#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BPU9 uniprotkb:Q8N4P2 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 intact:EBI-6958994|ensembl:ENSP00000386181|intact:MINT-8201091|uniprotkb:Q96NE6|uniprotkb:Q63HQ1 psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:tt30b_human(display_long)|uniprotkb:TTC30B(gene name)|psi-mi:TTC30B(display_short) psi-mi:"MI:0096"(pull down) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6959011|mint:MINT-8201211|imex:IM-15866-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2|mint:MINT-8201219(identity) ensembl:ENSG00000196659(gene)|ensembl:ENST00000408939(transcript)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005929"(cilium)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0097542"(ciliary tip)|go:"GO:0120170"(intraciliary transport particle B binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039941|reactome:R-HSA-5620924|refseq:NP_689730.2|mint:MINT-8201213(identity) - comment:mint comment:mint figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/07/21 2014/10/16 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 rogid:TCO8nxDWxu6IS5hkFa7H8XiQbyc9606 intact-crc:63682BC2F46B7900|rigid:kbyG6dsUnEi1cBfG/KlMVAdasZ4 false glutathione s tranferase tag:?-?(MINT-8201220) binding-associated region:1-364(MINT-8201216)|maltose binding protein tag:?-?(MINT-8201214) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y283 uniprotkb:Q9BPU9 intact:EBI-751472|uniprotkb:Q5W0T6|uniprotkb:Q8IVX8|uniprotkb:Q9BRB9|uniprotkb:Q9Y488|uniprotkb:Q9Y498|uniprotkb:A2A2Y2|uniprotkb:Q2NKL0|ensembl:ENSP00000262457 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 psi-mi:invs_human(display_long)|uniprotkb:Inversion of embryo turning homolog(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym)|uniprotkb:INVS(gene name)|psi-mi:INVS(display_short)|uniprotkb:INV(gene name synonym)|uniprotkb:NPHP2(gene name synonym) psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:"MI:0096"(pull down) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6959108|mint:MINT-8201254|imex:IM-15866-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055240.2|ensembl:ENSG00000119509(gene)|ensembl:ENST00000262457(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:MINT-8201282(identity) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2|mint:MINT-8201262(identity) - - comment:mint comment:homomint|figure legend:f5e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/07/21 2014/10/16 rogid:GSK8P9P5/QrqxZL6oFgyWLdQ97Y9606 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 intact-crc:9BD5903CA57DA021|rigid:5PoM0lnFPb8R7CPvpz9DqBtO5E8 false binding-associated region:1-553(MINT-8201290)|maltose binding protein tag:?-?(MINT-8201287) glutathione s tranferase tag:?-?(MINT-8201263) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y283 uniprotkb:Q8N4P2 intact:EBI-751472|uniprotkb:Q5W0T6|uniprotkb:Q8IVX8|uniprotkb:Q9BRB9|uniprotkb:Q9Y488|uniprotkb:Q9Y498|uniprotkb:A2A2Y2|uniprotkb:Q2NKL0|ensembl:ENSP00000262457 intact:EBI-6958994|ensembl:ENSP00000386181|intact:MINT-8201091|uniprotkb:Q96NE6|uniprotkb:Q63HQ1 psi-mi:invs_human(display_long)|uniprotkb:Inversion of embryo turning homolog(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym)|uniprotkb:INVS(gene name)|psi-mi:INVS(display_short)|uniprotkb:INV(gene name synonym)|uniprotkb:NPHP2(gene name synonym) psi-mi:tt30b_human(display_long)|uniprotkb:TTC30B(gene name)|psi-mi:TTC30B(display_short) psi-mi:"MI:0096"(pull down) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6959108|mint:MINT-8201254|imex:IM-15866-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055240.2|ensembl:ENSG00000119509(gene)|ensembl:ENST00000262457(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:MINT-8201282(identity) ensembl:ENSG00000196659(gene)|ensembl:ENST00000408939(transcript)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005929"(cilium)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0097542"(ciliary tip)|go:"GO:0120170"(intraciliary transport particle B binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039941|reactome:R-HSA-5620924|refseq:NP_689730.2|mint:MINT-8201256(identity) - - comment:mint comment:homomint|figure legend:f5e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/07/21 2014/10/16 rogid:GSK8P9P5/QrqxZL6oFgyWLdQ97Y9606 rogid:TCO8nxDWxu6IS5hkFa7H8XiQbyc9606 intact-crc:9BD5903CA57DA021|rigid:5PoM0lnFPb8R7CPvpz9DqBtO5E8 false binding-associated region:1-553(MINT-8201290)|maltose binding protein tag:?-?(MINT-8201287) his tag:?-?(MINT-8201257) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q62559 uniprotkb:Q8N4P2 intact:EBI-6959048|ensembl:ENSMUSP00000018002|uniprotkb:Q8BTX3|uniprotkb:Q8CI16|intact:UNK-5463358|uniprotkb:Q3TK21 intact:EBI-6958994|ensembl:ENSP00000386181|intact:MINT-8201091|uniprotkb:Q96NE6|uniprotkb:Q63HQ1 psi-mi:ift52_mouse(display_long)|uniprotkb:Ift52(gene name)|psi-mi:Ift52(display_short)|uniprotkb:Ngd5(gene name synonym)|uniprotkb:Protein NGD5(gene name synonym) psi-mi:tt30b_human(display_long)|uniprotkb:TTC30B(gene name)|psi-mi:TTC30B(display_short) psi-mi:"MI:0096"(pull down) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6959071|mint:MINT-8201226|imex:IM-15866-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006499604.1|ensembl:ENSMUSG00000017858(gene)|ensembl:ENSMUST00000018002(transcript)|go:"GO:0001841"(neural tube formation)|go:"GO:0001947"(heart looping)|interpro:IPR019196|interpro:IPR039975|rcsb pdb:5FMS|reactome:R-MMU-5610787|reactome:R-MMU-5620924|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035720"(intraciliary anterograde transport)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044292"(dendrite terminus)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0097733"(photoreceptor cell cilium)|go:"GO:0005813"(centrosome)|refseq:NP_742162.2|mint:MINT-8201228(identity) ensembl:ENSG00000196659(gene)|ensembl:ENST00000408939(transcript)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005929"(cilium)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0097542"(ciliary tip)|go:"GO:0120170"(intraciliary transport particle B binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039941|reactome:R-HSA-5620924|refseq:NP_689730.2|mint:MINT-8201234(identity) - comment:mint comment:mint figure legend:f1f|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/07/21 2014/10/16 rogid:h6XuAO1JZm86wSXpV315g1X6bzM10090 rogid:TCO8nxDWxu6IS5hkFa7H8XiQbyc9606 intact-crc:8A11AA9C7E68CF21|rigid:lHSFGWOYWVsxZJY2Qg4CrewqpFE false glutathione s tranferase tag:?-?(MINT-8201231) maltose binding protein tag:?-?(MINT-8201237)|binding-associated region:1-364(MINT-8201235) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BPU9 uniprotkb:Q9Y283 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 intact:EBI-751472|uniprotkb:Q5W0T6|uniprotkb:Q8IVX8|uniprotkb:Q9BRB9|uniprotkb:Q9Y488|uniprotkb:Q9Y498|uniprotkb:A2A2Y2|uniprotkb:Q2NKL0|ensembl:ENSP00000262457 psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:invs_human(display_long)|uniprotkb:Inversion of embryo turning homolog(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym)|uniprotkb:INVS(gene name)|psi-mi:INVS(display_short)|uniprotkb:INV(gene name synonym)|uniprotkb:NPHP2(gene name synonym) psi-mi:"MI:0096"(pull down) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6959136|mint:MINT-8201267|imex:IM-15866-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2|mint:MINT-8201275(identity) refseq:NP_055240.2|ensembl:ENSG00000119509(gene)|ensembl:ENST00000262457(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:MINT-8201269(identity) - comment:mint - figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/07/21 2014/10/16 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 rogid:GSK8P9P5/QrqxZL6oFgyWLdQ97Y9606 intact-crc:A63E783510E303ED|rigid:K/eLBYYio+h/dXMW4xpSi/ld8yc false glutathione s tranferase tag:?-?(MINT-8201276) maltose binding protein tag:?-?(MINT-8201272)|binding-associated region:1-553(MINT-8201270) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q15051 uniprotkb:P62158 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6959200|mint:MINT-8200205|imex:IM-15866-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417|mint:MINT-8200211(identity) rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O|mint:MINT-8200207(identity) - - - figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/07/21 2014/10/16 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 intact-crc:2E1DFA55FCEB88B8|rigid:Hxl0tRZjxyZDV/T+CWGKndmLr+o false fusion protein:?-?(MINT-8200212) fusion protein:?-?(MINT-8200208) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y283 uniprotkb:P62158 intact:EBI-751472|uniprotkb:Q5W0T6|uniprotkb:Q8IVX8|uniprotkb:Q9BRB9|uniprotkb:Q9Y488|uniprotkb:Q9Y498|uniprotkb:A2A2Y2|uniprotkb:Q2NKL0|ensembl:ENSP00000262457 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:invs_human(display_long)|uniprotkb:Inversion of embryo turning homolog(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym)|uniprotkb:INVS(gene name)|psi-mi:INVS(display_short)|uniprotkb:INV(gene name synonym)|uniprotkb:NPHP2(gene name synonym) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6959182|mint:MINT-8200174|imex:IM-15866-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055240.2|ensembl:ENSG00000119509(gene)|ensembl:ENST00000262457(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:MINT-8200181(identity) rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O|mint:MINT-8200176(identity) - - - figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/07/21 2014/10/16 rogid:GSK8P9P5/QrqxZL6oFgyWLdQ97Y9606 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 intact-crc:CA7E589FACC04DBA|rigid:UBc+D4Jgm6Y7ftHFeoK5lHVw7Xc false fusion protein:?-?(MINT-8200190) fusion protein:?-?(MINT-8200186) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N4P2 uniprotkb:Q9BPU9 intact:EBI-6958994|ensembl:ENSP00000386181|intact:MINT-8201091|uniprotkb:Q96NE6|uniprotkb:Q63HQ1 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 psi-mi:tt30b_human(display_long)|uniprotkb:TTC30B(gene name)|psi-mi:TTC30B(display_short) psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6959293|mint:MINT-8201154|imex:IM-15866-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196659(gene)|ensembl:ENST00000408939(transcript)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005929"(cilium)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0097542"(ciliary tip)|go:"GO:0120170"(intraciliary transport particle B binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039941|reactome:R-HSA-5620924|refseq:NP_689730.2|mint:MINT-8201162(identity) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2|mint:MINT-8201156(identity) - comment:mint comment:mint comment:homomint|comment:mint|figure legend:f1a f1b sf2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/07/21 2014/10/16 rogid:TCO8nxDWxu6IS5hkFa7H8XiQbyc9606 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 intact-crc:67680835E9A2CF5D|rigid:kbyG6dsUnEi1cBfG/KlMVAdasZ4 false fusion protein:?-?(MINT-8201165)|binding-associated region:1-364(MINT-8201163) binding-associated region:107-175(MINT-8201157)|fusion protein:?-?(MINT-8201159) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N4P2 uniprotkb:Q62559 intact:EBI-6958994|ensembl:ENSP00000386181|intact:MINT-8201091|uniprotkb:Q96NE6|uniprotkb:Q63HQ1 intact:EBI-6959048|ensembl:ENSMUSP00000018002|uniprotkb:Q8BTX3|uniprotkb:Q8CI16|intact:UNK-5463358|uniprotkb:Q3TK21 psi-mi:tt30b_human(display_long)|uniprotkb:TTC30B(gene name)|psi-mi:TTC30B(display_short) psi-mi:ift52_mouse(display_long)|uniprotkb:Ift52(gene name)|psi-mi:Ift52(display_short)|uniprotkb:Ngd5(gene name synonym)|uniprotkb:Protein NGD5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6959218|mint:MINT-8201133|imex:IM-15866-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196659(gene)|ensembl:ENST00000408939(transcript)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005929"(cilium)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0097542"(ciliary tip)|go:"GO:0120170"(intraciliary transport particle B binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039941|reactome:R-HSA-5620924|refseq:NP_689730.2|mint:MINT-8201136(identity) refseq:XP_006499604.1|ensembl:ENSMUSG00000017858(gene)|ensembl:ENSMUST00000018002(transcript)|go:"GO:0001841"(neural tube formation)|go:"GO:0001947"(heart looping)|interpro:IPR019196|interpro:IPR039975|rcsb pdb:5FMS|reactome:R-MMU-5610787|reactome:R-MMU-5620924|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035720"(intraciliary anterograde transport)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044292"(dendrite terminus)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0097733"(photoreceptor cell cilium)|go:"GO:0005813"(centrosome)|refseq:NP_742162.2|mint:MINT-8201137(identity) - comment:mint comment:mint comment:homomint|comment:mint|figure legend:f1d f1e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/07/21 2014/10/16 rogid:TCO8nxDWxu6IS5hkFa7H8XiQbyc9606 rogid:h6XuAO1JZm86wSXpV315g1X6bzM10090 intact-crc:C93D51073EF54C40|rigid:lHSFGWOYWVsxZJY2Qg4CrewqpFE false binding-associated region:1-364(MINT-8201151)|fusion protein:?-?(MINT-8201148) binding-associated region:219-426(MINT-8201145)|fusion protein:?-?(MINT-8201142) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BPU9 uniprotkb:Q9Y283 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 intact:EBI-751472|uniprotkb:Q5W0T6|uniprotkb:Q8IVX8|uniprotkb:Q9BRB9|uniprotkb:Q9Y488|uniprotkb:Q9Y498|uniprotkb:A2A2Y2|uniprotkb:Q2NKL0|ensembl:ENSP00000262457 psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:invs_human(display_long)|uniprotkb:Inversion of embryo turning homolog(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym)|uniprotkb:INVS(gene name)|psi-mi:INVS(display_short)|uniprotkb:INV(gene name synonym)|uniprotkb:NPHP2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6959351|mint:MINT-8201190|imex:IM-15866-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2|mint:MINT-8201192(identity) refseq:NP_055240.2|ensembl:ENSG00000119509(gene)|ensembl:ENST00000262457(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:MINT-8201196(identity) - comment:mint - comment:homomint|comment:mint|figure legend:f3c f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/07/21 2014/10/16 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 rogid:GSK8P9P5/QrqxZL6oFgyWLdQ97Y9606 intact-crc:622556E5FCE8A74C|rigid:K/eLBYYio+h/dXMW4xpSi/ld8yc false fusion protein:?-?(MINT-8201193)|binding-associated region:107-175(MINT-8201202) fusion protein:?-?(MINT-8201197)|binding-associated region:1-553(MINT-8201205) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BPU9 uniprotkb:Q9Y283 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 intact:EBI-751472|uniprotkb:Q5W0T6|uniprotkb:Q8IVX8|uniprotkb:Q9BRB9|uniprotkb:Q9Y488|uniprotkb:Q9Y498|uniprotkb:A2A2Y2|uniprotkb:Q2NKL0|ensembl:ENSP00000262457 psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:invs_human(display_long)|uniprotkb:Inversion of embryo turning homolog(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym)|uniprotkb:INVS(gene name)|psi-mi:INVS(display_short)|uniprotkb:INV(gene name synonym)|uniprotkb:NPHP2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21602787|imex:IM-15866|mint:MINT-8200088|doi:10.1038/emboj.2011.165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6959317|mint:MINT-8201172|imex:IM-15866-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2|mint:MINT-8201180(identity) refseq:NP_055240.2|ensembl:ENSG00000119509(gene)|ensembl:ENST00000262457(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:MINT-8201174(identity) - comment:mint - figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/07/21 2014/10/16 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 rogid:GSK8P9P5/QrqxZL6oFgyWLdQ97Y9606 intact-crc:B3A68103ED822181|rigid:K/eLBYYio+h/dXMW4xpSi/ld8yc false fusion protein:?-?(MINT-8201181) fusion protein:?-?(MINT-8201175) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)