagy translocation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097637"(integral component of autophagosome membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1990836"(lysosomal matrix)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P13473|rcsb pdb:2MOF|rcsb pdb:2MOM|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-9613829 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:+s4K/qoL3PBwjATJmFDQtqcl/ZQ9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q6J4K2 intact:EBI-4319310 intact:EBI-4319571|uniprotkb:Q4KMS9|uniprotkb:A6NP50|uniprotkb:Q6J4K1|uniprotkb:Q9H6I8|ensembl:ENSP00000202831|ensembl:ENSP00000447091|ensembl:ENSP00000506377 psi-mi:b3xyc5_sollc(display_long) psi-mi:nclx_human(display_long)|uniprotkb:Sodium/potassium/calcium exchanger 6(gene name synonym)|uniprotkb:SLC8B1(gene name)|psi-mi:SLC8B1(display_short)|uniprotkb:NCKX6(gene name synonym)|uniprotkb:NCLX(gene name synonym)|uniprotkb:"Na(+)/K(+)/Ca(2+)-exchange protein 6"(gene name synonym)|uniprotkb:SLC24A6(gene name synonym)|uniprotkb:Sodium/calcium exchanger protein, mitochondrial(gene name synonym)|uniprotkb:Solute carrier family 24 member 6(gene name synonym)|uniprotkb:Solute carrier family 8 member B1(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_079235.2|refseq:XP_011537051.1|refseq:XP_011537054.1|refseq:XP_006719670.1|refseq:NP_001317395.1|ensembl:ENSG00000089060(gene)|ensembl:ENST00000202831(transcript)|ensembl:ENST00000552014(transcript)|ensembl:ENST00000680972(transcript)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006812"(cation transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0015368"("calcium:cation antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050896"(response to stimulus)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086038"("calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential")|go:"GO:0099093"(calcium export from the mitochondrion)|go:"GO:1901623"(regulation of lymphocyte chemotaxis)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|reactome:R-HSA-425561|reactome:R-HSA-8949215 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:aLpScg3tn5xVqT/LgN8vgPDHF4I9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P08962 intact:EBI-4319310 intact:EBI-762053|uniprotkb:Q5TZP3|uniprotkb:Q9UCG6|uniprotkb:Q8N6Z9|uniprotkb:F8VZE2|ensembl:ENSP00000257857|ensembl:ENSP00000393502|ensembl:ENSP00000447730|ensembl:ENSP00000449337 psi-mi:b3xyc5_sollc(display_long) psi-mi:cd63_human(display_long)|uniprotkb:Melanoma-associated antigen ME491(gene name synonym)|uniprotkb:Ocular melanoma-associated antigen(gene name synonym)|uniprotkb:OMA81H(gene name synonym)|uniprotkb:Granulophysin(gene name synonym)|uniprotkb:Tetraspanin-30(gene name synonym)|uniprotkb:Lysosomal-associated membrane protein 3(gene name synonym)|uniprotkb:CD63(gene name)|psi-mi:CD63(display_short)|uniprotkb:MLA1(gene name synonym)|uniprotkb:TSPAN30(gene name synonym)|uniprotkb:Lysosome integral membrane protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001771.1|refseq:NP_001244330.1|refseq:NP_001244318.1|refseq:NP_001244319.1|refseq:NP_001244320.1|refseq:NP_001244329.1|refseq:NP_001254627.1|refseq:NP_001244321.1|ensembl:ENSG00000135404(gene)|ensembl:ENST00000257857(transcript)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042028|mint:P08962|reactome:R-HSA-114608|reactome:R-HSA-6798695|go:"GO:0097487"(multivesicular body, internal vesicle)|ensembl:ENST00000420846(transcript)|ensembl:ENST00000549117(transcript)|ensembl:ENST00000552692(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016477"(cell migration)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048757"(pigment granule maturation)|go:"GO:0070062"(extracellular exosome) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:stCGi5kkTMIdO84qSwjmjpUwwvs9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q8N697 intact:EBI-4319310 intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771 psi-mi:b3xyc5_sollc(display_long) psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:vu4B0G9993k3P93S7sN31ky7l889606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q9HBW9 intact:EBI-4319310 intact:EBI-4319658|uniprotkb:B1AR71|uniprotkb:Q5KU34|ensembl:ENSP00000359778 psi-mi:b3xyc5_sollc(display_long) psi-mi:agrl4_human(display_long)|uniprotkb:ADGRL4(gene name)|psi-mi:ADGRL4(display_short)|uniprotkb:EGF, latrophilin and seven transmembrane domain-containing protein 1(gene name synonym)|uniprotkb:EGF-TM7-latrophilin-related protein(gene name synonym)|uniprotkb:ELTD1(gene name synonym)|uniprotkb:ETL(gene name synonym)|uniprotkb:UNQ202/PRO228(orf name) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_071442.2|ensembl:ENSG00000162618(gene)|ensembl:ENST00000370742(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000203(GPS)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR017981|interpro:IPR017983|interpro:IPR018097|interpro:IPR032471 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:XGCuNB7iTpL+G4bTs+1JtRlI+rM9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q96T83 intact:EBI-4319310 intact:EBI-4319546|uniprotkb:O75827|uniprotkb:Q5JXP9|ensembl:ENSP00000330320 psi-mi:b3xyc5_sollc(display_long) psi-mi:sl9a7_human(display_long)|uniprotkb:SLC9A7(gene name)|psi-mi:SLC9A7(display_short)|uniprotkb:NHE7(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 7"(gene name synonym)|uniprotkb:Solute carrier family 9 member 7(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_115980.1|ensembl:ENSG00000065923(gene)|ensembl:ENST00000328306(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:1905526"(regulation of Golgi lumen acidification)|interpro:IPR002090("Na+/H+ exchanger, isoform 6 (NHE6)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|reactome:R-HSA-425986 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:kFnCBomaj+J+6Wgh7lU/GPcKROA9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q9Y487 intact:EBI-4319310 intact:EBI-988630|ensembl:ENSP00000332247|uniprotkb:Q6NUM0|uniprotkb:A8K026 psi-mi:b3xyc5_sollc(display_long) psi-mi:vpp2_human(display_long)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2(gene name synonym)|uniprotkb:"Lysosomal H(+)-transporting ATPase V0 subunit a2"(gene name synonym)|uniprotkb:TJ6(gene name synonym)|uniprotkb:ATP6V0A2(gene name)|psi-mi:ATP6V0A2(display_short) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) ensembl:ENSG00000185344(gene)|ensembl:ENST00000330342(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006955"(immune response)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|mint:Q9Y487|refseq:NP_036595.2|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-983712 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:I4UxvwiAe4ObvfgL15K2lzNKuOA9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P13987 intact:EBI-4319310 intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17 psi-mi:b3xyc5_sollc(display_long) psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P04156 intact:EBI-4319310 intact:EBI-977302|ensembl:ENSP00000368752|ensembl:ENSP00000399376|ensembl:ENSP00000411599|ensembl:ENSP00000415284|uniprotkb:O60489|uniprotkb:P78446|uniprotkb:Q15216|uniprotkb:Q15221|uniprotkb:Q27H91|uniprotkb:Q8TBG0|uniprotkb:Q96E70|uniprotkb:Q9UP19|uniprotkb:Q5QPB4 psi-mi:b3xyc5_sollc(display_long) psi-mi:prio_human(display_long)|uniprotkb:PrP27-30(gene name synonym)|uniprotkb:PrP33-35C(gene name synonym)|uniprotkb:ASCR(gene name synonym)|uniprotkb:PRNP(gene name)|psi-mi:PRNP(display_short)|uniprotkb:PRIP(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:ALTPRP(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035690"|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|ensembl:ENSG00000171867(gene)|ensembl:ENST00000379440(transcript)|ensembl:ENST00000424424(transcript)|ensembl:ENST00000430350(transcript)|ensembl:ENST00000457586(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007049"(cell cycle)|go:"GO:0007611"(learning or memory)|go:"GO:0007616"(long-term memory)|go:"GO:0009986"(cell surface)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016234"(inclusion body)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031648"(protein destabilization)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098794"(postsynapse)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:0045121"(membrane raft)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903135"(cupric ion binding)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000817(Prion protein)|interpro:IPR022416|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|interpro:IPR025860|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|interpro:IPR036924|mint:P04156|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051087"(chaperone binding)|rcsb pdb:1E1G|rcsb pdb:1E1J|rcsb pdb:1E1P|rcsb pdb:1E1S|rcsb pdb:1E1U|rcsb pdb:1E1W|rcsb pdb:1FKC|rcsb pdb:1FO7|rcsb pdb:1H0L|rcsb pdb:1HJM|rcsb pdb:1HJN|rcsb pdb:1I4M|rcsb pdb:1OEH|rcsb pdb:1OEI|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1QLX|rcsb pdb:1QLZ|rcsb pdb:1QM0|rcsb pdb:1QM1|rcsb pdb:1QM2|rcsb pdb:1QM3|rcsb pdb:2IV4|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|rcsb pdb:2IV5|rcsb pdb:2IV6|rcsb pdb:2K1D|rcsb pdb:2KUN|rcsb pdb:2LBG|rcsb pdb:2LEJ|rcsb pdb:2LFT|rcsb pdb:2LSB|rcsb pdb:2LV1|rcsb pdb:2M8T|rcsb pdb:2OL9|rcsb pdb:2W9E|rcsb pdb:3HAF|rcsb pdb:3HAK|rcsb pdb:3HEQ|rcsb pdb:3HER|rcsb pdb:3HES|rcsb pdb:3HJ5|rcsb pdb:3HJX|rcsb pdb:3MD4|rcsb pdb:3MD5|rcsb pdb:3NHC|rcsb pdb:3NHD|rcsb pdb:3NVF|rcsb pdb:4DGI|rcsb pdb:4E1H|rcsb pdb:4E1I|rcsb pdb:4KML|rcsb pdb:4N9O|rcsb pdb:5L6R|rcsb pdb:5YJ4|rcsb pdb:5YJ5|rcsb pdb:6DU9|rcsb pdb:6LNI|rcsb pdb:6PQ5|rcsb pdb:6PQA|rcsb pdb:6SUZ|rcsb pdb:6SV2|rcsb pdb:6UUR|reactome:R-HSA-419037|reactome:R-HSA-9609523|refseq:NP_000302.1|refseq:NP_001073590.1|refseq:NP_001073591.1|refseq:NP_001073592.1|refseq:NP_898902.1|refseq:NP_001258490.1|dip:DIP-29933N psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:O9dYBDKthE5DdgePny2xsDYzb989606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P11279 intact:EBI-4319310 intact:EBI-2805407|uniprotkb:B4DWL3|ensembl:ENSP00000333298|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40 psi-mi:b3xyc5_sollc(display_long) psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) ensembl:ENSG00000185896(gene)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0044754"(autolysosome)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENST00000332556(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P11279|reactome:R-HSA-6798695|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|refseq:NP_005552.3|dip:DIP-44670N psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:O15118 intact:EBI-4319310 intact:EBI-2368710|uniprotkb:Q9P130|uniprotkb:B4DET3|ensembl:ENSP00000269228 psi-mi:b3xyc5_sollc(display_long) psi-mi:npc1_human(display_long)|uniprotkb:NPC1(gene name)|psi-mi:NPC1(display_short)|uniprotkb:Niemann-Pick C1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_000262.2|dip:DIP-53217N|ensembl:ENSG00000141458(gene)|ensembl:ENST00000269228(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0010467"(gene expression)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045121"(membrane raft)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR004765(Niemann-Pick C type protein)|interpro:IPR032190|rcsb pdb:3GKH|rcsb pdb:3GKI|rcsb pdb:3GKJ|rcsb pdb:3JD8|rcsb pdb:5F18|rcsb pdb:5F1B|rcsb pdb:5HNS|rcsb pdb:5JNX|rcsb pdb:5KWY|rcsb pdb:5U73|rcsb pdb:5U74|rcsb pdb:6UOX|rcsb pdb:6W5R|rcsb pdb:6W5S|rcsb pdb:6W5T|rcsb pdb:6W5U|rcsb pdb:6W5V|reactome:R-HSA-8964038 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:3kG4MGzeShC2D5FsPoZZm1lEGlk9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:O60637 intact:EBI-4319310 intact:EBI-750541|uniprotkb:Q9BW22|uniprotkb:Q9NVX9|uniprotkb:B3KQQ2|uniprotkb:B4DP19|uniprotkb:A6NEH4|ensembl:ENSP00000267970 psi-mi:b3xyc5_sollc(display_long) psi-mi:tsn3_human(display_long)|uniprotkb:Transmembrane 4 superfamily member 8(gene name synonym)|uniprotkb:Tetraspanin TM4-A(gene name synonym)|uniprotkb:TSPAN3(gene name)|psi-mi:TSPAN3(display_short)|uniprotkb:TM4SF8(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_005715.1|refseq:NP_944492.1|refseq:NP_001161884.1|ensembl:ENSG00000140391(gene)|ensembl:ENST00000267970(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:O60637 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:oMRwE4ZFECo1lF/A1S+P1db6pFk9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P30825 intact:EBI-4319310 intact:EBI-4289564|uniprotkb:Q5JR50|ensembl:ENSP00000370128 psi-mi:b3xyc5_sollc(display_long) psi-mi:sl7a1_human(display_long)|uniprotkb:SLC7A1(gene name)|psi-mi:SLC7A1(display_short)|uniprotkb:ATRC1(gene name synonym)|uniprotkb:ERR(gene name synonym)|uniprotkb:REC1L(gene name synonym)|uniprotkb:Ecotropic retroviral leukemia receptor homolog(gene name synonym)|uniprotkb:Ecotropic retrovirus receptor homolog(gene name synonym)|uniprotkb:Solute carrier family 7 member 1(gene name synonym)|uniprotkb:System Y+ basic amino acid transporter(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_003036.1|ensembl:ENSG00000139514(gene)|ensembl:ENST00000380752(transcript)|go:"GO:0000064"(L-ornithine transmembrane transporter activity)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015174"(basic amino acid transmembrane transporter activity)|go:"GO:0015181"|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015807"(L-amino acid transport)|go:"GO:0015819"(lysine transport)|go:"GO:0015822"(ornithine transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|go:"GO:0089718"(amino acid import across plasma membrane)|go:"GO:0097638"(L-arginine import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903352"(L-ornithine transmembrane transport)|go:"GO:1903810"(L-histidine import across plasma membrane)|go:"GO:1903826"(L-arginine transmembrane transport)|go:"GO:1990822"(basic amino acid transmembrane transport)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004755(Cationic amino acid transport permease)|interpro:IPR029485|reactome:R-HSA-352230|refseq:XP_005266564.1|refseq:XP_016876205.1 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:0Y2qLKGZJkRCQmCro2MEGj6tEr49606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:O60487 intact:EBI-4319310 intact:EBI-3906725|uniprotkb:A8K2R1|ensembl:ENSP00000278937|ensembl:ENSP00000408362 psi-mi:b3xyc5_sollc(display_long) psi-mi:mpzl2_human(display_long)|uniprotkb:MPZL2(gene name)|psi-mi:MPZL2(display_short)|uniprotkb:EVA(gene name synonym)|uniprotkb:EVA1(gene name synonym)|uniprotkb:Epithelial V-like antigen 1(gene name synonym)|uniprotkb:UNQ606/PRO1192(orf name) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_005788.1|refseq:NP_658911.1|ensembl:ENSG00000149573(gene)|ensembl:ENST00000278937(transcript)|ensembl:ENST00000438295(transcript)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000920(Myelin P0 protein)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029863|interpro:IPR036179 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:YQHXvM5xiVw8HV97MnJ67T4/D5E9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q16563 intact:EBI-4319310 intact:EBI-2800683|uniprotkb:A4D0R2|uniprotkb:Q96AR8|ensembl:ENSP00000011473 psi-mi:b3xyc5_sollc(display_long) psi-mi:sypl1_human(display_long)|uniprotkb:SYPL(gene name synonym)|uniprotkb:Pantophysin(gene name synonym)|uniprotkb:SYPL1(gene name)|psi-mi:SYPL1(display_short) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_006745.1|refseq:NP_874384.1|ensembl:ENSG00000008282(gene)|ensembl:ENST00000011473(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR008253(Marvel) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:kw4EuKqd6PhotpKiicCjB99ZZCY9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q6YBV0 intact:EBI-4319310 intact:EBI-4320098|uniprotkb:Q86X30|uniprotkb:Q8IVM5|uniprotkb:Q8N8S6|ensembl:ENSP00000317382 psi-mi:b3xyc5_sollc(display_long) psi-mi:s36a4_human(display_long)|uniprotkb:SLC36A4(gene name)|psi-mi:SLC36A4(display_short)|uniprotkb:PAT4(gene name synonym)|uniprotkb:Solute carrier family 36 member 4(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_689526.2|refseq:NP_001273068.1|refseq:XP_016872665.1|ensembl:ENSG00000180773(gene)|ensembl:ENST00000326402(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005886"(plasma membrane)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0015196"(L-tryptophan transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015808"(L-alanine transport)|go:"GO:0015824"(proline transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:1904271"(L-proline import across plasma membrane)|go:"GO:1904556"(L-tryptophan transmembrane transport)|interpro:IPR013057(Amino acid transporter, transmembrane)|reactome:R-HSA-352230|reactome:R-HSA-71240 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:5V6+EW+kAVgYyfJG/ZZ1wdTvFSE9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q68CP4 intact:EBI-4319310 intact:EBI-2867901|uniprotkb:B4E2V0 psi-mi:b3xyc5_sollc(display_long) psi-mi:hgnat_human(display_long)|uniprotkb:HGSNAT(gene name)|psi-mi:HGSNAT(display_short)|uniprotkb:TMEM76(gene name synonym)|uniprotkb:Transmembrane protein 76(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_689632.2|interpro:IPR012429(Protein of unknown function DUF1624)|interpro:IPR040208|mint:Q68CP4|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007041"(lysosomal transport)|go:"GO:0015019"(heparan-alpha-glucosaminide N-acetyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0070821"(tertiary granule membrane)|reactome:R-HSA-2024096|reactome:R-HSA-2206291|reactome:R-HSA-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:NPw8nihV4yj9Am0bzJzeQdHpntg9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q12884 intact:EBI-4319310 intact:EBI-4319803|uniprotkb:O00199|uniprotkb:Q53TP5|uniprotkb:Q86Z29|uniprotkb:Q99998|uniprotkb:Q9UID4|ensembl:ENSP00000188790 psi-mi:b3xyc5_sollc(display_long) psi-mi:sepr_human(display_long)|uniprotkb:Integral membrane serine protease(gene name synonym)|uniprotkb:FAP(gene name)|psi-mi:FAP(display_short)|uniprotkb:170 kDa melanoma membrane-bound gelatinase(gene name synonym)|uniprotkb:Fibroblast activation protein alpha(gene name synonym)|uniprotkb:Dipeptidyl peptidase FAP(gene name synonym)|uniprotkb:Gelatine degradation protease FAP(gene name synonym)|uniprotkb:Post-proline cleaving enzyme(gene name synonym)|uniprotkb:Serine integral membrane protease(gene name synonym)|uniprotkb:Surface-expressed protease(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_004451.2|refseq:NP_001278736.1|ensembl:ENSG00000078098(gene)|ensembl:ENST00000188790(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002020"(protease binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008239"(dipeptidyl-peptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051917"(regulation of fibrinolysis)|go:"GO:0060244"(negative regulation of cell proliferation involved in contact inhibition)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1902362"(melanocyte apoptotic process)|go:"GO:1903054"(negative regulation of extracellular matrix organization)|go:"GO:1905368"(peptidase complex)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002469(Peptidase S9B, dipeptidylpeptidase IV N-terminal)|interpro:IPR002471(Peptidase S9, serine active site)|interpro:IPR029058|interpro:IPR031245|rcsb pdb:1Z68|rcsb pdb:6Y0F|go:"GO:0010716"(negative regulation of extracellular matrix disassembly) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:EP0sQlmVlm/H+15legbkc2IvEeg9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P54849 intact:EBI-4319310 intact:EBI-4319440|uniprotkb:B2R5N1|uniprotkb:O00681|uniprotkb:Q13481|uniprotkb:Q13834|uniprotkb:B4DRR1|ensembl:ENSP00000256951 psi-mi:b3xyc5_sollc(display_long) psi-mi:emp1_human(display_long)|uniprotkb:EMP1(gene name)|psi-mi:EMP1(display_short)|uniprotkb:B4B(gene name synonym)|uniprotkb:TMP(gene name synonym)|uniprotkb:CL-20(gene name synonym)|uniprotkb:Protein B4B(gene name synonym)|uniprotkb:Tumor-associated membrane protein(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001414.1|ensembl:ENSG00000134531(gene)|ensembl:ENST00000256951(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003932(Epithelial membrane protein EMP-1)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:HBEmCEoWn+QsCev1GLzAAKPsQGA9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q9P2C4 intact:EBI-4319310 intact:EBI-4320050|uniprotkb:Q5VTU1|ensembl:ENSP00000356057 psi-mi:b3xyc5_sollc(display_long) psi-mi:tm181_human(display_long)|uniprotkb:TMEM181(gene name)|psi-mi:TMEM181(display_short)|uniprotkb:GPR178(gene name synonym)|uniprotkb:KIAA1423(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_065874.1|ensembl:ENSG00000146433(gene)|ensembl:ENST00000367090(transcript)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040416 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:NWBUU8Jqn2co5E4+FAWp+BcE7IM9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q14108 intact:EBI-4319310 intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896 psi-mi:b3xyc5_sollc(display_long) psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P08195 intact:EBI-4319310 intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122 psi-mi:b3xyc5_sollc(display_long) psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q14627 intact:EBI-4319310 intact:EBI-4320063|uniprotkb:A8K7E2|uniprotkb:O00667|ensembl:ENSP00000243213|ensembl:ENSP00000361004 psi-mi:b3xyc5_sollc(display_long) psi-mi:i13r2_human(display_long)|uniprotkb:IL13RA2(gene name)|psi-mi:IL13RA2(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:Interleukin-13-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_000631.1|ensembl:ENSG00000123496(gene)|ensembl:ENST00000243213(transcript)|ensembl:ENST00000371936(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:3LB6|reactome:R-HSA-6785807|dip:DIP-3340N psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:LItbTlLuFXGhjC4PVCIW9aeBRZk9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q8NBI5 intact:EBI-4319310 intact:EBI-2855542|uniprotkb:Q9NSS4|uniprotkb:B4DNR8|uniprotkb:E7EQD2|ensembl:ENSP00000337561|ensembl:ENSP00000378555|ensembl:ENSP00000378556|ensembl:ENSP00000436254 psi-mi:b3xyc5_sollc(display_long) psi-mi:s43a3_human(display_long)|uniprotkb:SLC43A3(gene name)|psi-mi:SLC43A3(display_short)|uniprotkb:Protein FOAP-13(gene name synonym)|uniprotkb:PSEC0252(orf name) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_054815.2|refseq:NP_060081.1|refseq:NP_955361.1|refseq:NP_001265130.1|refseq:NP_001265135.1|ensembl:ENSG00000134802(gene)|ensembl:ENST00000352187(transcript)|ensembl:ENST00000395123(transcript)|ensembl:ENST00000395124(transcript)|ensembl:ENST00000529554(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR027197|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:REQvBGxZEQ5d+FuiyZjxNNKtY9A9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q12913 intact:EBI-4319310 intact:EBI-2264500|uniprotkb:Q9UDA9|uniprotkb:Q15255|uniprotkb:Q8NHM2|uniprotkb:Q6P4H4|ensembl:ENSP00000400010 psi-mi:b3xyc5_sollc(display_long) psi-mi:ptprj_human(display_long)|uniprotkb:PTPRJ(gene name)|psi-mi:PTPRJ(display_short)|uniprotkb:DEP1(gene name synonym)|uniprotkb:HPTP eta(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type J(gene name synonym)|uniprotkb:Density-enhanced phosphatase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_002834.3|refseq:NP_001091973.1|go:"GO:0070097"(delta-catenin binding)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:Q12913|rcsb pdb:2CFV|rcsb pdb:2DLE|rcsb pdb:2NZ6|reactome:R-HSA-202427|reactome:R-HSA-6798695|reactome:R-HSA-6807004|ensembl:ENSG00000149177(gene)|ensembl:ENST00000418331(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060242"(contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0035579"(specific granule membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0006470"(protein dephosphorylation)|reactome:R-HSA-9706369 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:tGsQm2S/SSUjbnV/WwKSb4rPz/49606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q99808 intact:EBI-4319310 intact:EBI-347907|uniprotkb:Q5T9W9|uniprotkb:B3KQV7|uniprotkb:Q9UJY2|uniprotkb:B3KQY5|ensembl:ENSP00000360773|ensembl:ENSP00000360778|ensembl:ENSP00000360789|ensembl:ENSP00000360820|ensembl:ENSP00000377427|ensembl:ENSP00000498610|ensembl:ENSP00000498747|ensembl:ENSP00000499107 psi-mi:b3xyc5_sollc(display_long) psi-mi:s29a1_human(display_long)|uniprotkb:SLC29A1(gene name)|psi-mi:SLC29A1(display_short)|uniprotkb:ENT1(gene name synonym)|uniprotkb:Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter(gene name synonym)|uniprotkb:Nucleoside transporter, es-type(gene name synonym)|uniprotkb:Solute carrier family 29 member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001291391.1|refseq:NP_001291392.1|refseq:NP_001291394.1|refseq:NP_001291395.1|refseq:NP_001071643.1|refseq:NP_001071645.1|refseq:XP_005248935.1|refseq:XP_005248936.1|refseq:XP_005248937.1|refseq:XP_005248938.1|refseq:XP_005248939.1|ensembl:ENSG00000112759(gene)|ensembl:ENST00000371708(transcript)|ensembl:ENST00000371713(transcript)|ensembl:ENST00000371724(transcript)|ensembl:ENST00000371755(transcript)|ensembl:ENST00000393844(transcript)|ensembl:ENST00000651428(transcript)|ensembl:ENST00000652453(transcript)|ensembl:ENST00000652680(transcript)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007595"(lactation)|go:"GO:0015211"(purine nucleoside transmembrane transporter activity)|go:"GO:0015213"(uridine transmembrane transporter activity)|go:"GO:0015858"(nucleoside transport)|go:"GO:0015860"(purine nucleoside transmembrane transport)|go:"GO:0015862"(uridine transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030431"(sleep)|go:"GO:0032238"(adenosine transport)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072531"(pyrimidine-containing compound transmembrane transport)|go:"GO:0080122"(AMP transmembrane transporter activity)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901642"(nucleoside transmembrane transport)|interpro:IPR002259(Delayed-early response protein/equilibrative nucleoside transporter)|interpro:IPR030195|interpro:IPR034764|interpro:IPR036259|mint:Q99808|rcsb pdb:6OB6|go:"GO:0001504"(neurotransmitter uptake)|rcsb pdb:6OB7|reactome:R-HSA-83936|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005337"(nucleoside transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:whdAbkkAMjI+UBbbf52FncxXtb09606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P55011 intact:EBI-4319310 intact:EBI-2801449|uniprotkb:Q8WWH7|uniprotkb:Q8N713|intact:EBI-28983018|ensembl:ENSP00000262461 psi-mi:b3xyc5_sollc(display_long) psi-mi:s12a2_human(display_long)|uniprotkb:NKCC1(gene name synonym)|uniprotkb:Basolateral Na-K-Cl symporter(gene name synonym)|uniprotkb:SLC12A2(gene name)|psi-mi:SLC12A2(display_short)|uniprotkb:"Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2"(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) ensembl:ENSP00000262461|ensembl:ENST00000343225|ensembl:ENSP00000340878|refseq:NP_001037.1|ensembl:ENSG00000064651(gene)|ensembl:ENST00000262461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0008511"("sodium:potassium:chloride symporter activity")|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015377"("cation:chloride symporter activity")|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0015696"|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0044298"(cell body membrane)|go:"GO:0045795"(positive regulation of cell volume)|go:"GO:0046873"(metal ion transmembrane transporter activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0061044"(negative regulation of vascular wound healing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070634"(transepithelial ammonium transport)|go:"GO:0071944"(cell periphery)|go:"GO:0098658"(inorganic anion import across plasma membrane)|go:"GO:0098659"(inorganic cation import across plasma membrane)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904450"(positive regulation of aspartate secretion)|go:"GO:1904464"(regulation of matrix metallopeptidase secretion)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:0042995"(cell projection)|interpro:IPR002444(Na-K-Cl co-transporter 1)|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004842(Na-K-Cl cotransporter superfamily)|interpro:IPR013612(Amino acid permease N-terminal)|interpro:IPR018491|mint:P55011|rcsb pdb:6PZT|rcsb pdb:7D10|reactome:R-HSA-426117|interpro:IPR002443(Na-K-Cl co-transporter)|dip:DIP-43979N psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:DJ/f5e8b/aBlnCcWYxYUa/mcoFY9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P13598 intact:EBI-4319310 intact:EBI-2806056|ensembl:ENSP00000464665|uniprotkb:Q14600|ensembl:ENSP00000388666|ensembl:ENSP00000392634|ensembl:ENSP00000415283|ensembl:ENSP00000462579 psi-mi:b3xyc5_sollc(display_long) psi-mi:icam2_human(display_long)|uniprotkb:ICAM2(gene name)|psi-mi:ICAM2(display_short) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) ensembl:ENST00000412356(transcript)|ensembl:ENST00000418105(transcript)|ensembl:ENST00000449662(transcript)|ensembl:ENST00000579687(transcript)|ensembl:ENST00000579788(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR003988(Intercellular adhesion molecule)|interpro:IPR013768(Intercellular adhesion molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015653(Intercellular adhesion molecule 2)|interpro:IPR036179|rcsb pdb:1ZXQ|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-5621575|refseq:NP_000864.2|refseq:NP_001093256.1|refseq:NP_001093257.1|refseq:NP_001093258.1|refseq:NP_001093259.1|ensembl:ENSG00000108622(gene) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:46FxUe9wv2WIelobimN/4k+qSS89606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q8TCT8 intact:EBI-4319310 intact:EBI-750784|uniprotkb:Q8TAW1|uniprotkb:Q96SZ8|uniprotkb:B2RDS0|ensembl:ENSP00000261854 psi-mi:b3xyc5_sollc(display_long) psi-mi:spp2a_human(display_long)|uniprotkb:Intramembrane protease 3(gene name synonym)|uniprotkb:Presenilin-like protein 2(gene name synonym)|uniprotkb:SPPL2A(gene name)|psi-mi:SPPL2A(display_short)|uniprotkb:PSL2(gene name synonym)|uniprotkb:PSEC0147(orf name)|uniprotkb:IMP3(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_116191.2|ensembl:ENSG00000138600(gene)|ensembl:ENST00000261854(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0042500"(aspartic endopeptidase activity, intramembrane cleaving)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050776"(regulation of immune response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR003137(Protease-associated PA)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR007369(Peptidase A22B, signal peptide peptidase)|reactome:R-HSA-5357905 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:EUCJ0AkhCnUcMjDt09aE75qnam49606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P54709 intact:EBI-4319310 intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371 psi-mi:b3xyc5_sollc(display_long) psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q9NY35 intact:EBI-4319310 intact:EBI-4319704|uniprotkb:B3KQR1|uniprotkb:D3DN36|uniprotkb:Q502Y8|uniprotkb:Q6UVX2|uniprotkb:Q9BUZ9|uniprotkb:Q9NZZ5|uniprotkb:Q9Y4S9|uniprotkb:F2Z2D9|ensembl:ENSP00000340247|ensembl:ENSP00000377734|ensembl:ENSP00000377739|ensembl:ENSP00000421226|ensembl:ENSP00000423590|ensembl:ENSP00000426869 psi-mi:b3xyc5_sollc(display_long) psi-mi:cldn1_human(display_long)|uniprotkb:CLDND1(gene name)|psi-mi:CLDND1(display_short)|uniprotkb:C3orf4(gene name synonym)|uniprotkb:Membrane protein GENX-3745(gene name synonym)|uniprotkb:HSPC174(orf name)|uniprotkb:PSEC0054(orf name)|uniprotkb:UNQ2511/PRO6000(orf name) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001035271.1|refseq:NP_001035272.1|refseq:NP_001035273.1|refseq:NP_001035289.1|refseq:NP_063948.1|refseq:NP_001035290.1|ensembl:ENSG00000080822(gene)|ensembl:ENST00000341181(transcript)|ensembl:ENST00000394180(transcript)|ensembl:ENST00000394185(transcript)|ensembl:ENST00000503004(transcript)|ensembl:ENST00000510545(transcript)|ensembl:ENST00000513287(transcript)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|mint:Q9NY35|interpro:IPR042356 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:CNmeJrYJHY7m8TRdvFpUcASQujk9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q9H813 intact:EBI-4319310 intact:EBI-4319734|uniprotkb:Q6IA87|uniprotkb:Q9NV85|uniprotkb:B7Z4D6|ensembl:ENSP00000261455 psi-mi:b3xyc5_sollc(display_long) psi-mi:pacc1_human(display_long)|uniprotkb:PACC1(gene name)|psi-mi:PACC1(display_short)|uniprotkb:C1orf75(gene name synonym)|uniprotkb:TMEM206(gene name synonym)|uniprotkb:Transmembrane protein 206(gene name synonym)|uniprotkb:Acid-sensitive outwardly-rectifying anion channel(gene name synonym)|uniprotkb:Proton-activated outwardly rectifying anion channel(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001185791.1|refseq:NP_060722.2|ensembl:ENST00000261455(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0009986"(cell surface)|go:"GO:0034707"(chloride channel complex)|go:"GO:0061797"(pH-gated chloride channel activity)|interpro:IPR029366|rcsb pdb:7JNA|rcsb pdb:7JNC|ensembl:ENSG00000065600(gene) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:BS+RtL4iqT3EeFfU3tXira3KOQ89606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P25942 intact:EBI-4319310 intact:EBI-525714|intact:EBI-1056393|uniprotkb:Q53GN5|uniprotkb:Q5JY15|uniprotkb:Q5U007|uniprotkb:Q7M4Q8|uniprotkb:Q86YK5|uniprotkb:Q9BYU0|uniprotkb:E1P5S9|ensembl:ENSP00000361359 psi-mi:b3xyc5_sollc(display_long) psi-mi:tnr5_human(display_long)|uniprotkb:CD40L receptor(gene name synonym)|uniprotkb:B-cell surface antigen CD40(gene name synonym)|uniprotkb:Bp50(gene name synonym)|uniprotkb:CDw40(gene name synonym)|uniprotkb:CD40(gene name)|psi-mi:CD40(display_short)|uniprotkb:TNFRSF5(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001241.1|refseq:NP_690593.1|dip:DIP-3014N|refseq:NP_001289682.1|refseq:NP_001309351.1|ensembl:ENSG00000101017(gene)|ensembl:ENST00000372285(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002768"(immune response-regulating cell surface receptor signaling pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030168"(platelet activation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0036018"(cellular response to erythropoietin)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043196"(varicosity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:1901652"(response to peptide)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR020435|interpro:IPR034021|rcsb pdb:1CDF|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1FLL|rcsb pdb:1LB6|rcsb pdb:3QD6|rcsb pdb:5DMI|rcsb pdb:5DMJ|rcsb pdb:5IHL|rcsb pdb:6FAX|rcsb pdb:6PE8|rcsb pdb:6PE9|reactome:R-HSA-198933|reactome:R-HSA-5668541|reactome:R-HSA-5676594 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:hkjl1/jpI7bR4QFUWQKUl0CEZQE9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q8WWB7 intact:EBI-4319310 intact:EBI-2874630|uniprotkb:B4DJN4|uniprotkb:A6NH16|uniprotkb:Q8IV07|uniprotkb:Q6UX96|uniprotkb:Q5SZX4|uniprotkb:Q96F65|ensembl:ENSP00000354553|ensembl:ENSP00000497576 psi-mi:b3xyc5_sollc(display_long) psi-mi:glmp_human(display_long)|uniprotkb:GLMP(gene name)|psi-mi:GLMP(display_short)|uniprotkb:C1orf85(gene name synonym)|uniprotkb:Lysosomal protein NCU-G1(gene name synonym)|uniprotkb:PSEC0030(orf name)|uniprotkb:UNQ2553/PRO6182(orf name) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_653181.1|refseq:NP_001243538.1|ensembl:ENSG00000198715(gene)|ensembl:ENST00000362007(transcript)|ensembl:ENST00000647767(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0061462"(protein localization to lysosome)|interpro:IPR029382 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:v5KmNg/5Fq/5vg/vzWtGUMD9q109606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q9UIQ6 intact:EBI-4319310 intact:EBI-2805360|uniprotkb:O00769|uniprotkb:Q9TNQ2|uniprotkb:Q9TNQ3|uniprotkb:Q9UIQ7|uniprotkb:Q59H76|uniprotkb:Q15145|ensembl:ENSP00000231368 psi-mi:b3xyc5_sollc(display_long) psi-mi:lcap_human(display_long)|uniprotkb:OTASE(gene name synonym)|uniprotkb:Oxytocinase(gene name synonym)|uniprotkb:Insulin-regulated membrane aminopeptidase(gene name synonym)|uniprotkb:Insulin-responsive aminopeptidase(gene name synonym)|uniprotkb:Placental leucine aminopeptidase(gene name synonym)|uniprotkb:LNPEP(gene name)|psi-mi:LNPEP(display_short) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR034017|interpro:IPR042097|rcsb pdb:4P8Q|go:"GO:0006508"(proteolysis)|rcsb pdb:4PJ6|rcsb pdb:4Z7I|rcsb pdb:5C97|rcsb pdb:5JHQ|rcsb pdb:5MJ6|reactome:R-HSA-1236977|reactome:R-HSA-1445148|reactome:R-HSA-983168|ensembl:ENSG00000113441(gene)|ensembl:ENST00000231368(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|refseq:NP_005566.2|refseq:NP_787116.2 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:IOU7GW8f6aBYAjIUQXFKbU5Hqkw9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P54852 intact:EBI-4319310 intact:EBI-3907816|uniprotkb:Q6FH01|ensembl:ENSP00000270221|ensembl:ENSP00000469194 psi-mi:b3xyc5_sollc(display_long) psi-mi:emp3_human(display_long)|uniprotkb:EMP3(gene name)|psi-mi:EMP3(display_short)|uniprotkb:YMP(gene name synonym)|uniprotkb:Hematopoietic neural membrane protein 1(gene name synonym)|uniprotkb:Protein YMP(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:XP_011524907.1|refseq:NP_001416.1|refseq:NP_001300834.1|ensembl:ENSG00000142227(gene)|ensembl:ENST00000270221(transcript)|ensembl:ENST00000597279(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003934(Epithelial membrane protein EMP-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:NXSoiRWNSe4m3IqmN64fUaGxFLA9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q08722 intact:EBI-4319310 intact:EBI-1268321|uniprotkb:Q53Y71|uniprotkb:Q96A60|uniprotkb:A8K198|uniprotkb:D3DN59|ensembl:ENSP00000355361 psi-mi:b3xyc5_sollc(display_long) psi-mi:cd47_human(display_long)|uniprotkb:CD47(gene name)|psi-mi:CD47(display_short)|uniprotkb:MER6(gene name synonym)|uniprotkb:Integrin-associated protein(gene name synonym)|uniprotkb:Antigenic surface determinant protein OA3(gene name synonym)|uniprotkb:Protein MER6(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001768.1|refseq:NP_942088.1|dip:DIP-39948N|ensembl:ENSG00000196776(gene)|ensembl:ENST00000361309(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032653"(regulation of interleukin-10 production)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904669"(ATP export)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:2000439"(positive regulation of monocyte extravasation)|interpro:IPR006704(CD47 integrin associated protein)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013147(CD47 transmembrane)|interpro:IPR013270(CD47 immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037805|rcsb pdb:2JJS|rcsb pdb:2JJT|rcsb pdb:2VSC|rcsb pdb:4CMM|rcsb pdb:4KJY|rcsb pdb:5IWL|rcsb pdb:5TZ2|rcsb pdb:5TZT|rcsb pdb:5TZU|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-391160|reactome:R-HSA-6798695|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:2hhmwvfeDFe7KHXzsBOJkjo2pjk9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:O43688 intact:EBI-4319310 intact:EBI-722017|uniprotkb:A6NLV0|uniprotkb:E9PAY8|ensembl:ENSP00000388565 psi-mi:b3xyc5_sollc(display_long) psi-mi:plpp2_human(display_long)|uniprotkb:PLPP2(gene name)|psi-mi:PLPP2(display_short)|uniprotkb:LPP2(gene name synonym)|uniprotkb:Lipid phosphate phosphohydrolase 2(gene name synonym)|uniprotkb:PAP2-gamma(gene name synonym)|uniprotkb:PPAP2C(gene name synonym)|uniprotkb:Phosphatidate phosphohydrolase type 2c(gene name synonym)|uniprotkb:Phosphatidic acid phosphatase 2c(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_003703.1|refseq:NP_803545.1|refseq:NP_808211.1|go:"GO:0006670"(sphingosine metabolic process)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042392"(sphingosine-1-phosphate phosphatase activity)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0046839"(phospholipid dephosphorylation)|go:"GO:0106235"(ceramide-1-phosphate phosphatase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR028674|interpro:IPR036938|interpro:IPR043216|reactome:R-HSA-1660661|ensembl:ENSG00000141934(gene)|ensembl:ENST00000434325(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006644"(phospholipid metabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:L/wCkwuIB6W9RPUoojQrmU9U8tY9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P35613 intact:EBI-4319310 intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769 psi-mi:b3xyc5_sollc(display_long) psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|refseq:XP_016882662.1|dip:DIP-50310N|ensembl:ENSG00000172270(gene)|ensembl:ENST00000333511(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005537"(mannose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007566"(embryo implantation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046697"(decidualization)|go:"GO:0051591"(response to cAMP)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268|rcsb pdb:3QR2 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q9UIG8 intact:EBI-4319310 intact:EBI-4319406|uniprotkb:A8K4A7|uniprotkb:B3KPY5|uniprotkb:B3KUR7|uniprotkb:C6G486|uniprotkb:Q9BW73|uniprotkb:Q9GZV2|ensembl:ENSP00000320634 psi-mi:b3xyc5_sollc(display_long) psi-mi:so3a1_human(display_long)|uniprotkb:SLCO3A1(gene name)|psi-mi:SLCO3A1(display_short)|uniprotkb:OATP3A1(gene name synonym)|uniprotkb:OATPD(gene name synonym)|uniprotkb:SLC21A11(gene name synonym)|uniprotkb:Organic anion transporter polypeptide-related protein 3(gene name synonym)|uniprotkb:Organic anion-transporting polypeptide D(gene name synonym)|uniprotkb:PGE1 transporter(gene name synonym)|uniprotkb:Sodium-independent organic anion transporter D(gene name synonym)|uniprotkb:Solute carrier family 21 member 11(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001138516.1|refseq:NP_037404.2|ensembl:ENSG00000176463(gene)|ensembl:ENST00000318445(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015347"(sodium-independent organic anion transmembrane transporter activity)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0043252"(sodium-independent organic anion transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR004156(Organic anion transporter polypeptide OATP)|interpro:IPR036058|interpro:IPR036259|reactome:R-HSA-879518 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:d38N8M1fUCE4KjPw57e05g2SMvg9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q9Y639 intact:EBI-4319310 intact:EBI-4319465|uniprotkb:B7Z4D3|uniprotkb:B7ZLL2|uniprotkb:Q17R52|uniprotkb:Q59EJ9|uniprotkb:Q6NVX7|uniprotkb:Q9Y640|uniprotkb:B2RAL7|ensembl:ENSP00000290401 psi-mi:b3xyc5_sollc(display_long) psi-mi:nptn_human(display_long)|uniprotkb:NPTN(gene name)|psi-mi:NPTN(display_short)|uniprotkb:SDFR1(gene name synonym)|uniprotkb:SDR1(gene name synonym)|uniprotkb:Stromal cell-derived receptor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001154835.1|refseq:NP_001154836.1|refseq:NP_036560.1|refseq:NP_059429.1|ensembl:ENSG00000156642(gene)|ensembl:ENST00000345330(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007411"(axon guidance)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099557"(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902683"(regulation of receptor localization to synapse)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904861"(excitatory synapse assembly)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR027112|interpro:IPR036179|interpro:IPR043204|mint:Q9Y639|rcsb pdb:6A69|reactome:R-HSA-977443 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:0q2qm01VJXRQz1/RXdtQr7wUj3A9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:Q8NBN3 intact:EBI-4319310 intact:EBI-2687855|uniprotkb:Q9P103|uniprotkb:Q9Y3Y7|uniprotkb:Q9BS46|uniprotkb:Q6NT77|uniprotkb:Q8NCA4|ensembl:ENSP00000374484 psi-mi:b3xyc5_sollc(display_long) psi-mi:tm87a_human(display_long)|uniprotkb:PSEC0094(orf name)|uniprotkb:TMEM87A(gene name)|psi-mi:TMEM87A(display_short) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_001273416.1|refseq:NP_001103973.1|refseq:NP_056312.2|ensembl:ENSG00000103978(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR009637(Transmembrane receptor, eukaryota)|reactome:R-HSA-8980692|ensembl:ENST00000389834(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:GdHPH2U8wRKfLAAUi0q2lw4ZtCA9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B3XYC5 uniprotkb:P49281 intact:EBI-4319310 intact:EBI-4319335|uniprotkb:B3KT08|uniprotkb:O43288|uniprotkb:O60932|uniprotkb:O94801|uniprotkb:Q498Z5|uniprotkb:Q8IUD7|uniprotkb:Q96J35|uniprotkb:B4DK84|uniprotkb:F5H741|ensembl:ENSP00000446769|ensembl:ENSP00000449008|ensembl:ENSP00000494107 psi-mi:b3xyc5_sollc(display_long) psi-mi:nram2_human(display_long)|uniprotkb:SLC11A2(gene name)|psi-mi:SLC11A2(display_short)|uniprotkb:DCT1(gene name synonym)|uniprotkb:DMT1(gene name synonym)|uniprotkb:NRAMP2(gene name synonym)|uniprotkb:Divalent cation transporter 1(gene name synonym)|uniprotkb:Divalent metal transporter 1(gene name synonym)|uniprotkb:Solute carrier family 11 member 2(gene name synonym)|uniprotkb:OK/SW-cl.20(orf name) psi-mi:"MI:0096"(pull down) Wang et al. (2011) pubmed:21656680|imex:IM-16562 taxid:195583(solanum lycopersicum var. cerasiforme)|taxid:195583(Solanum lycopersicum var. cerasiforme) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319316|imex:IM-16562-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036861|interpro:IPR001002(Chitin-binding, type 1)|go:"GO:0008061"(chitin binding)|go:"GO:0030246"(carbohydrate binding) refseq:NP_000608.1|refseq:NP_001167596.1|refseq:NP_001167597.1|refseq:NP_001167598.1|refseq:NP_001167599.1|refseq:NP_001167600.1|refseq:XP_005268968.1|refseq:XP_011536706.1|refseq:XP_011536707.1|refseq:NP_001167601.1|refseq:XP_016874844.1|ensembl:ENSG00000110911(gene)|ensembl:ENST00000546636(transcript)|ensembl:ENST00000547198(transcript)|ensembl:ENST00000644495(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003032"(detection of oxygen)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006825"(copper ion transport)|go:"GO:0006826"(iron ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007611"(learning or memory)|go:"GO:0009986"(cell surface)|go:"GO:0010039"(response to iron ion)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0015094"(lead ion transmembrane transporter activity)|go:"GO:0015099"(nickel cation transmembrane transporter activity)|go:"GO:0015100"(vanadium ion transmembrane transporter activity)|go:"GO:0015295"("solute:proton symporter activity")|go:"GO:0015675"(nickel cation transport)|go:"GO:0015676"(vanadium ion transport)|go:"GO:0015692"(lead ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031526"(brush border membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033212"(iron import into cell)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0046915"(transition metal ion transmembrane transporter activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048821"(erythrocyte development)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0055037"(recycling endosome)|go:"GO:0060586"(multicellular organismal iron ion homeostasis)|go:"GO:0070574"(cadmium ion transmembrane transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070826"(paraferritin complex)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001046(Natural resistance-associated macrophage protein)|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:7BLO|rcsb pdb:7BLQ|reactome:R-HSA-425410|reactome:R-HSA-5619048|reactome:R-HSA-917937|dip:DIP-48957N psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ea.hy926)|taxid:9606(Homo sapiens EA.hy926) - 2011/08/02 2014/10/16 rogid:y2KwOpkdFsKdmgZaGJ9HpgepBBU195583 rogid:qCceFR102Qx1A3Av7qwS6Qlp4pE9606 intact-crc:B0C303F23CB93D10|rigid:qrfQ4HsOmS/khMcUlWYnGxA30KI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification)